Start with a safety question
Search by molecule, target, endpoint, modification, source, PMID, DOI, or off-target mechanism.
Primary workflows
Start from a citable release record, a mechanism question, a provenance packet, or a benchmark reuse task.
Safety-focused
ASO/siRNA toxicity and off-target evidence, not a broad RNA therapeutics catalog.
Source-grounded
Each release record links to source metadata, exact location, and curator audit trail.
Reusable
Bulk CSV/API downloads plus fixed Grade A/B benchmark splits.
Hepatic
Renal
Blood
Immune
Off-target
Local
Example Results
Open allSequence and Modification Evidence Coverage
Evidence lookup, not sequence-specific prediction.
OligoVigil parses A/C/G/T/U/N input and retrieves curated literature evidence for seed/off-target mechanisms. It does not perform genome or transcriptome alignment, 3'UTR seed-match scanning, or candidate risk ranking.
Complete sequence fields
Sequence-to-evidence lookup
Modification profile
Linked release evidence
Candidate evidence for curation
Safety Dossier Studio
Build a citable oligo safety dossier
Convert a candidate design context into release evidence, source provenance, benchmark hooks, and separated candidate gaps.
no de novo prediction
verified release only
candidate gaps separated
Dossier output
Live report summary, evidence graph, provenance policy, and export actions for the current query.
Evidence canvas
Design features connected to concerns, verified records, sources, and candidate gaps
Technical exports and data files
Dossier Packet
Exportable summary, graph, provenance, and benchmark reuse hooksRisk Matrix
Concern-level evidence state and next actionCitable release evidence
Candidate curation gaps
Validation Checklist
What a safety scientist should verify before reuseSearch
Sources
Molecules and cohorts
Candidates
Toxicity
Off-target
Query Examples
Example dataAsk OligoVigil
Grounded Question
Answer Guardrails
Interpreted Query
Whitelist query plan exposed for reproducible inspectionGrounded Records
Source Citations
Use Cases
Example Results
Selected Workflow
Release Status
Release Reuse Packet
Public Release Blockers
Reuse Risk Register
Field Completeness
Core Oligo Field Upgrade
Priority Queue
Blocking Gates
Readiness Gates
Release Batches
Curation and Trust
Loading curation protocol.
Checking release gates, audit coverage, provenance fields, and redistribution policy.
Independent Validation
Sampling Frame
Independent Check Fields
Audit Path
How users can reproduce the release boundaryProvenance Coverage
Release records onlyEvidence Grade Policy
A/B are benchmark eligible; C is contextualLicense and Redistribution Boundary
Raw article text is not redistributedAudit Method Summary
Counts from curation_auditKnown Limitations
Explicitly carried into the manuscript rather than hiddenCite OligoVigil
Preferred Citation
BibTeX
Archive DOI Readiness
Archive bundleAdoption Evidence
Quality Snapshot
API schemaRelease Readiness Gates
Curation Queue
Evidence Preview
Toxicity
Off-target
Provenance Audit
Citable Record
Citation
BibTeX
Benchmark Release Contract
Baseline Results
Run This Benchmark
Split Counts
Tasks
Agent Connect
Not Codex-specific.
OligoVigil exposes universal manifests, OpenAPI, MCP config, llms.txt, SDK clients, prompts, and templates so agentic clients, coding tools, and lightweight apps can connect without scraping the webpage or weakening evidence rules.
Connect From Any Tool
Universal Entrypoints
Installable Pack
Agent Guardrails
Reusable Workflows
Verified Sources
Source Detail
Verified Toxicity
Verified Off-target
Curation Queue Context
Unpromoted Candidate Context
Candidate rows are gap-finding context only and are not citable release evidence.
Molecules and Cohorts
Closest-work Audit
Integrated Tools
Most users do not need to read API code.
Use the integrated buttons below for the same evidence, benchmark, download, and triage workflows.
Generate safety triage report
Search evidence
Browse verified release
Open benchmark tools
Download evidence release
Download benchmark splits
Prepare curator review
Download full snapshot
Developer API details
Submit Evidence
Loading download catalog.
Preparing release files, recommended bundles, and checksum details.
Loading release files...