id,entity_table,entity_id,extraction_method,extractor_model_or_script,validation_status,curator_decision,curator_id,audit_note,audited_at
1,source_document,1,manual,none,verified,accept,editorial_seed_nonhuman,NAR official guideline source,2026-06-01T00:00:00Z
2,source_document,3,manual,none,verified,linkout_only,editorial_seed_nonhuman,Closest work; do not import raw records,2026-06-01T00:00:00Z
3,source_document,5,manual,none,verified,linkout_only,editorial_seed_nonhuman,High-overlap competitor; do not import raw records,2026-06-01T00:00:00Z
23,curation_candidate,881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,ni_jie,"Reject: source location supports RNase H-mediated COL6A3 silencing/MOA, not primary ASO off-target evidence.",2026-06-01T20:27:28+00:00
24,offtarget_evidence,11,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph tests near-complementary bulged duplex discrimination and supports reduced mismatch off-target liability.,2026-06-01T22:53:00+00:00
25,toxicity_endpoint,10,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results figure documents mitigation of acute CNS toxicity by guanine/hypoxanthine substitution in ASOs.,2026-06-01T22:53:00+00:00
26,toxicity_endpoint,11,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports nebulized siRNA knockdown with minimal cytotoxicity in THP-1 macrophage-like cells.,2026-06-01T22:53:00+00:00
27,toxicity_endpoint,12,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports dose-related CNS toxicity signs and mortality after RGLS4326 administration.,2026-06-01T22:53:00+00:00
28,toxicity_endpoint,13,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results safety section reports TEAEs after single- and multiple-dose inhaled SNS812 in healthy participants.,2026-06-01T22:53:00+00:00
29,toxicity_endpoint,14,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results cytotoxicity section directly assays ASO conjugate effects on cell viability.,2026-06-01T22:53:00+00:00
30,toxicity_endpoint,15,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results section supports low cytotoxic potential of siSNCA polymer nanoparticles in vitro.,2026-06-01T22:53:00+00:00
31,toxicity_endpoint,16,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results safety section reports adverse events during siRNA plus peginterferon clinical treatment.,2026-06-01T22:53:00+00:00
32,toxicity_endpoint,17,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results section reports H&E organ histology and ALT/AST/creatinine/BUN safety after siRNA nanoparticle dosing.,2026-06-01T22:53:00+00:00
33,toxicity_endpoint,18,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph measures nanocomplex cytotoxicity in tumor and normal bronchial epithelial cells.,2026-06-01T22:53:00+00:00
34,toxicity_endpoint,19,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results biosafety section reports histology and liver/kidney function tests for siRNA nanoparticles.,2026-06-01T22:53:00+00:00
35,toxicity_endpoint,20,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph explicitly frames RNA-seq as transcriptomic change and toxicity analysis after siRNADUX4 treatment.,2026-06-01T22:53:00+00:00
36,toxicity_endpoint,21,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results in vivo safety section reports organ histology and liver/kidney blood chemistry after siRNA EV treatment.,2026-06-01T22:53:00+00:00
37,toxicity_endpoint,22,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph directly evaluates immunological safety of siRNA-loaded milk EVs in PBMCs.,2026-06-01T22:53:00+00:00
38,toxicity_endpoint,23,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"PMC full text checked; Results paragraph reports no organ pathology, unchanged liver/kidney chemistry, and inflammatory-marker assessment.",2026-06-01T22:53:00+00:00
39,toxicity_endpoint,24,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph directly reports reduced acute CNS toxicity from ASO chemical modification.,2026-06-01T22:53:00+00:00
40,toxicity_endpoint,25,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports formulation-dependent prevention of acute neurotoxicity for CNS-administered oligonucleotides.,2026-06-01T22:53:00+00:00
41,toxicity_endpoint,26,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports ASO cytotoxicity testing in non-tumor fibroblasts and human cancer cell lines.,2026-06-01T22:53:00+00:00
42,toxicity_endpoint,27,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results in vivo toxicity section evaluates organ pathology after LNP-siTGFbetaRI treatment.,2026-06-01T22:53:00+00:00
43,toxicity_endpoint,28,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports adverse events during CT102 phase I dose-escalation follow-up.,2026-06-01T22:53:00+00:00
44,toxicity_endpoint,29,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results figure caption directly labels STAT3-siRNA gene silencing and cytotoxicity readouts.,2026-06-01T22:53:00+00:00
45,toxicity_endpoint,30,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph states siRNA polyplex conditions were below the cytotoxicity threshold.,2026-06-01T22:53:00+00:00
46,toxicity_endpoint,31,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results section measures apoptosis/cytotoxicity for polymeric solid-lipid siRNA nanoparticles.,2026-06-01T22:53:00+00:00
47,toxicity_endpoint,32,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results figure caption reports synthesis and cytotoxicity assays for PD-L1 siRNA nanovesicles.,2026-06-01T22:53:00+00:00
48,toxicity_endpoint,33,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph uses body-weight monitoring as an acute systemic tolerability readout for SWNT-siRNA conjugates.,2026-06-01T22:53:00+00:00
49,toxicity_endpoint,34,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports liver and kidney pathology after phosphorothioate oligonucleotide dosing.,2026-06-01T22:53:00+00:00
50,toxicity_endpoint,35,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports arrhythmia monitoring and serum chemistry after miR-125a-5p agomir treatment.,2026-06-01T22:53:00+00:00
51,toxicity_endpoint,36,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results safety analysis section reports systemic safety readouts for the siRNA-SiS formulation.,2026-06-01T22:53:00+00:00
52,toxicity_endpoint,37,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"PMC full text checked; Results paragraph reports non-toxic, non-inflammatory intramuscular siRNA delivery using RBC extracellular vesicles.",2026-06-01T22:53:00+00:00
53,toxicity_endpoint,38,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph directly links ASO sequence/modification to acute neurotoxicity.,2026-06-01T22:53:00+00:00
54,toxicity_endpoint,39,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results figure caption supports reduced LNA gapmer hepatotoxicity from nucleobase modification.,2026-06-01T22:53:00+00:00
55,toxicity_endpoint,40,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph describes rat toxicity studies showing improved therapeutic index from seed-pairing destabilization.,2026-06-01T22:53:00+00:00
56,toxicity_endpoint,41,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph links tissue accumulation of lipid-conjugated siRNA to non-specific gene modulation likely related to toxicity.,2026-06-01T22:53:00+00:00
57,toxicity_endpoint,42,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports elevated liver-toxicity markers after high-dose ALC-0315 LNP siRNA treatment.,2026-06-01T22:53:00+00:00
58,toxicity_endpoint,43,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results biocompatibility section reports cytotoxicity and hemolysis testing for siRNA nanoparticles.,2026-06-01T22:53:00+00:00
59,toxicity_endpoint,44,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports siRNA/CDplex-associated background toxicity and sequence-independent siRNA effect.,2026-06-01T22:53:00+00:00
60,toxicity_endpoint,45,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results toxicity assay section measures oligonucleotide cytotoxicity in human cell lines.,2026-06-01T22:53:00+00:00
61,toxicity_endpoint,46,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results in vitro biosafety section reports cell-viability testing for siRNA nanodroplets.,2026-06-01T22:53:00+00:00
62,toxicity_endpoint,47,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph evaluates CYP3A5 ASO renal safety markers in a proximal tubule microphysiological system.,2026-06-01T22:53:00+00:00
63,toxicity_endpoint,48,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports renal and hepatic safety markers after LNA/GalNAc ASO dosing.,2026-06-01T22:53:00+00:00
64,toxicity_endpoint,49,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports no BUN/creatinine changes while evaluating ASO kidney histology artifacts.,2026-06-01T22:53:00+00:00
65,toxicity_endpoint,50,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports absence of adverse phenotype after ICV LUNAR-REPU910 dosing.,2026-06-01T22:53:00+00:00
66,toxicity_endpoint,51,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph directly compares hepatotoxicity of ASO and LNPssPalmO-Phe-ASO formulations.,2026-06-01T22:53:00+00:00
67,toxicity_endpoint,52,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports incidence and dose percentage of ASO tolerability events across clinical studies.,2026-06-01T22:53:00+00:00
68,toxicity_endpoint,53,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results toxicity assessment reports in vivo organ histology after repeated dual-RGD carrier treatment.,2026-06-01T22:53:00+00:00
69,toxicity_endpoint,54,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports no kidney biomarker elevation for PMO-P6 up to tested doses.,2026-06-01T22:53:00+00:00
70,toxicity_endpoint,55,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports no skin allergy or systemic toxicity for sustained siMMP-9 hydrogel delivery.,2026-06-01T22:53:00+00:00
71,toxicity_endpoint,56,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph evaluates stereochemistry-dependent gapmer toxicity markers.,2026-06-01T22:53:00+00:00
72,toxicity_endpoint,57,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports cell viability for bioreducible LNP/ASO nanocomplexes across ASO doses.,2026-06-01T22:53:00+00:00
73,toxicity_endpoint,58,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports safety biomarkers and histology after tcDNA-ASO treatment.,2026-06-01T22:53:00+00:00
74,toxicity_endpoint,59,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph directly demonstrates GalNAc attenuation of AON nephrotoxicity potential.,2026-06-01T22:53:00+00:00
75,toxicity_endpoint,60,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph shows blocking siRNA-loaded RISC mitigates off-target-driven rat hepatotoxicity.,2026-06-01T22:53:00+00:00
76,toxicity_endpoint,61,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports an in vitro apoptosis assay linked to hepatotoxic LNA-ASOs.,2026-06-01T22:53:00+00:00
77,toxicity_endpoint,62,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph identifies extracellular EGF as an in vitro marker of AON-induced tubulotoxicity.,2026-06-01T22:53:00+00:00
78,toxicity_endpoint,63,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports in vivo gapmer hepatotoxicity and distinguishes gapmer from non-gapmer controls.,2026-06-01T22:53:00+00:00
79,toxicity_endpoint,64,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph links targeted long pre-mRNA down-regulation by ASO mixtures to hepatotoxicity.,2026-06-01T22:53:00+00:00
80,toxicity_endpoint,65,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports long-term efficacy and safety monitoring after PMO-GF dosing.,2026-06-01T22:53:00+00:00
81,toxicity_endpoint,66,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; Results paragraph reports mouse hepatotoxicity evaluation for LNA gapmer sequence motifs.,2026-06-01T22:53:00+00:00
82,curation_candidate,3441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: plant synthetic tasiRNA protocol; not therapeutic ASO/siRNA safety or off-target evidence,2026-06-01T22:53:00+00:00
83,curation_candidate,262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: news/commentary only; no primary safety evidence,2026-06-01T22:53:00+00:00
84,curation_candidate,3414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: tumor co-delivery efficacy section; no primary oligonucleotide safety endpoint at cited source,2026-06-01T22:53:00+00:00
85,curation_candidate,3658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: DOX/siRNA tumor-killing efficacy endpoint; no primary oligonucleotide safety evidence,2026-06-01T22:53:00+00:00
86,curation_candidate,209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: duplicate preprint superseded by curated final article candidate 207,2026-06-01T22:53:00+00:00
87,curation_candidate,8311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral AAV RNAi vector study outside synthetic oligonucleotide release scope,2026-06-01T22:53:00+00:00
88,curation_candidate,8434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: target-mediated disease-model liver injury after ASO knockdown, not intrinsic oligonucleotide safety evidence",2026-06-01T22:53:00+00:00
89,curation_candidate,212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review only; not primary evidence,2026-06-01T22:53:00+00:00
90,curation_candidate,634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review only; not primary evidence,2026-06-01T22:53:00+00:00
91,curation_candidate,1722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: AAV-expressed RNAi construct toxicity outside synthetic oligonucleotide release scope,2026-06-01T22:53:00+00:00
92,offtarget_evidence,12,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports seed-mediated off-target effect.,2026-06-01T23:22:20+00:00
93,toxicity_endpoint,67,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
94,toxicity_endpoint,68,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
95,toxicity_endpoint,69,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
96,toxicity_endpoint,70,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
97,toxicity_endpoint,71,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
98,toxicity_endpoint,72,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
99,toxicity_endpoint,73,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports neurotoxicity evidence.,2026-06-01T23:22:20+00:00
100,toxicity_endpoint,74,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
101,toxicity_endpoint,75,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
102,toxicity_endpoint,76,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
103,toxicity_endpoint,77,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
104,toxicity_endpoint,78,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
105,toxicity_endpoint,79,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
106,toxicity_endpoint,80,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports cytotoxicity evidence.,2026-06-01T23:22:20+00:00
107,toxicity_endpoint,81,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
108,toxicity_endpoint,82,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
109,toxicity_endpoint,83,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
110,toxicity_endpoint,84,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
111,offtarget_evidence,13,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hybridization/mismatch off-target effect.,2026-06-01T23:22:20+00:00
112,offtarget_evidence,14,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hybridization/mismatch off-target effect.,2026-06-01T23:22:20+00:00
113,offtarget_evidence,15,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports off-target evidence.,2026-06-01T23:22:20+00:00
114,toxicity_endpoint,85,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
115,toxicity_endpoint,86,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
116,toxicity_endpoint,87,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
117,toxicity_endpoint,88,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
118,toxicity_endpoint,89,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
119,toxicity_endpoint,90,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
120,toxicity_endpoint,91,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
121,toxicity_endpoint,92,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
122,toxicity_endpoint,93,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
123,toxicity_endpoint,94,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
124,toxicity_endpoint,95,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
125,toxicity_endpoint,96,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
126,toxicity_endpoint,97,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
127,toxicity_endpoint,98,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
128,toxicity_endpoint,99,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
129,toxicity_endpoint,100,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports safety/tolerability evidence.,2026-06-01T23:22:20+00:00
130,toxicity_endpoint,101,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports neurotoxicity evidence.,2026-06-01T23:22:20+00:00
131,toxicity_endpoint,102,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
132,toxicity_endpoint,103,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
133,toxicity_endpoint,104,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
134,toxicity_endpoint,105,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
135,toxicity_endpoint,106,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
136,toxicity_endpoint,107,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
137,toxicity_endpoint,108,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
138,offtarget_evidence,16,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports sequence-specificity/off-target evidence.,2026-06-01T23:22:20+00:00
139,offtarget_evidence,17,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports sequence-specificity/off-target evidence.,2026-06-01T23:22:20+00:00
140,offtarget_evidence,18,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports off-target evidence.,2026-06-01T23:22:20+00:00
141,toxicity_endpoint,109,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
142,toxicity_endpoint,110,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
143,toxicity_endpoint,111,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
144,toxicity_endpoint,112,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
145,toxicity_endpoint,113,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
146,toxicity_endpoint,114,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports safety/tolerability evidence.,2026-06-01T23:22:20+00:00
147,toxicity_endpoint,115,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
148,offtarget_evidence,19,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports seed-mediated off-target effect.,2026-06-01T23:22:20+00:00
149,toxicity_endpoint,116,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports safety/tolerability evidence.,2026-06-01T23:22:20+00:00
150,offtarget_evidence,20,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports seed-mediated off-target effect.,2026-06-01T23:22:20+00:00
151,offtarget_evidence,21,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports sequence-specificity/off-target evidence.,2026-06-01T23:22:20+00:00
152,offtarget_evidence,22,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports seed-mediated off-target effect.,2026-06-01T23:22:20+00:00
153,offtarget_evidence,23,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports seed-mediated off-target effect.,2026-06-01T23:22:20+00:00
154,offtarget_evidence,24,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports seed-mediated off-target effect.,2026-06-01T23:22:20+00:00
155,offtarget_evidence,25,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports seed-mediated off-target effect.,2026-06-01T23:22:20+00:00
156,offtarget_evidence,26,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hybridization/mismatch off-target effect.,2026-06-01T23:22:20+00:00
157,offtarget_evidence,27,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports seed-mediated off-target effect.,2026-06-01T23:22:20+00:00
158,offtarget_evidence,28,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports seed-mediated off-target effect.,2026-06-01T23:22:20+00:00
159,toxicity_endpoint,117,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
160,toxicity_endpoint,118,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
161,toxicity_endpoint,119,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports neurotoxicity evidence.,2026-06-01T23:22:20+00:00
162,toxicity_endpoint,120,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
163,toxicity_endpoint,121,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
164,toxicity_endpoint,122,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
165,toxicity_endpoint,123,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
166,toxicity_endpoint,124,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
167,toxicity_endpoint,125,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
168,toxicity_endpoint,126,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
169,toxicity_endpoint,127,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports neurotoxicity evidence.,2026-06-01T23:22:20+00:00
170,toxicity_endpoint,128,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports neurotoxicity evidence.,2026-06-01T23:22:20+00:00
171,toxicity_endpoint,129,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
172,toxicity_endpoint,130,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
173,toxicity_endpoint,131,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
174,toxicity_endpoint,132,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
175,toxicity_endpoint,133,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
176,toxicity_endpoint,134,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
177,toxicity_endpoint,135,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
178,toxicity_endpoint,136,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
179,toxicity_endpoint,137,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
180,toxicity_endpoint,138,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
181,toxicity_endpoint,139,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
182,toxicity_endpoint,140,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
183,toxicity_endpoint,141,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
184,toxicity_endpoint,142,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
185,toxicity_endpoint,143,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
186,toxicity_endpoint,144,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
187,toxicity_endpoint,145,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
188,toxicity_endpoint,146,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
189,toxicity_endpoint,147,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
190,toxicity_endpoint,148,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports neurotoxicity evidence.,2026-06-01T23:22:20+00:00
191,toxicity_endpoint,149,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports neurotoxicity evidence.,2026-06-01T23:22:20+00:00
192,toxicity_endpoint,150,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
193,toxicity_endpoint,151,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
194,toxicity_endpoint,152,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports renal safety evidence.,2026-06-01T23:22:20+00:00
195,toxicity_endpoint,153,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports platelet/bleeding safety evidence.,2026-06-01T23:22:20+00:00
196,toxicity_endpoint,154,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
197,toxicity_endpoint,155,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
198,toxicity_endpoint,156,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
199,toxicity_endpoint,157,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports hepatotoxicity evidence.,2026-06-01T23:22:20+00:00
200,toxicity_endpoint,158,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports immune activation evidence.,2026-06-01T23:22:20+00:00
201,toxicity_endpoint,159,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports neurotoxicity evidence.,2026-06-01T23:22:20+00:00
202,toxicity_endpoint,160,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,PMC full text checked; verified source supports neurotoxicity evidence.,2026-06-01T23:22:20+00:00
203,curation_candidate,9045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
204,curation_candidate,9052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
205,curation_candidate,1874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
206,curation_candidate,1590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
207,curation_candidate,1605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
208,curation_candidate,1612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
209,curation_candidate,3115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
210,curation_candidate,4643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
211,curation_candidate,4971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
212,curation_candidate,5344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
213,curation_candidate,5360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
214,curation_candidate,5467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
215,curation_candidate,5584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
216,curation_candidate,481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
217,curation_candidate,679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
218,curation_candidate,1614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
219,curation_candidate,1615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
220,curation_candidate,1616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
221,curation_candidate,1618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
222,curation_candidate,1621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
223,curation_candidate,1659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
224,curation_candidate,1664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
225,curation_candidate,1668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
226,curation_candidate,2188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
227,curation_candidate,2772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
228,curation_candidate,6105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
229,curation_candidate,6328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
230,curation_candidate,6542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
231,curation_candidate,6596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
232,curation_candidate,6623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
233,curation_candidate,6996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
234,curation_candidate,7363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
235,curation_candidate,7395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
236,curation_candidate,7418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
237,curation_candidate,7483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
238,curation_candidate,7562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
239,curation_candidate,7641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
240,curation_candidate,8797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
241,curation_candidate,8802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
242,curation_candidate,240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
243,curation_candidate,1870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
244,curation_candidate,2267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
245,curation_candidate,2854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
246,curation_candidate,7911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
247,curation_candidate,8083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
248,curation_candidate,8161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
249,curation_candidate,8302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
250,curation_candidate,8447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
251,curation_candidate,8535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
252,curation_candidate,8539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
253,curation_candidate,8918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
254,curation_candidate,10173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
255,curation_candidate,1333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
256,curation_candidate,1366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
257,curation_candidate,1693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
258,curation_candidate,2399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
259,curation_candidate,2439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
260,curation_candidate,4177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
261,curation_candidate,8575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
262,curation_candidate,8591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
263,curation_candidate,8689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
264,curation_candidate,8945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
265,curation_candidate,946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
266,curation_candidate,1528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
267,curation_candidate,2513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
268,curation_candidate,1729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
269,curation_candidate,1735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
270,curation_candidate,1755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
271,curation_candidate,9571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
272,curation_candidate,1011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
273,curation_candidate,1646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
274,curation_candidate,2273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
275,curation_candidate,1753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
276,curation_candidate,104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
277,curation_candidate,121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: GalNAc-siRNA pharmacokinetic/distribution evidence, not off-target evidence",2026-06-01T23:22:20+00:00
278,curation_candidate,1094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
279,curation_candidate,1124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
280,curation_candidate,2064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: siRNA efficacy/lifespan biology, not off-target evidence",2026-06-01T23:22:20+00:00
281,curation_candidate,3112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: siRNA design/efficacy testing, not explicit off-target evidence",2026-06-01T23:22:20+00:00
282,curation_candidate,3253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: protocol article; not release evidence,2026-06-01T23:22:20+00:00
283,curation_candidate,5985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
284,curation_candidate,9136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
285,curation_candidate,1135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
286,curation_candidate,2717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
287,curation_candidate,2757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
288,curation_candidate,3515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
289,curation_candidate,3532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
290,curation_candidate,3682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
291,curation_candidate,3885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
292,curation_candidate,3942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
293,curation_candidate,6225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: plant/fungal RNAi application, outside therapeutic oligonucleotide scope",2026-06-01T23:22:20+00:00
294,curation_candidate,6749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: plant pathogen dsRNA uptake/silencing, outside therapeutic oligonucleotide scope",2026-06-01T23:22:20+00:00
295,curation_candidate,7277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
296,curation_candidate,7617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
297,curation_candidate,7664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
298,curation_candidate,8863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
299,curation_candidate,9048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
300,curation_candidate,9152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
301,curation_candidate,9153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
302,curation_candidate,9159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
303,curation_candidate,869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
304,curation_candidate,880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
305,curation_candidate,3961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
306,curation_candidate,3967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
307,curation_candidate,4007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: delivery/efficacy modifier study, not off-target evidence",2026-06-01T23:22:20+00:00
308,curation_candidate,4159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
309,curation_candidate,8166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: SOD1 efficacy optimization without explicit off-target endpoint at source,2026-06-01T23:22:20+00:00
310,curation_candidate,8340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
311,curation_candidate,8845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
312,curation_candidate,8866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
313,curation_candidate,2897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: shRNA screening context outside synthetic therapeutic oligonucleotide release scope,2026-06-01T23:22:20+00:00
314,curation_candidate,4261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: macrophage siRNA silencing efficacy, not off-target evidence",2026-06-01T23:22:20+00:00
315,curation_candidate,8728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
316,curation_candidate,942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
317,curation_candidate,1888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: siRNA antitumor activity/release profile, not off-target evidence",2026-06-01T23:22:20+00:00
318,curation_candidate,2470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: introduction/background only, not primary off-target evidence",2026-06-01T23:22:20+00:00
319,curation_candidate,4313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: siRNA activity/asymmetry data, not explicit off-target evidence",2026-06-01T23:22:20+00:00
320,curation_candidate,1796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
321,curation_candidate,1994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
322,curation_candidate,2532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
323,curation_candidate,2995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
324,curation_candidate,2996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
325,curation_candidate,4460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
326,curation_candidate,8875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
327,curation_candidate,8877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
328,curation_candidate,2557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
329,curation_candidate,9496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
330,curation_candidate,9511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
331,curation_candidate,9616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
332,curation_candidate,322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
333,curation_candidate,1065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
334,curation_candidate,2038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
335,curation_candidate,3206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
336,curation_candidate,5364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
337,curation_candidate,9134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
338,curation_candidate,2098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
339,curation_candidate,2771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
340,curation_candidate,3449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
341,curation_candidate,3555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: conditional-siRNA design/efficacy anchor, not a safety endpoint",2026-06-01T23:22:20+00:00
342,curation_candidate,3725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
343,curation_candidate,3924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
344,curation_candidate,9185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
345,curation_candidate,859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
346,curation_candidate,2274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
347,curation_candidate,2364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
348,curation_candidate,4149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
349,curation_candidate,8339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: delivery/efficacy biology anchor, not primary safety evidence",2026-06-01T23:22:20+00:00
350,curation_candidate,8844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: DNA damage efficacy mechanism, not oligonucleotide safety evidence",2026-06-01T23:22:20+00:00
351,curation_candidate,9286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
352,curation_candidate,304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: non-primary narrative/clinical-status discussion; no direct original safety result at source anchor,2026-06-01T23:22:20+00:00
353,curation_candidate,8960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: broad toxicity discussion/review-style section, not primary evidence",2026-06-01T23:22:20+00:00
354,curation_candidate,1984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
355,curation_candidate,2491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
356,curation_candidate,762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
357,curation_candidate,2501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: RNAi-mediated plum food-safety study, outside therapeutic oligonucleotide scope",2026-06-01T23:22:20+00:00
358,curation_candidate,1898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: plant genome-editing safety assessment, outside therapeutic oligonucleotide scope",2026-06-01T23:22:20+00:00
359,curation_candidate,462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
360,curation_candidate,989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
361,curation_candidate,2676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
362,curation_candidate,2681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
363,curation_candidate,2682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
364,curation_candidate,2704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
365,curation_candidate,3067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
366,curation_candidate,3145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
367,curation_candidate,3270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
368,curation_candidate,4709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
369,curation_candidate,4759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
370,curation_candidate,4827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
371,curation_candidate,4834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
372,curation_candidate,4865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
373,curation_candidate,4886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
374,curation_candidate,4951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
375,curation_candidate,5069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
376,curation_candidate,5371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
377,curation_candidate,5405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
378,curation_candidate,5498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
379,curation_candidate,5526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
380,curation_candidate,5715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
381,curation_candidate,9025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
382,curation_candidate,9644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
383,curation_candidate,9651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
384,curation_candidate,9658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
385,curation_candidate,9668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
386,curation_candidate,836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
387,curation_candidate,1954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
388,curation_candidate,2100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
389,curation_candidate,2714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
390,curation_candidate,2734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
391,curation_candidate,2752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
392,curation_candidate,2773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
393,curation_candidate,2788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
394,curation_candidate,2800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
395,curation_candidate,2810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
396,curation_candidate,6227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
397,curation_candidate,6229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
398,curation_candidate,6248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
399,curation_candidate,6506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
400,curation_candidate,6555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
401,curation_candidate,6773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
402,curation_candidate,6885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
403,curation_candidate,6980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
404,curation_candidate,7053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
405,curation_candidate,7592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
406,curation_candidate,9036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
407,curation_candidate,9717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
408,curation_candidate,9732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
409,curation_candidate,9771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
410,curation_candidate,9785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
411,curation_candidate,9798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
412,curation_candidate,9880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
413,curation_candidate,9906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
414,curation_candidate,9958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
415,curation_candidate,9970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
416,curation_candidate,1285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
417,curation_candidate,2300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
418,curation_candidate,2307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
419,curation_candidate,2825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
420,curation_candidate,2861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
421,curation_candidate,8259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
422,curation_candidate,9076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
423,curation_candidate,10067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
424,curation_candidate,2379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
425,curation_candidate,2429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
426,curation_candidate,2434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
427,curation_candidate,2442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
428,curation_candidate,2883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
429,curation_candidate,2886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
430,curation_candidate,2890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
431,curation_candidate,2891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
432,curation_candidate,2921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
433,curation_candidate,9095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
434,curation_candidate,10262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
435,curation_candidate,1983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
436,curation_candidate,1989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
437,curation_candidate,2929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
438,curation_candidate,2938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
439,curation_candidate,2942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
440,curation_candidate,2945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
441,curation_candidate,2947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
442,curation_candidate,2952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
443,curation_candidate,2955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
444,curation_candidate,2958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
445,curation_candidate,1995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
446,curation_candidate,2961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
447,curation_candidate,2966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
448,curation_candidate,2973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
449,curation_candidate,2974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
450,curation_candidate,2981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
451,curation_candidate,9103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
452,curation_candidate,9104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
453,curation_candidate,9109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
454,curation_candidate,3009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
455,curation_candidate,3010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
456,curation_candidate,3016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
457,curation_candidate,3018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
458,curation_candidate,3025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
459,curation_candidate,9110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
460,curation_candidate,9112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
461,curation_candidate,9115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
462,curation_candidate,9116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
463,curation_candidate,9123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
464,curation_candidate,8983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
465,curation_candidate,9129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
466,curation_candidate,4520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
467,curation_candidate,4541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic hybridization probe design, not therapeutic off-target evidence",2026-06-01T23:22:20+00:00
468,curation_candidate,2013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
469,curation_candidate,191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
470,curation_candidate,338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
471,curation_candidate,339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
472,curation_candidate,366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
473,curation_candidate,986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
474,curation_candidate,2019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
475,curation_candidate,2068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
476,curation_candidate,2085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
477,curation_candidate,2657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
478,curation_candidate,2658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
479,curation_candidate,2660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
480,curation_candidate,2662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
481,curation_candidate,2673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
482,curation_candidate,2677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
483,curation_candidate,2680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
484,curation_candidate,4856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
485,curation_candidate,4952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
486,curation_candidate,5129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
487,curation_candidate,5307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
488,curation_candidate,5399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
489,curation_candidate,5429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
490,curation_candidate,5441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
491,curation_candidate,5450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
492,curation_candidate,5553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
493,curation_candidate,9683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
494,curation_candidate,9691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
495,curation_candidate,9712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
496,curation_candidate,81,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
497,curation_candidate,151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
498,curation_candidate,403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
499,curation_candidate,627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
500,curation_candidate,816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
501,curation_candidate,1500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
502,curation_candidate,2099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
503,curation_candidate,2104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
504,curation_candidate,2204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
505,curation_candidate,2707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
506,curation_candidate,2708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
507,curation_candidate,2715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
508,curation_candidate,2723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
509,curation_candidate,2726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
510,curation_candidate,2727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
511,curation_candidate,2750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
512,curation_candidate,2769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
513,curation_candidate,2777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
514,curation_candidate,2782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
515,curation_candidate,2804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
516,curation_candidate,3562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
517,curation_candidate,6180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
518,curation_candidate,6196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
519,curation_candidate,6436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
520,curation_candidate,6659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
521,curation_candidate,6665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
522,curation_candidate,6674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
523,curation_candidate,6734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
524,curation_candidate,6862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
525,curation_candidate,6932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
526,curation_candidate,6970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
527,curation_candidate,7148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
528,curation_candidate,7376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
529,curation_candidate,7551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
530,curation_candidate,7599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
531,curation_candidate,7629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
532,curation_candidate,7768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
533,curation_candidate,7792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
534,curation_candidate,8883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
535,curation_candidate,9030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
536,curation_candidate,9033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
537,curation_candidate,9044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
538,curation_candidate,9046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
539,curation_candidate,9183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
540,curation_candidate,9751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
541,curation_candidate,9794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
542,curation_candidate,9833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
543,curation_candidate,1280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
544,curation_candidate,1284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
545,curation_candidate,1675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
546,curation_candidate,2314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
547,curation_candidate,2350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
548,curation_candidate,2856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
549,curation_candidate,2860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
550,curation_candidate,7892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
551,curation_candidate,8055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
552,curation_candidate,8182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
553,curation_candidate,8256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
554,curation_candidate,8383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
555,curation_candidate,8481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
556,curation_candidate,8546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
557,curation_candidate,9081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
558,curation_candidate,9085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
559,curation_candidate,10066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
560,curation_candidate,928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
561,curation_candidate,1357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
562,curation_candidate,2378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
563,curation_candidate,2445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
564,curation_candidate,2898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
565,curation_candidate,2909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
566,curation_candidate,8583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
567,curation_candidate,8715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
568,curation_candidate,8939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
569,curation_candidate,9400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
570,curation_candidate,10301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
571,curation_candidate,1041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
572,curation_candidate,2483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
573,curation_candidate,8965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
574,curation_candidate,9097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
575,curation_candidate,2506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
576,curation_candidate,1044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
577,curation_candidate,9455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
578,curation_candidate,2580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
579,curation_candidate,4563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
580,curation_candidate,2690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: developmental transcriptome/RNAi gene characterization, outside release scope",2026-06-01T23:22:20+00:00
581,curation_candidate,6064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
582,curation_candidate,444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: STAT3 ASO efficacy/survival endpoint, not off-target evidence",2026-06-01T23:22:20+00:00
583,curation_candidate,1390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
584,curation_candidate,3574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
585,curation_candidate,2003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
586,curation_candidate,9666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
587,curation_candidate,2833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
588,curation_candidate,7311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
589,curation_candidate,7835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
590,curation_candidate,1010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: dsRNA cotton/non-target organism transcriptome study, outside therapeutic oligonucleotide scope",2026-06-01T23:22:20+00:00
591,curation_candidate,3439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: plant RNAi/allergen study, outside therapeutic oligonucleotide scope",2026-06-01T23:22:20+00:00
592,curation_candidate,8,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: software/tool introduction, not primary off-target evidence",2026-06-01T23:22:20+00:00
593,curation_candidate,1524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
594,curation_candidate,2447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
595,curation_candidate,2926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no explicit ASO/siRNA/oligonucleotide off-target evidence at source anchor,2026-06-01T23:22:20+00:00
596,curation_candidate,9001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
597,curation_candidate,254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
598,curation_candidate,343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
599,curation_candidate,390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: gene therapy safety profile, not ASO/siRNA/oligonucleotide evidence",2026-06-01T23:22:20+00:00
600,curation_candidate,579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
601,curation_candidate,610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
602,curation_candidate,667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
603,curation_candidate,671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
604,curation_candidate,1588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
605,curation_candidate,2024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
606,curation_candidate,2034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: AAV-expressed RNAi gene therapy outside synthetic oligonucleotide release scope,2026-06-01T23:22:20+00:00
607,curation_candidate,2050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
608,curation_candidate,2075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
609,curation_candidate,3148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
610,curation_candidate,3159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
611,curation_candidate,3220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
612,curation_candidate,3306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
613,curation_candidate,4652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
614,curation_candidate,4833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
615,curation_candidate,4982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
616,curation_candidate,5046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
617,curation_candidate,5271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
618,curation_candidate,5313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
619,curation_candidate,5349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
620,curation_candidate,5677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
621,curation_candidate,5756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
622,curation_candidate,5834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
623,curation_candidate,6001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: agricultural dsRNA/fungal-disease application, outside release scope",2026-06-01T23:22:20+00:00
624,curation_candidate,673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
625,curation_candidate,819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
626,curation_candidate,847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
627,curation_candidate,1156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
628,curation_candidate,1222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
629,curation_candidate,1501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
630,curation_candidate,1503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
631,curation_candidate,1543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
632,curation_candidate,1629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
633,curation_candidate,1635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
634,curation_candidate,1643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
635,curation_candidate,1654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
636,curation_candidate,1656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
637,curation_candidate,1657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
638,curation_candidate,2142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
639,curation_candidate,2157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
640,curation_candidate,2208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
641,curation_candidate,3372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: discussion/efficacy material only; source location unsupported for safety evidence,2026-06-01T23:22:20+00:00
642,curation_candidate,3376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
643,curation_candidate,3506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: discussion/future safety statement only, no primary safety result at source anchor",2026-06-01T23:22:20+00:00
644,curation_candidate,3601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
645,curation_candidate,3847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
646,curation_candidate,6074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
647,curation_candidate,6121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
648,curation_candidate,6464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
649,curation_candidate,6592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
650,curation_candidate,6593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
651,curation_candidate,6722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
652,curation_candidate,6728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
653,curation_candidate,6916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
654,curation_candidate,7142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
655,curation_candidate,7458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
656,curation_candidate,7498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
657,curation_candidate,7535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
658,curation_candidate,7561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
659,curation_candidate,7650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
660,curation_candidate,7824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
661,curation_candidate,8779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
662,curation_candidate,8804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
663,curation_candidate,9059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
664,curation_candidate,9843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
665,curation_candidate,451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
666,curation_candidate,855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
667,curation_candidate,857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
668,curation_candidate,885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/commentary/design/guidance only; no primary release evidence,2026-06-01T23:22:20+00:00
669,curation_candidate,1296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
670,curation_candidate,1508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
671,curation_candidate,1522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
672,curation_candidate,1672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
673,curation_candidate,1679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
674,curation_candidate,2283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
675,curation_candidate,2341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
676,curation_candidate,2362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
677,curation_candidate,3973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
678,curation_candidate,3990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
679,curation_candidate,4115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
680,curation_candidate,7888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background only; no primary safety evidence at source anchor,2026-06-01T23:22:20+00:00
681,curation_candidate,8063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
682,curation_candidate,8179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
683,curation_candidate,8284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
684,curation_candidate,8511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
685,curation_candidate,8811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality/model; not therapeutic ASO/siRNA/oligonucleotide safety or off-target evidence,2026-06-01T23:22:20+00:00
686,curation_candidate,9350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
687,curation_candidate,10145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
688,curation_candidate,10203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
689,curation_candidate,250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
690,curation_candidate,925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
691,curation_candidate,1346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary ASO/siRNA/oligonucleotide safety evidence at source anchor,2026-06-01T23:22:20+00:00
692,toxicity_endpoint,161,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
693,toxicity_endpoint,162,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
694,toxicity_endpoint,163,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for cell viability/cytotoxicity; location=2. Results > 2.5. Cell Viability; paragraph 14.,2026-06-01T23:45:02+00:00
695,toxicity_endpoint,164,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
696,toxicity_endpoint,165,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=DISCUSSION; paragraph 52.,2026-06-01T23:45:02+00:00
697,toxicity_endpoint,166,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and discussion > Characterization of LHHK LNPs for morphology, toxicity, serum stability, and hemolytic assay; paragraph 33.",2026-06-01T23:45:02+00:00
698,toxicity_endpoint,167,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results > Safety and tolerability; paragraph 28.,2026-06-01T23:45:02+00:00
699,toxicity_endpoint,168,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and discussion > The most toxic 6mer seeds differ slightly between human and mouse; paragraph 6.,2026-06-01T23:45:02+00:00
700,toxicity_endpoint,169,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and discussion > In vitro inhibition of siTNFα; paragraph 21.,2026-06-01T23:45:02+00:00
701,toxicity_endpoint,170,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 36.,2026-06-01T23:45:02+00:00
702,toxicity_endpoint,171,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
703,toxicity_endpoint,172,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=4. Discussion; paragraph 49.,2026-06-01T23:45:02+00:00
704,toxicity_endpoint,173,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=DISCUSSION; paragraph 40.,2026-06-01T23:45:02+00:00
705,toxicity_endpoint,174,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results > Cytotoxicity tests; paragraph 28.,2026-06-01T23:45:02+00:00
706,toxicity_endpoint,175,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 36.,2026-06-01T23:45:02+00:00
707,toxicity_endpoint,176,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
708,toxicity_endpoint,177,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
709,toxicity_endpoint,178,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 23.,2026-06-01T23:45:02+00:00
710,toxicity_endpoint,179,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 27.,2026-06-01T23:45:02+00:00
711,toxicity_endpoint,180,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=DISCUSSION; paragraph 39.,2026-06-01T23:45:02+00:00
712,toxicity_endpoint,181,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract > Results; paragraph 3.,2026-06-01T23:45:02+00:00
713,toxicity_endpoint,182,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and Discussion > Cytotoxicity; paragraph 5.,2026-06-01T23:45:02+00:00
714,toxicity_endpoint,183,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=DISCUSSION; paragraph 65.,2026-06-01T23:45:02+00:00
715,toxicity_endpoint,184,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
716,toxicity_endpoint,185,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 33.,2026-06-01T23:45:02+00:00
717,toxicity_endpoint,186,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and discussion > PMO delivery in C2C12 myoblast cell lines expressing GFP/hDysE50; paragraph 17.,2026-06-01T23:45:02+00:00
718,toxicity_endpoint,187,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=3. Results > 3.2. Safety results; paragraph 15.,2026-06-01T23:45:02+00:00
719,toxicity_endpoint,188,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
720,toxicity_endpoint,189,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 38.,2026-06-01T23:45:02+00:00
721,toxicity_endpoint,190,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=4. Discussion; paragraph 28.,2026-06-01T23:45:02+00:00
722,toxicity_endpoint,191,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
723,toxicity_endpoint,192,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for renal safety; location=Results > Safety; paragraph 23.,2026-06-01T23:45:02+00:00
724,offtarget_evidence,29,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for transcriptome-level off-target effect; location=Results and Discussion > Rational Design and Optimization of siRNA Candidates for Targeted SKP2 Silencing in Breast Cancer; paragraph 30.,2026-06-01T23:45:02+00:00
725,offtarget_evidence,30,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for transcriptome-level off-target effect; location=Discussion; paragraph 31.,2026-06-01T23:45:02+00:00
726,offtarget_evidence,31,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for transcriptome-level off-target effect; location=Conclusions; paragraph 26.,2026-06-01T23:45:02+00:00
727,offtarget_evidence,32,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for off-target evidence; location=Results and discussion > Limitations and prospects; paragraph 50.,2026-06-01T23:45:02+00:00
728,offtarget_evidence,33,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for seed-mediated off-target effect; location=Discussion; paragraph 15.,2026-06-01T23:45:02+00:00
729,offtarget_evidence,34,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for off-target evidence; location=Discussion; paragraph 22.,2026-06-01T23:45:02+00:00
730,offtarget_evidence,35,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for seed-mediated off-target effect; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
731,offtarget_evidence,36,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for transcriptome-level off-target effect; location=Discussion; paragraph 62.,2026-06-01T23:45:02+00:00
732,offtarget_evidence,37,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for off-target evidence; location=RESULTS AND DISCUSSION > TOXcms Identifies Off-target Effects of Genetic Knockdown.; paragraph 28.,2026-06-01T23:45:02+00:00
733,offtarget_evidence,38,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for off-target evidence; location=Discussion; paragraph 40.,2026-06-01T23:45:02+00:00
734,offtarget_evidence,39,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for off-target evidence; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
735,offtarget_evidence,40,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide offtarget evidence for off-target evidence; location=RESULTS AND DISCUSSION > Gene silencing by gymnotic delivery is a general phenomenon; paragraph 15.,2026-06-01T23:45:02+00:00
736,toxicity_endpoint,193,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 52.,2026-06-01T23:45:02+00:00
737,toxicity_endpoint,194,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results > Tolerability and safety profiles; paragraph 24.,2026-06-01T23:45:02+00:00
738,toxicity_endpoint,195,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
739,toxicity_endpoint,196,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and discussion > In vitro anti-fibrotic effect validation of ASO and characterization of ZMO-E5-NPs-ASO properties; paragraph 38.,2026-06-01T23:45:02+00:00
740,toxicity_endpoint,197,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Conclusions; paragraph 92.,2026-06-01T23:45:02+00:00
741,toxicity_endpoint,198,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for renal safety; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
742,toxicity_endpoint,199,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 44.,2026-06-01T23:45:02+00:00
743,toxicity_endpoint,200,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for renal safety; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
744,toxicity_endpoint,201,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for renal safety; location=Results > Distinct and shared gene expression changes occur following PAX2 and PAX8 knockdowns; Figure 5 caption.,2026-06-01T23:45:02+00:00
745,toxicity_endpoint,202,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 30.,2026-06-01T23:45:02+00:00
746,toxicity_endpoint,203,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=3. Results and Discussion > 3.2. Cytotoxicity of LNP-siN.C./siTNF-α and LNP-siN.C./siTNF-α-HCQ; paragraph 26.,2026-06-01T23:45:02+00:00
747,toxicity_endpoint,204,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=3. Discussion; paragraph 24.,2026-06-01T23:45:02+00:00
748,toxicity_endpoint,205,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and discussion > Cell viability; paragraph 39.,2026-06-01T23:45:02+00:00
749,toxicity_endpoint,206,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
750,toxicity_endpoint,207,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for immune activation; location=Abstract; paragraph 2.,2026-06-01T23:45:02+00:00
751,toxicity_endpoint,208,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for neurotoxicity; location=Discussion; paragraph 30.,2026-06-01T23:45:02+00:00
752,toxicity_endpoint,209,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
753,toxicity_endpoint,210,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results > Integrated safety analysis: AEs; paragraph 26.,2026-06-01T23:45:02+00:00
754,toxicity_endpoint,211,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for renal safety; location=Discussion; paragraph 26.,2026-06-01T23:45:02+00:00
755,toxicity_endpoint,212,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Conclusion; paragraph 65.,2026-06-01T23:45:02+00:00
756,toxicity_endpoint,213,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and Discussion > In Vivo GFP-pDNA Delivery by TP-SL@PB; paragraph 46.,2026-06-01T23:45:02+00:00
757,toxicity_endpoint,214,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and Discussion > Cell uptake and toxicity of siRNA@NP@ND in vitro; paragraph 12.,2026-06-01T23:45:02+00:00
758,toxicity_endpoint,215,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and discussion > Anti-metastasis and in vivo biosafety evaluation; paragraph 28.,2026-06-01T23:45:02+00:00
759,toxicity_endpoint,216,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and Discussion > Enhanced Cellular Uptake And Neurospecificity of Targeted Polyplexes; paragraph 14.,2026-06-01T23:45:02+00:00
760,toxicity_endpoint,217,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results > Platelets deliver TP53 SiRNA into renal tubule cells and protect them from CDDP-induced toxicity > EVs released by platelets transfer TP53 SiRNA into renal tubular cells; paragraph 39.,2026-06-01T23:45:02+00:00
761,toxicity_endpoint,218,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 46.,2026-06-01T23:45:02+00:00
762,toxicity_endpoint,219,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for renal safety; location=Discussion; paragraph 48.,2026-06-01T23:45:02+00:00
763,toxicity_endpoint,220,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for renal safety; location=Abstract > Results; paragraph 3.,2026-06-01T23:45:02+00:00
764,toxicity_endpoint,221,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 47.,2026-06-01T23:45:02+00:00
765,toxicity_endpoint,222,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
766,toxicity_endpoint,223,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
767,toxicity_endpoint,224,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=3. Discussion > 3.1. Descriptive Analysis; paragraph 18.,2026-06-01T23:45:02+00:00
768,toxicity_endpoint,225,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results and Discussion > cGAS Is Involved in the Immune Recognition of RNA/DNA Fibers; paragraph 26.,2026-06-01T23:45:02+00:00
769,toxicity_endpoint,226,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Materials and methods > Patient samples; paragraph 30.,2026-06-01T23:45:02+00:00
770,toxicity_endpoint,227,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 26.,2026-06-01T23:45:02+00:00
771,toxicity_endpoint,228,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=DISCUSSION; paragraph 37.,2026-06-01T23:45:02+00:00
772,toxicity_endpoint,229,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=Results > Safety outcomes; paragraph 13.,2026-06-01T23:45:02+00:00
773,toxicity_endpoint,230,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for renal safety; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
774,toxicity_endpoint,231,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 35.,2026-06-01T23:45:02+00:00
775,toxicity_endpoint,232,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for renal safety; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
776,toxicity_endpoint,233,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 29.,2026-06-01T23:45:02+00:00
777,toxicity_endpoint,234,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
778,toxicity_endpoint,235,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Results > PS- and ME/PS- modified oligonucleotides decrease platelet concentration in vitro; paragraph 29.,2026-06-01T23:45:02+00:00
779,toxicity_endpoint,236,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for immune activation; location=3. Results > 3.5. Reduced Viability of Target Cells; paragraph 49.,2026-06-01T23:45:02+00:00
780,toxicity_endpoint,237,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=4. Discussion > 4.2. Supplemented Transfection Medium Stabilizes Nanocomplexes but Harms Human Respiratory Epithelial Cells; paragraph 34.,2026-06-01T23:45:02+00:00
781,toxicity_endpoint,238,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=DISCUSSION; paragraph 57.,2026-06-01T23:45:02+00:00
782,toxicity_endpoint,239,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Materials and Methods > AON administration; FIG. 1. caption.,2026-06-01T23:45:02+00:00
783,toxicity_endpoint,240,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 36.,2026-06-01T23:45:02+00:00
784,toxicity_endpoint,241,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 26.,2026-06-01T23:45:02+00:00
785,toxicity_endpoint,242,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Discussion; paragraph 21.,2026-06-01T23:45:02+00:00
786,toxicity_endpoint,243,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=Abstract; paragraph 1.,2026-06-01T23:45:02+00:00
787,toxicity_endpoint,244,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: full text source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=Results; paragraph 15.,2026-06-01T23:45:02+00:00
788,offtarget_evidence,41,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for seed-mediated off-target effect; location=PubMed abstract.,2026-06-01T23:45:02+00:00
789,offtarget_evidence,42,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for seed-mediated off-target effect; location=PubMed abstract.,2026-06-01T23:45:02+00:00
790,offtarget_evidence,43,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for off-target evidence; location=PubMed abstract.,2026-06-01T23:45:02+00:00
791,offtarget_evidence,44,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for transcriptome-level off-target effect; location=PubMed abstract.,2026-06-01T23:45:02+00:00
792,offtarget_evidence,45,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for hybridization/mismatch off-target effect; location=PubMed abstract.,2026-06-01T23:45:02+00:00
793,offtarget_evidence,46,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for seed-mediated off-target effect; location=PubMed abstract.,2026-06-01T23:45:02+00:00
794,offtarget_evidence,47,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for transcriptome-level off-target effect; location=PubMed abstract.,2026-06-01T23:45:02+00:00
795,offtarget_evidence,48,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for off-target evidence; location=PubMed abstract.,2026-06-01T23:45:02+00:00
796,offtarget_evidence,49,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for hybridization/mismatch off-target effect; location=PubMed abstract.,2026-06-01T23:45:02+00:00
797,offtarget_evidence,50,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for transcriptome-level off-target effect; location=PubMed abstract.,2026-06-01T23:45:02+00:00
798,toxicity_endpoint,245,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
799,toxicity_endpoint,246,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
800,toxicity_endpoint,247,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
801,toxicity_endpoint,248,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
802,toxicity_endpoint,249,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
803,toxicity_endpoint,250,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=PubMed abstract.,2026-06-01T23:45:02+00:00
804,toxicity_endpoint,251,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
805,toxicity_endpoint,252,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
806,toxicity_endpoint,253,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
807,toxicity_endpoint,254,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
808,toxicity_endpoint,255,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
809,toxicity_endpoint,256,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for renal safety; location=PubMed abstract.,2026-06-01T23:45:02+00:00
810,toxicity_endpoint,257,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for renal safety; location=PubMed abstract.,2026-06-01T23:45:02+00:00
811,toxicity_endpoint,258,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
812,toxicity_endpoint,259,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
813,toxicity_endpoint,260,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
814,toxicity_endpoint,261,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
815,toxicity_endpoint,262,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
816,toxicity_endpoint,263,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
817,toxicity_endpoint,264,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=PubMed abstract.,2026-06-01T23:45:02+00:00
818,toxicity_endpoint,265,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
819,toxicity_endpoint,266,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
820,toxicity_endpoint,267,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract sentence 5.,2026-06-01T23:45:02+00:00
821,toxicity_endpoint,268,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
822,toxicity_endpoint,269,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for toxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
823,toxicity_endpoint,270,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
824,toxicity_endpoint,271,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
825,toxicity_endpoint,272,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for cell viability/cytotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
826,toxicity_endpoint,273,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
827,toxicity_endpoint,274,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
828,toxicity_endpoint,275,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
829,toxicity_endpoint,276,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
830,toxicity_endpoint,277,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
831,toxicity_endpoint,278,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
832,toxicity_endpoint,279,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
833,toxicity_endpoint,280,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
834,toxicity_endpoint,281,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
835,toxicity_endpoint,282,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
836,toxicity_endpoint,283,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
837,toxicity_endpoint,284,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
838,toxicity_endpoint,285,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
839,toxicity_endpoint,286,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
840,toxicity_endpoint,287,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for toxicity; location=PubMed abstract sentence 10.,2026-06-01T23:45:02+00:00
841,toxicity_endpoint,288,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
842,toxicity_endpoint,289,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
843,toxicity_endpoint,290,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
844,toxicity_endpoint,291,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
845,toxicity_endpoint,292,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
846,toxicity_endpoint,293,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
847,toxicity_endpoint,294,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
848,toxicity_endpoint,295,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
849,toxicity_endpoint,296,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
850,toxicity_endpoint,297,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
851,toxicity_endpoint,298,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
852,toxicity_endpoint,299,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
853,toxicity_endpoint,300,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
854,toxicity_endpoint,301,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
855,toxicity_endpoint,302,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
856,toxicity_endpoint,303,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
857,toxicity_endpoint,304,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
858,toxicity_endpoint,305,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
859,toxicity_endpoint,306,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
860,toxicity_endpoint,307,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
861,toxicity_endpoint,308,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
862,toxicity_endpoint,309,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
863,toxicity_endpoint,310,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
864,toxicity_endpoint,311,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
865,toxicity_endpoint,312,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
866,toxicity_endpoint,313,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
867,toxicity_endpoint,314,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
868,toxicity_endpoint,315,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
869,toxicity_endpoint,316,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for toxicity; location=PubMed abstract sentence 4.,2026-06-01T23:45:02+00:00
870,toxicity_endpoint,317,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for cell viability/cytotoxicity; location=PubMed abstract sentence 9.,2026-06-01T23:45:02+00:00
871,toxicity_endpoint,318,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for renal safety; location=PubMed abstract.,2026-06-01T23:45:02+00:00
872,toxicity_endpoint,319,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
873,toxicity_endpoint,320,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
874,toxicity_endpoint,321,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
875,toxicity_endpoint,322,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
876,toxicity_endpoint,323,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
877,toxicity_endpoint,324,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
878,toxicity_endpoint,325,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
879,toxicity_endpoint,326,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract sentence 5.,2026-06-01T23:45:02+00:00
880,toxicity_endpoint,327,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
881,toxicity_endpoint,328,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
882,toxicity_endpoint,329,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
883,toxicity_endpoint,330,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
884,toxicity_endpoint,331,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
885,toxicity_endpoint,332,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
886,toxicity_endpoint,333,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
887,toxicity_endpoint,334,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
888,toxicity_endpoint,335,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
889,toxicity_endpoint,336,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
890,toxicity_endpoint,337,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
891,toxicity_endpoint,338,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=PubMed abstract.,2026-06-01T23:45:02+00:00
892,toxicity_endpoint,339,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
893,toxicity_endpoint,340,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
894,toxicity_endpoint,341,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
895,toxicity_endpoint,342,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
896,toxicity_endpoint,343,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for DNA damage response; location=PubMed abstract sentence 2.,2026-06-01T23:45:02+00:00
897,toxicity_endpoint,344,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
898,toxicity_endpoint,345,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
899,toxicity_endpoint,346,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
900,toxicity_endpoint,347,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
901,toxicity_endpoint,348,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
902,toxicity_endpoint,349,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
903,toxicity_endpoint,350,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
904,toxicity_endpoint,351,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
905,toxicity_endpoint,352,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
906,toxicity_endpoint,353,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
907,toxicity_endpoint,354,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-01T23:45:02+00:00
908,toxicity_endpoint,355,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for renal safety; location=PubMed abstract.,2026-06-01T23:45:02+00:00
909,toxicity_endpoint,356,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for renal safety; location=PubMed abstract.,2026-06-01T23:45:02+00:00
910,offtarget_evidence,51,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for transcriptome-level off-target effect; location=PubMed abstract.,2026-06-01T23:45:02+00:00
911,curation_candidate,1512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
912,curation_candidate,1523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
913,curation_candidate,1691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: environmental/diagnostic toxicity assay, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
914,curation_candidate,1695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
915,curation_candidate,2392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
916,curation_candidate,2416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
917,curation_candidate,2904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
918,curation_candidate,4235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
919,curation_candidate,8818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
920,curation_candidate,9391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
921,curation_candidate,1706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
922,curation_candidate,1707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
923,curation_candidate,1709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
924,curation_candidate,1717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
925,curation_candidate,2469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
926,curation_candidate,716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
927,curation_candidate,1434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
928,curation_candidate,1725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
929,curation_candidate,8971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
930,curation_candidate,976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
931,curation_candidate,2535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
932,curation_candidate,2547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
933,curation_candidate,4436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
934,curation_candidate,2001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
935,curation_candidate,9528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
936,curation_candidate,1487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
937,curation_candidate,2594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
938,curation_candidate,2595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
939,curation_candidate,4515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
940,curation_candidate,1768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
941,curation_candidate,4552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
942,curation_candidate,2624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
943,curation_candidate,2631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
944,curation_candidate,3037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
945,curation_candidate,276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
946,curation_candidate,2146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
947,curation_candidate,6820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
948,curation_candidate,1882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
949,curation_candidate,2450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
950,curation_candidate,8847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
951,curation_candidate,4297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
952,curation_candidate,282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
953,curation_candidate,336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
954,curation_candidate,512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
955,curation_candidate,4664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
956,curation_candidate,4811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
957,curation_candidate,4925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
958,curation_candidate,5105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
959,curation_candidate,5123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
960,curation_candidate,5216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
961,curation_candidate,5404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
962,curation_candidate,5446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
963,curation_candidate,5469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
964,curation_candidate,5684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
965,curation_candidate,1640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
966,curation_candidate,1652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
967,curation_candidate,2211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
968,curation_candidate,3398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
969,curation_candidate,6282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
970,curation_candidate,6428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
971,curation_candidate,6637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
972,curation_candidate,6879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
973,curation_candidate,7181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
974,curation_candidate,7321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
975,curation_candidate,7402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
976,curation_candidate,7713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
977,curation_candidate,7790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
978,curation_candidate,1257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
979,curation_candidate,1276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
980,curation_candidate,1510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
981,curation_candidate,7919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
982,curation_candidate,8062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
983,curation_candidate,8405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
984,curation_candidate,10215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
985,curation_candidate,913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
986,curation_candidate,1364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
987,curation_candidate,1705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-01T23:45:02+00:00
988,curation_candidate,8753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
989,curation_candidate,8822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
990,curation_candidate,1038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
991,curation_candidate,8963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
992,curation_candidate,1731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
993,curation_candidate,1901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
994,curation_candidate,356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
995,curation_candidate,4975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
996,curation_candidate,5287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
997,curation_candidate,5305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
998,curation_candidate,397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
999,curation_candidate,827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1000,curation_candidate,1128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1001,curation_candidate,2221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1002,curation_candidate,3428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1003,curation_candidate,6267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1004,curation_candidate,6790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1005,curation_candidate,7334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1006,curation_candidate,19,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1007,curation_candidate,2269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1008,curation_candidate,4012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1009,curation_candidate,8370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1010,curation_candidate,704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1011,curation_candidate,8698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1012,curation_candidate,1410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1013,curation_candidate,1748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1014,curation_candidate,4966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1015,curation_candidate,256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1016,curation_candidate,985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1017,curation_candidate,997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1018,curation_candidate,1121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1019,curation_candidate,1448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1020,curation_candidate,2705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1021,curation_candidate,3221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1022,curation_candidate,4667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1023,curation_candidate,4741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1024,curation_candidate,4930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1025,curation_candidate,5094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1026,curation_candidate,5106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1027,curation_candidate,5144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1028,curation_candidate,5165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1029,curation_candidate,5176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1030,curation_candidate,5269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1031,curation_candidate,5436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1032,curation_candidate,5459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1033,curation_candidate,5614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1034,curation_candidate,416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1035,curation_candidate,480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1036,curation_candidate,483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1037,curation_candidate,1171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: commentary/correction, not primary evidence",2026-06-01T23:45:02+00:00
1038,curation_candidate,2119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1039,curation_candidate,2167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1040,curation_candidate,2732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1041,curation_candidate,2733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1042,curation_candidate,2742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1043,curation_candidate,2753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1044,curation_candidate,2760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1045,curation_candidate,3370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1046,curation_candidate,3795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1047,curation_candidate,3892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1048,curation_candidate,3906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1049,curation_candidate,6066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1050,curation_candidate,6143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
1051,curation_candidate,6150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1052,curation_candidate,6379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1053,curation_candidate,6451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1054,curation_candidate,6673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1055,curation_candidate,6735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1056,curation_candidate,6750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1057,curation_candidate,6858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1058,curation_candidate,6890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1059,curation_candidate,7266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1060,curation_candidate,7337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1061,curation_candidate,9053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1062,curation_candidate,9062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1063,curation_candidate,9727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1064,curation_candidate,9828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1065,curation_candidate,9978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1066,curation_candidate,487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1067,curation_candidate,1035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1068,curation_candidate,1975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1069,curation_candidate,2828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1070,curation_candidate,2829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1071,curation_candidate,2835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1072,curation_candidate,2863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1073,curation_candidate,2869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1074,curation_candidate,2874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1075,curation_candidate,3991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1076,curation_candidate,7927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1077,curation_candidate,7972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1078,curation_candidate,8044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1079,curation_candidate,8149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1080,curation_candidate,8183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1081,curation_candidate,8379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1082,curation_candidate,8507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1083,curation_candidate,8518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1084,curation_candidate,9075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1085,curation_candidate,9289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1086,curation_candidate,10062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1087,curation_candidate,10071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1088,curation_candidate,10180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
1089,curation_candidate,10198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1090,curation_candidate,2422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1091,curation_candidate,2888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1092,curation_candidate,2914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1093,curation_candidate,4254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1094,curation_candidate,10286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1095,curation_candidate,1789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1096,curation_candidate,2933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-01T23:45:02+00:00
1097,curation_candidate,2944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1098,curation_candidate,2949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1099,curation_candidate,2951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: physicochemical/fluorescence assay, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1100,curation_candidate,4301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1101,curation_candidate,1529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1102,curation_candidate,1990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1103,curation_candidate,2507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1104,curation_candidate,2963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1105,curation_candidate,2964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1106,curation_candidate,8872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1107,curation_candidate,9446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1108,curation_candidate,3000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1109,curation_candidate,3005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1110,curation_candidate,3006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1111,curation_candidate,3015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1112,curation_candidate,9118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1113,curation_candidate,9125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1114,curation_candidate,2567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1115,curation_candidate,9529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1116,curation_candidate,9566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1117,curation_candidate,9568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1118,curation_candidate,9613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1119,curation_candidate,4534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1120,curation_candidate,59,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: commentary/correction, not primary evidence",2026-06-01T23:45:02+00:00
1121,curation_candidate,370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1122,curation_candidate,983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1123,curation_candidate,988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1124,curation_candidate,1002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1125,curation_candidate,1005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1126,curation_candidate,1102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1127,curation_candidate,2014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1128,curation_candidate,2029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1129,curation_candidate,2032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1130,curation_candidate,2077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1131,curation_candidate,2650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1132,curation_candidate,2654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1133,curation_candidate,2663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1134,curation_candidate,2697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1135,curation_candidate,3151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1136,curation_candidate,3192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1137,curation_candidate,4727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1138,curation_candidate,4770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1139,curation_candidate,4862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1140,curation_candidate,5082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1141,curation_candidate,5089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1142,curation_candidate,5166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1143,curation_candidate,5620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1144,curation_candidate,5754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-01T23:45:02+00:00
1145,curation_candidate,5841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1146,curation_candidate,9700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1147,curation_candidate,131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1148,curation_candidate,229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1149,curation_candidate,232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1150,curation_candidate,2127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1151,curation_candidate,2240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1152,curation_candidate,2713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1153,curation_candidate,2724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1154,curation_candidate,2778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1155,curation_candidate,2798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1156,curation_candidate,3445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1157,curation_candidate,3594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1158,curation_candidate,6250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1159,curation_candidate,6404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1160,curation_candidate,6672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1161,curation_candidate,6765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1162,curation_candidate,6818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1163,curation_candidate,7051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1164,curation_candidate,7188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1165,curation_candidate,7452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1166,curation_candidate,7470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1167,curation_candidate,7510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1168,curation_candidate,7766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1169,curation_candidate,8885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1170,curation_candidate,9038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1171,curation_candidate,9060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1172,curation_candidate,9203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1173,curation_candidate,9715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1174,curation_candidate,9835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1175,curation_candidate,9973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1176,curation_candidate,877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1177,curation_candidate,1977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-01T23:45:02+00:00
1178,curation_candidate,2293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1179,curation_candidate,2305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1180,curation_candidate,2814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1181,curation_candidate,2837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1182,curation_candidate,2862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1183,curation_candidate,4026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1184,curation_candidate,4032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1185,curation_candidate,7910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1186,curation_candidate,7947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1187,curation_candidate,8367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1188,curation_candidate,8493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1189,curation_candidate,8770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1190,curation_candidate,8912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1191,curation_candidate,9077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1192,curation_candidate,490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1193,curation_candidate,1698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1194,curation_candidate,4189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1195,curation_candidate,4250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1196,curation_candidate,8650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1197,curation_candidate,8661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1198,curation_candidate,8670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1199,curation_candidate,8672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1200,curation_candidate,8730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1201,curation_candidate,10256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1202,curation_candidate,936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1203,curation_candidate,941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1204,curation_candidate,1387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1205,curation_candidate,1513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-01T23:45:02+00:00
1206,curation_candidate,4348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1207,curation_candidate,8871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1208,curation_candidate,1993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1209,curation_candidate,2517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1210,curation_candidate,2962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1211,curation_candidate,4394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1212,curation_candidate,4432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1213,curation_candidate,8969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1214,curation_candidate,2529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1215,curation_candidate,1905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1216,curation_candidate,1942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1217,curation_candidate,2617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1218,curation_candidate,3034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1219,curation_candidate,5582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1220,curation_candidate,1858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1221,curation_candidate,2249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1222,curation_candidate,6946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1223,curation_candidate,919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1224,curation_candidate,8849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1225,curation_candidate,514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1226,curation_candidate,2646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1227,curation_candidate,3088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1228,curation_candidate,3161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1229,curation_candidate,3292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1230,curation_candidate,4812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1231,curation_candidate,5169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1232,curation_candidate,5334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-01T23:45:02+00:00
1233,curation_candidate,5616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1234,curation_candidate,9667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1235,curation_candidate,314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1236,curation_candidate,1835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1237,curation_candidate,1842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1238,curation_candidate,2706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1239,curation_candidate,2746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1240,curation_candidate,3417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1241,curation_candidate,6168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-01T23:45:02+00:00
1242,curation_candidate,6431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1243,curation_candidate,9791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1244,curation_candidate,9881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1245,curation_candidate,10122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1246,curation_candidate,10259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1247,curation_candidate,2940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1248,curation_candidate,4379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1249,curation_candidate,4395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: physicochemical/fluorescence assay, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1250,curation_candidate,8854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1251,curation_candidate,6461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1252,curation_candidate,4063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1253,curation_candidate,8570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1254,curation_candidate,8937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1255,curation_candidate,606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1256,curation_candidate,727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1257,curation_candidate,2645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1258,curation_candidate,3137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1259,curation_candidate,4654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1260,curation_candidate,4726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1261,curation_candidate,4869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1262,curation_candidate,4883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1263,curation_candidate,4936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1264,curation_candidate,5044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1265,curation_candidate,5264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1266,curation_candidate,5301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1267,curation_candidate,5304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1268,curation_candidate,5363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1269,curation_candidate,5490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1270,curation_candidate,5541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1271,curation_candidate,5563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1272,curation_candidate,5565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1273,curation_candidate,5636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1274,curation_candidate,5642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1275,curation_candidate,1154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1276,curation_candidate,2203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1277,curation_candidate,2805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1278,curation_candidate,3403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1279,curation_candidate,6161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1280,curation_candidate,6178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1281,curation_candidate,6223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1282,curation_candidate,6383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1283,curation_candidate,6385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1284,curation_candidate,6533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1285,curation_candidate,6709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1286,curation_candidate,6713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1287,curation_candidate,6822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1288,curation_candidate,7354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1289,curation_candidate,7529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1290,curation_candidate,7542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1291,curation_candidate,7655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1292,curation_candidate,7763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1293,curation_candidate,7806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1294,curation_candidate,1250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1295,curation_candidate,2819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1296,curation_candidate,4064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1297,curation_candidate,9365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1298,curation_candidate,10053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1299,curation_candidate,2433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1300,curation_candidate,2927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1301,curation_candidate,8681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1302,curation_candidate,8708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1303,curation_candidate,8955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1304,curation_candidate,2487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1305,curation_candidate,4289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1306,curation_candidate,1429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1307,curation_candidate,1996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1308,curation_candidate,1730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1309,curation_candidate,586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1310,curation_candidate,3119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1311,curation_candidate,3157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1312,curation_candidate,3252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1313,curation_candidate,5398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1314,curation_candidate,5419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1315,curation_candidate,40,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1316,curation_candidate,1138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1317,curation_candidate,1844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1318,curation_candidate,3521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1319,curation_candidate,6215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1320,curation_candidate,6544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1321,curation_candidate,6724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1322,curation_candidate,2275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1323,curation_candidate,7898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1324,curation_candidate,10207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1325,curation_candidate,8936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1326,curation_candidate,10275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1327,curation_candidate,10282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-01T23:45:02+00:00
1328,curation_candidate,311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1329,curation_candidate,459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1330,curation_candidate,2683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1331,curation_candidate,5950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1332,curation_candidate,6,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1333,curation_candidate,29,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1334,curation_candidate,852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1335,curation_candidate,1014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1336,curation_candidate,1782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1337,curation_candidate,1861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1338,curation_candidate,7249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1339,curation_candidate,1891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1340,curation_candidate,1579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1341,curation_candidate,9443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: physicochemical/fluorescence assay, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1342,curation_candidate,3019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1343,curation_candidate,9119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1344,curation_candidate,89,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1345,curation_candidate,92,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1346,curation_candidate,110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1347,curation_candidate,125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1348,curation_candidate,204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1349,curation_candidate,214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1350,curation_candidate,216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1351,curation_candidate,217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1352,curation_candidate,218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
1353,curation_candidate,220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1354,curation_candidate,221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1355,curation_candidate,224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1356,curation_candidate,305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1357,curation_candidate,332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1358,curation_candidate,352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1359,curation_candidate,457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1360,curation_candidate,458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1361,curation_candidate,492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1362,curation_candidate,495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1363,curation_candidate,539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1364,curation_candidate,562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1365,curation_candidate,574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1366,curation_candidate,584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1367,curation_candidate,588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1368,curation_candidate,626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1369,curation_candidate,663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1370,curation_candidate,666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1371,curation_candidate,668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1372,curation_candidate,669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1373,curation_candidate,672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1374,curation_candidate,786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1375,curation_candidate,800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1376,curation_candidate,804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1377,curation_candidate,806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1378,curation_candidate,810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1379,curation_candidate,1494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1380,curation_candidate,1589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1381,curation_candidate,1591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1382,curation_candidate,1594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1383,curation_candidate,1595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1384,curation_candidate,1596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1385,curation_candidate,1597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1386,curation_candidate,1599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
1387,curation_candidate,1602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1388,curation_candidate,1604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1389,curation_candidate,1607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1390,curation_candidate,1610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1391,curation_candidate,1781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1392,curation_candidate,2652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1393,curation_candidate,3081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1394,curation_candidate,3091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1395,curation_candidate,3102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1396,curation_candidate,3210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1397,curation_candidate,3232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1398,curation_candidate,3298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1399,curation_candidate,3341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1400,curation_candidate,4631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1401,curation_candidate,4634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1402,curation_candidate,4636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1403,curation_candidate,4788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1404,curation_candidate,4985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1405,curation_candidate,4987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1406,curation_candidate,5001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1407,curation_candidate,5137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1408,curation_candidate,5145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1409,curation_candidate,5158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1410,curation_candidate,5203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1411,curation_candidate,5265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1412,curation_candidate,5332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1413,curation_candidate,5387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1414,curation_candidate,5394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1415,curation_candidate,5648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1416,curation_candidate,5654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1417,curation_candidate,5658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1418,curation_candidate,5727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1419,curation_candidate,5792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1420,curation_candidate,5803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1421,curation_candidate,5846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1422,curation_candidate,5849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1423,curation_candidate,5862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1424,curation_candidate,5882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1425,curation_candidate,5894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1426,curation_candidate,5915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1427,curation_candidate,5927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1428,curation_candidate,5929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1429,curation_candidate,6044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1430,curation_candidate,8879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1431,curation_candidate,205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1432,curation_candidate,259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1433,curation_candidate,263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: physicochemical/fluorescence assay, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1434,curation_candidate,426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1435,curation_candidate,646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1436,curation_candidate,675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1437,curation_candidate,680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1438,curation_candidate,681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1439,curation_candidate,682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1440,curation_candidate,684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1441,curation_candidate,689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1442,curation_candidate,820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1443,curation_candidate,1019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1444,curation_candidate,1185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1445,curation_candidate,1210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1446,curation_candidate,1502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1447,curation_candidate,1546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1448,curation_candidate,1547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1449,curation_candidate,1613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1450,curation_candidate,1620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1451,curation_candidate,1624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1452,curation_candidate,1626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1453,curation_candidate,1628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1454,curation_candidate,1630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1455,curation_candidate,1631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1456,curation_candidate,1634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1457,curation_candidate,1645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1458,curation_candidate,1655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1459,curation_candidate,1661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1460,curation_candidate,1662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1461,curation_candidate,1663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1462,curation_candidate,1665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1463,curation_candidate,1853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1464,curation_candidate,2136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1465,curation_candidate,2137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-01T23:45:02+00:00
1466,curation_candidate,2150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1467,curation_candidate,2175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1468,curation_candidate,2192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1469,curation_candidate,2231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1470,curation_candidate,2738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1471,curation_candidate,2740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1472,curation_candidate,3436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1473,curation_candidate,3483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1474,curation_candidate,3497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1475,curation_candidate,3514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-01T23:45:02+00:00
1476,curation_candidate,3517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1477,curation_candidate,3548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1478,curation_candidate,3609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1479,curation_candidate,3668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1480,curation_candidate,3704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1481,curation_candidate,3736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1482,curation_candidate,3853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1483,curation_candidate,3883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1484,curation_candidate,6157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1485,curation_candidate,6417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1486,curation_candidate,6450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1487,curation_candidate,6459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1488,curation_candidate,6479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1489,curation_candidate,6512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1490,curation_candidate,6579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1491,curation_candidate,6590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1492,curation_candidate,6617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1493,curation_candidate,6675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1494,curation_candidate,6739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1495,curation_candidate,6752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1496,curation_candidate,6806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1497,curation_candidate,6842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1498,curation_candidate,6845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1499,curation_candidate,6896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1500,curation_candidate,7075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1501,curation_candidate,7103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1502,curation_candidate,7131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1503,curation_candidate,7137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1504,curation_candidate,7194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1505,curation_candidate,7202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1506,curation_candidate,7225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1507,curation_candidate,7279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1508,curation_candidate,7282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1509,curation_candidate,7294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1510,curation_candidate,7351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1511,curation_candidate,7365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1512,curation_candidate,7427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1513,curation_candidate,7439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1514,curation_candidate,7533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1515,curation_candidate,7548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1516,curation_candidate,7570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1517,curation_candidate,7603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1518,curation_candidate,7620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1519,curation_candidate,7682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1520,curation_candidate,7725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1521,curation_candidate,7727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1522,curation_candidate,7849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1523,curation_candidate,8764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1524,curation_candidate,8765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1525,curation_candidate,8766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1526,curation_candidate,8767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1527,curation_candidate,8798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1528,curation_candidate,8799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1529,curation_candidate,8800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1530,curation_candidate,8806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1531,curation_candidate,8807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-01T23:45:02+00:00
1532,curation_candidate,8881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1533,curation_candidate,8898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1534,curation_candidate,9182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1535,curation_candidate,9259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1536,curation_candidate,9975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1537,curation_candidate,10039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
1538,curation_candidate,21,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1539,curation_candidate,42,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1540,curation_candidate,194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1541,curation_candidate,198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1542,curation_candidate,696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1543,curation_candidate,872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1544,curation_candidate,886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1545,curation_candidate,1032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1546,curation_candidate,1034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1547,curation_candidate,1266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1548,curation_candidate,1287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1549,curation_candidate,1310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1550,curation_candidate,1324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1551,curation_candidate,1326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1552,curation_candidate,1511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1553,curation_candidate,1674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1554,curation_candidate,1677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1555,curation_candidate,1678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1556,curation_candidate,1680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1557,curation_candidate,1682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1558,curation_candidate,1684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1559,curation_candidate,1685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1560,curation_candidate,1688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1561,curation_candidate,1867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1562,curation_candidate,1972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1563,curation_candidate,2263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1564,curation_candidate,2271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1565,curation_candidate,2311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1566,curation_candidate,2323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1567,curation_candidate,2367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1568,curation_candidate,2843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1569,curation_candidate,2879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1570,curation_candidate,3998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1571,curation_candidate,4045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1572,curation_candidate,4054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1573,curation_candidate,4138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1574,curation_candidate,7938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1575,curation_candidate,7941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1576,curation_candidate,8000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1577,curation_candidate,8077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1578,curation_candidate,8096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1579,curation_candidate,8112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1580,curation_candidate,8122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1581,curation_candidate,8132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1582,curation_candidate,8292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1583,curation_candidate,8318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1584,curation_candidate,8360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1585,curation_candidate,8417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1586,curation_candidate,8437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1587,curation_candidate,8454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: chemotherapy co-delivery/efficacy study, not oligo safety evidence",2026-06-01T23:45:02+00:00
1588,curation_candidate,8509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1589,curation_candidate,8513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1590,curation_candidate,8537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1591,curation_candidate,8790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1592,curation_candidate,8808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1593,curation_candidate,8809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
1594,curation_candidate,8812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1595,curation_candidate,8814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1596,curation_candidate,8815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1597,curation_candidate,8835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1598,curation_candidate,8842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1599,curation_candidate,8924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: mixed SMA therapy safety is not oligo-specific,2026-06-01T23:45:02+00:00
1600,curation_candidate,8925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1601,curation_candidate,9279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1602,curation_candidate,9309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1603,curation_candidate,9331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1604,curation_candidate,9352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1605,curation_candidate,9367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1606,curation_candidate,10200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-01T23:45:02+00:00
1607,curation_candidate,10234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1608,curation_candidate,632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1609,curation_candidate,723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1610,curation_candidate,911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: mixed SMA therapy safety is not oligo-specific,2026-06-01T23:45:02+00:00
1611,curation_candidate,923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1612,curation_candidate,927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1613,curation_candidate,929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1614,curation_candidate,1342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1615,curation_candidate,1369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1616,curation_candidate,1689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1617,curation_candidate,1699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1618,curation_candidate,2376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1619,curation_candidate,2405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1620,curation_candidate,2415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1621,curation_candidate,2417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1622,curation_candidate,2421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1623,curation_candidate,2908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1624,curation_candidate,4199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1625,curation_candidate,8621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1626,curation_candidate,8624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1627,curation_candidate,8726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1628,curation_candidate,8755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1629,curation_candidate,8820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1630,curation_candidate,8821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1631,curation_candidate,8931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1632,curation_candidate,9413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1633,curation_candidate,10306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1634,curation_candidate,708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1635,curation_candidate,752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1636,curation_candidate,778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1637,curation_candidate,931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1638,curation_candidate,950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1639,curation_candidate,1394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-01T23:45:02+00:00
1640,curation_candidate,1575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1641,curation_candidate,1712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-01T23:45:02+00:00
1642,curation_candidate,1714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1643,curation_candidate,1715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1644,curation_candidate,1716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1645,curation_candidate,1720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1646,curation_candidate,2472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1647,curation_candidate,4306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1648,curation_candidate,4346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1649,curation_candidate,8824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1650,curation_candidate,9422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1651,curation_candidate,711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1652,curation_candidate,1042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1653,curation_candidate,1532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1654,curation_candidate,1723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-01T23:45:02+00:00
1655,curation_candidate,1724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1656,curation_candidate,2519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1657,curation_candidate,2979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1658,curation_candidate,4406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1659,curation_candidate,4412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1660,curation_candidate,4421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1661,curation_candidate,8853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1662,curation_candidate,717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1663,curation_candidate,1736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1664,curation_candidate,1738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1665,curation_candidate,1798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-01T23:45:02+00:00
1666,curation_candidate,2536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1667,curation_candidate,2548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1668,curation_candidate,2549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1669,curation_candidate,4457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1670,curation_candidate,4462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1671,curation_candidate,4466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1672,curation_candidate,9477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-01T23:45:02+00:00
1673,curation_candidate,4472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1674,curation_candidate,8776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-01T23:45:02+00:00
1675,curation_candidate,8982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1676,curation_candidate,2577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-01T23:45:02+00:00
1677,curation_candidate,1533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1678,curation_candidate,1758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1679,curation_candidate,1763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-01T23:45:02+00:00
1680,curation_candidate,8791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1681,curation_candidate,1766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-01T23:45:02+00:00
1682,curation_candidate,4521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1683,curation_candidate,4539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1684,curation_candidate,1518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-01T23:45:02+00:00
1685,curation_candidate,1773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1686,curation_candidate,1774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1687,curation_candidate,1934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1688,curation_candidate,4547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-01T23:45:02+00:00
1689,curation_candidate,1775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-01T23:45:02+00:00
1690,curation_candidate,1521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-01T23:45:02+00:00
1691,curation_candidate,306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-01T23:45:02+00:00
1692,toxicity_endpoint,357,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1693,toxicity_endpoint,358,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1694,toxicity_endpoint,359,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1695,toxicity_endpoint,360,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1696,toxicity_endpoint,361,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1697,toxicity_endpoint,362,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1698,toxicity_endpoint,363,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1699,toxicity_endpoint,364,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1700,toxicity_endpoint,365,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1701,toxicity_endpoint,366,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1702,toxicity_endpoint,367,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1703,toxicity_endpoint,368,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1704,toxicity_endpoint,369,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1705,toxicity_endpoint,370,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1706,toxicity_endpoint,371,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1707,toxicity_endpoint,372,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1708,toxicity_endpoint,373,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1709,toxicity_endpoint,374,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1710,toxicity_endpoint,375,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1711,toxicity_endpoint,376,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1712,toxicity_endpoint,377,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1713,toxicity_endpoint,378,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1714,toxicity_endpoint,379,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1715,toxicity_endpoint,380,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1716,toxicity_endpoint,381,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1717,toxicity_endpoint,382,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1718,toxicity_endpoint,383,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1719,toxicity_endpoint,384,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1720,toxicity_endpoint,385,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1721,toxicity_endpoint,386,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1722,toxicity_endpoint,387,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1723,toxicity_endpoint,388,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1724,toxicity_endpoint,389,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1725,toxicity_endpoint,390,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1726,toxicity_endpoint,391,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1727,toxicity_endpoint,392,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1728,toxicity_endpoint,393,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1729,toxicity_endpoint,394,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1730,toxicity_endpoint,395,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1731,toxicity_endpoint,396,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for safety/tolerability; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1732,toxicity_endpoint,397,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for thrombocytopenia; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1733,toxicity_endpoint,398,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1734,toxicity_endpoint,399,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1735,toxicity_endpoint,400,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1736,toxicity_endpoint,401,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1737,toxicity_endpoint,402,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1738,toxicity_endpoint,403,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1739,toxicity_endpoint,404,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for thrombocytopenia; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1740,toxicity_endpoint,405,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1741,toxicity_endpoint,406,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1742,toxicity_endpoint,407,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for thrombocytopenia; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1743,toxicity_endpoint,408,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1744,toxicity_endpoint,409,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1745,toxicity_endpoint,410,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for renal safety; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1746,toxicity_endpoint,411,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1747,toxicity_endpoint,412,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for hepatotoxicity; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1748,toxicity_endpoint,413,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide toxicity evidence for renal safety; location=PubMed abstract.,2026-06-02T12:33:40+00:00
1749,curation_candidate,54,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:40+00:00
1750,curation_candidate,64,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:40+00:00
1751,curation_candidate,72,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:40+00:00
1752,curation_candidate,86,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:40+00:00
1753,curation_candidate,107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1754,curation_candidate,223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1755,curation_candidate,308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1756,curation_candidate,377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
1757,curation_candidate,379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:40+00:00
1758,curation_candidate,464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1759,curation_candidate,468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1760,curation_candidate,469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1761,curation_candidate,471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-02T12:33:40+00:00
1762,curation_candidate,478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1763,curation_candidate,499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1764,curation_candidate,599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1765,curation_candidate,660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1766,curation_candidate,807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1767,curation_candidate,813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1768,curation_candidate,982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1769,curation_candidate,992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-02T12:33:40+00:00
1770,curation_candidate,998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1771,curation_candidate,1000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1772,curation_candidate,1009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1773,curation_candidate,1063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1774,curation_candidate,1109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1775,curation_candidate,1113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1776,curation_candidate,1451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1777,curation_candidate,1535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1778,curation_candidate,1593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1779,curation_candidate,1598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1780,curation_candidate,1609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1781,curation_candidate,1611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1782,curation_candidate,1779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1783,curation_candidate,1831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1784,curation_candidate,1833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1785,curation_candidate,1947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1786,curation_candidate,1949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1787,curation_candidate,2018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1788,curation_candidate,2026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1789,curation_candidate,2030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1790,curation_candidate,2033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1791,curation_candidate,2035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1792,curation_candidate,2046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1793,curation_candidate,2047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1794,curation_candidate,2048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1795,curation_candidate,2053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1796,curation_candidate,2054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1797,curation_candidate,2057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1798,curation_candidate,2061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1799,curation_candidate,2071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1800,curation_candidate,2084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1801,curation_candidate,2087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
1802,curation_candidate,2090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1803,curation_candidate,2092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1804,curation_candidate,2094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1805,curation_candidate,2634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1806,curation_candidate,2635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1807,curation_candidate,2636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:40+00:00
1808,curation_candidate,2640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1809,curation_candidate,2641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1810,curation_candidate,2642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1811,curation_candidate,2647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1812,curation_candidate,2648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1813,curation_candidate,2649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1814,curation_candidate,2655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1815,curation_candidate,2669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1816,curation_candidate,2670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1817,curation_candidate,2671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1818,curation_candidate,2672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1819,curation_candidate,2686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1820,curation_candidate,2692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1821,curation_candidate,2693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1822,curation_candidate,2695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1823,curation_candidate,2696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1824,curation_candidate,2699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1825,curation_candidate,2702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1826,curation_candidate,3071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1827,curation_candidate,3154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1828,curation_candidate,3173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1829,curation_candidate,3237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1830,curation_candidate,3271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1831,curation_candidate,3280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1832,curation_candidate,3319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1833,curation_candidate,4642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1834,curation_candidate,4650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1835,curation_candidate,4696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1836,curation_candidate,4699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:40+00:00
1837,curation_candidate,4710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1838,curation_candidate,4719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1839,curation_candidate,4735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1840,curation_candidate,4743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1841,curation_candidate,4744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1842,curation_candidate,4768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:40+00:00
1843,curation_candidate,4790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1844,curation_candidate,4816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1845,curation_candidate,4837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1846,curation_candidate,4848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1847,curation_candidate,4891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:40+00:00
1848,curation_candidate,4918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1849,curation_candidate,4923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1850,curation_candidate,4943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
1851,curation_candidate,4960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1852,curation_candidate,5015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1853,curation_candidate,5016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1854,curation_candidate,5151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1855,curation_candidate,5159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1856,curation_candidate,5186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1857,curation_candidate,5196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1858,curation_candidate,5212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1859,curation_candidate,5227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1860,curation_candidate,5250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1861,curation_candidate,5278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1862,curation_candidate,5298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1863,curation_candidate,5395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-02T12:33:40+00:00
1864,curation_candidate,5411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1865,curation_candidate,5424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1866,curation_candidate,5428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-02T12:33:40+00:00
1867,curation_candidate,5430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1868,curation_candidate,5439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1869,curation_candidate,5471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1870,curation_candidate,5538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1871,curation_candidate,5577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1872,curation_candidate,5595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1873,curation_candidate,5602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1874,curation_candidate,5659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1875,curation_candidate,5705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:40+00:00
1876,curation_candidate,5722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1877,curation_candidate,5743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1878,curation_candidate,5747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
1879,curation_candidate,5781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1880,curation_candidate,5817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1881,curation_candidate,5868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1882,curation_candidate,5876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1883,curation_candidate,5910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1884,curation_candidate,5913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1885,curation_candidate,5918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1886,curation_candidate,5944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1887,curation_candidate,5978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1888,curation_candidate,5983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1889,curation_candidate,5986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-02T12:33:40+00:00
1890,curation_candidate,6017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1891,curation_candidate,8796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1892,curation_candidate,9151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1893,curation_candidate,9673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1894,curation_candidate,9679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1895,curation_candidate,9714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:40+00:00
1896,curation_candidate,5,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1897,curation_candidate,412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1898,curation_candidate,482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1899,curation_candidate,485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1900,curation_candidate,833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:40+00:00
1901,curation_candidate,1013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
1902,curation_candidate,1022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1903,curation_candidate,1166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1904,curation_candidate,1212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1905,curation_candidate,1242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1906,curation_candidate,1246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1907,curation_candidate,1495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
1908,curation_candidate,1497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:40+00:00
1909,curation_candidate,1505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1910,curation_candidate,1545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1911,curation_candidate,1666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1912,curation_candidate,1670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1913,curation_candidate,1843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1914,curation_candidate,1957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1915,curation_candidate,1961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1916,curation_candidate,1963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1917,curation_candidate,2126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
1918,curation_candidate,2144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:40+00:00
1919,curation_candidate,2191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1920,curation_candidate,2200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1921,curation_candidate,2201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1922,curation_candidate,2209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1923,curation_candidate,2229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1924,curation_candidate,2250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1925,curation_candidate,2254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1926,curation_candidate,2258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1927,curation_candidate,2262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1928,curation_candidate,2716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1929,curation_candidate,2719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1930,curation_candidate,2725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1931,curation_candidate,2728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1932,curation_candidate,2737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:40+00:00
1933,curation_candidate,2744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1934,curation_candidate,2748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1935,curation_candidate,2755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1936,curation_candidate,2767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1937,curation_candidate,2774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1938,curation_candidate,2775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1939,curation_candidate,2780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1940,curation_candidate,2787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1941,curation_candidate,2807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1942,curation_candidate,3416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1943,curation_candidate,3529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1944,curation_candidate,3560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1945,curation_candidate,3565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1946,curation_candidate,3581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1947,curation_candidate,3663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1948,curation_candidate,3700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1949,curation_candidate,3843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1950,curation_candidate,3887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1951,curation_candidate,3919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1952,curation_candidate,3929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1953,curation_candidate,3949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1954,curation_candidate,3959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1955,curation_candidate,6130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1956,curation_candidate,6175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1957,curation_candidate,6278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1958,curation_candidate,6313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1959,curation_candidate,6359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1960,curation_candidate,6425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1961,curation_candidate,6443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1962,curation_candidate,6444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1963,curation_candidate,6472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1964,curation_candidate,6605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
1965,curation_candidate,6611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1966,curation_candidate,6624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1967,curation_candidate,6629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1968,curation_candidate,6677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1969,curation_candidate,6704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1970,curation_candidate,6706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1971,curation_candidate,6736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1972,curation_candidate,6757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1973,curation_candidate,6764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1974,curation_candidate,6780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1975,curation_candidate,6785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1976,curation_candidate,6794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1977,curation_candidate,6804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1978,curation_candidate,6836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1979,curation_candidate,6840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
1980,curation_candidate,6843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1981,curation_candidate,6870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1982,curation_candidate,6899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1983,curation_candidate,6953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1984,curation_candidate,6954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
1985,curation_candidate,6964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1986,curation_candidate,7015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1987,curation_candidate,7080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1988,curation_candidate,7164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1989,curation_candidate,7204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1990,curation_candidate,7227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
1991,curation_candidate,7268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1992,curation_candidate,7284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
1993,curation_candidate,7291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1994,curation_candidate,7295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:40+00:00
1995,curation_candidate,7306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1996,curation_candidate,7341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
1997,curation_candidate,7342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
1998,curation_candidate,7361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
1999,curation_candidate,7499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2000,curation_candidate,7522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2001,curation_candidate,7574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2002,curation_candidate,7601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2003,curation_candidate,7648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2004,curation_candidate,7667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2005,curation_candidate,7670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2006,curation_candidate,7676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2007,curation_candidate,7677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2008,curation_candidate,7720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2009,curation_candidate,7787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2010,curation_candidate,7798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2011,curation_candidate,7808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2012,curation_candidate,7872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2013,curation_candidate,8781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2014,curation_candidate,8884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2015,curation_candidate,8891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2016,curation_candidate,8896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2017,curation_candidate,8899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2018,curation_candidate,8902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2019,curation_candidate,8905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2020,curation_candidate,8906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2021,curation_candidate,8907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:40+00:00
2022,curation_candidate,9037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2023,curation_candidate,9039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2024,curation_candidate,9047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2025,curation_candidate,9057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2026,curation_candidate,9176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2027,curation_candidate,9206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2028,curation_candidate,9218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:40+00:00
2029,curation_candidate,9221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2030,curation_candidate,9232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:40+00:00
2031,curation_candidate,9237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:40+00:00
2032,curation_candidate,9782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2033,curation_candidate,9806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2034,curation_candidate,9860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:40+00:00
2035,curation_candidate,445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2036,curation_candidate,628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2037,curation_candidate,690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2038,curation_candidate,721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2039,curation_candidate,888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2040,curation_candidate,891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2041,curation_candidate,898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2042,curation_candidate,901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2043,curation_candidate,1031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2044,curation_candidate,1253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2045,curation_candidate,1269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2046,curation_candidate,1671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2047,curation_candidate,1676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2048,curation_candidate,1783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2049,curation_candidate,1970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2050,curation_candidate,2282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2051,curation_candidate,2285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2052,curation_candidate,2287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2053,curation_candidate,2308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:40+00:00
2054,curation_candidate,2315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2055,curation_candidate,2317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2056,curation_candidate,2320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:40+00:00
2057,curation_candidate,2343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2058,curation_candidate,2360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2059,curation_candidate,2373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2060,curation_candidate,2839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2061,curation_candidate,2847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2062,curation_candidate,2848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2063,curation_candidate,2849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2064,curation_candidate,2851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2065,curation_candidate,2857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2066,curation_candidate,2871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2067,curation_candidate,3980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2068,curation_candidate,3996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2069,curation_candidate,4028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:40+00:00
2070,curation_candidate,4044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2071,curation_candidate,4090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2072,curation_candidate,4103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2073,curation_candidate,4154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2074,curation_candidate,4172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2075,curation_candidate,7954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2076,curation_candidate,7961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2077,curation_candidate,8025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2078,curation_candidate,8029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2079,curation_candidate,8030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2080,curation_candidate,8035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2081,curation_candidate,8053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2082,curation_candidate,8139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2083,curation_candidate,8181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:40+00:00
2084,curation_candidate,8211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2085,curation_candidate,8221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2086,curation_candidate,8265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2087,curation_candidate,8277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-02T12:33:40+00:00
2088,curation_candidate,8316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2089,curation_candidate,8324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2090,curation_candidate,8350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2091,curation_candidate,8356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2092,curation_candidate,8365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2093,curation_candidate,8402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2094,curation_candidate,8467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2095,curation_candidate,8475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2096,curation_candidate,8550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2097,curation_candidate,8561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2098,curation_candidate,8566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2099,curation_candidate,8816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2100,curation_candidate,8837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2101,curation_candidate,8864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
2102,curation_candidate,8914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2103,curation_candidate,8927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2104,curation_candidate,8929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2105,curation_candidate,9086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2106,curation_candidate,9088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2107,curation_candidate,9089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2108,curation_candidate,9294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2109,curation_candidate,9373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2110,curation_candidate,916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2111,curation_candidate,1348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:40+00:00
2112,curation_candidate,1878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2113,curation_candidate,2377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: commentary/correction, not primary evidence",2026-06-02T12:33:40+00:00
2114,curation_candidate,2381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2115,curation_candidate,2388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2116,curation_candidate,2397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2117,curation_candidate,2404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2118,curation_candidate,2460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2119,curation_candidate,2894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2120,curation_candidate,2911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:40+00:00
2121,curation_candidate,4197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2122,curation_candidate,4279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:40+00:00
2123,curation_candidate,8582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2124,curation_candidate,8602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2125,curation_candidate,8637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2126,curation_candidate,8656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2127,curation_candidate,8704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2128,curation_candidate,8706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:40+00:00
2129,curation_candidate,8759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2130,curation_candidate,8774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2131,curation_candidate,8932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2132,curation_candidate,8935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2133,curation_candidate,8943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2134,curation_candidate,8948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2135,curation_candidate,8950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2136,curation_candidate,8958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2137,curation_candidate,9092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2138,curation_candidate,9388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2139,curation_candidate,10261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2140,curation_candidate,10263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2141,curation_candidate,10296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2142,curation_candidate,1039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2143,curation_candidate,1713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:40+00:00
2144,curation_candidate,1980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2145,curation_candidate,2482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:40+00:00
2146,curation_candidate,2485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:40+00:00
2147,curation_candidate,2489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2148,curation_candidate,2496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2149,curation_candidate,2931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2150,curation_candidate,2956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2151,curation_candidate,8968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-02T12:33:40+00:00
2152,curation_candidate,1412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2153,curation_candidate,1414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2154,curation_candidate,2497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2155,curation_candidate,2515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2156,curation_candidate,2525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2157,curation_candidate,4382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2158,curation_candidate,4422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2159,curation_candidate,8970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2160,curation_candidate,9449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2161,curation_candidate,1734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2162,curation_candidate,1900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2163,curation_candidate,2541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: oligo used as experimental depletion tool, not safety evidence",2026-06-02T12:33:40+00:00
2164,curation_candidate,2543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2165,curation_candidate,2552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2166,curation_candidate,4451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2167,curation_candidate,8826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2168,curation_candidate,8980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2169,curation_candidate,9460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2170,curation_candidate,9498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2171,curation_candidate,8994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2172,curation_candidate,2573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2173,curation_candidate,2575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2174,curation_candidate,8861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:40+00:00
2175,curation_candidate,9591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2176,curation_candidate,1922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:40+00:00
2177,curation_candidate,2007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2178,curation_candidate,9132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:40+00:00
2179,curation_candidate,9620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2180,curation_candidate,1489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2181,curation_candidate,1815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:40+00:00
2182,curation_candidate,1939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:40+00:00
2183,curation_candidate,2614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2184,curation_candidate,3033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2185,curation_candidate,368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2186,curation_candidate,460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2187,curation_candidate,461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2188,curation_candidate,466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2189,curation_candidate,467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2190,curation_candidate,493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2191,curation_candidate,523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2192,offtarget_evidence,52,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for off-target evidence; location=PubMed abstract.,2026-06-02T12:33:40+00:00
2193,offtarget_evidence,53,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for off-target evidence; location=PubMed abstract.,2026-06-02T12:33:40+00:00
2194,offtarget_evidence,54,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for off-target evidence; location=PubMed abstract.,2026-06-02T12:33:40+00:00
2195,offtarget_evidence,55,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for off-target evidence; location=PubMed abstract.,2026-06-02T12:33:40+00:00
2196,offtarget_evidence,56,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: PubMed abstract source supports primary oligonucleotide offtarget evidence for off-target evidence; location=PubMed abstract.,2026-06-02T12:33:40+00:00
2197,curation_candidate,534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2198,curation_candidate,600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:40+00:00
2199,curation_candidate,670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2200,curation_candidate,991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2201,curation_candidate,993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2202,curation_candidate,1003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2203,curation_candidate,1007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2204,curation_candidate,1008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2205,curation_candidate,1055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2206,curation_candidate,1073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2207,curation_candidate,1115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2208,curation_candidate,1116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2209,curation_candidate,1536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2210,curation_candidate,1832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2211,curation_candidate,2665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2212,curation_candidate,2668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2213,curation_candidate,2678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2214,curation_candidate,2684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2215,curation_candidate,2687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2216,curation_candidate,2694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2217,curation_candidate,2700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2218,curation_candidate,3093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2219,curation_candidate,3121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:40+00:00
2220,curation_candidate,3126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2221,curation_candidate,3197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2222,curation_candidate,3250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2223,curation_candidate,3339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:40+00:00
2224,curation_candidate,3342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2225,curation_candidate,4644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2226,curation_candidate,4668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2227,curation_candidate,4672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2228,curation_candidate,4679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2229,curation_candidate,4694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2230,curation_candidate,4695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2231,curation_candidate,4712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2232,curation_candidate,4722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2233,curation_candidate,4775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2234,curation_candidate,4776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2235,curation_candidate,4845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2236,curation_candidate,4871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2237,curation_candidate,4875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2238,curation_candidate,4887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2239,curation_candidate,4901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2240,curation_candidate,4902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2241,curation_candidate,4954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2242,curation_candidate,4973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2243,curation_candidate,4980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2244,curation_candidate,5057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2245,curation_candidate,5076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2246,curation_candidate,5160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2247,curation_candidate,5180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2248,curation_candidate,5206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2249,curation_candidate,5208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2250,curation_candidate,5228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2251,curation_candidate,5236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2252,curation_candidate,5253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2253,curation_candidate,5280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2254,curation_candidate,5346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2255,curation_candidate,5369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2256,curation_candidate,5427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2257,curation_candidate,5449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2258,curation_candidate,5466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2259,curation_candidate,5532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2260,curation_candidate,5539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2261,curation_candidate,5583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2262,curation_candidate,5617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2263,curation_candidate,5674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2264,curation_candidate,5687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2265,curation_candidate,5739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2266,curation_candidate,5776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2267,curation_candidate,5793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2268,curation_candidate,5859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2269,curation_candidate,5860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2270,curation_candidate,5880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2271,curation_candidate,5945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2272,curation_candidate,5948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2273,curation_candidate,5965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2274,curation_candidate,5976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:40+00:00
2275,curation_candidate,6021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2276,curation_candidate,9635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2277,curation_candidate,9650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2278,curation_candidate,9661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2279,curation_candidate,9685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-02T12:33:40+00:00
2280,curation_candidate,149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:40+00:00
2281,curation_candidate,257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2282,curation_candidate,260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:40+00:00
2283,curation_candidate,821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2284,curation_candidate,1024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2285,curation_candidate,1177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2286,curation_candidate,2182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2287,curation_candidate,2711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2288,curation_candidate,2720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
2289,curation_candidate,2721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2290,curation_candidate,2747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2291,curation_candidate,2784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2292,curation_candidate,2799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2293,curation_candidate,2801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2294,curation_candidate,2811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2295,curation_candidate,3487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2296,curation_candidate,3531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2297,curation_candidate,3570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
2298,curation_candidate,3577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2299,curation_candidate,3661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2300,curation_candidate,6108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2301,curation_candidate,6133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2302,curation_candidate,6378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2303,curation_candidate,6483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-02T12:33:40+00:00
2304,curation_candidate,6638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2305,curation_candidate,6641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2306,curation_candidate,6658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2307,curation_candidate,6662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2308,curation_candidate,6805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2309,curation_candidate,6807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:40+00:00
2310,curation_candidate,6828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2311,curation_candidate,6894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2312,curation_candidate,6941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:40+00:00
2313,curation_candidate,7173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2314,curation_candidate,7191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2315,curation_candidate,7242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2316,curation_candidate,7329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:40+00:00
2317,curation_candidate,7346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2318,curation_candidate,7477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2319,curation_candidate,7554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2320,curation_candidate,7587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2321,curation_candidate,7597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2322,curation_candidate,7623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2323,curation_candidate,7717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2324,curation_candidate,7754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2325,curation_candidate,7779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2326,curation_candidate,7813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2327,curation_candidate,8832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2328,curation_candidate,8904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2329,curation_candidate,9042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2330,curation_candidate,9051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2331,curation_candidate,9063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2332,curation_candidate,9071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2333,curation_candidate,9072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2334,curation_candidate,9073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2335,curation_candidate,9171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2336,curation_candidate,9195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2337,curation_candidate,9207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2338,curation_candidate,9227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2339,curation_candidate,9230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:40+00:00
2340,curation_candidate,9729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2341,curation_candidate,9762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2342,curation_candidate,9778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2343,curation_candidate,9784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2344,curation_candidate,9891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2345,curation_candidate,9941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2346,curation_candidate,9988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2347,curation_candidate,10044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2348,curation_candidate,175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2349,curation_candidate,188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:40+00:00
2350,curation_candidate,1288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2351,curation_candidate,2303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2352,curation_candidate,2820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2353,curation_candidate,2841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2354,curation_candidate,2852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2355,curation_candidate,2855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2356,curation_candidate,2877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2357,curation_candidate,3985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2358,curation_candidate,4008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2359,curation_candidate,4091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2360,curation_candidate,4165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2361,curation_candidate,4173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2362,curation_candidate,7953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2363,curation_candidate,7975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2364,curation_candidate,8034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2365,curation_candidate,8090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2366,curation_candidate,8123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2367,curation_candidate,8126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:40+00:00
2368,curation_candidate,8160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2369,curation_candidate,8172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: physicochemical/fluorescence assay, not primary safety/off-target evidence",2026-06-02T12:33:40+00:00
2370,curation_candidate,8185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2371,curation_candidate,8208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2372,curation_candidate,8236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2373,curation_candidate,8299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2374,curation_candidate,8345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2375,curation_candidate,8499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2376,curation_candidate,9078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2377,curation_candidate,9084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2378,curation_candidate,9290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2379,curation_candidate,9328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2380,curation_candidate,9333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2381,curation_candidate,9353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2382,curation_candidate,10208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2383,curation_candidate,10213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2384,curation_candidate,633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2385,curation_candidate,2406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2386,curation_candidate,2884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-02T12:33:40+00:00
2387,curation_candidate,2893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2388,curation_candidate,2905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2389,curation_candidate,2906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2390,curation_candidate,2913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2391,curation_candidate,2922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2392,curation_candidate,2923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2393,curation_candidate,2925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2394,curation_candidate,4200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2395,curation_candidate,4266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2396,curation_candidate,4280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2397,curation_candidate,8733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2398,curation_candidate,8736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2399,curation_candidate,8746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2400,curation_candidate,9091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2401,curation_candidate,1988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2402,curation_candidate,2461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2403,curation_candidate,2492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:40+00:00
2404,curation_candidate,2935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2405,curation_candidate,2936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2406,curation_candidate,2937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2407,curation_candidate,2939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2408,curation_candidate,2943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2409,curation_candidate,2959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2410,curation_candidate,4335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2411,curation_candidate,4337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2412,curation_candidate,1043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
2413,curation_candidate,2516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2414,curation_candidate,2521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2415,curation_candidate,2528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2416,curation_candidate,2971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2417,curation_candidate,2972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2418,curation_candidate,2975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2419,curation_candidate,2978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2420,curation_candidate,4428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2421,curation_candidate,9098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2422,curation_candidate,9102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2423,curation_candidate,9105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:40+00:00
2424,curation_candidate,1440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2425,curation_candidate,1444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2426,curation_candidate,1799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:40+00:00
2427,curation_candidate,2537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2428,curation_candidate,2989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:40+00:00
2429,curation_candidate,2990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:40+00:00
2430,curation_candidate,2992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:40+00:00
2431,curation_candidate,3001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2432,curation_candidate,3008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2433,curation_candidate,3023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:40+00:00
2434,curation_candidate,4467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:40+00:00
2435,curation_candidate,9114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2436,curation_candidate,9126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2437,curation_candidate,9127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2438,curation_candidate,9485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:40+00:00
2439,curation_candidate,9486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:40+00:00
2440,curation_candidate,9503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2441,curation_candidate,2574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:40+00:00
2442,curation_candidate,9009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2443,curation_candidate,2586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2444,curation_candidate,4524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:40+00:00
2445,curation_candidate,1519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:40+00:00
2446,toxicity_endpoint,414,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified ORION-13 clinical safety results for inclisiran; no ALT/AST, bilirubin, creatinine, CK, growth, puberty, or hormonal safety abnormalities were reported at the checked Results safety location.",2026-06-02T12:33:41+00:00
2447,toxicity_endpoint,415,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified mouse IL-4Ralpha ASO treatment result; body weight was comparable during dosing, but safety is secondary to disease-efficacy readouts, so this is non-benchmark grade C.",2026-06-02T12:33:41+00:00
2448,toxicity_endpoint,416,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified original FAERS pharmacovigilance analysis of nusinersen adverse-event reports and risk signal detection at the checked Results location.,2026-06-02T12:33:41+00:00
2449,toxicity_endpoint,417,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified pooled ORION-9/10/11 safety results for inclisiran; treatment-emergent adverse events were largely similar between arms at the checked Results safety location.,2026-06-02T12:33:41+00:00
2450,toxicity_endpoint,418,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified single-ascending-dose clinical safety/PK evidence for AVI-6002 and AVI-6003 phosphorodiamidate morpholino oligomer combinations at the checked abstract/full-text location.,2026-06-02T12:33:41+00:00
2451,curation_candidate,987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2452,curation_candidate,2021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2453,curation_candidate,4739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2454,curation_candidate,4749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2455,curation_candidate,4753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2456,curation_candidate,4855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:41+00:00
2457,curation_candidate,5545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2458,curation_candidate,5666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:41+00:00
2459,curation_candidate,9649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2460,curation_candidate,82,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2461,curation_candidate,486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2462,curation_candidate,2712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2463,curation_candidate,2759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2464,curation_candidate,2803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2465,curation_candidate,6207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2466,curation_candidate,6572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:41+00:00
2467,curation_candidate,7378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:41+00:00
2468,curation_candidate,9031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2469,curation_candidate,9050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-02T12:33:41+00:00
2470,curation_candidate,1028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2471,curation_candidate,1030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2472,curation_candidate,2294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2473,curation_candidate,2812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2474,curation_candidate,2818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2475,curation_candidate,2846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2476,curation_candidate,2859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2477,curation_candidate,2864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2478,curation_candidate,2866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2479,curation_candidate,7971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2480,curation_candidate,8144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:41+00:00
2481,curation_candidate,8840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2482,curation_candidate,9370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2483,curation_candidate,2395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:41+00:00
2484,curation_candidate,2915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2485,curation_candidate,2920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2486,curation_candidate,2941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2487,curation_candidate,2950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2488,curation_candidate,2953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2489,curation_candidate,2967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-02T12:33:41+00:00
2490,curation_candidate,2977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2491,curation_candidate,9100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2492,curation_candidate,9107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2493,curation_candidate,3026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2494,curation_candidate,8973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:41+00:00
2495,curation_candidate,9131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2496,curation_candidate,2016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2497,curation_candidate,5066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2498,curation_candidate,5309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2499,curation_candidate,5589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2500,curation_candidate,686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2501,curation_candidate,1168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2502,curation_candidate,1622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2503,curation_candidate,1649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2504,curation_candidate,2131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: aptamer-functionalized hydrogel/protein delivery safety, not primary therapeutic oligonucleotide safety evidence",2026-06-02T12:33:41+00:00
2505,curation_candidate,2159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2506,curation_candidate,2177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-02T12:33:41+00:00
2507,curation_candidate,2215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2508,curation_candidate,3911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2509,curation_candidate,6091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2510,curation_candidate,6413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: aptamer-nanoparticle chemotherapy delivery hemolysis, not ASO/siRNA/therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2511,curation_candidate,6690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2512,curation_candidate,7455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2513,curation_candidate,7537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2514,curation_candidate,7572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2515,curation_candidate,697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2516,curation_candidate,1549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2517,curation_candidate,2348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:41+00:00
2518,curation_candidate,7993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2519,curation_candidate,8187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2520,curation_candidate,2410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2521,curation_candidate,10271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2522,curation_candidate,2512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2523,curation_candidate,1727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2524,curation_candidate,9507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2525,curation_candidate,8777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2526,curation_candidate,66,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:41+00:00
2527,curation_candidate,773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2528,curation_candidate,783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: review/guidance/protocol rather than primary safety/off-target evidence,2026-06-02T12:33:41+00:00
2529,curation_candidate,1090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2530,curation_candidate,2036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2531,curation_candidate,2081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2532,curation_candidate,2633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2533,curation_candidate,2661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2534,curation_candidate,4688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2535,curation_candidate,4738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2536,curation_candidate,4859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2537,curation_candidate,4910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2538,curation_candidate,5130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2539,curation_candidate,5289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2540,curation_candidate,5316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2541,curation_candidate,5342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2542,curation_candidate,5478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2543,curation_candidate,5736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2544,curation_candidate,5778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2545,curation_candidate,5809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2546,curation_candidate,9024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2547,curation_candidate,9655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2548,curation_candidate,227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: commentary/correction, not primary evidence",2026-06-02T12:33:41+00:00
2549,curation_candidate,688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: commentary/correction, not primary evidence",2026-06-02T12:33:41+00:00
2550,curation_candidate,835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2551,curation_candidate,1020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2552,curation_candidate,1023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2553,curation_candidate,1667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:41+00:00
2554,curation_candidate,2117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2555,curation_candidate,2183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-02T12:33:41+00:00
2556,curation_candidate,2243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2557,curation_candidate,2736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2558,curation_candidate,2781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2559,curation_candidate,2809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2560,curation_candidate,6067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-02T12:33:41+00:00
2561,curation_candidate,6172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2562,curation_candidate,6213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:41+00:00
2563,curation_candidate,6300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2564,curation_candidate,6362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2565,curation_candidate,6485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2566,curation_candidate,6515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2567,curation_candidate,6602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2568,curation_candidate,6738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2569,curation_candidate,6782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2570,curation_candidate,6784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2571,curation_candidate,6837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2572,curation_candidate,6909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2573,curation_candidate,7050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2574,curation_candidate,7117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2575,curation_candidate,7298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2576,curation_candidate,7367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2577,curation_candidate,7408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2578,curation_candidate,7466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-02T12:33:41+00:00
2579,curation_candidate,7558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2580,curation_candidate,7866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2581,curation_candidate,8805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2582,curation_candidate,9026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2583,curation_candidate,9049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-02T12:33:41+00:00
2584,curation_candidate,9752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2585,curation_candidate,9899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2586,curation_candidate,9900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2587,curation_candidate,9924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2588,curation_candidate,2876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2589,curation_candidate,7890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2590,curation_candidate,8184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2591,curation_candidate,8341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2592,curation_candidate,8445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2593,curation_candidate,8828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2594,curation_candidate,8911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2595,curation_candidate,10102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2596,curation_candidate,10141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2597,curation_candidate,10227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2598,curation_candidate,1359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2599,curation_candidate,2398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2600,curation_candidate,2902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2601,curation_candidate,8577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2602,curation_candidate,8625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2603,curation_candidate,8930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2604,curation_candidate,8957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2605,curation_candidate,10267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2606,curation_candidate,2465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: probiotic genome safety study, not therapeutic oligonucleotide evidence",2026-06-02T12:33:41+00:00
2607,curation_candidate,2968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2608,curation_candidate,2988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2609,curation_candidate,9099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2610,curation_candidate,1733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2611,curation_candidate,9002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2612,toxicity_endpoint,419,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified primary CNS ASO safety study; intrathecal phosphorothioate ASOs caused dose-dependent acute inhibition/paresis that peaked after dosing and reversed within 24 h.,2026-06-02T12:33:41+00:00
2613,toxicity_endpoint,420,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified specific toxicology details for GalNAc-siRNA platform, including NOAEL and ALT/AST/urea observations; source is Discussion, so grade C/non-benchmark.",2026-06-02T12:33:41+00:00
2614,toxicity_endpoint,421,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results biosafety assays for TET3 siRNA LNPs; hemolysis stayed below 5% and CCK-8 showed no significant cytotoxicity over tested concentrations.,2026-06-02T12:33:41+00:00
2615,toxicity_endpoint,422,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified in vitro siRNA-LNP transfection Results; effective ionizable lipid formulations generally maintained cell viability at or above 80%.,2026-06-02T12:33:41+00:00
2616,toxicity_endpoint,423,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results biocompatibility evidence for CaP-siSlc31a1; formulation showed lower cytotoxicity than liposomal comparator and maintained over 80% cell viability.,2026-06-02T12:33:41+00:00
2617,toxicity_endpoint,424,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified in vivo biosafety Results for FW-LP@siIRF5 using hematology, blood biochemistry, and histology after repeated intravenous dosing.",2026-06-02T12:33:41+00:00
2618,toxicity_endpoint,425,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified porcine intradermal siRNA safety Results; systemic organ exposure was low and cytokines, platelets, WBC, ALT, and kidney marker showed no significant changes.",2026-06-02T12:33:41+00:00
2619,toxicity_endpoint,426,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results cytotoxicity assay for siRNA nanocarriers before and after nebulisation in A549 cells.,2026-06-02T12:33:41+00:00
2620,toxicity_endpoint,427,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results systemic safety assessment for siPD-L1 extracellular-vesicle treatment; major-organ H&E and body weight indicated minimal systemic toxicity.,2026-06-02T12:33:41+00:00
2621,toxicity_endpoint,428,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified preliminary safety Results for inhaled MSC-NVs-siRNA; BALF cytokines/cells and lung histology showed no significant acute safety signal.,2026-06-02T12:33:41+00:00
2622,toxicity_endpoint,429,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results hepatotoxicity/kidney-function assessment after intranasal peptide-mannan RNA polyplex dosing; serum biochemistry and histology showed no significant toxicity.,2026-06-02T12:33:41+00:00
2623,toxicity_endpoint,430,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified article conclusion reporting no toxicity with systemically delivered siRNA polyplexes; source is conclusion-level, so grade C/non-benchmark.",2026-06-02T12:33:41+00:00
2624,toxicity_endpoint,431,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified discussion-level report that treated mice showed no tissue/organ toxicity or adverse effects; grade C/non-benchmark.,2026-06-02T12:33:41+00:00
2625,toxicity_endpoint,432,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results biocompatibility testing for siRNA-loaded gelatin/CaP nanoparticle delivery in calvarial mesenchymal stromal cell microtissues.,2026-06-02T12:33:41+00:00
2626,toxicity_endpoint,433,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results paragraph for siRNA-antibody delivery; prazosin enhancer was reported biologically inert with no cytotoxicity or transcriptional misregulation.,2026-06-02T12:33:41+00:00
2627,toxicity_endpoint,434,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified in vivo biosafety Results for intranasal siRNA LNP therapy; CBC, ALT/AST, bilirubin, creatinine, BUN, major-organ H&E, and nasal mucosa histology showed no overt toxicity.",2026-06-02T12:33:41+00:00
2628,toxicity_endpoint,435,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results blood-compatibility/hemolysis experiment for curcumin coacervate siRNA delivery formulation.,2026-06-02T12:33:41+00:00
2629,toxicity_endpoint,436,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified in vivo safety assessment of siRNA@VG-Exos using major-organ H&E and renal/hepatic serum biochemical markers.,2026-06-02T12:33:41+00:00
2630,toxicity_endpoint,437,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified Results side-effect assessment for LNP-delivered SNORA49 RNA/SOX9 ASO treatment; treated mice had normal liver/kidney/spleen morphology, comparable body weight/organ size, and no significant cytokine increase.",2026-06-02T12:33:41+00:00
2631,toxicity_endpoint,438,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results cytotoxicity assays for siRNA-loaded nanozyme formulations in BMDMs and PC12 cells over 24-72 h.,2026-06-02T12:33:41+00:00
2632,toxicity_endpoint,439,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified in vivo biocompatibility Results for pMSNC@ISG15 siRNA; body weight, hematology, ALT/AST, BUN/Cr, and major-organ histology showed no abnormalities.",2026-06-02T12:33:41+00:00
2633,toxicity_endpoint,440,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results systemic delivery safety for scrambled miRNA/siRNA-loaded SANGs; high-dose and repeat-dose studies reported no significant toxicity.,2026-06-02T12:33:41+00:00
2634,toxicity_endpoint,441,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results cytotoxicity measurements for cationic and anionic siRNA lipoplex formulations in MCF-7-Luc and HeLa-Luc cells.,2026-06-02T12:33:41+00:00
2635,toxicity_endpoint,442,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified ASO-associated thrombocytopenia evidence in NHPs; ISIS 405879 treatment was linked to severe platelet-count reduction and immune-cell changes.,2026-06-02T12:33:41+00:00
2636,toxicity_endpoint,443,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified Results cell-viability evidence for LNP TNF-alpha siRNA; high-concentration LNP exposure did not significantly affect RAW 264.7 viability.,2026-06-02T12:33:41+00:00
2637,toxicity_endpoint,444,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified primary siRNA silk-sphere delivery paragraph; MTT evidence indicated the particles did not directly reduce cellular metabolism/cell viability.,2026-06-02T12:33:41+00:00
2638,toxicity_endpoint,445,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,"accepted: verified primary biodistribution evidence; tetrameric siRNA constructs reduced kidney accumulation relative to single siRNA, a safety-relevant renal exposure endpoint; grade C/non-benchmark.",2026-06-02T12:33:41+00:00
2639,toxicity_endpoint,446,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,machine_v1_keyword_classifier,accepted: verified primary cell-compatibility Results for siRNA carbon-nanodot complexes; lower ratios were cytocompatible and erythrocompatibility was also assessed.,2026-06-02T12:33:41+00:00
2640,curation_candidate,4917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2641,curation_candidate,5041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2642,curation_candidate,5127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2643,curation_candidate,5148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2644,curation_candidate,5324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2645,curation_candidate,5484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2646,curation_candidate,6116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2647,curation_candidate,6361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2648,curation_candidate,6861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2649,curation_candidate,7008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2650,curation_candidate,7265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2651,curation_candidate,7431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: computational/design-only off-target prediction without observed evidence,2026-06-02T12:33:41+00:00
2652,curation_candidate,7511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2653,curation_candidate,7649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: source supports toxicity/PKM pharmacology context, not verified off-target evidence for the queued offtarget row",2026-06-02T12:33:41+00:00
2654,curation_candidate,7833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2655,curation_candidate,9754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2656,curation_candidate,7891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2657,curation_candidate,7939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2658,curation_candidate,7984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2659,curation_candidate,8041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2660,curation_candidate,8209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2661,curation_candidate,8227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2662,curation_candidate,8380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2663,curation_candidate,2484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: shRNA/retinal gene therapy context outside core ASO/siRNA therapeutic off-target evidence,2026-06-02T12:33:41+00:00
2664,curation_candidate,1424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: aptamer material/drug-delivery safety, not core ASO/siRNA therapeutic oligo evidence",2026-06-02T12:33:41+00:00
2665,curation_candidate,4376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2666,curation_candidate,4616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2667,curation_candidate,4999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2668,curation_candidate,5873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-02T12:33:41+00:00
2669,curation_candidate,5973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: physicochemical/fluorescence assay, not primary safety/off-target evidence",2026-06-02T12:33:41+00:00
2670,curation_candidate,6194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2671,curation_candidate,6510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2672,curation_candidate,7108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: aptamer material/drug-delivery safety, not core ASO/siRNA therapeutic oligo evidence",2026-06-02T12:33:41+00:00
2673,curation_candidate,7877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: delivery/efficacy specificity rather than oligo off-target evidence,2026-06-02T12:33:41+00:00
2674,curation_candidate,8331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2675,curation_candidate,8491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2676,curation_candidate,10196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2677,curation_candidate,4332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:41+00:00
2678,curation_candidate,2550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2679,curation_candidate,1924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no off-target/seed/mismatch/transcriptome evidence in verified source text,2026-06-02T12:33:41+00:00
2680,curation_candidate,2615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2681,curation_candidate,341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease efficacy/body-weight clinical score context, not primary product safety evidence",2026-06-02T12:33:41+00:00
2682,curation_candidate,350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: efficacy and differentiation readout, not primary oligo safety evidence",2026-06-02T12:33:41+00:00
2683,curation_candidate,389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2684,curation_candidate,504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2685,curation_candidate,529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2686,curation_candidate,542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2687,curation_candidate,550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2688,curation_candidate,555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: discussion/prior-platform safety statement, not primary safety evidence in verified source location",2026-06-02T12:33:41+00:00
2689,curation_candidate,570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2690,curation_candidate,596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2691,curation_candidate,601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2692,curation_candidate,802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: therapeutic neuroinflammation pathway response, not product safety/toxicity endpoint",2026-06-02T12:33:41+00:00
2693,curation_candidate,1058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2694,curation_candidate,1062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: siRNA knockdown used for astrocyte cytokine biology, not oligo product safety evidence",2026-06-02T12:33:41+00:00
2695,curation_candidate,1071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2696,curation_candidate,1089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:41+00:00
2697,curation_candidate,2067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: discussion cites prior PMO toxicity, not primary safety evidence in this article",2026-06-02T12:33:41+00:00
2698,curation_candidate,2074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:41+00:00
2699,curation_candidate,2080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:41+00:00
2700,curation_candidate,2656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2701,curation_candidate,2689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2702,curation_candidate,3044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: patent/forecasting analysis, not primary experimental safety evidence",2026-06-02T12:33:41+00:00
2703,curation_candidate,3062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: imaging/theranostic delivery study, not primary safety/off-target evidence",2026-06-02T12:33:41+00:00
2704,curation_candidate,3066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2705,curation_candidate,3069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2706,curation_candidate,3096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: aptamer-guided delivery and prior lactosome safety profile, not primary oligo safety evidence",2026-06-02T12:33:41+00:00
2707,curation_candidate,3098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2708,curation_candidate,3105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2709,curation_candidate,3107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2710,curation_candidate,3109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2711,curation_candidate,3130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2712,curation_candidate,3131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2713,curation_candidate,3133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2714,curation_candidate,3144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2715,curation_candidate,3146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2716,curation_candidate,3160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2717,curation_candidate,3163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2718,curation_candidate,3170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: antitumor immune-efficacy readout, not primary safety/toxicity evidence",2026-06-02T12:33:41+00:00
2719,curation_candidate,3175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2720,curation_candidate,3182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2721,curation_candidate,3185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2722,curation_candidate,3201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: in vivo silencing efficacy/biodistribution context without safety endpoint,2026-06-02T12:33:41+00:00
2723,curation_candidate,3216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: figure caption for silencing efficiency, not safety/toxicity evidence",2026-06-02T12:33:41+00:00
2724,curation_candidate,3226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2725,curation_candidate,3235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review article, not primary safety evidence",2026-06-02T12:33:41+00:00
2726,curation_candidate,3246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2727,curation_candidate,3251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism cell viability after siRNA knockdown, not oligo safety evidence",2026-06-02T12:33:41+00:00
2728,curation_candidate,3262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2729,curation_candidate,3266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: future safety optimization discussion, not primary safety result",2026-06-02T12:33:41+00:00
2730,curation_candidate,3291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2731,curation_candidate,3309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: Dox/siRNA co-delivery safety is confounded by chemotherapy payload; not core oligo safety release evidence,2026-06-02T12:33:41+00:00
2732,curation_candidate,3322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2733,curation_candidate,3327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2734,curation_candidate,3352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: protein/OVA formulation viability context, not direct siRNA safety evidence",2026-06-02T12:33:41+00:00
2735,curation_candidate,4626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2736,curation_candidate,4657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2737,curation_candidate,4684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2738,curation_candidate,4685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2739,curation_candidate,4708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cancer cell-killing efficacy after siRNA knockdown, not safety evidence",2026-06-02T12:33:41+00:00
2740,curation_candidate,4756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2741,curation_candidate,4761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2742,curation_candidate,4763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2743,curation_candidate,4764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2744,curation_candidate,4786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2745,curation_candidate,4798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:41+00:00
2746,curation_candidate,4814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2747,curation_candidate,4818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2748,curation_candidate,4835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2749,curation_candidate,4841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2750,curation_candidate,4861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2751,curation_candidate,4866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:41+00:00
2752,curation_candidate,4903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2753,curation_candidate,4908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2754,curation_candidate,4912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2755,curation_candidate,4932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: probiotic/genome safety study, not therapeutic oligonucleotide evidence",2026-06-02T12:33:41+00:00
2756,curation_candidate,4938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2757,curation_candidate,4941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2758,curation_candidate,4950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-02T12:33:41+00:00
2759,curation_candidate,5008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: abstract lacks direct oligo product safety result,2026-06-02T12:33:41+00:00
2760,curation_candidate,5010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: out-of-scope modality or source context,2026-06-02T12:33:41+00:00
2761,curation_candidate,5012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2762,curation_candidate,5027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2763,curation_candidate,5039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2764,curation_candidate,5101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2765,curation_candidate,5103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2766,curation_candidate,5150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2767,curation_candidate,5155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2768,curation_candidate,5194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: targeting/fabrication context without primary toxicity endpoint,2026-06-02T12:33:41+00:00
2769,curation_candidate,5200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2770,curation_candidate,5214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: piceatannol/small-molecule treatment context, not therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2771,curation_candidate,5218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2772,curation_candidate,5220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2773,curation_candidate,5222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2774,curation_candidate,5249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2775,curation_candidate,5261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2776,curation_candidate,5284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2777,curation_candidate,5285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2778,curation_candidate,5310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2779,curation_candidate,5323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2780,curation_candidate,5325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2781,curation_candidate,5328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2782,curation_candidate,5330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2783,curation_candidate,5348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2784,curation_candidate,5352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2785,curation_candidate,5377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2786,curation_candidate,5382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2787,curation_candidate,5392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2788,curation_candidate,5402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2789,curation_candidate,5412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:41+00:00
2790,curation_candidate,5414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2791,curation_candidate,5421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2792,curation_candidate,5432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2793,curation_candidate,5437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2794,curation_candidate,5492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2795,curation_candidate,5507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2796,curation_candidate,5511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2797,curation_candidate,5512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2798,curation_candidate,5516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2799,curation_candidate,5517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2800,curation_candidate,5522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2801,curation_candidate,5525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2802,curation_candidate,5544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2803,curation_candidate,5600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2804,curation_candidate,5611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2805,curation_candidate,5627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2806,curation_candidate,5629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:41+00:00
2807,curation_candidate,5632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2808,curation_candidate,5668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2809,curation_candidate,5685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: methods-only siRNA transfection description, no primary safety endpoint",2026-06-02T12:33:41+00:00
2810,curation_candidate,5690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:41+00:00
2811,curation_candidate,5720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2812,curation_candidate,5730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2813,curation_candidate,5732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2814,curation_candidate,5733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2815,curation_candidate,5741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:41+00:00
2816,curation_candidate,5771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2817,curation_candidate,5773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2818,curation_candidate,5805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:41+00:00
2819,curation_candidate,5810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2820,curation_candidate,5820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2821,curation_candidate,5824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2822,curation_candidate,5851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2823,curation_candidate,5852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2824,curation_candidate,5853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:41+00:00
2825,curation_candidate,5877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety/toxicity endpoint is not linked to the oligo molecule or delivery product,2026-06-02T12:33:41+00:00
2826,curation_candidate,5878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2827,curation_candidate,5922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2828,curation_candidate,5952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:41+00:00
2829,curation_candidate,5999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2830,curation_candidate,6037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review or systematic review, not primary evidence",2026-06-02T12:33:41+00:00
2831,curation_candidate,9633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2832,curation_candidate,9634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2833,curation_candidate,9637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2834,curation_candidate,9647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity belongs to disease/toxin model where oligo is a perturbation tool,2026-06-02T12:33:41+00:00
2835,curation_candidate,9659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2836,curation_candidate,9665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2837,curation_candidate,135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: ASO activity/nonspecific binding mechanism without direct safety endpoint,2026-06-02T12:33:41+00:00
2838,curation_candidate,440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review article, not primary safety evidence",2026-06-02T12:33:41+00:00
2839,curation_candidate,842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2840,curation_candidate,1026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2841,curation_candidate,1027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2842,curation_candidate,1126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: aptamer material/drug-delivery safety, not core ASO/siRNA therapeutic oligo evidence",2026-06-02T12:33:41+00:00
2843,curation_candidate,1181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2844,curation_candidate,1190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2845,curation_candidate,1230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2846,curation_candidate,2108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2847,curation_candidate,2115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2848,curation_candidate,2139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2849,curation_candidate,2162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2850,curation_candidate,2173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2851,curation_candidate,2180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2852,curation_candidate,2197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2853,curation_candidate,2218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2854,curation_candidate,2238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2855,curation_candidate,2245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2856,curation_candidate,2745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2857,curation_candidate,2756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2858,curation_candidate,2758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2859,curation_candidate,2766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2860,curation_candidate,2786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2861,curation_candidate,2790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2862,curation_candidate,3363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2863,curation_candidate,3367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2864,curation_candidate,3380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2865,curation_candidate,3387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2866,curation_candidate,3392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2867,curation_candidate,3394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2868,curation_candidate,3395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2869,curation_candidate,3401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2870,curation_candidate,3410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2871,curation_candidate,3443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2872,curation_candidate,3461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2873,curation_candidate,3464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2874,curation_candidate,3470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2875,curation_candidate,3472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2876,curation_candidate,3474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2877,curation_candidate,3480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2878,curation_candidate,3499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2879,curation_candidate,3509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2880,curation_candidate,3526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2881,curation_candidate,3551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2882,curation_candidate,3553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2883,curation_candidate,3584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2884,curation_candidate,3590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2885,curation_candidate,3592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2886,curation_candidate,3619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2887,curation_candidate,3635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2888,curation_candidate,3638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2889,curation_candidate,3651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2890,curation_candidate,3654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: PubMed abstract describes photothermal antitumor efficacy, not safety endpoint",2026-06-02T12:33:41+00:00
2891,curation_candidate,3656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2892,curation_candidate,3672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2893,curation_candidate,3675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2894,curation_candidate,3678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2895,curation_candidate,3687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2896,curation_candidate,3689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2897,curation_candidate,3713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2898,curation_candidate,3717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2899,curation_candidate,3745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2900,curation_candidate,3747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract describes siRNA delivery efficacy without direct safety result,2026-06-02T12:33:41+00:00
2901,curation_candidate,3760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2902,curation_candidate,3781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2903,curation_candidate,3784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2904,curation_candidate,3790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:41+00:00
2905,curation_candidate,3792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract lacks direct oligo product safety result,2026-06-02T12:33:41+00:00
2906,curation_candidate,3801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2907,curation_candidate,3808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2908,curation_candidate,3819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2909,curation_candidate,3831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2910,curation_candidate,3841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2911,curation_candidate,3865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2912,curation_candidate,3871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2913,curation_candidate,3903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2914,curation_candidate,3909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2915,curation_candidate,3917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2916,curation_candidate,3927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2917,curation_candidate,3941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: introduction/background anchor without primary safety/off-target result,2026-06-02T12:33:41+00:00
2918,curation_candidate,3946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2919,curation_candidate,3951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2920,curation_candidate,3953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2921,curation_candidate,3955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2922,curation_candidate,6057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2923,curation_candidate,6065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2924,curation_candidate,6069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2925,curation_candidate,6079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2926,curation_candidate,6081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2927,curation_candidate,6090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source location unsupported; no full-text anchor or PubMed abstract evidence,2026-06-02T12:33:41+00:00
2928,curation_candidate,6093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2929,curation_candidate,6097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2930,curation_candidate,6101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2931,curation_candidate,6104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2932,curation_candidate,6112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2933,curation_candidate,6114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: endogenous antisense/lncRNA biology, not therapeutic oligo evidence",2026-06-02T12:33:41+00:00
2934,curation_candidate,6118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2935,curation_candidate,6122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2936,curation_candidate,6125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2937,curation_candidate,6138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2938,curation_candidate,6142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: toxicity endpoint belongs to non-oligonucleotide drug or exposure,2026-06-02T12:33:41+00:00
2939,curation_candidate,6154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2940,curation_candidate,6164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2941,curation_candidate,6182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2942,curation_candidate,6185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2943,curation_candidate,6206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2944,curation_candidate,6235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2945,curation_candidate,6240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2946,curation_candidate,6247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2947,curation_candidate,6253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2948,curation_candidate,6258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2949,curation_candidate,6263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2950,curation_candidate,6268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2951,curation_candidate,6276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: viral/gene-editing/shRNA modality outside core therapeutic oligo evidence,2026-06-02T12:33:41+00:00
2952,curation_candidate,6279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2953,curation_candidate,6281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2954,curation_candidate,6283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2955,curation_candidate,6286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: aptamer material/drug-delivery safety, not core ASO/siRNA therapeutic oligo evidence",2026-06-02T12:33:41+00:00
2956,curation_candidate,6297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2957,curation_candidate,6303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2958,curation_candidate,6307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2959,curation_candidate,6312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2960,curation_candidate,6320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2961,curation_candidate,6322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2962,curation_candidate,6323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2963,curation_candidate,6335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2964,curation_candidate,6339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2965,curation_candidate,6348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2966,curation_candidate,6349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2967,curation_candidate,6356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2968,curation_candidate,6360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2969,curation_candidate,6365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2970,curation_candidate,6376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2971,curation_candidate,6387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2972,curation_candidate,6390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2973,curation_candidate,6398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2974,curation_candidate,6400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2975,curation_candidate,6408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: diagnostic or assay-development article, not therapeutic oligo safety evidence",2026-06-02T12:33:41+00:00
2976,curation_candidate,6411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2977,curation_candidate,6430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2978,curation_candidate,6446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
2979,curation_candidate,6448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2980,curation_candidate,6452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2981,curation_candidate,6476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2982,curation_candidate,6487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2983,curation_candidate,6496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2984,curation_candidate,6497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
2985,curation_candidate,6500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2986,curation_candidate,6508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2987,curation_candidate,6522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2988,curation_candidate,6523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: safety endpoint belongs to non-oligonucleotide therapeutic,2026-06-02T12:33:41+00:00
2989,curation_candidate,6531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2990,curation_candidate,6536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2991,curation_candidate,6551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
2992,curation_candidate,6552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
2993,curation_candidate,6553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2994,curation_candidate,6560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
2995,curation_candidate,6585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2996,curation_candidate,6598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
2997,curation_candidate,6620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
2998,curation_candidate,6671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
2999,curation_candidate,6676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
3000,curation_candidate,6692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
3001,curation_candidate,6708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
3002,curation_candidate,6717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
3003,curation_candidate,6727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
3004,curation_candidate,6731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: cytotoxicity appears to be efficacy/cancer-killing readout, not safety evidence",2026-06-02T12:33:41+00:00
3005,curation_candidate,6743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: mRNA delivery context, not ASO/siRNA/off-target evidence",2026-06-02T12:33:41+00:00
3006,curation_candidate,6758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
3007,curation_candidate,6776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
3008,curation_candidate,6799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
3009,curation_candidate,6802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no primary safety/toxicity endpoint in verified source text,2026-06-02T12:33:41+00:00
3010,curation_candidate,6811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
3011,curation_candidate,6815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
3012,curation_candidate,6897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
3013,curation_candidate,6906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
3014,curation_candidate,6910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: no ASO/siRNA/oligonucleotide molecule support in source text,2026-06-02T12:33:41+00:00
3015,curation_candidate,6918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
3016,curation_candidate,6945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
3017,curation_candidate,6957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: PubMed abstract does not report a direct oligo/product safety result,2026-06-02T12:33:41+00:00
3018,curation_candidate,6963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: Dox/siRNA co-delivery efficacy abstract without primary safety endpoint,2026-06-02T12:33:41+00:00
3019,curation_candidate,6976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
3020,curation_candidate,6999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: agricultural/plant/insect/non-therapeutic RNAi context,2026-06-02T12:33:41+00:00
3021,curation_candidate,7000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: disease-mechanism study using RNA perturbation, not oligo safety evidence",2026-06-02T12:33:41+00:00
3022,curation_candidate,7003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,"reject reason: review/meta-analysis, not primary evidence",2026-06-02T12:33:41+00:00
3023,curation_candidate,7004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,machine_v1_keyword_classifier,reject reason: source text is background/narrative rather than primary result,2026-06-02T12:33:41+00:00
3024,toxicity_endpoint,447,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: NLP-exosome STAT3-siRNA complex showed in vitro biocompatibility by LDH release assay with no cell damage during transfection; graded C because safety evidence is brief.,2026-06-02T14:37:29+00:00
3025,toxicity_endpoint,448,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: P-HyOMe-WRAP5:siF3 exposure in human cardiomyocytes was reported below the cytotoxicity threshold with no specific cytotoxicity observed.,2026-06-02T14:37:29+00:00
3026,toxicity_endpoint,449,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Results: blood biochemistry and histology were unchanged versus PBS and C5b9, C3a, and MCP-1 immunogenicity markers remained stable after BE-ST@siRNA treatment.",2026-06-02T14:37:29+00:00
3027,toxicity_endpoint,450,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: HUVEC viability remained above 90% after exposure to PEI/PHD2 siRNA nanocomplexes and no significant cytotoxicity differences were observed.,2026-06-02T14:37:29+00:00
3028,toxicity_endpoint,451,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Safety Assessment: PLGA-CpG@ID8-M and free CpG did not significantly affect RAW264.7 viability at 0-2 uM, and 0.5 uM nanovaccine showed no long-term cytotoxicity in BMDMs.",2026-06-02T14:37:29+00:00
3029,toxicity_endpoint,452,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: siRNA SORT LNPs were reported as well tolerated in vivo with serum chemistry and organ histology safety readouts supporting tolerability.,2026-06-02T14:37:29+00:00
3030,toxicity_endpoint,453,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text toxicity analysis: blinded liver pathology found no maternal or pup liver pathology, while maternal serum testing detected AST elevation/trend after in utero ASO exposure with other liver markers similar.",2026-06-02T14:37:29+00:00
3031,toxicity_endpoint,454,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: MTT testing of siRNA nanoplex formulations in MV3 and ARPE-19 cells found no statistically significant cytotoxicity and viability above 60%.,2026-06-02T14:37:29+00:00
3032,toxicity_endpoint,455,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: GL261-Luc cells exposed to NT-NPs/ASO or Phe-NPs/ASO showed no significant effects on viability or cytotoxicity at tested concentrations.,2026-06-02T14:37:29+00:00
3033,toxicity_endpoint,456,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Safety profiles section: intratracheal nanoscaffold dosing in healthy mice was assessed by BALF IL-6/TNF-alpha, inflammatory cells, and H&E staining; DOTAP/siNC@EM showed minimal inflammatory response.",2026-06-02T14:37:29+00:00
3034,toxicity_endpoint,457,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Safety assessment: TPNs-siRNA hemolysis remained below 5%, body weight and organ indices were unchanged, and serum chemistry/H&E supported systemic tolerability.",2026-06-02T14:37:29+00:00
3035,toxicity_endpoint,458,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Results and Methods: CAP-siRNA knockdown experiments were conducted at nontoxic peptide concentrations and cytotoxicity was measured by LDH release; support is method-linked, so graded C.",2026-06-02T14:37:29+00:00
3036,toxicity_endpoint,459,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Safety evaluation: AA-T3A-C12/siRNA LNP treatment did not further increase ALT, AST, or TBIL in fibrotic mice, did not raise cytokines, and showed no major-organ histological damage.",2026-06-02T14:37:29+00:00
3037,toxicity_endpoint,460,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: r/si-ORF7 showed negligible cytotoxicity up to 100 nM and flexible nano-liposome cytotoxicity to ARPE-19 cells was not observed by CCK-8 assay.,2026-06-02T14:37:29+00:00
3038,toxicity_endpoint,461,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Cytotoxicity Results: MLN/MPLN treatment did not significantly change viability in TZM-bl, MT2, or PBMC cultures compared with control.",2026-06-02T14:37:29+00:00
3039,toxicity_endpoint,462,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Results: ZNF416 siRNA-loaded liposomes entered fibroblasts without cytotoxicity and showed no significant ALT/AST/Scr/BUN/CK-MB, body-weight, or major-organ H&E changes versus controls.",2026-06-02T14:37:29+00:00
3040,toxicity_endpoint,463,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Cytotoxicity Results: CS-OA coated nanoparticles did not affect viability of human CD14+ peripheral-blood monocytes, including at the highest tested concentration.",2026-06-02T14:37:29+00:00
3041,toxicity_endpoint,464,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Results: four repeated intravenous XbNP siRNA doses produced no significant serum AST/ALT difference versus untreated controls, supporting lack of measurable hepatotoxicity.",2026-06-02T14:37:29+00:00
3042,toxicity_endpoint,465,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Results: siSTAT3/DoCh LNP-treated tumor-bearing mice had no visible lung/liver lesions and normal serum ALT/AST, unlike the toxic positive-control group.",2026-06-02T14:37:29+00:00
3043,toxicity_endpoint,466,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: green nanoparticles with or without ASO did not cause obvious cytotoxicity at the transfection concentrations used for single-strand oligonucleotide delivery.,2026-06-02T14:37:29+00:00
3044,toxicity_endpoint,467,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Results paragraph: siRNA LNP potency testing noted limited toxicity at the studied dose; evidence is brief and mixed with mRNA LNP testing, so graded C.",2026-06-02T14:37:29+00:00
3045,toxicity_endpoint,468,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Results: FACS toxicity readout showed 2.15% ethidium-positive cells after mNP treatment versus 3.89% after Lipofectamine, supporting low cytotoxicity of siRNA-loaded mNPs.",2026-06-02T14:37:29+00:00
3046,toxicity_endpoint,469,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full-text Results: cholesterol-, DHA-, and GalNAc-conjugated fully modified siRNAs were reported as well tolerated with no observable adverse events or blood chemistry changes; underlying chemistry data were not shown.",2026-06-02T14:37:29+00:00
3047,toxicity_endpoint,470,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: P-PMO conjugates were tested in human hepatocytes at 40 uM; most showed no significant viability reduction and the selected Br-ApoE(K->A)-PMO retained >85% viability.,2026-06-02T14:37:29+00:00
3048,toxicity_endpoint,471,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full-text Results: high-throughput polyester-siRNA nanoparticle screening reported selected A13-modified polyesters with the lowest cytotoxicity while preserving siLuc delivery activity.,2026-06-02T14:37:29+00:00
3049,toxicity_endpoint,472,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified PubMed abstract: L2-3@siTNF-alpha was described as having good biocompatibility while treating hepatic inflammation; abstract-only support, so graded C.",2026-06-02T14:37:29+00:00
3050,toxicity_endpoint,473,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified PubMed abstract: phase 2a elebsiran treatment, alone or with BRII-179, was explicitly reported as well tolerated in chronic hepatitis B participants.",2026-06-02T14:37:29+00:00
3051,toxicity_endpoint,474,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified PubMed abstract: ISIS 405879, a 2'-MOE ASO, induced severe thrombocytopenia in susceptible cynomolgus monkeys with platelet-bound C3d/C4d and antibody-marker changes.",2026-06-02T14:37:29+00:00
3052,curation_candidate,7017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3053,curation_candidate,7040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3054,curation_candidate,7049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3055,curation_candidate,7078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3056,curation_candidate,7084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3057,curation_candidate,7089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3058,curation_candidate,7091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3059,curation_candidate,7092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3060,curation_candidate,7094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3061,curation_candidate,7100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3062,curation_candidate,7120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3063,curation_candidate,7145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3064,curation_candidate,7163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3065,curation_candidate,7176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3066,curation_candidate,7179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3067,curation_candidate,7206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3068,curation_candidate,7219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3069,curation_candidate,7220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3070,curation_candidate,7236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3071,curation_candidate,7244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3072,curation_candidate,7255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3073,curation_candidate,7297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3074,curation_candidate,7300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3075,curation_candidate,7305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3076,curation_candidate,7323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3077,curation_candidate,7325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3078,curation_candidate,7331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3079,curation_candidate,7356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3080,curation_candidate,7357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3081,curation_candidate,7387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3082,curation_candidate,7388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3083,curation_candidate,7390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3084,curation_candidate,7400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3085,curation_candidate,7406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3086,curation_candidate,7443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3087,curation_candidate,7451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3088,curation_candidate,7456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3089,curation_candidate,7460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3090,curation_candidate,7474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3091,curation_candidate,7478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3092,curation_candidate,7516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3093,curation_candidate,7526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3094,curation_candidate,7539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3095,curation_candidate,7557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3096,curation_candidate,7563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3097,curation_candidate,7589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3098,curation_candidate,7608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3099,curation_candidate,7615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3100,curation_candidate,7625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3101,curation_candidate,7628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3102,curation_candidate,7632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3103,curation_candidate,7636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3104,curation_candidate,7640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3105,curation_candidate,7674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3106,curation_candidate,7700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3107,curation_candidate,7723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3108,curation_candidate,7742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3109,curation_candidate,7755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3110,curation_candidate,7756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3111,curation_candidate,7774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3112,curation_candidate,7780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3113,curation_candidate,7820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3114,curation_candidate,7834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3115,curation_candidate,8892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3116,curation_candidate,8900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3117,curation_candidate,9056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3118,curation_candidate,9065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3119,curation_candidate,9155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3120,curation_candidate,9158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3121,curation_candidate,9164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3122,curation_candidate,9167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3123,curation_candidate,9174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3124,curation_candidate,9188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3125,curation_candidate,9193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3126,curation_candidate,9198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3127,curation_candidate,9200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3128,curation_candidate,9210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3129,curation_candidate,9213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3130,curation_candidate,9216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3131,curation_candidate,9220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3132,curation_candidate,9236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3133,curation_candidate,9241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3134,curation_candidate,9245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3135,curation_candidate,9260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3136,curation_candidate,9262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3137,curation_candidate,9716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3138,curation_candidate,9720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3139,curation_candidate,9723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3140,curation_candidate,9728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3141,curation_candidate,9736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3142,curation_candidate,9738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3143,curation_candidate,9744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3144,curation_candidate,9747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3145,curation_candidate,9748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3146,curation_candidate,9765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3147,curation_candidate,9786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3148,curation_candidate,9787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3149,curation_candidate,9790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3150,curation_candidate,9792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3151,curation_candidate,9797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3152,curation_candidate,9812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3153,curation_candidate,9814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3154,curation_candidate,9824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3155,curation_candidate,9837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3156,curation_candidate,9855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3157,curation_candidate,9865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3158,curation_candidate,9866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3159,curation_candidate,9870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3160,curation_candidate,9872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3161,curation_candidate,9876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3162,curation_candidate,9877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3163,curation_candidate,9878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3164,curation_candidate,9879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3165,curation_candidate,9893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3166,curation_candidate,9896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3167,curation_candidate,9910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3168,curation_candidate,9923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3169,curation_candidate,9937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3170,curation_candidate,9940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3171,curation_candidate,9946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3172,curation_candidate,9949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3173,curation_candidate,9982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3174,curation_candidate,9993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3175,curation_candidate,10016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3176,curation_candidate,10034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3177,curation_candidate,10035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3178,curation_candidate,10048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3179,curation_candidate,174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3180,curation_candidate,178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3181,curation_candidate,1271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3182,curation_candidate,1305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3183,curation_candidate,2313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3184,curation_candidate,2821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3185,curation_candidate,2822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3186,curation_candidate,2827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3187,curation_candidate,2881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3188,curation_candidate,3970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3189,curation_candidate,3975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3190,curation_candidate,4016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3191,curation_candidate,4106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3192,curation_candidate,4112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3193,curation_candidate,4122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3194,curation_candidate,4125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3195,curation_candidate,4134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3196,curation_candidate,7885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3197,curation_candidate,7896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3198,curation_candidate,7900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3199,curation_candidate,7902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3200,curation_candidate,7915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3201,curation_candidate,7920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3202,curation_candidate,7921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3203,curation_candidate,7925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3204,curation_candidate,7928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3205,curation_candidate,7932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3206,curation_candidate,7933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3207,curation_candidate,7952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3208,curation_candidate,7965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3209,curation_candidate,7976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3210,curation_candidate,7990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3211,curation_candidate,8008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3212,curation_candidate,8014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3213,curation_candidate,8032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3214,curation_candidate,8037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3215,curation_candidate,8046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3216,curation_candidate,8052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3217,curation_candidate,8067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3218,curation_candidate,8079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3219,curation_candidate,8081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3220,curation_candidate,8099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3221,curation_candidate,8101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3222,curation_candidate,8117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3223,curation_candidate,8124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3224,curation_candidate,8135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3225,curation_candidate,8137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3226,curation_candidate,8140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3227,curation_candidate,8143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3228,curation_candidate,8148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3229,curation_candidate,8155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3230,curation_candidate,8196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3231,curation_candidate,8220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3232,curation_candidate,8245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3233,curation_candidate,8270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3234,curation_candidate,8285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3235,curation_candidate,8314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3236,curation_candidate,8329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3237,curation_candidate,8336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3238,curation_candidate,8358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3239,curation_candidate,8391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3240,curation_candidate,8429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3241,curation_candidate,8441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3242,curation_candidate,8463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3243,curation_candidate,8473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3244,curation_candidate,8483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3245,curation_candidate,8496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3246,curation_candidate,8506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3247,curation_candidate,8527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3248,curation_candidate,8556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3249,curation_candidate,8560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3250,curation_candidate,8563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3251,curation_candidate,9278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3252,curation_candidate,9281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3253,curation_candidate,9283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3254,curation_candidate,9297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3255,curation_candidate,9305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3256,curation_candidate,9318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3257,curation_candidate,9324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3258,curation_candidate,9335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3259,curation_candidate,9339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3260,curation_candidate,9357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3261,curation_candidate,9377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3262,curation_candidate,9382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3263,curation_candidate,10050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3264,curation_candidate,10056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3265,curation_candidate,10134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3266,curation_candidate,10137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3267,curation_candidate,10140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3268,curation_candidate,10143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3269,curation_candidate,10148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3270,curation_candidate,10153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3271,curation_candidate,10156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3272,curation_candidate,10158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3273,curation_candidate,10163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3274,curation_candidate,10167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3275,curation_candidate,10183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3276,curation_candidate,10194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3277,curation_candidate,10224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3278,curation_candidate,1037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3279,curation_candidate,1979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3280,curation_candidate,2384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3281,curation_candidate,2887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3282,curation_candidate,2912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3283,curation_candidate,2917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3284,curation_candidate,4206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3285,curation_candidate,4207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3286,curation_candidate,4210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3287,curation_candidate,4214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3288,curation_candidate,4216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3289,curation_candidate,4223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3290,curation_candidate,4227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3291,curation_candidate,4238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3292,curation_candidate,4240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3293,curation_candidate,4244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3294,curation_candidate,4247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3295,curation_candidate,4253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3296,curation_candidate,4256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3297,curation_candidate,8586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3298,curation_candidate,8592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3299,curation_candidate,8604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3300,curation_candidate,8606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3301,curation_candidate,8641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3302,curation_candidate,8657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3303,curation_candidate,8659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3304,curation_candidate,8693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3305,curation_candidate,8701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3306,curation_candidate,8719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3307,curation_candidate,8720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3308,curation_candidate,8731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3309,curation_candidate,8737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3310,curation_candidate,8739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3311,curation_candidate,8748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3312,curation_candidate,8868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3313,curation_candidate,9407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3314,curation_candidate,9411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3315,curation_candidate,10257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3316,curation_candidate,10298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3317,curation_candidate,1381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3318,curation_candidate,1389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3319,curation_candidate,2467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3320,curation_candidate,2476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3321,curation_candidate,2479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3322,curation_candidate,2488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3323,curation_candidate,2932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3324,curation_candidate,4292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3325,curation_candidate,4304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3326,curation_candidate,4319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3327,curation_candidate,4334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3328,curation_candidate,4339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3329,curation_candidate,4609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3330,curation_candidate,9426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3331,curation_candidate,780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3332,curation_candidate,2500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3333,curation_candidate,2505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3334,curation_candidate,2965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3335,curation_candidate,2986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3336,curation_candidate,4375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3337,curation_candidate,4385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3338,curation_candidate,4391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3339,curation_candidate,4415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3340,curation_candidate,4430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3341,curation_candidate,766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3342,curation_candidate,2538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3343,curation_candidate,2542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3344,curation_candidate,3007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3345,curation_candidate,3012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3346,curation_candidate,3013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3347,curation_candidate,4620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3348,curation_candidate,8977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3349,curation_candidate,9463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3350,curation_candidate,9474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3351,curation_candidate,9479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3352,curation_candidate,9483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3353,curation_candidate,9128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3354,curation_candidate,9500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3355,curation_candidate,9510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3356,curation_candidate,9517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3357,curation_candidate,9523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3358,curation_candidate,1807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3359,curation_candidate,2566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3360,curation_candidate,4492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3361,curation_candidate,8858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3362,curation_candidate,9130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3363,curation_candidate,9536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3364,curation_candidate,9541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3365,curation_candidate,9005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3366,curation_candidate,9012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3367,curation_candidate,9582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3368,curation_candidate,9595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3369,curation_candidate,1814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3370,curation_candidate,2006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3371,curation_candidate,9018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3372,curation_candidate,9612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3373,curation_candidate,9618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3374,curation_candidate,9622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3375,curation_candidate,331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3376,curation_candidate,497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3377,curation_candidate,506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3378,curation_candidate,516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3379,curation_candidate,520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3380,curation_candidate,526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3381,curation_candidate,543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3382,curation_candidate,545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3383,curation_candidate,558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3384,curation_candidate,560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3385,curation_candidate,564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3386,curation_candidate,590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3387,curation_candidate,771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3388,curation_candidate,785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3389,curation_candidate,788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3390,curation_candidate,790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3391,curation_candidate,793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3392,curation_candidate,1004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3393,curation_candidate,1051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3394,curation_candidate,1053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3395,curation_candidate,1061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3396,curation_candidate,1078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3397,curation_candidate,1083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3398,curation_candidate,1088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3399,curation_candidate,1118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3400,curation_candidate,1459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3401,curation_candidate,1460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3402,curation_candidate,1471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3403,curation_candidate,2056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3404,curation_candidate,2059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3405,curation_candidate,2070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3406,curation_candidate,2638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3407,curation_candidate,2643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3408,curation_candidate,2666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3409,curation_candidate,2679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3410,curation_candidate,3048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3411,curation_candidate,3053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3412,curation_candidate,3086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3413,curation_candidate,3117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3414,curation_candidate,3123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3415,curation_candidate,3125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3416,curation_candidate,3128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3417,curation_candidate,3141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3418,curation_candidate,3199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3419,curation_candidate,3203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3420,curation_candidate,3213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3421,curation_candidate,3229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3422,curation_candidate,3238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3423,curation_candidate,3240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3424,curation_candidate,3242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3425,curation_candidate,3244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3426,curation_candidate,3258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3427,curation_candidate,3260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3428,curation_candidate,3264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3429,curation_candidate,3277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3430,curation_candidate,3282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3431,curation_candidate,3284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3432,curation_candidate,3286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3433,curation_candidate,3287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3434,curation_candidate,3294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3435,curation_candidate,3301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3436,curation_candidate,3315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3437,curation_candidate,3330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3438,curation_candidate,3335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3439,curation_candidate,3346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3440,curation_candidate,3349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3441,curation_candidate,3356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3442,curation_candidate,4646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3443,curation_candidate,4670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3444,curation_candidate,4673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3445,curation_candidate,4676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3446,curation_candidate,4678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3447,curation_candidate,4680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3448,curation_candidate,4700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3449,curation_candidate,4702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3450,curation_candidate,4714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3451,curation_candidate,4731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3452,curation_candidate,4746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3453,curation_candidate,4748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3454,curation_candidate,4750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3455,curation_candidate,4752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3456,curation_candidate,4765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3457,curation_candidate,4781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3458,curation_candidate,4795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3459,curation_candidate,4800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3460,curation_candidate,4804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3461,curation_candidate,4808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3462,curation_candidate,4820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3463,curation_candidate,4821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3464,curation_candidate,4825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3465,curation_candidate,4840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3466,curation_candidate,4846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3467,curation_candidate,4851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3468,curation_candidate,4876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3469,curation_candidate,4878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3470,curation_candidate,4881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3471,curation_candidate,4882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3472,curation_candidate,4889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3473,curation_candidate,4892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3474,curation_candidate,4895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3475,curation_candidate,4900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3476,curation_candidate,4906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3477,curation_candidate,4913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3478,curation_candidate,4914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3479,curation_candidate,4919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3480,curation_candidate,4927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3481,curation_candidate,4944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3482,curation_candidate,4947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3483,curation_candidate,4949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3484,curation_candidate,4968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3485,curation_candidate,4994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3486,curation_candidate,4996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3487,curation_candidate,5004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3488,curation_candidate,5013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3489,curation_candidate,5032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3490,curation_candidate,5034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3491,curation_candidate,5048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3492,curation_candidate,5055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3493,curation_candidate,5064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3494,curation_candidate,5078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3495,curation_candidate,5085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3496,curation_candidate,5087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3497,curation_candidate,5108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3498,curation_candidate,5118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3499,curation_candidate,5134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3500,curation_candidate,5179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3501,curation_candidate,5183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3502,curation_candidate,5185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3503,curation_candidate,5187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3504,curation_candidate,5235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3505,curation_candidate,5238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3506,curation_candidate,5274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3507,curation_candidate,5277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3508,curation_candidate,5290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3509,curation_candidate,5294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3510,curation_candidate,5296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3511,curation_candidate,5321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3512,curation_candidate,5347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3513,curation_candidate,5355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3514,curation_candidate,5381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3515,curation_candidate,5388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3516,curation_candidate,5410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3517,curation_candidate,5422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3518,curation_candidate,5443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3519,curation_candidate,5447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3520,curation_candidate,5473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3521,curation_candidate,5476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3522,curation_candidate,5479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3523,curation_candidate,5482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3524,curation_candidate,5486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3525,curation_candidate,5489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3526,curation_candidate,5499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3527,curation_candidate,5501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3528,curation_candidate,5503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3529,curation_candidate,5505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3530,curation_candidate,5514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3531,curation_candidate,5536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3532,curation_candidate,5550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3533,curation_candidate,5554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3534,curation_candidate,5558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3535,curation_candidate,5569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3536,curation_candidate,5572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3537,curation_candidate,5574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3538,curation_candidate,5585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3539,curation_candidate,5590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3540,curation_candidate,5596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3541,curation_candidate,5599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3542,curation_candidate,5608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3543,curation_candidate,5613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3544,curation_candidate,5622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3545,curation_candidate,5623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3546,curation_candidate,5651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3547,curation_candidate,5655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3548,curation_candidate,5667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3549,curation_candidate,5686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3550,curation_candidate,5689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3551,curation_candidate,5694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3552,curation_candidate,5699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3553,curation_candidate,5710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3554,curation_candidate,5714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3555,curation_candidate,5719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3556,curation_candidate,5723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3557,curation_candidate,5731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3558,curation_candidate,5749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3559,curation_candidate,5752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3560,curation_candidate,5762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3561,curation_candidate,5770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3562,curation_candidate,5784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3563,curation_candidate,5788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3564,curation_candidate,5790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3565,curation_candidate,5797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3566,curation_candidate,5800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3567,curation_candidate,5815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3568,curation_candidate,5821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3569,curation_candidate,5826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3570,curation_candidate,5832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3571,curation_candidate,5838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3572,curation_candidate,5843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3573,curation_candidate,5866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3574,curation_candidate,5872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3575,curation_candidate,5884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3576,curation_candidate,5889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3577,curation_candidate,5896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3578,curation_candidate,5911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3579,curation_candidate,5937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3580,curation_candidate,5960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3581,curation_candidate,5964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3582,curation_candidate,5968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3583,curation_candidate,5990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3584,curation_candidate,6003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3585,curation_candidate,6007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3586,curation_candidate,6015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3587,curation_candidate,6019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3588,curation_candidate,6039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3589,curation_candidate,6055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3590,curation_candidate,9137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3591,curation_candidate,9140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3592,curation_candidate,9142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3593,curation_candidate,9144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3594,curation_candidate,9146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3595,curation_candidate,9645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3596,curation_candidate,9680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3597,curation_candidate,9692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3598,curation_candidate,9694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3599,curation_candidate,9698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3600,curation_candidate,9701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3601,curation_candidate,142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3602,curation_candidate,148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3603,curation_candidate,400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3604,curation_candidate,825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3605,curation_candidate,830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3606,curation_candidate,851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3607,curation_candidate,1179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3608,curation_candidate,1847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3609,curation_candidate,1856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3610,curation_candidate,1863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3611,curation_candidate,1964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3612,curation_candidate,2123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3613,curation_candidate,2140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3614,curation_candidate,2148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3615,curation_candidate,2170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3616,curation_candidate,2213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3617,curation_candidate,2224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3618,curation_candidate,2225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3619,curation_candidate,2255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3620,curation_candidate,2261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3621,curation_candidate,2763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3622,curation_candidate,2783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3623,curation_candidate,2808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3624,curation_candidate,3383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3625,curation_candidate,3426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3626,curation_candidate,3431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3627,curation_candidate,3451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3628,curation_candidate,3453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3629,curation_candidate,3458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3630,curation_candidate,3468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3631,curation_candidate,3501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3632,curation_candidate,3502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3633,curation_candidate,3540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3634,curation_candidate,3542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3635,curation_candidate,3546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3636,curation_candidate,3567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3637,curation_candidate,3569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3638,curation_candidate,3579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3639,curation_candidate,3585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3640,curation_candidate,3597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3641,curation_candidate,3598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3642,curation_candidate,3616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3643,curation_candidate,3623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3644,curation_candidate,3629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3645,curation_candidate,3631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3646,curation_candidate,3644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3647,curation_candidate,3665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3648,curation_candidate,3667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3649,curation_candidate,3702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3650,curation_candidate,3706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3651,curation_candidate,3720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3652,curation_candidate,3731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3653,curation_candidate,3738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3654,curation_candidate,3741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3655,curation_candidate,3749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3656,curation_candidate,3762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3657,curation_candidate,3769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3658,curation_candidate,3771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3659,curation_candidate,3776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3660,curation_candidate,3810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3661,curation_candidate,3824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3662,curation_candidate,3837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3663,curation_candidate,3840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3664,curation_candidate,3845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3665,curation_candidate,3857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3666,curation_candidate,3859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3667,curation_candidate,3868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3668,curation_candidate,3881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3669,curation_candidate,3896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3670,curation_candidate,3898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3671,curation_candidate,3915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3672,curation_candidate,3931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3673,curation_candidate,3934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3674,curation_candidate,3957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3675,curation_candidate,6063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3676,curation_candidate,6117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3677,curation_candidate,6124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3678,curation_candidate,6140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3679,curation_candidate,6211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3680,curation_candidate,6261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3681,curation_candidate,6296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3682,curation_candidate,6302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3683,curation_candidate,6352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3684,curation_candidate,6368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3685,curation_candidate,6399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3686,curation_candidate,6403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3687,curation_candidate,6410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3688,curation_candidate,6419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3689,curation_candidate,6433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3690,curation_candidate,6434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3691,curation_candidate,6457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3692,curation_candidate,6465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3693,curation_candidate,6491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3694,curation_candidate,6503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3695,curation_candidate,6521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3696,curation_candidate,6524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3697,curation_candidate,6530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3698,curation_candidate,6582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3699,curation_candidate,6607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3700,curation_candidate,6610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3701,curation_candidate,6616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3702,curation_candidate,6646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3703,curation_candidate,6656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3704,curation_candidate,6657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3705,curation_candidate,6661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3706,curation_candidate,6667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3707,curation_candidate,6680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3708,curation_candidate,6687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3709,curation_candidate,6695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3710,curation_candidate,6700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3711,curation_candidate,6702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3712,curation_candidate,6707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3713,curation_candidate,6729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3714,curation_candidate,6755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3715,curation_candidate,6759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3716,curation_candidate,6795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3717,curation_candidate,6813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3718,curation_candidate,6817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3719,curation_candidate,6824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3720,curation_candidate,6827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3721,curation_candidate,6864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3722,curation_candidate,6891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3723,curation_candidate,6904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3724,curation_candidate,6919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3725,curation_candidate,6921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3726,curation_candidate,6934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3727,curation_candidate,6940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3728,curation_candidate,6948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3729,curation_candidate,6966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3730,curation_candidate,6986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3731,curation_candidate,6991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3732,curation_candidate,7010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3733,curation_candidate,7020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3734,curation_candidate,7023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3735,curation_candidate,7025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3736,curation_candidate,7027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3737,curation_candidate,7031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3738,curation_candidate,7061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3739,curation_candidate,7064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3740,curation_candidate,7068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3741,curation_candidate,7095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3742,curation_candidate,7097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3743,curation_candidate,7111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3744,curation_candidate,7128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3745,curation_candidate,7135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3746,curation_candidate,7139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3747,curation_candidate,7147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3748,curation_candidate,7151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3749,curation_candidate,7166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3750,curation_candidate,7178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3751,curation_candidate,7196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3752,curation_candidate,7223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3753,curation_candidate,7233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3754,curation_candidate,7238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3755,curation_candidate,7248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3756,curation_candidate,7253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3757,curation_candidate,7272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3758,curation_candidate,7289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3759,curation_candidate,7301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3760,curation_candidate,7303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3761,curation_candidate,7317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3762,curation_candidate,7328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3763,curation_candidate,7349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3764,curation_candidate,7411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3765,curation_candidate,7416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3766,curation_candidate,7420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3767,curation_candidate,7425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3768,curation_candidate,7434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3769,curation_candidate,7507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3770,curation_candidate,7596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3771,curation_candidate,7622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3772,curation_candidate,7630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3773,curation_candidate,7644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3774,curation_candidate,7654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3775,curation_candidate,7657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3776,curation_candidate,7665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3777,curation_candidate,7681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3778,curation_candidate,7698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3779,curation_candidate,7705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3780,curation_candidate,7707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3781,curation_candidate,7708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3782,curation_candidate,7730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3783,curation_candidate,7737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3784,curation_candidate,7741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3785,curation_candidate,7746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3786,curation_candidate,7750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3787,curation_candidate,7760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3788,curation_candidate,7769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3789,curation_candidate,7771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3790,curation_candidate,7783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3791,curation_candidate,7800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3792,curation_candidate,7804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3793,curation_candidate,7810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3794,curation_candidate,7821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3795,curation_candidate,7823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3796,curation_candidate,7826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3797,curation_candidate,7844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3798,curation_candidate,7869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3799,curation_candidate,7874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3800,curation_candidate,8831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3801,curation_candidate,8890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3802,curation_candidate,8909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3803,curation_candidate,9040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3804,curation_candidate,9041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3805,curation_candidate,9055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3806,curation_candidate,9058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3807,curation_candidate,9166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3808,curation_candidate,9170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3809,curation_candidate,9180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3810,curation_candidate,9191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3811,curation_candidate,9192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3812,curation_candidate,9197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3813,curation_candidate,9226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3814,curation_candidate,9229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3815,curation_candidate,9239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3816,curation_candidate,9243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3817,curation_candidate,9247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3818,curation_candidate,9249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3819,curation_candidate,9255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3820,curation_candidate,9257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3821,curation_candidate,9265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3822,curation_candidate,9270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3823,curation_candidate,9726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3824,curation_candidate,9742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3825,curation_candidate,9750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3826,curation_candidate,9753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3827,curation_candidate,9759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3828,curation_candidate,9763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3829,curation_candidate,9768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3830,curation_candidate,9769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3831,curation_candidate,9774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3832,curation_candidate,9777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3833,curation_candidate,9799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3834,curation_candidate,9807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3835,curation_candidate,9808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3836,curation_candidate,9820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3837,curation_candidate,9836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3838,curation_candidate,9839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3839,curation_candidate,9854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3840,curation_candidate,9864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3841,curation_candidate,9889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3842,curation_candidate,9890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3843,curation_candidate,9894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3844,curation_candidate,9913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3845,curation_candidate,9915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3846,curation_candidate,9936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3847,curation_candidate,9955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3848,curation_candidate,9986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3849,curation_candidate,9996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3850,curation_candidate,10000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3851,curation_candidate,10003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3852,curation_candidate,10015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3853,curation_candidate,10026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3854,curation_candidate,10041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3855,curation_candidate,871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3856,curation_candidate,906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3857,curation_candidate,1282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3858,curation_candidate,1302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3859,curation_candidate,1868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3860,curation_candidate,2298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3861,curation_candidate,2329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3862,curation_candidate,2826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3863,curation_candidate,2858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3864,curation_candidate,3987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3865,curation_candidate,4000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3866,curation_candidate,4003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3867,curation_candidate,4021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3868,curation_candidate,4024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3869,curation_candidate,4056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3870,curation_candidate,4060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3871,curation_candidate,4068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3872,curation_candidate,4076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3873,curation_candidate,4080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3874,curation_candidate,4088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3875,curation_candidate,4093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3876,curation_candidate,4099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3877,curation_candidate,4117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3878,curation_candidate,4127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3879,curation_candidate,4132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3880,curation_candidate,4140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3881,curation_candidate,4143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3882,curation_candidate,4151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3883,curation_candidate,7944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3884,curation_candidate,7959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3885,curation_candidate,7968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3886,curation_candidate,7979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3887,curation_candidate,8005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3888,curation_candidate,8006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3889,curation_candidate,8021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3890,curation_candidate,8033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3891,curation_candidate,8074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3892,curation_candidate,8105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3893,curation_candidate,8111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3894,curation_candidate,8165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3895,curation_candidate,8201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3896,curation_candidate,8238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3897,curation_candidate,8252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3898,curation_candidate,8287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3899,curation_candidate,8298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3900,curation_candidate,8328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3901,curation_candidate,8337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3902,curation_candidate,8344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3903,curation_candidate,8372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3904,curation_candidate,8376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3905,curation_candidate,8378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3906,curation_candidate,8386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3907,curation_candidate,8387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3908,curation_candidate,8419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3909,curation_candidate,8433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3910,curation_candidate,8451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3911,curation_candidate,8456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3912,curation_candidate,8486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3913,curation_candidate,8520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3914,curation_candidate,8522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3915,curation_candidate,8531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3916,curation_candidate,8552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3917,curation_candidate,8558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3918,curation_candidate,8921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3919,curation_candidate,9074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3920,curation_candidate,9083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3921,curation_candidate,9288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3922,curation_candidate,9303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3923,curation_candidate,9307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3924,curation_candidate,9311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3925,curation_candidate,9313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3926,curation_candidate,9315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3927,curation_candidate,9326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3928,curation_candidate,9332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3929,curation_candidate,9344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3930,curation_candidate,9355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3931,curation_candidate,9360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3932,curation_candidate,9375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3933,curation_candidate,9379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3934,curation_candidate,10081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3935,curation_candidate,10089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3936,curation_candidate,10090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3937,curation_candidate,10094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope non-therapeutic or non-human oligonucleotide context,2026-06-02T14:37:29+00:00
3938,curation_candidate,10096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3939,curation_candidate,10104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3940,curation_candidate,10124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3941,curation_candidate,10161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3942,curation_candidate,10169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3943,curation_candidate,10178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3944,curation_candidate,10190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3945,curation_candidate,10193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3946,curation_candidate,10237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3947,curation_candidate,1344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3948,curation_candidate,1377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3949,curation_candidate,1785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3950,curation_candidate,2413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3951,curation_candidate,2426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3952,curation_candidate,2428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3953,curation_candidate,4193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3954,curation_candidate,4212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3955,curation_candidate,4220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3956,curation_candidate,4229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3957,curation_candidate,4236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3958,curation_candidate,4272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3959,curation_candidate,4274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3960,curation_candidate,4276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3961,curation_candidate,4607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3962,curation_candidate,8634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3963,curation_candidate,8647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3964,curation_candidate,8649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3965,curation_candidate,8664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3966,curation_candidate,8677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3967,curation_candidate,8686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3968,curation_candidate,8695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3969,curation_candidate,8710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3970,curation_candidate,8711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3971,curation_candidate,8712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3972,curation_candidate,8717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3973,curation_candidate,8942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3974,curation_candidate,9385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3975,curation_candidate,9399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3976,curation_candidate,9419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3977,curation_candidate,10274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3978,curation_candidate,10279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3979,curation_candidate,10297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3980,curation_candidate,10299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3981,curation_candidate,1405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3982,curation_candidate,1408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3983,curation_candidate,1981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3984,curation_candidate,1987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3985,curation_candidate,4311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3986,curation_candidate,4325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3987,curation_candidate,4330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
3988,curation_candidate,4344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3989,curation_candidate,9425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3990,curation_candidate,973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3991,curation_candidate,1419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3992,curation_candidate,1526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3993,curation_candidate,1897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3994,curation_candidate,2502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3995,curation_candidate,2509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3996,curation_candidate,2970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3997,curation_candidate,4371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review or background article, not primary oligonucleotide toxicity evidence",2026-06-02T14:37:29+00:00
3998,curation_candidate,4387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
3999,curation_candidate,4393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4000,curation_candidate,4399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4001,curation_candidate,4402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
4002,curation_candidate,4410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4003,curation_candidate,4418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4004,curation_candidate,4425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
4005,curation_candidate,9441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4006,curation_candidate,9445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4007,curation_candidate,9453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4008,curation_candidate,2545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4009,curation_candidate,2991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4010,curation_candidate,3002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4011,curation_candidate,3003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4012,curation_candidate,3004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4013,curation_candidate,3014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4014,curation_candidate,3021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
4015,curation_candidate,3022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4016,curation_candidate,4454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4017,curation_candidate,9457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4018,curation_candidate,4483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: source context is disease biology or therapeutic efficacy, not primary oligonucleotide safety evidence",2026-06-02T14:37:29+00:00
4019,curation_candidate,8987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4020,curation_candidate,8991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4021,curation_candidate,9488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4022,curation_candidate,9490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4023,curation_candidate,9493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support primary oligonucleotide toxicity evidence,2026-06-02T14:37:29+00:00
4024,offtarget_evidence,57,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Transcriptomic profiling reveals HPV16 E7-mediated regulation of Wnt/β-catenin signaling and APC2 expression in cervical cancer; paragraph 23: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4025,offtarget_evidence,58,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at article body; paragraph 6: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4026,offtarget_evidence,59,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > RNP delivery reduces transcriptome-wide off-target editing; paragraph 22: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4027,offtarget_evidence,60,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Minimal off-target activity of GalNAc-siCIDEB; paragraph 8: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4028,offtarget_evidence,61,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Identification of potent and specific transgene regulator siRNAs; paragraph 29: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4029,offtarget_evidence,62,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Impact of GNA isonucleotides on GalNAc-siRNA in vitro activity; paragraph 49: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4030,offtarget_evidence,63,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Transcriptome-wide analyses of mi/siRNAs targeting E6/E7; paragraph 17: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4031,offtarget_evidence,64,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Di-siRNA modulates HTT expression with minimal off-target events; paragraph 33: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4032,offtarget_evidence,65,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Hybridization-dependent toxicity is not likely to account for the 2′ F PS-ASO-induced hepatotoxicity; Figure 5. caption: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4033,offtarget_evidence,66,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > High Confirmation Rate of In Silico Predicted OTEs in Mouse Liver; paragraph 14: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4034,offtarget_evidence,67,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Hepatotoxicity of LNA ASOs is RNase H1 dependent; paragraph 35: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4035,offtarget_evidence,68,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4036,offtarget_evidence,69,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4037,offtarget_evidence,70,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4038,offtarget_evidence,71,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 8: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4039,offtarget_evidence,72,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4040,offtarget_evidence,73,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4041,offtarget_evidence,74,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4042,offtarget_evidence,75,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4043,offtarget_evidence,76,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4044,offtarget_evidence,77,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4045,offtarget_evidence,78,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASO off-target RNA reduction correlates well with off-target protein reduction in HepG2 cells; paragraph 48: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4046,offtarget_evidence,79,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ClinASO enables efficient identification of potent ASO against PCSK9; paragraph 12: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4047,offtarget_evidence,80,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Fluorescent in situ hybridization in patient-derived NSCs; paragraph 16: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4048,offtarget_evidence,81,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4049,offtarget_evidence,82,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > IGF2BP2 Knockdown promotes ferroptosis in HNSCC via reduced NRF2 mRNA stability; paragraph 10: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4050,offtarget_evidence,83,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4051,offtarget_evidence,84,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > In vitro on-/off-target assessment in human cells; paragraph 8: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4052,offtarget_evidence,85,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Supplementary Information; paragraph 48: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4053,offtarget_evidence,86,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Single-cell transcriptome profiling demonstrates marked effects of LNA-modified FXR1 siRNA on tumor growth inhibition and anti-tumor immune responses; paragraph 24: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4054,offtarget_evidence,87,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at article body; paragraph 14: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4055,offtarget_evidence,88,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Effect of tetra-siRNAS6k1 on phospholipids is conserved between mouse and pig; paragraph 16: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4056,offtarget_evidence,89,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > UTMD-Loaded si-JMJD2A induces ferroptosis and inhibits ESCC cell proliferation in vitro; paragraph 26: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4057,offtarget_evidence,90,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > siRNA targeting FGFR2 significantly modulates the FGFR2-related osteogenic cascade in CS patients’ cells; Figure 2 caption: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4058,offtarget_evidence,91,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Screening of SNA-modified siRNAs targeting CAG repeats; paragraph 8: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4059,offtarget_evidence,92,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.3. Functional Role of TEAD4 in PSC Proliferation and Myogenic Differentiation; paragraph 20: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4060,offtarget_evidence,93,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4061,offtarget_evidence,94,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RNA-Targeted Therapeutics for Lipid-Metabolic Disorders: Bench Evidence; paragraph 35: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4062,offtarget_evidence,95,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4063,offtarget_evidence,96,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Combined depletion of NADK and NADK2 caused lethality in human cells; paragraph 7: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4064,offtarget_evidence,97,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > KCC07 induced apoptosis and inhibited CRC cell proliferation both in vitro and in vivo; paragraph 35: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4065,offtarget_evidence,98,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4066,offtarget_evidence,99,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4067,offtarget_evidence,100,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Screening antiviral activity and tolerability of siRNA candidates in a high-throughput SARS-CoV-2 infection model; paragraph 38: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4068,offtarget_evidence,101,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4069,offtarget_evidence,102,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4070,offtarget_evidence,103,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Inhaled T7-EV/siTGF-β1 Alleviates Bleomycin-Induced Pulmonary Fibrosis in vivo; paragraph 51: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4071,offtarget_evidence,104,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4072,offtarget_evidence,105,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 4. Viruses in Cancer Research and Gene-Silencing Experiments During RNA Virus Infection > 4.3. Viruses in the Context of siRNA Knockdown—Analogous Scenarios to the Ambati et al. [1] Postulate > 4.3.1. Silencing of the DNA MMR During Influenza Infection via Chimeric Viruses; paragraph 84: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4073,offtarget_evidence,106,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Inhibition of FABP4 induces mitochondrial dysfunction in trophoblast cells; paragraph 41: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4074,offtarget_evidence,107,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 2: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4075,offtarget_evidence,108,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > The MRTF/SRF pathway is activated in endometriosis and controlled by CRMP4; paragraph 37: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4076,offtarget_evidence,109,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4077,offtarget_evidence,110,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 4. Results > 4.1. Model Validation and Characterization of General Tissue Distribution; paragraph 20: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4078,offtarget_evidence,111,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 6: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4079,offtarget_evidence,112,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Human B-NHL treated with WAS siRNA-loaded NPs attenuates tumor growth in vivo; paragraph 21: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4080,offtarget_evidence,113,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > In silico off-target analysis and qPCR validation; paragraph 10: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4081,offtarget_evidence,114,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4082,offtarget_evidence,115,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.4. Gene Silencing Effect of Chemically Modified siRNAs; paragraph 14: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4083,offtarget_evidence,116,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Characterization of off-target activities of bsYW-61; paragraph 14: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4084,offtarget_evidence,117,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4085,offtarget_evidence,118,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4086,offtarget_evidence,119,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4087,offtarget_evidence,120,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 12: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4088,offtarget_evidence,121,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.2. Data Analysis > 2.2.3. Sequence Analysis; paragraph 12: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4089,offtarget_evidence,122,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Positional effects of base type and ΔEi levels on siRNA activity; paragraph 18: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4090,offtarget_evidence,123,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4091,offtarget_evidence,124,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PD-L1-targeting aptamer-siRNA chimera selectively targets intratumoral Treg cells and induces effective CD47 silencing; paragraph 9: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4092,offtarget_evidence,125,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Conjoint Analyses of scRNA‐seq and m5C‐seq Reveal the Crucial Role of NSUN4 in Regulating CD8+T Cell Exhaustion; FIGURE 6 caption: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4093,offtarget_evidence,126,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4094,offtarget_evidence,127,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > The knockdown efficacy of asiRNAs is similar to that of symmetric siRNAs; paragraph 36: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4095,offtarget_evidence,128,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4096,offtarget_evidence,129,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4097,offtarget_evidence,130,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Dual-color fluorescence in situ hybridization; paragraph 18: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4098,offtarget_evidence,131,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4099,offtarget_evidence,132,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 2: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4100,offtarget_evidence,133,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Endogenous RNA degradation by STAR; paragraph 21: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4101,offtarget_evidence,134,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 2: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4102,offtarget_evidence,135,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Transcriptomic analyses of BHF7-transfected vSMCs demonstrates expected changes to known SMILR regulated genes without apparent toxic effect; paragraph 43: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4103,offtarget_evidence,136,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4104,offtarget_evidence,137,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4105,offtarget_evidence,138,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Inverted MYC/KRAS chimeras synergistically target KRAS mutant cancers.; paragraph 24: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4106,offtarget_evidence,139,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > NEAT1 is upregulated in nasal polyps and promotes EMT in nasal epithelial cells; paragraph 33: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4107,offtarget_evidence,140,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > A genome-wide CRISPR/Cas9 Screen identifies novel factors contributing to TLR3 signaling; Figure 1 caption: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4108,offtarget_evidence,141,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at SAMS application: in vivo siRNA delivery in murine cancer models; paragraph 39: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4109,offtarget_evidence,142,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Overexpression of Zfp36 in senescent macrophages promotes IL-27 p28 mRNA degradation and inhibits IL-27 signaling; paragraph 16: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4110,offtarget_evidence,143,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4111,offtarget_evidence,144,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4112,offtarget_evidence,145,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4113,offtarget_evidence,146,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4114,offtarget_evidence,147,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4115,offtarget_evidence,148,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and Methods > Single cell RNA sequencing (scRNA-seq); paragraph 23: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4116,offtarget_evidence,149,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4117,offtarget_evidence,150,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4118,offtarget_evidence,151,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Designing new shRNAs to target the CAG tract; paragraph 9: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4119,offtarget_evidence,152,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Over-representation analyses of transcriptome changes following COP1 suppression in transformed and primary hepatocytes; paragraph 22: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4120,offtarget_evidence,153,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Modified R-ASOs retain readthrough activity and reduce mRNA degradation; paragraph 39: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4121,offtarget_evidence,154,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4122,offtarget_evidence,155,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Screening of REST_SSO; paragraph 6: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4124,offtarget_evidence,157,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 9: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4125,offtarget_evidence,158,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; Figure 7 caption: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4126,offtarget_evidence,159,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3 Results > 3.5 OligoFormer with off-target searching for siRNA design; paragraph 31: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4127,offtarget_evidence,160,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4128,offtarget_evidence,161,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.1. Design and Verification of siRNAs Targeting Highly Conserved Regions of SARS-CoV-2; paragraph 17: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4129,offtarget_evidence,162,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Derivation and stability of recombinant S. typhimurium SL7207; paragraph 9: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4130,offtarget_evidence,163,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Identification of multispecies-targeting siRNAs that efficiently silence JAK1 across various species; paragraph 8: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4131,offtarget_evidence,164,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PH-762 is a stabilized self-delivering siRNA compound designed to potently silence PDCD1 mRNA with high specificity; paragraph 10: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4132,offtarget_evidence,165,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > The effects of Sema5a suppression on male cortical development; paragraph 54: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4133,offtarget_evidence,166,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Map1a knockdown (KD) by RNAi perturbs the Sertoli cell TJ barrier due to the disruptive distribution of TJ and basal ES proteins; paragraph 22: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4134,offtarget_evidence,167,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4135,offtarget_evidence,168,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Identification of a highly specific GPR68 inhibitor; paragraph 30: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4136,offtarget_evidence,169,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4137,offtarget_evidence,170,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at 3 Results > 3.4 Inhibition of the productive Fin-3 SARS-CoV-2 infection in VE6-T2 cells by the chimeric, 3′UTR, NSP1, NSP2, and NSP12 DsiRNA swarms; paragraph 29: primary offtarget support for off-target evidence in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4138,offtarget_evidence,171,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > C9ORF72 repeat-containing and non-repeat-containing isoforms form nuclear clusters in astrocytes derived from C9-ALS/FTD mice; paragraph 23: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4139,offtarget_evidence,172,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4140,offtarget_evidence,173,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.6. In Silico Analysis of the Sequence-Dependent Off-Target Effects of LNA Gapmers; paragraph 17: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4141,offtarget_evidence,174,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4142,offtarget_evidence,175,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Off-target minimization; paragraph 17: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4143,offtarget_evidence,176,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Local administration of si3033 reduces skin infiltration of autoreactive CD8+ T cells and prevents skin depigmentation in a mouse model of vitiligo; paragraph 15: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4144,offtarget_evidence,177,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > AOC-mediated activity is amenable to various types of oligonucleotide chemistry; Figure 6. caption: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4145,offtarget_evidence,178,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Intramuscular delivery of siRNAs using RBCEVs is non-toxic and non-inflammatory; paragraph 22: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4146,offtarget_evidence,179,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4147,offtarget_evidence,180,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4148,offtarget_evidence,181,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results: > Photoreceptor-specific targeted RNAi screen reveals transcription elongation factors are necessary for age-dependent photoreceptor survival; paragraph 8: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4149,offtarget_evidence,182,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4150,offtarget_evidence,183,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4151,offtarget_evidence,184,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Reversal of chemoresistance by siRNA gene silencing; paragraph 11: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4152,offtarget_evidence,185,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 3: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4153,offtarget_evidence,186,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > AsNIP43 knockdown impaired rhizobial infection and nodulation while AsNIP43 overexpression increased nodule number; paragraph 24: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4154,offtarget_evidence,187,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4155,offtarget_evidence,188,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Transcriptomics and proteomics analysis of modified CT102s; paragraph 23: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4156,offtarget_evidence,189,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4157,offtarget_evidence,190,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Off-target effect analysis; paragraph 18: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4158,offtarget_evidence,191,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > DLin-MC3-DMA conjugate enhances tissue retention and promotes broad distribution; paragraph 28: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4159,offtarget_evidence,192,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > SLN360 Specifically Downregulates LPA in Primary Hepatocytes; paragraph 28: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4160,offtarget_evidence,193,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Indirect FXN activation is unlikely to be mediated by a mutual hybridization-dependent off-target transcript; paragraph 49: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4161,offtarget_evidence,194,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PK-modifying anchors allow efficient modulation of blood circulating times and biodistribution of chemically distinct siRNA conjugates; paragraph 15: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4162,offtarget_evidence,195,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Effects of MT1 and/or MT2 Vivo-Morpholino on liver phenotypes of BDL and Mdr2−/− mice; paragraph 22: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4163,offtarget_evidence,196,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.6. LNP-si-LINC01257 Impairs Kasumi-1 Cell Proliferation without Affecting Healthy PBMCs; paragraph 29: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4164,offtarget_evidence,197,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Screening the optimal UNA position in CAG-siRNAs with a luciferase-ATXN3 reporter assay; paragraph 7: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4165,offtarget_evidence,198,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Potential for Animal Off-Targeting by ‘HoneySweet’ sRNA Species; paragraph 39: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4166,offtarget_evidence,199,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.5. Cellular Uptake and Subcellular Distribution of Dual-RGD Carrier; paragraph 26: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4167,offtarget_evidence,200,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Tracking and visualization of the delivery of self-assembled mHTT siRNA into the cortex and striatum; Figure 3 caption: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4168,offtarget_evidence,201,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS AND DISCUSSION > On-target and off-target activities of siRNAs modified with 2′-F-NMC; paragraph 42: primary offtarget support for seed-mediated off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4169,offtarget_evidence,202,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4170,offtarget_evidence,203,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4171,offtarget_evidence,204,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4172,offtarget_evidence,205,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4173,offtarget_evidence,206,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > CDK9 Inhibition Leads to a Synergistic Loss of Ewing Sarcoma Cell Viability When Combined with Mithramycin; paragraph 18: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4174,offtarget_evidence,207,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASOs targeting human mRNAs can also induce a type I IFN response in cultured THP1 cells; paragraph 31: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4175,offtarget_evidence,208,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Liver-Targeted RNAi With GalNac-MASP-2 Duplex Robustly Silences C4b Deposition by the LP; paragraph 35: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4176,offtarget_evidence,209,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4177,offtarget_evidence,210,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4178,offtarget_evidence,211,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4179,offtarget_evidence,212,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Hybridization Properties of µ-ODNs Targeting miR-21.; paragraph 11: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4180,offtarget_evidence,213,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Impact of fatty acid conjugate valency on siRNA tissue distribution profile.; paragraph 20: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4181,offtarget_evidence,214,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Cy3 dye has no major impact on tissue distribution profile of lipid-conjugated siRNA; paragraph 25: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4182,offtarget_evidence,215,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > CMTM4 expression is essential for vascular growth in an in vitro 3D angiogenesis assay; paragraph 23: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4183,offtarget_evidence,216,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at article body; paragraph 2: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4184,offtarget_evidence,217,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > QR-110 Treatment Reduces Aberrant Splicing, Increases Wild-Type CEP290 in Homozygous Retinal Organoids, and Shows No Off-Target Pharmacology; paragraph 15: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4185,offtarget_evidence,218,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Gross and Anatomic Pathology; paragraph 42: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4186,offtarget_evidence,219,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4187,offtarget_evidence,220,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Off-target knockdown by the Acsl1 gapmer; paragraph 15: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4188,offtarget_evidence,221,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > LNA-i-miR-221 is detectable in xenografted tumors and mouse organs by in situ hybridization; paragraph 5: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4189,offtarget_evidence,222,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 9: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4190,offtarget_evidence,223,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4191,offtarget_evidence,224,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > AMO specificity; paragraph 33: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4192,offtarget_evidence,225,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Mismatch-specific EGFP Correction; Figure 1 caption: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4193,offtarget_evidence,226,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4194,offtarget_evidence,227,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 5: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4195,offtarget_evidence,228,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4196,offtarget_evidence,229,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4197,offtarget_evidence,230,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4198,offtarget_evidence,231,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4199,offtarget_evidence,232,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4200,offtarget_evidence,233,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4201,offtarget_evidence,234,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4202,offtarget_evidence,235,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4203,offtarget_evidence,236,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4204,offtarget_evidence,237,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4205,offtarget_evidence,238,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4206,offtarget_evidence,239,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4207,offtarget_evidence,240,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4208,offtarget_evidence,241,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4209,offtarget_evidence,242,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4210,offtarget_evidence,243,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4211,offtarget_evidence,244,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4212,offtarget_evidence,245,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4213,offtarget_evidence,246,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4214,offtarget_evidence,247,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4215,offtarget_evidence,248,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4216,offtarget_evidence,249,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4217,offtarget_evidence,250,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4218,offtarget_evidence,251,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 2: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4219,offtarget_evidence,252,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4220,offtarget_evidence,253,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4221,offtarget_evidence,254,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4222,offtarget_evidence,255,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4223,offtarget_evidence,256,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4224,offtarget_evidence,257,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 4: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4225,offtarget_evidence,258,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4226,offtarget_evidence,259,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4227,offtarget_evidence,260,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4228,offtarget_evidence,261,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4229,offtarget_evidence,262,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4230,offtarget_evidence,263,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4231,offtarget_evidence,264,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4232,offtarget_evidence,265,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4233,offtarget_evidence,266,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4234,offtarget_evidence,267,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4235,offtarget_evidence,268,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4236,offtarget_evidence,269,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4237,offtarget_evidence,270,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4238,offtarget_evidence,271,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for transcriptome-level off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4239,offtarget_evidence,272,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4240,offtarget_evidence,273,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for hybridization/mismatch off-target effect in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4241,offtarget_evidence,274,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary offtarget support for off-target evidence in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4242,toxicity_endpoint,475,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety evaluation; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4243,toxicity_endpoint,476,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety characterization and IND-enabling studies; paragraph 15: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4244,toxicity_endpoint,477,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 24: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4245,toxicity_endpoint,478,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > F-ASO gapmers reduce disease-associated repeat RNA foci in patient-derived NSCs; paragraph 32: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4246,toxicity_endpoint,479,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > In Vivo Therapeutic Efficacy Evaluation in Various Mouse Models; paragraph 39: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4247,toxicity_endpoint,480,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Assessment of oligonucleotide toxicity (LD50) using the MTT assay; paragraph 13: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4248,toxicity_endpoint,481,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Cytotoxicity of mPEG-Azo-PEI; paragraph 50: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4249,toxicity_endpoint,482,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Synergistic Effect of Ferroptosis Induction via GPX4 Inhibition and PDT; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4250,toxicity_endpoint,483,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > siPAI-1 does not elicit overt toxicity in vivo.; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4251,toxicity_endpoint,484,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4252,toxicity_endpoint,485,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > The siLin28b Plus BMN673 Combination Inhibits the Deterioration of Vascular Permeability; paragraph 44: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4253,toxicity_endpoint,486,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 4. Discussion; paragraph 58: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4254,toxicity_endpoint,487,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4255,toxicity_endpoint,488,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4256,toxicity_endpoint,489,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Effects of CuONPs on cellular responses and signaling pathways in NCI–H292 cells; paragraph 29: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4257,toxicity_endpoint,490,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Cartilage Injury Repair in Immunocompromised Mice; paragraph 25: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4258,toxicity_endpoint,491,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > Silencing of EGFR attenuates the cytotoxic, pro-apoptotic and anti-invasive properties of Utt-B; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4259,toxicity_endpoint,492,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Treatment continuation; paragraph 33: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4260,toxicity_endpoint,493,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Cell culture; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4261,toxicity_endpoint,494,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4262,toxicity_endpoint,495,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > P. g-LPS inhibited 5-FU-induced cytotoxicity in OM-1 cells and HOC621 cells; paragraph 21: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4263,toxicity_endpoint,496,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4264,toxicity_endpoint,497,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Evaluating the cytotoxicity of transfection methods in AML; Figure 5 caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4265,toxicity_endpoint,498,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > CREB2 Mediates p53-Associated GADD45α Expression during Glutamate-Induced Oxidative Cytotoxicity; paragraph 41: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4266,toxicity_endpoint,499,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety; paragraph 35: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4267,toxicity_endpoint,500,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety evaluation through serum biochemistry; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4268,toxicity_endpoint,501,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4269,toxicity_endpoint,502,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4270,toxicity_endpoint,503,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Severe motor disability observed in Cypor-shRNA-treated animals; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4271,toxicity_endpoint,504,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Characterization of MnO2 Nanosheets for SUPER Delivery and DNAzyme Catalysis; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4272,toxicity_endpoint,505,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion > Reduction in ABCB10 Expression Does Not Cause Diaphragm Dysfunction; paragraph 40: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4273,toxicity_endpoint,506,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ALOX15B silencing promotes tumor cell proliferation and resistance to doxorubicin; paragraph 40: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4274,toxicity_endpoint,507,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > SMARCAL1 Depletion Leads to a hyper-ALT State and DNA Damage in G2 Phase; paragraph 38: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4275,toxicity_endpoint,508,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4276,toxicity_endpoint,509,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Cytotoxicity Assessment of Dendrimers; paragraph 43: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4277,toxicity_endpoint,510,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > In Vitro Photo‐Controlled Activation and Cytotoxicity of PURH; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4278,toxicity_endpoint,511,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PDL E inhibits viability of MDA-MB-231 DOX RT cells in 2D and 3D cultures; paragraph 36: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4279,toxicity_endpoint,512,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Patient eligibility; paragraph 16: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4280,toxicity_endpoint,513,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASO 8–3419 Enhances the Therapeutic Effect of Cisplatin in Xenografted HCT116 Tumors in Nude Mice; paragraph 26: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4281,toxicity_endpoint,514,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Subcutaneous administration allows for optimal distribution and is not toxic to mice; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4282,toxicity_endpoint,515,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Side effects and toxicity; paragraph 47: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4283,toxicity_endpoint,516,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4284,toxicity_endpoint,517,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Prenatal IA ASO administration enhances therapeutic efficacy in SMAΔ7 mice; paragraph 10: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4285,toxicity_endpoint,518,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety > AZD8701 monotherapy; paragraph 39: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4286,toxicity_endpoint,519,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.2. Revealing the Type of Interaction Between µ-ASO and Cytostatics Applied Together on KB-8-5 Cells (Additive/Synergistic Effects); paragraph 43: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4287,toxicity_endpoint,520,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety evaluation of Chol-HDO[PMO]; paragraph 27: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4288,toxicity_endpoint,521,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.1. Reagents and Materials; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4289,toxicity_endpoint,522,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > GMP grade exosomes for siRNA delivery showed no toxicity in preclinical studies; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4290,toxicity_endpoint,523,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Olpasiran; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4291,toxicity_endpoint,524,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4292,toxicity_endpoint,525,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4293,toxicity_endpoint,526,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASOs targeting human SARM1 rescue human iPSC-derived dopamine neurons from vacor toxicity; paragraph 17: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4294,toxicity_endpoint,527,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4295,toxicity_endpoint,528,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results and Discussion > 3.12. Safety Evaluation; paragraph 56: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4296,toxicity_endpoint,529,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at RESULTS > D-siRNA supports safe, potent and durable activity in the CNS; paragraph 24: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4297,toxicity_endpoint,530,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Muscle-optimal siRNA scaffold achieves systemic muscle effects and has a favorable safety profile; Figure 6. caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4298,toxicity_endpoint,531,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety profiles of KC13-M2G2 in SD rats and cynomolgus monkeys; paragraph 19: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4299,toxicity_endpoint,532,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > RNAi-induced cytotoxicity in aedine cell lines; paragraph 27: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4300,toxicity_endpoint,533,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.2. Cytotoxicity of CPP–PNA Conjugates in Mammalian Cells; paragraph 7: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4301,toxicity_endpoint,534,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Characterization and in vivo toxicity assay of engineered BEVs; paragraph 42: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4302,toxicity_endpoint,535,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.6. Targeted Delivery of MTA2 siRNA via AS1411 Liposomes Elicits Potent Anticancer Effects in Pancreatic Cancer Cells; paragraph 28: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4303,toxicity_endpoint,536,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4304,toxicity_endpoint,537,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PRM‐siRNA Suppressed Aβ‐Induced Neurotoxicity by Inhibiting ROS‐Mediated Oxidative Damage and Regulating Bcl‐2 Family in Rat Primary Neurons; paragraph 22: primary toxicity support for DNA damage response in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4305,toxicity_endpoint,538,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at OBSERVATION; Fig 1 caption: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4306,toxicity_endpoint,539,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Biocompatibility of Cleavable Dendrimers; paragraph 51: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4307,toxicity_endpoint,540,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > L2-siRNA does not induce hallmarks of toxicity; paragraph 54: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4308,toxicity_endpoint,541,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Genome-wide esiRNA screening identified SNX5 knockdown as being protective against αSyn-induced toxicity; paragraph 32: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4309,toxicity_endpoint,542,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4310,toxicity_endpoint,543,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Anti-Tumor Efficacy and Safety Evaluation in Vivo; paragraph 63: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4311,toxicity_endpoint,544,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.8. Acute Toxicity (LDH Release); paragraph 25: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4312,toxicity_endpoint,545,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Conclusion; paragraph 41: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4313,toxicity_endpoint,546,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.8. Toxicity Pathways Evaluation; paragraph 22: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4314,toxicity_endpoint,547,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS AND DISCUSSION > Assessment of Pdots in vitro labeling and cytotoxicity; paragraph 27: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4315,toxicity_endpoint,548,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Reduced 5’ end- and -2’- fluoro modification design; paragraph 37: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4316,toxicity_endpoint,549,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4317,toxicity_endpoint,550,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results; paragraph 22: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4318,toxicity_endpoint,551,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Specific Gene Silencing Studies; paragraph 21: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4319,toxicity_endpoint,552,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Lipidomic Profiling Identifies SMS2-Mediated Sphingomyelin Synthesis and Lipid Desaturation in Oxidative Stress-Driven Dry Eye Disease; paragraph 29: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4320,toxicity_endpoint,553,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 32: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4321,toxicity_endpoint,554,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Discussion; paragraph 40: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4322,toxicity_endpoint,555,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4323,toxicity_endpoint,556,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > NP containing PCSK9 siRNA and STING agonists enable safe and effective cancer immunotherapy; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4324,toxicity_endpoint,557,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4325,toxicity_endpoint,558,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4326,toxicity_endpoint,559,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4327,toxicity_endpoint,560,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.4. Evaluation of the Cytotoxic Effects of Ternary Polyplexes; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4328,toxicity_endpoint,561,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Targeting MALAT1 suppresses patient MM cell viability and CD38 expression; paragraph 35: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4329,toxicity_endpoint,562,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods and materials > Effects of NAG in siRNA-induced Gaucher mouse model; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4330,toxicity_endpoint,563,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Microbiome impacts on motor deficits and gene expression in the brains of Thy1-ASO mice; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4331,toxicity_endpoint,564,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4332,toxicity_endpoint,565,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at article body; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4333,toxicity_endpoint,566,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Inhalation of mscFv/siPD-L1@LNP drives TME reconfiguration in orthotopic lung tumors; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4334,toxicity_endpoint,567,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.4. Transfection with TG2-Specific siRNA Increases Cisplatin Cytotoxicity in Wild-Type MCF-7 Cells; paragraph 18: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4335,toxicity_endpoint,568,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Cell viability assay; paragraph 25: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4336,toxicity_endpoint,569,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Transient and Stable shRNA Transfections; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4337,toxicity_endpoint,570,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4338,toxicity_endpoint,571,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4339,toxicity_endpoint,572,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 48: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4340,toxicity_endpoint,573,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Cytotoxicity and degranulation assay; paragraph 39: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4341,toxicity_endpoint,574,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4342,toxicity_endpoint,575,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4343,toxicity_endpoint,576,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 47: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4344,toxicity_endpoint,577,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.6. Selective TRPC3 Inhibition Renders Synaptic Protection Against AβOs; paragraph 46: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4345,toxicity_endpoint,578,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > DG9-PMO facilitates enhanced cellular uptake and efficacious nuclear localization; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4346,toxicity_endpoint,579,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > CD8+ T cell cytotoxicity assay; paragraph 19: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4347,toxicity_endpoint,580,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > SPTBN1 silencing restores tumor-suppressive TGF-β signaling; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4348,toxicity_endpoint,581,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > In vitro Antitumor Effect of E-cLip-DTX / Si; paragraph 46: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4349,toxicity_endpoint,582,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > BPNPs Exposure Provokes Mitophagy via the PINK1/Parkin Signaling Pathway in Trophoblast Cells; paragraph 16: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4350,toxicity_endpoint,583,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and discussion > In vivo anti-tumor activity of DS-ARGN; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4351,toxicity_endpoint,584,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4352,toxicity_endpoint,585,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4353,toxicity_endpoint,586,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4354,toxicity_endpoint,587,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Three-month rat toxicology study; paragraph 38: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4355,toxicity_endpoint,588,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and discussion > Effect of Dox-loaded AS-T9/U4_MH on cell proliferation; paragraph 31: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4356,toxicity_endpoint,589,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety aspects of the lead candidate AON; paragraph 43: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4357,toxicity_endpoint,590,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Functional characterization of resistant UVB‐treated HDFs; FIGURE 5 caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4358,toxicity_endpoint,591,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4359,toxicity_endpoint,592,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Calcein AM-based cytotoxicity assay; paragraph 31: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4360,toxicity_endpoint,593,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Discussion; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4361,toxicity_endpoint,594,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 32: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4362,toxicity_endpoint,595,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Inhibition of BARD1 enhances therapeutic efficacy of DNA damage response agents; paragraph 30: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4363,toxicity_endpoint,596,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Nanoconjugate Dendrimer/Aptamer Formation and Characterization; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4364,toxicity_endpoint,597,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 4 Materials and methods > 4.3 Evaluation of inhibitory activity of modified ASOs in 22Rv1 prostate cancer cells; paragraph 27: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4365,toxicity_endpoint,598,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Pre-saturation with calcium reduces acute neurotoxicity; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4366,toxicity_endpoint,599,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > REST_SSO exerts antitumor effects in an NE cancer xenograft mouse model; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4367,toxicity_endpoint,600,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > End-points > Safety; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4368,toxicity_endpoint,601,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at DISCUSSION > Risk of adverse effects; paragraph 53: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4369,toxicity_endpoint,602,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > siRNA-LNPs displayed a low risk of CARPA and other toxicities; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4370,toxicity_endpoint,603,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4371,toxicity_endpoint,604,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS AND DISCUSSION; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4372,toxicity_endpoint,605,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4373,toxicity_endpoint,606,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4374,toxicity_endpoint,607,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.3. Intrinsic Toxicity and Transfection Efficiency of TRIFAPYs; paragraph 31: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4375,toxicity_endpoint,608,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Biocompatibility Test of Different Scaffolds; paragraph 34: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4376,toxicity_endpoint,609,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Animal experiments; paragraph 12: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4377,toxicity_endpoint,610,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4378,toxicity_endpoint,611,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 31: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4379,toxicity_endpoint,612,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4380,toxicity_endpoint,613,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Immunohistochemical Analysis; paragraph 42: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4381,toxicity_endpoint,614,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and Methods > Mice; paragraph 21: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4382,toxicity_endpoint,615,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 5. Conclusions; paragraph 51: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4383,toxicity_endpoint,616,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.3. Functional and Safety Assessments; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4384,toxicity_endpoint,617,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > RNP-tMNV nanotherapeutics; paragraph 12: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4385,toxicity_endpoint,618,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4386,toxicity_endpoint,619,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.5. Effects of siRNA Silencing of TG2 Expression on the Uptake of Cisplatin; paragraph 33: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4387,toxicity_endpoint,620,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > The p38 MAPK/H2AX/Mcl-1 axis plays a critical regulatory role in HHT-induced apoptosis; paragraph 22: primary toxicity support for DNA damage response in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4388,toxicity_endpoint,621,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at METHODS > Drug sensitivity assay; paragraph 13: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4389,toxicity_endpoint,622,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 9: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4390,toxicity_endpoint,623,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety; paragraph 27: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4391,toxicity_endpoint,624,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Doxorubicin in combination with OKI-005 retains effectiveness with loss of wild-type p53; paragraph 29: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4392,toxicity_endpoint,625,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 62: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4393,toxicity_endpoint,626,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Treatment exposure and safety; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4394,toxicity_endpoint,627,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS AND DISCUSSION > Evaluation of the efficacy of gene silencing with in vitro RT-PCR; paragraph 45: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4395,toxicity_endpoint,628,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Influence of Nanoparticles on Tumor Growth and Survival Time in Orthotopic Glioblastoma Mice and Its Evaluation of Immunogenicity and Toxicity; paragraph 53: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4396,toxicity_endpoint,629,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Toxicity of cRGD-PEG-siRNA to Renal Tubular Epithelial Cells; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4397,toxicity_endpoint,630,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.1. Survey; paragraph 21: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4398,toxicity_endpoint,631,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and discussion > Inflammatory inhibition effect of the hybrid nanocomposite; paragraph 40: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4399,toxicity_endpoint,632,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > siRNA-mediated knockdown of inflammatory factors in peripheral blood -derived CAR-NK cells reduces bystander myeloid cell activation; paragraph 39: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4400,toxicity_endpoint,633,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4401,toxicity_endpoint,634,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4402,toxicity_endpoint,635,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Cytotoxicity Assay; paragraph 65: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4403,toxicity_endpoint,636,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results and Discussion > 3.6. Evaluation of the In Vitro Cytotoxicity of PTX@PHBHHx-ARP/siRNAGEM; paragraph 36: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4404,toxicity_endpoint,637,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4405,toxicity_endpoint,638,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4406,toxicity_endpoint,639,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Optimized BROTHERS architectures mitigate hepatotoxicity without affecting antisense activity; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4407,toxicity_endpoint,640,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 4. Materials and Methods > 4.8. Cytotoxicity Assay; paragraph 37: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4408,toxicity_endpoint,641,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4409,toxicity_endpoint,642,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > SH-BC-893 increases ASO delivery and activity in vitro; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4410,toxicity_endpoint,643,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 24: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4411,toxicity_endpoint,644,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Design of locked nucleic acid (LNA) ASO gapmers targeting Atp1a2; Fig 1 caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4412,toxicity_endpoint,645,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4413,toxicity_endpoint,646,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > CPP-PMO antimiRs improve histopathology signs and muscle function in HSALR; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4414,toxicity_endpoint,647,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > Treatment with G2C4, but not G4C2, targeting ASOs reverses molecular hallmarks of TDP-43 loss of function in C9orf72 patient iPSNs; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4415,toxicity_endpoint,648,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Effect of Notch3 ASOs on Notch3 Expression in Cells of the Osteoblast Lineage; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4416,toxicity_endpoint,649,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > ASO treatment of mice; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4417,toxicity_endpoint,650,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Synergistic antitumor effects in vivo; paragraph 29: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4418,toxicity_endpoint,651,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4419,toxicity_endpoint,652,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4420,toxicity_endpoint,653,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at 2. Results > 2.2. Reduction in Macrophage Pro-Inflammation with mgmt Interferences after Either a Single LPS or Two Sequential LPS Stimulations: The Beneficial Effect in Hyper-Inflammatory Sepsis, but Not LPS Tolerance; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4421,toxicity_endpoint,654,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Safety; paragraph 27: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4422,toxicity_endpoint,655,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4423,toxicity_endpoint,656,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at DISCUSSION; paragraph 60: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4424,toxicity_endpoint,657,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4425,toxicity_endpoint,658,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > DG9-PMO treatment rescues the SMA phenotype without apparent toxicity.; paragraph 19: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4426,toxicity_endpoint,659,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.6. CCK-BR Targeted NPs Exhibit Broad Safety Profile and Lack off Target Toxicity; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4427,toxicity_endpoint,660,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > MsPA backbone improves potency, whereas gap2 OMe reduces toxicity in cytotoxic PS ASOs; FIG. 1. caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4428,toxicity_endpoint,661,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Initial tiling screen identified a parental ASO targeting the 3′ UTR of MAPT with high cross-species reactivity; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4429,toxicity_endpoint,662,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Single-dose tolerability study of lead ASO candidates in cynomolgus monkeys; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4430,toxicity_endpoint,663,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Anti-HIF-1-α ASO-ND conjugates are active in vitro; paragraph 16: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4431,toxicity_endpoint,664,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > LNP containing DSPS can reach the cytoplasm of cells without detectable cytotoxicity; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4432,toxicity_endpoint,665,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Cell Toxicity of Dendron–PNAs; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4433,toxicity_endpoint,666,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety; paragraph 28: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4434,toxicity_endpoint,667,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Reduction of NAT10 and DDX21 increases the cytotoxicity induced by toxic PS-ASOs; paragraph 66: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4435,toxicity_endpoint,668,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PS reduction optimizes ASO5 safety and activity in mice; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4436,toxicity_endpoint,669,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Enhancement of the 125I-Induced Anti-Cancer Effects by EPI via the JAK/STAT1 Pathway; paragraph 30: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4437,toxicity_endpoint,670,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and Methods > The Cytotoxicity Studies of iRGD Functionalized Lipopolysaccharide-Amine Nanopolymersomes to Mesenchymal Stem Cells; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4438,toxicity_endpoint,671,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and discussion > In vivo anticancer activity and safety evaluation; paragraph 49: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4439,toxicity_endpoint,672,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS AND DISCUSSION > Hairpin-like Design Increases Serum Nuclease Resistance and Decreases SNA Cytotoxicity.; paragraph 12: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4440,toxicity_endpoint,673,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Abstract; paragraph 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4441,toxicity_endpoint,674,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Discussion; paragraph 41: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4442,toxicity_endpoint,675,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4443,toxicity_endpoint,676,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASO1-cEt/DNA inhibits HCC cell growth; paragraph 29: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4444,toxicity_endpoint,677,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 4. Discussion; paragraph 36: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4445,toxicity_endpoint,678,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4446,toxicity_endpoint,679,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > In Vivo Effects of NVP-13 on Target Regulation and Intracellular Pathways: NVP-13 is a Safe and Effective Compound in Cynomolgus Monkeys; paragraph 8: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4447,toxicity_endpoint,680,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4448,toxicity_endpoint,681,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 28: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4449,toxicity_endpoint,682,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Impact of GNA isonucleotides on GalNAc-siRNA activity in mice; paragraph 51: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4450,toxicity_endpoint,683,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4451,toxicity_endpoint,684,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 5. Conclusions; paragraph 30: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4452,toxicity_endpoint,685,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4453,toxicity_endpoint,686,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety of Combined Therapy with CpG and the mRNA Vaccine; paragraph 28: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4454,toxicity_endpoint,687,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.4. Method for Measuring Cytotoxic Effect of Compounds; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4455,toxicity_endpoint,688,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Increased hepatic SAB expression and P-JNK activation in diet-induced NAFLD; paragraph 12: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4456,toxicity_endpoint,689,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4457,toxicity_endpoint,690,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 2: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4458,toxicity_endpoint,691,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Identification of potential regulators of the selective alt-NHEJ inhibition of mibefradil; Figure 6 caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4459,toxicity_endpoint,692,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4460,toxicity_endpoint,693,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at RESULTS > Effect of site-specific incorporation of R- and S-5′-methyl DNA on duplex thermal stability, ASO activity and toxicity in cells; Figure 3. caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4461,toxicity_endpoint,694,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PMO‐M improves muscle pathologies without detectable toxicity in mdx mice; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4462,toxicity_endpoint,695,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.1. Discovery Process; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4463,toxicity_endpoint,696,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Toxicity status of chimeric LNA/2′OMe ASOs in vivo; paragraph 34: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4464,toxicity_endpoint,697,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4465,toxicity_endpoint,698,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Discussion; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4466,toxicity_endpoint,699,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4467,toxicity_endpoint,700,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > MYC ASO Treatment Is Not Associated with Morbidity, Mortality, or Toxicity; paragraph 12: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4468,toxicity_endpoint,701,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Hybridization Properties of µ-ODNs Targeting miR-21.; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4469,toxicity_endpoint,702,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Evaluation of in vitro cytotoxicity of the 2′-F modified AOs; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4470,toxicity_endpoint,703,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > A single MOP linkage at position 2 in the DNA gap reduces toxicity for multiple ASOs; paragraph 46: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4471,toxicity_endpoint,704,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results and Discussion > 2.4. CL-4RNV616 Aptamer Initiated Strong Cytotoxicity in EGFR Positive Cancer Cells; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4472,toxicity_endpoint,705,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Di-siRNA are safe and well-tolerated in mice; paragraph 21: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4473,toxicity_endpoint,706,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Phase I study results > Safety and tolerability; paragraph 45: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4474,toxicity_endpoint,707,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4475,toxicity_endpoint,708,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > BMSP-PMO-GF Does Not Evoke Any Overt Toxicity in Adult mdx Mice; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4476,toxicity_endpoint,709,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > RNase H1 is required for the formation of the nucleolar P54nrb/ASO complex; paragraph 29: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4477,toxicity_endpoint,710,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4478,toxicity_endpoint,711,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and discussion > Cytotoxicity studies; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4479,toxicity_endpoint,712,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Carrier-free Splice Switching with Spermine-Grafted SSOs in Monolayer Culture; paragraph 9: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4480,toxicity_endpoint,713,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > PPMO Therapy Has Low Toxicity at MIC50 Concentrations and Reduces Bcc in a Mouse Model of Pneumonia; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4481,toxicity_endpoint,714,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PMO-GF Maintains Functional Rescue without Detectable Toxicity in mdx Mice; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4482,toxicity_endpoint,715,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4483,toxicity_endpoint,716,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 2: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4484,toxicity_endpoint,717,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4485,toxicity_endpoint,718,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results and Discussion > 3.1. Cytotoxicity; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4486,toxicity_endpoint,719,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and Methods > Phase 1 dose-escalation clinical studies; paragraph 10: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4487,toxicity_endpoint,720,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Local Delivery of Z-Mediated PMO In Vivo; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4488,toxicity_endpoint,721,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4489,toxicity_endpoint,722,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > CAG ONs can be delivered to patient fibroblasts by peptide and gymnotic delivery; paragraph 36: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4490,toxicity_endpoint,723,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.10. Cytotoxicity study; paragraph 19: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4491,toxicity_endpoint,724,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4492,toxicity_endpoint,725,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4493,toxicity_endpoint,726,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Long-term use of fructose does not elicit any overt toxicity in mdx mice; paragraph 12: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4494,toxicity_endpoint,727,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > P27 is upregulated in mouse tissues after LNA-i-miR-221 treatment; paragraph 8: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4495,toxicity_endpoint,728,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4496,toxicity_endpoint,729,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Mstn siRNA cholesterol conjugate shows dose-dependent and sustained knockdown of Mstn mRNA in muscle and in circulating protein levels; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4497,toxicity_endpoint,730,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Toxicity assessment of systemic administration of miR-205-LNA-inhibitor; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4498,toxicity_endpoint,731,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4499,toxicity_endpoint,732,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > MOs rescue apoptosis-mediated death in fALS induced pluripotent stem cell-derived motor neurons; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4500,toxicity_endpoint,733,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Cell culture and PCR; paragraph 23: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4501,toxicity_endpoint,734,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Systemic administration of GS-PPMO does not elicit overt changes in histopathology and blood chemistry; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4502,toxicity_endpoint,735,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4503,toxicity_endpoint,736,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4504,toxicity_endpoint,737,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4505,toxicity_endpoint,738,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Toxicity of the different AMO designs; paragraph 35: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4506,toxicity_endpoint,739,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4507,toxicity_endpoint,740,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Cytotoxicity of LNA ASO; paragraph 45: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4508,toxicity_endpoint,741,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at MATERIALS AND METHODS > Mouse studies; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4509,toxicity_endpoint,742,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4510,toxicity_endpoint,743,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4511,toxicity_endpoint,744,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 5: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4512,toxicity_endpoint,745,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4513,toxicity_endpoint,746,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4514,toxicity_endpoint,747,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4515,toxicity_endpoint,748,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4516,toxicity_endpoint,749,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4517,toxicity_endpoint,750,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4518,toxicity_endpoint,751,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4519,toxicity_endpoint,752,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 5: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4520,toxicity_endpoint,753,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4521,toxicity_endpoint,754,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4522,toxicity_endpoint,755,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4523,toxicity_endpoint,756,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4524,toxicity_endpoint,757,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4525,toxicity_endpoint,758,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4526,toxicity_endpoint,759,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4527,toxicity_endpoint,760,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4528,toxicity_endpoint,761,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4529,toxicity_endpoint,762,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4530,toxicity_endpoint,763,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4531,toxicity_endpoint,764,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4532,toxicity_endpoint,765,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4533,toxicity_endpoint,766,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4534,toxicity_endpoint,767,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4535,toxicity_endpoint,768,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4536,toxicity_endpoint,769,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4537,toxicity_endpoint,770,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4538,toxicity_endpoint,771,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4539,toxicity_endpoint,772,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4540,toxicity_endpoint,773,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4541,toxicity_endpoint,774,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4542,toxicity_endpoint,775,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4543,toxicity_endpoint,776,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4544,toxicity_endpoint,777,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4545,toxicity_endpoint,778,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4546,toxicity_endpoint,779,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4547,toxicity_endpoint,780,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4548,toxicity_endpoint,781,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4549,toxicity_endpoint,782,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4550,toxicity_endpoint,783,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4551,toxicity_endpoint,784,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4552,toxicity_endpoint,785,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4553,toxicity_endpoint,786,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4554,toxicity_endpoint,787,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4555,toxicity_endpoint,788,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4556,toxicity_endpoint,789,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4557,toxicity_endpoint,790,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4558,toxicity_endpoint,791,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4559,toxicity_endpoint,792,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4560,toxicity_endpoint,793,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4561,toxicity_endpoint,794,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4562,toxicity_endpoint,795,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4563,toxicity_endpoint,796,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4564,toxicity_endpoint,797,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4565,toxicity_endpoint,798,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4566,toxicity_endpoint,799,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4567,toxicity_endpoint,800,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4568,toxicity_endpoint,801,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4569,toxicity_endpoint,802,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4570,toxicity_endpoint,803,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4571,toxicity_endpoint,804,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4572,toxicity_endpoint,805,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4573,toxicity_endpoint,806,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4574,toxicity_endpoint,807,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4575,toxicity_endpoint,808,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4576,toxicity_endpoint,809,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4577,toxicity_endpoint,810,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4578,toxicity_endpoint,811,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4579,toxicity_endpoint,812,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4580,toxicity_endpoint,813,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4581,toxicity_endpoint,814,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4582,toxicity_endpoint,815,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 8: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4583,toxicity_endpoint,816,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4584,toxicity_endpoint,817,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4585,toxicity_endpoint,818,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4586,toxicity_endpoint,819,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4587,toxicity_endpoint,820,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4588,toxicity_endpoint,821,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4589,toxicity_endpoint,822,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4590,toxicity_endpoint,823,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4591,toxicity_endpoint,824,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 2: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4592,toxicity_endpoint,825,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4593,toxicity_endpoint,826,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 8: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4594,toxicity_endpoint,827,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 5: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4595,toxicity_endpoint,828,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4596,toxicity_endpoint,829,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4597,toxicity_endpoint,830,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4598,toxicity_endpoint,831,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4599,toxicity_endpoint,832,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4600,toxicity_endpoint,833,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4601,toxicity_endpoint,834,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4602,toxicity_endpoint,835,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4603,toxicity_endpoint,836,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4604,toxicity_endpoint,837,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4605,toxicity_endpoint,838,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4606,toxicity_endpoint,839,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4607,toxicity_endpoint,840,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4608,toxicity_endpoint,841,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4609,toxicity_endpoint,842,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4610,toxicity_endpoint,843,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4611,toxicity_endpoint,844,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4612,toxicity_endpoint,845,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4613,toxicity_endpoint,846,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4614,toxicity_endpoint,847,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4615,toxicity_endpoint,848,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4616,toxicity_endpoint,849,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4617,toxicity_endpoint,850,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4618,toxicity_endpoint,851,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4619,toxicity_endpoint,852,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4620,toxicity_endpoint,853,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4621,toxicity_endpoint,854,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4622,toxicity_endpoint,855,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4623,toxicity_endpoint,856,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4624,toxicity_endpoint,857,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4625,toxicity_endpoint,858,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4626,toxicity_endpoint,859,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4627,toxicity_endpoint,860,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4628,toxicity_endpoint,861,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4629,toxicity_endpoint,862,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4630,toxicity_endpoint,863,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4631,toxicity_endpoint,864,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4632,toxicity_endpoint,865,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4633,toxicity_endpoint,866,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4634,toxicity_endpoint,867,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4635,toxicity_endpoint,868,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4636,toxicity_endpoint,869,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4637,toxicity_endpoint,870,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4638,toxicity_endpoint,871,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4639,toxicity_endpoint,872,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4640,toxicity_endpoint,873,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4641,toxicity_endpoint,874,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4642,toxicity_endpoint,875,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4643,toxicity_endpoint,876,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4644,toxicity_endpoint,877,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4645,toxicity_endpoint,878,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4646,toxicity_endpoint,879,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4647,toxicity_endpoint,880,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4648,toxicity_endpoint,881,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4649,toxicity_endpoint,882,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 6: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4650,toxicity_endpoint,883,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4651,toxicity_endpoint,884,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4652,toxicity_endpoint,885,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4653,toxicity_endpoint,886,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4654,toxicity_endpoint,887,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4655,toxicity_endpoint,888,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4656,toxicity_endpoint,889,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4657,toxicity_endpoint,890,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4658,toxicity_endpoint,891,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4659,toxicity_endpoint,892,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4660,toxicity_endpoint,893,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4661,toxicity_endpoint,894,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4662,toxicity_endpoint,895,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4663,toxicity_endpoint,896,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 12: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4664,toxicity_endpoint,897,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4665,toxicity_endpoint,898,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 6: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4666,toxicity_endpoint,899,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4667,toxicity_endpoint,900,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4668,toxicity_endpoint,901,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4669,toxicity_endpoint,902,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4670,toxicity_endpoint,903,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4671,toxicity_endpoint,904,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4672,toxicity_endpoint,905,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4673,toxicity_endpoint,906,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4674,toxicity_endpoint,907,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4675,toxicity_endpoint,908,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4676,toxicity_endpoint,909,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4677,toxicity_endpoint,910,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4678,toxicity_endpoint,911,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4679,toxicity_endpoint,912,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4680,toxicity_endpoint,913,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4681,toxicity_endpoint,914,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4682,toxicity_endpoint,915,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4683,toxicity_endpoint,916,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4684,toxicity_endpoint,917,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4685,toxicity_endpoint,918,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4686,toxicity_endpoint,919,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4687,toxicity_endpoint,920,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4688,toxicity_endpoint,921,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4689,toxicity_endpoint,922,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4690,toxicity_endpoint,923,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4691,toxicity_endpoint,924,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4692,toxicity_endpoint,925,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4693,toxicity_endpoint,926,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4694,toxicity_endpoint,927,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4695,toxicity_endpoint,928,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4696,toxicity_endpoint,929,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4697,toxicity_endpoint,930,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 2: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4698,toxicity_endpoint,931,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 3: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4699,toxicity_endpoint,932,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4700,toxicity_endpoint,933,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4701,toxicity_endpoint,934,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4702,toxicity_endpoint,935,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4703,toxicity_endpoint,936,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4704,toxicity_endpoint,937,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4705,toxicity_endpoint,938,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4706,toxicity_endpoint,939,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4707,toxicity_endpoint,940,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4708,toxicity_endpoint,941,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4709,toxicity_endpoint,942,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4710,toxicity_endpoint,943,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4711,toxicity_endpoint,944,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4712,toxicity_endpoint,945,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4713,toxicity_endpoint,946,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4714,toxicity_endpoint,947,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4715,toxicity_endpoint,948,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4716,toxicity_endpoint,949,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4717,toxicity_endpoint,950,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4718,toxicity_endpoint,951,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4719,toxicity_endpoint,952,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 5: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4720,toxicity_endpoint,953,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4721,toxicity_endpoint,954,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4722,toxicity_endpoint,955,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4723,toxicity_endpoint,956,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Development of ATN1 allele-specific ASOs; paragraph 8: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4724,toxicity_endpoint,957,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Study Population; paragraph 30: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4725,toxicity_endpoint,958,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Cell viability assay; paragraph 31: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4726,toxicity_endpoint,959,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > DUX4 AOC-mediated prevention of the FSHD phenotype in a mouse model; Figure 4. caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4727,toxicity_endpoint,960,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Discussion > 3.4. Results of In Vitro Testing of Target GalNAc-Oligonucleotide Conjugates; paragraph 60: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4728,toxicity_endpoint,961,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4729,toxicity_endpoint,962,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results; paragraph 21: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4730,toxicity_endpoint,963,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > In silico off-targets analysis; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4731,toxicity_endpoint,964,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > In silico off-targets analysis; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4732,toxicity_endpoint,965,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Administration of ASOs and HDOs; paragraph 11: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4733,toxicity_endpoint,966,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Evaluation of the Toxicity and Safety of IVSA‐siRNA Targeting MSTN; paragraph 28: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4734,toxicity_endpoint,967,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > Sequence specific screening identifies highly potent siRNAs that enhance FXR1 silencing, inhibit cell growth, and promote apoptosis; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4735,toxicity_endpoint,968,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4736,toxicity_endpoint,969,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > IC50, time course, and viability analysis; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4737,toxicity_endpoint,970,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > CLENs (siRNA) exhibit excellent biological safety; paragraph 37: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4738,toxicity_endpoint,971,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Maternal administration of siSaa2 reduces placental SAA2 expression following sub-chronic maternal inflammation; FIGURE 2 caption: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4739,toxicity_endpoint,972,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at 3. Results > 3.8. Histological Suppression of CNV and Inflammation, and Systemic Safety of VEGFA siRNA-FAM-Loaded Exosomes; paragraph 37: primary toxicity support for toxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4740,toxicity_endpoint,973,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and discussion; paragraph 38: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4741,toxicity_endpoint,974,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > S9-SNA ameliorated the phenotype of SBMA mice; paragraph 12: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4742,toxicity_endpoint,975,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Reduction in circPROSC Inhibits Premature Fusion of the Coronal Suture of the Skull in Mice with Craniosynostosis; paragraph 19: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4743,toxicity_endpoint,976,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Material & methods > Materials; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4744,toxicity_endpoint,977,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4745,toxicity_endpoint,978,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Patient characteristics and pathological assessment; paragraph 27: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4746,toxicity_endpoint,979,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4747,toxicity_endpoint,980,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4748,toxicity_endpoint,981,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4749,toxicity_endpoint,982,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RNA-Targeted Therapeutics for Lipid-Metabolic Disorders: Bench Evidence; paragraph 33: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4750,toxicity_endpoint,983,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Mechanisms of therapeutic resistance are revealed by functional enrichment; paragraph 21: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4751,toxicity_endpoint,984,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > DNA‐PKcs Inhibition Enhances Irradiation‐Induced DSBs and Modulates Associated DDR; FIGURE 4 caption: primary toxicity support for DNA damage response in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4752,toxicity_endpoint,985,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods; paragraph 10: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4753,toxicity_endpoint,986,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Methodology > 2.12. Quantitative Real-Time PCR (qRT-PCR); paragraph 24: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4754,toxicity_endpoint,987,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > KIF14 contributes to MYCBP2-dependent AML cell phenotypes; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4755,toxicity_endpoint,988,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4756,toxicity_endpoint,989,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4757,toxicity_endpoint,990,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > FH535-induced inhibition of Wnt/β-catenin exerts immunomodulatory effects on the CRC TME; Figure 6 caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4758,toxicity_endpoint,991,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PDP achieves efficient intracellular siRNA delivery for functional HIF-1α silencing under hypoxia; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4759,toxicity_endpoint,992,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Experimental design for epistasis and pharmacologic rescue; paragraph 32: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4760,toxicity_endpoint,993,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PRMT5 inhibition increases the sensitivity of TMZ in GSCs; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4761,toxicity_endpoint,994,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > TIMAP knockdown alters morphology, cell adhesion and migration of A549 cells; paragraph 30: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4762,toxicity_endpoint,995,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Rab12 knockdown enhances basal and depolarization-induced mitophagy; paragraph 8: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4763,toxicity_endpoint,996,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Cytotoxicity; paragraph 39: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4764,toxicity_endpoint,997,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > In Vivo Safety and Toxicity Profile; paragraph 53: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4765,toxicity_endpoint,998,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > AdV-mediated TIPE2 knockdown ameliorates DSS-induced colitis; paragraph 10: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4766,toxicity_endpoint,999,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > In Vivo Therapeutic Efficacy for OLK; paragraph 18: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4767,toxicity_endpoint,1000,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Silencing SLC22A5 and GSTM1 Promotes the Proliferation and Migration of Breast Cancer Cells; paragraph 35: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4768,toxicity_endpoint,1001,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > The ANGPTL3-MSR1 Axis Drives Macrophage Activation via Interferon Signaling; paragraph 23: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4769,toxicity_endpoint,1002,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Targeted mitochondria enhance CA-induced cell apoptosis by regulating mitophagy via PINK1/Parkin pathway; paragraph 37: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4770,toxicity_endpoint,1003,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Animals; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4771,toxicity_endpoint,1004,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ERO1 is a key endoplasmic reticulum target that mediates STING-activated ADP-ribosylation; paragraph 49: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4772,toxicity_endpoint,1005,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Cell viability; paragraph 16: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4773,toxicity_endpoint,1006,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4774,toxicity_endpoint,1007,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4775,toxicity_endpoint,1008,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.2. Targeting CSA Reduces Tumorigenicity and Proliferative Capacity in Melanoma; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4776,toxicity_endpoint,1009,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > HPV16 E7/APC2 axis promotes the malignancy and stemness of cervical cancer by positively regulating SPIN4 expression in vitro and in vivo; paragraph 31: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4777,toxicity_endpoint,1010,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Design of amiRNAs and subcloning in viral vectors; paragraph 24: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4778,toxicity_endpoint,1011,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4779,toxicity_endpoint,1012,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4780,toxicity_endpoint,1013,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > VDAC1 and VDAC2 regulate proliferation, apoptosis, ferroptosis, and migration in HCC cells; Figure 7 caption: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4781,toxicity_endpoint,1014,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4782,toxicity_endpoint,1015,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Treatments and siRNA; paragraph 50: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4783,toxicity_endpoint,1016,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Engineered VNP Strain Exerts Enhanced Anti‐Melanoma Activity by Targeting GR in Neutrophils; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4784,toxicity_endpoint,1017,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > SMB nanoparticles target tumor cells and specifically accumulate in HCC tissues in vivo; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4785,toxicity_endpoint,1018,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > High expression of TMX4 in human melanoma tissues; paragraph 44: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4786,toxicity_endpoint,1019,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Chemicals and Reagents; paragraph 11: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4787,toxicity_endpoint,1020,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4788,toxicity_endpoint,1021,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > SSE Vaccine Exhibits Efficient Antigen Internalization and APC Activation; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4789,toxicity_endpoint,1022,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Effects of K18 and K8 on GCDCA‐induced hepatocyte apoptosis; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4790,toxicity_endpoint,1023,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > TFF3 Expression Is Induced in an Experimental Mouse Model of HB and Contributes to Tumour Growth; paragraph 28: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4791,toxicity_endpoint,1024,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > FATP2 silencing by siRNA impaired ZIKV production in SH-SY5Y; paragraph 36: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4792,toxicity_endpoint,1025,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4793,toxicity_endpoint,1026,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Irradiation exposure; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4794,toxicity_endpoint,1027,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 4. Materials and Methods > 4.3. In Vivo Xenograft Modeling; paragraph 54: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4795,toxicity_endpoint,1028,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Impact of Allele-Selective Silencing Of VWF In Vivo; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4796,toxicity_endpoint,1029,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Cytotoxicity of TRF and DUSP29 siRNA treatments in myoblast cells; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4797,toxicity_endpoint,1030,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > SAM68 silencing and cell viability assay; paragraph 25: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4798,toxicity_endpoint,1031,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Biological Methods > Cell Culture Treatments and Measurements; paragraph 173: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4799,toxicity_endpoint,1032,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASO targeting mouse Hnrnph2 in a non-allele-specific manner knocks down Hnrnph2 and upregulates Hnrnph1.; paragraph 7: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4800,toxicity_endpoint,1033,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results: > BIIB078 induces immune-related protein abundance changes.; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4801,toxicity_endpoint,1034,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 17: primary toxicity support for thrombocytopenia in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4802,toxicity_endpoint,1035,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods:; paragraph 2: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4803,toxicity_endpoint,1036,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Rab5‐ASOs reversed endosomal Rab hyperactivation and upregulation of RABs 7 and 11 GEFs in Dp16 brains; paragraph 40: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4804,toxicity_endpoint,1037,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Direct TRA2β protein knockdown does not phenocopy ASO-1570 effects; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4805,toxicity_endpoint,1038,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety (primary endpoint); paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4806,toxicity_endpoint,1039,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Alkyl phosphonate at positions 6–7 enhances the therapeutic profile and reduces hepatotoxicity of Ttr and Marc1 siRNAs; paragraph 65: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4807,toxicity_endpoint,1040,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Strand specificity of IgG1-DS5 recognition; paragraph 23: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4808,toxicity_endpoint,1041,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > NUP85 aggravates PAOA-induced hepatocyte lipid deposition, oxidative stress, and inflammatory response; paragraph 51: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4809,toxicity_endpoint,1042,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Chronic dual PMO therapy of D2-mdx improves dystrophin restoration and muscle health; paragraph 17: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4810,toxicity_endpoint,1043,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results:; paragraph 3: primary toxicity support for thrombocytopenia in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4811,toxicity_endpoint,1044,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Effects of apoCIII ASO treatment on monocyte phenotypes and atherosclerosis in Ldlr−/−ApoCIIItg mice; paragraph 38: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4812,toxicity_endpoint,1045,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Oligonucleotide Synthesis and Physical Properties > Splice‐Switching Activity Assay; paragraph 24: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4813,toxicity_endpoint,1046,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Evaluation of Cellular Cytotoxicity; paragraph 32: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4814,toxicity_endpoint,1047,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and discussion > Live cell gene silencing of Bcl2 using H2O2 inducible ABcl2@BO; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4815,toxicity_endpoint,1048,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Optimization of LNP2 formulation to enhance targeting of myeloid cells and B cells; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4816,toxicity_endpoint,1049,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > High Levels of TIGAR Correlate with the Recruitment of Stromal Endothelial Progenitors and Angiogenesis in Primary Colorectal Carcinoma Tissues; paragraph 19: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4817,toxicity_endpoint,1050,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety assessment; paragraph 23: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4818,toxicity_endpoint,1051,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Discussion; paragraph 19: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4819,toxicity_endpoint,1052,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4820,toxicity_endpoint,1053,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > TERT-selective and structure-dependent cytotoxicity of 6tdGO; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4821,toxicity_endpoint,1054,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > Lip@si-YTHDF2 significantly suppresses HCC stem cell proliferation, migration, invasion, and stemness by inhibiting MYC; paragraph 109: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4822,toxicity_endpoint,1055,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > Design, Characterization, and Biocompatibility of Lipo@si‐CD248; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4823,toxicity_endpoint,1056,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > CpG Formulation Results in Distinct Patterns of CpG Delivery to dLN APCs; paragraph 21: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4824,toxicity_endpoint,1057,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Lead MECP2-targeting siRNAs tune MECP2 levels in wildtype mice for up to four months; paragraph 16: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4825,toxicity_endpoint,1058,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PUREG4-LA12-anti-GLS1-siRNA promoted autophagy; paragraph 44: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4826,toxicity_endpoint,1059,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Drug screens; paragraph 51: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4827,toxicity_endpoint,1060,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Single injection of non-isoform selective 1764_S1 but not E1 selective 112_S1 induces mixed behavioral effects in Tg1 mice; paragraph 36: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4828,toxicity_endpoint,1061,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 10: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4829,toxicity_endpoint,1062,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4830,toxicity_endpoint,1063,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Knockdown of SMTN enhances chemosensitivity in vitro; paragraph 27: primary toxicity support for DNA damage response in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4831,toxicity_endpoint,1064,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.8. Histopathological Observation of Tissues; paragraph 15: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4832,toxicity_endpoint,1065,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4833,toxicity_endpoint,1066,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4834,toxicity_endpoint,1067,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4835,toxicity_endpoint,1068,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4836,toxicity_endpoint,1069,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Exploration of the therapeutic potential of ASO drugs targeting LncPEDS1-AS; paragraph 31: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4837,toxicity_endpoint,1070,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.5. Oligomer Scaffold Enhances Antigen Retention and Supports Vaccine-Induced Immune Cell Recruitment at the Injection Site; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4838,toxicity_endpoint,1071,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Loss of TERRA contributes to telomere attrition and senescence in LOPE trophoblast organoids; paragraph 29: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4839,toxicity_endpoint,1072,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Safety profile and adverse events; paragraph 22: primary toxicity support for thrombocytopenia in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4840,toxicity_endpoint,1073,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4841,toxicity_endpoint,1074,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4842,toxicity_endpoint,1075,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4843,toxicity_endpoint,1076,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4844,toxicity_endpoint,1077,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Cell viability detection; paragraph 13: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4845,toxicity_endpoint,1078,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4846,toxicity_endpoint,1079,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > CCK8 analysis; paragraph 13: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4847,toxicity_endpoint,1080,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.1. An Increased Expression of CLDN1 in GIST T-1 Cells Contributes to IM’s Resistance; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4848,toxicity_endpoint,1081,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Treatment switching; paragraph 27: primary toxicity support for thrombocytopenia in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4849,toxicity_endpoint,1082,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Differential Diagnosis, Investigations, and Treatment > Conclusion and Results (Outcome and Follow‐Up); paragraph 15: primary toxicity support for renal safety in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4850,toxicity_endpoint,1083,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Lactate dehydrogenase cytotoxicity assay; paragraph 31: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4851,toxicity_endpoint,1084,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Targeting the chr1:241498239 T/C variant with ASOs restores GFP expression; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4852,toxicity_endpoint,1085,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety and tolerability in NHPs (Study 2); paragraph 72: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4853,toxicity_endpoint,1086,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4854,toxicity_endpoint,1087,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Uptake and Conditional Gene Silencing in 3D Spheroids; paragraph 19: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4855,toxicity_endpoint,1088,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4856,toxicity_endpoint,1089,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4857,toxicity_endpoint,1090,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.4. Serum and Liver Analysis; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4858,toxicity_endpoint,1091,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4859,toxicity_endpoint,1092,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results; paragraph 36: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4860,toxicity_endpoint,1093,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4861,toxicity_endpoint,1094,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4862,toxicity_endpoint,1095,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > CCK8 assay; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4863,toxicity_endpoint,1096,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > LINC01235 KO/KD decreases proliferation of breast tumor luminal progenitor-like cells; paragraph 31: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4864,toxicity_endpoint,1097,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Combining KRAS G12D ASO with immRNA in RBCEVs elicits a potent response against KRAS-driven tumors; paragraph 19: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4865,toxicity_endpoint,1098,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4866,toxicity_endpoint,1099,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results and Discussion > 2.1. PnkRNA-Loaded Liposomal Eye Drops Inhibit Retinal Edema in Retinal-Vein Occlusion Model Mice > 2.1.3. Retinal Edema Therapeutic Evaluation of a Retinal-Vein Occlusion Mouse Model Following PnkRNA-Loaded Liposome Eye-Drop Administration; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4867,toxicity_endpoint,1100,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4868,toxicity_endpoint,1101,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 35: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4869,toxicity_endpoint,1102,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > STAU2‐ASO Inhibits PDAC Cell Progression, Invasion, and Migration by Regulating the EMT Pathway In Vitro; Figure 7 caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4870,toxicity_endpoint,1103,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4871,toxicity_endpoint,1104,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > In vitro studies > EC assays; paragraph 49: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4872,toxicity_endpoint,1105,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > In vivo biodistribution of FNLM‐p16‐siRNA in post‐MI murine models; paragraph 50: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4873,toxicity_endpoint,1106,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.15. CCK8 Methods; paragraph 23: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4874,toxicity_endpoint,1107,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Human cells repair DSBs using RNA as a template to copy genetic information; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4875,toxicity_endpoint,1108,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4876,toxicity_endpoint,1109,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4877,toxicity_endpoint,1110,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASO Drugs Targeting S‐COX11 Attenuate the Proliferative and Invasive Capabilities of Gastric Cancer Cells and Organoids; Figure 4 caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4878,toxicity_endpoint,1111,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4879,toxicity_endpoint,1112,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4880,toxicity_endpoint,1113,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Clinical variables; paragraph 32: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4881,toxicity_endpoint,1114,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 3: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4882,toxicity_endpoint,1115,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4883,toxicity_endpoint,1116,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4884,toxicity_endpoint,1117,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Stk25-Targeting ASO Therapy Hinders the Development and Progression of MASH-Related HCC in a Mouse Model; paragraph 16: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4885,toxicity_endpoint,1118,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > AEP activity is required for cell cycle progression and cell division in cancer cells; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4886,toxicity_endpoint,1119,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.1. Preparation and Characterization of the DMPLAC/siRNA Complex; paragraph 31: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4887,toxicity_endpoint,1120,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Baseline characteristics; paragraph 16: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4888,toxicity_endpoint,1121,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at article body; paragraph 5: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4889,toxicity_endpoint,1122,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > TUBB2B is required for TNBC spheroid growth and maintenance; paragraph 33: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4890,toxicity_endpoint,1123,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4891,toxicity_endpoint,1124,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Gene Silencing Effects of the ASO/CDs; paragraph 39: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4892,toxicity_endpoint,1125,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Clinical Evaluation of Bepirovirsen as DDI Perpetrator (Effect of Bepirovirsen on NA PK) in the B‐Clear Study > B‐Clear Study Design; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4893,toxicity_endpoint,1126,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > MYH Knockdown in PDAC cells induces DNA damage and cell cycle checkpoint activation; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4894,toxicity_endpoint,1127,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4895,toxicity_endpoint,1128,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Impact of phosphorus stereochemistry on safety; paragraph 19: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4896,toxicity_endpoint,1129,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Rictor-ASO treatment benefits lupus-like symptoms in MRL/lpr mice; paragraph 28: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4897,toxicity_endpoint,1130,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Screening and Filtration of Off‐Target Sites; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4898,toxicity_endpoint,1131,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.7. In Vivo Anticancer Activity and Safety Evaluation; paragraph 16: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4899,toxicity_endpoint,1132,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Endothelial-specific Mef2a knockdown recapitulates vascular oxidative pathology in vivo; paragraph 35: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4900,toxicity_endpoint,1133,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4901,toxicity_endpoint,1134,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > MZT2B silencing impedes viability, proliferation, migration, and induces cell cycle arrest in primary and immortalized NSCLC cells; paragraph 29: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4902,toxicity_endpoint,1135,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ImP Suppresses PI3K/AKT Signaling and Promotes Activation of Nuclear FOXO1; Figure 6. caption: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4903,toxicity_endpoint,1136,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4904,toxicity_endpoint,1137,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PRMT5 inhibition increases the sensitivity of TMZ in GBMNS; paragraph 24: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4905,toxicity_endpoint,1138,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4906,toxicity_endpoint,1139,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Cell Culture and Transfection; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4907,toxicity_endpoint,1140,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Role of the IKK‐NF‐κB Pathway in the Effects of TNF‐α on BKPyV; paragraph 24: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4908,toxicity_endpoint,1141,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Construction and characterization of the BRCA primary cell-derived engineered exosomes; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4909,toxicity_endpoint,1142,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4910,toxicity_endpoint,1143,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4911,toxicity_endpoint,1144,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety Summary; paragraph 26: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4912,toxicity_endpoint,1145,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Design of the study; paragraph 45: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4913,toxicity_endpoint,1146,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > The DOCK11-targeting gapmer transiently decreases DOCK11 expression but is insufficient to eliminate HBV cccDNA in vivo; paragraph 8: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4914,toxicity_endpoint,1147,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety profiles of the lead APOE and TREM2 ASOs; paragraph 68: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4915,toxicity_endpoint,1148,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4916,toxicity_endpoint,1149,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > PBPK modeling on in vivo disposition of RNA-LNP > Data collection; paragraph 10: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4917,toxicity_endpoint,1150,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Dystrophin restoration and improvement of histology by HDOs; paragraph 16: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4918,toxicity_endpoint,1151,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4919,toxicity_endpoint,1152,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Targeted delivery of mutant-specific ASOs via RBCEVs conjugated with EGFR-binding nanobodies enhances anti-cancer efficacy; paragraph 51: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4920,toxicity_endpoint,1153,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > In vivo tolerability testing of STAT6 3′ UTR-targeting ASOs; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4921,toxicity_endpoint,1154,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Evidence for R-loop toxicity upon expression of X. oryzae antisense region in E. coli; paragraph 75: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4922,toxicity_endpoint,1155,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 4. Discussion; paragraph 44: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4923,toxicity_endpoint,1156,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > The structure and chemical configuration of the siRNA affects the distribution pattern in mouse retinas; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4924,toxicity_endpoint,1157,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4925,toxicity_endpoint,1158,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > AKR1B1 affected BLCA cell viability, migration, and proliferation; paragraph 51: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4926,toxicity_endpoint,1159,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4927,toxicity_endpoint,1160,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.1. siRNA Screening Identifies Genes That Sensitizes the Anti-Proliferation of WIN 55212-2; paragraph 6: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4928,toxicity_endpoint,1161,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 3. Results > 3.4. Safety > Adverse Events; paragraph 37: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4929,toxicity_endpoint,1162,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4930,toxicity_endpoint,1163,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4931,toxicity_endpoint,1164,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 4: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4932,toxicity_endpoint,1165,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Study Population; paragraph 11: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4933,toxicity_endpoint,1166,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > Inhibition of KHK activity, but not its KD, leads to hepatic glycogen accumulation.; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4934,toxicity_endpoint,1167,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > siRNA-mediated knockdown; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4935,toxicity_endpoint,1168,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Small interference RNA or antisense RNA: alternative approaches to temporarily reduce the AGT expression in arterial hypertension; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4936,toxicity_endpoint,1169,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at DISCUSSION; paragraph 22: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4937,toxicity_endpoint,1170,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Rictor-ASO treatment benefits lupus-like symptoms in MRL/lpr mice.; paragraph 22: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4938,toxicity_endpoint,1171,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Histology and hematology; paragraph 36: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4939,toxicity_endpoint,1172,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Extensive screening identifies a potent chemically stabilized SOD1-targeting siRNA; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4940,toxicity_endpoint,1173,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4941,toxicity_endpoint,1174,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4942,toxicity_endpoint,1175,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > lincRNA-p21 targets scaffold protein KAP1 during cardiac hypertrophy; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4943,toxicity_endpoint,1176,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Overexpression of GS promotes CML cell resistant to Imatinib by perturbing cell cycle of CML cells via mTOR signaling pathway both in vitro and in vivo; paragraph 26: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4944,toxicity_endpoint,1177,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Depletion of the PLK1 gene exhibits antiproliferative effects on CCA cell lines; paragraph 23: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4945,toxicity_endpoint,1178,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4946,toxicity_endpoint,1179,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Cell viability assay; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4947,toxicity_endpoint,1180,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4948,toxicity_endpoint,1181,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4949,toxicity_endpoint,1182,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety; paragraph 18: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4950,toxicity_endpoint,1183,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.7. Cell Viability after Andiroba Seed Oil Treatment; paragraph 13: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4951,toxicity_endpoint,1184,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at METHODS > Animal studies; paragraph 21: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4952,toxicity_endpoint,1185,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4953,toxicity_endpoint,1186,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4954,toxicity_endpoint,1187,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Cell sensitivity and apoptosis assay; paragraph 6: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4955,toxicity_endpoint,1188,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > METHODS:; paragraph 2: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4956,toxicity_endpoint,1189,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Outcomes; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4957,toxicity_endpoint,1190,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > In vivo tumorigenesis and metastasis assays; paragraph 33: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4958,toxicity_endpoint,1191,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ILF2 ASOs induce DNA damage activation and enhance MM cells’ sensitivity to DNA-damaging agents; paragraph 8: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4959,toxicity_endpoint,1192,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Conclusion; paragraph 39: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4960,toxicity_endpoint,1193,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Transcriptome sequencing revealed impairment of DNA replication and repair pathways after silencing of c-Myc; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4961,toxicity_endpoint,1194,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4962,toxicity_endpoint,1195,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > The biological safety evaluation of tumor therapy; paragraph 60: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4963,toxicity_endpoint,1196,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4964,toxicity_endpoint,1197,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and Methods > Cell Cytotoxicity Assay; paragraph 27: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4965,toxicity_endpoint,1198,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > Multifunctional Validation of siRNA‐CaP@PD1‐NVs In Vitro; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4966,toxicity_endpoint,1199,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4967,toxicity_endpoint,1200,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Standard clinical laboratory tests > Liver; paragraph 19: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4968,toxicity_endpoint,1201,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Plasma Pharmacokinetics of N-Acetylgalactosamine (GalNAc)-Conjugated Small-Interfering Ribonucleic Acids (siRNAs) > Translation of Plasma Pharmacokinetics between Species; paragraph 15: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4969,toxicity_endpoint,1202,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and Methods > Treatment of mice with different AONs; paragraph 18: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4970,toxicity_endpoint,1203,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > RNA-seq reveals activation of the interferon response by all ASOs and additional off-target effects on gene expression by the repeat gapmer; paragraph 19: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4971,toxicity_endpoint,1204,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > In silico analysis of possible off-target effect of selected lead AON molecules; paragraph 31: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4972,toxicity_endpoint,1205,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Generation and pathophysiological characterization of G6PC c.648G>T–cKI mice.; paragraph 8: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4973,toxicity_endpoint,1206,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > Multivalent, Fully Chemically Stabilized siRNA Configurations Support Robust Lung Delivery, Distribution, and Target Gene Silencing.; paragraph 20: primary toxicity support for toxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
4974,toxicity_endpoint,1207,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at LESSONS FROM REGULATORY INTERACTIONS FOR INDIVIDUALIZED ASO DEVELOPMENT IN THE EUROPEAN UNION > Safety studies; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4975,toxicity_endpoint,1208,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > hERG siRNA tool molecules (KCNH2 siRNA): the positive control; paragraph 16: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4976,toxicity_endpoint,1209,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Materials and Methods > 2.1. Cell Culture and iPSC Differentiation to BMECs; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4977,toxicity_endpoint,1210,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASO-Ttbk1 selectively suppresses Ttbk1 expression in the temporal cortex of PS19 mice; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4978,toxicity_endpoint,1211,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > ISH detection of unlabeled bepirovirsen; FIGURE 2. caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4979,toxicity_endpoint,1212,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Primary endpoint of safety; paragraph 9: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4980,toxicity_endpoint,1213,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Depleted shRNAs reduce viability and growth of PCa cells and xenografts; paragraph 8: primary toxicity support for DNA damage response in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4981,toxicity_endpoint,1214,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > si3033 has a good safety profile and enables JAK1 silencing in mouse skin over 5 weeks; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4982,toxicity_endpoint,1215,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.1. PSPC1 Inhibition Synergizes with Olaparib in BRCA1/2-Mutated PSPC1-Expressing Cells; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4983,toxicity_endpoint,1216,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > G2019S pMac antigen presentation and lysosomal phenotypes are rescued by knockdown of Lrrk2; paragraph 19: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4984,toxicity_endpoint,1217,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Antisense oligonucleotide reduction of Tmem106b is safe in Wt and Grn +/− mice but toxic in Grn −/− mice; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4985,toxicity_endpoint,1218,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4986,toxicity_endpoint,1219,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Diets and diet composition; paragraph 16: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4987,toxicity_endpoint,1220,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4988,toxicity_endpoint,1221,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods & Results; paragraph 2: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4989,toxicity_endpoint,1222,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Safety and Toxicity; paragraph 16: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4990,toxicity_endpoint,1223,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > A canonical AUG initiation codon located 273 bp upstream of CCCCGG repeats is required for poly-PR synthesis; paragraph 10: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4991,toxicity_endpoint,1224,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Trial Design and Participants; paragraph 12: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4992,toxicity_endpoint,1225,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Biological function of GEMIN4 in BLBC cell lines; paragraph 27: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4993,toxicity_endpoint,1226,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4994,toxicity_endpoint,1227,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at MATERIALS AND METHODS > Data sources; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4995,toxicity_endpoint,1228,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > ASO-mediated targeting of MALAT1 has high “on-target” and low “off-target” specificity.; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4996,toxicity_endpoint,1229,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > DDX5 inhibition with ASO technology restores treatment sensitivity in CR cells; paragraph 18: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4997,toxicity_endpoint,1230,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4998,toxicity_endpoint,1231,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at C9ORF72 Disease Biology > Role of RNA Toxicity in C9ORF72-FTD/ALS; paragraph 21: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
4999,toxicity_endpoint,1232,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASO rescues FTH1 p.Ser164∗ variant cells; paragraph 35: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5000,toxicity_endpoint,1233,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5001,toxicity_endpoint,1234,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > In vivo genome editing in adult mouse liver by co-delivery of AAV-expressed effector and tracrRNA and GalNac-conjugated, self-delivering crRNA; paragraph 41: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
5002,toxicity_endpoint,1235,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Objectives; paragraph 1: primary toxicity support for thrombocytopenia in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5003,toxicity_endpoint,1236,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Material and methods > Preoperative data; paragraph 12: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5004,toxicity_endpoint,1237,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Results; paragraph 3: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5005,toxicity_endpoint,1238,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion > In Vitro RNAi Activity of siRNAs Modified with 2-F/Me Nucleotides; paragraph 21: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5006,toxicity_endpoint,1239,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > EFFICACY SECONDARY END POINTS and EXPLORATORY ANALYSES > Quality of Life Measures > Safety and Tolerability; paragraph 43: primary toxicity support for thrombocytopenia in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5007,toxicity_endpoint,1240,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Animal studies > Study 1; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5008,toxicity_endpoint,1241,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 4. Materials and Methods > 4.8. Cytotoxicity Assay (MTT Assay); paragraph 34: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5009,toxicity_endpoint,1242,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at PHASE II DESIGN AND ACCELERATION–STEP FIVE; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5010,toxicity_endpoint,1243,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > LNP encapsulated gE and CpG ODN induced cytokine responses at levels comparable to that boosted with Shingrix™; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5011,toxicity_endpoint,1244,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > PMOs, or Double-Stranded 2′ O-methyl Phosphorothioate AOs, Do Not Form Nuclear Inclusions, Protecting From Cellular Toxicity and Off-Target Transcript Effects; paragraph 53: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
5012,toxicity_endpoint,1245,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5013,toxicity_endpoint,1246,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > RBM3 suppression impairs sensitivity to chemotherapy in vitro; paragraph 28: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5014,toxicity_endpoint,1247,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Systematic chemical optimization of sFLT1-targeting siRNAs improves placental accumulation and degree of sFLT1 silencing with a better safety profile; paragraph 30: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5015,toxicity_endpoint,1248,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 36: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5016,toxicity_endpoint,1249,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Experimental methods > In vitro characterization of siRNA/VIPER polyplexes in a lung epithelial cell line > In vitro cytotoxicity in lung cells > Cell viability; paragraph 14: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5017,toxicity_endpoint,1250,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Short guide-strand bulges are well tolerated in unmodified siRNAs; paragraph 11: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5018,toxicity_endpoint,1251,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Safety profile of conjugated palm-tcDNA; paragraph 57: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5019,toxicity_endpoint,1252,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Preliminary laboratory validation of the key genes in a cell model of asthma; paragraph 33: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5020,toxicity_endpoint,1253,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Transient small interfering RNA transfection; paragraph 14: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5021,toxicity_endpoint,1254,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Inhibition of AKT reversed ketamine-induced mania-like behavior; paragraph 38: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5022,toxicity_endpoint,1255,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5023,toxicity_endpoint,1256,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5024,toxicity_endpoint,1257,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Safety and tolerability; paragraph 21: primary toxicity support for thrombocytopenia in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5025,toxicity_endpoint,1258,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Body > 2.2. Clinical Data on Volanesorsen Efficacy and Safety; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5026,toxicity_endpoint,1259,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > PSD3 downregulation reduces intracellular lipid accumulation; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5027,toxicity_endpoint,1260,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety analyses; paragraph 30: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5028,toxicity_endpoint,1261,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Safety evaluation; paragraph 25: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5029,toxicity_endpoint,1262,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5030,toxicity_endpoint,1263,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety and Tolerability; FIG. 3 caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5031,toxicity_endpoint,1264,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > TMEFF2-targeted shRNAs reduce cell viability and growth of PCa cells; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5032,toxicity_endpoint,1265,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > PS-ASO-binding can induce the interactions of RNase H1 with P54nrb and PSF proteins; paragraph 45: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5033,toxicity_endpoint,1266,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Characterization of the genetic circuits in vitro; paragraph 40: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5034,toxicity_endpoint,1267,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Systemic delivery of SRP-2001 in the LMNAG/G HGPS mouse model.; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5035,toxicity_endpoint,1268,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at MATERIALS AND METHODS > Evaluation of silencing in mice; paragraph 24: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5036,toxicity_endpoint,1269,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results; paragraph 26: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5037,toxicity_endpoint,1270,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > In vitro cytotoxicity assay; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5038,toxicity_endpoint,1271,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Methods > Study design; paragraph 39: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5039,toxicity_endpoint,1272,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Results > hnRNP L forms nuclear protein aggregates, and partially co-localizes with CUG repeats in the myoblasts of myotonic dystrophy patients.; paragraph 18: primary toxicity support for hepatotoxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
5040,toxicity_endpoint,1273,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Methods; paragraph 2: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5041,toxicity_endpoint,1274,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,"Verified full text evidence at Materials and Methods > Pilot PK Study, in Life Phase > Animal Groups and Size; paragraph 19: primary toxicity support for toxicity in an oligonucleotide context.",2026-06-02T15:59:55+00:00
5042,toxicity_endpoint,1275,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Pivotal GLP Rat Toxicity Study; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5043,toxicity_endpoint,1276,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and Methods > RNAi to Evaluate the Roles of TcCYP4BN6 and TcOBPC11 Response to the A. vulgaris EO; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5044,toxicity_endpoint,1277,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion > ASO treatment; paragraph 41: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5045,toxicity_endpoint,1278,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety and tolerability; paragraph 20: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5046,toxicity_endpoint,1279,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5047,toxicity_endpoint,1280,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Comparison of the efficacy of exon‐skipping and CRISPR‐Cas9 gene modification strategies; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5048,toxicity_endpoint,1281,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5049,toxicity_endpoint,1282,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract > Objectives and Methods; paragraph 2: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5050,toxicity_endpoint,1283,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Class IIa HDAC siRNA Knockdown in Mice Induced Morphological Changes in Spleen and Kidney; paragraph 37: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5051,toxicity_endpoint,1284,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5052,toxicity_endpoint,1285,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Patient Demographics and Baseline Characteristics; paragraph 23: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5053,toxicity_endpoint,1286,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety; paragraph 44: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5054,toxicity_endpoint,1287,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Ald-PGO Downregulates Ald Expression at the Translational Level; Figure 3 caption: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5055,toxicity_endpoint,1288,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Materials and methods > Screening and selection of murine Pnpla3 cEt 5′-GalNAc3-conjugated cEt ASOs; paragraph 11: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5056,toxicity_endpoint,1289,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results and Discussion; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5057,toxicity_endpoint,1290,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5058,toxicity_endpoint,1291,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > ASO-mediated reduction of eRF1 and eRF3a is well tolerated in mice; paragraph 15: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5059,toxicity_endpoint,1292,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5060,toxicity_endpoint,1293,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > Lipid-hsiRNAs elicit sustained systemic in vivo gene silencing after a single injection > Liver; paragraph 26: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5061,toxicity_endpoint,1294,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5062,toxicity_endpoint,1295,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > MCE modification reduced hepatotoxic potential; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5063,toxicity_endpoint,1296,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5064,toxicity_endpoint,1297,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Identification of Lead Oligonucleotide Targeting the CEP290 c.2991+1655A>G Mutation; paragraph 6: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5065,toxicity_endpoint,1298,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at RESULTS > SAFETY; paragraph 26: primary toxicity support for thrombocytopenia in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5066,toxicity_endpoint,1299,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at 2. Results > 2.2. Upregulation of SMN in SMA iPSCs; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5067,toxicity_endpoint,1300,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Discussion; paragraph 13: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5068,toxicity_endpoint,1301,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Establishment of an ASO-Based YB-1 Knockdown System; paragraph 5: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5069,toxicity_endpoint,1302,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Representative Results; paragraph 72: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5070,toxicity_endpoint,1303,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Safety; paragraph 47: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5071,toxicity_endpoint,1304,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > In vivo evaluation; paragraph 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5072,toxicity_endpoint,1305,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > 5. Toxicity studies; paragraph 47: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5073,toxicity_endpoint,1306,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at MATERIALS AND METHODS > In vivo anticancer efficacy; paragraph 31: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5074,toxicity_endpoint,1307,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > AON uptake and exon in mdx and mdx/utrn+/− mice; paragraph 7: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5075,toxicity_endpoint,1308,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5076,toxicity_endpoint,1309,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Results > Hepatotoxicity and nephrotoxicity in each siRNA-treated group; paragraph 17: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5077,toxicity_endpoint,1310,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified full text evidence at Abstract; paragraph 1: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5078,toxicity_endpoint,1311,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5079,toxicity_endpoint,1312,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5080,toxicity_endpoint,1313,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5081,toxicity_endpoint,1314,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5082,toxicity_endpoint,1315,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5083,toxicity_endpoint,1316,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5084,toxicity_endpoint,1317,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5085,toxicity_endpoint,1318,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5086,toxicity_endpoint,1319,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5087,toxicity_endpoint,1320,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5088,toxicity_endpoint,1321,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5089,toxicity_endpoint,1322,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5090,toxicity_endpoint,1323,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5091,toxicity_endpoint,1324,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5092,toxicity_endpoint,1325,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5093,toxicity_endpoint,1326,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5094,toxicity_endpoint,1327,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5095,toxicity_endpoint,1328,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5096,toxicity_endpoint,1329,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5097,toxicity_endpoint,1330,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5098,toxicity_endpoint,1331,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 5: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5099,toxicity_endpoint,1332,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5100,toxicity_endpoint,1333,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5101,toxicity_endpoint,1334,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5102,toxicity_endpoint,1335,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5103,toxicity_endpoint,1336,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5104,toxicity_endpoint,1337,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5105,toxicity_endpoint,1338,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5106,toxicity_endpoint,1339,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5107,toxicity_endpoint,1340,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for DNA damage response in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5108,toxicity_endpoint,1341,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5109,toxicity_endpoint,1342,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5110,toxicity_endpoint,1343,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5111,toxicity_endpoint,1344,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5112,toxicity_endpoint,1345,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5113,toxicity_endpoint,1346,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5114,toxicity_endpoint,1347,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5115,toxicity_endpoint,1348,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5116,toxicity_endpoint,1349,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5117,toxicity_endpoint,1350,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5118,toxicity_endpoint,1351,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5119,toxicity_endpoint,1352,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5120,toxicity_endpoint,1353,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5121,toxicity_endpoint,1354,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5122,toxicity_endpoint,1355,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5123,toxicity_endpoint,1356,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5124,toxicity_endpoint,1357,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5125,toxicity_endpoint,1358,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5126,toxicity_endpoint,1359,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5127,toxicity_endpoint,1360,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5128,toxicity_endpoint,1361,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 4: primary toxicity support for cell viability/cytotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5129,toxicity_endpoint,1362,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5130,toxicity_endpoint,1363,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5131,toxicity_endpoint,1364,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5132,toxicity_endpoint,1365,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5133,toxicity_endpoint,1366,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5134,toxicity_endpoint,1367,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5135,toxicity_endpoint,1368,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5136,toxicity_endpoint,1369,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5137,toxicity_endpoint,1370,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5138,toxicity_endpoint,1371,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5139,toxicity_endpoint,1372,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5140,toxicity_endpoint,1373,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5141,toxicity_endpoint,1374,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5142,toxicity_endpoint,1375,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 5: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5143,toxicity_endpoint,1376,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5144,toxicity_endpoint,1377,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5145,toxicity_endpoint,1378,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5146,toxicity_endpoint,1379,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5147,toxicity_endpoint,1380,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 8: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5148,toxicity_endpoint,1381,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5149,toxicity_endpoint,1382,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5150,toxicity_endpoint,1383,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5151,toxicity_endpoint,1384,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5152,toxicity_endpoint,1385,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5153,toxicity_endpoint,1386,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5154,toxicity_endpoint,1387,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5155,toxicity_endpoint,1388,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5156,toxicity_endpoint,1389,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5157,toxicity_endpoint,1390,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5158,toxicity_endpoint,1391,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5159,toxicity_endpoint,1392,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5160,toxicity_endpoint,1393,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5161,toxicity_endpoint,1394,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5162,toxicity_endpoint,1395,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5163,toxicity_endpoint,1396,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5164,toxicity_endpoint,1397,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5165,toxicity_endpoint,1398,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5166,toxicity_endpoint,1399,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5167,toxicity_endpoint,1400,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5168,toxicity_endpoint,1401,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5169,toxicity_endpoint,1402,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 4: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5170,toxicity_endpoint,1403,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 7: primary toxicity support for toxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5171,toxicity_endpoint,1404,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5172,toxicity_endpoint,1405,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5173,toxicity_endpoint,1406,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5174,toxicity_endpoint,1407,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5175,toxicity_endpoint,1408,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5176,toxicity_endpoint,1409,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5177,toxicity_endpoint,1410,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5178,toxicity_endpoint,1411,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 10: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5179,toxicity_endpoint,1412,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5180,toxicity_endpoint,1413,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5181,toxicity_endpoint,1414,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5182,toxicity_endpoint,1415,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5183,toxicity_endpoint,1416,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5184,toxicity_endpoint,1417,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for immune activation in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5185,toxicity_endpoint,1418,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5186,toxicity_endpoint,1419,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5187,toxicity_endpoint,1420,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5188,toxicity_endpoint,1421,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5189,toxicity_endpoint,1422,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5190,toxicity_endpoint,1423,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5191,toxicity_endpoint,1424,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5192,toxicity_endpoint,1425,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5193,toxicity_endpoint,1426,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5194,toxicity_endpoint,1427,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5195,toxicity_endpoint,1428,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for renal safety in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5196,toxicity_endpoint,1429,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for thrombocytopenia in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5197,toxicity_endpoint,1430,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5198,toxicity_endpoint,1431,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 15: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5199,toxicity_endpoint,1432,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 6: primary toxicity support for systemic safety/tolerability in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5200,toxicity_endpoint,1433,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5201,toxicity_endpoint,1434,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5202,toxicity_endpoint,1435,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5203,toxicity_endpoint,1436,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5204,toxicity_endpoint,1437,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5205,toxicity_endpoint,1438,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary toxicity support for hepatotoxicity in an oligonucleotide context.,2026-06-02T15:59:55+00:00
5206,curation_candidate,11895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5207,curation_candidate,12369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5208,curation_candidate,12514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5209,curation_candidate,12573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5210,curation_candidate,10312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5211,curation_candidate,11299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5212,curation_candidate,11327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5213,curation_candidate,11329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5214,curation_candidate,13642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5215,curation_candidate,13760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5216,curation_candidate,14037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5217,curation_candidate,10383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5218,curation_candidate,15792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5219,curation_candidate,15843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5220,curation_candidate,15897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5221,curation_candidate,15926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5222,curation_candidate,11624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5223,curation_candidate,15972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5224,curation_candidate,15981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5225,curation_candidate,16011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5226,curation_candidate,11039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5227,curation_candidate,15237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5228,curation_candidate,15238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5229,curation_candidate,16268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5230,curation_candidate,10400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5231,curation_candidate,10475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5232,curation_candidate,10519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5233,curation_candidate,10659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5234,curation_candidate,11872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5235,curation_candidate,12261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5236,curation_candidate,10352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5237,curation_candidate,10953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5238,curation_candidate,13434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5239,curation_candidate,13485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5240,curation_candidate,13933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5241,curation_candidate,14290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5242,curation_candidate,14328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5243,curation_candidate,14368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5244,curation_candidate,14425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5245,curation_candidate,14503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5246,curation_candidate,11021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5247,curation_candidate,15862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5248,curation_candidate,16110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5249,curation_candidate,15255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5250,curation_candidate,10307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5251,curation_candidate,10337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5252,curation_candidate,10372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5253,curation_candidate,10373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5254,curation_candidate,10374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5255,curation_candidate,10375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5256,curation_candidate,10384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5257,curation_candidate,10385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5258,curation_candidate,10391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5259,curation_candidate,10392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5260,curation_candidate,10401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5261,curation_candidate,10460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5262,curation_candidate,10483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5263,curation_candidate,10494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5264,curation_candidate,10496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5265,curation_candidate,10497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5266,curation_candidate,10499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5267,curation_candidate,10500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5268,curation_candidate,10501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5269,curation_candidate,10505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5270,curation_candidate,10507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5271,curation_candidate,10509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5272,curation_candidate,10513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5273,curation_candidate,10521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5274,curation_candidate,10526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5275,curation_candidate,10545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5276,curation_candidate,10615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5277,curation_candidate,10628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5278,curation_candidate,10635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5279,curation_candidate,10636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5280,curation_candidate,10644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5281,curation_candidate,10645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5282,curation_candidate,10650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5283,curation_candidate,10841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5284,curation_candidate,10842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5285,curation_candidate,10843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5286,curation_candidate,10844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5287,curation_candidate,10867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5288,curation_candidate,10931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5289,curation_candidate,10936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5290,curation_candidate,11087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5291,curation_candidate,11089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5292,curation_candidate,11091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5293,curation_candidate,11092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5294,curation_candidate,11137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5295,curation_candidate,11138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5296,curation_candidate,11146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5297,curation_candidate,11148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5298,curation_candidate,11151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5299,curation_candidate,11161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5300,curation_candidate,11162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5301,curation_candidate,11166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5302,curation_candidate,11176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5303,curation_candidate,11177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5304,curation_candidate,11179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5305,curation_candidate,11181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5306,curation_candidate,11184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5307,curation_candidate,11186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5308,curation_candidate,11190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5309,curation_candidate,11194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5310,curation_candidate,11198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5311,curation_candidate,11203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5312,curation_candidate,11205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5313,curation_candidate,11206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5314,curation_candidate,11213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5315,curation_candidate,11215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5316,curation_candidate,11217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5317,curation_candidate,11219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5318,curation_candidate,11221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5319,curation_candidate,11227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5320,curation_candidate,11229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5321,curation_candidate,11233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5322,curation_candidate,11241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5323,curation_candidate,11758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5324,curation_candidate,11774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5325,curation_candidate,11791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5326,curation_candidate,11794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5327,curation_candidate,11801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5328,curation_candidate,11805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5329,curation_candidate,11806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5330,curation_candidate,11807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5331,curation_candidate,11809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5332,curation_candidate,11810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5333,curation_candidate,11811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5334,curation_candidate,11812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5335,curation_candidate,11814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5336,curation_candidate,11816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5337,curation_candidate,11818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5338,curation_candidate,11830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5339,curation_candidate,11831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5340,curation_candidate,11832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5341,curation_candidate,11833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5342,curation_candidate,11838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5343,curation_candidate,11844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5344,curation_candidate,11846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5345,curation_candidate,11847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5346,curation_candidate,11850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5347,curation_candidate,11852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5348,curation_candidate,11878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5349,curation_candidate,11893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5350,curation_candidate,11898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5351,curation_candidate,11900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5352,curation_candidate,11915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5353,curation_candidate,11918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5354,curation_candidate,11922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5355,curation_candidate,11924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5356,curation_candidate,11930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5357,curation_candidate,11931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5358,curation_candidate,11945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5359,curation_candidate,11948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5360,curation_candidate,11949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5361,curation_candidate,11950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5362,curation_candidate,11959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5363,curation_candidate,11960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5364,curation_candidate,11974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5365,curation_candidate,11975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5366,curation_candidate,11976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5367,curation_candidate,11982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5368,curation_candidate,11984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5369,curation_candidate,11995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5370,curation_candidate,11996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5371,curation_candidate,12004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5372,curation_candidate,12006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5373,curation_candidate,12015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5374,curation_candidate,12018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5375,curation_candidate,12020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5376,curation_candidate,12021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5377,curation_candidate,12023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5378,curation_candidate,12028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5379,curation_candidate,12042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5380,curation_candidate,12045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5381,curation_candidate,12051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5382,curation_candidate,12052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5383,curation_candidate,12054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5384,curation_candidate,12057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5385,curation_candidate,12058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5386,curation_candidate,12060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5387,curation_candidate,12064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5388,curation_candidate,12066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5389,curation_candidate,12067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5390,curation_candidate,12076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5391,curation_candidate,12087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5392,curation_candidate,12090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5393,curation_candidate,12097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5394,curation_candidate,12103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5395,curation_candidate,12104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5396,curation_candidate,12105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5397,curation_candidate,12110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5398,curation_candidate,12111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5399,curation_candidate,12112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5400,curation_candidate,12113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5401,curation_candidate,12115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5402,curation_candidate,12116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5403,curation_candidate,12119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5404,curation_candidate,12121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5405,curation_candidate,12131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5406,curation_candidate,12136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5407,curation_candidate,12143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5408,curation_candidate,12149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5409,curation_candidate,12164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5410,curation_candidate,12171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5411,curation_candidate,12173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5412,curation_candidate,12174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5413,curation_candidate,12195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5414,curation_candidate,12198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5415,curation_candidate,12199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5416,curation_candidate,12202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5417,curation_candidate,12206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5418,curation_candidate,12214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5419,curation_candidate,12215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5420,curation_candidate,12216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5421,curation_candidate,12217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5422,curation_candidate,12223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5423,curation_candidate,12225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5424,curation_candidate,12226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5425,curation_candidate,12230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5426,curation_candidate,12231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5427,curation_candidate,12232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5428,curation_candidate,12233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5429,curation_candidate,12235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5430,curation_candidate,12237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5431,curation_candidate,12242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5432,curation_candidate,12245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5433,curation_candidate,12268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5434,curation_candidate,12270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5435,curation_candidate,12274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5436,curation_candidate,12275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5437,curation_candidate,12278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5438,curation_candidate,12279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5439,curation_candidate,12280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5440,curation_candidate,12281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5441,curation_candidate,12283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5442,curation_candidate,12299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5443,curation_candidate,12307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5444,curation_candidate,12308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5445,curation_candidate,12321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5446,curation_candidate,12330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5447,curation_candidate,12333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5448,curation_candidate,12336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5449,curation_candidate,12343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5450,curation_candidate,12346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5451,curation_candidate,12347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5452,curation_candidate,12349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5453,curation_candidate,12350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5454,curation_candidate,12351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5455,curation_candidate,12352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5456,curation_candidate,12353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5457,curation_candidate,12354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5458,curation_candidate,12355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5459,curation_candidate,12358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5460,curation_candidate,12360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5461,curation_candidate,12361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5462,curation_candidate,12372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5463,curation_candidate,12373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5464,curation_candidate,12379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5465,curation_candidate,12381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5466,curation_candidate,12383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5467,curation_candidate,12385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5468,curation_candidate,12387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5469,curation_candidate,12388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5470,curation_candidate,12390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5471,curation_candidate,12393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5472,curation_candidate,12406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5473,curation_candidate,12407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5474,curation_candidate,12411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5475,curation_candidate,12412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5476,curation_candidate,12416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5477,curation_candidate,12419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5478,curation_candidate,12421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5479,curation_candidate,12424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5480,curation_candidate,12437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5481,curation_candidate,12444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5482,curation_candidate,12445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5483,curation_candidate,12456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5484,curation_candidate,12457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5485,curation_candidate,12461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5486,curation_candidate,12462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5487,curation_candidate,12464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5488,curation_candidate,12465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5489,curation_candidate,12468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5490,curation_candidate,12478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5491,curation_candidate,12479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5492,curation_candidate,12480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5493,curation_candidate,12483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5494,curation_candidate,12490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5495,curation_candidate,12492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5496,curation_candidate,12493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5497,curation_candidate,12515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5498,curation_candidate,12516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5499,curation_candidate,12517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5500,curation_candidate,12519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5501,curation_candidate,12520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5502,curation_candidate,12527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5503,curation_candidate,12528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5504,curation_candidate,12529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5505,curation_candidate,12532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5506,curation_candidate,12535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5507,curation_candidate,12543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5508,curation_candidate,12546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5509,curation_candidate,12549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5510,curation_candidate,12556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5511,curation_candidate,12558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5512,curation_candidate,12559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5513,curation_candidate,12561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5514,curation_candidate,12570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5515,curation_candidate,12572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5516,curation_candidate,12574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5517,curation_candidate,12578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5518,curation_candidate,12580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5519,curation_candidate,12582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5520,curation_candidate,12584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5521,curation_candidate,12586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5522,curation_candidate,12590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5523,curation_candidate,12595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5524,curation_candidate,12596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5525,curation_candidate,12608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5526,curation_candidate,12611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5527,curation_candidate,12613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5528,curation_candidate,12615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5529,curation_candidate,12616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5530,curation_candidate,12617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5531,curation_candidate,12625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5532,curation_candidate,12633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5533,curation_candidate,12634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5534,curation_candidate,12635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5535,curation_candidate,12637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5536,curation_candidate,12640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5537,curation_candidate,12641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5538,curation_candidate,12643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5539,curation_candidate,12648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5540,curation_candidate,12650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5541,curation_candidate,12653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5542,curation_candidate,12659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5543,curation_candidate,12662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5544,curation_candidate,12668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5545,curation_candidate,12672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5546,curation_candidate,12683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5547,curation_candidate,12685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5548,curation_candidate,12686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5549,curation_candidate,12687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5550,curation_candidate,12690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5551,curation_candidate,12692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5552,curation_candidate,12694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5553,curation_candidate,12696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5554,curation_candidate,12706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5555,curation_candidate,12709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5556,curation_candidate,12711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5557,curation_candidate,12712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5558,curation_candidate,12722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5559,curation_candidate,12725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5560,curation_candidate,12727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5561,curation_candidate,12729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5562,curation_candidate,12735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5563,curation_candidate,12738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5564,curation_candidate,12742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5565,curation_candidate,12743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5566,curation_candidate,12746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5567,curation_candidate,12759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5568,curation_candidate,12761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5569,curation_candidate,12767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5570,curation_candidate,12770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5571,curation_candidate,12771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5572,curation_candidate,12773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5573,curation_candidate,12781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5574,curation_candidate,12784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5575,curation_candidate,12786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5576,curation_candidate,12789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5577,curation_candidate,12791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5578,curation_candidate,12793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5579,curation_candidate,12796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5580,curation_candidate,12800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5581,curation_candidate,12801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5582,curation_candidate,12802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5583,curation_candidate,12806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5584,curation_candidate,12815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5585,curation_candidate,12820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5586,curation_candidate,12827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5587,curation_candidate,12834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5588,curation_candidate,12841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5589,curation_candidate,12844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5590,curation_candidate,12846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5591,curation_candidate,12848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5592,curation_candidate,12849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5593,curation_candidate,12851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5594,curation_candidate,12857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5595,curation_candidate,12858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5596,curation_candidate,12861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5597,curation_candidate,12868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5598,curation_candidate,12879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5599,curation_candidate,12880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5600,curation_candidate,12889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5601,curation_candidate,12891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5602,curation_candidate,12895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5603,curation_candidate,12903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5604,curation_candidate,12912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5605,curation_candidate,12922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5606,curation_candidate,12928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5607,curation_candidate,12933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5608,curation_candidate,12961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5609,curation_candidate,12977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5610,curation_candidate,12985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5611,curation_candidate,12989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5612,curation_candidate,12993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5613,curation_candidate,13021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5614,curation_candidate,13022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5615,curation_candidate,13029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5616,curation_candidate,13031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5617,curation_candidate,13058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5618,curation_candidate,13062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5619,curation_candidate,13076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5620,curation_candidate,13077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5621,curation_candidate,13088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5622,curation_candidate,13098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5623,curation_candidate,13100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5624,curation_candidate,13102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5625,curation_candidate,15099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5626,curation_candidate,15144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5627,curation_candidate,15305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5628,curation_candidate,15309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5629,curation_candidate,15310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5630,curation_candidate,15311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5631,curation_candidate,15313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5632,curation_candidate,15316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5633,curation_candidate,15320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5634,curation_candidate,15328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5635,curation_candidate,15330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5636,curation_candidate,15333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5637,curation_candidate,15334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5638,curation_candidate,15335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5639,curation_candidate,15336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5640,curation_candidate,15339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5641,curation_candidate,15340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5642,curation_candidate,15341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5643,curation_candidate,15342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5644,curation_candidate,15345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5645,curation_candidate,15349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5646,curation_candidate,15350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5647,curation_candidate,15351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5648,curation_candidate,15352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5649,curation_candidate,15353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5650,curation_candidate,15354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5651,curation_candidate,15372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5652,curation_candidate,15375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5653,curation_candidate,15379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5654,curation_candidate,15388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5655,curation_candidate,10330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5656,curation_candidate,10335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5657,curation_candidate,10353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5658,curation_candidate,10358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5659,curation_candidate,10376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5660,curation_candidate,10417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5661,curation_candidate,10419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5662,curation_candidate,10421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5663,curation_candidate,10426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5664,curation_candidate,10428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5665,curation_candidate,10436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5666,curation_candidate,10556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5667,curation_candidate,10662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5668,curation_candidate,10663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5669,curation_candidate,10668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5670,curation_candidate,10673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5671,curation_candidate,10674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5672,curation_candidate,10675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5673,curation_candidate,10678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5674,curation_candidate,10680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5675,curation_candidate,10681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5676,curation_candidate,10686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5677,curation_candidate,10690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5678,curation_candidate,10692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5679,curation_candidate,10698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5680,curation_candidate,10701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5681,curation_candidate,10706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5682,curation_candidate,10708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5683,curation_candidate,10709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5684,curation_candidate,10711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5685,curation_candidate,10717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5686,curation_candidate,10723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5687,curation_candidate,10724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5688,curation_candidate,10725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5689,curation_candidate,10837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5690,curation_candidate,10859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5691,curation_candidate,10869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5692,curation_candidate,10872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5693,curation_candidate,10873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5694,curation_candidate,10874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5695,curation_candidate,10876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5696,curation_candidate,10941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5697,curation_candidate,10942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5698,curation_candidate,10943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5699,curation_candidate,10950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5700,curation_candidate,10952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5701,curation_candidate,10958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5702,curation_candidate,10962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5703,curation_candidate,10963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5704,curation_candidate,10964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5705,curation_candidate,10968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5706,curation_candidate,10969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5707,curation_candidate,10970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5708,curation_candidate,10973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5709,curation_candidate,11095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5710,curation_candidate,11097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5711,curation_candidate,11099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5712,curation_candidate,11100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5713,curation_candidate,11101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5714,curation_candidate,11103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5715,curation_candidate,11104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5716,curation_candidate,11110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5717,curation_candidate,11254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5718,curation_candidate,11257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5719,curation_candidate,11260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5720,curation_candidate,11261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5721,curation_candidate,11263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5722,curation_candidate,11269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5723,curation_candidate,11270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5724,curation_candidate,11271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5725,curation_candidate,11272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5726,curation_candidate,11274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5727,curation_candidate,11275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5728,curation_candidate,11280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5729,curation_candidate,11286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5730,curation_candidate,11287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5731,curation_candidate,11295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5732,curation_candidate,11296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5733,curation_candidate,11301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5734,curation_candidate,11304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5735,curation_candidate,11306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5736,curation_candidate,11311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5737,curation_candidate,11312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5738,curation_candidate,11317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5739,curation_candidate,11318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5740,curation_candidate,11319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5741,curation_candidate,11322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5742,curation_candidate,11324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5743,curation_candidate,11326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5744,curation_candidate,11328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5745,curation_candidate,11332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5746,curation_candidate,11335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5747,curation_candidate,11338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5748,curation_candidate,11339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5749,curation_candidate,11341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5750,curation_candidate,11346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5751,curation_candidate,11347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5752,curation_candidate,11349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5753,curation_candidate,11350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: computational source lacks concrete off-target evidence,2026-06-02T15:59:55+00:00
5754,curation_candidate,11352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5755,curation_candidate,11353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5756,curation_candidate,11356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5757,curation_candidate,11357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5758,curation_candidate,11360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5759,curation_candidate,11365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5760,curation_candidate,11381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5761,curation_candidate,11384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5762,curation_candidate,11385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5763,curation_candidate,11390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5764,curation_candidate,11392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5765,curation_candidate,11393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5766,curation_candidate,11394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5767,curation_candidate,11396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5768,curation_candidate,11400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5769,curation_candidate,11401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5770,curation_candidate,11406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5771,curation_candidate,11408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5772,curation_candidate,11410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5773,curation_candidate,11412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5774,curation_candidate,11415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5775,curation_candidate,11417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5776,curation_candidate,11423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5777,curation_candidate,11428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5778,curation_candidate,11438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5779,curation_candidate,11440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5780,curation_candidate,11441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5781,curation_candidate,11447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5782,curation_candidate,11449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5783,curation_candidate,11465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5784,curation_candidate,11469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5785,curation_candidate,13108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5786,curation_candidate,13112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5787,curation_candidate,13113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5788,curation_candidate,13114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5789,curation_candidate,13116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5790,curation_candidate,13117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5791,curation_candidate,13119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5792,curation_candidate,13120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5793,curation_candidate,13122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5794,curation_candidate,13123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5795,curation_candidate,13126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5796,curation_candidate,13127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5797,curation_candidate,13128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5798,curation_candidate,13129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5799,curation_candidate,13130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5800,curation_candidate,13131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5801,curation_candidate,13132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5802,curation_candidate,13133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5803,curation_candidate,13134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5804,curation_candidate,13135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5805,curation_candidate,13137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5806,curation_candidate,13141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5807,curation_candidate,13142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5808,curation_candidate,13143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5809,curation_candidate,13145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5810,curation_candidate,13146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5811,curation_candidate,13151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5812,curation_candidate,13152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5813,curation_candidate,13153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5814,curation_candidate,13156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5815,curation_candidate,13157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5816,curation_candidate,13164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5817,curation_candidate,13166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5818,curation_candidate,13167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5819,curation_candidate,13168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5820,curation_candidate,13169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5821,curation_candidate,13171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5822,curation_candidate,13172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5823,curation_candidate,13177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5824,curation_candidate,13178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5825,curation_candidate,13181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5826,curation_candidate,13183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5827,curation_candidate,13187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5828,curation_candidate,13193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5829,curation_candidate,13195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5830,curation_candidate,13196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5831,curation_candidate,13197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5832,curation_candidate,13199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5833,curation_candidate,13202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5834,curation_candidate,13203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5835,curation_candidate,13204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5836,curation_candidate,13206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5837,curation_candidate,13207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5838,curation_candidate,13212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5839,curation_candidate,13213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5840,curation_candidate,13215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5841,curation_candidate,13218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5842,curation_candidate,13220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5843,curation_candidate,13221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5844,curation_candidate,13223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5845,curation_candidate,13224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5846,curation_candidate,13225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5847,curation_candidate,13227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5848,curation_candidate,13230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5849,curation_candidate,13234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5850,curation_candidate,13236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5851,curation_candidate,13237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5852,curation_candidate,13238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5853,curation_candidate,13240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5854,curation_candidate,13244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5855,curation_candidate,13248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5856,curation_candidate,13249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5857,curation_candidate,13250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5858,curation_candidate,13252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5859,curation_candidate,13255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5860,curation_candidate,13257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5861,curation_candidate,13260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5862,curation_candidate,13261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5863,curation_candidate,13263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5864,curation_candidate,13268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5865,curation_candidate,13269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5866,curation_candidate,13270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5867,curation_candidate,13271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5868,curation_candidate,13277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5869,curation_candidate,13278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5870,curation_candidate,13280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5871,curation_candidate,13283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5872,curation_candidate,13284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5873,curation_candidate,13287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5874,curation_candidate,13288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5875,curation_candidate,13292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5876,curation_candidate,13298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5877,curation_candidate,13302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5878,curation_candidate,13303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5879,curation_candidate,13306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5880,curation_candidate,13307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5881,curation_candidate,13309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5882,curation_candidate,13310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5883,curation_candidate,13311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5884,curation_candidate,13314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5885,curation_candidate,13317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5886,curation_candidate,13318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5887,curation_candidate,13320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5888,curation_candidate,13326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5889,curation_candidate,13329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5890,curation_candidate,13330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5891,curation_candidate,13332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5892,curation_candidate,13334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5893,curation_candidate,13337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5894,curation_candidate,13339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5895,curation_candidate,13346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5896,curation_candidate,13349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5897,curation_candidate,13351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5898,curation_candidate,13354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5899,curation_candidate,13355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5900,curation_candidate,13356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5901,curation_candidate,13363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5902,curation_candidate,13364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5903,curation_candidate,13366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5904,curation_candidate,13367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5905,curation_candidate,13375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5906,curation_candidate,13379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5907,curation_candidate,13381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5908,curation_candidate,13383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5909,curation_candidate,13388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5910,curation_candidate,13390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5911,curation_candidate,13391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5912,curation_candidate,13392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5913,curation_candidate,13394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5914,curation_candidate,13395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5915,curation_candidate,13398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5916,curation_candidate,13406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5917,curation_candidate,13411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5918,curation_candidate,13416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5919,curation_candidate,13417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5920,curation_candidate,13421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5921,curation_candidate,13422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5922,curation_candidate,13424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5923,curation_candidate,13438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5924,curation_candidate,13441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5925,curation_candidate,13444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5926,curation_candidate,13445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
5927,curation_candidate,13452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5928,curation_candidate,13457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5929,curation_candidate,13468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5930,curation_candidate,13470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5931,curation_candidate,13471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5932,curation_candidate,13473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5933,curation_candidate,13475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5934,curation_candidate,13477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5935,curation_candidate,13481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5936,curation_candidate,13488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5937,curation_candidate,13489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5938,curation_candidate,13493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5939,curation_candidate,13496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
5940,curation_candidate,13498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5941,curation_candidate,13504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5942,curation_candidate,13508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5943,curation_candidate,13509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5944,curation_candidate,13511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5945,curation_candidate,13512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5946,curation_candidate,13514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5947,curation_candidate,13515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5948,curation_candidate,13516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5949,curation_candidate,13519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5950,curation_candidate,13522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5951,curation_candidate,13524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5952,curation_candidate,13525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5953,curation_candidate,13526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
5954,curation_candidate,13531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5955,curation_candidate,13533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5956,curation_candidate,13536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5957,curation_candidate,13537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5958,curation_candidate,13540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5959,curation_candidate,13547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5960,curation_candidate,13550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5961,curation_candidate,13551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5962,curation_candidate,13552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5963,curation_candidate,13557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5964,curation_candidate,13559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5965,curation_candidate,13566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5966,curation_candidate,13568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5967,curation_candidate,13570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5968,curation_candidate,13578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5969,curation_candidate,13595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5970,curation_candidate,13611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5971,curation_candidate,13612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5972,curation_candidate,13616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
5973,curation_candidate,13618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
5974,curation_candidate,13619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5975,curation_candidate,13622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5976,curation_candidate,13623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5977,curation_candidate,13628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5978,curation_candidate,13633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5979,curation_candidate,13635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5980,curation_candidate,13645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5981,curation_candidate,13647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5982,curation_candidate,13649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5983,curation_candidate,13653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5984,curation_candidate,13654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5985,curation_candidate,13658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5986,curation_candidate,13659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5987,curation_candidate,13660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5988,curation_candidate,13661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5989,curation_candidate,13663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
5990,curation_candidate,13665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5991,curation_candidate,13675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5992,curation_candidate,13682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
5993,curation_candidate,13684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5994,curation_candidate,13685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5995,curation_candidate,13686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5996,curation_candidate,13688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
5997,curation_candidate,13704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
5998,curation_candidate,13706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
5999,curation_candidate,13709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6000,curation_candidate,13710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6001,curation_candidate,13713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6002,curation_candidate,13716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6003,curation_candidate,13729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6004,curation_candidate,13733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6005,curation_candidate,13745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6006,curation_candidate,13748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6007,curation_candidate,13750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6008,curation_candidate,13754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6009,curation_candidate,13768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6010,curation_candidate,13770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6011,curation_candidate,13771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6012,curation_candidate,13772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6013,curation_candidate,13777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6014,curation_candidate,13781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6015,curation_candidate,13783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6016,curation_candidate,13786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6017,curation_candidate,13787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6018,curation_candidate,13796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6019,curation_candidate,13799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6020,curation_candidate,13802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6021,curation_candidate,13803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6022,curation_candidate,13805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6023,curation_candidate,13810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6024,curation_candidate,13811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
6025,curation_candidate,13816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6026,curation_candidate,13817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6027,curation_candidate,13820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6028,curation_candidate,13821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6029,curation_candidate,13826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6030,curation_candidate,13830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6031,curation_candidate,13847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6032,curation_candidate,13858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6033,curation_candidate,13860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6034,curation_candidate,13865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6035,curation_candidate,13871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6036,curation_candidate,13872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6037,curation_candidate,13876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6038,curation_candidate,13877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6039,curation_candidate,13893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6040,curation_candidate,13895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6041,curation_candidate,13898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6042,curation_candidate,13902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6043,curation_candidate,13903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6044,curation_candidate,13905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6045,curation_candidate,13912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6046,curation_candidate,13914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6047,curation_candidate,13924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6048,curation_candidate,13929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6049,curation_candidate,13930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6050,curation_candidate,13938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6051,curation_candidate,13939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6052,curation_candidate,13943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6053,curation_candidate,13944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6054,curation_candidate,13945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6055,curation_candidate,13946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6056,curation_candidate,13948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6057,curation_candidate,13949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6058,curation_candidate,13953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6059,curation_candidate,13954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6060,curation_candidate,13955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6061,curation_candidate,13956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6062,curation_candidate,13967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6063,curation_candidate,13968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6064,curation_candidate,13971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6065,curation_candidate,13974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6066,curation_candidate,13975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6067,curation_candidate,13976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6068,curation_candidate,13981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6069,curation_candidate,13984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6070,curation_candidate,13988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6071,curation_candidate,13996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6072,curation_candidate,13997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6073,curation_candidate,13998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6074,curation_candidate,14005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6075,curation_candidate,14007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6076,curation_candidate,14008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6077,curation_candidate,14010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6078,curation_candidate,14019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6079,curation_candidate,14026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6080,curation_candidate,14029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6081,curation_candidate,14034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6082,curation_candidate,14039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6083,curation_candidate,14040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6084,curation_candidate,14043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6085,curation_candidate,14045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6086,curation_candidate,14049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6087,curation_candidate,14050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6088,curation_candidate,14055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6089,curation_candidate,14061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6090,curation_candidate,14067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6091,curation_candidate,14075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6092,curation_candidate,14079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6093,curation_candidate,14088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6094,curation_candidate,14090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6095,curation_candidate,14092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6096,curation_candidate,14093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6097,curation_candidate,14095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6098,curation_candidate,14097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6099,curation_candidate,14102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6100,curation_candidate,14104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6101,curation_candidate,14105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6102,curation_candidate,14112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6103,curation_candidate,14114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6104,curation_candidate,14118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6105,curation_candidate,14123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6106,curation_candidate,14126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6107,curation_candidate,14127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6108,curation_candidate,14132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6109,curation_candidate,14134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6110,curation_candidate,14154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6111,curation_candidate,14156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6112,curation_candidate,14162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6113,curation_candidate,14168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6114,curation_candidate,14174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6115,curation_candidate,14177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6116,curation_candidate,14178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6117,curation_candidate,14182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6118,curation_candidate,14193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6119,curation_candidate,14198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6120,curation_candidate,14200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6121,curation_candidate,14204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6122,curation_candidate,14205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6123,curation_candidate,14207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6124,curation_candidate,14212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6125,curation_candidate,14213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6126,curation_candidate,14215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6127,curation_candidate,14217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6128,curation_candidate,14219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6129,curation_candidate,14227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6130,curation_candidate,14229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6131,curation_candidate,14231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6132,curation_candidate,14236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6133,curation_candidate,14239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6134,curation_candidate,14244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6135,curation_candidate,14245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6136,curation_candidate,14249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6137,curation_candidate,14250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6138,curation_candidate,14256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6139,curation_candidate,14258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6140,curation_candidate,14266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6141,curation_candidate,14268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6142,curation_candidate,14273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6143,curation_candidate,14275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6144,curation_candidate,14277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6145,curation_candidate,14280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6146,curation_candidate,14284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6147,curation_candidate,14295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6148,curation_candidate,14298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6149,curation_candidate,14300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6150,curation_candidate,14301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6151,curation_candidate,14304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6152,curation_candidate,14308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6153,curation_candidate,14309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6154,curation_candidate,14313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6155,curation_candidate,14320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6156,curation_candidate,14322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6157,curation_candidate,14324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6158,curation_candidate,14327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6159,curation_candidate,14330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6160,curation_candidate,14333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6161,curation_candidate,14339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6162,curation_candidate,14342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6163,curation_candidate,14345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6164,curation_candidate,14346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6165,curation_candidate,14356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6166,curation_candidate,14362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6167,curation_candidate,14364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6168,curation_candidate,14369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6169,curation_candidate,14376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6170,curation_candidate,14378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6171,curation_candidate,14382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6172,curation_candidate,14385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6173,curation_candidate,14403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6174,curation_candidate,14408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6175,curation_candidate,14409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6176,curation_candidate,14436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6177,curation_candidate,15127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6178,curation_candidate,15130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6179,curation_candidate,15131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6180,curation_candidate,15147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6181,curation_candidate,15149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6182,curation_candidate,15157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6183,curation_candidate,15163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6184,curation_candidate,15164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: computational source lacks concrete off-target evidence,2026-06-02T15:59:55+00:00
6185,curation_candidate,15168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6186,curation_candidate,15172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6187,curation_candidate,15174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6188,curation_candidate,15183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6189,curation_candidate,15389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6190,curation_candidate,15391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6191,curation_candidate,15395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6192,curation_candidate,15397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6193,curation_candidate,15398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6194,curation_candidate,15401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6195,curation_candidate,15409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6196,curation_candidate,15416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6197,curation_candidate,15418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6198,curation_candidate,15426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6199,curation_candidate,15428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6200,curation_candidate,15429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6201,curation_candidate,15431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6202,curation_candidate,15433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6203,curation_candidate,15435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6204,curation_candidate,15436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6205,curation_candidate,15438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6206,curation_candidate,15439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6207,curation_candidate,15442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6208,curation_candidate,15447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6209,curation_candidate,15451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6210,curation_candidate,15456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6211,curation_candidate,15457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6212,curation_candidate,15461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6213,curation_candidate,15462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6214,curation_candidate,15463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6215,curation_candidate,15464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6216,curation_candidate,15466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6217,curation_candidate,15468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6218,curation_candidate,15469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6219,curation_candidate,15473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6220,curation_candidate,15479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6221,curation_candidate,15480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6222,curation_candidate,15482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6223,curation_candidate,15483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6224,curation_candidate,15485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6225,curation_candidate,15486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6226,curation_candidate,15490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6227,curation_candidate,15495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6228,curation_candidate,15498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6229,curation_candidate,15503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6230,curation_candidate,15505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6231,curation_candidate,15506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6232,curation_candidate,15509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6233,curation_candidate,15510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6234,curation_candidate,15513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6235,curation_candidate,15516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6236,curation_candidate,15517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6237,curation_candidate,15519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6238,curation_candidate,15520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6239,curation_candidate,15523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6240,curation_candidate,15527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6241,curation_candidate,15534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6242,curation_candidate,15540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6243,curation_candidate,15541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6244,curation_candidate,15542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6245,curation_candidate,15544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6246,curation_candidate,15550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6247,curation_candidate,15558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6248,curation_candidate,15564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6249,curation_candidate,15566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6250,curation_candidate,15571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6251,curation_candidate,15573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6252,curation_candidate,15581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6253,curation_candidate,15584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6254,curation_candidate,15590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6255,curation_candidate,15595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6256,curation_candidate,15596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6257,curation_candidate,15601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6258,curation_candidate,15630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6259,curation_candidate,10309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6260,curation_candidate,10360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6261,curation_candidate,10366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6262,curation_candidate,10515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6263,curation_candidate,10559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6264,curation_candidate,10746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6265,curation_candidate,10748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6266,curation_candidate,10764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6267,curation_candidate,10861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6268,curation_candidate,10976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6269,curation_candidate,10979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6270,curation_candidate,10980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6271,curation_candidate,10987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6272,curation_candidate,11001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6273,curation_candidate,11115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6274,curation_candidate,11472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6275,curation_candidate,11473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6276,curation_candidate,11474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6277,curation_candidate,11475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6278,curation_candidate,11476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6279,curation_candidate,11477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6280,curation_candidate,11487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6281,curation_candidate,11488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6282,curation_candidate,11492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6283,curation_candidate,11493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6284,curation_candidate,11501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6285,curation_candidate,11507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6286,curation_candidate,11508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6287,curation_candidate,11512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6288,curation_candidate,11519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6289,curation_candidate,11522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6290,curation_candidate,11523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6291,curation_candidate,11525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6292,curation_candidate,11527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6293,curation_candidate,11541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6294,curation_candidate,11556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6295,curation_candidate,11557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6296,curation_candidate,14440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6297,curation_candidate,14441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6298,curation_candidate,14442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6299,curation_candidate,14443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6300,curation_candidate,14447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6301,curation_candidate,14448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6302,curation_candidate,14449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6303,curation_candidate,14452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6304,curation_candidate,14454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6305,curation_candidate,14455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6306,curation_candidate,14458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6307,curation_candidate,14463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6308,curation_candidate,14465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6309,curation_candidate,14469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6310,curation_candidate,14471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6311,curation_candidate,14473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6312,curation_candidate,14475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6313,curation_candidate,14476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6314,curation_candidate,14482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6315,curation_candidate,14496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6316,curation_candidate,14511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6317,curation_candidate,14513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6318,curation_candidate,14515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6319,curation_candidate,14516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6320,curation_candidate,14520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6321,curation_candidate,14524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6322,curation_candidate,14526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6323,curation_candidate,14528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6324,curation_candidate,14530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6325,curation_candidate,14533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6326,curation_candidate,14534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6327,curation_candidate,14535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6328,curation_candidate,14536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6329,curation_candidate,14538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6330,curation_candidate,14545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6331,curation_candidate,14546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6332,curation_candidate,14550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6333,curation_candidate,14554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6334,curation_candidate,14558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6335,curation_candidate,14561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6336,curation_candidate,14567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6337,curation_candidate,14568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
6338,curation_candidate,14569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6339,curation_candidate,14570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6340,curation_candidate,14571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6341,curation_candidate,14575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6342,curation_candidate,14576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
6343,curation_candidate,14578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6344,curation_candidate,14581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6345,curation_candidate,14584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6346,curation_candidate,14586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6347,curation_candidate,14588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6348,curation_candidate,14591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6349,curation_candidate,14595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6350,curation_candidate,14597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6351,curation_candidate,14599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6352,curation_candidate,14600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6353,curation_candidate,14605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6354,curation_candidate,14606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6355,curation_candidate,14608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6356,curation_candidate,14610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6357,curation_candidate,14620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6358,curation_candidate,14628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6359,curation_candidate,14629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6360,curation_candidate,14633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6361,curation_candidate,14635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6362,curation_candidate,14639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6363,curation_candidate,14652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6364,curation_candidate,14653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6365,curation_candidate,14656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6366,curation_candidate,14658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6367,curation_candidate,14661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6368,curation_candidate,14662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6369,curation_candidate,14666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6370,curation_candidate,14667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6371,curation_candidate,14669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6372,curation_candidate,14677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6373,curation_candidate,14679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6374,curation_candidate,14683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6375,curation_candidate,14685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6376,curation_candidate,14694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6377,curation_candidate,14696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6378,curation_candidate,14701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6379,curation_candidate,14710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6380,curation_candidate,14720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6381,curation_candidate,14722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6382,curation_candidate,14724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6383,curation_candidate,14729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6384,curation_candidate,14730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6385,curation_candidate,14734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6386,curation_candidate,14740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6387,curation_candidate,14749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6388,curation_candidate,14750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6389,curation_candidate,14752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6390,curation_candidate,14763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6391,curation_candidate,14764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6392,curation_candidate,14765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6393,curation_candidate,14774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6394,curation_candidate,14778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6395,curation_candidate,14791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6396,curation_candidate,14802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6397,curation_candidate,14803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6398,curation_candidate,14804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6399,curation_candidate,14806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6400,curation_candidate,14807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6401,curation_candidate,14819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6402,curation_candidate,14824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6403,curation_candidate,14833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6404,curation_candidate,14834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6405,curation_candidate,14848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6406,curation_candidate,14850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6407,curation_candidate,14857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6408,curation_candidate,14858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6409,curation_candidate,14860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6410,curation_candidate,14862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6411,curation_candidate,14864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6412,curation_candidate,14868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6413,curation_candidate,14869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6414,curation_candidate,14877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6415,curation_candidate,14889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6416,curation_candidate,14891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6417,curation_candidate,14893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6418,curation_candidate,14901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6419,curation_candidate,14903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6420,curation_candidate,14904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6421,curation_candidate,14906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6422,curation_candidate,14928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6423,curation_candidate,14938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6424,curation_candidate,14940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6425,curation_candidate,14941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6426,curation_candidate,14945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6427,curation_candidate,14949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6428,curation_candidate,14950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6429,curation_candidate,14952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6430,curation_candidate,15103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6431,curation_candidate,15133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6432,curation_candidate,15186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6433,curation_candidate,15187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6434,curation_candidate,15188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6435,curation_candidate,15191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6436,curation_candidate,15195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6437,curation_candidate,15201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6438,curation_candidate,15205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6439,curation_candidate,15206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6440,curation_candidate,15210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6441,curation_candidate,15213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6442,curation_candidate,15216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6443,curation_candidate,15218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6444,curation_candidate,15631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6445,curation_candidate,15635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6446,curation_candidate,15636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6447,curation_candidate,15637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6448,curation_candidate,15639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6449,curation_candidate,15647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6450,curation_candidate,15651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6451,curation_candidate,15652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6452,curation_candidate,15653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6453,curation_candidate,15659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6454,curation_candidate,15663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6455,curation_candidate,15665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6456,curation_candidate,15666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6457,curation_candidate,15670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6458,curation_candidate,15675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6459,curation_candidate,15686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6460,curation_candidate,15694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6461,curation_candidate,15695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6462,curation_candidate,15696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6463,curation_candidate,15697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6464,curation_candidate,15699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6465,curation_candidate,15716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6466,curation_candidate,10367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6467,curation_candidate,10574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6468,curation_candidate,10783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6469,curation_candidate,10791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6470,curation_candidate,10855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6471,curation_candidate,11004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6472,curation_candidate,11011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6473,curation_candidate,11017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
6474,curation_candidate,11018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6475,curation_candidate,11117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6476,curation_candidate,11118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6477,curation_candidate,11562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6478,curation_candidate,11570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6479,curation_candidate,11574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6480,curation_candidate,11575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6481,curation_candidate,11576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6482,curation_candidate,11585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
6483,curation_candidate,11587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6484,curation_candidate,11589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6485,curation_candidate,11593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6486,curation_candidate,11594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6487,curation_candidate,11595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6488,curation_candidate,11596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
6489,curation_candidate,11603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6490,curation_candidate,14954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6491,curation_candidate,14956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6492,curation_candidate,14957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6493,curation_candidate,14962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6494,curation_candidate,14966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6495,curation_candidate,14969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6496,curation_candidate,14970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6497,curation_candidate,14971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6498,curation_candidate,14974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6499,curation_candidate,14976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6500,curation_candidate,14978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6501,curation_candidate,14986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6502,curation_candidate,14992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6503,curation_candidate,14998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6504,curation_candidate,15000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6505,curation_candidate,15002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6506,curation_candidate,15004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6507,curation_candidate,15005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6508,curation_candidate,15006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6509,curation_candidate,15010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6510,curation_candidate,15011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6511,curation_candidate,15012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6512,curation_candidate,15015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6513,curation_candidate,15016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6514,curation_candidate,15020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6515,curation_candidate,15022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6516,curation_candidate,15039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6517,curation_candidate,15041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6518,curation_candidate,15042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6519,curation_candidate,15045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6520,curation_candidate,15048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6521,curation_candidate,15049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6522,curation_candidate,15056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6523,curation_candidate,15060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6524,curation_candidate,15061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6525,curation_candidate,15062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6526,curation_candidate,15074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6527,curation_candidate,15078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6528,curation_candidate,15083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6529,curation_candidate,15084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6530,curation_candidate,15086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6531,curation_candidate,15097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6532,curation_candidate,15223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6533,curation_candidate,15225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6534,curation_candidate,15227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6535,curation_candidate,15230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6536,curation_candidate,15231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6537,curation_candidate,15733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6538,curation_candidate,15741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6539,curation_candidate,15745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6540,curation_candidate,15767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6541,curation_candidate,15770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6542,curation_candidate,15772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6543,curation_candidate,15773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6544,curation_candidate,15787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6545,curation_candidate,15790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6546,curation_candidate,15794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6547,curation_candidate,15797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6548,curation_candidate,15799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6549,curation_candidate,15806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6550,curation_candidate,15808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6551,curation_candidate,15811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6552,curation_candidate,15813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6553,curation_candidate,15816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6554,curation_candidate,15817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6555,curation_candidate,15820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6556,curation_candidate,15824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6557,curation_candidate,15825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6558,curation_candidate,15830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6559,curation_candidate,15833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6560,curation_candidate,15840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6561,curation_candidate,15842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6562,curation_candidate,15845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6563,curation_candidate,15853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6564,curation_candidate,15858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6565,curation_candidate,15863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6566,curation_candidate,15865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6567,curation_candidate,15866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6568,curation_candidate,15868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
6569,curation_candidate,15877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6570,curation_candidate,15885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6571,curation_candidate,15887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6572,curation_candidate,15888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6573,curation_candidate,15893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6574,curation_candidate,15895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6575,curation_candidate,15911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6576,curation_candidate,15924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6577,curation_candidate,15930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6578,curation_candidate,15945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6579,curation_candidate,15947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6580,curation_candidate,10580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6581,curation_candidate,10581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6582,curation_candidate,10798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6583,curation_candidate,10812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6584,curation_candidate,10856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6585,curation_candidate,10921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6586,curation_candidate,11024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6587,curation_candidate,11026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6588,curation_candidate,11029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6589,curation_candidate,11030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6590,curation_candidate,11607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6591,curation_candidate,11608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6592,curation_candidate,11610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6593,curation_candidate,11614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6594,curation_candidate,11620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
6595,curation_candidate,11623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6596,curation_candidate,11627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6597,curation_candidate,11629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6598,curation_candidate,11636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6599,curation_candidate,11638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6600,curation_candidate,11762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6601,curation_candidate,15093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6602,curation_candidate,15232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6603,curation_candidate,15233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6604,curation_candidate,15234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6605,curation_candidate,15948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6606,curation_candidate,15952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6607,curation_candidate,15954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6608,curation_candidate,15956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6609,curation_candidate,15958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6610,curation_candidate,15960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6611,curation_candidate,15961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6612,curation_candidate,15965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6613,curation_candidate,15968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6614,curation_candidate,15970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6615,curation_candidate,15975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6616,curation_candidate,15978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6617,curation_candidate,15979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6618,curation_candidate,15982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6619,curation_candidate,15983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6620,curation_candidate,15988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6621,curation_candidate,15994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6622,curation_candidate,15997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6623,curation_candidate,16009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6624,curation_candidate,16015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6625,curation_candidate,16027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6626,curation_candidate,16036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6627,curation_candidate,16038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6628,curation_candidate,16040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6629,curation_candidate,16046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6630,curation_candidate,16061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6631,curation_candidate,16072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
6632,curation_candidate,16074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6633,curation_candidate,10536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6634,curation_candidate,10590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6635,curation_candidate,10596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6636,curation_candidate,10815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6637,curation_candidate,10818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6638,curation_candidate,10879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6639,curation_candidate,10924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6640,curation_candidate,11036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6641,curation_candidate,11040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6642,curation_candidate,11642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6643,curation_candidate,11644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6644,curation_candidate,11645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6645,curation_candidate,11646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6646,curation_candidate,11648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6647,curation_candidate,11653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6648,curation_candidate,11654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6649,curation_candidate,11656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6650,curation_candidate,11670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6651,curation_candidate,11671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6652,curation_candidate,15136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
6653,curation_candidate,16079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6654,curation_candidate,16082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6655,curation_candidate,16083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6656,curation_candidate,16085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6657,curation_candidate,16088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6658,curation_candidate,16134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6659,curation_candidate,16136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6660,curation_candidate,16140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6661,curation_candidate,16155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6662,curation_candidate,16160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6663,curation_candidate,16164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6664,curation_candidate,10905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6665,curation_candidate,10926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6666,curation_candidate,11674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6667,curation_candidate,11681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
6668,curation_candidate,11687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6669,curation_candidate,11691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6670,curation_candidate,15098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6671,curation_candidate,15244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6672,curation_candidate,15250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6673,curation_candidate,15251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6674,curation_candidate,15254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6675,curation_candidate,15256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6676,curation_candidate,15258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6677,curation_candidate,16176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6678,curation_candidate,16185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6679,curation_candidate,16187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6680,curation_candidate,16192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6681,curation_candidate,16200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6682,curation_candidate,16203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6683,curation_candidate,16206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6684,curation_candidate,11049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6685,curation_candidate,11696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6686,curation_candidate,11700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6687,curation_candidate,15261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6688,curation_candidate,15263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6689,curation_candidate,15267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6690,curation_candidate,15268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6691,curation_candidate,15270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6692,curation_candidate,16236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6693,curation_candidate,16240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6694,curation_candidate,16245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6695,curation_candidate,11710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6696,curation_candidate,15275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6697,curation_candidate,15276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6698,curation_candidate,15279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6699,curation_candidate,16264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6700,curation_candidate,16269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: computational source lacks concrete off-target evidence,2026-06-02T15:59:55+00:00
6701,curation_candidate,16272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6702,curation_candidate,16274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6703,curation_candidate,16278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6704,curation_candidate,10910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6705,curation_candidate,15095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6706,curation_candidate,15285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6707,curation_candidate,15289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6708,curation_candidate,15290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6709,curation_candidate,15292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6710,curation_candidate,16280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
6711,curation_candidate,16295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6712,curation_candidate,16302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6713,curation_candidate,15096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6714,curation_candidate,15295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6715,curation_candidate,15298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6716,curation_candidate,16314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6717,curation_candidate,11072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6718,curation_candidate,15301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
6719,curation_candidate,16321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6720,curation_candidate,10886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location is discussion-only generic off-target support,2026-06-02T15:59:55+00:00
6721,curation_candidate,11733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: methods source location is not an off-target assay result,2026-06-02T15:59:55+00:00
6722,curation_candidate,11750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6723,curation_candidate,11756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
6724,curation_candidate,10336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6725,curation_candidate,10339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6726,curation_candidate,10390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6727,curation_candidate,10394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6728,curation_candidate,10395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6729,curation_candidate,10451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6730,curation_candidate,10455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6731,curation_candidate,10457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6732,curation_candidate,10458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6733,curation_candidate,10462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6734,curation_candidate,10464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6735,curation_candidate,10465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6736,curation_candidate,10467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6737,curation_candidate,10469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6738,curation_candidate,10470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6739,curation_candidate,10471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6740,curation_candidate,10472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6741,curation_candidate,10477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6742,curation_candidate,10480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6743,curation_candidate,10485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6744,curation_candidate,10486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6745,curation_candidate,10487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6746,curation_candidate,10489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
6747,curation_candidate,10490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6748,curation_candidate,10492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6749,curation_candidate,10498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6750,curation_candidate,10502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6751,curation_candidate,10514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6752,curation_candidate,10522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6753,curation_candidate,10542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6754,curation_candidate,10546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6755,curation_candidate,10613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6756,curation_candidate,10617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6757,curation_candidate,10624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6758,curation_candidate,10625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6759,curation_candidate,10629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6760,curation_candidate,10630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6761,curation_candidate,10638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6762,curation_candidate,10640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6763,curation_candidate,10643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6764,curation_candidate,10656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6765,curation_candidate,10839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6766,curation_candidate,10840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6767,curation_candidate,10845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6768,curation_candidate,10847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6769,curation_candidate,10848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6770,curation_candidate,10849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6771,curation_candidate,10850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6772,curation_candidate,10866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6773,curation_candidate,10868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6774,curation_candidate,10934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6775,curation_candidate,11088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6776,curation_candidate,11093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6777,curation_candidate,11139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6778,curation_candidate,11140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6779,curation_candidate,11141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6780,curation_candidate,11142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6781,curation_candidate,11143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6782,curation_candidate,11145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6783,curation_candidate,11147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
6784,curation_candidate,11149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6785,curation_candidate,11152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6786,curation_candidate,11154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6787,curation_candidate,11157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6788,curation_candidate,11160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6789,curation_candidate,11163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6790,curation_candidate,11167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6791,curation_candidate,11168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6792,curation_candidate,11169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6793,curation_candidate,11170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6794,curation_candidate,11172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6795,curation_candidate,11178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6796,curation_candidate,11183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6797,curation_candidate,11196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6798,curation_candidate,11201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6799,curation_candidate,11207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6800,curation_candidate,11210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6801,curation_candidate,11211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6802,curation_candidate,11212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6803,curation_candidate,11218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6804,curation_candidate,11224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6805,curation_candidate,11225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6806,curation_candidate,11226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6807,curation_candidate,11228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6808,curation_candidate,11230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6809,curation_candidate,11231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6810,curation_candidate,11234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6811,curation_candidate,11236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6812,curation_candidate,11237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6813,curation_candidate,11239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6814,curation_candidate,11240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6815,curation_candidate,11242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6816,curation_candidate,11244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6817,curation_candidate,11245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6818,curation_candidate,11246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6819,curation_candidate,11248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6820,curation_candidate,11253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6821,curation_candidate,11765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6822,curation_candidate,11766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6823,curation_candidate,11767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6824,curation_candidate,11768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6825,curation_candidate,11770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6826,curation_candidate,11771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6827,curation_candidate,11775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6828,curation_candidate,11776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6829,curation_candidate,11777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6830,curation_candidate,11780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6831,curation_candidate,11783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6832,curation_candidate,11785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6833,curation_candidate,11786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6834,curation_candidate,11789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6835,curation_candidate,11795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6836,curation_candidate,11798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6837,curation_candidate,11802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6838,curation_candidate,11823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6839,curation_candidate,11826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
6840,curation_candidate,11829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6841,curation_candidate,11835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6842,curation_candidate,11836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6843,curation_candidate,11837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6844,curation_candidate,11839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6845,curation_candidate,11841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6846,curation_candidate,11842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6847,curation_candidate,11843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6848,curation_candidate,11853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6849,curation_candidate,11855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6850,curation_candidate,11856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6851,curation_candidate,11857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6852,curation_candidate,11858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6853,curation_candidate,11859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6854,curation_candidate,11860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6855,curation_candidate,11861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
6856,curation_candidate,11863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6857,curation_candidate,11865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6858,curation_candidate,11867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6859,curation_candidate,11870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6860,curation_candidate,11875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6861,curation_candidate,11876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6862,curation_candidate,11879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6863,curation_candidate,11880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6864,curation_candidate,11881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6865,curation_candidate,11883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6866,curation_candidate,11886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6867,curation_candidate,11887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6868,curation_candidate,11888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6869,curation_candidate,11902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6870,curation_candidate,11904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6871,curation_candidate,11905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6872,curation_candidate,11908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6873,curation_candidate,11909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6874,curation_candidate,11911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6875,curation_candidate,11912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6876,curation_candidate,11919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6877,curation_candidate,11926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6878,curation_candidate,11927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6879,curation_candidate,11929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6880,curation_candidate,11932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6881,curation_candidate,11933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6882,curation_candidate,11935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6883,curation_candidate,11936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6884,curation_candidate,11938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6885,curation_candidate,11939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6886,curation_candidate,11941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6887,curation_candidate,11943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6888,curation_candidate,11946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6889,curation_candidate,11951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6890,curation_candidate,11954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6891,curation_candidate,11955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6892,curation_candidate,11956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6893,curation_candidate,11964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6894,curation_candidate,11968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6895,curation_candidate,11970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6896,curation_candidate,11971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6897,curation_candidate,11972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6898,curation_candidate,11977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6899,curation_candidate,11978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6900,curation_candidate,11980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6901,curation_candidate,11987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6902,curation_candidate,11992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6903,curation_candidate,11993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6904,curation_candidate,11994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6905,curation_candidate,11998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6906,curation_candidate,11999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6907,curation_candidate,12001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6908,curation_candidate,12003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6909,curation_candidate,12005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6910,curation_candidate,12010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6911,curation_candidate,12011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6912,curation_candidate,12012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6913,curation_candidate,12017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6914,curation_candidate,12025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6915,curation_candidate,12027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6916,curation_candidate,12029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6917,curation_candidate,12030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6918,curation_candidate,12031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6919,curation_candidate,12032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6920,curation_candidate,12033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6921,curation_candidate,12035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6922,curation_candidate,12036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6923,curation_candidate,12039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6924,curation_candidate,12040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6925,curation_candidate,12048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6926,curation_candidate,12050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6927,curation_candidate,12055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6928,curation_candidate,12068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6929,curation_candidate,12070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6930,curation_candidate,12071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6931,curation_candidate,12073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6932,curation_candidate,12074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6933,curation_candidate,12078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6934,curation_candidate,12081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6935,curation_candidate,12082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6936,curation_candidate,12088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6937,curation_candidate,12093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6938,curation_candidate,12095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6939,curation_candidate,12098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6940,curation_candidate,12100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6941,curation_candidate,12101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6942,curation_candidate,12102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6943,curation_candidate,12108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6944,curation_candidate,12114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6945,curation_candidate,12118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6946,curation_candidate,12120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6947,curation_candidate,12123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6948,curation_candidate,12124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6949,curation_candidate,12126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6950,curation_candidate,12127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6951,curation_candidate,12128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6952,curation_candidate,12129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6953,curation_candidate,12132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6954,curation_candidate,12134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6955,curation_candidate,12137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6956,curation_candidate,12140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6957,curation_candidate,12145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6958,curation_candidate,12146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6959,curation_candidate,12147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6960,curation_candidate,12148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
6961,curation_candidate,12150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6962,curation_candidate,12154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6963,curation_candidate,12155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6964,curation_candidate,12156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6965,curation_candidate,12157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
6966,curation_candidate,12159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6967,curation_candidate,12161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6968,curation_candidate,12162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6969,curation_candidate,12168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6970,curation_candidate,12176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6971,curation_candidate,12177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6972,curation_candidate,12179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6973,curation_candidate,12180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6974,curation_candidate,12183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6975,curation_candidate,12184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6976,curation_candidate,12185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
6977,curation_candidate,12186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6978,curation_candidate,12187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6979,curation_candidate,12188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6980,curation_candidate,12189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6981,curation_candidate,12190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6982,curation_candidate,12208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6983,curation_candidate,12209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6984,curation_candidate,12211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6985,curation_candidate,12212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6986,curation_candidate,12213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6987,curation_candidate,12218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6988,curation_candidate,12219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6989,curation_candidate,12221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6990,curation_candidate,12222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6991,curation_candidate,12234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6992,curation_candidate,12239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6993,curation_candidate,12240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6994,curation_candidate,12241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6995,curation_candidate,12247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
6996,curation_candidate,12248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6997,curation_candidate,12251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6998,curation_candidate,12253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
6999,curation_candidate,12256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7000,curation_candidate,12264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7001,curation_candidate,12265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7002,curation_candidate,12266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7003,curation_candidate,12277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7004,curation_candidate,12282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7005,curation_candidate,12286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7006,curation_candidate,12288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7007,curation_candidate,12291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7008,curation_candidate,12293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7009,curation_candidate,12298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7010,curation_candidate,12301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7011,curation_candidate,12303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7012,curation_candidate,12304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7013,curation_candidate,12305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7014,curation_candidate,12306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7015,curation_candidate,12310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7016,curation_candidate,12312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7017,curation_candidate,12313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7018,curation_candidate,12315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7019,curation_candidate,12318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7020,curation_candidate,12319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7021,curation_candidate,12324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7022,curation_candidate,12327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7023,curation_candidate,12328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7024,curation_candidate,12331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7025,curation_candidate,12337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7026,curation_candidate,12339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7027,curation_candidate,12340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7028,curation_candidate,12341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7029,curation_candidate,12362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7030,curation_candidate,12367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7031,curation_candidate,12368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7032,curation_candidate,12376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7033,curation_candidate,12378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7034,curation_candidate,12380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7035,curation_candidate,12392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7036,curation_candidate,12394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7037,curation_candidate,12395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7038,curation_candidate,12401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7039,curation_candidate,12402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7040,curation_candidate,12404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7041,curation_candidate,12405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7042,curation_candidate,12410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7043,curation_candidate,12415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7044,curation_candidate,12427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7045,curation_candidate,12428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7046,curation_candidate,12432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7047,curation_candidate,12435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7048,curation_candidate,12442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7049,curation_candidate,12443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7050,curation_candidate,12447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7051,curation_candidate,12448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7052,curation_candidate,12458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7053,curation_candidate,12466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7054,curation_candidate,12467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7055,curation_candidate,12469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7056,curation_candidate,12473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7057,curation_candidate,12475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7058,curation_candidate,12477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7059,curation_candidate,12482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7060,curation_candidate,12487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7061,curation_candidate,12494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7062,curation_candidate,12495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7063,curation_candidate,12497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7064,curation_candidate,12498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7065,curation_candidate,12500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7066,curation_candidate,12501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7067,curation_candidate,12502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7068,curation_candidate,12503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7069,curation_candidate,12504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7070,curation_candidate,12505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7071,curation_candidate,12507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7072,curation_candidate,12512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7073,curation_candidate,12523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7074,curation_candidate,12530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7075,curation_candidate,12531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7076,curation_candidate,12534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7077,curation_candidate,12538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7078,curation_candidate,12539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7079,curation_candidate,12541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7080,curation_candidate,12544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7081,curation_candidate,12545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7082,curation_candidate,12548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7083,curation_candidate,12550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7084,curation_candidate,12563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7085,curation_candidate,12564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7086,curation_candidate,12565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7087,curation_candidate,12567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7088,curation_candidate,12576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7089,curation_candidate,12579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7090,curation_candidate,12583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7091,curation_candidate,12585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7092,curation_candidate,12587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7093,curation_candidate,12594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7094,curation_candidate,12601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7095,curation_candidate,12602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7096,curation_candidate,12603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7097,curation_candidate,12606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7098,curation_candidate,12607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7099,curation_candidate,12619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7100,curation_candidate,12623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7101,curation_candidate,12627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7102,curation_candidate,12636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7103,curation_candidate,12642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7104,curation_candidate,12644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7105,curation_candidate,12646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7106,curation_candidate,12652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7107,curation_candidate,12655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7108,curation_candidate,12663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7109,curation_candidate,12665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7110,curation_candidate,12666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7111,curation_candidate,12670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7112,curation_candidate,12673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7113,curation_candidate,12676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7114,curation_candidate,12680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7115,curation_candidate,12697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7116,curation_candidate,12698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7117,curation_candidate,12704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7118,curation_candidate,12714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7119,curation_candidate,12715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7120,curation_candidate,12717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7121,curation_candidate,12718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7122,curation_candidate,12720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7123,curation_candidate,12721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7124,curation_candidate,12723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7125,curation_candidate,12731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7126,curation_candidate,12733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7127,curation_candidate,12734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7128,curation_candidate,12739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7129,curation_candidate,12744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7130,curation_candidate,12748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7131,curation_candidate,12749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7132,curation_candidate,12750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7133,curation_candidate,12752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7134,curation_candidate,12754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7135,curation_candidate,12756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7136,curation_candidate,12758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7137,curation_candidate,12762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7138,curation_candidate,12764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7139,curation_candidate,12765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7140,curation_candidate,12772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7141,curation_candidate,12778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7142,curation_candidate,12782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7143,curation_candidate,12804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7144,curation_candidate,12807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7145,curation_candidate,12809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7146,curation_candidate,12811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7147,curation_candidate,12812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7148,curation_candidate,12814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7149,curation_candidate,12817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7150,curation_candidate,12821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7151,curation_candidate,12822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7152,curation_candidate,12824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7153,curation_candidate,12825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7154,curation_candidate,12826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7155,curation_candidate,12829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7156,curation_candidate,12831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7157,curation_candidate,12833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7158,curation_candidate,12835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7159,curation_candidate,12837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7160,curation_candidate,12840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7161,curation_candidate,12850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7162,curation_candidate,12853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7163,curation_candidate,12856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7164,curation_candidate,12859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7165,curation_candidate,12860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7166,curation_candidate,12862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7167,curation_candidate,12863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7168,curation_candidate,12866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7169,curation_candidate,12870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7170,curation_candidate,12872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7171,curation_candidate,12873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7172,curation_candidate,12876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7173,curation_candidate,12878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7174,curation_candidate,12881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
7175,curation_candidate,12887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7176,curation_candidate,12896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7177,curation_candidate,12898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7178,curation_candidate,12899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7179,curation_candidate,12909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7180,curation_candidate,12911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7181,curation_candidate,12913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7182,curation_candidate,12914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7183,curation_candidate,12917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7184,curation_candidate,12919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7185,curation_candidate,12920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7186,curation_candidate,12927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7187,curation_candidate,12929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7188,curation_candidate,12930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7189,curation_candidate,12931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7190,curation_candidate,12935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7191,curation_candidate,12936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7192,curation_candidate,12938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7193,curation_candidate,12939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7194,curation_candidate,12941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7195,curation_candidate,12943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7196,curation_candidate,12944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7197,curation_candidate,12947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7198,curation_candidate,12951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7199,curation_candidate,12952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7200,curation_candidate,12955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7201,curation_candidate,12957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7202,curation_candidate,12958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7203,curation_candidate,12962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7204,curation_candidate,12963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7205,curation_candidate,12967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7206,curation_candidate,12970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
7207,curation_candidate,12973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7208,curation_candidate,12975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7209,curation_candidate,12979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7210,curation_candidate,12981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7211,curation_candidate,12983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7212,curation_candidate,12986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7213,curation_candidate,12988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7214,curation_candidate,12995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7215,curation_candidate,12999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7216,curation_candidate,13000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7217,curation_candidate,13002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7218,curation_candidate,13004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7219,curation_candidate,13007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7220,curation_candidate,13009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7221,curation_candidate,13010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7222,curation_candidate,13012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7223,curation_candidate,13013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7224,curation_candidate,13014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7225,curation_candidate,13015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7226,curation_candidate,13016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7227,curation_candidate,13017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7228,curation_candidate,13018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7229,curation_candidate,13020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7230,curation_candidate,13023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7231,curation_candidate,13026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7232,curation_candidate,13027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7233,curation_candidate,13030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7234,curation_candidate,13036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7235,curation_candidate,13038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7236,curation_candidate,13042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7237,curation_candidate,13045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7238,curation_candidate,13046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7239,curation_candidate,13052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7240,curation_candidate,13053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7241,curation_candidate,13061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7242,curation_candidate,13064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7243,curation_candidate,13066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7244,curation_candidate,13068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7245,curation_candidate,13070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7246,curation_candidate,13071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7247,curation_candidate,13074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7248,curation_candidate,13079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
7249,curation_candidate,13085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7250,curation_candidate,13091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7251,curation_candidate,13095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7252,curation_candidate,13104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7253,curation_candidate,15100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7254,curation_candidate,15141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7255,curation_candidate,15142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7256,curation_candidate,15143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7257,curation_candidate,15145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7258,curation_candidate,15304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7259,curation_candidate,15307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7260,curation_candidate,15308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7261,curation_candidate,15314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7262,curation_candidate,15318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7263,curation_candidate,15322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7264,curation_candidate,15323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7265,curation_candidate,15324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7266,curation_candidate,15331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7267,curation_candidate,15347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7268,curation_candidate,15348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7269,curation_candidate,15356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7270,curation_candidate,15358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7271,curation_candidate,15361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7272,curation_candidate,15362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
7273,curation_candidate,15363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7274,curation_candidate,15364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7275,curation_candidate,15377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7276,curation_candidate,15381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7277,curation_candidate,15383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7278,curation_candidate,15386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7279,curation_candidate,15776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7280,curation_candidate,15778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
7281,curation_candidate,15780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7282,curation_candidate,15782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7283,curation_candidate,15783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7284,curation_candidate,15784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7285,curation_candidate,15785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7286,curation_candidate,15786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7287,curation_candidate,10314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7288,curation_candidate,10321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7289,curation_candidate,10329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7290,curation_candidate,10355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7291,curation_candidate,10369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
7292,curation_candidate,10405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7293,curation_candidate,10407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7294,curation_candidate,10549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7295,curation_candidate,10552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7296,curation_candidate,10684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7297,curation_candidate,10697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7298,curation_candidate,10699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7299,curation_candidate,10712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7300,curation_candidate,10715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7301,curation_candidate,10718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7302,curation_candidate,10729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7303,curation_candidate,10735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7304,curation_candidate,10860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7305,curation_candidate,10870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7306,curation_candidate,10871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7307,curation_candidate,10875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7308,curation_candidate,10898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7309,curation_candidate,10918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7310,curation_candidate,10919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7311,curation_candidate,10937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7312,curation_candidate,10939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7313,curation_candidate,10946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7314,curation_candidate,10947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7315,curation_candidate,10948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7316,curation_candidate,10949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7317,curation_candidate,10951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7318,curation_candidate,10955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7319,curation_candidate,10957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7320,curation_candidate,10960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7321,curation_candidate,10965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7322,curation_candidate,10966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7323,curation_candidate,10971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7324,curation_candidate,11102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7325,curation_candidate,11105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7326,curation_candidate,11106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7327,curation_candidate,11276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7328,curation_candidate,11277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7329,curation_candidate,11281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7330,curation_candidate,11284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7331,curation_candidate,11285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7332,curation_candidate,11288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7333,curation_candidate,11290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7334,curation_candidate,11291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7335,curation_candidate,11297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7336,curation_candidate,11298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7337,curation_candidate,11307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7338,curation_candidate,11309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7339,curation_candidate,11313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7340,curation_candidate,11315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7341,curation_candidate,11320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7342,curation_candidate,11323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7343,curation_candidate,11330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7344,curation_candidate,11331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7345,curation_candidate,11333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7346,curation_candidate,11334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7347,curation_candidate,11343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7348,curation_candidate,11344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7349,curation_candidate,11355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7350,curation_candidate,11363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7351,curation_candidate,11366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7352,curation_candidate,11367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7353,curation_candidate,11368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7354,curation_candidate,11369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7355,curation_candidate,11374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7356,curation_candidate,11378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
7357,curation_candidate,11383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7358,curation_candidate,11387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7359,curation_candidate,11388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7360,curation_candidate,11389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7361,curation_candidate,11397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7362,curation_candidate,11398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7363,curation_candidate,11399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7364,curation_candidate,11404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7365,curation_candidate,11421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7366,curation_candidate,11425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7367,curation_candidate,11427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7368,curation_candidate,11430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7369,curation_candidate,11433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7370,curation_candidate,11437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7371,curation_candidate,11442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7372,curation_candidate,11444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7373,curation_candidate,11451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7374,curation_candidate,11454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7375,curation_candidate,11457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7376,curation_candidate,11459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
7377,curation_candidate,11461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7378,curation_candidate,11463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7379,curation_candidate,11468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7380,curation_candidate,11470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7381,curation_candidate,13140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7382,curation_candidate,13149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7383,curation_candidate,13170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7384,curation_candidate,13175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7385,curation_candidate,13189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7386,curation_candidate,13216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7387,curation_candidate,13231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7388,curation_candidate,13233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7389,curation_candidate,13259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7390,curation_candidate,13272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7391,curation_candidate,13289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7392,curation_candidate,13296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7393,curation_candidate,13300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7394,curation_candidate,13301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7395,curation_candidate,13304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7396,curation_candidate,13322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7397,curation_candidate,13323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7398,curation_candidate,13324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7399,curation_candidate,13327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7400,curation_candidate,13328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7401,curation_candidate,13331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7402,curation_candidate,13336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7403,curation_candidate,13342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7404,curation_candidate,13347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7405,curation_candidate,13353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7406,curation_candidate,13358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7407,curation_candidate,13359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7408,curation_candidate,13371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7409,curation_candidate,13385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7410,curation_candidate,13396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7411,curation_candidate,13397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7412,curation_candidate,13400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7413,curation_candidate,13401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7414,curation_candidate,13404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7415,curation_candidate,13413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7416,curation_candidate,13426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7417,curation_candidate,13429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7418,curation_candidate,13430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7419,curation_candidate,13433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7420,curation_candidate,13437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7421,curation_candidate,13446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7422,curation_candidate,13448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7423,curation_candidate,13449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7424,curation_candidate,13454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7425,curation_candidate,13462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7426,curation_candidate,13463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7427,curation_candidate,13466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7428,curation_candidate,13469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7429,curation_candidate,13478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7430,curation_candidate,13482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7431,curation_candidate,13487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7432,curation_candidate,13495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7433,curation_candidate,13497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7434,curation_candidate,13500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7435,curation_candidate,13501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7436,curation_candidate,13502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7437,curation_candidate,13503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T15:59:55+00:00
7438,curation_candidate,13507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7439,curation_candidate,13521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7440,curation_candidate,13528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7441,curation_candidate,13530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7442,curation_candidate,13535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7443,curation_candidate,13544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7444,curation_candidate,13545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7445,curation_candidate,13554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7446,curation_candidate,13560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7447,curation_candidate,13563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7448,curation_candidate,13564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7449,curation_candidate,13571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7450,curation_candidate,13574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7451,curation_candidate,13587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7452,curation_candidate,13591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7453,curation_candidate,13594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7454,curation_candidate,13597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7455,curation_candidate,13599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7456,curation_candidate,13600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7457,curation_candidate,13601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7458,curation_candidate,13602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7459,curation_candidate,13603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7460,curation_candidate,13604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7461,curation_candidate,13605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7462,curation_candidate,13607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7463,curation_candidate,13608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7464,curation_candidate,13610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7465,curation_candidate,13613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7466,curation_candidate,13625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7467,curation_candidate,13632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7468,curation_candidate,13636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7469,curation_candidate,13638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7470,curation_candidate,13639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7471,curation_candidate,13641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7472,curation_candidate,13644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7473,curation_candidate,13657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7474,curation_candidate,13662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7475,curation_candidate,13668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7476,curation_candidate,13672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7477,curation_candidate,13677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7478,curation_candidate,13680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7479,curation_candidate,13683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7480,curation_candidate,13689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7481,curation_candidate,13690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7482,curation_candidate,13693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7483,curation_candidate,13694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7484,curation_candidate,13700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7485,curation_candidate,13702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7486,curation_candidate,13712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T15:59:55+00:00
7487,curation_candidate,13721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not support specific off-target evidence,2026-06-02T15:59:55+00:00
7488,curation_candidate,10461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7489,curation_candidate,10504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7490,curation_candidate,10506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7491,curation_candidate,10543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7492,curation_candidate,10647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7493,curation_candidate,10651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7494,curation_candidate,10652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7495,curation_candidate,10835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7496,curation_candidate,11156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7497,curation_candidate,11197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7498,curation_candidate,11199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7499,curation_candidate,11793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7500,curation_candidate,11797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7501,curation_candidate,11890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7502,curation_candidate,11961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7503,curation_candidate,12059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7504,curation_candidate,12107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7505,curation_candidate,12144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7506,curation_candidate,12153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7507,curation_candidate,12224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7508,curation_candidate,12227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7509,curation_candidate,12229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7510,curation_candidate,12243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7511,curation_candidate,12322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7512,curation_candidate,12345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7513,curation_candidate,12359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7514,curation_candidate,12365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7515,curation_candidate,12418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7516,curation_candidate,12422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7517,curation_candidate,12423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7518,curation_candidate,12438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7519,curation_candidate,12451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7520,curation_candidate,12536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7521,curation_candidate,12554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7522,curation_candidate,12555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7523,curation_candidate,12557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7524,curation_candidate,12571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7525,curation_candidate,12600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7526,curation_candidate,12622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7527,curation_candidate,12631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7528,curation_candidate,12669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7529,curation_candidate,12688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7530,curation_candidate,12713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7531,curation_candidate,12726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7532,curation_candidate,12728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7533,curation_candidate,12730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7534,curation_candidate,12788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7535,curation_candidate,12792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7536,curation_candidate,12795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7537,curation_candidate,12828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7538,curation_candidate,12902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7539,curation_candidate,12905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7540,curation_candidate,12906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7541,curation_candidate,12908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7542,curation_candidate,12915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7543,curation_candidate,12925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7544,curation_candidate,12940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7545,curation_candidate,12990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7546,curation_candidate,13043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7547,curation_candidate,13055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7548,curation_candidate,13073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7549,curation_candidate,13086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7550,curation_candidate,15337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7551,curation_candidate,15376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7552,curation_candidate,10403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7553,curation_candidate,10453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7554,curation_candidate,10523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7555,curation_candidate,10670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7556,curation_candidate,10676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7557,curation_candidate,10677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7558,curation_candidate,10693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7559,curation_candidate,10702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7560,curation_candidate,10714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7561,curation_candidate,10732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7562,curation_candidate,11258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7563,curation_candidate,11294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7564,curation_candidate,11303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7565,curation_candidate,11351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7566,curation_candidate,11409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7567,curation_candidate,11413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7568,curation_candidate,13125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7569,curation_candidate,13150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7570,curation_candidate,13179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7571,curation_candidate,13184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7572,curation_candidate,13185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7573,curation_candidate,13188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7574,curation_candidate,13208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7575,curation_candidate,13222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7576,curation_candidate,13229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7577,curation_candidate,13242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7578,curation_candidate,13243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7579,curation_candidate,13247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7580,curation_candidate,13275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7581,curation_candidate,13279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7582,curation_candidate,13291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7583,curation_candidate,13308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7584,curation_candidate,13338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7585,curation_candidate,13352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7586,curation_candidate,13360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7587,curation_candidate,13384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7588,curation_candidate,13386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7589,curation_candidate,13387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7590,curation_candidate,13407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7591,curation_candidate,13442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7592,curation_candidate,13443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7593,curation_candidate,13461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7594,curation_candidate,13490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7595,curation_candidate,13510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7596,curation_candidate,13539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7597,curation_candidate,13565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7598,curation_candidate,13582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7599,curation_candidate,13652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7600,curation_candidate,13656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7601,curation_candidate,13674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7602,curation_candidate,13734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7603,curation_candidate,13738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7604,curation_candidate,13740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7605,curation_candidate,13743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7606,curation_candidate,13762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7607,curation_candidate,13764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7608,curation_candidate,13806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7609,curation_candidate,13822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7610,curation_candidate,13825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7611,curation_candidate,13829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7612,curation_candidate,13846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7613,curation_candidate,13889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7614,curation_candidate,13913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7615,curation_candidate,13928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7616,curation_candidate,13947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7617,curation_candidate,14016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7618,curation_candidate,14044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7619,curation_candidate,14063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7620,curation_candidate,14121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7621,curation_candidate,14179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7622,curation_candidate,14183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7623,curation_candidate,14191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7624,curation_candidate,14199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7625,curation_candidate,14237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7626,curation_candidate,14243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7627,curation_candidate,14315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7628,curation_candidate,14331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7629,curation_candidate,14341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7630,curation_candidate,14355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7631,curation_candidate,14393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7632,curation_candidate,14399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7633,curation_candidate,15151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7634,curation_candidate,15160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7635,curation_candidate,15408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7636,curation_candidate,15414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7637,curation_candidate,15415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7638,curation_candidate,15449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7639,curation_candidate,15453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7640,curation_candidate,15459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7641,curation_candidate,15475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7642,curation_candidate,15504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7643,curation_candidate,15528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7644,curation_candidate,15557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7645,curation_candidate,15591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7646,curation_candidate,15605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7647,curation_candidate,15612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7648,curation_candidate,15623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7649,curation_candidate,15625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7650,curation_candidate,10439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7651,curation_candidate,10565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7652,curation_candidate,10766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7653,curation_candidate,10775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7654,curation_candidate,10997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7655,curation_candidate,11490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7656,curation_candidate,11506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7657,curation_candidate,11540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7658,curation_candidate,14451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7659,curation_candidate,14461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7660,curation_candidate,14467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7661,curation_candidate,14474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7662,curation_candidate,14486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7663,curation_candidate,14555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7664,curation_candidate,14574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7665,curation_candidate,14579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7666,curation_candidate,14582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7667,curation_candidate,14619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7668,curation_candidate,14640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7669,curation_candidate,14643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7670,curation_candidate,14645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7671,curation_candidate,14668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7672,curation_candidate,14692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7673,curation_candidate,14766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7674,curation_candidate,14781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7675,curation_candidate,14867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7676,curation_candidate,14892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7677,curation_candidate,14894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7678,curation_candidate,14896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7679,curation_candidate,14918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7680,curation_candidate,14932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7681,curation_candidate,14951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7682,curation_candidate,15212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7683,curation_candidate,15642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7684,curation_candidate,15649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7685,curation_candidate,15698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7686,curation_candidate,15714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7687,curation_candidate,15719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7688,curation_candidate,10530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7689,curation_candidate,10784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7690,curation_candidate,10787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7691,curation_candidate,10789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7692,curation_candidate,10792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7693,curation_candidate,11563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7694,curation_candidate,11583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7695,curation_candidate,11591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7696,curation_candidate,11597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7697,curation_candidate,14958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7698,curation_candidate,14960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7699,curation_candidate,14965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7700,curation_candidate,14977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7701,curation_candidate,14987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7702,curation_candidate,15001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7703,curation_candidate,15003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7704,curation_candidate,15013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7705,curation_candidate,15071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7706,curation_candidate,15073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7707,curation_candidate,15079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7708,curation_candidate,15106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7709,curation_candidate,15108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7710,curation_candidate,15111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7711,curation_candidate,15112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7712,curation_candidate,15731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7713,curation_candidate,15746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7714,curation_candidate,15751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7715,curation_candidate,15754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7716,curation_candidate,15795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7717,curation_candidate,15798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7718,curation_candidate,15802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7719,curation_candidate,15812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7720,curation_candidate,15821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7721,curation_candidate,15822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7722,curation_candidate,15841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7723,curation_candidate,15864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7724,curation_candidate,15871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7725,curation_candidate,15878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7726,curation_candidate,15880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7727,curation_candidate,15890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7728,curation_candidate,15900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7729,curation_candidate,15904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7730,curation_candidate,15918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7731,curation_candidate,10535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7732,curation_candidate,10578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7733,curation_candidate,10585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7734,curation_candidate,10800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7735,curation_candidate,10801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7736,curation_candidate,10806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7737,curation_candidate,10920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7738,curation_candidate,11609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7739,curation_candidate,11637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7740,curation_candidate,15949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7741,curation_candidate,16018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7742,curation_candidate,16028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7743,curation_candidate,16029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7744,curation_candidate,16041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7745,curation_candidate,16042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7746,curation_candidate,16043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7747,curation_candidate,16051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7748,curation_candidate,16068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7749,curation_candidate,10589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:55+00:00
7750,curation_candidate,10593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7751,curation_candidate,10816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7752,curation_candidate,10819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7753,curation_candidate,10825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7754,curation_candidate,11649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7755,curation_candidate,11659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7756,curation_candidate,15137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7757,curation_candidate,16086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7758,curation_candidate,16096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7759,curation_candidate,16119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7760,curation_candidate,16127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7761,curation_candidate,16130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7762,curation_candidate,16135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7763,curation_candidate,16138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7764,curation_candidate,16161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7765,curation_candidate,16166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7766,curation_candidate,10602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7767,curation_candidate,11131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7768,curation_candidate,11673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7769,curation_candidate,15140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7770,curation_candidate,16188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7771,curation_candidate,16198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7772,curation_candidate,16204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7773,curation_candidate,16205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7774,curation_candidate,16207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7775,curation_candidate,16214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7776,curation_candidate,11698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7777,curation_candidate,11704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7778,curation_candidate,16230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7779,curation_candidate,16239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7780,curation_candidate,16246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7781,curation_candidate,16247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7782,curation_candidate,11058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7783,curation_candidate,16279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7784,curation_candidate,16281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7785,curation_candidate,16303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7786,curation_candidate,16307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7787,curation_candidate,16313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7788,curation_candidate,11070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7789,curation_candidate,11136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7790,curation_candidate,15302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7791,curation_candidate,11749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7792,curation_candidate,10333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7793,curation_candidate,10386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7794,curation_candidate,10396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7795,curation_candidate,10397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7796,curation_candidate,10474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7797,curation_candidate,10476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7798,curation_candidate,10544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7799,curation_candidate,10620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7800,curation_candidate,10639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7801,curation_candidate,10654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7802,curation_candidate,10655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7803,curation_candidate,11155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7804,curation_candidate,11216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7805,curation_candidate,11220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7806,curation_candidate,11235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7807,curation_candidate,11796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7808,curation_candidate,11799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7809,curation_candidate,11827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7810,curation_candidate,11862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7811,curation_candidate,11864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7812,curation_candidate,11885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7813,curation_candidate,11896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7814,curation_candidate,11906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7815,curation_candidate,11921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7816,curation_candidate,11942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7817,curation_candidate,11962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7818,curation_candidate,11967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7819,curation_candidate,11969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7820,curation_candidate,11985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7821,curation_candidate,12041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7822,curation_candidate,12069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7823,curation_candidate,12072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7824,curation_candidate,12141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7825,curation_candidate,12163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7826,curation_candidate,12191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7827,curation_candidate,12257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7828,curation_candidate,12258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7829,curation_candidate,12259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7830,curation_candidate,12316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7831,curation_candidate,12332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7832,curation_candidate,12377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7833,curation_candidate,12400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7834,curation_candidate,12426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7835,curation_candidate,12433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7836,curation_candidate,12434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7837,curation_candidate,12454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7838,curation_candidate,12455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7839,curation_candidate,12474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7840,curation_candidate,12476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7841,curation_candidate,12481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7842,curation_candidate,12488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7843,curation_candidate,12499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7844,curation_candidate,12508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7845,curation_candidate,12524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7846,curation_candidate,12577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7847,curation_candidate,12592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7848,curation_candidate,12598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7849,curation_candidate,12656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7850,curation_candidate,12671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7851,curation_candidate,12716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7852,curation_candidate,12732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7853,curation_candidate,12757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7854,curation_candidate,12766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7855,curation_candidate,12783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7856,curation_candidate,12818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7857,curation_candidate,12854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7858,curation_candidate,12888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7859,curation_candidate,12918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7860,curation_candidate,12924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7861,curation_candidate,12949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7862,curation_candidate,12968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7863,curation_candidate,12978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7864,curation_candidate,12980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7865,curation_candidate,12984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7866,curation_candidate,12994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7867,curation_candidate,12998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7868,curation_candidate,13003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7869,curation_candidate,13019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7870,curation_candidate,13025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7871,curation_candidate,13103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7872,curation_candidate,13105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7873,curation_candidate,15325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7874,curation_candidate,15387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7875,curation_candidate,15777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7876,curation_candidate,10315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7877,curation_candidate,10316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7878,curation_candidate,10317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7879,curation_candidate,10326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7880,curation_candidate,10356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7881,curation_candidate,10379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7882,curation_candidate,10410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7883,curation_candidate,10553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7884,curation_candidate,10685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7885,curation_candidate,10707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7886,curation_candidate,10728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7887,curation_candidate,10888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7888,curation_candidate,10967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7889,curation_candidate,10972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7890,curation_candidate,11108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7891,curation_candidate,11278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7892,curation_candidate,11314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7893,curation_candidate,11373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7894,curation_candidate,11422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7895,curation_candidate,11432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7896,curation_candidate,11443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7897,curation_candidate,11464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7898,curation_candidate,13163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7899,curation_candidate,13226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7900,curation_candidate,13273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7901,curation_candidate,13282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7902,curation_candidate,13299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7903,curation_candidate,13341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7904,curation_candidate,13344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7905,curation_candidate,13409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7906,curation_candidate,13410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7907,curation_candidate,13427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7908,curation_candidate,13450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7909,curation_candidate,13451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7910,curation_candidate,13458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7911,curation_candidate,13465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7912,curation_candidate,13467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7913,curation_candidate,13523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7914,curation_candidate,13553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7915,curation_candidate,13584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7916,curation_candidate,13598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7917,curation_candidate,13606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7918,curation_candidate,13634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7919,curation_candidate,13640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7920,curation_candidate,13687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7921,curation_candidate,13691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7922,curation_candidate,13722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7923,curation_candidate,13731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7924,curation_candidate,13752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7925,curation_candidate,13758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7926,curation_candidate,13763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7927,curation_candidate,13790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7928,curation_candidate,13832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7929,curation_candidate,13834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7930,curation_candidate,13851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7931,curation_candidate,13864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7932,curation_candidate,13878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7933,curation_candidate,13881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7934,curation_candidate,13899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7935,curation_candidate,13936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7936,curation_candidate,13962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7937,curation_candidate,13979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7938,curation_candidate,14013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7939,curation_candidate,14023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7940,curation_candidate,14036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7941,curation_candidate,14048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7942,curation_candidate,14058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7943,curation_candidate,14068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7944,curation_candidate,14084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7945,curation_candidate,14125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7946,curation_candidate,14139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7947,curation_candidate,14147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7948,curation_candidate,14151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7949,curation_candidate,14152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7950,curation_candidate,14170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7951,curation_candidate,14196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7952,curation_candidate,14214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7953,curation_candidate,14222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7954,curation_candidate,14223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7955,curation_candidate,14224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7956,curation_candidate,14262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7957,curation_candidate,14291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7958,curation_candidate,14334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7959,curation_candidate,14365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7960,curation_candidate,14372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7961,curation_candidate,14386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7962,curation_candidate,14389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7963,curation_candidate,14407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7964,curation_candidate,14410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7965,curation_candidate,14421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7966,curation_candidate,14437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7967,curation_candidate,15152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7968,curation_candidate,15419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7969,curation_candidate,15476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7970,curation_candidate,15492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7971,curation_candidate,15531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7972,curation_candidate,15569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7973,curation_candidate,15575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7974,curation_candidate,15580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7975,curation_candidate,15594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
7976,curation_candidate,15599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7977,curation_candidate,15603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7978,curation_candidate,15613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7979,curation_candidate,15616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7980,curation_candidate,15620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7981,curation_candidate,15624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7982,curation_candidate,10767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7983,curation_candidate,10772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7984,curation_candidate,10776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:55+00:00
7985,curation_candidate,10999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7986,curation_candidate,11481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7987,curation_candidate,11482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7988,curation_candidate,11502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7989,curation_candidate,11539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7990,curation_candidate,11542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7991,curation_candidate,14479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
7992,curation_candidate,14500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
7993,curation_candidate,14514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7994,curation_candidate,14527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
7995,curation_candidate,14587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
7996,curation_candidate,14593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7997,curation_candidate,14615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
7998,curation_candidate,14634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
7999,curation_candidate,14641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8000,curation_candidate,14674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8001,curation_candidate,14681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8002,curation_candidate,14682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8003,curation_candidate,14698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8004,curation_candidate,14714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8005,curation_candidate,14716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8006,curation_candidate,14717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8007,curation_candidate,14719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8008,curation_candidate,14739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8009,curation_candidate,14761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8010,curation_candidate,14767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8011,curation_candidate,14795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8012,curation_candidate,14865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8013,curation_candidate,14890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8014,curation_candidate,14922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
8015,curation_candidate,14926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8016,curation_candidate,14927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8017,curation_candidate,14943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8018,curation_candidate,14946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
8019,curation_candidate,15662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8020,curation_candidate,15679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8021,curation_candidate,15681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8022,curation_candidate,15687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8023,curation_candidate,15691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8024,curation_candidate,15693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8025,curation_candidate,15712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8026,curation_candidate,15725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8027,curation_candidate,11561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8028,curation_candidate,14981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8029,curation_candidate,15053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
8030,curation_candidate,15058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8031,curation_candidate,15080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
8032,curation_candidate,15752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8033,curation_candidate,15753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8034,curation_candidate,15763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8035,curation_candidate,15801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8036,curation_candidate,15837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8037,curation_candidate,15849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8038,curation_candidate,15851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8039,curation_candidate,15861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8040,curation_candidate,15872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8041,curation_candidate,15892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8042,curation_candidate,15921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8043,curation_candidate,15923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8044,curation_candidate,15927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8045,curation_candidate,15931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8046,curation_candidate,10811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8047,curation_candidate,11023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8048,curation_candidate,11632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8049,curation_candidate,11633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8050,curation_candidate,15951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8051,curation_candidate,15964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8052,curation_candidate,15985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8053,curation_candidate,16007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8054,curation_candidate,16008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8055,curation_candidate,16030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8056,curation_candidate,10600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8057,curation_candidate,10880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
8058,curation_candidate,11643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8059,curation_candidate,11655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8060,curation_candidate,16099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8061,curation_candidate,16105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8062,curation_candidate,16111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8063,curation_candidate,16112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
8064,curation_candidate,16117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8065,curation_candidate,16139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8066,curation_candidate,16168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:55+00:00
8067,curation_candidate,16169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8068,curation_candidate,10606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8069,curation_candidate,10607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8070,curation_candidate,10612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:55+00:00
8071,curation_candidate,10622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8072,curation_candidate,10833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8073,curation_candidate,10834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8074,curation_candidate,11127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8075,curation_candidate,11678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8076,curation_candidate,11694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8077,curation_candidate,16180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8078,curation_candidate,16216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
8079,curation_candidate,16221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:55+00:00
8080,curation_candidate,16223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8081,curation_candidate,16224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8082,curation_candidate,16227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8083,curation_candidate,10928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8084,curation_candidate,11699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8085,curation_candidate,11057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8086,curation_candidate,15123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8087,curation_candidate,16256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:55+00:00
8088,curation_candidate,16263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8089,curation_candidate,10894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:55+00:00
8090,curation_candidate,15284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:55+00:00
8091,curation_candidate,16292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8092,curation_candidate,10914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:55+00:00
8093,curation_candidate,11725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8094,curation_candidate,16312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8095,curation_candidate,16317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8096,curation_candidate,16319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8097,curation_candidate,11728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8098,curation_candidate,10895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8099,curation_candidate,11078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8100,curation_candidate,11737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8101,curation_candidate,11747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8102,curation_candidate,10349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8103,curation_candidate,10495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8104,curation_candidate,10618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8105,curation_candidate,10642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8106,curation_candidate,11094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8107,curation_candidate,11144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8108,curation_candidate,11174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8109,curation_candidate,11188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8110,curation_candidate,11214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8111,curation_candidate,11759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8112,curation_candidate,11773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8113,curation_candidate,11804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8114,curation_candidate,11808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8115,curation_candidate,11815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8116,curation_candidate,11817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8117,curation_candidate,11819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8118,curation_candidate,11834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8119,curation_candidate,11889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8120,curation_candidate,11894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8121,curation_candidate,11901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8122,curation_candidate,11907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8123,curation_candidate,11923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8124,curation_candidate,11958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8125,curation_candidate,11986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8126,curation_candidate,11997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8127,curation_candidate,12009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8128,curation_candidate,12019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8129,curation_candidate,12022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8130,curation_candidate,12053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8131,curation_candidate,12061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8132,curation_candidate,12063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8133,curation_candidate,12084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8134,curation_candidate,12092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8135,curation_candidate,12096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8136,curation_candidate,12142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8137,curation_candidate,12151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8138,curation_candidate,12172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8139,curation_candidate,12203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8140,curation_candidate,12228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8141,curation_candidate,12244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:56+00:00
8142,curation_candidate,12246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8143,curation_candidate,12263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8144,curation_candidate,12269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8145,curation_candidate,12296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8146,curation_candidate,12297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8147,curation_candidate,12300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8148,curation_candidate,12302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8149,curation_candidate,12309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8150,curation_candidate,12317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8151,curation_candidate,12335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8152,curation_candidate,12344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8153,curation_candidate,12348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8154,curation_candidate,12357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8155,curation_candidate,12366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8156,curation_candidate,12370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8157,curation_candidate,12371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8158,curation_candidate,12396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8159,curation_candidate,12399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8160,curation_candidate,12408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8161,curation_candidate,12409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8162,curation_candidate,12413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8163,curation_candidate,12417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8164,curation_candidate,12420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8165,curation_candidate,12425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8166,curation_candidate,12440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8167,curation_candidate,12446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8168,curation_candidate,12452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8169,curation_candidate,12453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8170,curation_candidate,12472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8171,curation_candidate,12491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8172,curation_candidate,12518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8173,curation_candidate,12560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8174,curation_candidate,12562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8175,curation_candidate,12568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8176,curation_candidate,12597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8177,curation_candidate,12599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8178,curation_candidate,12605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8179,curation_candidate,12609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8180,curation_candidate,12612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8181,curation_candidate,12614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8182,curation_candidate,12626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8183,curation_candidate,12630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8184,curation_candidate,12632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8185,curation_candidate,12651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8186,curation_candidate,12657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8187,curation_candidate,12675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8188,curation_candidate,12681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8189,curation_candidate,12684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8190,curation_candidate,12689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8191,curation_candidate,12693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8192,curation_candidate,12701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8193,curation_candidate,12702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8194,curation_candidate,12703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8195,curation_candidate,12705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8196,curation_candidate,12710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8197,curation_candidate,12737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8198,curation_candidate,12740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8199,curation_candidate,12747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8200,curation_candidate,12760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8201,curation_candidate,12774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8202,curation_candidate,12775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8203,curation_candidate,12785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8204,curation_candidate,12787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8205,curation_candidate,12797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8206,curation_candidate,12798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8207,curation_candidate,12799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8208,curation_candidate,12855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8209,curation_candidate,12869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8210,curation_candidate,12874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8211,curation_candidate,12877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8212,curation_candidate,12885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8213,curation_candidate,12886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8214,curation_candidate,12892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8215,curation_candidate,12923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8216,curation_candidate,13032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8217,curation_candidate,13035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8218,curation_candidate,13059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8219,curation_candidate,13063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8220,curation_candidate,13083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8221,curation_candidate,13089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8222,curation_candidate,13101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8223,curation_candidate,15315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8224,curation_candidate,15346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8225,curation_candidate,15371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8226,curation_candidate,15374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8227,curation_candidate,15380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8228,curation_candidate,15385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8229,curation_candidate,10327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8230,curation_candidate,10351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8231,curation_candidate,10377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8232,curation_candidate,10415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8233,curation_candidate,10429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8234,curation_candidate,10551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8235,curation_candidate,10555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8236,curation_candidate,10621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8237,curation_candidate,10664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8238,curation_candidate,10687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8239,curation_candidate,10688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8240,curation_candidate,10719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8241,curation_candidate,10721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8242,curation_candidate,10722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8243,curation_candidate,10733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8244,curation_candidate,11109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8245,curation_candidate,11264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8246,curation_candidate,11268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8247,curation_candidate,11292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8248,curation_candidate,11345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8249,curation_candidate,11372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8250,curation_candidate,11395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8251,curation_candidate,11435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8252,curation_candidate,11439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8253,curation_candidate,13109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8254,curation_candidate,13110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8255,curation_candidate,13115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8256,curation_candidate,13118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8257,curation_candidate,13121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8258,curation_candidate,13138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8259,curation_candidate,13148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8260,curation_candidate,13154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8261,curation_candidate,13158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8262,curation_candidate,13160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8263,curation_candidate,13161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8264,curation_candidate,13162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8265,curation_candidate,13165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8266,curation_candidate,13173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8267,curation_candidate,13176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8268,curation_candidate,13180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8269,curation_candidate,13190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8270,curation_candidate,13191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8271,curation_candidate,13192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8272,curation_candidate,13194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8273,curation_candidate,13210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8274,curation_candidate,13211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8275,curation_candidate,13219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8276,curation_candidate,13232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8277,curation_candidate,13235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8278,curation_candidate,13241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8279,curation_candidate,13245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8280,curation_candidate,13253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8281,curation_candidate,13262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8282,curation_candidate,13264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8283,curation_candidate,13265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8284,curation_candidate,13266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8285,curation_candidate,13267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8286,curation_candidate,13274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8287,curation_candidate,13276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8288,curation_candidate,13286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8289,curation_candidate,13312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8290,curation_candidate,13313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8291,curation_candidate,13316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8292,curation_candidate,13319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8293,curation_candidate,13321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8294,curation_candidate,13333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8295,curation_candidate,13335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8296,curation_candidate,13345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8297,curation_candidate,13361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8298,curation_candidate,13370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8299,curation_candidate,13374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8300,curation_candidate,13376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8301,curation_candidate,13377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8302,curation_candidate,13378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8303,curation_candidate,13380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8304,curation_candidate,13382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8305,curation_candidate,13412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8306,curation_candidate,13423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8307,curation_candidate,13425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8308,curation_candidate,13435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8309,curation_candidate,13439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8310,curation_candidate,13440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8311,curation_candidate,13453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8312,curation_candidate,13491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8313,curation_candidate,13494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8314,curation_candidate,13499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8315,curation_candidate,13506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8316,curation_candidate,13513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8317,curation_candidate,13517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8318,curation_candidate,13542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8319,curation_candidate,13548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8320,curation_candidate,13556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8321,curation_candidate,13558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8322,curation_candidate,13562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8323,curation_candidate,13567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8324,curation_candidate,13573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8325,curation_candidate,13575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8326,curation_candidate,13577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8327,curation_candidate,13590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8328,curation_candidate,13596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8329,curation_candidate,13617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8330,curation_candidate,13630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8331,curation_candidate,13631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8332,curation_candidate,13643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8333,curation_candidate,13646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8334,curation_candidate,13648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8335,curation_candidate,13651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8336,curation_candidate,13667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8337,curation_candidate,13692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8338,curation_candidate,13695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8339,curation_candidate,13696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8340,curation_candidate,13703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8341,curation_candidate,13705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8342,curation_candidate,13714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8343,curation_candidate,13718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8344,curation_candidate,13720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8345,curation_candidate,13723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8346,curation_candidate,13724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8347,curation_candidate,13728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8348,curation_candidate,13753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8349,curation_candidate,13759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8350,curation_candidate,13765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8351,curation_candidate,13773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8352,curation_candidate,13780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8353,curation_candidate,13782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8354,curation_candidate,13800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8355,curation_candidate,13823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8356,curation_candidate,13828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8357,curation_candidate,13837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8358,curation_candidate,13848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8359,curation_candidate,13861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8360,curation_candidate,13867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8361,curation_candidate,13868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8362,curation_candidate,13870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8363,curation_candidate,13874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8364,curation_candidate,13875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8365,curation_candidate,13879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8366,curation_candidate,13880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8367,curation_candidate,13884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8368,curation_candidate,13891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8369,curation_candidate,13896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8370,curation_candidate,13925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8371,curation_candidate,13957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8372,curation_candidate,13969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8373,curation_candidate,13970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8374,curation_candidate,13977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8375,curation_candidate,13978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8376,curation_candidate,13987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8377,curation_candidate,14003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8378,curation_candidate,14004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8379,curation_candidate,14011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8380,curation_candidate,14017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8381,curation_candidate,14018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8382,curation_candidate,14020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8383,curation_candidate,14025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8384,curation_candidate,14031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8385,curation_candidate,14038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8386,curation_candidate,14051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8387,curation_candidate,14062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8388,curation_candidate,14069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8389,curation_candidate,14074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8390,curation_candidate,14089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8391,curation_candidate,14098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8392,curation_candidate,14103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8393,curation_candidate,14107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8394,curation_candidate,14115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8395,curation_candidate,14119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8396,curation_candidate,14122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8397,curation_candidate,14128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8398,curation_candidate,14145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8399,curation_candidate,14157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8400,curation_candidate,14164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8401,curation_candidate,14167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8402,curation_candidate,14175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8403,curation_candidate,14180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8404,curation_candidate,14187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8405,curation_candidate,14194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8406,curation_candidate,14206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8407,curation_candidate,14220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8408,curation_candidate,14233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8409,curation_candidate,14234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8410,curation_candidate,14240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8411,curation_candidate,14251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8412,curation_candidate,14253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8413,curation_candidate,14255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8414,curation_candidate,14271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8415,curation_candidate,14272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8416,curation_candidate,14274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8417,curation_candidate,14276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8418,curation_candidate,14278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8419,curation_candidate,14286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8420,curation_candidate,14321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8421,curation_candidate,14335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8422,curation_candidate,14336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8423,curation_candidate,14348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8424,curation_candidate,14349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8425,curation_candidate,14351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8426,curation_candidate,14367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8427,curation_candidate,14375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8428,curation_candidate,14383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8429,curation_candidate,14384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8430,curation_candidate,14388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8431,curation_candidate,14400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8432,curation_candidate,14404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:56+00:00
8433,curation_candidate,14412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8434,curation_candidate,14419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8435,curation_candidate,14420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8436,curation_candidate,14423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8437,curation_candidate,14426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8438,curation_candidate,15132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8439,curation_candidate,15148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8440,curation_candidate,15179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8441,curation_candidate,15390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8442,curation_candidate,15392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8443,curation_candidate,15394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8444,curation_candidate,15399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8445,curation_candidate,15400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8446,curation_candidate,15406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8447,curation_candidate,15410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8448,curation_candidate,15413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8449,curation_candidate,15421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8450,curation_candidate,15422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8451,curation_candidate,15432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8452,curation_candidate,15434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8453,curation_candidate,15448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8454,curation_candidate,15474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8455,curation_candidate,15493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8456,curation_candidate,15507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8457,curation_candidate,15533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8458,curation_candidate,15559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8459,curation_candidate,15563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8460,curation_candidate,15582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8461,curation_candidate,15583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8462,curation_candidate,15592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8463,curation_candidate,15608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8464,curation_candidate,15621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8465,curation_candidate,10441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8466,curation_candidate,10564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8467,curation_candidate,10570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:56+00:00
8468,curation_candidate,10747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8469,curation_candidate,10750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:56+00:00
8470,curation_candidate,10754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8471,curation_candidate,10757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:56+00:00
8472,curation_candidate,10761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8473,curation_candidate,10762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8474,curation_candidate,10763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8475,curation_candidate,10774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8476,curation_candidate,10975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8477,curation_candidate,10985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8478,curation_candidate,10990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8479,curation_candidate,10991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8480,curation_candidate,10993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8481,curation_candidate,11113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8482,curation_candidate,11494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8483,curation_candidate,11497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8484,curation_candidate,11505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8485,curation_candidate,11513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8486,curation_candidate,11521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8487,curation_candidate,11529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8488,curation_candidate,11530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8489,curation_candidate,11532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8490,curation_candidate,11545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8491,curation_candidate,11558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8492,curation_candidate,11761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8493,curation_candidate,14439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8494,curation_candidate,14444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8495,curation_candidate,14453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8496,curation_candidate,14491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8497,curation_candidate,14494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8498,curation_candidate,14495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8499,curation_candidate,14502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8500,curation_candidate,14512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8501,curation_candidate,14517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8502,curation_candidate,14525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8503,curation_candidate,14537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8504,curation_candidate,14539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8505,curation_candidate,14544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8506,curation_candidate,14547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8507,curation_candidate,14553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8508,curation_candidate,14572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8509,curation_candidate,14573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8510,curation_candidate,14577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8511,curation_candidate,14580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8512,curation_candidate,14596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8513,curation_candidate,14601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8514,curation_candidate,14609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8515,curation_candidate,14612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8516,curation_candidate,14618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8517,curation_candidate,14626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8518,curation_candidate,14632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8519,curation_candidate,14644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8520,curation_candidate,14651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8521,curation_candidate,14654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8522,curation_candidate,14655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8523,curation_candidate,14657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8524,curation_candidate,14659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8525,curation_candidate,14672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8526,curation_candidate,14678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8527,curation_candidate,14686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8528,curation_candidate,14687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8529,curation_candidate,14689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8530,curation_candidate,14693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8531,curation_candidate,14709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8532,curation_candidate,14712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8533,curation_candidate,14726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8534,curation_candidate,14728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8535,curation_candidate,14738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8536,curation_candidate,14742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8537,curation_candidate,14769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8538,curation_candidate,14777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8539,curation_candidate,14779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8540,curation_candidate,14782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:56+00:00
8541,curation_candidate,14784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8542,curation_candidate,14799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8543,curation_candidate,14820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8544,curation_candidate,14827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8545,curation_candidate,14835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8546,curation_candidate,14845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8547,curation_candidate,14849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8548,curation_candidate,14863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8549,curation_candidate,14870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8550,curation_candidate,14872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8551,curation_candidate,14876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8552,curation_candidate,14879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8553,curation_candidate,14895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8554,curation_candidate,14905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8555,curation_candidate,14909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8556,curation_candidate,14919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8557,curation_candidate,14936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8558,curation_candidate,14947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8559,curation_candidate,15632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8560,curation_candidate,15640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8561,curation_candidate,15645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8562,curation_candidate,15668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8563,curation_candidate,15671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8564,curation_candidate,15672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8565,curation_candidate,15676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8566,curation_candidate,15683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8567,curation_candidate,15692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8568,curation_candidate,15701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8569,curation_candidate,15707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8570,curation_candidate,15708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8571,curation_candidate,15721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8572,curation_candidate,10777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8573,curation_candidate,10838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8574,curation_candidate,11566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8575,curation_candidate,11571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8576,curation_candidate,11572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8577,curation_candidate,11573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8578,curation_candidate,11588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8579,curation_candidate,11590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8580,curation_candidate,14959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8581,curation_candidate,15028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8582,curation_candidate,15046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8583,curation_candidate,15050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8584,curation_candidate,15051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8585,curation_candidate,15077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8586,curation_candidate,15085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8587,curation_candidate,15087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8588,curation_candidate,15089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8589,curation_candidate,15222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8590,curation_candidate,15224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8591,curation_candidate,15229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8592,curation_candidate,15728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8593,curation_candidate,15729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8594,curation_candidate,15735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8595,curation_candidate,15737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8596,curation_candidate,15739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8597,curation_candidate,15744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8598,curation_candidate,15747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8599,curation_candidate,15750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8600,curation_candidate,15755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8601,curation_candidate,15757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8602,curation_candidate,15760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8603,curation_candidate,15768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8604,curation_candidate,15771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8605,curation_candidate,15789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8606,curation_candidate,15791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8607,curation_candidate,15814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8608,curation_candidate,15815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8609,curation_candidate,15826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8610,curation_candidate,15844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8611,curation_candidate,15874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8612,curation_candidate,15886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8613,curation_candidate,15894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8614,curation_candidate,15903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8615,curation_candidate,15914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8616,curation_candidate,15929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8617,curation_candidate,15946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8618,curation_candidate,10803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8619,curation_candidate,10813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8620,curation_candidate,10901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8621,curation_candidate,11025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8622,curation_candidate,11121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8623,curation_candidate,11606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8624,curation_candidate,11611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8625,curation_candidate,11621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8626,curation_candidate,11622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8627,curation_candidate,15953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8628,curation_candidate,15959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8629,curation_candidate,15966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8630,curation_candidate,15971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8631,curation_candidate,15977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8632,curation_candidate,15987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8633,curation_candidate,15989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8634,curation_candidate,15995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8635,curation_candidate,15998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8636,curation_candidate,16002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8637,curation_candidate,16003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8638,curation_candidate,16005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8639,curation_candidate,16006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8640,curation_candidate,16010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8641,curation_candidate,16013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8642,curation_candidate,16016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8643,curation_candidate,16017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8644,curation_candidate,16022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8645,curation_candidate,16024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8646,curation_candidate,16037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8647,curation_candidate,16050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8648,curation_candidate,16069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8649,curation_candidate,16071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8650,curation_candidate,10595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8651,curation_candidate,10814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8652,curation_candidate,10822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8653,curation_candidate,11037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8654,curation_candidate,11647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8655,curation_candidate,11657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8656,curation_candidate,11662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8657,curation_candidate,15116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8658,curation_candidate,16075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8659,curation_candidate,16080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8660,curation_candidate,16097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8661,curation_candidate,16100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8662,curation_candidate,16114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8663,curation_candidate,16122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8664,curation_candidate,16124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8665,curation_candidate,16131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8666,curation_candidate,16132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8667,curation_candidate,16133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8668,curation_candidate,16153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source support is introduction/background only,2026-06-02T15:59:56+00:00
8669,curation_candidate,16156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8670,curation_candidate,16157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8671,curation_candidate,16158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8672,curation_candidate,16165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8673,curation_candidate,16173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8674,curation_candidate,11045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8675,curation_candidate,11132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8676,curation_candidate,11676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8677,curation_candidate,11682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8678,curation_candidate,11695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8679,curation_candidate,15117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8680,curation_candidate,15139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8681,curation_candidate,16178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8682,curation_candidate,16182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8683,curation_candidate,16191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8684,curation_candidate,16193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8685,curation_candidate,16199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8686,curation_candidate,16202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8687,curation_candidate,16210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8688,curation_candidate,16213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8689,curation_candidate,15260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8690,curation_candidate,16249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8691,curation_candidate,16261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8692,curation_candidate,16270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8693,curation_candidate,16271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8694,curation_candidate,16273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8695,curation_candidate,15124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8696,curation_candidate,15283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8697,curation_candidate,15291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8698,curation_candidate,16284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8699,curation_candidate,16285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8700,curation_candidate,16296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8701,curation_candidate,16300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8702,curation_candidate,16301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8703,curation_candidate,11066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8704,curation_candidate,15125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8705,curation_candidate,16305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8706,curation_candidate,11069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8707,curation_candidate,11076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8708,curation_candidate,11740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8709,curation_candidate,10340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8710,curation_candidate,10456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8711,curation_candidate,10463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8712,curation_candidate,10473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8713,curation_candidate,10481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8714,curation_candidate,10493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8715,curation_candidate,10511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8716,curation_candidate,10619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8717,curation_candidate,10623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8718,curation_candidate,10626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8719,curation_candidate,10657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8720,curation_candidate,10846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8721,curation_candidate,10932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8722,curation_candidate,11153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8723,curation_candidate,11171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8724,curation_candidate,11173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8725,curation_candidate,11185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8726,curation_candidate,11189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8727,curation_candidate,11223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8728,curation_candidate,11232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8729,curation_candidate,11249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8730,curation_candidate,11251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8731,curation_candidate,11769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8732,curation_candidate,11772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8733,curation_candidate,11778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8734,curation_candidate,11779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8735,curation_candidate,11781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8736,curation_candidate,11784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8737,curation_candidate,11788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8738,curation_candidate,11803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8739,curation_candidate,11822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8740,curation_candidate,11825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8741,curation_candidate,11828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8742,curation_candidate,11845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8743,curation_candidate,11854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8744,curation_candidate,11869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8745,curation_candidate,11871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8746,curation_candidate,11874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8747,curation_candidate,11882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8748,curation_candidate,11884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8749,curation_candidate,11899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8750,curation_candidate,11903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8751,curation_candidate,11913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8752,curation_candidate,11920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8753,curation_candidate,11925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8754,curation_candidate,11928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8755,curation_candidate,11940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8756,curation_candidate,11944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8757,curation_candidate,11953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8758,curation_candidate,11963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8759,curation_candidate,11965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8760,curation_candidate,11966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8761,curation_candidate,11981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8762,curation_candidate,11989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8763,curation_candidate,11990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8764,curation_candidate,11991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8765,curation_candidate,12013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8766,curation_candidate,12014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8767,curation_candidate,12016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8768,curation_candidate,12044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8769,curation_candidate,12083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8770,curation_candidate,12086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8771,curation_candidate,12091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8772,curation_candidate,12094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8773,curation_candidate,12099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8774,curation_candidate,12109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8775,curation_candidate,12130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8776,curation_candidate,12133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8777,curation_candidate,12138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8778,curation_candidate,12139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8779,curation_candidate,12158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8780,curation_candidate,12165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8781,curation_candidate,12178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8782,curation_candidate,12181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8783,curation_candidate,12182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8784,curation_candidate,12194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8785,curation_candidate,12201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8786,curation_candidate,12204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8787,curation_candidate,12250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8788,curation_candidate,12262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8789,curation_candidate,12272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8790,curation_candidate,12284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8791,curation_candidate,12285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8792,curation_candidate,12289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8793,curation_candidate,12290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8794,curation_candidate,12311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8795,curation_candidate,12320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8796,curation_candidate,12325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8797,curation_candidate,12329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8798,curation_candidate,12338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8799,curation_candidate,12342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8800,curation_candidate,12363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8801,curation_candidate,12375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8802,curation_candidate,12389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8803,curation_candidate,12391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8804,curation_candidate,12429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8805,curation_candidate,12431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8806,curation_candidate,12436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8807,curation_candidate,12441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8808,curation_candidate,12450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8809,curation_candidate,12459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8810,curation_candidate,12460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8811,curation_candidate,12470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8812,curation_candidate,12471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8813,curation_candidate,12486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8814,curation_candidate,12496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8815,curation_candidate,12510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8816,curation_candidate,12513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8817,curation_candidate,12540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8818,curation_candidate,12547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8819,curation_candidate,12551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8820,curation_candidate,12553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8821,curation_candidate,12566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8822,curation_candidate,12569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8823,curation_candidate,12588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8824,curation_candidate,12591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8825,curation_candidate,12620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8826,curation_candidate,12624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8827,curation_candidate,12628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8828,curation_candidate,12629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8829,curation_candidate,12647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8830,curation_candidate,12654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8831,curation_candidate,12660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8832,curation_candidate,12667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8833,curation_candidate,12674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8834,curation_candidate,12677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8835,curation_candidate,12678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8836,curation_candidate,12682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8837,curation_candidate,12699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8838,curation_candidate,12724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8839,curation_candidate,12736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8840,curation_candidate,12741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8841,curation_candidate,12753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8842,curation_candidate,12755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8843,curation_candidate,12763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8844,curation_candidate,12776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8845,curation_candidate,12803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: mRNA-only source, not ASO/siRNA/oligonucleotide safety or off-target evidence",2026-06-02T15:59:56+00:00
8846,curation_candidate,12805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8847,curation_candidate,12810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8848,curation_candidate,12819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8849,curation_candidate,12823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8850,curation_candidate,12830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8851,curation_candidate,12838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8852,curation_candidate,12842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8853,curation_candidate,12864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8854,curation_candidate,12883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8855,curation_candidate,12884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8856,curation_candidate,12893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8857,curation_candidate,12904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8858,curation_candidate,12907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8859,curation_candidate,12916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8860,curation_candidate,12926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8861,curation_candidate,12937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8862,curation_candidate,12948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8863,curation_candidate,12953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8864,curation_candidate,12959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8865,curation_candidate,12964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8866,curation_candidate,12966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8867,curation_candidate,12976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8868,curation_candidate,12982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8869,curation_candidate,12987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8870,curation_candidate,12996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8871,curation_candidate,13001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8872,curation_candidate,13034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8873,curation_candidate,13037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8874,curation_candidate,13039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8875,curation_candidate,13040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8876,curation_candidate,13047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8877,curation_candidate,13050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8878,curation_candidate,13051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8879,curation_candidate,13054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8880,curation_candidate,13060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8881,curation_candidate,13065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8882,curation_candidate,13069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8883,curation_candidate,13080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8884,curation_candidate,13090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8885,curation_candidate,13092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8886,curation_candidate,13094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8887,curation_candidate,13106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8888,curation_candidate,15317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8889,curation_candidate,15319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8890,curation_candidate,15326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8891,curation_candidate,15327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8892,curation_candidate,15332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8893,curation_candidate,15365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8894,curation_candidate,15367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8895,curation_candidate,15368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8896,curation_candidate,15370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8897,curation_candidate,15378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8898,curation_candidate,15382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8899,curation_candidate,15775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8900,curation_candidate,15779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8901,curation_candidate,10322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8902,curation_candidate,10323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8903,curation_candidate,10408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8904,curation_candidate,10427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8905,curation_candidate,10557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8906,curation_candidate,10694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8907,curation_candidate,10713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8908,curation_candidate,10716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
8909,curation_candidate,10727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8910,curation_candidate,10730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8911,curation_candidate,10736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8912,curation_candidate,10737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8913,curation_candidate,10836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8914,curation_candidate,10900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8915,curation_candidate,10940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8916,curation_candidate,10945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8917,curation_candidate,11111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8918,curation_candidate,11289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8919,curation_candidate,11308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8920,curation_candidate,11336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8921,curation_candidate,11370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8922,curation_candidate,11382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8923,curation_candidate,11391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8924,curation_candidate,11426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8925,curation_candidate,11431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8926,curation_candidate,11462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8927,curation_candidate,11760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8928,curation_candidate,13139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8929,curation_candidate,13159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8930,curation_candidate,13200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8931,curation_candidate,13209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8932,curation_candidate,13228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8933,curation_candidate,13281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8934,curation_candidate,13290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8935,curation_candidate,13297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8936,curation_candidate,13325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8937,curation_candidate,13343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8938,curation_candidate,13350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8939,curation_candidate,13372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8940,curation_candidate,13373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8941,curation_candidate,13389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8942,curation_candidate,13402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8943,curation_candidate,13408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8944,curation_candidate,13414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8945,curation_candidate,13420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8946,curation_candidate,13436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8947,curation_candidate,13447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8948,curation_candidate,13455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8949,curation_candidate,13459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8950,curation_candidate,13460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8951,curation_candidate,13464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8952,curation_candidate,13480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8953,curation_candidate,13483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8954,curation_candidate,13484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8955,curation_candidate,13486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8956,curation_candidate,13492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8957,curation_candidate,13529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8958,curation_candidate,13532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8959,curation_candidate,13534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8960,curation_candidate,13538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8961,curation_candidate,13543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8962,curation_candidate,13546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8963,curation_candidate,13555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8964,curation_candidate,13561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8965,curation_candidate,13580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8966,curation_candidate,13581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8967,curation_candidate,13586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8968,curation_candidate,13593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8969,curation_candidate,13609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8970,curation_candidate,13620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8971,curation_candidate,13629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8972,curation_candidate,13637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8973,curation_candidate,13671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8974,curation_candidate,13707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8975,curation_candidate,13708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8976,curation_candidate,13711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8977,curation_candidate,13726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8978,curation_candidate,13742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8979,curation_candidate,13746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8980,curation_candidate,13756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8981,curation_candidate,13776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8982,curation_candidate,13808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8983,curation_candidate,13809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8984,curation_candidate,13812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8985,curation_candidate,13819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8986,curation_candidate,13843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8987,curation_candidate,13844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8988,curation_candidate,13853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8989,curation_candidate,13855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
8990,curation_candidate,13856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
8991,curation_candidate,13869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8992,curation_candidate,13886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8993,curation_candidate,13888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
8994,curation_candidate,13901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8995,curation_candidate,13908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
8996,curation_candidate,13921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
8997,curation_candidate,13935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8998,curation_candidate,13937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
8999,curation_candidate,13961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety-like term is part of disease efficacy/cell-killing readout,2026-06-02T15:59:56+00:00
9000,curation_candidate,13963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
9001,curation_candidate,13972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
9002,curation_candidate,13985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9003,curation_candidate,14002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9004,curation_candidate,14009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T15:59:56+00:00
9005,curation_candidate,14015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
9006,curation_candidate,14028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
9007,curation_candidate,14035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9008,curation_candidate,14041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9009,curation_candidate,14054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9010,curation_candidate,14073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9011,curation_candidate,14078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9012,curation_candidate,14081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no therapeutic oligonucleotide/siRNA/ASO safety modality supported by source context,2026-06-02T15:59:56+00:00
9013,curation_candidate,14083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
9014,curation_candidate,14099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
9015,curation_candidate,14108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9016,curation_candidate,14116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9017,curation_candidate,14131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
9018,curation_candidate,14158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
9019,curation_candidate,14161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
9020,curation_candidate,14163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T15:59:56+00:00
9021,curation_candidate,14172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: safety endpoint is too generic or unsupported,2026-06-02T15:59:56+00:00
9022,curation_candidate,14185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary release evidence",2026-06-02T15:59:56+00:00
9023,curation_candidate,14189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source location does not contain a toxicity or safety endpoint,2026-06-02T15:59:56+00:00
9024,offtarget_evidence,275,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for transcriptome-level off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9025,offtarget_evidence,276,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 4: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9026,offtarget_evidence,277,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9027,offtarget_evidence,278,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9028,offtarget_evidence,279,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for seed-mediated off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9029,offtarget_evidence,280,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for seed-mediated off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9030,offtarget_evidence,281,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for seed-mediated off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9031,offtarget_evidence,282,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9032,offtarget_evidence,283,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for transcriptome-level off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9033,offtarget_evidence,284,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9034,offtarget_evidence,285,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 3: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9035,offtarget_evidence,286,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9036,offtarget_evidence,287,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9037,offtarget_evidence,288,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9038,offtarget_evidence,289,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for seed-mediated off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9039,offtarget_evidence,290,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 5: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9040,offtarget_evidence,291,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9041,offtarget_evidence,292,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9042,offtarget_evidence,293,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9043,offtarget_evidence,294,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 2: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9044,offtarget_evidence,295,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9045,offtarget_evidence,296,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for seed-mediated off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9046,offtarget_evidence,297,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9047,offtarget_evidence,298,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for transcriptome-level off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9048,offtarget_evidence,299,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9049,offtarget_evidence,300,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9050,offtarget_evidence,301,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9051,offtarget_evidence,302,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 6: primary off-target support for seed-mediated off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9052,offtarget_evidence,303,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9053,offtarget_evidence,304,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9054,offtarget_evidence,305,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9055,offtarget_evidence,306,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9056,offtarget_evidence,307,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for transcriptome-level off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9057,offtarget_evidence,308,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9058,offtarget_evidence,309,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9059,offtarget_evidence,310,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 8: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9060,offtarget_evidence,311,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9061,offtarget_evidence,312,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9062,offtarget_evidence,313,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9063,offtarget_evidence,314,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9064,offtarget_evidence,315,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9065,offtarget_evidence,316,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9066,offtarget_evidence,317,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9067,offtarget_evidence,318,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract sentence 4: primary off-target support for transcriptome-level off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9068,offtarget_evidence,319,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9069,offtarget_evidence,320,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9070,offtarget_evidence,321,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9071,offtarget_evidence,322,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9072,offtarget_evidence,323,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9073,offtarget_evidence,324,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9074,offtarget_evidence,325,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for transcriptome-level off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9075,offtarget_evidence,326,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9076,offtarget_evidence,327,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9077,offtarget_evidence,328,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for hybridization/mismatch off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9078,offtarget_evidence,329,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for off-target evidence in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9079,offtarget_evidence,330,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Verified PubMed abstract evidence at PubMed abstract: primary off-target support for transcriptome-level off-target effect in a molecule-specific oligonucleotide context.,2026-06-02T18:08:40+00:00
9080,curation_candidate,21390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9081,curation_candidate,24247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9082,curation_candidate,17890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9083,curation_candidate,18941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9084,curation_candidate,19173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9085,curation_candidate,19576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9086,curation_candidate,20027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9087,curation_candidate,20757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9088,curation_candidate,21083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9089,curation_candidate,21638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9090,curation_candidate,22317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9091,curation_candidate,22511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9092,curation_candidate,23782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9093,curation_candidate,24109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9094,curation_candidate,25180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9095,curation_candidate,26505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9096,curation_candidate,30385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9097,curation_candidate,32582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9098,curation_candidate,34240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9099,curation_candidate,36621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9100,curation_candidate,37322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9101,curation_candidate,16372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9102,curation_candidate,16805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9103,curation_candidate,17205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9104,curation_candidate,17254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9105,curation_candidate,17977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9106,curation_candidate,19281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9107,curation_candidate,19998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9108,curation_candidate,20722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9109,curation_candidate,21503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9110,curation_candidate,22981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9111,curation_candidate,23293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9112,curation_candidate,24285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9113,curation_candidate,24388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9114,curation_candidate,25030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9115,curation_candidate,25715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9116,curation_candidate,26532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9117,curation_candidate,27145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9118,curation_candidate,28798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
9119,curation_candidate,28831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9120,curation_candidate,29221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9121,curation_candidate,29777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9122,curation_candidate,29884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9123,curation_candidate,33978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9124,curation_candidate,33986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9125,curation_candidate,34927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9126,curation_candidate,16361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9127,curation_candidate,16366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9128,curation_candidate,16551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9129,curation_candidate,17059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9130,curation_candidate,17176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9131,curation_candidate,18894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9132,curation_candidate,18953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9133,curation_candidate,19468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9134,curation_candidate,19493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9135,curation_candidate,21362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9136,curation_candidate,22011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9137,curation_candidate,22402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9138,curation_candidate,24153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9139,curation_candidate,24194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9140,curation_candidate,24275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9141,curation_candidate,24438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9142,curation_candidate,24722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9143,curation_candidate,24816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9144,curation_candidate,25726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9145,curation_candidate,26878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9146,curation_candidate,27506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9147,curation_candidate,28379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9148,curation_candidate,28622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9149,curation_candidate,29226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9150,curation_candidate,29419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9151,curation_candidate,30428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9152,curation_candidate,30491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9153,curation_candidate,33245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9154,curation_candidate,33400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9155,curation_candidate,35082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9156,curation_candidate,16424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9157,curation_candidate,16830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9158,curation_candidate,16898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
9159,curation_candidate,17023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9160,curation_candidate,17903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9161,curation_candidate,18207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9162,curation_candidate,18656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9163,curation_candidate,18829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9164,curation_candidate,18882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9165,curation_candidate,19211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9166,curation_candidate,19660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9167,curation_candidate,19744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9168,curation_candidate,19827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9169,curation_candidate,20036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9170,curation_candidate,20414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9171,curation_candidate,20635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9172,curation_candidate,21240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9173,curation_candidate,21554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9174,curation_candidate,21877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9175,curation_candidate,22505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9176,curation_candidate,22556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9177,curation_candidate,22892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9178,curation_candidate,23012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9179,curation_candidate,23032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9180,curation_candidate,23094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9181,curation_candidate,23147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9182,curation_candidate,23601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9183,curation_candidate,23743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9184,curation_candidate,24639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9185,curation_candidate,24894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9186,curation_candidate,25069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9187,curation_candidate,25648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9188,curation_candidate,25671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9189,curation_candidate,25694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9190,curation_candidate,25797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9191,curation_candidate,26502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9192,curation_candidate,27306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9193,curation_candidate,27324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9194,curation_candidate,27395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9195,curation_candidate,27828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9196,curation_candidate,28072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9197,curation_candidate,28170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9198,curation_candidate,28395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9199,curation_candidate,28585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
9200,curation_candidate,28652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9201,curation_candidate,28695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9202,curation_candidate,28793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
9203,curation_candidate,28883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9204,curation_candidate,28934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9205,curation_candidate,28996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9206,curation_candidate,29383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9207,curation_candidate,29769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9208,curation_candidate,30245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9209,curation_candidate,30625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9210,curation_candidate,30832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9211,curation_candidate,31042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9212,curation_candidate,31867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9213,curation_candidate,32101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9214,curation_candidate,33788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9215,curation_candidate,35872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9216,curation_candidate,37009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9217,curation_candidate,37088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9218,curation_candidate,16333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9219,curation_candidate,16455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9220,curation_candidate,16860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9221,curation_candidate,16997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9222,curation_candidate,17940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9223,curation_candidate,18037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9224,curation_candidate,18457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9225,curation_candidate,19064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9226,curation_candidate,19079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9227,curation_candidate,19575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9228,curation_candidate,19840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9229,curation_candidate,20038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9230,curation_candidate,21040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9231,curation_candidate,21056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9232,curation_candidate,21477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
9233,curation_candidate,21654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9234,curation_candidate,24162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9235,curation_candidate,24440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9236,curation_candidate,24666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9237,curation_candidate,25027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9238,curation_candidate,25070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9239,curation_candidate,25183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9240,curation_candidate,25452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9241,curation_candidate,25722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9242,curation_candidate,25809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9243,curation_candidate,25848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9244,curation_candidate,27124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9245,curation_candidate,27634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9246,curation_candidate,27861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9247,curation_candidate,28334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9248,curation_candidate,28537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9249,curation_candidate,28594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9250,curation_candidate,28999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9251,curation_candidate,29117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9252,curation_candidate,29255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9253,curation_candidate,29288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9254,curation_candidate,29381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9255,curation_candidate,29524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9256,curation_candidate,30318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9257,curation_candidate,31330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9258,curation_candidate,31994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9259,curation_candidate,32043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9260,curation_candidate,32431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9261,curation_candidate,32856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9262,curation_candidate,32972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9263,curation_candidate,34730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9264,curation_candidate,35434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9265,curation_candidate,35749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9266,curation_candidate,35821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9267,curation_candidate,36194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9268,curation_candidate,36238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9269,curation_candidate,36549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9270,curation_candidate,36565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9271,curation_candidate,37151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9272,curation_candidate,37960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9273,curation_candidate,16453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9274,curation_candidate,16464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9275,curation_candidate,16810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9276,curation_candidate,16833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9277,curation_candidate,17058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9278,curation_candidate,17137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9279,curation_candidate,18385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9280,curation_candidate,19347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9281,curation_candidate,19528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9282,curation_candidate,19648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9283,curation_candidate,20060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9284,curation_candidate,20350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9285,curation_candidate,20725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9286,curation_candidate,22007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9287,curation_candidate,22047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9288,curation_candidate,22441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9289,curation_candidate,22542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9290,curation_candidate,22703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9291,curation_candidate,23023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9292,curation_candidate,23299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9293,curation_candidate,23452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9294,curation_candidate,23613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9295,curation_candidate,23923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9296,curation_candidate,23949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9297,curation_candidate,25164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9298,curation_candidate,25624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9299,curation_candidate,25747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9300,curation_candidate,26085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9301,curation_candidate,26125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9302,curation_candidate,26349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9303,curation_candidate,26408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9304,curation_candidate,26988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9305,curation_candidate,27129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9306,curation_candidate,27292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9307,curation_candidate,27996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9308,curation_candidate,28017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9309,curation_candidate,28162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9310,curation_candidate,28336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9311,curation_candidate,28833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9312,curation_candidate,28853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9313,curation_candidate,28855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9314,curation_candidate,29046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9315,curation_candidate,29406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9316,curation_candidate,29575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9317,curation_candidate,29770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9318,curation_candidate,29776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9319,curation_candidate,30375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9320,curation_candidate,30527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9321,curation_candidate,31013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9322,curation_candidate,31528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9323,curation_candidate,31741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9324,curation_candidate,31878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9325,curation_candidate,34469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9326,curation_candidate,34809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9327,curation_candidate,35452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9328,curation_candidate,35565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9329,curation_candidate,36499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9330,curation_candidate,37068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9331,curation_candidate,37405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9332,curation_candidate,37669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9333,curation_candidate,37839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9334,curation_candidate,16365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9335,curation_candidate,16405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9336,curation_candidate,16417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9337,curation_candidate,16505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9338,curation_candidate,16515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9339,curation_candidate,16666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9340,curation_candidate,18248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9341,curation_candidate,18496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9342,curation_candidate,18506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9343,curation_candidate,18625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9344,curation_candidate,18632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9345,curation_candidate,19606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9346,curation_candidate,19805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9347,curation_candidate,20203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9348,curation_candidate,20701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9349,curation_candidate,20830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9350,curation_candidate,20993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9351,curation_candidate,21714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9352,curation_candidate,22295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9353,curation_candidate,22589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9354,curation_candidate,22806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9355,curation_candidate,23713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9356,curation_candidate,23884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9357,curation_candidate,25894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9358,curation_candidate,25963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9359,curation_candidate,26099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9360,curation_candidate,26353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9361,curation_candidate,26384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9362,curation_candidate,26394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9363,curation_candidate,26425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9364,curation_candidate,26571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9365,curation_candidate,26891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9366,curation_candidate,26935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9367,curation_candidate,27125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9368,curation_candidate,27180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9369,curation_candidate,27243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9370,curation_candidate,27323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9371,curation_candidate,27442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9372,curation_candidate,27804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9373,curation_candidate,27974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9374,curation_candidate,28070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9375,curation_candidate,28335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9376,curation_candidate,28380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9377,curation_candidate,28468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9378,curation_candidate,28556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9379,curation_candidate,28562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9380,curation_candidate,28861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9381,curation_candidate,29053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9382,curation_candidate,29091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9383,curation_candidate,29120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9384,curation_candidate,29183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9385,curation_candidate,29475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9386,curation_candidate,29772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9387,curation_candidate,29783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9388,curation_candidate,29846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9389,curation_candidate,29905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9390,curation_candidate,29911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9391,curation_candidate,30546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9392,curation_candidate,31266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9393,curation_candidate,31301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9394,curation_candidate,32295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9395,curation_candidate,32347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9396,curation_candidate,32527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9397,curation_candidate,32920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9398,curation_candidate,35120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9399,curation_candidate,36688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9400,curation_candidate,37110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9401,curation_candidate,37353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9402,curation_candidate,38278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9403,curation_candidate,16330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9404,curation_candidate,16510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9405,curation_candidate,16576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9406,curation_candidate,16619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9407,curation_candidate,16790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9408,curation_candidate,16834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9409,curation_candidate,16863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9410,curation_candidate,16905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9411,curation_candidate,16912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9412,curation_candidate,17066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9413,curation_candidate,17375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9414,curation_candidate,17617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9415,curation_candidate,17714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9416,curation_candidate,17803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9417,curation_candidate,17833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9418,curation_candidate,18785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9419,curation_candidate,18990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9420,curation_candidate,19007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9421,curation_candidate,19116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9422,curation_candidate,19413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9423,curation_candidate,20097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9424,curation_candidate,20889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9425,curation_candidate,21059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9426,curation_candidate,21921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9427,curation_candidate,22008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9428,curation_candidate,22281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9429,curation_candidate,22545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9430,curation_candidate,22836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9431,curation_candidate,23657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9432,curation_candidate,23723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9433,curation_candidate,24040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9434,curation_candidate,24265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9435,curation_candidate,24379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9436,curation_candidate,24402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9437,curation_candidate,24687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9438,curation_candidate,24759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9439,curation_candidate,24786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9440,curation_candidate,24811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9441,curation_candidate,24922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9442,curation_candidate,25832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9443,curation_candidate,25971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9444,curation_candidate,26433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9445,curation_candidate,26447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9446,curation_candidate,26453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9447,curation_candidate,26814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9448,curation_candidate,26932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9449,curation_candidate,27020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9450,curation_candidate,27303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9451,curation_candidate,27343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9452,curation_candidate,27387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9453,curation_candidate,27738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9454,curation_candidate,27790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9455,curation_candidate,27907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9456,curation_candidate,28343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9457,curation_candidate,28531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
9458,curation_candidate,28582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9459,curation_candidate,28659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9460,curation_candidate,28718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9461,curation_candidate,28727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9462,curation_candidate,29455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9463,curation_candidate,29810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
9464,curation_candidate,29821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9465,curation_candidate,30516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9466,curation_candidate,31369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9467,curation_candidate,31499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9468,curation_candidate,31942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9469,curation_candidate,32058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9470,curation_candidate,33500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9471,curation_candidate,33602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9472,curation_candidate,34286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9473,curation_candidate,34353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9474,curation_candidate,35839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9475,curation_candidate,36615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9476,curation_candidate,16394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9477,curation_candidate,16404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9478,curation_candidate,16512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9479,curation_candidate,16585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9480,curation_candidate,16624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9481,curation_candidate,16987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9482,curation_candidate,17204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9483,curation_candidate,17248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9484,curation_candidate,17307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9485,curation_candidate,17573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9486,curation_candidate,17583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9487,curation_candidate,17612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9488,curation_candidate,17788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9489,curation_candidate,17976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9490,curation_candidate,18006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9491,curation_candidate,18094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9492,curation_candidate,18230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9493,curation_candidate,18324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9494,curation_candidate,18607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9495,curation_candidate,18713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9496,curation_candidate,19004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9497,curation_candidate,19020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9498,curation_candidate,19025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9499,curation_candidate,19272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9500,curation_candidate,19581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9501,curation_candidate,19914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9502,curation_candidate,20168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9503,curation_candidate,21038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9504,curation_candidate,21101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9505,curation_candidate,21343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9506,curation_candidate,21536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9507,curation_candidate,22185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9508,curation_candidate,22210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9509,curation_candidate,22282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9510,curation_candidate,22340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9511,curation_candidate,22484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9512,curation_candidate,22493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9513,curation_candidate,22800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9514,curation_candidate,23126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9515,curation_candidate,23308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9516,curation_candidate,23568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9517,curation_candidate,25185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9518,curation_candidate,25307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9519,curation_candidate,25608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9520,curation_candidate,26377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9521,curation_candidate,26421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
9522,curation_candidate,26430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9523,curation_candidate,26474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9524,curation_candidate,26542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9525,curation_candidate,26660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9526,curation_candidate,26778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9527,curation_candidate,26885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9528,curation_candidate,26903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9529,curation_candidate,27095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9530,curation_candidate,27099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9531,curation_candidate,27190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9532,curation_candidate,27233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9533,curation_candidate,27335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9534,curation_candidate,27554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9535,curation_candidate,27818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9536,curation_candidate,27819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9537,curation_candidate,28341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9538,curation_candidate,28592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9539,curation_candidate,28613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9540,curation_candidate,28686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9541,curation_candidate,28713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9542,curation_candidate,28806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9543,curation_candidate,28824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9544,curation_candidate,28863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9545,curation_candidate,29232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9546,curation_candidate,29278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9547,curation_candidate,29767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9548,curation_candidate,30075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9549,curation_candidate,30628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9550,curation_candidate,30867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9551,curation_candidate,31082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9552,curation_candidate,31452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9553,curation_candidate,31461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9554,curation_candidate,32523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9555,curation_candidate,32830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9556,curation_candidate,33363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9557,curation_candidate,33565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9558,curation_candidate,34954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9559,curation_candidate,35287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9560,curation_candidate,36193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9561,curation_candidate,36608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9562,curation_candidate,36742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9563,curation_candidate,36833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9564,curation_candidate,36977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9565,curation_candidate,37013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9566,curation_candidate,37039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9567,curation_candidate,37273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9568,curation_candidate,37826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9569,curation_candidate,37911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9570,curation_candidate,37984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9571,curation_candidate,38124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9572,curation_candidate,16353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9573,curation_candidate,16373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9574,curation_candidate,16430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9575,curation_candidate,16533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9576,curation_candidate,16549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9577,curation_candidate,16676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9578,curation_candidate,16739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9579,curation_candidate,16871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9580,curation_candidate,17155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9581,curation_candidate,17243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9582,curation_candidate,17403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9583,curation_candidate,17597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9584,curation_candidate,17653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9585,curation_candidate,17752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9586,curation_candidate,17838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9587,curation_candidate,17871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9588,curation_candidate,17947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9589,curation_candidate,18336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9590,curation_candidate,18491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9591,curation_candidate,18519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9592,curation_candidate,18566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9593,curation_candidate,18643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9594,curation_candidate,18794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9595,curation_candidate,19186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9596,curation_candidate,19476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9597,curation_candidate,19636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9598,curation_candidate,19701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9599,curation_candidate,20022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9600,curation_candidate,20070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9601,curation_candidate,20340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9602,curation_candidate,20595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9603,curation_candidate,20946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9604,curation_candidate,21856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9605,curation_candidate,21931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9606,curation_candidate,21980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9607,curation_candidate,21981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9608,curation_candidate,22527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9609,curation_candidate,22568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9610,curation_candidate,22801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9611,curation_candidate,22816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9612,curation_candidate,23399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9613,curation_candidate,23555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9614,curation_candidate,23679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9615,curation_candidate,24097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9616,curation_candidate,24170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9617,curation_candidate,24500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9618,curation_candidate,24713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9619,curation_candidate,24902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9620,curation_candidate,25036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9621,curation_candidate,25158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9622,curation_candidate,25346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9623,curation_candidate,25360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9624,curation_candidate,25409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9625,curation_candidate,25488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9626,curation_candidate,25674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9627,curation_candidate,26001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9628,curation_candidate,26038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
9629,curation_candidate,26268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9630,curation_candidate,26286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9631,curation_candidate,26420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9632,curation_candidate,26652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9633,curation_candidate,26666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9634,curation_candidate,27055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9635,curation_candidate,27165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9636,curation_candidate,27200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9637,curation_candidate,27269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9638,curation_candidate,27271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9639,curation_candidate,27316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9640,curation_candidate,27368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9641,curation_candidate,27595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9642,curation_candidate,27777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9643,curation_candidate,28110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9644,curation_candidate,28203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9645,curation_candidate,28978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9646,curation_candidate,29159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9647,curation_candidate,29609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9648,curation_candidate,29811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9649,curation_candidate,30107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9650,curation_candidate,31415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9651,curation_candidate,31916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9652,curation_candidate,32367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9653,curation_candidate,32603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9654,curation_candidate,32638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9655,curation_candidate,33109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9656,curation_candidate,34169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9657,curation_candidate,34365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9658,curation_candidate,34638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9659,curation_candidate,35344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9660,curation_candidate,35486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9661,curation_candidate,35720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9662,curation_candidate,35816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9663,curation_candidate,36708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9664,curation_candidate,36759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9665,curation_candidate,36793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9666,curation_candidate,36962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9667,curation_candidate,36989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
9668,curation_candidate,37086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9669,curation_candidate,37268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9670,curation_candidate,37386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9671,curation_candidate,37578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9672,curation_candidate,38300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9673,curation_candidate,16364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9674,curation_candidate,16385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9675,curation_candidate,16406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9676,curation_candidate,16435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
9677,curation_candidate,16479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9678,curation_candidate,16522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9679,curation_candidate,16581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9680,curation_candidate,16695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9681,curation_candidate,16715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9682,curation_candidate,16736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9683,curation_candidate,16775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9684,curation_candidate,16831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9685,curation_candidate,17095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9686,curation_candidate,17132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
9687,curation_candidate,17154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9688,curation_candidate,17442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9689,curation_candidate,17955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9690,curation_candidate,18163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9691,curation_candidate,18422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9692,curation_candidate,18608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9693,curation_candidate,18811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9694,curation_candidate,19006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9695,curation_candidate,19107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9696,curation_candidate,19212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9697,curation_candidate,19244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9698,curation_candidate,19247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9699,curation_candidate,19296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9700,curation_candidate,19401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9701,curation_candidate,19475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9702,curation_candidate,19556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9703,curation_candidate,19718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9704,curation_candidate,19774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9705,curation_candidate,19949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9706,curation_candidate,19968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9707,curation_candidate,21154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9708,curation_candidate,21764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9709,curation_candidate,21783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9710,curation_candidate,21857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9711,curation_candidate,21915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9712,curation_candidate,22065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9713,curation_candidate,22403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9714,curation_candidate,22587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9715,curation_candidate,22879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9716,curation_candidate,23097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9717,curation_candidate,23870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9718,curation_candidate,23888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9719,curation_candidate,24039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9720,curation_candidate,24061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9721,curation_candidate,24099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9722,curation_candidate,24378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9723,curation_candidate,24814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9724,curation_candidate,24821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9725,curation_candidate,25102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9726,curation_candidate,25737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9727,curation_candidate,26171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9728,curation_candidate,26428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9729,curation_candidate,26437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9730,curation_candidate,26598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9731,curation_candidate,26619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9732,curation_candidate,26780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9733,curation_candidate,26902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9734,curation_candidate,26964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9735,curation_candidate,27032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9736,curation_candidate,27034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9737,curation_candidate,27203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9738,curation_candidate,27318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9739,curation_candidate,27510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9740,curation_candidate,27638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9741,curation_candidate,27957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9742,curation_candidate,28062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9743,curation_candidate,28236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9744,curation_candidate,28612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9745,curation_candidate,28952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9746,curation_candidate,29302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9747,curation_candidate,29800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9748,curation_candidate,29813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9749,curation_candidate,30422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9750,curation_candidate,30885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9751,curation_candidate,31059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9752,curation_candidate,31173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9753,curation_candidate,31368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9754,curation_candidate,31928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9755,curation_candidate,33196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9756,curation_candidate,33380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9757,curation_candidate,33454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9758,curation_candidate,33662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9759,curation_candidate,33821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9760,curation_candidate,33895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9761,curation_candidate,34263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9762,curation_candidate,34319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9763,curation_candidate,34562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9764,curation_candidate,35096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9765,curation_candidate,35312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9766,curation_candidate,35978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9767,curation_candidate,36004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9768,curation_candidate,36310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9769,curation_candidate,36455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9770,curation_candidate,36739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9771,curation_candidate,36850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9772,curation_candidate,36862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9773,curation_candidate,36926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9774,curation_candidate,37049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9775,curation_candidate,37084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9776,curation_candidate,37130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9777,curation_candidate,37159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9778,curation_candidate,37310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9779,curation_candidate,37563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9780,curation_candidate,37740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9781,curation_candidate,37837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9782,curation_candidate,38277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9783,curation_candidate,16469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9784,curation_candidate,16554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9785,curation_candidate,16584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9786,curation_candidate,16604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9787,curation_candidate,16651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9788,curation_candidate,16759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9789,curation_candidate,17273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9790,curation_candidate,17347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9791,curation_candidate,17385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
9792,curation_candidate,17386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9793,curation_candidate,17667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9794,curation_candidate,17694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9795,curation_candidate,17804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9796,curation_candidate,17945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9797,curation_candidate,18023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9798,curation_candidate,18142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9799,curation_candidate,18776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9800,curation_candidate,18789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9801,curation_candidate,18880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9802,curation_candidate,19083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9803,curation_candidate,19267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9804,curation_candidate,19361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9805,curation_candidate,19518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9806,curation_candidate,19688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
9807,curation_candidate,19844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9808,curation_candidate,20005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9809,curation_candidate,20302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9810,curation_candidate,20690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9811,curation_candidate,20703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9812,curation_candidate,20788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9813,curation_candidate,21264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9814,curation_candidate,21320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9815,curation_candidate,21442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9816,curation_candidate,21529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9817,curation_candidate,21711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9818,curation_candidate,22324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9819,curation_candidate,22359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9820,curation_candidate,22399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9821,curation_candidate,22532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9822,curation_candidate,22603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9823,curation_candidate,22634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9824,curation_candidate,23035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9825,curation_candidate,23297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
9826,curation_candidate,23301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9827,curation_candidate,23319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9828,curation_candidate,23507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9829,curation_candidate,23535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9830,curation_candidate,23687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9831,curation_candidate,23914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9832,curation_candidate,23984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9833,curation_candidate,24095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9834,curation_candidate,24403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9835,curation_candidate,24426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9836,curation_candidate,24558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9837,curation_candidate,24578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9838,curation_candidate,24671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9839,curation_candidate,24906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9840,curation_candidate,25133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9841,curation_candidate,25163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9842,curation_candidate,25287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9843,curation_candidate,25352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9844,curation_candidate,25415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9845,curation_candidate,26008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9846,curation_candidate,26364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9847,curation_candidate,26427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9848,curation_candidate,26596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9849,curation_candidate,26924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9850,curation_candidate,27051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9851,curation_candidate,27223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9852,curation_candidate,27361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9853,curation_candidate,27545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9854,curation_candidate,27844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9855,curation_candidate,28191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9856,curation_candidate,28366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9857,curation_candidate,28445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9858,curation_candidate,28655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9859,curation_candidate,28764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9860,curation_candidate,29345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9861,curation_candidate,29802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9862,curation_candidate,29988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9863,curation_candidate,30284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9864,curation_candidate,31234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9865,curation_candidate,31740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9866,curation_candidate,32194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9867,curation_candidate,32454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9868,curation_candidate,32507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9869,curation_candidate,33014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9870,curation_candidate,33045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9871,curation_candidate,33211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9872,curation_candidate,33327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9873,curation_candidate,34268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9874,curation_candidate,34364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9875,curation_candidate,34668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9876,curation_candidate,34824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9877,curation_candidate,34910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9878,curation_candidate,35081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9879,curation_candidate,35460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9880,curation_candidate,35504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9881,curation_candidate,35629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9882,curation_candidate,35731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9883,curation_candidate,35832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9884,curation_candidate,35904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9885,curation_candidate,36070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9886,curation_candidate,36418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9887,curation_candidate,36420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9888,curation_candidate,36422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9889,curation_candidate,36432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9890,curation_candidate,36505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9891,curation_candidate,36576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9892,curation_candidate,36610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9893,curation_candidate,36612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9894,curation_candidate,36701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9895,curation_candidate,36730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9896,curation_candidate,36945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9897,curation_candidate,36975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9898,curation_candidate,37002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9899,curation_candidate,37030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9900,curation_candidate,37041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9901,curation_candidate,37074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9902,curation_candidate,37081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9903,curation_candidate,37082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9904,curation_candidate,37548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9905,curation_candidate,37855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9906,curation_candidate,38193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9907,curation_candidate,38288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9908,curation_candidate,16328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9909,curation_candidate,16381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9910,curation_candidate,16454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9911,curation_candidate,16481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9912,curation_candidate,16626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
9913,curation_candidate,16641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9914,curation_candidate,16744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9915,curation_candidate,16934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9916,curation_candidate,17392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9917,curation_candidate,17432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9918,curation_candidate,17511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9919,curation_candidate,17673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9920,curation_candidate,17777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9921,curation_candidate,17898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9922,curation_candidate,18004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9923,curation_candidate,18097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9924,curation_candidate,18149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9925,curation_candidate,18220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9926,curation_candidate,18226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9927,curation_candidate,18372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9928,curation_candidate,18411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9929,curation_candidate,18968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9930,curation_candidate,19090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9931,curation_candidate,19619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9932,curation_candidate,20308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9933,curation_candidate,20385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9934,curation_candidate,20523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9935,curation_candidate,20989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9936,curation_candidate,21281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9937,curation_candidate,21506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9938,curation_candidate,21700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9939,curation_candidate,21960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9940,curation_candidate,22356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9941,curation_candidate,23426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9942,curation_candidate,23557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
9943,curation_candidate,23757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9944,curation_candidate,23776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9945,curation_candidate,23872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9946,curation_candidate,24091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9947,curation_candidate,24316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9948,curation_candidate,24561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9949,curation_candidate,24603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9950,curation_candidate,24715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9951,curation_candidate,24980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9952,curation_candidate,25049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9953,curation_candidate,25059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9954,curation_candidate,25154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9955,curation_candidate,26239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9956,curation_candidate,26368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9957,curation_candidate,26575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9958,curation_candidate,26616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9959,curation_candidate,26819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9960,curation_candidate,26825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9961,curation_candidate,26901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9962,curation_candidate,27164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9963,curation_candidate,27234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9964,curation_candidate,27419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9965,curation_candidate,27460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9966,curation_candidate,27722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9967,curation_candidate,27827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9968,curation_candidate,28421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
9969,curation_candidate,29021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9970,curation_candidate,29511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9971,curation_candidate,29843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9972,curation_candidate,30559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9973,curation_candidate,30631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9974,curation_candidate,31037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9975,curation_candidate,31319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9976,curation_candidate,31356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9977,curation_candidate,31538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9978,curation_candidate,31640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9979,curation_candidate,31685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9980,curation_candidate,32131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9981,curation_candidate,32426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9982,curation_candidate,32491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9983,curation_candidate,32927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
9984,curation_candidate,33508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9985,curation_candidate,34136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9986,curation_candidate,34466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9987,curation_candidate,35140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9988,curation_candidate,35154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9989,curation_candidate,35393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9990,curation_candidate,35713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9991,curation_candidate,36051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9992,curation_candidate,36229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9993,curation_candidate,36368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9994,curation_candidate,36496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9995,curation_candidate,36577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9996,curation_candidate,36649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9997,curation_candidate,36670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
9998,curation_candidate,36676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
9999,curation_candidate,36758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10000,curation_candidate,36872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10001,curation_candidate,36919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10002,curation_candidate,37037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10003,curation_candidate,37160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10004,curation_candidate,37185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10005,curation_candidate,37822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10006,curation_candidate,37843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10007,curation_candidate,38094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10008,curation_candidate,16391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10009,curation_candidate,16488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10010,curation_candidate,16490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10011,curation_candidate,16543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10012,curation_candidate,16588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10013,curation_candidate,16930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10014,curation_candidate,16980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10015,curation_candidate,17117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10016,curation_candidate,17119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10017,curation_candidate,17134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10018,curation_candidate,17218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10019,curation_candidate,17269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10020,curation_candidate,17278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10021,curation_candidate,17316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10022,curation_candidate,17475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10023,curation_candidate,17587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10024,curation_candidate,17731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10025,curation_candidate,18081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10026,curation_candidate,18087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10027,curation_candidate,18505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10028,curation_candidate,18508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10029,curation_candidate,18732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
10030,curation_candidate,18782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10031,curation_candidate,18802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10032,curation_candidate,19029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10033,curation_candidate,19154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
10034,curation_candidate,19490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10035,curation_candidate,20084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10036,curation_candidate,20157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10037,curation_candidate,20244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10038,curation_candidate,20265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10039,curation_candidate,20311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10040,curation_candidate,20488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10041,curation_candidate,20592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10042,curation_candidate,20660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10043,curation_candidate,20973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
10044,curation_candidate,21096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10045,curation_candidate,21193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10046,curation_candidate,21252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10047,curation_candidate,21718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10048,curation_candidate,22470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10049,curation_candidate,22569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10050,curation_candidate,22653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10051,curation_candidate,22986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10052,curation_candidate,23461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10053,curation_candidate,23491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10054,curation_candidate,23828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10055,curation_candidate,24032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10056,curation_candidate,24161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10057,curation_candidate,24314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10058,curation_candidate,24357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10059,curation_candidate,24360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10060,curation_candidate,24412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10061,curation_candidate,24455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10062,curation_candidate,24948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10063,curation_candidate,25357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10064,curation_candidate,26396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10065,curation_candidate,26519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10066,curation_candidate,26812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10067,curation_candidate,26828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10068,curation_candidate,27120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10069,curation_candidate,27136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10070,curation_candidate,27281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10071,curation_candidate,27511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10072,curation_candidate,27659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10073,curation_candidate,27711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10074,curation_candidate,27760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10075,curation_candidate,27948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10076,curation_candidate,28085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10077,curation_candidate,28130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10078,curation_candidate,28237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10079,curation_candidate,28363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10080,curation_candidate,28576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10081,curation_candidate,29034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10082,curation_candidate,29066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10083,curation_candidate,29490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10084,curation_candidate,29531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10085,curation_candidate,30102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10086,curation_candidate,30185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10087,curation_candidate,30476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10088,curation_candidate,30482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10089,curation_candidate,30883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
10090,curation_candidate,31107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
10091,curation_candidate,31178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10092,curation_candidate,31397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10093,curation_candidate,31504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10094,curation_candidate,31638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10095,curation_candidate,31824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10096,curation_candidate,32153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10097,curation_candidate,32553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10098,curation_candidate,33021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10099,curation_candidate,33083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10100,curation_candidate,33202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10101,curation_candidate,33536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10102,curation_candidate,34003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10103,curation_candidate,34004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10104,curation_candidate,34080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10105,curation_candidate,34399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10106,curation_candidate,34439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10107,curation_candidate,34644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10108,curation_candidate,34696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10109,curation_candidate,34810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10110,curation_candidate,34820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10111,curation_candidate,34881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
10112,curation_candidate,35018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10113,curation_candidate,35195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10114,curation_candidate,35475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10115,curation_candidate,35561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10116,curation_candidate,35572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10117,curation_candidate,35825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10118,curation_candidate,35885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10119,curation_candidate,35894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10120,curation_candidate,35896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10121,curation_candidate,36124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10122,curation_candidate,36227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10123,curation_candidate,36295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10124,curation_candidate,36594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10125,curation_candidate,36625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10126,curation_candidate,36929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10127,curation_candidate,36953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10128,curation_candidate,37021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10129,curation_candidate,37108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10130,curation_candidate,37378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10131,curation_candidate,37715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10132,curation_candidate,38099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10133,curation_candidate,38103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10134,curation_candidate,38138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10135,curation_candidate,16407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10136,curation_candidate,16447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
10137,curation_candidate,16452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10138,curation_candidate,16492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10139,curation_candidate,16758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10140,curation_candidate,16789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10141,curation_candidate,16854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10142,curation_candidate,16972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10143,curation_candidate,17178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10144,curation_candidate,17188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10145,curation_candidate,17203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10146,curation_candidate,17232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10147,curation_candidate,17282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10148,curation_candidate,17380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10149,curation_candidate,17415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10150,curation_candidate,17542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10151,curation_candidate,17544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10152,curation_candidate,17738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10153,curation_candidate,17942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10154,curation_candidate,18077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10155,curation_candidate,18232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10156,curation_candidate,18700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10157,curation_candidate,19061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10158,curation_candidate,19331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10159,curation_candidate,19666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10160,curation_candidate,19696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10161,curation_candidate,20477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10162,curation_candidate,20775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10163,curation_candidate,20883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10164,curation_candidate,21156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10165,curation_candidate,21228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10166,curation_candidate,21369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10167,curation_candidate,21406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10168,curation_candidate,21685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10169,curation_candidate,22132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10170,curation_candidate,22428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10171,curation_candidate,22477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10172,curation_candidate,22564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10173,curation_candidate,23313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10174,curation_candidate,23489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10175,curation_candidate,23546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10176,curation_candidate,23566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10177,curation_candidate,23686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10178,curation_candidate,23747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10179,curation_candidate,23918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10180,curation_candidate,24213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10181,curation_candidate,24244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10182,curation_candidate,24257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10183,curation_candidate,24307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10184,curation_candidate,24354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10185,curation_candidate,24787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10186,curation_candidate,25000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10187,curation_candidate,25040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10188,curation_candidate,25285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10189,curation_candidate,25367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10190,curation_candidate,25477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10191,curation_candidate,25480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10192,curation_candidate,25740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10193,curation_candidate,25810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10194,curation_candidate,25935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10195,curation_candidate,26354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10196,curation_candidate,26462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10197,curation_candidate,26494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10198,curation_candidate,26501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10199,curation_candidate,26546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10200,curation_candidate,26662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10201,curation_candidate,27336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10202,curation_candidate,28381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10203,curation_candidate,28459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10204,curation_candidate,28571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10205,curation_candidate,28975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10206,curation_candidate,29444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10207,curation_candidate,29587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10208,curation_candidate,29882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10209,curation_candidate,29975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10210,curation_candidate,30053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10211,curation_candidate,30138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10212,curation_candidate,30189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10213,curation_candidate,30722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10214,curation_candidate,30773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10215,curation_candidate,30961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10216,curation_candidate,31327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10217,curation_candidate,31343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10218,curation_candidate,31440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10219,curation_candidate,31462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10220,curation_candidate,31519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10221,curation_candidate,31559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10222,curation_candidate,31679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10223,curation_candidate,31711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10224,curation_candidate,31868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10225,curation_candidate,32162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10226,curation_candidate,32625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10227,curation_candidate,32662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10228,curation_candidate,32701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10229,curation_candidate,32706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10230,curation_candidate,32935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10231,curation_candidate,32951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10232,curation_candidate,32953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10233,curation_candidate,33177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10234,curation_candidate,33255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10235,curation_candidate,33345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10236,curation_candidate,33412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10237,curation_candidate,33686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10238,curation_candidate,33913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10239,curation_candidate,34228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10240,curation_candidate,34413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10241,curation_candidate,34698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10242,curation_candidate,35138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10243,curation_candidate,35150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10244,curation_candidate,35249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10245,curation_candidate,35259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10246,curation_candidate,35892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10247,curation_candidate,36103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10248,curation_candidate,36157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10249,curation_candidate,36297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10250,curation_candidate,36495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10251,curation_candidate,36536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10252,curation_candidate,36658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10253,curation_candidate,36806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10254,curation_candidate,36877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10255,curation_candidate,36944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10256,curation_candidate,37143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10257,curation_candidate,37218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10258,curation_candidate,37462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10259,curation_candidate,37714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10260,curation_candidate,16418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10261,curation_candidate,16643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10262,curation_candidate,17249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
10263,curation_candidate,17453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10264,curation_candidate,17565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10265,curation_candidate,17927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10266,curation_candidate,18488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10267,curation_candidate,18551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10268,curation_candidate,18759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10269,curation_candidate,19402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10270,curation_candidate,19450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10271,curation_candidate,19526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10272,curation_candidate,19607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10273,curation_candidate,20110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10274,curation_candidate,20137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10275,curation_candidate,20143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10276,curation_candidate,20389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10277,curation_candidate,20437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10278,curation_candidate,20587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10279,curation_candidate,20626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10280,curation_candidate,21007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10281,curation_candidate,21025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10282,curation_candidate,21048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10283,curation_candidate,21109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
10284,curation_candidate,21479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
10285,curation_candidate,21955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10286,curation_candidate,21987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10287,curation_candidate,22048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10288,curation_candidate,22156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10289,curation_candidate,22178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10290,curation_candidate,22219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10291,curation_candidate,22245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10292,curation_candidate,22382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10293,curation_candidate,22447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10294,curation_candidate,22764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10295,curation_candidate,23948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10296,curation_candidate,24001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10297,curation_candidate,24221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10298,curation_candidate,25159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10299,curation_candidate,25406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10300,curation_candidate,26015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10301,curation_candidate,26436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10302,curation_candidate,27219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10303,curation_candidate,27253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10304,curation_candidate,27643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10305,curation_candidate,27987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10306,curation_candidate,28014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10307,curation_candidate,28775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10308,curation_candidate,29398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10309,curation_candidate,29814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10310,curation_candidate,30004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10311,curation_candidate,30036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10312,curation_candidate,30061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10313,curation_candidate,30070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10314,curation_candidate,30193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10315,curation_candidate,30260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10316,curation_candidate,30269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10317,curation_candidate,30698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10318,curation_candidate,31366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10319,curation_candidate,31395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10320,curation_candidate,31721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10321,curation_candidate,31779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10322,curation_candidate,31830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10323,curation_candidate,31865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10324,curation_candidate,32123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10325,curation_candidate,32168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10326,curation_candidate,32838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10327,curation_candidate,32991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10328,curation_candidate,33091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10329,curation_candidate,33222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10330,curation_candidate,33224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10331,curation_candidate,33280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10332,curation_candidate,33811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10333,curation_candidate,34191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10334,curation_candidate,34223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10335,curation_candidate,34344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10336,curation_candidate,34870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10337,curation_candidate,35205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10338,curation_candidate,35487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10339,curation_candidate,36110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10340,curation_candidate,36151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10341,curation_candidate,36636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10342,curation_candidate,37026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10343,curation_candidate,16402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
10344,curation_candidate,16459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
10345,curation_candidate,16473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10346,curation_candidate,16535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10347,curation_candidate,16555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10348,curation_candidate,16699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10349,curation_candidate,16922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10350,curation_candidate,17112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10351,curation_candidate,17504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10352,curation_candidate,17627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10353,curation_candidate,17640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10354,curation_candidate,17658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10355,curation_candidate,17899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10356,curation_candidate,18013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10357,curation_candidate,18043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10358,curation_candidate,18211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10359,curation_candidate,18278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10360,curation_candidate,18374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10361,curation_candidate,18675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10362,curation_candidate,18723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10363,curation_candidate,19210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10364,curation_candidate,19695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10365,curation_candidate,21222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10366,curation_candidate,21687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10367,curation_candidate,21927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10368,curation_candidate,22509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10369,curation_candidate,22955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10370,curation_candidate,23520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10371,curation_candidate,23623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10372,curation_candidate,24243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10373,curation_candidate,24513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10374,curation_candidate,24945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10375,curation_candidate,25355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10376,curation_candidate,25479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10377,curation_candidate,25507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10378,curation_candidate,26340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10379,curation_candidate,27257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10380,curation_candidate,27482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10381,curation_candidate,27590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10382,curation_candidate,28269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10383,curation_candidate,29125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10384,curation_candidate,30729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10385,curation_candidate,31017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10386,curation_candidate,31105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10387,curation_candidate,31665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10388,curation_candidate,31909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10389,curation_candidate,32722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10390,curation_candidate,33167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10391,curation_candidate,33190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10392,curation_candidate,33191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10393,curation_candidate,33420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10394,curation_candidate,33612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10395,curation_candidate,33973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10396,curation_candidate,34701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10397,curation_candidate,35788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10398,curation_candidate,36356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
10399,curation_candidate,36484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10400,curation_candidate,36626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10401,curation_candidate,36948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10402,curation_candidate,38036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
10403,curation_candidate,16421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
10404,curation_candidate,16436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10405,curation_candidate,16474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10406,curation_candidate,16560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10407,curation_candidate,16600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10408,curation_candidate,17075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10409,curation_candidate,17503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10410,curation_candidate,17998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10411,curation_candidate,18022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
10412,curation_candidate,18576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10413,curation_candidate,18588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10414,curation_candidate,18879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10415,curation_candidate,18960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10416,curation_candidate,19125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10417,curation_candidate,19977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10418,curation_candidate,20383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10419,curation_candidate,20620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10420,curation_candidate,20736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10421,curation_candidate,21290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10422,curation_candidate,21308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10423,curation_candidate,21522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10424,curation_candidate,21572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10425,curation_candidate,22393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10426,curation_candidate,22645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10427,curation_candidate,22711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10428,curation_candidate,22814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10429,curation_candidate,23142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10430,curation_candidate,23266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10431,curation_candidate,23306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10432,curation_candidate,23369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10433,curation_candidate,23540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10434,curation_candidate,24229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10435,curation_candidate,24539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10436,curation_candidate,24721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10437,curation_candidate,25570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10438,curation_candidate,25724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10439,curation_candidate,26036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10440,curation_candidate,26599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10441,curation_candidate,26796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10442,curation_candidate,27148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10443,curation_candidate,27186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10444,curation_candidate,27552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10445,curation_candidate,28076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10446,curation_candidate,28909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10447,curation_candidate,29017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10448,curation_candidate,29850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10449,curation_candidate,30207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10450,curation_candidate,30474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10451,curation_candidate,30598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10452,curation_candidate,30747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10453,curation_candidate,30971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10454,curation_candidate,31137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10455,curation_candidate,31431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10456,curation_candidate,31576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10457,curation_candidate,31586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10458,curation_candidate,32056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10459,curation_candidate,32333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10460,curation_candidate,32533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10461,curation_candidate,33010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10462,curation_candidate,33115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10463,curation_candidate,33169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10464,curation_candidate,33277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10465,curation_candidate,33601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10466,curation_candidate,33687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10467,curation_candidate,33723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10468,curation_candidate,34085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10469,curation_candidate,34537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10470,curation_candidate,34933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10471,curation_candidate,35147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10472,curation_candidate,35297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10473,curation_candidate,35328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10474,curation_candidate,35343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10475,curation_candidate,35445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10476,curation_candidate,35657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10477,curation_candidate,35899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10478,curation_candidate,36611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10479,curation_candidate,37175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10480,curation_candidate,37607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10481,curation_candidate,37842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10482,curation_candidate,38209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10483,curation_candidate,16434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10484,curation_candidate,16471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
10485,curation_candidate,16706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10486,curation_candidate,18238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10487,curation_candidate,18490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10488,curation_candidate,18673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10489,curation_candidate,19045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10490,curation_candidate,19171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10491,curation_candidate,20767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10492,curation_candidate,20846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10493,curation_candidate,20981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10494,curation_candidate,21652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10495,curation_candidate,22140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10496,curation_candidate,22152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10497,curation_candidate,22378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10498,curation_candidate,22641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10499,curation_candidate,22880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10500,curation_candidate,22907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10501,curation_candidate,23370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10502,curation_candidate,23573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10503,curation_candidate,24778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10504,curation_candidate,24910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10505,curation_candidate,24966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10506,curation_candidate,25147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10507,curation_candidate,25508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10508,curation_candidate,26739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10509,curation_candidate,27298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10510,curation_candidate,27495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10511,curation_candidate,28402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10512,curation_candidate,29329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10513,curation_candidate,29931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10514,curation_candidate,30039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10515,curation_candidate,30253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10516,curation_candidate,30264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10517,curation_candidate,30368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10518,curation_candidate,30610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10519,curation_candidate,30860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10520,curation_candidate,30870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10521,curation_candidate,31390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10522,curation_candidate,31502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10523,curation_candidate,31539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10524,curation_candidate,32062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10525,curation_candidate,32614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10526,curation_candidate,32718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10527,curation_candidate,32877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10528,curation_candidate,32996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10529,curation_candidate,33093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10530,curation_candidate,33131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10531,curation_candidate,33270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10532,curation_candidate,33562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10533,curation_candidate,33960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10534,curation_candidate,34388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10535,curation_candidate,34538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10536,curation_candidate,34823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10537,curation_candidate,35093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10538,curation_candidate,35268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10539,curation_candidate,36226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10540,curation_candidate,36243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10541,curation_candidate,37606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10542,curation_candidate,37876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10543,curation_candidate,16363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10544,curation_candidate,16392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
10545,curation_candidate,16900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10546,curation_candidate,16947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10547,curation_candidate,18305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10548,curation_candidate,18369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10549,curation_candidate,19184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10550,curation_candidate,19786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10551,curation_candidate,20684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10552,curation_candidate,21843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10553,curation_candidate,22231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10554,curation_candidate,22236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10555,curation_candidate,23440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10556,curation_candidate,23543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10557,curation_candidate,24556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10558,curation_candidate,25644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10559,curation_candidate,26591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10560,curation_candidate,26692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10561,curation_candidate,27342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10562,curation_candidate,27929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10563,curation_candidate,28359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10564,curation_candidate,28631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10565,curation_candidate,30047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10566,curation_candidate,30125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10567,curation_candidate,30567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10568,curation_candidate,30804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10569,curation_candidate,30908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10570,curation_candidate,30937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10571,curation_candidate,31069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10572,curation_candidate,31271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10573,curation_candidate,31334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10574,curation_candidate,31532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10575,curation_candidate,32171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10576,curation_candidate,32414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10577,curation_candidate,32452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10578,curation_candidate,33016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10579,curation_candidate,33125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10580,curation_candidate,33267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10581,curation_candidate,33778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10582,curation_candidate,35556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10583,curation_candidate,35797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10584,curation_candidate,36135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10585,curation_candidate,36250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10586,curation_candidate,36779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10587,curation_candidate,37852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10588,curation_candidate,16356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10589,curation_candidate,16561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10590,curation_candidate,16573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10591,curation_candidate,16976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10592,curation_candidate,17147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10593,curation_candidate,17351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10594,curation_candidate,17353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10595,curation_candidate,17527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10596,curation_candidate,17780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10597,curation_candidate,17911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10598,curation_candidate,18008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10599,curation_candidate,18559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10600,curation_candidate,19428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10601,curation_candidate,20245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10602,curation_candidate,20702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10603,curation_candidate,20791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
10604,curation_candidate,21132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10605,curation_candidate,21750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10606,curation_candidate,21979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10607,curation_candidate,22332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10608,curation_candidate,23016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10609,curation_candidate,23334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10610,curation_candidate,23379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10611,curation_candidate,23415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10612,curation_candidate,23615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10613,curation_candidate,24938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10614,curation_candidate,25265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10615,curation_candidate,26958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10616,curation_candidate,28018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10617,curation_candidate,28510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10618,curation_candidate,29796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10619,curation_candidate,29866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10620,curation_candidate,29952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10621,curation_candidate,29972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10622,curation_candidate,30087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10623,curation_candidate,30090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10624,curation_candidate,30104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10625,curation_candidate,30105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10626,curation_candidate,30135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10627,curation_candidate,30149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10628,curation_candidate,30173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10629,curation_candidate,30198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10630,curation_candidate,30534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10631,curation_candidate,30683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10632,curation_candidate,30764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10633,curation_candidate,30795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10634,curation_candidate,31066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10635,curation_candidate,31767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10636,curation_candidate,31990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10637,curation_candidate,32003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10638,curation_candidate,32931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10639,curation_candidate,32997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10640,curation_candidate,33025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10641,curation_candidate,33116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10642,curation_candidate,33172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10643,curation_candidate,33590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10644,curation_candidate,33657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10645,curation_candidate,33717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10646,curation_candidate,34307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10647,curation_candidate,34534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10648,curation_candidate,34687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10649,curation_candidate,34981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10650,curation_candidate,35066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10651,curation_candidate,35237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10652,curation_candidate,35830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10653,curation_candidate,35831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10654,curation_candidate,36118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
10655,curation_candidate,36345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10656,curation_candidate,36535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10657,curation_candidate,37101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10658,curation_candidate,37236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10659,curation_candidate,37819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10660,curation_candidate,38107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10661,curation_candidate,16806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10662,curation_candidate,16953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10663,curation_candidate,16991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10664,curation_candidate,17230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10665,curation_candidate,17376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10666,curation_candidate,17562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
10667,curation_candidate,17580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10668,curation_candidate,17635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10669,curation_candidate,17677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10670,curation_candidate,17682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10671,curation_candidate,18432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10672,curation_candidate,18435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10673,curation_candidate,18687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10674,curation_candidate,19315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10675,curation_candidate,19486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10676,curation_candidate,21446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10677,curation_candidate,21884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10678,curation_candidate,22068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10679,curation_candidate,22143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10680,curation_candidate,22389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10681,curation_candidate,22859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10682,curation_candidate,23180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10683,curation_candidate,23323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10684,curation_candidate,23939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10685,curation_candidate,24299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10686,curation_candidate,24421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10687,curation_candidate,25291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10688,curation_candidate,25636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10689,curation_candidate,26962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10690,curation_candidate,29856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10691,curation_candidate,30071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10692,curation_candidate,30082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10693,curation_candidate,30240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10694,curation_candidate,30298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10695,curation_candidate,30319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10696,curation_candidate,30409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10697,curation_candidate,30833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10698,curation_candidate,31060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10699,curation_candidate,31140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10700,curation_candidate,31389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10701,curation_candidate,31406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10702,curation_candidate,31733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10703,curation_candidate,32095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10704,curation_candidate,32384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10705,curation_candidate,32640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10706,curation_candidate,32665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10707,curation_candidate,34565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10708,curation_candidate,35378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10709,curation_candidate,35381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10710,curation_candidate,35903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10711,curation_candidate,35919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10712,curation_candidate,36604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10713,curation_candidate,36837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10714,curation_candidate,36972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10715,curation_candidate,37132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10716,curation_candidate,38254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10717,curation_candidate,38309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10718,curation_candidate,16504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10719,curation_candidate,16569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10720,curation_candidate,16919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10721,curation_candidate,18111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10722,curation_candidate,18213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10723,curation_candidate,18327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10724,curation_candidate,18592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10725,curation_candidate,19243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10726,curation_candidate,22024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10727,curation_candidate,22772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10728,curation_candidate,22984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10729,curation_candidate,23651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10730,curation_candidate,24207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10731,curation_candidate,24692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10732,curation_candidate,25200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10733,curation_candidate,29916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10734,curation_candidate,30007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10735,curation_candidate,30063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10736,curation_candidate,30146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10737,curation_candidate,30592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10738,curation_candidate,30673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10739,curation_candidate,30726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10740,curation_candidate,31002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10741,curation_candidate,31393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10742,curation_candidate,31438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10743,curation_candidate,31564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10744,curation_candidate,31905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10745,curation_candidate,32086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10746,curation_candidate,32442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10747,curation_candidate,32590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10748,curation_candidate,32765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10749,curation_candidate,32899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10750,curation_candidate,34272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10751,curation_candidate,34330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10752,curation_candidate,34451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10753,curation_candidate,35377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10754,curation_candidate,35754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10755,curation_candidate,36277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10756,curation_candidate,36385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10757,curation_candidate,36412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10758,curation_candidate,36818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10759,curation_candidate,38120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10760,curation_candidate,20338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10761,curation_candidate,20577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10762,curation_candidate,22446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10763,curation_candidate,29782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
10764,curation_candidate,30093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10765,curation_candidate,30226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10766,curation_candidate,31127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10767,curation_candidate,31479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
10768,curation_candidate,31871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10769,curation_candidate,32026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10770,curation_candidate,32189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10771,curation_candidate,32369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10772,curation_candidate,32995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10773,curation_candidate,33233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10774,curation_candidate,33311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10775,curation_candidate,33434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10776,curation_candidate,33691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10777,curation_candidate,33934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10778,curation_candidate,34116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10779,curation_candidate,34511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10780,curation_candidate,34531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10781,curation_candidate,34945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10782,curation_candidate,35382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10783,curation_candidate,36224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10784,curation_candidate,36557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10785,curation_candidate,36656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10786,curation_candidate,38188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10787,curation_candidate,29995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10788,curation_candidate,30181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10789,curation_candidate,30234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10790,curation_candidate,30283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10791,curation_candidate,30638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10792,curation_candidate,31143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10793,curation_candidate,31674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10794,curation_candidate,31903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10795,curation_candidate,32305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10796,curation_candidate,32394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10797,curation_candidate,32407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10798,curation_candidate,32415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10799,curation_candidate,32796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10800,curation_candidate,32979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10801,curation_candidate,32982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10802,curation_candidate,32998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10803,curation_candidate,33188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10804,curation_candidate,33208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10805,curation_candidate,33659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10806,curation_candidate,35309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10807,curation_candidate,36905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10808,curation_candidate,36911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10809,curation_candidate,37031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10810,curation_candidate,37142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10811,curation_candidate,37221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10812,curation_candidate,30413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10813,curation_candidate,30419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10814,curation_candidate,30438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10815,curation_candidate,33055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10816,curation_candidate,33063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10817,curation_candidate,33268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10818,curation_candidate,33609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10819,curation_candidate,33979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10820,curation_candidate,34345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10821,curation_candidate,35241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10822,curation_candidate,36002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10823,curation_candidate,36057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10824,curation_candidate,36803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10825,curation_candidate,37146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10826,curation_candidate,37300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10827,curation_candidate,30118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10828,curation_candidate,30459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10829,curation_candidate,31853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10830,curation_candidate,32340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10831,curation_candidate,33133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10832,curation_candidate,35001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10833,curation_candidate,30695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10834,curation_candidate,32276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10835,curation_candidate,32298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10836,curation_candidate,32453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10837,curation_candidate,32797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10838,curation_candidate,32813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10839,curation_candidate,33027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10840,curation_candidate,35918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10841,curation_candidate,36029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10842,curation_candidate,36464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10843,curation_candidate,37182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10844,curation_candidate,37399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10845,curation_candidate,31896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10846,curation_candidate,33139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10847,curation_candidate,35611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10848,curation_candidate,36038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10849,curation_candidate,36104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10850,curation_candidate,36737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10851,curation_candidate,13725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10852,curation_candidate,13735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10853,curation_candidate,13736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10854,curation_candidate,13741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10855,curation_candidate,13744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10856,curation_candidate,13747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10857,curation_candidate,13749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10858,curation_candidate,13751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10859,curation_candidate,13755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10860,curation_candidate,13761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10861,curation_candidate,13767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10862,curation_candidate,13769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10863,curation_candidate,13774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10864,curation_candidate,13775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10865,curation_candidate,13779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10866,curation_candidate,13784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10867,curation_candidate,13788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10868,curation_candidate,13791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10869,curation_candidate,13792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10870,curation_candidate,13794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10871,curation_candidate,13797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10872,curation_candidate,13813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10873,curation_candidate,13818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10874,curation_candidate,13838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10875,curation_candidate,13840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10876,curation_candidate,13842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10877,curation_candidate,13845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10878,curation_candidate,13849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10879,curation_candidate,13854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10880,curation_candidate,13857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10881,curation_candidate,13859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10882,curation_candidate,13885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10883,curation_candidate,13887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10884,curation_candidate,13900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10885,curation_candidate,13904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10886,curation_candidate,13906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10887,curation_candidate,13907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10888,curation_candidate,13909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10889,curation_candidate,13910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10890,curation_candidate,13915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10891,curation_candidate,13917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10892,curation_candidate,13919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10893,curation_candidate,13920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10894,curation_candidate,13922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10895,curation_candidate,13923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10896,curation_candidate,13932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10897,curation_candidate,13934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10898,curation_candidate,13941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10899,curation_candidate,13942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10900,curation_candidate,13950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10901,curation_candidate,13951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10902,curation_candidate,13952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10903,curation_candidate,13958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10904,curation_candidate,13964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10905,curation_candidate,13966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10906,curation_candidate,13973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10907,curation_candidate,13983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10908,curation_candidate,13990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10909,curation_candidate,13991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10910,curation_candidate,13993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10911,curation_candidate,13995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10912,curation_candidate,13999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10913,curation_candidate,14001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10914,curation_candidate,14006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10915,curation_candidate,14012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10916,curation_candidate,14014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10917,curation_candidate,14021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10918,curation_candidate,14024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10919,curation_candidate,14027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10920,curation_candidate,14030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10921,curation_candidate,14032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10922,curation_candidate,14042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10923,curation_candidate,14046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10924,curation_candidate,14047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10925,curation_candidate,14052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10926,curation_candidate,14053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10927,curation_candidate,14064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10928,curation_candidate,14066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10929,curation_candidate,14071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10930,curation_candidate,14072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10931,curation_candidate,14080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10932,curation_candidate,14082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10933,curation_candidate,14106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10934,curation_candidate,14109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10935,curation_candidate,14110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10936,curation_candidate,14124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10937,curation_candidate,14130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10938,curation_candidate,14136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10939,curation_candidate,14138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10940,curation_candidate,14142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10941,curation_candidate,14146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10942,curation_candidate,14148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10943,curation_candidate,14150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10944,curation_candidate,14153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10945,curation_candidate,14160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10946,curation_candidate,14165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10947,curation_candidate,14176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10948,curation_candidate,14184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10949,curation_candidate,14197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
10950,curation_candidate,14202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10951,curation_candidate,14208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10952,curation_candidate,14210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10953,curation_candidate,14216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10954,curation_candidate,14218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10955,curation_candidate,14221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10956,curation_candidate,14225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10957,curation_candidate,14235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10958,curation_candidate,14247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10959,curation_candidate,14248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10960,curation_candidate,14252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10961,curation_candidate,14259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10962,curation_candidate,14261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10963,curation_candidate,14263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10964,curation_candidate,14265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10965,curation_candidate,14282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10966,curation_candidate,14285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10967,curation_candidate,14288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10968,curation_candidate,14289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10969,curation_candidate,14292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10970,curation_candidate,14294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10971,curation_candidate,14296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10972,curation_candidate,14306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10973,curation_candidate,14316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10974,curation_candidate,14338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10975,curation_candidate,14343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10976,curation_candidate,14354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10977,curation_candidate,14358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10978,curation_candidate,14359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10979,curation_candidate,14361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10980,curation_candidate,14371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10981,curation_candidate,14373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10982,curation_candidate,14377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10983,curation_candidate,14381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10984,curation_candidate,14392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10985,curation_candidate,14395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10986,curation_candidate,14405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10987,curation_candidate,14413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10988,curation_candidate,14415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10989,curation_candidate,14416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10990,curation_candidate,14417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
10991,curation_candidate,14428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10992,curation_candidate,15090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10993,curation_candidate,15101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10994,curation_candidate,15128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10995,curation_candidate,15129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
10996,curation_candidate,15153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
10997,curation_candidate,15155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10998,curation_candidate,15156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
10999,curation_candidate,15159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11000,curation_candidate,15161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11001,curation_candidate,15162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11002,curation_candidate,15166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11003,curation_candidate,15169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11004,curation_candidate,15170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11005,curation_candidate,15173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11006,curation_candidate,15175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11007,curation_candidate,15176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11008,curation_candidate,15177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11009,curation_candidate,15180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11010,curation_candidate,15181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11011,curation_candidate,15182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11012,curation_candidate,15184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11013,curation_candidate,15185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11014,curation_candidate,15393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11015,curation_candidate,15403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11016,curation_candidate,15405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11017,curation_candidate,15411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11018,curation_candidate,15420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11019,curation_candidate,15427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11020,curation_candidate,15430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11021,curation_candidate,15437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11022,curation_candidate,15443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11023,curation_candidate,15445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11024,curation_candidate,15450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11025,curation_candidate,15452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11026,curation_candidate,15458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11027,curation_candidate,15460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11028,curation_candidate,15467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11029,curation_candidate,15470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11030,curation_candidate,15471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11031,curation_candidate,15472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11032,curation_candidate,15477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11033,curation_candidate,15481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11034,curation_candidate,15484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11035,curation_candidate,15487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11036,curation_candidate,15489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11037,curation_candidate,15491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11038,curation_candidate,15494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11039,curation_candidate,15499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11040,curation_candidate,15502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11041,curation_candidate,15511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11042,curation_candidate,15512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11043,curation_candidate,15514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11044,curation_candidate,15515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11045,curation_candidate,15521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11046,curation_candidate,15522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11047,curation_candidate,15525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11048,curation_candidate,15529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11049,curation_candidate,15530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11050,curation_candidate,15532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11051,curation_candidate,15535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11052,curation_candidate,15537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11053,curation_candidate,15543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11054,curation_candidate,15545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11055,curation_candidate,15549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11056,curation_candidate,15551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11057,curation_candidate,15552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11058,curation_candidate,15553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11059,curation_candidate,15555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11060,curation_candidate,15561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11061,curation_candidate,15565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11062,curation_candidate,15567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11063,curation_candidate,15568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11064,curation_candidate,15570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11065,curation_candidate,15574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11066,curation_candidate,15576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11067,curation_candidate,15577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11068,curation_candidate,15579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11069,curation_candidate,15586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11070,curation_candidate,15587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11071,curation_candidate,15589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11072,curation_candidate,15593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11073,curation_candidate,15597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11074,curation_candidate,15598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11075,curation_candidate,15600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11076,curation_candidate,15606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11077,curation_candidate,15609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11078,curation_candidate,15610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11079,curation_candidate,15615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11080,curation_candidate,15617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11081,curation_candidate,15618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11082,curation_candidate,15627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11083,curation_candidate,18476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11084,curation_candidate,19349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11085,curation_candidate,20716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11086,curation_candidate,20735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11087,curation_candidate,21332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11088,curation_candidate,23317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11089,curation_candidate,24105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11090,curation_candidate,24211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11091,curation_candidate,24400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11092,curation_candidate,30262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11093,curation_candidate,30881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11094,curation_candidate,30988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11095,curation_candidate,31121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11096,curation_candidate,31587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11097,curation_candidate,32039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11098,curation_candidate,32909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11099,curation_candidate,36609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11100,curation_candidate,36766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11101,curation_candidate,37342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11102,curation_candidate,10311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11103,curation_candidate,10320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11104,curation_candidate,10328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11105,curation_candidate,10361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11106,curation_candidate,10563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11107,curation_candidate,10567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11108,curation_candidate,10741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11109,curation_candidate,10744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11110,curation_candidate,10755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11111,curation_candidate,10768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11112,curation_candidate,10770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11113,curation_candidate,10877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11114,curation_candidate,10983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11115,curation_candidate,10988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11116,curation_candidate,10994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11117,curation_candidate,11003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11118,curation_candidate,11480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11119,curation_candidate,11483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11120,curation_candidate,11491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11121,curation_candidate,11498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11122,curation_candidate,11500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11123,curation_candidate,11503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11124,curation_candidate,11509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11125,curation_candidate,11511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11126,curation_candidate,11514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11127,curation_candidate,11515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11128,curation_candidate,11517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11129,curation_candidate,11518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11130,curation_candidate,11524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11131,curation_candidate,11531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11132,curation_candidate,11534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11133,curation_candidate,11536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11134,curation_candidate,11538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11135,curation_candidate,11543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11136,curation_candidate,11546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11137,curation_candidate,11547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11138,curation_candidate,11550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11139,curation_candidate,11551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11140,curation_candidate,11552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11141,curation_candidate,11553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11142,curation_candidate,11559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11143,curation_candidate,14459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11144,curation_candidate,14468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11145,curation_candidate,14478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11146,curation_candidate,14483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11147,curation_candidate,14484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11148,curation_candidate,14487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11149,curation_candidate,14489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11150,curation_candidate,14498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11151,curation_candidate,14505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11152,curation_candidate,14507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11153,curation_candidate,14519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11154,curation_candidate,14521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11155,curation_candidate,14522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11156,curation_candidate,14532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11157,curation_candidate,14541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11158,curation_candidate,14542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11159,curation_candidate,14549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11160,curation_candidate,14551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11161,curation_candidate,14563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11162,curation_candidate,14565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11163,curation_candidate,14585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11164,curation_candidate,14589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11165,curation_candidate,14594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11166,curation_candidate,14598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11167,curation_candidate,14602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11168,curation_candidate,14607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11169,curation_candidate,14611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11170,curation_candidate,14613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11171,curation_candidate,14614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11172,curation_candidate,14621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11173,curation_candidate,14625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11174,curation_candidate,14630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11175,curation_candidate,14636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11176,curation_candidate,14638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11177,curation_candidate,14671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11178,curation_candidate,14673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11179,curation_candidate,14675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11180,curation_candidate,14699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11181,curation_candidate,14703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11182,curation_candidate,14707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11183,curation_candidate,14715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11184,curation_candidate,14718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11185,curation_candidate,14743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11186,curation_candidate,14745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
11187,curation_candidate,14747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11188,curation_candidate,14748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11189,curation_candidate,14751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11190,curation_candidate,14753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11191,curation_candidate,14754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11192,curation_candidate,14757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11193,curation_candidate,14758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11194,curation_candidate,14762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11195,curation_candidate,14770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11196,curation_candidate,14771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11197,curation_candidate,14772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11198,curation_candidate,14775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11199,curation_candidate,14776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11200,curation_candidate,14786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11201,curation_candidate,14788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11202,curation_candidate,14789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11203,curation_candidate,14792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11204,curation_candidate,14794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11205,curation_candidate,14798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11206,curation_candidate,14801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11207,curation_candidate,14812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11208,curation_candidate,14813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11209,curation_candidate,14815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11210,curation_candidate,14816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11211,curation_candidate,14818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11212,curation_candidate,14821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11213,curation_candidate,14828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11214,curation_candidate,14829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11215,curation_candidate,14836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11216,curation_candidate,14838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11217,curation_candidate,14839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11218,curation_candidate,14840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11219,curation_candidate,14843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11220,curation_candidate,14852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11221,curation_candidate,14856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11222,curation_candidate,14859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11223,curation_candidate,14875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11224,curation_candidate,14881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11225,curation_candidate,14882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11226,curation_candidate,14884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11227,curation_candidate,14887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11228,curation_candidate,14897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11229,curation_candidate,14900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11230,curation_candidate,14902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11231,curation_candidate,14910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11232,curation_candidate,14911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11233,curation_candidate,14912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11234,curation_candidate,14914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11235,curation_candidate,14915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11236,curation_candidate,14916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11237,curation_candidate,14920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11238,curation_candidate,14923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11239,curation_candidate,14925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11240,curation_candidate,14930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11241,curation_candidate,14931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11242,curation_candidate,14933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11243,curation_candidate,14934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11244,curation_candidate,14937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11245,curation_candidate,14942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11246,curation_candidate,14944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11247,curation_candidate,14948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11248,curation_candidate,15092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11249,curation_candidate,15104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11250,curation_candidate,15194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11251,curation_candidate,15198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11252,curation_candidate,15199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11253,curation_candidate,15202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11254,curation_candidate,15203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11255,curation_candidate,15204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11256,curation_candidate,15208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11257,curation_candidate,15215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11258,curation_candidate,15221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11259,curation_candidate,15633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11260,curation_candidate,15638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11261,curation_candidate,15644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11262,curation_candidate,15655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11263,curation_candidate,15656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11264,curation_candidate,15657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11265,curation_candidate,15660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11266,curation_candidate,15678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11267,curation_candidate,15680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11268,curation_candidate,15684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11269,curation_candidate,15685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11270,curation_candidate,15689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11271,curation_candidate,15700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11272,curation_candidate,15703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11273,curation_candidate,15705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
11274,curation_candidate,15709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11275,curation_candidate,15713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11276,curation_candidate,15723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11277,curation_candidate,16352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11278,curation_candidate,16540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11279,curation_candidate,17709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11280,curation_candidate,17729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11281,curation_candidate,17924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11282,curation_candidate,18031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11283,curation_candidate,18047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11284,curation_candidate,19922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11285,curation_candidate,20299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11286,curation_candidate,20933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11287,curation_candidate,21345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11288,curation_candidate,21570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11289,curation_candidate,21879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11290,curation_candidate,23721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11291,curation_candidate,25370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11292,curation_candidate,26611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11293,curation_candidate,27056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11294,curation_candidate,27301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11295,curation_candidate,27397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11296,curation_candidate,27475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11297,curation_candidate,28688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11298,curation_candidate,30892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11299,curation_candidate,31716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11300,curation_candidate,31856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
11301,curation_candidate,31988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11302,curation_candidate,33491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11303,curation_candidate,36408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11304,curation_candidate,10381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11305,curation_candidate,10576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11306,curation_candidate,10780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11307,curation_candidate,11006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11308,curation_candidate,11014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11309,curation_candidate,11015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11310,curation_candidate,11119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11311,curation_candidate,11568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11312,curation_candidate,14979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
11313,curation_candidate,14984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
11314,curation_candidate,14988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11315,curation_candidate,14989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11316,curation_candidate,14990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11317,curation_candidate,14993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11318,curation_candidate,14999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11319,curation_candidate,15008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11320,curation_candidate,15017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11321,curation_candidate,15026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11322,curation_candidate,15027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11323,curation_candidate,15029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11324,curation_candidate,15031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11325,curation_candidate,15032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11326,curation_candidate,15035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11327,curation_candidate,15037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11328,curation_candidate,15040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11329,curation_candidate,15047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11330,curation_candidate,15052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11331,curation_candidate,15055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11332,curation_candidate,15057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11333,curation_candidate,15064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11334,curation_candidate,15065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11335,curation_candidate,15066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11336,curation_candidate,15075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11337,curation_candidate,15076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11338,curation_candidate,15081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11339,curation_candidate,15764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11340,curation_candidate,15769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11341,curation_candidate,15774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11342,curation_candidate,15796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11343,curation_candidate,15800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11344,curation_candidate,15804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11345,curation_candidate,15818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11346,curation_candidate,15827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11347,curation_candidate,15828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11348,curation_candidate,15832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11349,curation_candidate,15835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
11350,curation_candidate,15838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11351,curation_candidate,15839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11352,curation_candidate,15850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11353,curation_candidate,15854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11354,curation_candidate,15856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11355,curation_candidate,15860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11356,curation_candidate,15867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11357,curation_candidate,15870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11358,curation_candidate,15873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11359,curation_candidate,15875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11360,curation_candidate,15883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11361,curation_candidate,15891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11362,curation_candidate,15898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11363,curation_candidate,15901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11364,curation_candidate,15906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
11365,curation_candidate,15907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11366,curation_candidate,15909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11367,curation_candidate,15915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
11368,curation_candidate,15920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11369,curation_candidate,15925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11370,curation_candidate,15933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11371,curation_candidate,15935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11372,curation_candidate,15939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11373,curation_candidate,15941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11374,curation_candidate,15942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11375,curation_candidate,15943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11376,curation_candidate,16374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11377,curation_candidate,16844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11378,curation_candidate,17148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11379,curation_candidate,17357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11380,curation_candidate,17920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11381,curation_candidate,19010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11382,curation_candidate,19047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11383,curation_candidate,19101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11384,curation_candidate,19554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11385,curation_candidate,19847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11386,curation_candidate,19929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11387,curation_candidate,20231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11388,curation_candidate,20306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11389,curation_candidate,21095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11390,curation_candidate,21098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11391,curation_candidate,21243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11392,curation_candidate,21929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11393,curation_candidate,22237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11394,curation_candidate,24352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11395,curation_candidate,24962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11396,curation_candidate,25162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11397,curation_candidate,25598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11398,curation_candidate,28175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11399,curation_candidate,28553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11400,curation_candidate,29774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11401,curation_candidate,30920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11402,curation_candidate,30954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11403,curation_candidate,32968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11404,curation_candidate,35729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11405,curation_candidate,36311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11406,curation_candidate,36961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11407,curation_candidate,37382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11408,curation_candidate,37845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11409,curation_candidate,10804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11410,curation_candidate,10805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11411,curation_candidate,11028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11412,curation_candidate,11125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11413,curation_candidate,11612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
11414,curation_candidate,11618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
11415,curation_candidate,11625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11416,curation_candidate,11634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11417,curation_candidate,11763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11418,curation_candidate,15950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11419,curation_candidate,15963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11420,curation_candidate,15967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11421,curation_candidate,15984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11422,curation_candidate,15986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11423,curation_candidate,15990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11424,curation_candidate,15992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11425,curation_candidate,16000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11426,curation_candidate,16020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11427,curation_candidate,16025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11428,curation_candidate,16031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11429,curation_candidate,16044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11430,curation_candidate,16056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11431,curation_candidate,16058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11432,curation_candidate,16066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11433,curation_candidate,16506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11434,curation_candidate,16870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11435,curation_candidate,17165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11436,curation_candidate,17323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11437,curation_candidate,17698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11438,curation_candidate,17817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11439,curation_candidate,19199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11440,curation_candidate,19289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11441,curation_candidate,19659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11442,curation_candidate,19746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11443,curation_candidate,20310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11444,curation_candidate,20542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11445,curation_candidate,20567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11446,curation_candidate,20573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11447,curation_candidate,21571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11448,curation_candidate,21789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11449,curation_candidate,22724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11450,curation_candidate,23758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11451,curation_candidate,23940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11452,curation_candidate,25460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11453,curation_candidate,26339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11454,curation_candidate,27116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11455,curation_candidate,27248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11456,curation_candidate,27754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11457,curation_candidate,28166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11458,curation_candidate,28906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11459,curation_candidate,28931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11460,curation_candidate,29012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11461,curation_candidate,29837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11462,curation_candidate,30925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11463,curation_candidate,34281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11464,curation_candidate,35215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11465,curation_candidate,36904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11466,curation_candidate,10517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11467,curation_candidate,10518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11468,curation_candidate,10904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11469,curation_candidate,11035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11470,curation_candidate,11038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
11471,curation_candidate,11041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11472,curation_candidate,11042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11473,curation_candidate,11650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11474,curation_candidate,11651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11475,curation_candidate,11652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11476,curation_candidate,11660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11477,curation_candidate,11663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11478,curation_candidate,11666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11479,curation_candidate,11667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11480,curation_candidate,11668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11481,curation_candidate,11669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11482,curation_candidate,15094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11483,curation_candidate,15115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11484,curation_candidate,15240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11485,curation_candidate,15241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11486,curation_candidate,15243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11487,curation_candidate,16090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11488,curation_candidate,16102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11489,curation_candidate,16104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11490,curation_candidate,16107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11491,curation_candidate,16115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11492,curation_candidate,16116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11493,curation_candidate,16125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11494,curation_candidate,16128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11495,curation_candidate,16142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11496,curation_candidate,16144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11497,curation_candidate,16145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11498,curation_candidate,16147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11499,curation_candidate,16148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
11500,curation_candidate,16171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11501,curation_candidate,16796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11502,curation_candidate,18014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11503,curation_candidate,18345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11504,curation_candidate,18463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11505,curation_candidate,18565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11506,curation_candidate,18988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11507,curation_candidate,20282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11508,curation_candidate,20333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11509,curation_candidate,20944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11510,curation_candidate,20996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11511,curation_candidate,21684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11512,curation_candidate,22147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11513,curation_candidate,22267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11514,curation_candidate,22533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11515,curation_candidate,22883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11516,curation_candidate,23055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11517,curation_candidate,23130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11518,curation_candidate,23524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11519,curation_candidate,23765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11520,curation_candidate,24616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11521,curation_candidate,25132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11522,curation_candidate,25261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11523,curation_candidate,27077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11524,curation_candidate,27109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11525,curation_candidate,27179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11526,curation_candidate,27227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11527,curation_candidate,27953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11528,curation_candidate,28426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11529,curation_candidate,28828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
11530,curation_candidate,28926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11531,curation_candidate,29203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11532,curation_candidate,29286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11533,curation_candidate,29542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11534,curation_candidate,29817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11535,curation_candidate,30292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11536,curation_candidate,30299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11537,curation_candidate,30314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11538,curation_candidate,30349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11539,curation_candidate,30408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11540,curation_candidate,30630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11541,curation_candidate,31170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11542,curation_candidate,31806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11543,curation_candidate,32247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11544,curation_candidate,32639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11545,curation_candidate,33522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11546,curation_candidate,35446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11547,curation_candidate,36564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11548,curation_candidate,36771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11549,curation_candidate,37443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11550,curation_candidate,10605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11551,curation_candidate,10610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11552,curation_candidate,10826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11553,curation_candidate,11044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11554,curation_candidate,11046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11555,curation_candidate,11048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11556,curation_candidate,11677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11557,curation_candidate,11679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11558,curation_candidate,11683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11559,curation_candidate,11685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11560,curation_candidate,11688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11561,curation_candidate,11689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11562,curation_candidate,11693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11563,curation_candidate,15118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
11564,curation_candidate,15247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11565,curation_candidate,15249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11566,curation_candidate,15253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
11567,curation_candidate,15257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11568,curation_candidate,16179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11569,curation_candidate,16189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11570,curation_candidate,16190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11571,curation_candidate,16194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11572,curation_candidate,16201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11573,curation_candidate,16208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11574,curation_candidate,16209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11575,curation_candidate,16212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11576,curation_candidate,16217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11577,curation_candidate,16219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11578,curation_candidate,16222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11579,curation_candidate,16226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11580,curation_candidate,17685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11581,curation_candidate,17692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11582,curation_candidate,17772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11583,curation_candidate,18153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11584,curation_candidate,18333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11585,curation_candidate,18985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11586,curation_candidate,19001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11587,curation_candidate,20192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11588,curation_candidate,20872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11589,curation_candidate,20873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11590,curation_candidate,21410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11591,curation_candidate,21810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11592,curation_candidate,22046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11593,curation_candidate,22278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11594,curation_candidate,22501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11595,curation_candidate,22504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11596,curation_candidate,22803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11597,curation_candidate,22804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11598,curation_candidate,23172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11599,curation_candidate,23625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11600,curation_candidate,23732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11601,curation_candidate,24333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11602,curation_candidate,24774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11603,curation_candidate,27616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11604,curation_candidate,27924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11605,curation_candidate,28435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11606,curation_candidate,29284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11607,curation_candidate,29538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11608,curation_candidate,29789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
11609,curation_candidate,29872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11610,curation_candidate,29936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11611,curation_candidate,30481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11612,curation_candidate,30778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11613,curation_candidate,31155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11614,curation_candidate,31292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11615,curation_candidate,31692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11616,curation_candidate,31792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11617,curation_candidate,31986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11618,curation_candidate,32711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11619,curation_candidate,32907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11620,curation_candidate,32955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11621,curation_candidate,33100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11622,curation_candidate,34938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11623,curation_candidate,35375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11624,curation_candidate,35587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11625,curation_candidate,36830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11626,curation_candidate,36863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11627,curation_candidate,36903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11628,curation_candidate,37071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11629,curation_candidate,37149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11630,curation_candidate,37231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11631,curation_candidate,37510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11632,curation_candidate,10863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11633,curation_candidate,10907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11634,curation_candidate,15259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11635,curation_candidate,15266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11636,curation_candidate,16232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11637,curation_candidate,16233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11638,curation_candidate,16237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11639,curation_candidate,16238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11640,curation_candidate,16242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11641,curation_candidate,16463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11642,curation_candidate,16541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11643,curation_candidate,16563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11644,curation_candidate,16944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11645,curation_candidate,17185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11646,curation_candidate,17402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11647,curation_candidate,17427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11648,curation_candidate,17599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11649,curation_candidate,17604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11650,curation_candidate,18034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11651,curation_candidate,18244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11652,curation_candidate,18265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11653,curation_candidate,18567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11654,curation_candidate,18595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11655,curation_candidate,18781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11656,curation_candidate,18950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11657,curation_candidate,19737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11658,curation_candidate,19841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11659,curation_candidate,19904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11660,curation_candidate,20240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11661,curation_candidate,20305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11662,curation_candidate,20387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11663,curation_candidate,21034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11664,curation_candidate,21051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11665,curation_candidate,21526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11666,curation_candidate,21595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11667,curation_candidate,21597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11668,curation_candidate,21728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11669,curation_candidate,21807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11670,curation_candidate,21817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11671,curation_candidate,22162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11672,curation_candidate,22460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11673,curation_candidate,22668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11674,curation_candidate,23300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11675,curation_candidate,23329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11676,curation_candidate,23356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11677,curation_candidate,23425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11678,curation_candidate,23512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11679,curation_candidate,24143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11680,curation_candidate,24219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11681,curation_candidate,24298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11682,curation_candidate,24350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11683,curation_candidate,24512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11684,curation_candidate,24788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11685,curation_candidate,24800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11686,curation_candidate,24850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11687,curation_candidate,24886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11688,curation_candidate,25418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11689,curation_candidate,25478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11690,curation_candidate,26083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11691,curation_candidate,26478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11692,curation_candidate,26735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11693,curation_candidate,26994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11694,curation_candidate,27228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11695,curation_candidate,28717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11696,curation_candidate,28783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
11697,curation_candidate,29149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11698,curation_candidate,29274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11699,curation_candidate,29539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11700,curation_candidate,29788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11701,curation_candidate,29805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11702,curation_candidate,29818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11703,curation_candidate,29822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11704,curation_candidate,29890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11705,curation_candidate,30356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11706,curation_candidate,30651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11707,curation_candidate,30682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11708,curation_candidate,30762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11709,curation_candidate,30781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11710,curation_candidate,30864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11711,curation_candidate,30984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11712,curation_candidate,31108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11713,curation_candidate,31189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11714,curation_candidate,31289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11715,curation_candidate,31647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11716,curation_candidate,32268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11717,curation_candidate,32855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11718,curation_candidate,33318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11719,curation_candidate,33678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11720,curation_candidate,34316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11721,curation_candidate,34592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11722,curation_candidate,35727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11723,curation_candidate,36459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11724,curation_candidate,36548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11725,curation_candidate,36699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11726,curation_candidate,37038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11727,curation_candidate,37153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11728,curation_candidate,10857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11729,curation_candidate,11709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11730,curation_candidate,11711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11731,curation_candidate,15091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11732,curation_candidate,15122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11733,curation_candidate,15277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11734,curation_candidate,15278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11735,curation_candidate,15280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11736,curation_candidate,16262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11737,curation_candidate,16265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11738,curation_candidate,16350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11739,curation_candidate,16679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11740,curation_candidate,16776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11741,curation_candidate,17131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11742,curation_candidate,17231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11743,curation_candidate,18051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11744,curation_candidate,18137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11745,curation_candidate,18384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11746,curation_candidate,18522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11747,curation_candidate,19178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11748,curation_candidate,19200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11749,curation_candidate,19480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11750,curation_candidate,19642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11751,curation_candidate,19982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11752,curation_candidate,20040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11753,curation_candidate,20115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11754,curation_candidate,20150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11755,curation_candidate,20307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11756,curation_candidate,20472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11757,curation_candidate,21146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11758,curation_candidate,21195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11759,curation_candidate,21250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11760,curation_candidate,21315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11761,curation_candidate,21354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11762,curation_candidate,21608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11763,curation_candidate,22503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11764,curation_candidate,22549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11765,curation_candidate,22554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11766,curation_candidate,22613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11767,curation_candidate,23137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11768,curation_candidate,23268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11769,curation_candidate,23468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11770,curation_candidate,23499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11771,curation_candidate,23554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11772,curation_candidate,23589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11773,curation_candidate,23725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11774,curation_candidate,24000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11775,curation_candidate,24232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11776,curation_candidate,24313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11777,curation_candidate,24485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11778,curation_candidate,24633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11779,curation_candidate,24703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11780,curation_candidate,25082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11781,curation_candidate,25171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11782,curation_candidate,25210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11783,curation_candidate,25288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11784,curation_candidate,25609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11785,curation_candidate,25662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11786,curation_candidate,26185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11787,curation_candidate,26481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11788,curation_candidate,26538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11789,curation_candidate,26586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11790,curation_candidate,26637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11791,curation_candidate,26727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11792,curation_candidate,26899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11793,curation_candidate,27151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11794,curation_candidate,27847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11795,curation_candidate,29186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11796,curation_candidate,29249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11797,curation_candidate,29917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11798,curation_candidate,30564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
11799,curation_candidate,30572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11800,curation_candidate,30856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11801,curation_candidate,30972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11802,curation_candidate,31279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11803,curation_candidate,31424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11804,curation_candidate,32203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11805,curation_candidate,32652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11806,curation_candidate,32669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11807,curation_candidate,32767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11808,curation_candidate,33230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11809,curation_candidate,34628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11810,curation_candidate,35157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11811,curation_candidate,35554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11812,curation_candidate,35575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11813,curation_candidate,36253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11814,curation_candidate,36280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11815,curation_candidate,36677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11816,curation_candidate,36727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11817,curation_candidate,36761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11818,curation_candidate,37140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11819,curation_candidate,37333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11820,curation_candidate,37491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11821,curation_candidate,38117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11822,curation_candidate,10858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11823,curation_candidate,15282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11824,curation_candidate,15287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11825,curation_candidate,16286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11826,curation_candidate,16287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11827,curation_candidate,16290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11828,curation_candidate,16293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11829,curation_candidate,16294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11830,curation_candidate,16298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11831,curation_candidate,16456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11832,curation_candidate,17063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11833,curation_candidate,17113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11834,curation_candidate,17118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
11835,curation_candidate,17221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11836,curation_candidate,17313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11837,curation_candidate,17502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11838,curation_candidate,17850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11839,curation_candidate,17854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11840,curation_candidate,18151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11841,curation_candidate,18271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11842,curation_candidate,18535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11843,curation_candidate,18676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11844,curation_candidate,19164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11845,curation_candidate,19287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11846,curation_candidate,19422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11847,curation_candidate,19686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11848,curation_candidate,20357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11849,curation_candidate,20586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11850,curation_candidate,20856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11851,curation_candidate,21141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11852,curation_candidate,21634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11853,curation_candidate,21693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11854,curation_candidate,21818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11855,curation_candidate,21967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11856,curation_candidate,22023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11857,curation_candidate,22362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11858,curation_candidate,22572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11859,curation_candidate,22605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11860,curation_candidate,22799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11861,curation_candidate,23076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11862,curation_candidate,23179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11863,curation_candidate,23531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11864,curation_candidate,23810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11865,curation_candidate,23896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11866,curation_candidate,24180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11867,curation_candidate,24203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11868,curation_candidate,24361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11869,curation_candidate,24404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11870,curation_candidate,24636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11871,curation_candidate,24927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11872,curation_candidate,25248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11873,curation_candidate,25324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11874,curation_candidate,25348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11875,curation_candidate,25952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11876,curation_candidate,26579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11877,curation_candidate,26728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11878,curation_candidate,27005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11879,curation_candidate,27463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11880,curation_candidate,27563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11881,curation_candidate,28587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11882,curation_candidate,28982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11883,curation_candidate,30033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11884,curation_candidate,30404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11885,curation_candidate,30634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11886,curation_candidate,31025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11887,curation_candidate,31185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11888,curation_candidate,31579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11889,curation_candidate,31738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11890,curation_candidate,31831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11891,curation_candidate,32046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11892,curation_candidate,32637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11893,curation_candidate,32786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11894,curation_candidate,33174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11895,curation_candidate,33353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11896,curation_candidate,33401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11897,curation_candidate,33425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11898,curation_candidate,33697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11899,curation_candidate,33721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11900,curation_candidate,33982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11901,curation_candidate,34024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11902,curation_candidate,34618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11903,curation_candidate,34646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11904,curation_candidate,36671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11905,curation_candidate,36681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11906,curation_candidate,36700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11907,curation_candidate,36876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11908,curation_candidate,36941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11909,curation_candidate,37122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11910,curation_candidate,37205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11911,curation_candidate,37639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11912,curation_candidate,37973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11913,curation_candidate,10913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11914,curation_candidate,11723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11915,curation_candidate,11726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11916,curation_candidate,15126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11917,curation_candidate,15293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11918,curation_candidate,15294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11919,curation_candidate,15300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11920,curation_candidate,16311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11921,curation_candidate,16315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11922,curation_candidate,16318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
11923,curation_candidate,16583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11924,curation_candidate,16605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11925,curation_candidate,16633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11926,curation_candidate,17028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11927,curation_candidate,17314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11928,curation_candidate,17338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11929,curation_candidate,17557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11930,curation_candidate,17748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11931,curation_candidate,17856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11932,curation_candidate,17935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11933,curation_candidate,17950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11934,curation_candidate,18892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11935,curation_candidate,19009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11936,curation_candidate,19085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11937,curation_candidate,19944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11938,curation_candidate,19990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11939,curation_candidate,20148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11940,curation_candidate,20406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11941,curation_candidate,20456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11942,curation_candidate,20607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11943,curation_candidate,20649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
11944,curation_candidate,21371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11945,curation_candidate,21515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11946,curation_candidate,21593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11947,curation_candidate,21719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11948,curation_candidate,21959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11949,curation_candidate,22002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11950,curation_candidate,22165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
11951,curation_candidate,22215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11952,curation_candidate,22251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11953,curation_candidate,22296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11954,curation_candidate,22515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11955,curation_candidate,22665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11956,curation_candidate,22795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11957,curation_candidate,22829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11958,curation_candidate,23185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11959,curation_candidate,23202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11960,curation_candidate,23257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11961,curation_candidate,23310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11962,curation_candidate,23337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11963,curation_candidate,23390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11964,curation_candidate,23396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11965,curation_candidate,23645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11966,curation_candidate,23761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11967,curation_candidate,23796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11968,curation_candidate,23899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11969,curation_candidate,24335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11970,curation_candidate,24336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11971,curation_candidate,24348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11972,curation_candidate,24432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11973,curation_candidate,24543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11974,curation_candidate,24791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11975,curation_candidate,24868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11976,curation_candidate,24931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11977,curation_candidate,25235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11978,curation_candidate,25253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11979,curation_candidate,25361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11980,curation_candidate,25486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11981,curation_candidate,25505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11982,curation_candidate,25865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
11983,curation_candidate,25993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11984,curation_candidate,26386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11985,curation_candidate,26504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11986,curation_candidate,27067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11987,curation_candidate,27137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11988,curation_candidate,27239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11989,curation_candidate,27242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11990,curation_candidate,27568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11991,curation_candidate,27982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11992,curation_candidate,28202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11993,curation_candidate,28749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
11994,curation_candidate,28753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
11995,curation_candidate,28823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11996,curation_candidate,29037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11997,curation_candidate,29775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
11998,curation_candidate,29894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
11999,curation_candidate,29907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12000,curation_candidate,30320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
12001,curation_candidate,30357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12002,curation_candidate,30396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12003,curation_candidate,30486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12004,curation_candidate,30618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12005,curation_candidate,30633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12006,curation_candidate,30656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12007,curation_candidate,30903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12008,curation_candidate,31036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12009,curation_candidate,31359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12010,curation_candidate,31810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12011,curation_candidate,31977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12012,curation_candidate,32449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12013,curation_candidate,33424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12014,curation_candidate,33651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12015,curation_candidate,33724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12016,curation_candidate,34022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12017,curation_candidate,34056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12018,curation_candidate,34063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12019,curation_candidate,34377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12020,curation_candidate,34464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12021,curation_candidate,34499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12022,curation_candidate,34635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12023,curation_candidate,34743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12024,curation_candidate,34755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12025,curation_candidate,35162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12026,curation_candidate,35540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12027,curation_candidate,35650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12028,curation_candidate,35946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12029,curation_candidate,36332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12030,curation_candidate,36394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12031,curation_candidate,36472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12032,curation_candidate,36501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12033,curation_candidate,36706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12034,curation_candidate,36839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12035,curation_candidate,37134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12036,curation_candidate,37213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12037,curation_candidate,37453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12038,curation_candidate,37505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12039,curation_candidate,37808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12040,curation_candidate,38098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12041,curation_candidate,10885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12042,curation_candidate,11071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12043,curation_candidate,11134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12044,curation_candidate,16532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12045,curation_candidate,16691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12046,curation_candidate,16878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12047,curation_candidate,17056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12048,curation_candidate,17492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12049,curation_candidate,17552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12050,curation_candidate,17753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12051,curation_candidate,18503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12052,curation_candidate,18570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12053,curation_candidate,18590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12054,curation_candidate,19049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12055,curation_candidate,19460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12056,curation_candidate,19527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12057,curation_candidate,19931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12058,curation_candidate,20263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12059,curation_candidate,20289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12060,curation_candidate,20295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12061,curation_candidate,20479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12062,curation_candidate,20535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12063,curation_candidate,20572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12064,curation_candidate,21116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12065,curation_candidate,21140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12066,curation_candidate,21203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12067,curation_candidate,21285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12068,curation_candidate,21972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12069,curation_candidate,22294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12070,curation_candidate,22353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12071,curation_candidate,22454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12072,curation_candidate,22486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12073,curation_candidate,22498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12074,curation_candidate,22500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12075,curation_candidate,22623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12076,curation_candidate,22864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12077,curation_candidate,23119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12078,curation_candidate,23177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12079,curation_candidate,23252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12080,curation_candidate,23480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12081,curation_candidate,23595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12082,curation_candidate,23750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12083,curation_candidate,23995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12084,curation_candidate,23996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12085,curation_candidate,24234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12086,curation_candidate,24390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12087,curation_candidate,24656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12088,curation_candidate,25057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12089,curation_candidate,25081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12090,curation_candidate,25245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12091,curation_candidate,25275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12092,curation_candidate,25282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12093,curation_candidate,25283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12094,curation_candidate,25551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12095,curation_candidate,25610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12096,curation_candidate,25790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12097,curation_candidate,25815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12098,curation_candidate,26589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12099,curation_candidate,26842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12100,curation_candidate,26851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12101,curation_candidate,26888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12102,curation_candidate,27047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
12103,curation_candidate,27739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12104,curation_candidate,27801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12105,curation_candidate,28615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12106,curation_candidate,29285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12107,curation_candidate,29844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12108,curation_candidate,29845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12109,curation_candidate,30076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12110,curation_candidate,30325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12111,curation_candidate,30509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12112,curation_candidate,30547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12113,curation_candidate,30591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12114,curation_candidate,30609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12115,curation_candidate,30645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12116,curation_candidate,30905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12117,curation_candidate,30934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12118,curation_candidate,31345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12119,curation_candidate,31633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12120,curation_candidate,32159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12121,curation_candidate,32740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12122,curation_candidate,32752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12123,curation_candidate,33106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12124,curation_candidate,33479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12125,curation_candidate,33886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12126,curation_candidate,33921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12127,curation_candidate,33950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12128,curation_candidate,34216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12129,curation_candidate,34293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12130,curation_candidate,34448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12131,curation_candidate,34576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12132,curation_candidate,34709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
12133,curation_candidate,35017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12134,curation_candidate,35612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12135,curation_candidate,36046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12136,curation_candidate,36735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12137,curation_candidate,36795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12138,curation_candidate,36841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
12139,curation_candidate,36890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12140,curation_candidate,36997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12141,curation_candidate,36999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12142,curation_candidate,37028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12143,curation_candidate,37489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12144,curation_candidate,37780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12145,curation_candidate,37987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12146,curation_candidate,38123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12147,curation_candidate,38200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12148,curation_candidate,11731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12149,curation_candidate,11739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
12150,curation_candidate,16431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12151,curation_candidate,16760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12152,curation_candidate,16799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12153,curation_candidate,17266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12154,curation_candidate,17422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12155,curation_candidate,17477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12156,curation_candidate,17807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12157,curation_candidate,17816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12158,curation_candidate,17913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12159,curation_candidate,18199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12160,curation_candidate,18365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12161,curation_candidate,18651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12162,curation_candidate,18818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12163,curation_candidate,19167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12164,curation_candidate,19193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12165,curation_candidate,19935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
12166,curation_candidate,20129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12167,curation_candidate,20156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12168,curation_candidate,20185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12169,curation_candidate,20197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12170,curation_candidate,20745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12171,curation_candidate,20859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12172,curation_candidate,21002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12173,curation_candidate,21279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12174,curation_candidate,21376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12175,curation_candidate,21394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12176,curation_candidate,21466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12177,curation_candidate,21559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12178,curation_candidate,21600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12179,curation_candidate,21690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12180,curation_candidate,21708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12181,curation_candidate,22074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12182,curation_candidate,22334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12183,curation_candidate,22670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12184,curation_candidate,23406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12185,curation_candidate,23523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12186,curation_candidate,23592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12187,curation_candidate,23614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12188,curation_candidate,23671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12189,curation_candidate,23785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12190,curation_candidate,23929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12191,curation_candidate,23964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12192,curation_candidate,24078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12193,curation_candidate,24131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12194,curation_candidate,24139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12195,curation_candidate,24321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12196,curation_candidate,24435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12197,curation_candidate,24463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12198,curation_candidate,24627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12199,curation_candidate,24629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12200,curation_candidate,24690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12201,curation_candidate,24756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12202,curation_candidate,24758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12203,curation_candidate,24985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12204,curation_candidate,25270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12205,curation_candidate,25381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12206,curation_candidate,25412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12207,curation_candidate,25461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12208,curation_candidate,25465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12209,curation_candidate,25502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12210,curation_candidate,25743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12211,curation_candidate,25745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12212,curation_candidate,26128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12213,curation_candidate,26413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12214,curation_candidate,26445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12215,curation_candidate,26949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12216,curation_candidate,27097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12217,curation_candidate,27154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12218,curation_candidate,27192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12219,curation_candidate,27264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12220,curation_candidate,27371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12221,curation_candidate,27834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12222,curation_candidate,28457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12223,curation_candidate,29213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12224,curation_candidate,29240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12225,curation_candidate,29428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12226,curation_candidate,29780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12227,curation_candidate,29918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12228,curation_candidate,29973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12229,curation_candidate,29982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
12230,curation_candidate,30078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12231,curation_candidate,30123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12232,curation_candidate,30251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12233,curation_candidate,30295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12234,curation_candidate,30367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12235,curation_candidate,30447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12236,curation_candidate,30614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12237,curation_candidate,30667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12238,curation_candidate,30787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12239,curation_candidate,30821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12240,curation_candidate,30843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12241,curation_candidate,30851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12242,curation_candidate,31050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12243,curation_candidate,31249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12244,curation_candidate,31320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12245,curation_candidate,31339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12246,curation_candidate,31501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12247,curation_candidate,31595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12248,curation_candidate,31676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12249,curation_candidate,31777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12250,curation_candidate,31809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12251,curation_candidate,31811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12252,curation_candidate,31827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12253,curation_candidate,31902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12254,curation_candidate,32084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12255,curation_candidate,32112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12256,curation_candidate,32191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12257,curation_candidate,32368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12258,curation_candidate,32398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12259,curation_candidate,32883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12260,curation_candidate,33037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12261,curation_candidate,33073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12262,curation_candidate,33088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12263,curation_candidate,33481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12264,curation_candidate,33676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
12265,curation_candidate,33776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12266,curation_candidate,33779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12267,curation_candidate,33856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12268,curation_candidate,33858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12269,curation_candidate,33871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12270,curation_candidate,33924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12271,curation_candidate,34277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12272,curation_candidate,34347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12273,curation_candidate,34695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12274,curation_candidate,34768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12275,curation_candidate,34882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12276,curation_candidate,35244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12277,curation_candidate,35632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12278,curation_candidate,35879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
12279,curation_candidate,35888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12280,curation_candidate,35977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12281,curation_candidate,36011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12282,curation_candidate,36513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12283,curation_candidate,36553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12284,curation_candidate,36798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12285,curation_candidate,36849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12286,curation_candidate,36869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12287,curation_candidate,36887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12288,curation_candidate,36899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12289,curation_candidate,36906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12290,curation_candidate,36949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12291,curation_candidate,36993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12292,curation_candidate,37096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12293,curation_candidate,37183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12294,curation_candidate,37217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12295,curation_candidate,37222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12296,curation_candidate,37400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12297,curation_candidate,37413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12298,curation_candidate,37699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12299,curation_candidate,37739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12300,curation_candidate,37886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12301,curation_candidate,37983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12302,curation_candidate,38287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12303,curation_candidate,10887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12304,curation_candidate,10915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12305,curation_candidate,11744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
12306,curation_candidate,11745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12307,curation_candidate,16441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12308,curation_candidate,16472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12309,curation_candidate,16587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12310,curation_candidate,16591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12311,curation_candidate,16674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12312,curation_candidate,16769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12313,curation_candidate,16821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12314,curation_candidate,17012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12315,curation_candidate,17121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12316,curation_candidate,17315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12317,curation_candidate,17329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12318,curation_candidate,17335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12319,curation_candidate,17500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12320,curation_candidate,17708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12321,curation_candidate,17762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12322,curation_candidate,18027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12323,curation_candidate,18115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12324,curation_candidate,18192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12325,curation_candidate,18268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12326,curation_candidate,18276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12327,curation_candidate,18291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12328,curation_candidate,18581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12329,curation_candidate,18663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12330,curation_candidate,18757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12331,curation_candidate,18761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12332,curation_candidate,18780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12333,curation_candidate,18830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12334,curation_candidate,18856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12335,curation_candidate,18989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12336,curation_candidate,19037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12337,curation_candidate,19165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
12338,curation_candidate,19216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12339,curation_candidate,19369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12340,curation_candidate,19535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12341,curation_candidate,19552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12342,curation_candidate,19651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12343,curation_candidate,19761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12344,curation_candidate,19859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12345,curation_candidate,20093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12346,curation_candidate,20117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12347,curation_candidate,20171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12348,curation_candidate,20269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12349,curation_candidate,20301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12350,curation_candidate,20549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12351,curation_candidate,20849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12352,curation_candidate,20908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12353,curation_candidate,22073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12354,curation_candidate,22106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12355,curation_candidate,22322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12356,curation_candidate,22499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12357,curation_candidate,22557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12358,curation_candidate,22574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12359,curation_candidate,22577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12360,curation_candidate,22872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12361,curation_candidate,22893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12362,curation_candidate,22902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12363,curation_candidate,22909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12364,curation_candidate,23088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12365,curation_candidate,23437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12366,curation_candidate,23567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12367,curation_candidate,23632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12368,curation_candidate,23667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12369,curation_candidate,23705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12370,curation_candidate,23741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12371,curation_candidate,23806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12372,curation_candidate,23897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12373,curation_candidate,23975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12374,curation_candidate,24059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12375,curation_candidate,24208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12376,curation_candidate,24342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12377,curation_candidate,24450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12378,curation_candidate,24622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12379,curation_candidate,24646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12380,curation_candidate,24767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12381,curation_candidate,24832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12382,curation_candidate,24837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12383,curation_candidate,24903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12384,curation_candidate,25061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12385,curation_candidate,25405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12386,curation_candidate,25426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12387,curation_candidate,25704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12388,curation_candidate,26391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12389,curation_candidate,26426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12390,curation_candidate,26455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12391,curation_candidate,26998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12392,curation_candidate,27187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12393,curation_candidate,27710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12394,curation_candidate,28436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12395,curation_candidate,28822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12396,curation_candidate,29241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12397,curation_candidate,29393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12398,curation_candidate,29848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12399,curation_candidate,30016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12400,curation_candidate,30045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12401,curation_candidate,30139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12402,curation_candidate,30153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12403,curation_candidate,30300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12404,curation_candidate,30346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12405,curation_candidate,30436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12406,curation_candidate,30478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12407,curation_candidate,30537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12408,curation_candidate,30662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12409,curation_candidate,30690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12410,curation_candidate,30718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12411,curation_candidate,30936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12412,curation_candidate,30953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12413,curation_candidate,31253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12414,curation_candidate,31269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12415,curation_candidate,31329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12416,curation_candidate,31353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12417,curation_candidate,31376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12418,curation_candidate,31554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12419,curation_candidate,31577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12420,curation_candidate,31945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12421,curation_candidate,31998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12422,curation_candidate,32387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12423,curation_candidate,32524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12424,curation_candidate,32862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
12425,curation_candidate,33069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12426,curation_candidate,33180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12427,curation_candidate,33845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12428,curation_candidate,33954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12429,curation_candidate,34167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12430,curation_candidate,34278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12431,curation_candidate,34420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12432,curation_candidate,34471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12433,curation_candidate,34608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12434,curation_candidate,34700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12435,curation_candidate,34752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12436,curation_candidate,34788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12437,curation_candidate,34813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12438,curation_candidate,35016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12439,curation_candidate,35032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12440,curation_candidate,35441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12441,curation_candidate,35448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12442,curation_candidate,35458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12443,curation_candidate,35702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12444,curation_candidate,35958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12445,curation_candidate,36015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12446,curation_candidate,36062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12447,curation_candidate,36360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12448,curation_candidate,36430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12449,curation_candidate,36502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12450,curation_candidate,36558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12451,curation_candidate,36578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12452,curation_candidate,36711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12453,curation_candidate,36764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12454,curation_candidate,36782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12455,curation_candidate,36855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12456,curation_candidate,36864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12457,curation_candidate,36963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12458,curation_candidate,37135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12459,curation_candidate,37136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12460,curation_candidate,37188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12461,curation_candidate,37193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12462,curation_candidate,37279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12463,curation_candidate,37447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12464,curation_candidate,37605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12465,curation_candidate,37701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12466,curation_candidate,37737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12467,curation_candidate,38180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12468,curation_candidate,38203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12469,curation_candidate,11081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12470,curation_candidate,11083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12471,curation_candidate,16439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12472,curation_candidate,16486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12473,curation_candidate,16493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12474,curation_candidate,16868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
12475,curation_candidate,16875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12476,curation_candidate,17130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12477,curation_candidate,17498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12478,curation_candidate,17561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12479,curation_candidate,17735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12480,curation_candidate,18288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12481,curation_candidate,18304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12482,curation_candidate,18416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12483,curation_candidate,18557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12484,curation_candidate,18707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12485,curation_candidate,18736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12486,curation_candidate,18881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12487,curation_candidate,18898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12488,curation_candidate,18920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12489,curation_candidate,18933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12490,curation_candidate,19234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12491,curation_candidate,19629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12492,curation_candidate,19690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12493,curation_candidate,19785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12494,curation_candidate,19886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12495,curation_candidate,20613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12496,curation_candidate,20851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12497,curation_candidate,20864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12498,curation_candidate,20878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12499,curation_candidate,20913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12500,curation_candidate,21010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12501,curation_candidate,21747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12502,curation_candidate,22145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12503,curation_candidate,22397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12504,curation_candidate,22424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12505,curation_candidate,22586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12506,curation_candidate,22655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12507,curation_candidate,22738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12508,curation_candidate,22743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12509,curation_candidate,22840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12510,curation_candidate,22914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12511,curation_candidate,23053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12512,curation_candidate,23626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12513,curation_candidate,23683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12514,curation_candidate,23685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12515,curation_candidate,23719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12516,curation_candidate,24022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12517,curation_candidate,24050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12518,curation_candidate,24082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12519,curation_candidate,24086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12520,curation_candidate,24098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12521,curation_candidate,24349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12522,curation_candidate,24446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12523,curation_candidate,24563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12524,curation_candidate,24699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12525,curation_candidate,24730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12526,curation_candidate,24740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12527,curation_candidate,24846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12528,curation_candidate,24946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12529,curation_candidate,25205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12530,curation_candidate,25310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12531,curation_candidate,25686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12532,curation_candidate,25735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12533,curation_candidate,25772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12534,curation_candidate,26486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12535,curation_candidate,26738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12536,curation_candidate,26791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12537,curation_candidate,26917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12538,curation_candidate,26947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12539,curation_candidate,27054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12540,curation_candidate,27104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12541,curation_candidate,27789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12542,curation_candidate,28690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
12543,curation_candidate,29581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12544,curation_candidate,29795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12545,curation_candidate,29835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
12546,curation_candidate,29880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12547,curation_candidate,29986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12548,curation_candidate,30008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12549,curation_candidate,30210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12550,curation_candidate,30347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12551,curation_candidate,30470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12552,curation_candidate,30561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12553,curation_candidate,30696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12554,curation_candidate,30770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
12555,curation_candidate,30788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12556,curation_candidate,30884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12557,curation_candidate,30990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12558,curation_candidate,31007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12559,curation_candidate,31432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12560,curation_candidate,31447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12561,curation_candidate,31503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12562,curation_candidate,31699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12563,curation_candidate,31815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12564,curation_candidate,31892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12565,curation_candidate,31949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12566,curation_candidate,32071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12567,curation_candidate,32606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12568,curation_candidate,32802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12569,curation_candidate,32981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12570,curation_candidate,33149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12571,curation_candidate,33343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12572,curation_candidate,33405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12573,curation_candidate,33415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12574,curation_candidate,33669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12575,curation_candidate,33747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12576,curation_candidate,33902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12577,curation_candidate,33946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12578,curation_candidate,34050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12579,curation_candidate,34266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12580,curation_candidate,34631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12581,curation_candidate,34939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12582,curation_candidate,35126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12583,curation_candidate,35468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12584,curation_candidate,35573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12585,curation_candidate,35844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12586,curation_candidate,36025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12587,curation_candidate,36126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12588,curation_candidate,36228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12589,curation_candidate,36443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12590,curation_candidate,36469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12591,curation_candidate,36543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12592,curation_candidate,36628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12593,curation_candidate,36667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12594,curation_candidate,36687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12595,curation_candidate,36745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12596,curation_candidate,36800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12597,curation_candidate,37069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12598,curation_candidate,37087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12599,curation_candidate,37102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12600,curation_candidate,37318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12601,curation_candidate,37331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12602,curation_candidate,37433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12603,curation_candidate,37676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12604,curation_candidate,37945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12605,curation_candidate,38052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12606,curation_candidate,38085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12607,curation_candidate,38100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12608,curation_candidate,11753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12609,curation_candidate,16345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12610,curation_candidate,16379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12611,curation_candidate,16825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12612,curation_candidate,16935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
12613,curation_candidate,16942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12614,curation_candidate,17010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12615,curation_candidate,17111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12616,curation_candidate,17539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12617,curation_candidate,18235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12618,curation_candidate,18349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12619,curation_candidate,18433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12620,curation_candidate,18786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12621,curation_candidate,18850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12622,curation_candidate,18859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12623,curation_candidate,18876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12624,curation_candidate,18952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12625,curation_candidate,18991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12626,curation_candidate,19018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12627,curation_candidate,19191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12628,curation_candidate,19425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
12629,curation_candidate,19650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12630,curation_candidate,20020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12631,curation_candidate,20524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12632,curation_candidate,20721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12633,curation_candidate,20949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12634,curation_candidate,21270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12635,curation_candidate,21278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12636,curation_candidate,21864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12637,curation_candidate,21925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12638,curation_candidate,22781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12639,curation_candidate,23338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12640,curation_candidate,23565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12641,curation_candidate,23649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12642,curation_candidate,23815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12643,curation_candidate,23852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12644,curation_candidate,24076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12645,curation_candidate,24145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12646,curation_candidate,24185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12647,curation_candidate,24506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12648,curation_candidate,24981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12649,curation_candidate,24991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12650,curation_candidate,25001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12651,curation_candidate,25074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12652,curation_candidate,25289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12653,curation_candidate,25397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12654,curation_candidate,25410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12655,curation_candidate,25750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12656,curation_candidate,25768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12657,curation_candidate,25774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12658,curation_candidate,25786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12659,curation_candidate,26182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12660,curation_candidate,26390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12661,curation_candidate,26799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12662,curation_candidate,26866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12663,curation_candidate,27142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12664,curation_candidate,27294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12665,curation_candidate,27325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12666,curation_candidate,27978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12667,curation_candidate,28519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12668,curation_candidate,29010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12669,curation_candidate,29781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12670,curation_candidate,29820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12671,curation_candidate,29868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12672,curation_candidate,29908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12673,curation_candidate,30019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12674,curation_candidate,30479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12675,curation_candidate,30485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
12676,curation_candidate,30518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12677,curation_candidate,30552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12678,curation_candidate,30585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12679,curation_candidate,30658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12680,curation_candidate,30859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12681,curation_candidate,30891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12682,curation_candidate,30915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12683,curation_candidate,31088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12684,curation_candidate,31202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12685,curation_candidate,31228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12686,curation_candidate,31620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12687,curation_candidate,31704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
12688,curation_candidate,31707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12689,curation_candidate,31795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12690,curation_candidate,31914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12691,curation_candidate,31927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12692,curation_candidate,32187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12693,curation_candidate,32465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12694,curation_candidate,32619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12695,curation_candidate,32758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12696,curation_candidate,34177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12697,curation_candidate,34506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12698,curation_candidate,35221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12699,curation_candidate,35255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12700,curation_candidate,35467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12701,curation_candidate,35547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12702,curation_candidate,35570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12703,curation_candidate,35742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12704,curation_candidate,35774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12705,curation_candidate,35833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12706,curation_candidate,36322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12707,curation_candidate,36383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12708,curation_candidate,36399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12709,curation_candidate,36479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12710,curation_candidate,36523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12711,curation_candidate,36665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12712,curation_candidate,36749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12713,curation_candidate,36842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12714,curation_candidate,36861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12715,curation_candidate,37291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12716,curation_candidate,37879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12717,curation_candidate,16383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12718,curation_candidate,16525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12719,curation_candidate,16794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12720,curation_candidate,16955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12721,curation_candidate,17197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12722,curation_candidate,17319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12723,curation_candidate,17356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12724,curation_candidate,17404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12725,curation_candidate,17465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12726,curation_candidate,17720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12727,curation_candidate,17864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12728,curation_candidate,17980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12729,curation_candidate,18480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12730,curation_candidate,18594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12731,curation_candidate,18698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12732,curation_candidate,18849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12733,curation_candidate,18889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12734,curation_candidate,19044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12735,curation_candidate,19120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12736,curation_candidate,19168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12737,curation_candidate,19322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12738,curation_candidate,19472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12739,curation_candidate,19487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12740,curation_candidate,19495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12741,curation_candidate,19542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12742,curation_candidate,19652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12743,curation_candidate,19997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12744,curation_candidate,20026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12745,curation_candidate,20261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12746,curation_candidate,20334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12747,curation_candidate,20380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12748,curation_candidate,20430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
12749,curation_candidate,20453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12750,curation_candidate,20640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12751,curation_candidate,20696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12752,curation_candidate,20734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12753,curation_candidate,20809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12754,curation_candidate,21043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12755,curation_candidate,21181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12756,curation_candidate,21205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12757,curation_candidate,21220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12758,curation_candidate,21301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12759,curation_candidate,21329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12760,curation_candidate,21543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12761,curation_candidate,21858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
12762,curation_candidate,21905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12763,curation_candidate,21926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12764,curation_candidate,22005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12765,curation_candidate,22097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12766,curation_candidate,22462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12767,curation_candidate,22529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12768,curation_candidate,22679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12769,curation_candidate,22681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12770,curation_candidate,22739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12771,curation_candidate,22833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12772,curation_candidate,22911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12773,curation_candidate,22977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12774,curation_candidate,23027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12775,curation_candidate,23033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12776,curation_candidate,23378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12777,curation_candidate,23392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12778,curation_candidate,23556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12779,curation_candidate,23636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12780,curation_candidate,24467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12781,curation_candidate,24697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12782,curation_candidate,24871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12783,curation_candidate,24878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12784,curation_candidate,24939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12785,curation_candidate,24976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12786,curation_candidate,24998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12787,curation_candidate,25033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12788,curation_candidate,25092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12789,curation_candidate,25151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12790,curation_candidate,25178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12791,curation_candidate,25219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12792,curation_candidate,25244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12793,curation_candidate,25583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12794,curation_candidate,25741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12795,curation_candidate,26454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12796,curation_candidate,26590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12797,curation_candidate,26999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12798,curation_candidate,28709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12799,curation_candidate,28800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12800,curation_candidate,29849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12801,curation_candidate,29863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12802,curation_candidate,29895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12803,curation_candidate,29921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12804,curation_candidate,29958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12805,curation_candidate,30085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12806,curation_candidate,30219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12807,curation_candidate,30224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12808,curation_candidate,30257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12809,curation_candidate,30296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12810,curation_candidate,30317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12811,curation_candidate,30321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12812,curation_candidate,30358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12813,curation_candidate,30430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12814,curation_candidate,30437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12815,curation_candidate,30450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12816,curation_candidate,30464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12817,curation_candidate,30484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12818,curation_candidate,30487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12819,curation_candidate,30499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12820,curation_candidate,30548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12821,curation_candidate,30571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12822,curation_candidate,30659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12823,curation_candidate,30676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12824,curation_candidate,30709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12825,curation_candidate,30978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12826,curation_candidate,31024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12827,curation_candidate,31159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12828,curation_candidate,31612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12829,curation_candidate,31693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12830,curation_candidate,31695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12831,curation_candidate,31797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12832,curation_candidate,31881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12833,curation_candidate,31950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12834,curation_candidate,31956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12835,curation_candidate,31968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
12836,curation_candidate,32107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12837,curation_candidate,32132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12838,curation_candidate,32712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12839,curation_candidate,32844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12840,curation_candidate,33146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12841,curation_candidate,33213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12842,curation_candidate,33259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12843,curation_candidate,33674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12844,curation_candidate,33834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12845,curation_candidate,33846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12846,curation_candidate,33882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12847,curation_candidate,33888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12848,curation_candidate,33898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12849,curation_candidate,34230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12850,curation_candidate,34317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12851,curation_candidate,34371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12852,curation_candidate,34702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12853,curation_candidate,34778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12854,curation_candidate,34825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12855,curation_candidate,35546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12856,curation_candidate,35568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12857,curation_candidate,35635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12858,curation_candidate,36162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12859,curation_candidate,36918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12860,curation_candidate,37005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12861,curation_candidate,37194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12862,curation_candidate,37290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12863,curation_candidate,16575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12864,curation_candidate,16655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12865,curation_candidate,16720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12866,curation_candidate,16802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12867,curation_candidate,16981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12868,curation_candidate,17054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12869,curation_candidate,17170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12870,curation_candidate,17181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12871,curation_candidate,17233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12872,curation_candidate,17378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12873,curation_candidate,17620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12874,curation_candidate,17661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12875,curation_candidate,17674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12876,curation_candidate,17861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12877,curation_candidate,17893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12878,curation_candidate,17914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12879,curation_candidate,17918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12880,curation_candidate,18017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12881,curation_candidate,18049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12882,curation_candidate,18116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12883,curation_candidate,18169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12884,curation_candidate,18215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12885,curation_candidate,18295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12886,curation_candidate,18348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12887,curation_candidate,18396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12888,curation_candidate,18526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12889,curation_candidate,18624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12890,curation_candidate,18647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12891,curation_candidate,18683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12892,curation_candidate,18693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12893,curation_candidate,18737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12894,curation_candidate,18814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12895,curation_candidate,18823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12896,curation_candidate,18900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12897,curation_candidate,18999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12898,curation_candidate,19036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12899,curation_candidate,19108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12900,curation_candidate,19206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12901,curation_candidate,19540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12902,curation_candidate,19564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12903,curation_candidate,19879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12904,curation_candidate,20112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12905,curation_candidate,20376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12906,curation_candidate,20471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12907,curation_candidate,20601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12908,curation_candidate,20658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12909,curation_candidate,20803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12910,curation_candidate,20876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12911,curation_candidate,21022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12912,curation_candidate,21039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12913,curation_candidate,21217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12914,curation_candidate,21275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12915,curation_candidate,21544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12916,curation_candidate,21562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12917,curation_candidate,21646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12918,curation_candidate,21739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12919,curation_candidate,21913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12920,curation_candidate,21923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12921,curation_candidate,22467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12922,curation_candidate,22523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12923,curation_candidate,22631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12924,curation_candidate,22969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12925,curation_candidate,23085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12926,curation_candidate,23113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12927,curation_candidate,23191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12928,curation_candidate,23277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12929,curation_candidate,23383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12930,curation_candidate,23680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12931,curation_candidate,23927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12932,curation_candidate,23999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12933,curation_candidate,24156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12934,curation_candidate,24163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12935,curation_candidate,24471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
12936,curation_candidate,24708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12937,curation_candidate,24710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12938,curation_candidate,25131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12939,curation_candidate,25207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12940,curation_candidate,25364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12941,curation_candidate,25529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12942,curation_candidate,25574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12943,curation_candidate,25826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12944,curation_candidate,25915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12945,curation_candidate,25944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12946,curation_candidate,26419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12947,curation_candidate,26708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12948,curation_candidate,26883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12949,curation_candidate,27069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12950,curation_candidate,28523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12951,curation_candidate,29891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12952,curation_candidate,29897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
12953,curation_candidate,29904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12954,curation_candidate,29966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
12955,curation_candidate,30029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12956,curation_candidate,30056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12957,curation_candidate,30100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12958,curation_candidate,30182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12959,curation_candidate,30186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12960,curation_candidate,30221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12961,curation_candidate,30514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12962,curation_candidate,30586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12963,curation_candidate,30601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12964,curation_candidate,30619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12965,curation_candidate,30663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12966,curation_candidate,30715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12967,curation_candidate,30737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12968,curation_candidate,30738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12969,curation_candidate,30799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
12970,curation_candidate,30801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12971,curation_candidate,30816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12972,curation_candidate,30857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12973,curation_candidate,30878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12974,curation_candidate,31000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12975,curation_candidate,31151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12976,curation_candidate,31255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12977,curation_candidate,31284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12978,curation_candidate,31295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
12979,curation_candidate,31507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12980,curation_candidate,31557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12981,curation_candidate,31611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12982,curation_candidate,31644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12983,curation_candidate,31770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12984,curation_candidate,31825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12985,curation_candidate,31877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12986,curation_candidate,31999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12987,curation_candidate,32195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
12988,curation_candidate,32209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12989,curation_candidate,32286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12990,curation_candidate,32607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12991,curation_candidate,32969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12992,curation_candidate,33053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12993,curation_candidate,33104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12994,curation_candidate,33410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12995,curation_candidate,33764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12996,curation_candidate,34086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
12997,curation_candidate,34582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12998,curation_candidate,34804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
12999,curation_candidate,35223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13000,curation_candidate,35355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13001,curation_candidate,36223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13002,curation_candidate,36433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13003,curation_candidate,36915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13004,curation_candidate,37357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13005,curation_candidate,37380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13006,curation_candidate,37419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13007,curation_candidate,37981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13008,curation_candidate,16380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13009,curation_candidate,16389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
13010,curation_candidate,16401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13011,curation_candidate,16577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13012,curation_candidate,16647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13013,curation_candidate,16838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13014,curation_candidate,16893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13015,curation_candidate,16904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
13016,curation_candidate,17138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13017,curation_candidate,17236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13018,curation_candidate,17618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13019,curation_candidate,17952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13020,curation_candidate,18254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13021,curation_candidate,18302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13022,curation_candidate,18356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13023,curation_candidate,18363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13024,curation_candidate,18641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
13025,curation_candidate,18741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13026,curation_candidate,18816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13027,curation_candidate,18954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13028,curation_candidate,19005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13029,curation_candidate,19016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
13030,curation_candidate,19024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13031,curation_candidate,19137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13032,curation_candidate,19306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13033,curation_candidate,19568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13034,curation_candidate,19608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13035,curation_candidate,19633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13036,curation_candidate,19723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13037,curation_candidate,19843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13038,curation_candidate,19961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13039,curation_candidate,20003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13040,curation_candidate,20009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13041,curation_candidate,20044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13042,curation_candidate,20104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13043,curation_candidate,20239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13044,curation_candidate,20482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13045,curation_candidate,20564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13046,curation_candidate,20772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13047,curation_candidate,20857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13048,curation_candidate,20879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13049,curation_candidate,20955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13050,curation_candidate,21148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13051,curation_candidate,21214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13052,curation_candidate,21254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13053,curation_candidate,21257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13054,curation_candidate,21291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13055,curation_candidate,21609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13056,curation_candidate,21707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13057,curation_candidate,21865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13058,curation_candidate,21917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13059,curation_candidate,22039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13060,curation_candidate,22270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13061,curation_candidate,22352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13062,curation_candidate,22434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13063,curation_candidate,22708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13064,curation_candidate,22965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13065,curation_candidate,23157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13066,curation_candidate,23514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13067,curation_candidate,23527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13068,curation_candidate,23770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13069,curation_candidate,23819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13070,curation_candidate,23911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
13071,curation_candidate,23919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13072,curation_candidate,23945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13073,curation_candidate,24015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13074,curation_candidate,24029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13075,curation_candidate,24184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13076,curation_candidate,24258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13077,curation_candidate,24284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13078,curation_candidate,24417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13079,curation_candidate,24651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13080,curation_candidate,25316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13081,curation_candidate,25445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13082,curation_candidate,25456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13083,curation_candidate,25476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13084,curation_candidate,25705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13085,curation_candidate,25728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13086,curation_candidate,26072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13087,curation_candidate,26487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13088,curation_candidate,26734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13089,curation_candidate,26779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13090,curation_candidate,27459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13091,curation_candidate,28499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13092,curation_candidate,29088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13093,curation_candidate,29206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13094,curation_candidate,29862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13095,curation_candidate,30038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13096,curation_candidate,30040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13097,curation_candidate,30044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13098,curation_candidate,30067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13099,curation_candidate,30113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13100,curation_candidate,30121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13101,curation_candidate,30197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13102,curation_candidate,30273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13103,curation_candidate,30301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13104,curation_candidate,30304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13105,curation_candidate,30403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
13106,curation_candidate,30463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
13107,curation_candidate,30519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13108,curation_candidate,30541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13109,curation_candidate,30753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13110,curation_candidate,30897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13111,curation_candidate,30909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13112,curation_candidate,31068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13113,curation_candidate,31128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13114,curation_candidate,31168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13115,curation_candidate,31278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13116,curation_candidate,31348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13117,curation_candidate,31351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13118,curation_candidate,31384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13119,curation_candidate,31429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13120,curation_candidate,31531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13121,curation_candidate,31575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13122,curation_candidate,31581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13123,curation_candidate,31639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13124,curation_candidate,31722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13125,curation_candidate,31734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13126,curation_candidate,31744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13127,curation_candidate,31828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13128,curation_candidate,31912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13129,curation_candidate,32232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13130,curation_candidate,32467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13131,curation_candidate,32656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13132,curation_candidate,32709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13133,curation_candidate,33118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13134,curation_candidate,33143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13135,curation_candidate,33144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13136,curation_candidate,33173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13137,curation_candidate,33306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13138,curation_candidate,33475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13139,curation_candidate,33763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13140,curation_candidate,33829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13141,curation_candidate,34357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13142,curation_candidate,34424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13143,curation_candidate,34460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13144,curation_candidate,34620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13145,curation_candidate,35204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13146,curation_candidate,35330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13147,curation_candidate,35599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13148,curation_candidate,35812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13149,curation_candidate,35846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13150,curation_candidate,35866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13151,curation_candidate,36010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13152,curation_candidate,36263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13153,curation_candidate,36804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13154,curation_candidate,36808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13155,curation_candidate,36986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13156,curation_candidate,37006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13157,curation_candidate,38204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13158,curation_candidate,16388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13159,curation_candidate,16511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13160,curation_candidate,16546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13161,curation_candidate,16553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13162,curation_candidate,16592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
13163,curation_candidate,16652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13164,curation_candidate,17009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13165,curation_candidate,17047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13166,curation_candidate,17169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13167,curation_candidate,17420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13168,curation_candidate,17484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13169,curation_candidate,17547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13170,curation_candidate,17590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13171,curation_candidate,17800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13172,curation_candidate,17946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13173,curation_candidate,18065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13174,curation_candidate,18108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13175,curation_candidate,18133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13176,curation_candidate,18208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13177,curation_candidate,18392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13178,curation_candidate,18415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13179,curation_candidate,18670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13180,curation_candidate,18689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13181,curation_candidate,18790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13182,curation_candidate,18795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13183,curation_candidate,18839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13184,curation_candidate,18976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13185,curation_candidate,19122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13186,curation_candidate,19150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13187,curation_candidate,19370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13188,curation_candidate,19488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13189,curation_candidate,19504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13190,curation_candidate,19517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13191,curation_candidate,19662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13192,curation_candidate,19937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13193,curation_candidate,20014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13194,curation_candidate,20454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13195,curation_candidate,20513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13196,curation_candidate,20616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13197,curation_candidate,20784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13198,curation_candidate,20962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13199,curation_candidate,21128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13200,curation_candidate,21309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13201,curation_candidate,21444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13202,curation_candidate,21916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13203,curation_candidate,22102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13204,curation_candidate,22112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13205,curation_candidate,22170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13206,curation_candidate,22272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13207,curation_candidate,22415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13208,curation_candidate,22636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13209,curation_candidate,22748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13210,curation_candidate,22753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13211,curation_candidate,22754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13212,curation_candidate,23074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13213,curation_candidate,23115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13214,curation_candidate,23213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13215,curation_candidate,23367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13216,curation_candidate,23423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13217,curation_candidate,23428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13218,curation_candidate,23711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13219,curation_candidate,23834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13220,curation_candidate,24104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13221,curation_candidate,24144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13222,curation_candidate,24431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13223,curation_candidate,24739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13224,curation_candidate,25076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13225,curation_candidate,25098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13226,curation_candidate,25141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13227,curation_candidate,25284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13228,curation_candidate,25474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13229,curation_candidate,25647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13230,curation_candidate,25664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13231,curation_candidate,25838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
13232,curation_candidate,26376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13233,curation_candidate,26499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13234,curation_candidate,27072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13235,curation_candidate,27122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13236,curation_candidate,27128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13237,curation_candidate,27263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13238,curation_candidate,27447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13239,curation_candidate,28873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13240,curation_candidate,29335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13241,curation_candidate,29779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13242,curation_candidate,29827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13243,curation_candidate,29902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13244,curation_candidate,29909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13245,curation_candidate,29932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13246,curation_candidate,29960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13247,curation_candidate,29976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13248,curation_candidate,30072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13249,curation_candidate,30092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13250,curation_candidate,30094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13251,curation_candidate,30117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13252,curation_candidate,30205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13253,curation_candidate,30383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13254,curation_candidate,30384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13255,curation_candidate,30445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13256,curation_candidate,30501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13257,curation_candidate,30511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13258,curation_candidate,30538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13259,curation_candidate,30723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13260,curation_candidate,30877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13261,curation_candidate,30967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13262,curation_candidate,31004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13263,curation_candidate,31012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13264,curation_candidate,31018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13265,curation_candidate,31162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13266,curation_candidate,31293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13267,curation_candidate,31515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13268,curation_candidate,31569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13269,curation_candidate,31607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13270,curation_candidate,31627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13271,curation_candidate,31645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13272,curation_candidate,31670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13273,curation_candidate,31729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13274,curation_candidate,31753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13275,curation_candidate,31771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
13276,curation_candidate,31840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13277,curation_candidate,31874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13278,curation_candidate,31967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13279,curation_candidate,32009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
13280,curation_candidate,32241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13281,curation_candidate,32405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13282,curation_candidate,32421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13283,curation_candidate,32443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13284,curation_candidate,32537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13285,curation_candidate,32742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
13286,curation_candidate,33148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13287,curation_candidate,33197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13288,curation_candidate,33201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13289,curation_candidate,33244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13290,curation_candidate,33471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13291,curation_candidate,33673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13292,curation_candidate,33933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13293,curation_candidate,34047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13294,curation_candidate,34102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13295,curation_candidate,34143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13296,curation_candidate,34164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13297,curation_candidate,34430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13298,curation_candidate,34461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13299,curation_candidate,34530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13300,curation_candidate,34536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13301,curation_candidate,34595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13302,curation_candidate,34729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
13303,curation_candidate,35134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13304,curation_candidate,35176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13305,curation_candidate,35252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13306,curation_candidate,35285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13307,curation_candidate,35379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13308,curation_candidate,35609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13309,curation_candidate,35695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13310,curation_candidate,36138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13311,curation_candidate,36204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13312,curation_candidate,36240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13313,curation_candidate,36324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13314,curation_candidate,36401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13315,curation_candidate,36634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13316,curation_candidate,36843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13317,curation_candidate,36866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13318,curation_candidate,37141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13319,curation_candidate,37207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13320,curation_candidate,37393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13321,curation_candidate,38122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13322,curation_candidate,16387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
13323,curation_candidate,16478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13324,curation_candidate,16516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13325,curation_candidate,16620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13326,curation_candidate,16707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13327,curation_candidate,16749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13328,curation_candidate,16977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13329,curation_candidate,16995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13330,curation_candidate,17011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13331,curation_candidate,17241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
13332,curation_candidate,17265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13333,curation_candidate,17304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13334,curation_candidate,17734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13335,curation_candidate,17883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13336,curation_candidate,18030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13337,curation_candidate,18121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13338,curation_candidate,18128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13339,curation_candidate,18132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13340,curation_candidate,18281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13341,curation_candidate,18373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13342,curation_candidate,18449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13343,curation_candidate,18451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13344,curation_candidate,18640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13345,curation_candidate,18838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13346,curation_candidate,18840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13347,curation_candidate,19257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13348,curation_candidate,19663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13349,curation_candidate,19705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13350,curation_candidate,19726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13351,curation_candidate,19730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13352,curation_candidate,19866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13353,curation_candidate,19876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13354,curation_candidate,20032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13355,curation_candidate,20078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13356,curation_candidate,20153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13357,curation_candidate,20405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13358,curation_candidate,20474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13359,curation_candidate,20557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13360,curation_candidate,20619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13361,curation_candidate,20647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13362,curation_candidate,20762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13363,curation_candidate,20939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13364,curation_candidate,21016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13365,curation_candidate,21145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13366,curation_candidate,21337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13367,curation_candidate,21514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13368,curation_candidate,21577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13369,curation_candidate,21588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13370,curation_candidate,21620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13371,curation_candidate,21742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13372,curation_candidate,22027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13373,curation_candidate,22059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13374,curation_candidate,22141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13375,curation_candidate,22244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13376,curation_candidate,22303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
13377,curation_candidate,22307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13378,curation_candidate,22455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13379,curation_candidate,22544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13380,curation_candidate,22559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13381,curation_candidate,22749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13382,curation_candidate,23101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13383,curation_candidate,23160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13384,curation_candidate,23190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13385,curation_candidate,23233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13386,curation_candidate,23471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13387,curation_candidate,23787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13388,curation_candidate,23811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13389,curation_candidate,23902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13390,curation_candidate,23961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13391,curation_candidate,24093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13392,curation_candidate,24189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13393,curation_candidate,24310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13394,curation_candidate,24393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13395,curation_candidate,24620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13396,curation_candidate,24634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13397,curation_candidate,24947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13398,curation_candidate,25114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13399,curation_candidate,25293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13400,curation_candidate,25318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13401,curation_candidate,25630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13402,curation_candidate,25711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13403,curation_candidate,25744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13404,curation_candidate,25775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13405,curation_candidate,26466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13406,curation_candidate,27262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13407,curation_candidate,27267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13408,curation_candidate,27813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13409,curation_candidate,27817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13410,curation_candidate,28321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13411,curation_candidate,28781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13412,curation_candidate,28815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13413,curation_candidate,29828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13414,curation_candidate,29919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13415,curation_candidate,29927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13416,curation_candidate,29949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13417,curation_candidate,29963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13418,curation_candidate,30034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13419,curation_candidate,30114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13420,curation_candidate,30238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13421,curation_candidate,30282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13422,curation_candidate,30382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13423,curation_candidate,30557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13424,curation_candidate,30623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13425,curation_candidate,30644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13426,curation_candidate,30733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13427,curation_candidate,30736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13428,curation_candidate,30771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
13429,curation_candidate,30797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13430,curation_candidate,31070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13431,curation_candidate,31193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13432,curation_candidate,31299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13433,curation_candidate,31347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13434,curation_candidate,31481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13435,curation_candidate,31494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13436,curation_candidate,31535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13437,curation_candidate,31541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13438,curation_candidate,31608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13439,curation_candidate,31712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13440,curation_candidate,31730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13441,curation_candidate,31837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13442,curation_candidate,31860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13443,curation_candidate,31873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13444,curation_candidate,32048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13445,curation_candidate,32061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13446,curation_candidate,32303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13447,curation_candidate,32313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13448,curation_candidate,32364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13449,curation_candidate,32460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13450,curation_candidate,32588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13451,curation_candidate,32724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13452,curation_candidate,32882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13453,curation_candidate,33013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13454,curation_candidate,33051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13455,curation_candidate,33089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13456,curation_candidate,33097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13457,curation_candidate,33129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13458,curation_candidate,33290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13459,curation_candidate,33310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13460,curation_candidate,33419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13461,curation_candidate,33519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13462,curation_candidate,33571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13463,curation_candidate,33884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13464,curation_candidate,34014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13465,curation_candidate,34057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
13466,curation_candidate,34194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13467,curation_candidate,34468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13468,curation_candidate,34510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13469,curation_candidate,34513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13470,curation_candidate,34545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13471,curation_candidate,34569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13472,curation_candidate,34650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13473,curation_candidate,34909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13474,curation_candidate,34913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13475,curation_candidate,35067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13476,curation_candidate,35419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13477,curation_candidate,35426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13478,curation_candidate,35756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13479,curation_candidate,35791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13480,curation_candidate,35810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13481,curation_candidate,35815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13482,curation_candidate,35926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13483,curation_candidate,36161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13484,curation_candidate,36212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13485,curation_candidate,36300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13486,curation_candidate,36520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13487,curation_candidate,36857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13488,curation_candidate,36858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13489,curation_candidate,37058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13490,curation_candidate,37064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13491,curation_candidate,37118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13492,curation_candidate,37144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13493,curation_candidate,37358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13494,curation_candidate,37389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13495,curation_candidate,37477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13496,curation_candidate,16412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
13497,curation_candidate,16539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13498,curation_candidate,16629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13499,curation_candidate,16804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13500,curation_candidate,16849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13501,curation_candidate,17246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13502,curation_candidate,17457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13503,curation_candidate,17473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13504,curation_candidate,17626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13505,curation_candidate,17637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13506,curation_candidate,17782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13507,curation_candidate,17808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13508,curation_candidate,17937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13509,curation_candidate,18009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13510,curation_candidate,18045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13511,curation_candidate,18088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13512,curation_candidate,18204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13513,curation_candidate,18242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13514,curation_candidate,18613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13515,curation_candidate,19000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13516,curation_candidate,19146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13517,curation_candidate,19229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13518,curation_candidate,19270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13519,curation_candidate,19466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13520,curation_candidate,19605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13521,curation_candidate,19669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13522,curation_candidate,19872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13523,curation_candidate,20090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13524,curation_candidate,20140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13525,curation_candidate,20354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13526,curation_candidate,20388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13527,curation_candidate,21137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13528,curation_candidate,21164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13529,curation_candidate,21169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13530,curation_candidate,21558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13531,curation_candidate,21592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13532,curation_candidate,21631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13533,curation_candidate,21677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13534,curation_candidate,21698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13535,curation_candidate,21851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13536,curation_candidate,21860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
13537,curation_candidate,22105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13538,curation_candidate,22157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13539,curation_candidate,22756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13540,curation_candidate,22824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13541,curation_candidate,22837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13542,curation_candidate,22855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13543,curation_candidate,22899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13544,curation_candidate,23107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13545,curation_candidate,23167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13546,curation_candidate,23218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13547,curation_candidate,23534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13548,curation_candidate,23972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13549,curation_candidate,24085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13550,curation_candidate,24238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13551,curation_candidate,24294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13552,curation_candidate,24531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13553,curation_candidate,24549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13554,curation_candidate,24798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13555,curation_candidate,24803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13556,curation_candidate,25015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13557,curation_candidate,25037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13558,curation_candidate,25087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13559,curation_candidate,25181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13560,curation_candidate,25716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13561,curation_candidate,25795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13562,curation_candidate,25958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13563,curation_candidate,25990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13564,curation_candidate,26188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13565,curation_candidate,26446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13566,curation_candidate,26550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13567,curation_candidate,27111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13568,curation_candidate,27455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13569,curation_candidate,27986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13570,curation_candidate,29860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13571,curation_candidate,29870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13572,curation_candidate,29915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13573,curation_candidate,29961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13574,curation_candidate,29969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13575,curation_candidate,29979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13576,curation_candidate,29989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13577,curation_candidate,29996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
13578,curation_candidate,30073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13579,curation_candidate,30101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13580,curation_candidate,30122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13581,curation_candidate,30159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13582,curation_candidate,30164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13583,curation_candidate,30265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13584,curation_candidate,30309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13585,curation_candidate,30342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13586,curation_candidate,30352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13587,curation_candidate,30377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13588,curation_candidate,30426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13589,curation_candidate,30443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13590,curation_candidate,30500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13591,curation_candidate,30525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13592,curation_candidate,30595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13593,curation_candidate,30602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13594,curation_candidate,30866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13595,curation_candidate,30904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13596,curation_candidate,30973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13597,curation_candidate,31044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13598,curation_candidate,31065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13599,curation_candidate,31130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13600,curation_candidate,31131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13601,curation_candidate,31149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13602,curation_candidate,31161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13603,curation_candidate,31194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13604,curation_candidate,31211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13605,curation_candidate,31212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13606,curation_candidate,31341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13607,curation_candidate,31370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13608,curation_candidate,31373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13609,curation_candidate,31430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13610,curation_candidate,31439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13611,curation_candidate,31486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13612,curation_candidate,31566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13613,curation_candidate,31604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13614,curation_candidate,31751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13615,curation_candidate,31769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13616,curation_candidate,31801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13617,curation_candidate,31818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13618,curation_candidate,31855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13619,curation_candidate,31876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13620,curation_candidate,31936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13621,curation_candidate,32179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13622,curation_candidate,32308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13623,curation_candidate,32336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13624,curation_candidate,32504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13625,curation_candidate,32605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13626,curation_candidate,32629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13627,curation_candidate,32681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13628,curation_candidate,32764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13629,curation_candidate,32853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13630,curation_candidate,33056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13631,curation_candidate,33354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13632,curation_candidate,33470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13633,curation_candidate,33598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13634,curation_candidate,33654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13635,curation_candidate,33718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13636,curation_candidate,33719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13637,curation_candidate,33901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13638,curation_candidate,33928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13639,curation_candidate,34005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13640,curation_candidate,34023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13641,curation_candidate,34130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13642,curation_candidate,34370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13643,curation_candidate,34548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13644,curation_candidate,34705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13645,curation_candidate,34955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13646,curation_candidate,34974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13647,curation_candidate,34983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13648,curation_candidate,35054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13649,curation_candidate,35230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13650,curation_candidate,35357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13651,curation_candidate,35408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13652,curation_candidate,35900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13653,curation_candidate,35925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13654,curation_candidate,36116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13655,curation_candidate,36241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13656,curation_candidate,36316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13657,curation_candidate,36384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13658,curation_candidate,36392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13659,curation_candidate,36756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13660,curation_candidate,37040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13661,curation_candidate,37053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13662,curation_candidate,37181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13663,curation_candidate,37187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13664,curation_candidate,37235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13665,curation_candidate,37317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13666,curation_candidate,37454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13667,curation_candidate,37603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13668,curation_candidate,37882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13669,curation_candidate,16438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13670,curation_candidate,16494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13671,curation_candidate,16566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13672,curation_candidate,16574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13673,curation_candidate,16772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13674,curation_candidate,16817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13675,curation_candidate,16959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13676,curation_candidate,17301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13677,curation_candidate,17767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13678,curation_candidate,18100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13679,curation_candidate,18298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13680,curation_candidate,18650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13681,curation_candidate,18857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13682,curation_candidate,18914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13683,curation_candidate,18959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13684,curation_candidate,19097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13685,curation_candidate,19119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13686,curation_candidate,19158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13687,curation_candidate,19509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13688,curation_candidate,19514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13689,curation_candidate,19716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13690,curation_candidate,19734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13691,curation_candidate,20042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13692,curation_candidate,20403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13693,curation_candidate,21112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13694,curation_candidate,21359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13695,curation_candidate,21443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13696,curation_candidate,21878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13697,curation_candidate,22032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13698,curation_candidate,22193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13699,curation_candidate,22213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13700,curation_candidate,22802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13701,curation_candidate,22954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13702,curation_candidate,23110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13703,curation_candidate,23386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13704,curation_candidate,23478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13705,curation_candidate,23635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13706,curation_candidate,23857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13707,curation_candidate,23871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13708,curation_candidate,24100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13709,curation_candidate,24560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13710,curation_candidate,24625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13711,curation_candidate,24684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13712,curation_candidate,25281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13713,curation_candidate,25534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13714,curation_candidate,25794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13715,curation_candidate,26051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13716,curation_candidate,26403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13717,curation_candidate,27579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13718,curation_candidate,28714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13719,curation_candidate,29806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13720,curation_candidate,29832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13721,curation_candidate,29964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13722,curation_candidate,29970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13723,curation_candidate,30051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13724,curation_candidate,30055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
13725,curation_candidate,30143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13726,curation_candidate,30237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13727,curation_candidate,30256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13728,curation_candidate,30266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13729,curation_candidate,30326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13730,curation_candidate,30381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13731,curation_candidate,30423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13732,curation_candidate,30457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13733,curation_candidate,30461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13734,curation_candidate,30477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
13735,curation_candidate,30655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13736,curation_candidate,30670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13737,curation_candidate,30674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13738,curation_candidate,30691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13739,curation_candidate,30702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13740,curation_candidate,30745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13741,curation_candidate,30802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
13742,curation_candidate,30840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13743,curation_candidate,30863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13744,curation_candidate,30963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13745,curation_candidate,31021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
13746,curation_candidate,31064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13747,curation_candidate,31226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13748,curation_candidate,31270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13749,curation_candidate,31276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13750,curation_candidate,31323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13751,curation_candidate,31340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13752,curation_candidate,31433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13753,curation_candidate,31592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13754,curation_candidate,31641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13755,curation_candidate,31646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13756,curation_candidate,31752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13757,curation_candidate,31875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13758,curation_candidate,32011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13759,curation_candidate,32027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13760,curation_candidate,32044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13761,curation_candidate,32113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13762,curation_candidate,32136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13763,curation_candidate,32181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13764,curation_candidate,32329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13765,curation_candidate,32383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13766,curation_candidate,32389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13767,curation_candidate,32430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13768,curation_candidate,32555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13769,curation_candidate,32664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13770,curation_candidate,32677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13771,curation_candidate,32715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13772,curation_candidate,32801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13773,curation_candidate,32816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13774,curation_candidate,32846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13775,curation_candidate,32854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13776,curation_candidate,33001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13777,curation_candidate,33002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13778,curation_candidate,33126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13779,curation_candidate,33153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13780,curation_candidate,33250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13781,curation_candidate,33467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13782,curation_candidate,33516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13783,curation_candidate,33551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13784,curation_candidate,33714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13785,curation_candidate,33899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13786,curation_candidate,33974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13787,curation_candidate,34039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13788,curation_candidate,34176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13789,curation_candidate,34214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13790,curation_candidate,34308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13791,curation_candidate,34318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13792,curation_candidate,34360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13793,curation_candidate,34484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13794,curation_candidate,34560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13795,curation_candidate,34613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13796,curation_candidate,34667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13797,curation_candidate,34839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13798,curation_candidate,35152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13799,curation_candidate,35233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13800,curation_candidate,35263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13801,curation_candidate,35412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13802,curation_candidate,35479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13803,curation_candidate,35525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13804,curation_candidate,35634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13805,curation_candidate,35723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13806,curation_candidate,35743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13807,curation_candidate,35887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13808,curation_candidate,36022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13809,curation_candidate,36419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13810,curation_candidate,36476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13811,curation_candidate,36614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13812,curation_candidate,36664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13813,curation_candidate,36968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13814,curation_candidate,36985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13815,curation_candidate,37105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13816,curation_candidate,37124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13817,curation_candidate,37125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13818,curation_candidate,37201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13819,curation_candidate,37216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13820,curation_candidate,37255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13821,curation_candidate,37459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13822,curation_candidate,37968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13823,curation_candidate,38140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13824,curation_candidate,16344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13825,curation_candidate,16428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13826,curation_candidate,16445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13827,curation_candidate,17425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13828,curation_candidate,17460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13829,curation_candidate,17601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13830,curation_candidate,17721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13831,curation_candidate,17736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13832,curation_candidate,18229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13833,curation_candidate,18458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13834,curation_candidate,18720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13835,curation_candidate,18974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
13836,curation_candidate,19497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13837,curation_candidate,19845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13838,curation_candidate,20035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13839,curation_candidate,20071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13840,curation_candidate,20719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13841,curation_candidate,21084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13842,curation_candidate,21914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
13843,curation_candidate,22517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13844,curation_candidate,22521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13845,curation_candidate,22579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13846,curation_candidate,22722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13847,curation_candidate,22771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13848,curation_candidate,22841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13849,curation_candidate,23551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13850,curation_candidate,23998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13851,curation_candidate,24067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13852,curation_candidate,24113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13853,curation_candidate,24451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13854,curation_candidate,25701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13855,curation_candidate,27044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13856,curation_candidate,29851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13857,curation_candidate,29854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13858,curation_candidate,29913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13859,curation_candidate,29944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13860,curation_candidate,29945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13861,curation_candidate,29962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13862,curation_candidate,30009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13863,curation_candidate,30098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13864,curation_candidate,30194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13865,curation_candidate,30332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13866,curation_candidate,30354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13867,curation_candidate,30387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13868,curation_candidate,30391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13869,curation_candidate,30400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13870,curation_candidate,30405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13871,curation_candidate,30493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13872,curation_candidate,30520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13873,curation_candidate,30599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13874,curation_candidate,30611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13875,curation_candidate,31014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13876,curation_candidate,31015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13877,curation_candidate,31051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13878,curation_candidate,31056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13879,curation_candidate,31171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13880,curation_candidate,31192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
13881,curation_candidate,31304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13882,curation_candidate,31402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13883,curation_candidate,31453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13884,curation_candidate,31480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13885,curation_candidate,31495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13886,curation_candidate,31666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13887,curation_candidate,31698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13888,curation_candidate,32041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13889,curation_candidate,32069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13890,curation_candidate,32085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13891,curation_candidate,32152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
13892,curation_candidate,32235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13893,curation_candidate,32334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13894,curation_candidate,32425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13895,curation_candidate,32428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13896,curation_candidate,32481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13897,curation_candidate,32579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13898,curation_candidate,32710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13899,curation_candidate,32748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13900,curation_candidate,32766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13901,curation_candidate,32770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13902,curation_candidate,32850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13903,curation_candidate,32879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13904,curation_candidate,32918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13905,curation_candidate,32971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13906,curation_candidate,33033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13907,curation_candidate,33090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13908,curation_candidate,33127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13909,curation_candidate,33128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13910,curation_candidate,33624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13911,curation_candidate,33749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13912,curation_candidate,33787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13913,curation_candidate,33916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13914,curation_candidate,34199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13915,curation_candidate,34220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13916,curation_candidate,34284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13917,curation_candidate,34501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13918,curation_candidate,34570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13919,curation_candidate,34784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13920,curation_candidate,34886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13921,curation_candidate,35358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13922,curation_candidate,35413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13923,curation_candidate,35506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13924,curation_candidate,35620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13925,curation_candidate,35737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13926,curation_candidate,35971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13927,curation_candidate,36077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13928,curation_candidate,36286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13929,curation_candidate,36306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13930,curation_candidate,36335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13931,curation_candidate,36522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13932,curation_candidate,36590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13933,curation_candidate,36644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13934,curation_candidate,36682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13935,curation_candidate,36740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13936,curation_candidate,36881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13937,curation_candidate,36978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13938,curation_candidate,37008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13939,curation_candidate,37067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13940,curation_candidate,37083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13941,curation_candidate,37100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13942,curation_candidate,37196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13943,curation_candidate,37248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13944,curation_candidate,37256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13945,curation_candidate,37479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13946,curation_candidate,37569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13947,curation_candidate,16552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13948,curation_candidate,16874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13949,curation_candidate,17373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13950,curation_candidate,17459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13951,curation_candidate,17586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13952,curation_candidate,17722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13953,curation_candidate,19311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13954,curation_candidate,19673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13955,curation_candidate,19994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13956,curation_candidate,20724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13957,curation_candidate,21054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13958,curation_candidate,21293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13959,curation_candidate,23832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13960,curation_candidate,24892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13961,curation_candidate,25197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13962,curation_candidate,25523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13963,curation_candidate,29790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13964,curation_candidate,29804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13965,curation_candidate,29842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
13966,curation_candidate,30145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13967,curation_candidate,30279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13968,curation_candidate,30523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13969,curation_candidate,30604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13970,curation_candidate,30808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13971,curation_candidate,30986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13972,curation_candidate,31746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13973,curation_candidate,31756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13974,curation_candidate,31888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13975,curation_candidate,31921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13976,curation_candidate,32090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13977,curation_candidate,32199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13978,curation_candidate,32393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13979,curation_candidate,32429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13980,curation_candidate,32439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13981,curation_candidate,32477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13982,curation_candidate,32541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13983,curation_candidate,32725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13984,curation_candidate,32911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13985,curation_candidate,32917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13986,curation_candidate,32919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13987,curation_candidate,33227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13988,curation_candidate,33323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13989,curation_candidate,33435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13990,curation_candidate,33684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13991,curation_candidate,33694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13992,curation_candidate,33709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13993,curation_candidate,33965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13994,curation_candidate,34320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13995,curation_candidate,34324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
13996,curation_candidate,34417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13997,curation_candidate,34581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13998,curation_candidate,34688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
13999,curation_candidate,34811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14000,curation_candidate,34834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14001,curation_candidate,35056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14002,curation_candidate,35111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14003,curation_candidate,35196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14004,curation_candidate,35356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14005,curation_candidate,35562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14006,curation_candidate,35886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14007,curation_candidate,36028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14008,curation_candidate,36040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14009,curation_candidate,36296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14010,curation_candidate,36299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14011,curation_candidate,36437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14012,curation_candidate,36554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14013,curation_candidate,36698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14014,curation_candidate,36932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14015,curation_candidate,36933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14016,curation_candidate,36996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14017,curation_candidate,37024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14018,curation_candidate,37035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14019,curation_candidate,37036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14020,curation_candidate,37294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14021,curation_candidate,37329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14022,curation_candidate,37374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14023,curation_candidate,37677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14024,curation_candidate,18798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14025,curation_candidate,25100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14026,curation_candidate,27275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14027,curation_candidate,29799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14028,curation_candidate,29883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14029,curation_candidate,29887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14030,curation_candidate,29934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14031,curation_candidate,29971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14032,curation_candidate,30330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14033,curation_candidate,30466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14034,curation_candidate,30530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14035,curation_candidate,30642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14036,curation_candidate,30741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14037,curation_candidate,30760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14038,curation_candidate,30814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14039,curation_candidate,30858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14040,curation_candidate,30871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14041,curation_candidate,31104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14042,curation_candidate,31264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14043,curation_candidate,31274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14044,curation_candidate,31357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14045,curation_candidate,31651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14046,curation_candidate,31726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14047,curation_candidate,31900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14048,curation_candidate,32099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14049,curation_candidate,32262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14050,curation_candidate,32322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14051,curation_candidate,32450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14052,curation_candidate,32697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14053,curation_candidate,32822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14054,curation_candidate,32901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14055,curation_candidate,33031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14056,curation_candidate,33038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14057,curation_candidate,33142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14058,curation_candidate,33187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14059,curation_candidate,33198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14060,curation_candidate,33238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14061,curation_candidate,33329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14062,curation_candidate,33490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14063,curation_candidate,33568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14064,curation_candidate,33656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14065,curation_candidate,33772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14066,curation_candidate,34256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14067,curation_candidate,34304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14068,curation_candidate,34627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14069,curation_candidate,34699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14070,curation_candidate,34876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14071,curation_candidate,34923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14072,curation_candidate,34937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14073,curation_candidate,36329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14074,curation_candidate,36714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14075,curation_candidate,36988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14076,curation_candidate,37015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14077,curation_candidate,37075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14078,curation_candidate,37133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14079,curation_candidate,37258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14080,curation_candidate,37292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14081,curation_candidate,37299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14082,curation_candidate,24359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14083,curation_candidate,30144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14084,curation_candidate,30154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14085,curation_candidate,30192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14086,curation_candidate,30199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14087,curation_candidate,30267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14088,curation_candidate,30390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14089,curation_candidate,30402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14090,curation_candidate,30452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14091,curation_candidate,30522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14092,curation_candidate,30664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14093,curation_candidate,30900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14094,curation_candidate,31029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14095,curation_candidate,31053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14096,curation_candidate,31309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14097,curation_candidate,31317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14098,curation_candidate,32744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14099,curation_candidate,32749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14100,curation_candidate,33263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14101,curation_candidate,33266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14102,curation_candidate,33411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14103,curation_candidate,33461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14104,curation_candidate,33774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14105,curation_candidate,33812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14106,curation_candidate,34393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14107,curation_candidate,35293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14108,curation_candidate,35498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14109,curation_candidate,35521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14110,curation_candidate,35711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14111,curation_candidate,35937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14112,curation_candidate,36333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14113,curation_candidate,36613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14114,curation_candidate,36787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14115,curation_candidate,37007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14116,curation_candidate,37127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14117,curation_candidate,37176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14118,curation_candidate,37274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14119,curation_candidate,37324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14120,curation_candidate,37416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14121,curation_candidate,37912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14122,curation_candidate,37975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14123,curation_candidate,29830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14124,curation_candidate,29892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14125,curation_candidate,29906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14126,curation_candidate,30379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14127,curation_candidate,30528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14128,curation_candidate,30751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14129,curation_candidate,30807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14130,curation_candidate,30876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14131,curation_candidate,31139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14132,curation_candidate,31449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14133,curation_candidate,31630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14134,curation_candidate,31648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14135,curation_candidate,31803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14136,curation_candidate,31978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14137,curation_candidate,32332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14138,curation_candidate,32609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14139,curation_candidate,32645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14140,curation_candidate,32723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14141,curation_candidate,32861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14142,curation_candidate,33205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14143,curation_candidate,33355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14144,curation_candidate,33576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14145,curation_candidate,33580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14146,curation_candidate,33626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14147,curation_candidate,34042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14148,curation_candidate,34339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14149,curation_candidate,34475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14150,curation_candidate,34494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14151,curation_candidate,34689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14152,curation_candidate,34837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14153,curation_candidate,35226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14154,curation_candidate,35456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14155,curation_candidate,35539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14156,curation_candidate,35571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14157,curation_candidate,36618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14158,curation_candidate,37117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14159,curation_candidate,37119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14160,curation_candidate,37129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14161,curation_candidate,37180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14162,curation_candidate,37212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14163,curation_candidate,37230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14164,curation_candidate,37325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14165,curation_candidate,37366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14166,curation_candidate,37883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14167,curation_candidate,29876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14168,curation_candidate,29987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14169,curation_candidate,30228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14170,curation_candidate,30307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14171,curation_candidate,30362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14172,curation_candidate,30471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14173,curation_candidate,30488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14174,curation_candidate,30555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14175,curation_candidate,30906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14176,curation_candidate,30943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14177,curation_candidate,31091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
14178,curation_candidate,31257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14179,curation_candidate,31344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14180,curation_candidate,31514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14181,curation_candidate,32037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14182,curation_candidate,32081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14183,curation_candidate,32146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14184,curation_candidate,32264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14185,curation_candidate,32344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14186,curation_candidate,32395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14187,curation_candidate,32762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14188,curation_candidate,33052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14189,curation_candidate,33072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14190,curation_candidate,33305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14191,curation_candidate,33376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14192,curation_candidate,33781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14193,curation_candidate,33911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14194,curation_candidate,34002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14195,curation_candidate,34107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14196,curation_candidate,34112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14197,curation_candidate,34233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14198,curation_candidate,34602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14199,curation_candidate,35183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14200,curation_candidate,35422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14201,curation_candidate,35483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14202,curation_candidate,35505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14203,curation_candidate,35607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14204,curation_candidate,35773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14205,curation_candidate,35809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14206,curation_candidate,35914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
14207,curation_candidate,36143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14208,curation_candidate,36378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14209,curation_candidate,36509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14210,curation_candidate,36544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14211,curation_candidate,36956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14212,curation_candidate,37168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14213,curation_candidate,37178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14214,curation_candidate,37199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14215,curation_candidate,37352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14216,curation_candidate,37611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14217,curation_candidate,21032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14218,curation_candidate,22225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14219,curation_candidate,23784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14220,curation_candidate,29445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14221,curation_candidate,29659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14222,curation_candidate,16948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14223,curation_candidate,17647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14224,curation_candidate,17717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14225,curation_candidate,18957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14226,curation_candidate,18977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14227,curation_candidate,19824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14228,curation_candidate,21012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14229,curation_candidate,21978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14230,curation_candidate,22571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14231,curation_candidate,23082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14232,curation_candidate,23479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14233,curation_candidate,23751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14234,curation_candidate,24851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14235,curation_candidate,25014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14236,curation_candidate,25086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14237,curation_candidate,25365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14238,curation_candidate,25572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14239,curation_candidate,26498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14240,curation_candidate,27602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14241,curation_candidate,28037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14242,curation_candidate,28805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14243,curation_candidate,29129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14244,curation_candidate,29163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14245,curation_candidate,29331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14246,curation_candidate,29433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14247,curation_candidate,29440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14248,curation_candidate,29472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14249,curation_candidate,29503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14250,curation_candidate,29505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14251,curation_candidate,29528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14252,curation_candidate,29537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14253,curation_candidate,29573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14254,curation_candidate,29638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14255,curation_candidate,29641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14256,curation_candidate,29663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14257,curation_candidate,29690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14258,curation_candidate,29728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14259,curation_candidate,29746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14260,curation_candidate,29757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14261,curation_candidate,29869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14262,curation_candidate,34205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14263,curation_candidate,34564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14264,curation_candidate,36718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14265,curation_candidate,16414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14266,curation_candidate,16425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14267,curation_candidate,16608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14268,curation_candidate,16698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14269,curation_candidate,17255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14270,curation_candidate,17424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14271,curation_candidate,17541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14272,curation_candidate,17957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14273,curation_candidate,17985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14274,curation_candidate,18269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14275,curation_candidate,18548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14276,curation_candidate,18751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14277,curation_candidate,19149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14278,curation_candidate,19198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14279,curation_candidate,19291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14280,curation_candidate,19352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14281,curation_candidate,19431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14282,curation_candidate,19733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14283,curation_candidate,20008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14284,curation_candidate,20365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14285,curation_candidate,20672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14286,curation_candidate,21779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14287,curation_candidate,21962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14288,curation_candidate,22194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14289,curation_candidate,22232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14290,curation_candidate,22257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14291,curation_candidate,22680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14292,curation_candidate,22779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14293,curation_candidate,22815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14294,curation_candidate,22849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14295,curation_candidate,23096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14296,curation_candidate,23255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14297,curation_candidate,23469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14298,curation_candidate,23704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14299,curation_candidate,23716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14300,curation_candidate,23882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14301,curation_candidate,24150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14302,curation_candidate,24292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14303,curation_candidate,24562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14304,curation_candidate,24893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14305,curation_candidate,24961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14306,curation_candidate,25009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14307,curation_candidate,25084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14308,curation_candidate,25199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14309,curation_candidate,25300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14310,curation_candidate,25393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14311,curation_candidate,25595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14312,curation_candidate,25793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14313,curation_candidate,25989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14314,curation_candidate,26057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14315,curation_candidate,26157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14316,curation_candidate,26159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14317,curation_candidate,26228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14318,curation_candidate,26395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14319,curation_candidate,26442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14320,curation_candidate,26661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14321,curation_candidate,26725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14322,curation_candidate,27349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14323,curation_candidate,27537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14324,curation_candidate,28009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14325,curation_candidate,28376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14326,curation_candidate,28620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14327,curation_candidate,28728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14328,curation_candidate,28740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14329,curation_candidate,28780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14330,curation_candidate,28879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14331,curation_candidate,28960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14332,curation_candidate,28985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14333,curation_candidate,28993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14334,curation_candidate,28998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14335,curation_candidate,29073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14336,curation_candidate,29113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14337,curation_candidate,29192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14338,curation_candidate,29208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14339,curation_candidate,29212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14340,curation_candidate,29214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14341,curation_candidate,29245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14342,curation_candidate,29290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14343,curation_candidate,29295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14344,curation_candidate,29325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14345,curation_candidate,29359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14346,curation_candidate,29370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14347,curation_candidate,29441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14348,curation_candidate,29477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14349,curation_candidate,29496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14350,curation_candidate,29510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14351,curation_candidate,29543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14352,curation_candidate,29549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14353,curation_candidate,29550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14354,curation_candidate,29558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14355,curation_candidate,29561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14356,curation_candidate,29568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14357,curation_candidate,29569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14358,curation_candidate,29579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14359,curation_candidate,29580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14360,curation_candidate,29598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14361,curation_candidate,29604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14362,curation_candidate,29624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14363,curation_candidate,29639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14364,curation_candidate,29669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14365,curation_candidate,29670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14366,curation_candidate,29686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14367,curation_candidate,29717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14368,curation_candidate,29722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14369,curation_candidate,29725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14370,curation_candidate,29731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14371,curation_candidate,29732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14372,curation_candidate,29733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14373,curation_candidate,29768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14374,curation_candidate,30366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14375,curation_candidate,30480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14376,curation_candidate,30765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14377,curation_candidate,31157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14378,curation_candidate,31455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14379,curation_candidate,31563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14380,curation_candidate,32106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14381,curation_candidate,32324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14382,curation_candidate,32378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14383,curation_candidate,34419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14384,curation_candidate,34482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14385,curation_candidate,35290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14386,curation_candidate,36317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14387,curation_candidate,38294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14388,curation_candidate,16323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14389,curation_candidate,16329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14390,curation_candidate,16433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14391,curation_candidate,16601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14392,curation_candidate,16994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
14393,curation_candidate,17083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14394,curation_candidate,18154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14395,curation_candidate,18286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14396,curation_candidate,18314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14397,curation_candidate,18665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14398,curation_candidate,18691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14399,curation_candidate,19373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14400,curation_candidate,19443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14401,curation_candidate,19588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14402,curation_candidate,19664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14403,curation_candidate,19721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14404,curation_candidate,19796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14405,curation_candidate,19804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14406,curation_candidate,20400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14407,curation_candidate,20420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14408,curation_candidate,20780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14409,curation_candidate,21474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14410,curation_candidate,21752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14411,curation_candidate,22044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14412,curation_candidate,22249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14413,curation_candidate,22339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14414,curation_candidate,22414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14415,curation_candidate,22512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14416,curation_candidate,22538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14417,curation_candidate,22596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14418,curation_candidate,22778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14419,curation_candidate,22811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14420,curation_candidate,22826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14421,curation_candidate,23112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14422,curation_candidate,23445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14423,curation_candidate,23502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14424,curation_candidate,23966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14425,curation_candidate,24051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14426,curation_candidate,24094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14427,curation_candidate,24168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14428,curation_candidate,24171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14429,curation_candidate,24193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14430,curation_candidate,24328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14431,curation_candidate,24401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14432,curation_candidate,24515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14433,curation_candidate,24969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14434,curation_candidate,25142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14435,curation_candidate,25150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14436,curation_candidate,25196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14437,curation_candidate,25315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14438,curation_candidate,25447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14439,curation_candidate,25496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14440,curation_candidate,25591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14441,curation_candidate,25637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14442,curation_candidate,25669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14443,curation_candidate,25723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14444,curation_candidate,25732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14445,curation_candidate,25764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14446,curation_candidate,26005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14447,curation_candidate,26039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14448,curation_candidate,26048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14449,curation_candidate,26058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14450,curation_candidate,26078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14451,curation_candidate,26119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14452,curation_candidate,26123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14453,curation_candidate,26137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14454,curation_candidate,26261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14455,curation_candidate,26316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14456,curation_candidate,26393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14457,curation_candidate,26399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14458,curation_candidate,26718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14459,curation_candidate,26904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14460,curation_candidate,27308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14461,curation_candidate,27315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14462,curation_candidate,27329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14463,curation_candidate,27762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14464,curation_candidate,28045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14465,curation_candidate,28292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14466,curation_candidate,28304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14467,curation_candidate,28323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
14468,curation_candidate,28353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14469,curation_candidate,28356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14470,curation_candidate,28417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14471,curation_candidate,28451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14472,curation_candidate,28464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14473,curation_candidate,28481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14474,curation_candidate,28496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14475,curation_candidate,28528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14476,curation_candidate,28529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14477,curation_candidate,28558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14478,curation_candidate,28593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14479,curation_candidate,28596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14480,curation_candidate,28648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
14481,curation_candidate,28696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14482,curation_candidate,28697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14483,curation_candidate,28720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14484,curation_candidate,28791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14485,curation_candidate,28807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14486,curation_candidate,28821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14487,curation_candidate,28834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14488,curation_candidate,28841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14489,curation_candidate,28847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14490,curation_candidate,28938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14491,curation_candidate,28955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14492,curation_candidate,28972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14493,curation_candidate,29004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14494,curation_candidate,29025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14495,curation_candidate,29039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14496,curation_candidate,29052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14497,curation_candidate,29070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14498,curation_candidate,29074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14499,curation_candidate,29108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14500,curation_candidate,29114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14501,curation_candidate,29119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14502,curation_candidate,29124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14503,curation_candidate,29137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14504,curation_candidate,29165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14505,curation_candidate,29182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14506,curation_candidate,29220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14507,curation_candidate,29248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14508,curation_candidate,29250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14509,curation_candidate,29303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14510,curation_candidate,29332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14511,curation_candidate,29384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14512,curation_candidate,29385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14513,curation_candidate,29387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14514,curation_candidate,29402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14515,curation_candidate,29431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14516,curation_candidate,29467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14517,curation_candidate,29512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14518,curation_candidate,29536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14519,curation_candidate,29566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14520,curation_candidate,29584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14521,curation_candidate,29588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14522,curation_candidate,29610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14523,curation_candidate,29616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14524,curation_candidate,29617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14525,curation_candidate,29647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14526,curation_candidate,29671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14527,curation_candidate,29691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14528,curation_candidate,29736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14529,curation_candidate,29739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14530,curation_candidate,29763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14531,curation_candidate,31218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14532,curation_candidate,31886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14533,curation_candidate,32388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14534,curation_candidate,34946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14535,curation_candidate,35770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14536,curation_candidate,36012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14537,curation_candidate,37139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14538,curation_candidate,16396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14539,curation_candidate,16415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14540,curation_candidate,16468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14541,curation_candidate,16960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14542,curation_candidate,17091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14543,curation_candidate,17193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14544,curation_candidate,17632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14545,curation_candidate,17742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14546,curation_candidate,17756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14547,curation_candidate,17813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14548,curation_candidate,18003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14549,curation_candidate,18053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14550,curation_candidate,18126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14551,curation_candidate,18412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14552,curation_candidate,18517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14553,curation_candidate,18865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14554,curation_candidate,19348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14555,curation_candidate,19353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14556,curation_candidate,19850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14557,curation_candidate,19861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14558,curation_candidate,19880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14559,curation_candidate,20079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14560,curation_candidate,20154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14561,curation_candidate,20207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14562,curation_candidate,20343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14563,curation_candidate,20476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14564,curation_candidate,20514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14565,curation_candidate,20814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14566,curation_candidate,20942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14567,curation_candidate,21003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14568,curation_candidate,21346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14569,curation_candidate,21397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14570,curation_candidate,21605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14571,curation_candidate,21702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14572,curation_candidate,21754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14573,curation_candidate,21830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14574,curation_candidate,21888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14575,curation_candidate,21939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14576,curation_candidate,22016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14577,curation_candidate,22109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14578,curation_candidate,22136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14579,curation_candidate,22139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14580,curation_candidate,22247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14581,curation_candidate,22615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14582,curation_candidate,22644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14583,curation_candidate,22657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14584,curation_candidate,22661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14585,curation_candidate,22721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14586,curation_candidate,22789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14587,curation_candidate,22838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14588,curation_candidate,22898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
14589,curation_candidate,22924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14590,curation_candidate,22989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14591,curation_candidate,23040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14592,curation_candidate,23109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14593,curation_candidate,23209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14594,curation_candidate,23332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14595,curation_candidate,23388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14596,curation_candidate,23411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14597,curation_candidate,23413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14598,curation_candidate,23446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14599,curation_candidate,23628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14600,curation_candidate,23629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14601,curation_candidate,23742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14602,curation_candidate,23845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14603,curation_candidate,23860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14604,curation_candidate,23943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14605,curation_candidate,24079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14606,curation_candidate,24124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14607,curation_candidate,24126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
14608,curation_candidate,24129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14609,curation_candidate,24152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14610,curation_candidate,24339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14611,curation_candidate,24641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14612,curation_candidate,24650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14613,curation_candidate,24729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14614,curation_candidate,24752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14615,curation_candidate,24802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14616,curation_candidate,24889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14617,curation_candidate,24936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14618,curation_candidate,25072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14619,curation_candidate,25166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14620,curation_candidate,25172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14621,curation_candidate,25254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14622,curation_candidate,25306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14623,curation_candidate,25384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14624,curation_candidate,25431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14625,curation_candidate,25437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14626,curation_candidate,25604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14627,curation_candidate,25618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14628,curation_candidate,25639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14629,curation_candidate,25742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14630,curation_candidate,25839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14631,curation_candidate,25909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14632,curation_candidate,25919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14633,curation_candidate,25923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14634,curation_candidate,25951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14635,curation_candidate,25969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14636,curation_candidate,25982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14637,curation_candidate,26007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14638,curation_candidate,26064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14639,curation_candidate,26071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14640,curation_candidate,26073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14641,curation_candidate,26077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14642,curation_candidate,26090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14643,curation_candidate,26091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14644,curation_candidate,26104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14645,curation_candidate,26108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14646,curation_candidate,26122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14647,curation_candidate,26134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14648,curation_candidate,26158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14649,curation_candidate,26218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14650,curation_candidate,26220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14651,curation_candidate,26230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14652,curation_candidate,26294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14653,curation_candidate,26330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14654,curation_candidate,26356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14655,curation_candidate,26374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14656,curation_candidate,26415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14657,curation_candidate,26549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14658,curation_candidate,26558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14659,curation_candidate,26626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14660,curation_candidate,26627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14661,curation_candidate,26671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14662,curation_candidate,26837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14663,curation_candidate,26979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14664,curation_candidate,27038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14665,curation_candidate,27061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14666,curation_candidate,27087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14667,curation_candidate,27134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14668,curation_candidate,27176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14669,curation_candidate,27181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14670,curation_candidate,27197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14671,curation_candidate,27222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14672,curation_candidate,27232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14673,curation_candidate,27270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14674,curation_candidate,27283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14675,curation_candidate,27310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14676,curation_candidate,27319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14677,curation_candidate,27386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14678,curation_candidate,27433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14679,curation_candidate,27457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14680,curation_candidate,27462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14681,curation_candidate,27486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14682,curation_candidate,27518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14683,curation_candidate,27618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14684,curation_candidate,27636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14685,curation_candidate,27781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14686,curation_candidate,27993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14687,curation_candidate,28002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14688,curation_candidate,28169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14689,curation_candidate,28196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14690,curation_candidate,28317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14691,curation_candidate,28319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14692,curation_candidate,28414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14693,curation_candidate,28428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14694,curation_candidate,28447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
14695,curation_candidate,28455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14696,curation_candidate,28474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14697,curation_candidate,28475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14698,curation_candidate,28555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14699,curation_candidate,28575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14700,curation_candidate,28609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14701,curation_candidate,28611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14702,curation_candidate,28617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14703,curation_candidate,28635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14704,curation_candidate,28660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14705,curation_candidate,28664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14706,curation_candidate,28673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14707,curation_candidate,28687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14708,curation_candidate,28722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14709,curation_candidate,28733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14710,curation_candidate,28744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14711,curation_candidate,28759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14712,curation_candidate,28765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14713,curation_candidate,28785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14714,curation_candidate,28790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14715,curation_candidate,28801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14716,curation_candidate,28814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14717,curation_candidate,28816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14718,curation_candidate,28820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14719,curation_candidate,28865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14720,curation_candidate,28890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14721,curation_candidate,28918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14722,curation_candidate,28942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14723,curation_candidate,28948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14724,curation_candidate,28963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14725,curation_candidate,28966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14726,curation_candidate,29028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14727,curation_candidate,29042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14728,curation_candidate,29047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14729,curation_candidate,29058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14730,curation_candidate,29071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14731,curation_candidate,29082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14732,curation_candidate,29089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14733,curation_candidate,29090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14734,curation_candidate,29092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14735,curation_candidate,29097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14736,curation_candidate,29102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14737,curation_candidate,29103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14738,curation_candidate,29109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14739,curation_candidate,29135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14740,curation_candidate,29167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14741,curation_candidate,29191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14742,curation_candidate,29204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14743,curation_candidate,29205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14744,curation_candidate,29224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14745,curation_candidate,29231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14746,curation_candidate,29281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14747,curation_candidate,29294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14748,curation_candidate,29297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14749,curation_candidate,29298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14750,curation_candidate,29321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14751,curation_candidate,29336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14752,curation_candidate,29344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14753,curation_candidate,29348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14754,curation_candidate,29350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14755,curation_candidate,29405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
14756,curation_candidate,29417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14757,curation_candidate,29421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14758,curation_candidate,29429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14759,curation_candidate,29449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14760,curation_candidate,29450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14761,curation_candidate,29452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14762,curation_candidate,29465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14763,curation_candidate,29471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14764,curation_candidate,29494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14765,curation_candidate,29497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14766,curation_candidate,29502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14767,curation_candidate,29513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14768,curation_candidate,29517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14769,curation_candidate,29535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14770,curation_candidate,29547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14771,curation_candidate,29556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14772,curation_candidate,29563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14773,curation_candidate,29589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14774,curation_candidate,29592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14775,curation_candidate,29600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14776,curation_candidate,29606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14777,curation_candidate,29619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14778,curation_candidate,29628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14779,curation_candidate,29631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14780,curation_candidate,29658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14781,curation_candidate,29660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14782,curation_candidate,29667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14783,curation_candidate,29668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14784,curation_candidate,29678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14785,curation_candidate,29680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14786,curation_candidate,29692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14787,curation_candidate,29696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14788,curation_candidate,29703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14789,curation_candidate,29710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14790,curation_candidate,29719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14791,curation_candidate,29726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14792,curation_candidate,29727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14793,curation_candidate,29734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14794,curation_candidate,29759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14795,curation_candidate,30246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14796,curation_candidate,30361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14797,curation_candidate,30393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14798,curation_candidate,30468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14799,curation_candidate,30725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14800,curation_candidate,30784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14801,curation_candidate,31285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14802,curation_candidate,32182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14803,curation_candidate,32297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14804,curation_candidate,32630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14805,curation_candidate,32655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14806,curation_candidate,33370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14807,curation_candidate,33988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14808,curation_candidate,34213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14809,curation_candidate,34480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14810,curation_candidate,35074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14811,curation_candidate,35541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14812,curation_candidate,36580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14813,curation_candidate,36592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14814,curation_candidate,36624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14815,curation_candidate,37261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14816,curation_candidate,37564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14817,curation_candidate,37689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14818,curation_candidate,37979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14819,curation_candidate,16413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14820,curation_candidate,16443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14821,curation_candidate,16450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14822,curation_candidate,16482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14823,curation_candidate,16503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14824,curation_candidate,16613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14825,curation_candidate,16627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14826,curation_candidate,16660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14827,curation_candidate,16880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14828,curation_candidate,16945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14829,curation_candidate,17128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14830,curation_candidate,17158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14831,curation_candidate,17345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14832,curation_candidate,17476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14833,curation_candidate,17489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14834,curation_candidate,17509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14835,curation_candidate,17564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14836,curation_candidate,17592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14837,curation_candidate,17683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14838,curation_candidate,17704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14839,curation_candidate,17743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14840,curation_candidate,17797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14841,curation_candidate,18078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14842,curation_candidate,18300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14843,curation_candidate,18474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14844,curation_candidate,18477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14845,curation_candidate,18631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14846,curation_candidate,18635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14847,curation_candidate,18657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14848,curation_candidate,18763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14849,curation_candidate,18813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14850,curation_candidate,18862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14851,curation_candidate,18884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
14852,curation_candidate,18926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14853,curation_candidate,18987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14854,curation_candidate,19050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14855,curation_candidate,19102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14856,curation_candidate,19269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14857,curation_candidate,19279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14858,curation_candidate,19316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14859,curation_candidate,19332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14860,curation_candidate,19423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14861,curation_candidate,19477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14862,curation_candidate,19501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14863,curation_candidate,19570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14864,curation_candidate,19592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14865,curation_candidate,19674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14866,curation_candidate,19687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14867,curation_candidate,19951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14868,curation_candidate,19967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14869,curation_candidate,20052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14870,curation_candidate,20233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14871,curation_candidate,20256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14872,curation_candidate,20391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14873,curation_candidate,20418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14874,curation_candidate,20492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14875,curation_candidate,20498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14876,curation_candidate,20618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14877,curation_candidate,20656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14878,curation_candidate,20805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14879,curation_candidate,20820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14880,curation_candidate,20870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14881,curation_candidate,20895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14882,curation_candidate,20954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14883,curation_candidate,20966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14884,curation_candidate,21110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14885,curation_candidate,21138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14886,curation_candidate,21168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14887,curation_candidate,21183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14888,curation_candidate,21353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14889,curation_candidate,21372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14890,curation_candidate,21408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14891,curation_candidate,21509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14892,curation_candidate,21576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14893,curation_candidate,21632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14894,curation_candidate,21883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14895,curation_candidate,21907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14896,curation_candidate,22122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14897,curation_candidate,22302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14898,curation_candidate,22345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14899,curation_candidate,22437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14900,curation_candidate,22443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14901,curation_candidate,22524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14902,curation_candidate,22547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14903,curation_candidate,22585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14904,curation_candidate,22865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14905,curation_candidate,22887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14906,curation_candidate,22910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14907,curation_candidate,22966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14908,curation_candidate,23017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14909,curation_candidate,23018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14910,curation_candidate,23072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14911,curation_candidate,23161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14912,curation_candidate,23194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14913,curation_candidate,23298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14914,curation_candidate,23361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14915,curation_candidate,23427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14916,curation_candidate,23586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
14917,curation_candidate,23676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14918,curation_candidate,23690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14919,curation_candidate,23702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14920,curation_candidate,23799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14921,curation_candidate,23973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14922,curation_candidate,24103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14923,curation_candidate,24210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14924,curation_candidate,24251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14925,curation_candidate,24293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14926,curation_candidate,24300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14927,curation_candidate,24396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14928,curation_candidate,24445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14929,curation_candidate,24541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14930,curation_candidate,24575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14931,curation_candidate,24805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14932,curation_candidate,24929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14933,curation_candidate,24960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14934,curation_candidate,25173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14935,curation_candidate,25192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14936,curation_candidate,25264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14937,curation_candidate,25682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14938,curation_candidate,25692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14939,curation_candidate,25825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14940,curation_candidate,25852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14941,curation_candidate,25872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14942,curation_candidate,26013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14943,curation_candidate,26044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14944,curation_candidate,26096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14945,curation_candidate,26102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14946,curation_candidate,26107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14947,curation_candidate,26111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14948,curation_candidate,26141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14949,curation_candidate,26213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14950,curation_candidate,26216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14951,curation_candidate,26229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14952,curation_candidate,26247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14953,curation_candidate,26256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14954,curation_candidate,26259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14955,curation_candidate,26292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14956,curation_candidate,26345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14957,curation_candidate,26365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14958,curation_candidate,26367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14959,curation_candidate,26387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14960,curation_candidate,26404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14961,curation_candidate,26482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14962,curation_candidate,26485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14963,curation_candidate,26518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14964,curation_candidate,26535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14965,curation_candidate,26543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14966,curation_candidate,26576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14967,curation_candidate,26676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14968,curation_candidate,26760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14969,curation_candidate,26770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14970,curation_candidate,26790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14971,curation_candidate,26817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14972,curation_candidate,26835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
14973,curation_candidate,26854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14974,curation_candidate,26859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14975,curation_candidate,26860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14976,curation_candidate,26865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
14977,curation_candidate,26890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
14978,curation_candidate,26992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14979,curation_candidate,27030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14980,curation_candidate,27031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14981,curation_candidate,27070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14982,curation_candidate,27082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14983,curation_candidate,27144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14984,curation_candidate,27182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14985,curation_candidate,27198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14986,curation_candidate,27214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14987,curation_candidate,27278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14988,curation_candidate,27346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14989,curation_candidate,27347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
14990,curation_candidate,27402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14991,curation_candidate,27420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14992,curation_candidate,27421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14993,curation_candidate,27434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14994,curation_candidate,27572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14995,curation_candidate,27587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14996,curation_candidate,27600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14997,curation_candidate,27633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14998,curation_candidate,27637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
14999,curation_candidate,27646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15000,curation_candidate,27652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15001,curation_candidate,27662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15002,curation_candidate,27688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15003,curation_candidate,27705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15004,curation_candidate,27743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15005,curation_candidate,27776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15006,curation_candidate,27778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15007,curation_candidate,27798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15008,curation_candidate,27840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15009,curation_candidate,27851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15010,curation_candidate,27874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15011,curation_candidate,27895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15012,curation_candidate,28111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15013,curation_candidate,28125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15014,curation_candidate,28167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15015,curation_candidate,28182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15016,curation_candidate,28183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15017,curation_candidate,28198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15018,curation_candidate,28220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15019,curation_candidate,28231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15020,curation_candidate,28238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15021,curation_candidate,28266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15022,curation_candidate,28298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15023,curation_candidate,28315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15024,curation_candidate,28320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15025,curation_candidate,28328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15026,curation_candidate,28354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15027,curation_candidate,28390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15028,curation_candidate,28401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15029,curation_candidate,28440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15030,curation_candidate,28503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15031,curation_candidate,28577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15032,curation_candidate,28588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15033,curation_candidate,28623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15034,curation_candidate,28625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15035,curation_candidate,28626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15036,curation_candidate,28641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15037,curation_candidate,28643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15038,curation_candidate,28651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15039,curation_candidate,28656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15040,curation_candidate,28667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15041,curation_candidate,28681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15042,curation_candidate,28683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15043,curation_candidate,28693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15044,curation_candidate,28705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15045,curation_candidate,28725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15046,curation_candidate,28754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15047,curation_candidate,28755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15048,curation_candidate,28770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15049,curation_candidate,28799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15050,curation_candidate,28802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15051,curation_candidate,28812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15052,curation_candidate,28827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15053,curation_candidate,28832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15054,curation_candidate,28835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15055,curation_candidate,28843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15056,curation_candidate,28852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15057,curation_candidate,28875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15058,curation_candidate,28901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15059,curation_candidate,28911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15060,curation_candidate,28916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15061,curation_candidate,28929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15062,curation_candidate,28986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15063,curation_candidate,29000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15064,curation_candidate,29022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15065,curation_candidate,29043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15066,curation_candidate,29093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15067,curation_candidate,29100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15068,curation_candidate,29115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15069,curation_candidate,29130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15070,curation_candidate,29133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15071,curation_candidate,29158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15072,curation_candidate,29172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15073,curation_candidate,29179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15074,curation_candidate,29233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15075,curation_candidate,29237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15076,curation_candidate,29244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15077,curation_candidate,29264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15078,curation_candidate,29291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15079,curation_candidate,29299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15080,curation_candidate,29342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15081,curation_candidate,29354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15082,curation_candidate,29407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15083,curation_candidate,29415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15084,curation_candidate,29426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15085,curation_candidate,29442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15086,curation_candidate,29460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15087,curation_candidate,29463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15088,curation_candidate,29468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15089,curation_candidate,29481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15090,curation_candidate,29489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15091,curation_candidate,29504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15092,curation_candidate,29507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15093,curation_candidate,29554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15094,curation_candidate,29572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15095,curation_candidate,29582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15096,curation_candidate,29583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15097,curation_candidate,29613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15098,curation_candidate,29651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15099,curation_candidate,29657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15100,curation_candidate,29664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15101,curation_candidate,29665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15102,curation_candidate,29684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15103,curation_candidate,29694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15104,curation_candidate,29695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15105,curation_candidate,29706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15106,curation_candidate,29744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15107,curation_candidate,29750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15108,curation_candidate,30429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15109,curation_candidate,30467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15110,curation_candidate,30789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15111,curation_candidate,30874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15112,curation_candidate,31090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15113,curation_candidate,31529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15114,curation_candidate,31556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
15115,curation_candidate,31558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15116,curation_candidate,31759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15117,curation_candidate,32063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15118,curation_candidate,32282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15119,curation_candidate,32573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
15120,curation_candidate,32642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15121,curation_candidate,33677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15122,curation_candidate,33813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15123,curation_candidate,34007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15124,curation_candidate,34197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15125,curation_candidate,34215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15126,curation_candidate,34249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15127,curation_candidate,34250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15128,curation_candidate,34446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15129,curation_candidate,34908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
15130,curation_candidate,35210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15131,curation_candidate,35211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15132,curation_candidate,35431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15133,curation_candidate,35497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15134,curation_candidate,35580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15135,curation_candidate,35848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15136,curation_candidate,35893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15137,curation_candidate,36150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15138,curation_candidate,36440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15139,curation_candidate,36542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15140,curation_candidate,36571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15141,curation_candidate,36599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15142,curation_candidate,36746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15143,curation_candidate,37243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15144,curation_candidate,37246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15145,curation_candidate,37874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15146,curation_candidate,38256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15147,curation_candidate,16399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15148,curation_candidate,16410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
15149,curation_candidate,16429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15150,curation_candidate,16650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15151,curation_candidate,16668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15152,curation_candidate,16686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15153,curation_candidate,16730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15154,curation_candidate,16764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15155,curation_candidate,16812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15156,curation_candidate,16824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15157,curation_candidate,16827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15158,curation_candidate,16835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15159,curation_candidate,16840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15160,curation_candidate,16867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15161,curation_candidate,17094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15162,curation_candidate,17177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15163,curation_candidate,17207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15164,curation_candidate,17217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15165,curation_candidate,17332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15166,curation_candidate,17409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15167,curation_candidate,17411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15168,curation_candidate,17413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15169,curation_candidate,17448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15170,curation_candidate,17616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15171,curation_candidate,17630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15172,curation_candidate,17645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15173,curation_candidate,17664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15174,curation_candidate,17688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15175,curation_candidate,17689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15176,curation_candidate,17819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15177,curation_candidate,17847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15178,curation_candidate,18026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15179,curation_candidate,18093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15180,curation_candidate,18166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15181,curation_candidate,18249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15182,curation_candidate,18263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15183,curation_candidate,18277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15184,curation_candidate,18471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15185,curation_candidate,18485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15186,curation_candidate,18504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15187,curation_candidate,18560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15188,curation_candidate,18662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15189,curation_candidate,18787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15190,curation_candidate,18820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15191,curation_candidate,19115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15192,curation_candidate,19118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15193,curation_candidate,19145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15194,curation_candidate,19255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15195,curation_candidate,19572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15196,curation_candidate,19595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15197,curation_candidate,19657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15198,curation_candidate,19671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15199,curation_candidate,19722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15200,curation_candidate,19759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15201,curation_candidate,19842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15202,curation_candidate,19912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15203,curation_candidate,19960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15204,curation_candidate,20069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15205,curation_candidate,20126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15206,curation_candidate,20155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15207,curation_candidate,20183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15208,curation_candidate,20255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15209,curation_candidate,20283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15210,curation_candidate,20317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15211,curation_candidate,20326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15212,curation_candidate,20351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15213,curation_candidate,20438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15214,curation_candidate,20441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15215,curation_candidate,20534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15216,curation_candidate,20815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15217,curation_candidate,20919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15218,curation_candidate,20967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15219,curation_candidate,20975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15220,curation_candidate,20991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15221,curation_candidate,21075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15222,curation_candidate,21165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15223,curation_candidate,21180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15224,curation_candidate,21187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15225,curation_candidate,21189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15226,curation_candidate,21208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15227,curation_candidate,21218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15228,curation_candidate,21415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15229,curation_candidate,21416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15230,curation_candidate,21448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15231,curation_candidate,21453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15232,curation_candidate,21476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15233,curation_candidate,21499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15234,curation_candidate,21582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15235,curation_candidate,21623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15236,curation_candidate,21757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15237,curation_candidate,21799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15238,curation_candidate,21808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15239,curation_candidate,22130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15240,curation_candidate,22191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15241,curation_candidate,22206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15242,curation_candidate,22315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15243,curation_candidate,22316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15244,curation_candidate,22350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15245,curation_candidate,22398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15246,curation_candidate,22433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15247,curation_candidate,22475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15248,curation_candidate,22526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15249,curation_candidate,22562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15250,curation_candidate,22595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15251,curation_candidate,22642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15252,curation_candidate,22662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15253,curation_candidate,22735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15254,curation_candidate,22888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15255,curation_candidate,22974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15256,curation_candidate,23050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15257,curation_candidate,23146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15258,curation_candidate,23223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15259,curation_candidate,23224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15260,curation_candidate,23258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15261,curation_candidate,23288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15262,curation_candidate,23333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15263,curation_candidate,23424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15264,curation_candidate,23598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15265,curation_candidate,23634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15266,curation_candidate,23672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15267,curation_candidate,23958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15268,curation_candidate,23962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15269,curation_candidate,24149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15270,curation_candidate,24158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15271,curation_candidate,24216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15272,curation_candidate,24597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15273,curation_candidate,24681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15274,curation_candidate,24749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15275,curation_candidate,24918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15276,curation_candidate,25011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15277,curation_candidate,25026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15278,curation_candidate,25216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15279,curation_candidate,25251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15280,curation_candidate,25394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15281,curation_candidate,25498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15282,curation_candidate,25580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15283,curation_candidate,25590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15284,curation_candidate,25599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15285,curation_candidate,25676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15286,curation_candidate,25830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15287,curation_candidate,25841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15288,curation_candidate,25857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15289,curation_candidate,25859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15290,curation_candidate,25895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15291,curation_candidate,25898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15292,curation_candidate,25917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15293,curation_candidate,25932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15294,curation_candidate,25936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15295,curation_candidate,25960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15296,curation_candidate,25966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15297,curation_candidate,26045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15298,curation_candidate,26050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15299,curation_candidate,26095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15300,curation_candidate,26138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15301,curation_candidate,26145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15302,curation_candidate,26169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15303,curation_candidate,26177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15304,curation_candidate,26193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15305,curation_candidate,26201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15306,curation_candidate,26206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15307,curation_candidate,26226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15308,curation_candidate,26234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15309,curation_candidate,26250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15310,curation_candidate,26265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15311,curation_candidate,26326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15312,curation_candidate,26344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15313,curation_candidate,26366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15314,curation_candidate,26375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15315,curation_candidate,26432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15316,curation_candidate,26451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15317,curation_candidate,26496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15318,curation_candidate,26524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15319,curation_candidate,26547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15320,curation_candidate,26559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15321,curation_candidate,26570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15322,curation_candidate,26574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15323,curation_candidate,26623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15324,curation_candidate,26677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15325,curation_candidate,26684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15326,curation_candidate,26690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15327,curation_candidate,26722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15328,curation_candidate,26751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15329,curation_candidate,26762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15330,curation_candidate,26808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15331,curation_candidate,26861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15332,curation_candidate,26889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15333,curation_candidate,26907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15334,curation_candidate,26929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15335,curation_candidate,26948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15336,curation_candidate,26990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15337,curation_candidate,27025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15338,curation_candidate,27074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15339,curation_candidate,27075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15340,curation_candidate,27091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15341,curation_candidate,27132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15342,curation_candidate,27135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15343,curation_candidate,27140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15344,curation_candidate,27215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15345,curation_candidate,27256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15346,curation_candidate,27321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15347,curation_candidate,27340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15348,curation_candidate,27348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15349,curation_candidate,27364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15350,curation_candidate,27390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15351,curation_candidate,27418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15352,curation_candidate,27440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15353,curation_candidate,27444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15354,curation_candidate,27465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15355,curation_candidate,27476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15356,curation_candidate,27503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15357,curation_candidate,27504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15358,curation_candidate,27558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15359,curation_candidate,27561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15360,curation_candidate,27574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15361,curation_candidate,27575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15362,curation_candidate,27612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15363,curation_candidate,27615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15364,curation_candidate,27657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15365,curation_candidate,27717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15366,curation_candidate,27773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15367,curation_candidate,27823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15368,curation_candidate,27897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15369,curation_candidate,28001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15370,curation_candidate,28144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15371,curation_candidate,28149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15372,curation_candidate,28189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15373,curation_candidate,28253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15374,curation_candidate,28260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15375,curation_candidate,28290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15376,curation_candidate,28311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15377,curation_candidate,28346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15378,curation_candidate,28349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15379,curation_candidate,28378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15380,curation_candidate,28386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15381,curation_candidate,28391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15382,curation_candidate,28422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15383,curation_candidate,28489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15384,curation_candidate,28494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15385,curation_candidate,28502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15386,curation_candidate,28561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15387,curation_candidate,28572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15388,curation_candidate,28583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15389,curation_candidate,28586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15390,curation_candidate,28634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15391,curation_candidate,28650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15392,curation_candidate,28654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15393,curation_candidate,28657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15394,curation_candidate,28663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15395,curation_candidate,28689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15396,curation_candidate,28704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15397,curation_candidate,28707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15398,curation_candidate,28719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15399,curation_candidate,28724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15400,curation_candidate,28738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15401,curation_candidate,28796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15402,curation_candidate,28826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15403,curation_candidate,28830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15404,curation_candidate,28848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15405,curation_candidate,28851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15406,curation_candidate,28856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15407,curation_candidate,28898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15408,curation_candidate,28917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15409,curation_candidate,28921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15410,curation_candidate,28945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15411,curation_candidate,28946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15412,curation_candidate,28962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15413,curation_candidate,28981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15414,curation_candidate,28992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15415,curation_candidate,28994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15416,curation_candidate,29016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15417,curation_candidate,29020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15418,curation_candidate,29023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15419,curation_candidate,29054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15420,curation_candidate,29079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15421,curation_candidate,29111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15422,curation_candidate,29145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15423,curation_candidate,29148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15424,curation_candidate,29150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15425,curation_candidate,29170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15426,curation_candidate,29171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15427,curation_candidate,29210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15428,curation_candidate,29217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15429,curation_candidate,29259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15430,curation_candidate,29296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15431,curation_candidate,29304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15432,curation_candidate,29334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15433,curation_candidate,29346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15434,curation_candidate,29355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15435,curation_candidate,29372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15436,curation_candidate,29378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15437,curation_candidate,29397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15438,curation_candidate,29413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15439,curation_candidate,29423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15440,curation_candidate,29434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15441,curation_candidate,29456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15442,curation_candidate,29509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15443,curation_candidate,29570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15444,curation_candidate,29585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15445,curation_candidate,29586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15446,curation_candidate,29599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15447,curation_candidate,29611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15448,curation_candidate,29622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15449,curation_candidate,29633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15450,curation_candidate,29634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15451,curation_candidate,29636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15452,curation_candidate,29652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15453,curation_candidate,29677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15454,curation_candidate,29693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15455,curation_candidate,29698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15456,curation_candidate,29701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15457,curation_candidate,29705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15458,curation_candidate,29707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15459,curation_candidate,29708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15460,curation_candidate,29713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15461,curation_candidate,29720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15462,curation_candidate,29735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15463,curation_candidate,29741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15464,curation_candidate,29752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15465,curation_candidate,29754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15466,curation_candidate,29755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15467,curation_candidate,29864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15468,curation_candidate,29865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15469,curation_candidate,30252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15470,curation_candidate,30278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15471,curation_candidate,30331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15472,curation_candidate,30398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15473,curation_candidate,30427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15474,curation_candidate,30540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15475,curation_candidate,30669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15476,curation_candidate,30689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15477,curation_candidate,31032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15478,curation_candidate,31379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15479,curation_candidate,31765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15480,curation_candidate,31783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15481,curation_candidate,32050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15482,curation_candidate,32102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15483,curation_candidate,32351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15484,curation_candidate,32357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15485,curation_candidate,32658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15486,curation_candidate,33952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15487,curation_candidate,34060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15488,curation_candidate,34109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15489,curation_candidate,34165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15490,curation_candidate,34459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15491,curation_candidate,34686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15492,curation_candidate,34830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15493,curation_candidate,34864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15494,curation_candidate,34866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15495,curation_candidate,34921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15496,curation_candidate,35461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15497,curation_candidate,35581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15498,curation_candidate,35593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15499,curation_candidate,35775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15500,curation_candidate,36373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15501,curation_candidate,36403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15502,curation_candidate,36587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15503,curation_candidate,36595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15504,curation_candidate,36750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15505,curation_candidate,36767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15506,curation_candidate,36893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15507,curation_candidate,37011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15508,curation_candidate,37269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15509,curation_candidate,37781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15510,curation_candidate,38080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15511,curation_candidate,16370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15512,curation_candidate,16375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15513,curation_candidate,16526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15514,curation_candidate,16704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15515,curation_candidate,16743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15516,curation_candidate,16751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15517,curation_candidate,16777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15518,curation_candidate,16846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15519,curation_candidate,16968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15520,curation_candidate,17081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15521,curation_candidate,17129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15522,curation_candidate,17213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15523,curation_candidate,17239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15524,curation_candidate,17388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15525,curation_candidate,17389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15526,curation_candidate,17479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15527,curation_candidate,17707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15528,curation_candidate,17749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15529,curation_candidate,17888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15530,curation_candidate,17900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15531,curation_candidate,18119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15532,curation_candidate,18446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15533,curation_candidate,18453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15534,curation_candidate,18554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15535,curation_candidate,18615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15536,curation_candidate,18623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15537,curation_candidate,18628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15538,curation_candidate,18652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15539,curation_candidate,18731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15540,curation_candidate,18878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15541,curation_candidate,18949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15542,curation_candidate,18962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15543,curation_candidate,19169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15544,curation_candidate,19396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15545,curation_candidate,19405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15546,curation_candidate,19448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15547,curation_candidate,19583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15548,curation_candidate,19587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15549,curation_candidate,19593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15550,curation_candidate,19676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15551,curation_candidate,19735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15552,curation_candidate,19792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15553,curation_candidate,19894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15554,curation_candidate,19923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15555,curation_candidate,20017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15556,curation_candidate,20086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15557,curation_candidate,20118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15558,curation_candidate,20189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15559,curation_candidate,20217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15560,curation_candidate,20243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15561,curation_candidate,20314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15562,curation_candidate,20468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15563,curation_candidate,20490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15564,curation_candidate,20530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15565,curation_candidate,20580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15566,curation_candidate,20666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15567,curation_candidate,20676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15568,curation_candidate,20737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15569,curation_candidate,20799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15570,curation_candidate,20925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15571,curation_candidate,20977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15572,curation_candidate,21067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15573,curation_candidate,21080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15574,curation_candidate,21102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15575,curation_candidate,21334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15576,curation_candidate,21358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15577,curation_candidate,21399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15578,curation_candidate,21402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15579,curation_candidate,21462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15580,curation_candidate,21485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15581,curation_candidate,21530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15582,curation_candidate,21540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15583,curation_candidate,21567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15584,curation_candidate,21627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15585,curation_candidate,21686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15586,curation_candidate,21748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15587,curation_candidate,21837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15588,curation_candidate,21949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15589,curation_candidate,21977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15590,curation_candidate,22018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15591,curation_candidate,22026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
15592,curation_candidate,22101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15593,curation_candidate,22133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15594,curation_candidate,22196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15595,curation_candidate,22224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15596,curation_candidate,22333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15597,curation_candidate,22355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15598,curation_candidate,22457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15599,curation_candidate,22494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15600,curation_candidate,22525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15601,curation_candidate,22640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15602,curation_candidate,22678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15603,curation_candidate,22747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15604,curation_candidate,22851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15605,curation_candidate,22873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15606,curation_candidate,22908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15607,curation_candidate,22921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15608,curation_candidate,22926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15609,curation_candidate,23080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15610,curation_candidate,23211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15611,curation_candidate,23244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15612,curation_candidate,23431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15613,curation_candidate,23550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15614,curation_candidate,23558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15615,curation_candidate,23574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15616,curation_candidate,23692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15617,curation_candidate,23844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15618,curation_candidate,23883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15619,curation_candidate,23937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15620,curation_candidate,24083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15621,curation_candidate,24140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15622,curation_candidate,24155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15623,curation_candidate,24358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15624,curation_candidate,24407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15625,curation_candidate,24529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15626,curation_candidate,24595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15627,curation_candidate,24605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15628,curation_candidate,24830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15629,curation_candidate,24862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15630,curation_candidate,24875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15631,curation_candidate,24888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15632,curation_candidate,25065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15633,curation_candidate,25095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15634,curation_candidate,25194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15635,curation_candidate,25403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15636,curation_candidate,25411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15637,curation_candidate,25535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15638,curation_candidate,25548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15639,curation_candidate,25575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15640,curation_candidate,25665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15641,curation_candidate,25695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15642,curation_candidate,25771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15643,curation_candidate,25833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15644,curation_candidate,25854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15645,curation_candidate,25860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15646,curation_candidate,25866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15647,curation_candidate,25924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15648,curation_candidate,25941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15649,curation_candidate,25947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15650,curation_candidate,26028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15651,curation_candidate,26030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15652,curation_candidate,26062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15653,curation_candidate,26066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15654,curation_candidate,26110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15655,curation_candidate,26114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15656,curation_candidate,26127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15657,curation_candidate,26142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15658,curation_candidate,26168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15659,curation_candidate,26196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15660,curation_candidate,26197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15661,curation_candidate,26237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15662,curation_candidate,26245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15663,curation_candidate,26257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15664,curation_candidate,26276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15665,curation_candidate,26279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15666,curation_candidate,26299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15667,curation_candidate,26302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15668,curation_candidate,26310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15669,curation_candidate,26320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15670,curation_candidate,26329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15671,curation_candidate,26342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15672,curation_candidate,26350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15673,curation_candidate,26355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15674,curation_candidate,26360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
15675,curation_candidate,26363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15676,curation_candidate,26371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15677,curation_candidate,26431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15678,curation_candidate,26441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15679,curation_candidate,26480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15680,curation_candidate,26513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15681,curation_candidate,26533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15682,curation_candidate,26536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15683,curation_candidate,26537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15684,curation_candidate,26562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15685,curation_candidate,26569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15686,curation_candidate,26630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15687,curation_candidate,26648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15688,curation_candidate,26711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15689,curation_candidate,26756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15690,curation_candidate,26758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15691,curation_candidate,26806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15692,curation_candidate,26834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15693,curation_candidate,26862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15694,curation_candidate,26868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15695,curation_candidate,26881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15696,curation_candidate,26900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15697,curation_candidate,26945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15698,curation_candidate,26950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15699,curation_candidate,26982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15700,curation_candidate,26986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15701,curation_candidate,27004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15702,curation_candidate,27112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15703,curation_candidate,27115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15704,curation_candidate,27121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15705,curation_candidate,27153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15706,curation_candidate,27159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15707,curation_candidate,27168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15708,curation_candidate,27207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15709,curation_candidate,27220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15710,curation_candidate,27312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15711,curation_candidate,27317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15712,curation_candidate,27320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15713,curation_candidate,27344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15714,curation_candidate,27408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15715,curation_candidate,27426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15716,curation_candidate,27427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15717,curation_candidate,27454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15718,curation_candidate,27466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15719,curation_candidate,27469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15720,curation_candidate,27481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15721,curation_candidate,27505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15722,curation_candidate,27517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15723,curation_candidate,27535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15724,curation_candidate,27557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15725,curation_candidate,27559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15726,curation_candidate,27567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15727,curation_candidate,27592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15728,curation_candidate,27628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15729,curation_candidate,27649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15730,curation_candidate,27658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15731,curation_candidate,27707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15732,curation_candidate,27752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15733,curation_candidate,27780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15734,curation_candidate,27784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15735,curation_candidate,27797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15736,curation_candidate,27880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15737,curation_candidate,27898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15738,curation_candidate,27905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15739,curation_candidate,27934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15740,curation_candidate,27991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15741,curation_candidate,28004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15742,curation_candidate,28028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15743,curation_candidate,28039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15744,curation_candidate,28052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15745,curation_candidate,28054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15746,curation_candidate,28063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15747,curation_candidate,28158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15748,curation_candidate,28186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15749,curation_candidate,28195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15750,curation_candidate,28201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15751,curation_candidate,28213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15752,curation_candidate,28217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15753,curation_candidate,28230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15754,curation_candidate,28243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15755,curation_candidate,28244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15756,curation_candidate,28245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15757,curation_candidate,28277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15758,curation_candidate,28282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15759,curation_candidate,28284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15760,curation_candidate,28300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15761,curation_candidate,28332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15762,curation_candidate,28351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15763,curation_candidate,28364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15764,curation_candidate,28389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15765,curation_candidate,28398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15766,curation_candidate,28469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15767,curation_candidate,28530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15768,curation_candidate,28614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15769,curation_candidate,28628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15770,curation_candidate,28638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15771,curation_candidate,28692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15772,curation_candidate,28735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15773,curation_candidate,28736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15774,curation_candidate,28741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15775,curation_candidate,28811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
15776,curation_candidate,28818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15777,curation_candidate,28864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15778,curation_candidate,28866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15779,curation_candidate,28870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15780,curation_candidate,28927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15781,curation_candidate,28977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15782,curation_candidate,28991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15783,curation_candidate,29019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15784,curation_candidate,29036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15785,curation_candidate,29048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15786,curation_candidate,29062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15787,curation_candidate,29064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15788,curation_candidate,29072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15789,curation_candidate,29075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15790,curation_candidate,29106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15791,curation_candidate,29107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15792,curation_candidate,29122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15793,curation_candidate,29127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15794,curation_candidate,29151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15795,curation_candidate,29188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15796,curation_candidate,29258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15797,curation_candidate,29280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15798,curation_candidate,29292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15799,curation_candidate,29301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15800,curation_candidate,29318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15801,curation_candidate,29341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15802,curation_candidate,29353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15803,curation_candidate,29358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15804,curation_candidate,29369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15805,curation_candidate,29395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15806,curation_candidate,29422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15807,curation_candidate,29427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15808,curation_candidate,29459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15809,curation_candidate,29464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15810,curation_candidate,29519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15811,curation_candidate,29576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15812,curation_candidate,29591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15813,curation_candidate,29602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15814,curation_candidate,29653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15815,curation_candidate,29687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15816,curation_candidate,29700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15817,curation_candidate,29714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15818,curation_candidate,29753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15819,curation_candidate,29765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15820,curation_candidate,29819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15821,curation_candidate,29857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15822,curation_candidate,29899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15823,curation_candidate,30394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15824,curation_candidate,30453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15825,curation_candidate,30515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15826,curation_candidate,30566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15827,curation_candidate,30940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15828,curation_candidate,31382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15829,curation_candidate,31484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15830,curation_candidate,31573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15831,curation_candidate,31617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15832,curation_candidate,31652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15833,curation_candidate,31719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15834,curation_candidate,31796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15835,curation_candidate,32832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15836,curation_candidate,32860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15837,curation_candidate,32948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15838,curation_candidate,33455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15839,curation_candidate,33672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15840,curation_candidate,33992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15841,curation_candidate,34175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15842,curation_candidate,34207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15843,curation_candidate,34265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15844,curation_candidate,34515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15845,curation_candidate,34593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15846,curation_candidate,34636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15847,curation_candidate,34648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15848,curation_candidate,34896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15849,curation_candidate,35060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15850,curation_candidate,35240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15851,curation_candidate,35347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15852,curation_candidate,35433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15853,curation_candidate,35861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15854,curation_candidate,36532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15855,curation_candidate,36710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15856,curation_candidate,36814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15857,curation_candidate,36921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15858,curation_candidate,36967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15859,curation_candidate,37045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15860,curation_candidate,37355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15861,curation_candidate,37690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15862,curation_candidate,38109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15863,curation_candidate,38299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15864,curation_candidate,16500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15865,curation_candidate,16509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15866,curation_candidate,16518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15867,curation_candidate,16614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15868,curation_candidate,16684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15869,curation_candidate,16696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15870,curation_candidate,16710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15871,curation_candidate,16757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15872,curation_candidate,16839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15873,curation_candidate,16950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15874,curation_candidate,16998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15875,curation_candidate,17020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15876,curation_candidate,17242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15877,curation_candidate,17293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15878,curation_candidate,17429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15879,curation_candidate,17534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15880,curation_candidate,17543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15881,curation_candidate,17581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15882,curation_candidate,17611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
15883,curation_candidate,17614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15884,curation_candidate,17687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15885,curation_candidate,17697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15886,curation_candidate,17774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15887,curation_candidate,17845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15888,curation_candidate,17896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15889,curation_candidate,17912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15890,curation_candidate,17919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15891,curation_candidate,17939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15892,curation_candidate,17963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15893,curation_candidate,17988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15894,curation_candidate,18110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15895,curation_candidate,18114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15896,curation_candidate,18224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15897,curation_candidate,18375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15898,curation_candidate,18378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15899,curation_candidate,18444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15900,curation_candidate,18472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15901,curation_candidate,18690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15902,curation_candidate,18793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15903,curation_candidate,18911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15904,curation_candidate,18948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15905,curation_candidate,19129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15906,curation_candidate,19197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15907,curation_candidate,19232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15908,curation_candidate,19309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15909,curation_candidate,19380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15910,curation_candidate,19441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15911,curation_candidate,19563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15912,curation_candidate,19711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15913,curation_candidate,19814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15914,curation_candidate,19833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15915,curation_candidate,19854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15916,curation_candidate,19870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15917,curation_candidate,19956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15918,curation_candidate,20025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15919,curation_candidate,20039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15920,curation_candidate,20165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15921,curation_candidate,20237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15922,curation_candidate,20250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15923,curation_candidate,20262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15924,curation_candidate,20293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15925,curation_candidate,20304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15926,curation_candidate,20331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15927,curation_candidate,20332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15928,curation_candidate,20362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15929,curation_candidate,20390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15930,curation_candidate,20548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15931,curation_candidate,20646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15932,curation_candidate,20661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15933,curation_candidate,20773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15934,curation_candidate,20790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15935,curation_candidate,20804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15936,curation_candidate,20824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15937,curation_candidate,20905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15938,curation_candidate,20969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15939,curation_candidate,21011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15940,curation_candidate,21045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15941,curation_candidate,21070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15942,curation_candidate,21072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15943,curation_candidate,21150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15944,curation_candidate,21161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15945,curation_candidate,21162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15946,curation_candidate,21178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15947,curation_candidate,21366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15948,curation_candidate,21427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15949,curation_candidate,21484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15950,curation_candidate,21496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15951,curation_candidate,21504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15952,curation_candidate,21569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15953,curation_candidate,21640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15954,curation_candidate,21661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15955,curation_candidate,21667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15956,curation_candidate,21672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15957,curation_candidate,21713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
15958,curation_candidate,21793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15959,curation_candidate,21839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15960,curation_candidate,21984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15961,curation_candidate,22040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15962,curation_candidate,22053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15963,curation_candidate,22061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15964,curation_candidate,22088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15965,curation_candidate,22169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15966,curation_candidate,22199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15967,curation_candidate,22226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15968,curation_candidate,22286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15969,curation_candidate,22357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15970,curation_candidate,22495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15971,curation_candidate,22610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15972,curation_candidate,22702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15973,curation_candidate,22775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15974,curation_candidate,22825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15975,curation_candidate,22971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
15976,curation_candidate,23043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15977,curation_candidate,23123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15978,curation_candidate,23127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15979,curation_candidate,23140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15980,curation_candidate,23203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15981,curation_candidate,23283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15982,curation_candidate,23330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15983,curation_candidate,23473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15984,curation_candidate,23488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15985,curation_candidate,23689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15986,curation_candidate,23726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15987,curation_candidate,23877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15988,curation_candidate,23920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15989,curation_candidate,24048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15990,curation_candidate,24062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15991,curation_candidate,24111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15992,curation_candidate,24118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15993,curation_candidate,24121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
15994,curation_candidate,24205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15995,curation_candidate,24323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15996,curation_candidate,24351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
15997,curation_candidate,24466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
15998,curation_candidate,24474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
15999,curation_candidate,24831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16000,curation_candidate,24841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16001,curation_candidate,24891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16002,curation_candidate,24925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
16003,curation_candidate,24941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16004,curation_candidate,25022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16005,curation_candidate,25052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16006,curation_candidate,25179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16007,curation_candidate,25208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16008,curation_candidate,25399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16009,curation_candidate,25719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16010,curation_candidate,25734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16011,curation_candidate,25798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16012,curation_candidate,25842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16013,curation_candidate,25873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16014,curation_candidate,25877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16015,curation_candidate,25892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16016,curation_candidate,25925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16017,curation_candidate,25956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16018,curation_candidate,25967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16019,curation_candidate,26068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16020,curation_candidate,26076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16021,curation_candidate,26105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16022,curation_candidate,26118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16023,curation_candidate,26120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16024,curation_candidate,26146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
16025,curation_candidate,26187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16026,curation_candidate,26221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16027,curation_candidate,26222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16028,curation_candidate,26258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16029,curation_candidate,26263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16030,curation_candidate,26284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16031,curation_candidate,26293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16032,curation_candidate,26312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16033,curation_candidate,26313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16034,curation_candidate,26315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16035,curation_candidate,26332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16036,curation_candidate,26358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16037,curation_candidate,26359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16038,curation_candidate,26397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16039,curation_candidate,26452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16040,curation_candidate,26465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16041,curation_candidate,26484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16042,curation_candidate,26490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16043,curation_candidate,26493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16044,curation_candidate,26500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16045,curation_candidate,26548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16046,curation_candidate,26580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16047,curation_candidate,26601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16048,curation_candidate,26613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16049,curation_candidate,26624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16050,curation_candidate,26696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16051,curation_candidate,26710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16052,curation_candidate,26715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16053,curation_candidate,26743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16054,curation_candidate,26768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16055,curation_candidate,26773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16056,curation_candidate,26807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16057,curation_candidate,26830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16058,curation_candidate,26840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16059,curation_candidate,26843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16060,curation_candidate,26844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16061,curation_candidate,26896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16062,curation_candidate,26912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16063,curation_candidate,27018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16064,curation_candidate,27096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16065,curation_candidate,27152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16066,curation_candidate,27157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16067,curation_candidate,27178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16068,curation_candidate,27225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16069,curation_candidate,27246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16070,curation_candidate,27247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16071,curation_candidate,27250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16072,curation_candidate,27289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16073,curation_candidate,27290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16074,curation_candidate,27356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16075,curation_candidate,27358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16076,curation_candidate,27392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16077,curation_candidate,27405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16078,curation_candidate,27406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16079,curation_candidate,27411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16080,curation_candidate,27415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16081,curation_candidate,27417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16082,curation_candidate,27474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16083,curation_candidate,27507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16084,curation_candidate,27513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16085,curation_candidate,27530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16086,curation_candidate,27548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16087,curation_candidate,27617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16088,curation_candidate,27626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16089,curation_candidate,27632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16090,curation_candidate,27644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16091,curation_candidate,27677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16092,curation_candidate,27690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16093,curation_candidate,27863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16094,curation_candidate,27888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16095,curation_candidate,27903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16096,curation_candidate,27918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16097,curation_candidate,27968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16098,curation_candidate,27988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16099,curation_candidate,28032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16100,curation_candidate,28046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16101,curation_candidate,28073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16102,curation_candidate,28106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16103,curation_candidate,28136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16104,curation_candidate,28139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16105,curation_candidate,28187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16106,curation_candidate,28229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16107,curation_candidate,28280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16108,curation_candidate,28291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16109,curation_candidate,28318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16110,curation_candidate,28337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16111,curation_candidate,28368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16112,curation_candidate,28413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16113,curation_candidate,28476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16114,curation_candidate,28524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16115,curation_candidate,28598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16116,curation_candidate,28600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16117,curation_candidate,28633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16118,curation_candidate,28644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16119,curation_candidate,28703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16120,curation_candidate,28711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16121,curation_candidate,28776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16122,curation_candidate,28778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16123,curation_candidate,28804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16124,curation_candidate,28849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16125,curation_candidate,28862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16126,curation_candidate,28893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16127,curation_candidate,28974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16128,curation_candidate,29005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16129,curation_candidate,29011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16130,curation_candidate,29040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16131,curation_candidate,29105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16132,curation_candidate,29121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16133,curation_candidate,29131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16134,curation_candidate,29157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16135,curation_candidate,29173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16136,curation_candidate,29189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16137,curation_candidate,29219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16138,curation_candidate,29246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16139,curation_candidate,29251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16140,curation_candidate,29253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16141,curation_candidate,29315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16142,curation_candidate,29326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16143,curation_candidate,29356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16144,curation_candidate,29363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16145,curation_candidate,29401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16146,curation_candidate,29424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16147,curation_candidate,29458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16148,curation_candidate,29476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16149,curation_candidate,29491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16150,curation_candidate,29492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16151,curation_candidate,29518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16152,curation_candidate,29525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16153,curation_candidate,29560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16154,curation_candidate,29603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16155,curation_candidate,29637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16156,curation_candidate,29642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16157,curation_candidate,29645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16158,curation_candidate,29646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16159,curation_candidate,29649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16160,curation_candidate,29661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16161,curation_candidate,29682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16162,curation_candidate,29704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16163,curation_candidate,29743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16164,curation_candidate,29747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16165,curation_candidate,29756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16166,curation_candidate,29839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16167,curation_candidate,30529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16168,curation_candidate,30730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16169,curation_candidate,31022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16170,curation_candidate,31417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16171,curation_candidate,31700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16172,curation_candidate,31891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16173,curation_candidate,31997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16174,curation_candidate,32244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
16175,curation_candidate,32269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16176,curation_candidate,33059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16177,curation_candidate,33770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16178,curation_candidate,33981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16179,curation_candidate,34160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16180,curation_candidate,34187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16181,curation_candidate,34201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16182,curation_candidate,34624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16183,curation_candidate,34853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16184,curation_candidate,34867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16185,curation_candidate,34950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16186,curation_candidate,35055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16187,curation_candidate,35100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16188,curation_candidate,35116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
16189,curation_candidate,35380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16190,curation_candidate,35392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16191,curation_candidate,35509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16192,curation_candidate,35860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16193,curation_candidate,36036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16194,curation_candidate,36043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16195,curation_candidate,36679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16196,curation_candidate,36695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16197,curation_candidate,36751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16198,curation_candidate,36774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16199,curation_candidate,36776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16200,curation_candidate,36934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16201,curation_candidate,37138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16202,curation_candidate,37252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16203,curation_candidate,37282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16204,curation_candidate,37303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16205,curation_candidate,37401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16206,curation_candidate,37675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16207,curation_candidate,37985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16208,curation_candidate,38015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16209,curation_candidate,38245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16210,curation_candidate,16376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16211,curation_candidate,16384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16212,curation_candidate,16432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16213,curation_candidate,16484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
16214,curation_candidate,16495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16215,curation_candidate,16507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16216,curation_candidate,16602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16217,curation_candidate,16612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16218,curation_candidate,16639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16219,curation_candidate,16700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16220,curation_candidate,16728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16221,curation_candidate,16755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16222,curation_candidate,16788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16223,curation_candidate,16819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16224,curation_candidate,17022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16225,curation_candidate,17034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16226,curation_candidate,17050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16227,curation_candidate,17172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16228,curation_candidate,17229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16229,curation_candidate,17244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16230,curation_candidate,17260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16231,curation_candidate,17350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16232,curation_candidate,17470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16233,curation_candidate,17505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16234,curation_candidate,17516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16235,curation_candidate,17528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16236,curation_candidate,17593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16237,curation_candidate,17650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
16238,curation_candidate,17741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16239,curation_candidate,17775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16240,curation_candidate,17907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16241,curation_candidate,17921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16242,curation_candidate,18159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16243,curation_candidate,18264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16244,curation_candidate,18380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16245,curation_candidate,18429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16246,curation_candidate,18447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16247,curation_candidate,18486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16248,curation_candidate,18492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
16249,curation_candidate,18591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16250,curation_candidate,18602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16251,curation_candidate,18721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16252,curation_candidate,18738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16253,curation_candidate,18819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16254,curation_candidate,18841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16255,curation_candidate,19128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16256,curation_candidate,19205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16257,curation_candidate,19227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16258,curation_candidate,19261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16259,curation_candidate,19277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16260,curation_candidate,19440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16261,curation_candidate,19446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16262,curation_candidate,19496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16263,curation_candidate,19626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16264,curation_candidate,19654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16265,curation_candidate,19755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16266,curation_candidate,19787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16267,curation_candidate,19829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16268,curation_candidate,20012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16269,curation_candidate,20067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16270,curation_candidate,20128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16271,curation_candidate,20180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16272,curation_candidate,20202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16273,curation_candidate,20267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16274,curation_candidate,20312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16275,curation_candidate,20361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16276,curation_candidate,20408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16277,curation_candidate,20411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16278,curation_candidate,20499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16279,curation_candidate,20519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16280,curation_candidate,20694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16281,curation_candidate,20697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16282,curation_candidate,20738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16283,curation_candidate,20755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16284,curation_candidate,20798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16285,curation_candidate,20902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16286,curation_candidate,20941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16287,curation_candidate,20948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16288,curation_candidate,20987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16289,curation_candidate,20990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16290,curation_candidate,21152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16291,curation_candidate,21230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16292,curation_candidate,21323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16293,curation_candidate,21335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16294,curation_candidate,21389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16295,curation_candidate,21491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16296,curation_candidate,21547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
16297,curation_candidate,21612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16298,curation_candidate,21633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16299,curation_candidate,21668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16300,curation_candidate,21803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16301,curation_candidate,21833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16302,curation_candidate,21868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16303,curation_candidate,21934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16304,curation_candidate,21945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16305,curation_candidate,21947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16306,curation_candidate,21996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16307,curation_candidate,22030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16308,curation_candidate,22033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16309,curation_candidate,22050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16310,curation_candidate,22146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16311,curation_candidate,22184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16312,curation_candidate,22207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16313,curation_candidate,22259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16314,curation_candidate,22269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16315,curation_candidate,22342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16316,curation_candidate,22379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
16317,curation_candidate,22388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16318,curation_candidate,22408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16319,curation_candidate,22409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16320,curation_candidate,22412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16321,curation_candidate,22420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16322,curation_candidate,22464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16323,curation_candidate,22479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16324,curation_candidate,22540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16325,curation_candidate,22546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16326,curation_candidate,22582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16327,curation_candidate,22624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16328,curation_candidate,22647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16329,curation_candidate,22649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16330,curation_candidate,22759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16331,curation_candidate,22990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16332,curation_candidate,23106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16333,curation_candidate,23168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16334,curation_candidate,23192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16335,curation_candidate,23219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16336,curation_candidate,23234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16337,curation_candidate,23235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16338,curation_candidate,23316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16339,curation_candidate,23331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16340,curation_candidate,23393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16341,curation_candidate,23395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16342,curation_candidate,23430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16343,curation_candidate,23442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16344,curation_candidate,23607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16345,curation_candidate,23608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16346,curation_candidate,23670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16347,curation_candidate,23728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16348,curation_candidate,23755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16349,curation_candidate,23816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16350,curation_candidate,23821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16351,curation_candidate,23840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16352,curation_candidate,23890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16353,curation_candidate,23947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16354,curation_candidate,23971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16355,curation_candidate,24042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16356,curation_candidate,24056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16357,curation_candidate,24060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16358,curation_candidate,24110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16359,curation_candidate,24132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16360,curation_candidate,24188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16361,curation_candidate,24228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16362,curation_candidate,24330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16363,curation_candidate,24355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16364,curation_candidate,24367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16365,curation_candidate,24547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16366,curation_candidate,24677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16367,curation_candidate,24686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16368,curation_candidate,24731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16369,curation_candidate,24738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16370,curation_candidate,24772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16371,curation_candidate,24843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16372,curation_candidate,24924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16373,curation_candidate,24987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16374,curation_candidate,25136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16375,curation_candidate,25138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16376,curation_candidate,25297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16377,curation_candidate,25351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16378,curation_candidate,25430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16379,curation_candidate,25520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16380,curation_candidate,25530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16381,curation_candidate,25536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16382,curation_candidate,25611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16383,curation_candidate,25635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16384,curation_candidate,25663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16385,curation_candidate,25683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16386,curation_candidate,25781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16387,curation_candidate,25804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16388,curation_candidate,25824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16389,curation_candidate,25835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16390,curation_candidate,25849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16391,curation_candidate,25850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16392,curation_candidate,25858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16393,curation_candidate,25868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16394,curation_candidate,25870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16395,curation_candidate,25885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16396,curation_candidate,25995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16397,curation_candidate,26037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16398,curation_candidate,26061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16399,curation_candidate,26063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16400,curation_candidate,26082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16401,curation_candidate,26109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16402,curation_candidate,26151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
16403,curation_candidate,26235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16404,curation_candidate,26260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16405,curation_candidate,26266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16406,curation_candidate,26282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16407,curation_candidate,26288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16408,curation_candidate,26291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16409,curation_candidate,26323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16410,curation_candidate,26373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16411,curation_candidate,26398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16412,curation_candidate,26418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16413,curation_candidate,26438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16414,curation_candidate,26443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16415,curation_candidate,26449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16416,curation_candidate,26450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16417,curation_candidate,26456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16418,curation_candidate,26468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16419,curation_candidate,26472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16420,curation_candidate,26492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16421,curation_candidate,26508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16422,curation_candidate,26517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16423,curation_candidate,26530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16424,curation_candidate,26541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16425,curation_candidate,26610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16426,curation_candidate,26622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16427,curation_candidate,26642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16428,curation_candidate,26672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16429,curation_candidate,26681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16430,curation_candidate,26694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16431,curation_candidate,26713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16432,curation_candidate,26752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16433,curation_candidate,26772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16434,curation_candidate,26795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16435,curation_candidate,26801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16436,curation_candidate,26803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16437,curation_candidate,26831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16438,curation_candidate,26832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16439,curation_candidate,26867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16440,curation_candidate,26921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16441,curation_candidate,26936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16442,curation_candidate,26944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16443,curation_candidate,26955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16444,curation_candidate,26973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16445,curation_candidate,26997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16446,curation_candidate,27000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16447,curation_candidate,27003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16448,curation_candidate,27006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16449,curation_candidate,27024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16450,curation_candidate,27046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16451,curation_candidate,27169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16452,curation_candidate,27205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16453,curation_candidate,27236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16454,curation_candidate,27284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16455,curation_candidate,27311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16456,curation_candidate,27322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16457,curation_candidate,27328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16458,curation_candidate,27332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16459,curation_candidate,27333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16460,curation_candidate,27360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16461,curation_candidate,27365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16462,curation_candidate,27366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16463,curation_candidate,27378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16464,curation_candidate,27384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16465,curation_candidate,27428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16466,curation_candidate,27448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16467,curation_candidate,27489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16468,curation_candidate,27497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16469,curation_candidate,27538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16470,curation_candidate,27578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16471,curation_candidate,27625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16472,curation_candidate,27653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16473,curation_candidate,27660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16474,curation_candidate,27686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16475,curation_candidate,27765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16476,curation_candidate,27793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16477,curation_candidate,27796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16478,curation_candidate,27825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16479,curation_candidate,27849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16480,curation_candidate,27862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16481,curation_candidate,27867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16482,curation_candidate,27884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16483,curation_candidate,27889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16484,curation_candidate,28022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16485,curation_candidate,28036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16486,curation_candidate,28047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16487,curation_candidate,28090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16488,curation_candidate,28096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16489,curation_candidate,28101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16490,curation_candidate,28114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16491,curation_candidate,28123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16492,curation_candidate,28138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16493,curation_candidate,28171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16494,curation_candidate,28192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16495,curation_candidate,28274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16496,curation_candidate,28299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16497,curation_candidate,28325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16498,curation_candidate,28352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16499,curation_candidate,28377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16500,curation_candidate,28387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16501,curation_candidate,28388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16502,curation_candidate,28431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16503,curation_candidate,28432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16504,curation_candidate,28480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16505,curation_candidate,28490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16506,curation_candidate,28506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16507,curation_candidate,28534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16508,curation_candidate,28584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16509,curation_candidate,28603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16510,curation_candidate,28607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16511,curation_candidate,28608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16512,curation_candidate,28616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16513,curation_candidate,28730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16514,curation_candidate,28734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16515,curation_candidate,28737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16516,curation_candidate,28748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16517,curation_candidate,28750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16518,curation_candidate,28779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16519,curation_candidate,28810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16520,curation_candidate,28838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16521,curation_candidate,28872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16522,curation_candidate,28894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
16523,curation_candidate,28897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16524,curation_candidate,28910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
16525,curation_candidate,28920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16526,curation_candidate,28937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16527,curation_candidate,28954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16528,curation_candidate,28961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16529,curation_candidate,29014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16530,curation_candidate,29076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16531,curation_candidate,29144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16532,curation_candidate,29211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16533,curation_candidate,29218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16534,curation_candidate,29270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16535,curation_candidate,29276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16536,curation_candidate,29349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16537,curation_candidate,29360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16538,curation_candidate,29432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16539,curation_candidate,29435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16540,curation_candidate,29447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16541,curation_candidate,29506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16542,curation_candidate,29522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16543,curation_candidate,29571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16544,curation_candidate,29629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16545,curation_candidate,29643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16546,curation_candidate,29654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16547,curation_candidate,29672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16548,curation_candidate,29681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16549,curation_candidate,29716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16550,curation_candidate,29729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16551,curation_candidate,29748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16552,curation_candidate,29798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16553,curation_candidate,29941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16554,curation_candidate,29980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16555,curation_candidate,30037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16556,curation_candidate,30046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16557,curation_candidate,30678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16558,curation_candidate,30692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16559,curation_candidate,30707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16560,curation_candidate,30910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16561,curation_candidate,30977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16562,curation_candidate,31106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16563,curation_candidate,31570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16564,curation_candidate,31739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16565,curation_candidate,32087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16566,curation_candidate,32190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16567,curation_candidate,32678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16568,curation_candidate,32800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16569,curation_candidate,32880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16570,curation_candidate,33175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16571,curation_candidate,33589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16572,curation_candidate,33655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16573,curation_candidate,33937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16574,curation_candidate,34925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16575,curation_candidate,35063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16576,curation_candidate,35174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16577,curation_candidate,35203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16578,curation_candidate,35262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16579,curation_candidate,35395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16580,curation_candidate,35738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16581,curation_candidate,35911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16582,curation_candidate,35923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16583,curation_candidate,36192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16584,curation_candidate,36258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16585,curation_candidate,36270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16586,curation_candidate,36327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16587,curation_candidate,36343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16588,curation_candidate,36434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16589,curation_candidate,36597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16590,curation_candidate,36635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16591,curation_candidate,36780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16592,curation_candidate,36807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16593,curation_candidate,36901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16594,curation_candidate,36980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16595,curation_candidate,37106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16596,curation_candidate,37147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16597,curation_candidate,37272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16598,curation_candidate,37278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16599,curation_candidate,37343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16600,curation_candidate,37537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16601,curation_candidate,37679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16602,curation_candidate,37961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16603,curation_candidate,37963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16604,curation_candidate,37976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16605,curation_candidate,38119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16606,curation_candidate,38181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16607,curation_candidate,38243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16608,curation_candidate,16556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16609,curation_candidate,16596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16610,curation_candidate,16611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16611,curation_candidate,16615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16612,curation_candidate,16618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16613,curation_candidate,16625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16614,curation_candidate,16693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16615,curation_candidate,16701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16616,curation_candidate,16712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16617,curation_candidate,16731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16618,curation_candidate,16735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16619,curation_candidate,16747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16620,curation_candidate,16762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16621,curation_candidate,16768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16622,curation_candidate,17008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16623,curation_candidate,17065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16624,curation_candidate,17209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16625,curation_candidate,17298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16626,curation_candidate,17328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16627,curation_candidate,17430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16628,curation_candidate,17446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16629,curation_candidate,17633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16630,curation_candidate,17680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16631,curation_candidate,17715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16632,curation_candidate,17719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16633,curation_candidate,17750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16634,curation_candidate,17764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16635,curation_candidate,17781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16636,curation_candidate,17926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16637,curation_candidate,17970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16638,curation_candidate,17972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16639,curation_candidate,18177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16640,curation_candidate,18214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16641,curation_candidate,18307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16642,curation_candidate,18316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16643,curation_candidate,18417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16644,curation_candidate,18466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16645,curation_candidate,18514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16646,curation_candidate,18587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16647,curation_candidate,18606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16648,curation_candidate,18649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16649,curation_candidate,18715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16650,curation_candidate,18760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16651,curation_candidate,18771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16652,curation_candidate,18810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16653,curation_candidate,18886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16654,curation_candidate,18919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16655,curation_candidate,18921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16656,curation_candidate,19046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16657,curation_candidate,19095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16658,curation_candidate,19153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16659,curation_candidate,19202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16660,curation_candidate,19250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16661,curation_candidate,19276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16662,curation_candidate,19391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16663,curation_candidate,19400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16664,curation_candidate,19455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16665,curation_candidate,19467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16666,curation_candidate,19600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16667,curation_candidate,19620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16668,curation_candidate,19702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16669,curation_candidate,19708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16670,curation_candidate,19713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16671,curation_candidate,19836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16672,curation_candidate,19849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16673,curation_candidate,19878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16674,curation_candidate,19932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16675,curation_candidate,19946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16676,curation_candidate,19959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16677,curation_candidate,20011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16678,curation_candidate,20033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16679,curation_candidate,20088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16680,curation_candidate,20146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16681,curation_candidate,20174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16682,curation_candidate,20210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16683,curation_candidate,20212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16684,curation_candidate,20253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16685,curation_candidate,20313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16686,curation_candidate,20315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16687,curation_candidate,20345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16688,curation_candidate,20360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16689,curation_candidate,20581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16690,curation_candidate,20588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16691,curation_candidate,20621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16692,curation_candidate,20638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16693,curation_candidate,20653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16694,curation_candidate,20686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16695,curation_candidate,20754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16696,curation_candidate,20774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16697,curation_candidate,20782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16698,curation_candidate,20829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16699,curation_candidate,20871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16700,curation_candidate,20901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16701,curation_candidate,20915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16702,curation_candidate,20980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16703,curation_candidate,21037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16704,curation_candidate,21094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16705,curation_candidate,21103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16706,curation_candidate,21136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16707,curation_candidate,21177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16708,curation_candidate,21182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16709,curation_candidate,21226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16710,curation_candidate,21256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16711,curation_candidate,21310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16712,curation_candidate,21379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16713,curation_candidate,21458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16714,curation_candidate,21494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16715,curation_candidate,21624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16716,curation_candidate,21756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16717,curation_candidate,21768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16718,curation_candidate,21770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16719,curation_candidate,21776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16720,curation_candidate,21809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16721,curation_candidate,21812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16722,curation_candidate,21850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16723,curation_candidate,21855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16724,curation_candidate,22001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16725,curation_candidate,22084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16726,curation_candidate,22085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16727,curation_candidate,22086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16728,curation_candidate,22135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16729,curation_candidate,22276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16730,curation_candidate,22305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
16731,curation_candidate,22381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16732,curation_candidate,22385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16733,curation_candidate,22387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16734,curation_candidate,22407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16735,curation_candidate,22423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16736,curation_candidate,22431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16737,curation_candidate,22435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16738,curation_candidate,22514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16739,curation_candidate,22530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16740,curation_candidate,22551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16741,curation_candidate,22581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16742,curation_candidate,22600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16743,curation_candidate,22608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16744,curation_candidate,22626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16745,curation_candidate,22736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16746,curation_candidate,22757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16747,curation_candidate,22791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16748,curation_candidate,22817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16749,curation_candidate,22818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16750,curation_candidate,22942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16751,curation_candidate,22948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16752,curation_candidate,22959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16753,curation_candidate,23195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16754,curation_candidate,23226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16755,curation_candidate,23253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16756,curation_candidate,23389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16757,curation_candidate,23416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16758,curation_candidate,23474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16759,curation_candidate,23487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16760,curation_candidate,23503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16761,curation_candidate,23538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16762,curation_candidate,23571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16763,curation_candidate,23585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16764,curation_candidate,23597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16765,curation_candidate,23666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16766,curation_candidate,23707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16767,curation_candidate,23767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16768,curation_candidate,23813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16769,curation_candidate,23880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16770,curation_candidate,23910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16771,curation_candidate,23994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16772,curation_candidate,24010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16773,curation_candidate,24049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16774,curation_candidate,24122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16775,curation_candidate,24154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16776,curation_candidate,24177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16777,curation_candidate,24198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16778,curation_candidate,24326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16779,curation_candidate,24544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16780,curation_candidate,24696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16781,curation_candidate,24701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16782,curation_candidate,24724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16783,curation_candidate,24784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16784,curation_candidate,24813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16785,curation_candidate,24834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16786,curation_candidate,24844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16787,curation_candidate,24899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16788,curation_candidate,24915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16789,curation_candidate,24921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16790,curation_candidate,24923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16791,curation_candidate,25080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16792,curation_candidate,25135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16793,curation_candidate,25145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16794,curation_candidate,25168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16795,curation_candidate,25190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16796,curation_candidate,25277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16797,curation_candidate,25383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16798,curation_candidate,25463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16799,curation_candidate,25622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16800,curation_candidate,25677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16801,curation_candidate,25729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16802,curation_candidate,25756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16803,curation_candidate,25908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16804,curation_candidate,25922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16805,curation_candidate,25949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16806,curation_candidate,25975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16807,curation_candidate,25987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16808,curation_candidate,25997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16809,curation_candidate,26003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16810,curation_candidate,26004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16811,curation_candidate,26022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16812,curation_candidate,26049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16813,curation_candidate,26059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16814,curation_candidate,26070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16815,curation_candidate,26080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16816,curation_candidate,26093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16817,curation_candidate,26160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16818,curation_candidate,26167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16819,curation_candidate,26198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16820,curation_candidate,26200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16821,curation_candidate,26210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16822,curation_candidate,26231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16823,curation_candidate,26233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16824,curation_candidate,26242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16825,curation_candidate,26280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16826,curation_candidate,26295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16827,curation_candidate,26297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16828,curation_candidate,26301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16829,curation_candidate,26304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16830,curation_candidate,26306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16831,curation_candidate,26317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16832,curation_candidate,26319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16833,curation_candidate,26357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16834,curation_candidate,26402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16835,curation_candidate,26410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16836,curation_candidate,26412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16837,curation_candidate,26417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16838,curation_candidate,26435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16839,curation_candidate,26440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16840,curation_candidate,26461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16841,curation_candidate,26488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16842,curation_candidate,26503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16843,curation_candidate,26522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16844,curation_candidate,26540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16845,curation_candidate,26581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16846,curation_candidate,26593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16847,curation_candidate,26603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16848,curation_candidate,26614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16849,curation_candidate,26617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16850,curation_candidate,26618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16851,curation_candidate,26640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16852,curation_candidate,26655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16853,curation_candidate,26717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16854,curation_candidate,26747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
16855,curation_candidate,26755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16856,curation_candidate,26777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16857,curation_candidate,26781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16858,curation_candidate,26895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16859,curation_candidate,26897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16860,curation_candidate,26908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16861,curation_candidate,26916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16862,curation_candidate,26965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16863,curation_candidate,27041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16864,curation_candidate,27049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16865,curation_candidate,27062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16866,curation_candidate,27071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16867,curation_candidate,27102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16868,curation_candidate,27133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16869,curation_candidate,27224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16870,curation_candidate,27241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16871,curation_candidate,27254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16872,curation_candidate,27285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16873,curation_candidate,27288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16874,curation_candidate,27304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16875,curation_candidate,27326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16876,curation_candidate,27379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16877,curation_candidate,27383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16878,curation_candidate,27391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16879,curation_candidate,27394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16880,curation_candidate,27400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16881,curation_candidate,27401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16882,curation_candidate,27413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16883,curation_candidate,27423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16884,curation_candidate,27435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16885,curation_candidate,27512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16886,curation_candidate,27576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16887,curation_candidate,27588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16888,curation_candidate,27609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16889,curation_candidate,27647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16890,curation_candidate,27654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16891,curation_candidate,27655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16892,curation_candidate,27665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16893,curation_candidate,27670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16894,curation_candidate,27695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16895,curation_candidate,27696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16896,curation_candidate,27697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16897,curation_candidate,27698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16898,curation_candidate,27708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16899,curation_candidate,27712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16900,curation_candidate,27718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16901,curation_candidate,27719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16902,curation_candidate,27730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16903,curation_candidate,27740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16904,curation_candidate,27750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16905,curation_candidate,27779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16906,curation_candidate,27786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16907,curation_candidate,27800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16908,curation_candidate,27816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16909,curation_candidate,27829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16910,curation_candidate,27882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16911,curation_candidate,27956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16912,curation_candidate,27981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16913,curation_candidate,28029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16914,curation_candidate,28098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16915,curation_candidate,28103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16916,curation_candidate,28161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16917,curation_candidate,28177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16918,curation_candidate,28181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16919,curation_candidate,28208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16920,curation_candidate,28226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16921,curation_candidate,28227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16922,curation_candidate,28232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16923,curation_candidate,28246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16924,curation_candidate,28294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16925,curation_candidate,28306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16926,curation_candidate,28411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16927,curation_candidate,28423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16928,curation_candidate,28424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16929,curation_candidate,28543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16930,curation_candidate,28559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16931,curation_candidate,28645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16932,curation_candidate,28674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16933,curation_candidate,28679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16934,curation_candidate,28712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16935,curation_candidate,28739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16936,curation_candidate,28743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16937,curation_candidate,28784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16938,curation_candidate,28788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16939,curation_candidate,28794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16940,curation_candidate,28836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16941,curation_candidate,28840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
16942,curation_candidate,28868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16943,curation_candidate,28882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16944,curation_candidate,28889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16945,curation_candidate,28892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16946,curation_candidate,28947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16947,curation_candidate,28979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16948,curation_candidate,28980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16949,curation_candidate,29059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16950,curation_candidate,29060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16951,curation_candidate,29068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16952,curation_candidate,29087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16953,curation_candidate,29147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16954,curation_candidate,29178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16955,curation_candidate,29198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16956,curation_candidate,29207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16957,curation_candidate,29209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16958,curation_candidate,29216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16959,curation_candidate,29268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
16960,curation_candidate,29283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16961,curation_candidate,29375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16962,curation_candidate,29391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16963,curation_candidate,29409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16964,curation_candidate,29443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16965,curation_candidate,29448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16966,curation_candidate,29479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16967,curation_candidate,29605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16968,curation_candidate,29608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16969,curation_candidate,29618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16970,curation_candidate,29635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16971,curation_candidate,29666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16972,curation_candidate,29674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16973,curation_candidate,29679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16974,curation_candidate,29758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16975,curation_candidate,29824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16976,curation_candidate,29879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16977,curation_candidate,30011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16978,curation_candidate,30083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16979,curation_candidate,30119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16980,curation_candidate,30161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16981,curation_candidate,30431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16982,curation_candidate,30803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16983,curation_candidate,31074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16984,curation_candidate,31306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16985,curation_candidate,31436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16986,curation_candidate,31516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
16987,curation_candidate,32178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16988,curation_candidate,32211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16989,curation_candidate,32670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16990,curation_candidate,33164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16991,curation_candidate,33209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
16992,curation_candidate,33494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16993,curation_candidate,33584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
16994,curation_candidate,33591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16995,curation_candidate,33748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
16996,curation_candidate,33844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16997,curation_candidate,33855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
16998,curation_candidate,34202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
16999,curation_candidate,34218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17000,curation_candidate,34300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17001,curation_candidate,34833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17002,curation_candidate,35031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17003,curation_candidate,35069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17004,curation_candidate,35257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17005,curation_candidate,35323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17006,curation_candidate,35447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17007,curation_candidate,36058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17008,curation_candidate,36113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17009,curation_candidate,36174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17010,curation_candidate,36186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17011,curation_candidate,36493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17012,curation_candidate,36603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17013,curation_candidate,36629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17014,curation_candidate,36784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17015,curation_candidate,36870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17016,curation_candidate,36923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17017,curation_candidate,36936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17018,curation_candidate,36940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17019,curation_candidate,36982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17020,curation_candidate,37052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17021,curation_candidate,37326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17022,curation_candidate,37330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17023,curation_candidate,37442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17024,curation_candidate,37463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17025,curation_candidate,37504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17026,curation_candidate,37535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17027,curation_candidate,37705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17028,curation_candidate,37885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17029,curation_candidate,38013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17030,curation_candidate,38305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17031,curation_candidate,16403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17032,curation_candidate,16420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17033,curation_candidate,16444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17034,curation_candidate,16528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17035,curation_candidate,16538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17036,curation_candidate,16593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17037,curation_candidate,16606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17038,curation_candidate,16646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17039,curation_candidate,16658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17040,curation_candidate,16664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17041,curation_candidate,16685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17042,curation_candidate,16722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17043,curation_candidate,16729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17044,curation_candidate,16732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17045,curation_candidate,16746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17046,curation_candidate,16753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17047,curation_candidate,16761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17048,curation_candidate,16765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17049,curation_candidate,16771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17050,curation_candidate,16795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17051,curation_candidate,16841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17052,curation_candidate,16869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17053,curation_candidate,16872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17054,curation_candidate,17039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17055,curation_candidate,17071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17056,curation_candidate,17072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17057,curation_candidate,17099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17058,curation_candidate,17104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17059,curation_candidate,17194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17060,curation_candidate,17251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17061,curation_candidate,17257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17062,curation_candidate,17263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17063,curation_candidate,17396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17064,curation_candidate,17449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17065,curation_candidate,17711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17066,curation_candidate,17886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17067,curation_candidate,17982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17068,curation_candidate,18074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17069,curation_candidate,18095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17070,curation_candidate,18103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17071,curation_candidate,18109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17072,curation_candidate,18148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17073,curation_candidate,18198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17074,curation_candidate,18255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17075,curation_candidate,18272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17076,curation_candidate,18280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17077,curation_candidate,18338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17078,curation_candidate,18516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17079,curation_candidate,18525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17080,curation_candidate,18537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17081,curation_candidate,18621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17082,curation_candidate,18712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17083,curation_candidate,18767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17084,curation_candidate,18799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17085,curation_candidate,18817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17086,curation_candidate,18844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17087,curation_candidate,18845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17088,curation_candidate,18870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17089,curation_candidate,18981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17090,curation_candidate,18996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17091,curation_candidate,19112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17092,curation_candidate,19138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17093,curation_candidate,19175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17094,curation_candidate,19204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17095,curation_candidate,19342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17096,curation_candidate,19344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17097,curation_candidate,19346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17098,curation_candidate,19354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17099,curation_candidate,19385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17100,curation_candidate,19393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17101,curation_candidate,19420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17102,curation_candidate,19426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17103,curation_candidate,19601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17104,curation_candidate,19614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17105,curation_candidate,19799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17106,curation_candidate,19835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17107,curation_candidate,19838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17108,curation_candidate,19860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17109,curation_candidate,19875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17110,curation_candidate,19942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17111,curation_candidate,19970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17112,curation_candidate,20145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17113,curation_candidate,20149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17114,curation_candidate,20164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17115,curation_candidate,20179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
17116,curation_candidate,20257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17117,curation_candidate,20429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17118,curation_candidate,20517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17119,curation_candidate,20520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17120,curation_candidate,20555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17121,curation_candidate,20571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17122,curation_candidate,20596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17123,curation_candidate,20628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17124,curation_candidate,20630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17125,curation_candidate,20662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17126,curation_candidate,20720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17127,curation_candidate,20733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17128,curation_candidate,20827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17129,curation_candidate,20850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17130,curation_candidate,20875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17131,curation_candidate,20891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17132,curation_candidate,20892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17133,curation_candidate,20940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17134,curation_candidate,20964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17135,curation_candidate,21008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17136,curation_candidate,21055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17137,curation_candidate,21058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17138,curation_candidate,21065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17139,curation_candidate,21173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17140,curation_candidate,21198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17141,curation_candidate,21211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17142,curation_candidate,21302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17143,curation_candidate,21373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17144,curation_candidate,21459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17145,curation_candidate,21486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17146,curation_candidate,21490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17147,curation_candidate,21531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17148,curation_candidate,21537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17149,curation_candidate,21552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17150,curation_candidate,21575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17151,curation_candidate,21584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17152,curation_candidate,21641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17153,curation_candidate,21655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17154,curation_candidate,21681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17155,curation_candidate,21701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17156,curation_candidate,21715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
17157,curation_candidate,21785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17158,curation_candidate,21790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17159,curation_candidate,21797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17160,curation_candidate,21840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17161,curation_candidate,21889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17162,curation_candidate,21895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17163,curation_candidate,21950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17164,curation_candidate,21961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17165,curation_candidate,21998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17166,curation_candidate,22020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17167,curation_candidate,22137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
17168,curation_candidate,22241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17169,curation_candidate,22320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17170,curation_candidate,22329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17171,curation_candidate,22343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17172,curation_candidate,22395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17173,curation_candidate,22487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17174,curation_candidate,22588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17175,curation_candidate,22606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17176,curation_candidate,22620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17177,curation_candidate,22730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17178,curation_candidate,22766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17179,curation_candidate,22780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17180,curation_candidate,22846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17181,curation_candidate,22856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17182,curation_candidate,22867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17183,curation_candidate,22978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17184,curation_candidate,23004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17185,curation_candidate,23030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17186,curation_candidate,23036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17187,curation_candidate,23073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17188,curation_candidate,23084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17189,curation_candidate,23092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17190,curation_candidate,23105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17191,curation_candidate,23171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17192,curation_candidate,23340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17193,curation_candidate,23371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17194,curation_candidate,23414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17195,curation_candidate,23441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17196,curation_candidate,23472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17197,curation_candidate,23517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17198,curation_candidate,23727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17199,curation_candidate,23735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17200,curation_candidate,23744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17201,curation_candidate,23863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17202,curation_candidate,23873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17203,curation_candidate,24007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17204,curation_candidate,24014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17205,curation_candidate,24017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17206,curation_candidate,24019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17207,curation_candidate,24120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17208,curation_candidate,24130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17209,curation_candidate,24227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17210,curation_candidate,24301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17211,curation_candidate,24374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17212,curation_candidate,24395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17213,curation_candidate,24406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17214,curation_candidate,24434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17215,curation_candidate,24452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17216,curation_candidate,24536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17217,curation_candidate,24545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17218,curation_candidate,24564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17219,curation_candidate,24588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17220,curation_candidate,24589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17221,curation_candidate,24638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17222,curation_candidate,24647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17223,curation_candidate,24745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17224,curation_candidate,24790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17225,curation_candidate,24838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17226,curation_candidate,24920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17227,curation_candidate,24930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17228,curation_candidate,24954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17229,curation_candidate,25067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17230,curation_candidate,25089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17231,curation_candidate,25094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17232,curation_candidate,25108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17233,curation_candidate,25126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17234,curation_candidate,25176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17235,curation_candidate,25225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17236,curation_candidate,25259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17237,curation_candidate,25298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17238,curation_candidate,25400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17239,curation_candidate,25475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17240,curation_candidate,25562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17241,curation_candidate,25567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17242,curation_candidate,25576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17243,curation_candidate,25660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17244,curation_candidate,25685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17245,curation_candidate,25783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
17246,curation_candidate,25799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17247,curation_candidate,25807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17248,curation_candidate,25834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17249,curation_candidate,25914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17250,curation_candidate,25933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17251,curation_candidate,25939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17252,curation_candidate,25946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17253,curation_candidate,25981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17254,curation_candidate,25992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17255,curation_candidate,26035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17256,curation_candidate,26046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
17257,curation_candidate,26053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17258,curation_candidate,26103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17259,curation_candidate,26113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17260,curation_candidate,26117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17261,curation_candidate,26147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17262,curation_candidate,26190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17263,curation_candidate,26205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17264,curation_candidate,26264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17265,curation_candidate,26287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17266,curation_candidate,26290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17267,curation_candidate,26298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17268,curation_candidate,26308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17269,curation_candidate,26328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17270,curation_candidate,26336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17271,curation_candidate,26343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17272,curation_candidate,26423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17273,curation_candidate,26459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17274,curation_candidate,26509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17275,curation_candidate,26539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17276,curation_candidate,26554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17277,curation_candidate,26584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17278,curation_candidate,26657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17279,curation_candidate,26658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17280,curation_candidate,26667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17281,curation_candidate,26673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17282,curation_candidate,26744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17283,curation_candidate,26748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17284,curation_candidate,26749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17285,curation_candidate,26794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17286,curation_candidate,26836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17287,curation_candidate,26855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17288,curation_candidate,26876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17289,curation_candidate,26894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17290,curation_candidate,26914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17291,curation_candidate,26925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17292,curation_candidate,26938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17293,curation_candidate,26989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17294,curation_candidate,27016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17295,curation_candidate,27026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17296,curation_candidate,27027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17297,curation_candidate,27039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17298,curation_candidate,27053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17299,curation_candidate,27066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17300,curation_candidate,27098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17301,curation_candidate,27100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17302,curation_candidate,27127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17303,curation_candidate,27150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17304,curation_candidate,27252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17305,curation_candidate,27376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17306,curation_candidate,27385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17307,curation_candidate,27398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17308,curation_candidate,27456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17309,curation_candidate,27461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17310,curation_candidate,27472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17311,curation_candidate,27477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
17312,curation_candidate,27499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17313,curation_candidate,27524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17314,curation_candidate,27529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17315,curation_candidate,27532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17316,curation_candidate,27536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17317,curation_candidate,27551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17318,curation_candidate,27553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17319,curation_candidate,27560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17320,curation_candidate,27597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17321,curation_candidate,27635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17322,curation_candidate,27642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17323,curation_candidate,27668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17324,curation_candidate,27672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17325,curation_candidate,27682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17326,curation_candidate,27736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17327,curation_candidate,27737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17328,curation_candidate,27751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17329,curation_candidate,27806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17330,curation_candidate,27810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17331,curation_candidate,27811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17332,curation_candidate,27838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17333,curation_candidate,27860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17334,curation_candidate,27979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17335,curation_candidate,28012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17336,curation_candidate,28038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17337,curation_candidate,28040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17338,curation_candidate,28051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
17339,curation_candidate,28092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17340,curation_candidate,28116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17341,curation_candidate,28132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17342,curation_candidate,28164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17343,curation_candidate,28178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17344,curation_candidate,28199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17345,curation_candidate,28222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17346,curation_candidate,28240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17347,curation_candidate,28310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17348,curation_candidate,28327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17349,curation_candidate,28361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17350,curation_candidate,28372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17351,curation_candidate,28406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17352,curation_candidate,28470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17353,curation_candidate,28482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17354,curation_candidate,28535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17355,curation_candidate,28542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17356,curation_candidate,28599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17357,curation_candidate,28602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17358,curation_candidate,28632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17359,curation_candidate,28669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17360,curation_candidate,28677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17361,curation_candidate,28694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17362,curation_candidate,28745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17363,curation_candidate,28746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17364,curation_candidate,28924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17365,curation_candidate,28936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17366,curation_candidate,28967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17367,curation_candidate,28988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17368,curation_candidate,29083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17369,curation_candidate,29175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17370,curation_candidate,29197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17371,curation_candidate,29263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17372,curation_candidate,29310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17373,curation_candidate,29366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
17374,curation_candidate,29377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17375,curation_candidate,29408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17376,curation_candidate,29414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17377,curation_candidate,29594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17378,curation_candidate,29648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17379,curation_candidate,29689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17380,curation_candidate,29699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17381,curation_candidate,29712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17382,curation_candidate,29740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17383,curation_candidate,29749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17384,curation_candidate,29751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17385,curation_candidate,29771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17386,curation_candidate,29877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17387,curation_candidate,30022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17388,curation_candidate,30066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17389,curation_candidate,30096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17390,curation_candidate,30410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17391,curation_candidate,30697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17392,curation_candidate,30820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17393,curation_candidate,30911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17394,curation_candidate,30951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17395,curation_candidate,31134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17396,curation_candidate,31204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17397,curation_candidate,31361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17398,curation_candidate,31414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17399,curation_candidate,31523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17400,curation_candidate,31582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17401,curation_candidate,31667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17402,curation_candidate,32005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17403,curation_candidate,32036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17404,curation_candidate,32185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17405,curation_candidate,32567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17406,curation_candidate,32865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
17407,curation_candidate,32876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17408,curation_candidate,32905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17409,curation_candidate,33047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17410,curation_candidate,33094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17411,curation_candidate,33361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17412,curation_candidate,33529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17413,curation_candidate,33842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17414,curation_candidate,33867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17415,curation_candidate,33989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17416,curation_candidate,34092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17417,curation_candidate,34103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17418,curation_candidate,34170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17419,curation_candidate,34206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17420,curation_candidate,34285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17421,curation_candidate,34290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17422,curation_candidate,34416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17423,curation_candidate,34455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17424,curation_candidate,34550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17425,curation_candidate,34553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17426,curation_candidate,34555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17427,curation_candidate,34557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17428,curation_candidate,34591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17429,curation_candidate,34653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17430,curation_candidate,34677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17431,curation_candidate,34745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17432,curation_candidate,34904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17433,curation_candidate,34932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17434,curation_candidate,35218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17435,curation_candidate,35219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17436,curation_candidate,35242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17437,curation_candidate,35266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17438,curation_candidate,35327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17439,curation_candidate,35605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17440,curation_candidate,35630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17441,curation_candidate,35644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17442,curation_candidate,35785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17443,curation_candidate,35841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17444,curation_candidate,35878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17445,curation_candidate,35922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17446,curation_candidate,36054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17447,curation_candidate,36073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17448,curation_candidate,36094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17449,curation_candidate,36175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17450,curation_candidate,36287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17451,curation_candidate,36312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17452,curation_candidate,36359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17453,curation_candidate,36438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17454,curation_candidate,36546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17455,curation_candidate,36556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17456,curation_candidate,36602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17457,curation_candidate,36662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17458,curation_candidate,36666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17459,curation_candidate,36777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
17460,curation_candidate,36794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17461,curation_candidate,36819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17462,curation_candidate,36868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17463,curation_candidate,36922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17464,curation_candidate,36924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17465,curation_candidate,36974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17466,curation_candidate,37051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17467,curation_candidate,37263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17468,curation_candidate,37266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
17469,curation_candidate,37293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17470,curation_candidate,37507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17471,curation_candidate,37850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17472,curation_candidate,37991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17473,curation_candidate,38054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17474,curation_candidate,38141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17475,curation_candidate,38142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17476,curation_candidate,38197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17477,curation_candidate,16451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17478,curation_candidate,16475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17479,curation_candidate,16502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17480,curation_candidate,16523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17481,curation_candidate,16750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17482,curation_candidate,16754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17483,curation_candidate,16773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17484,curation_candidate,16847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17485,curation_candidate,16855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17486,curation_candidate,16864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17487,curation_candidate,16895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17488,curation_candidate,16909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17489,curation_candidate,16918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17490,curation_candidate,16927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17491,curation_candidate,16929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17492,curation_candidate,16933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17493,curation_candidate,16940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17494,curation_candidate,16957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17495,curation_candidate,16979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17496,curation_candidate,17101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17497,curation_candidate,17184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17498,curation_candidate,17187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17499,curation_candidate,17222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17500,curation_candidate,17227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17501,curation_candidate,17261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17502,curation_candidate,17272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17503,curation_candidate,17346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17504,curation_candidate,17398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17505,curation_candidate,17416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17506,curation_candidate,17417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17507,curation_candidate,17421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17508,curation_candidate,17423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17509,curation_candidate,17426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17510,curation_candidate,17520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17511,curation_candidate,17686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17512,curation_candidate,17713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17513,curation_candidate,17730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17514,curation_candidate,17835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17515,curation_candidate,17837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17516,curation_candidate,17848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17517,curation_candidate,17859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17518,curation_candidate,17929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17519,curation_candidate,17984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17520,curation_candidate,17990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17521,curation_candidate,18033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17522,curation_candidate,18066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17523,curation_candidate,18068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17524,curation_candidate,18112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17525,curation_candidate,18113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17526,curation_candidate,18240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17527,curation_candidate,18258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17528,curation_candidate,18292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17529,curation_candidate,18309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17530,curation_candidate,18340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17531,curation_candidate,18366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17532,curation_candidate,18368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17533,curation_candidate,18386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17534,curation_candidate,18394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17535,curation_candidate,18475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17536,curation_candidate,18509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17537,curation_candidate,18521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17538,curation_candidate,18564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17539,curation_candidate,18583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17540,curation_candidate,18611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17541,curation_candidate,18743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17542,curation_candidate,18805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17543,curation_candidate,18847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17544,curation_candidate,18854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17545,curation_candidate,18958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17546,curation_candidate,18979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17547,curation_candidate,19012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17548,curation_candidate,19155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17549,curation_candidate,19187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17550,curation_candidate,19209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17551,curation_candidate,19286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17552,curation_candidate,19298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17553,curation_candidate,19399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17554,curation_candidate,19414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17555,curation_candidate,19469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17556,curation_candidate,19553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17557,curation_candidate,19561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17558,curation_candidate,19617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17559,curation_candidate,19645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17560,curation_candidate,19768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17561,curation_candidate,19776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17562,curation_candidate,19971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17563,curation_candidate,19984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17564,curation_candidate,19989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17565,curation_candidate,20053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17566,curation_candidate,20064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17567,curation_candidate,20091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17568,curation_candidate,20101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17569,curation_candidate,20122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17570,curation_candidate,20254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17571,curation_candidate,20447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17572,curation_candidate,20469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17573,curation_candidate,20483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17574,curation_candidate,20501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17575,curation_candidate,20526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17576,curation_candidate,20559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17577,curation_candidate,20575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17578,curation_candidate,20636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17579,curation_candidate,20642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17580,curation_candidate,20682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17581,curation_candidate,20766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17582,curation_candidate,20768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17583,curation_candidate,20770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17584,curation_candidate,20778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
17585,curation_candidate,20779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17586,curation_candidate,20865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17587,curation_candidate,20916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17588,curation_candidate,20931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17589,curation_candidate,20970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17590,curation_candidate,20972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17591,curation_candidate,20979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17592,curation_candidate,21047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17593,curation_candidate,21062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17594,curation_candidate,21073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17595,curation_candidate,21088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17596,curation_candidate,21108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17597,curation_candidate,21125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17598,curation_candidate,21159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17599,curation_candidate,21190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17600,curation_candidate,21204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17601,curation_candidate,21215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17602,curation_candidate,21219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17603,curation_candidate,21306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17604,curation_candidate,21351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17605,curation_candidate,21383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17606,curation_candidate,21401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17607,curation_candidate,21437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17608,curation_candidate,21542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17609,curation_candidate,21561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
17610,curation_candidate,21589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17611,curation_candidate,21596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17612,curation_candidate,21644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17613,curation_candidate,21781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17614,curation_candidate,21928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17615,curation_candidate,21933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17616,curation_candidate,22038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17617,curation_candidate,22087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17618,curation_candidate,22149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17619,curation_candidate,22212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17620,curation_candidate,22250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17621,curation_candidate,22277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17622,curation_candidate,22321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17623,curation_candidate,22365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17624,curation_candidate,22432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17625,curation_candidate,22442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17626,curation_candidate,22448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17627,curation_candidate,22490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17628,curation_candidate,22543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17629,curation_candidate,22591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17630,curation_candidate,22629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17631,curation_candidate,22637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17632,curation_candidate,22646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17633,curation_candidate,22675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17634,curation_candidate,22714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17635,curation_candidate,22848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17636,curation_candidate,22912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17637,curation_candidate,22917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17638,curation_candidate,23028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17639,curation_candidate,23061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17640,curation_candidate,23155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17641,curation_candidate,23232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17642,curation_candidate,23250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17643,curation_candidate,23265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17644,curation_candidate,23272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17645,curation_candidate,23291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17646,curation_candidate,23405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17647,curation_candidate,23438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17648,curation_candidate,23466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17649,curation_candidate,23544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17650,curation_candidate,23561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17651,curation_candidate,23575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17652,curation_candidate,23587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17653,curation_candidate,23600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17654,curation_candidate,23609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17655,curation_candidate,23640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17656,curation_candidate,23712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17657,curation_candidate,23762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17658,curation_candidate,23779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17659,curation_candidate,23886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17660,curation_candidate,24013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17661,curation_candidate,24043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17662,curation_candidate,24088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17663,curation_candidate,24148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17664,curation_candidate,24289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17665,curation_candidate,24338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17666,curation_candidate,24385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17667,curation_candidate,24409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17668,curation_candidate,24453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17669,curation_candidate,24496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17670,curation_candidate,24517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17671,curation_candidate,24534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17672,curation_candidate,24645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17673,curation_candidate,24662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17674,curation_candidate,24663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17675,curation_candidate,24839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17676,curation_candidate,24848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17677,curation_candidate,24901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17678,curation_candidate,24952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17679,curation_candidate,24971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17680,curation_candidate,25025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17681,curation_candidate,25229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17682,curation_candidate,25255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17683,curation_candidate,25273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17684,curation_candidate,25359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17685,curation_candidate,25419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17686,curation_candidate,25512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17687,curation_candidate,25531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17688,curation_candidate,25540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17689,curation_candidate,25607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17690,curation_candidate,25813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17691,curation_candidate,25827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17692,curation_candidate,25844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17693,curation_candidate,25881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17694,curation_candidate,25882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17695,curation_candidate,25883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17696,curation_candidate,25890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17697,curation_candidate,25916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17698,curation_candidate,25957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17699,curation_candidate,25961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17700,curation_candidate,25985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17701,curation_candidate,26006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17702,curation_candidate,26009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17703,curation_candidate,26017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17704,curation_candidate,26040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17705,curation_candidate,26115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17706,curation_candidate,26126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17707,curation_candidate,26191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17708,curation_candidate,26203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17709,curation_candidate,26285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17710,curation_candidate,26289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17711,curation_candidate,26335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17712,curation_candidate,26346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17713,curation_candidate,26439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17714,curation_candidate,26470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17715,curation_candidate,26473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17716,curation_candidate,26497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17717,curation_candidate,26568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17718,curation_candidate,26573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
17719,curation_candidate,26585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17720,curation_candidate,26646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17721,curation_candidate,26674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17722,curation_candidate,26675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17723,curation_candidate,26767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17724,curation_candidate,26813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17725,curation_candidate,26815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17726,curation_candidate,26822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17727,curation_candidate,26905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17728,curation_candidate,26910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17729,curation_candidate,26913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17730,curation_candidate,26937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17731,curation_candidate,26939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17732,curation_candidate,26966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17733,curation_candidate,26993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17734,curation_candidate,27063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17735,curation_candidate,27093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17736,curation_candidate,27138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17737,curation_candidate,27213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17738,curation_candidate,27221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17739,curation_candidate,27244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17740,curation_candidate,27274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17741,curation_candidate,27330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17742,curation_candidate,27334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17743,curation_candidate,27353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17744,curation_candidate,27367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17745,curation_candidate,27414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17746,curation_candidate,27438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17747,curation_candidate,27464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17748,curation_candidate,27522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17749,curation_candidate,27542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17750,curation_candidate,27550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17751,curation_candidate,27565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17752,curation_candidate,27583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17753,curation_candidate,27591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17754,curation_candidate,27663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17755,curation_candidate,27706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17756,curation_candidate,27709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17757,curation_candidate,27741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17758,curation_candidate,27758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17759,curation_candidate,27830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17760,curation_candidate,27865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17761,curation_candidate,27866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17762,curation_candidate,27891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17763,curation_candidate,27910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17764,curation_candidate,27919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17765,curation_candidate,27927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17766,curation_candidate,27939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17767,curation_candidate,27969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17768,curation_candidate,27984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17769,curation_candidate,27999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17770,curation_candidate,28023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17771,curation_candidate,28044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17772,curation_candidate,28056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17773,curation_candidate,28079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17774,curation_candidate,28081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17775,curation_candidate,28094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17776,curation_candidate,28108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17777,curation_candidate,28124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17778,curation_candidate,28127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17779,curation_candidate,28128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17780,curation_candidate,28133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17781,curation_candidate,28135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17782,curation_candidate,28145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17783,curation_candidate,28176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17784,curation_candidate,28197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17785,curation_candidate,28200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17786,curation_candidate,28206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17787,curation_candidate,28207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17788,curation_candidate,28219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17789,curation_candidate,28287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17790,curation_candidate,28309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17791,curation_candidate,28373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17792,curation_candidate,28437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17793,curation_candidate,28518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17794,curation_candidate,28521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17795,curation_candidate,28606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17796,curation_candidate,28627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17797,curation_candidate,28637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17798,curation_candidate,28680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
17799,curation_candidate,28685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17800,curation_candidate,28729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17801,curation_candidate,28766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17802,curation_candidate,28813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17803,curation_candidate,28888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17804,curation_candidate,28891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17805,curation_candidate,28919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17806,curation_candidate,28989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17807,curation_candidate,29013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17808,curation_candidate,29024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17809,curation_candidate,29031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17810,curation_candidate,29065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17811,curation_candidate,29112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17812,curation_candidate,29132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17813,curation_candidate,29138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17814,curation_candidate,29154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17815,curation_candidate,29162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17816,curation_candidate,29169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17817,curation_candidate,29243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17818,curation_candidate,29317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17819,curation_candidate,29327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17820,curation_candidate,29411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17821,curation_candidate,29453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17822,curation_candidate,29457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17823,curation_candidate,29461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17824,curation_candidate,29485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17825,curation_candidate,29488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17826,curation_candidate,29495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17827,curation_candidate,29499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17828,curation_candidate,29508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17829,curation_candidate,29562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17830,curation_candidate,29577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17831,curation_candidate,29578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17832,curation_candidate,29676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17833,curation_candidate,29723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17834,curation_candidate,29778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17835,curation_candidate,29812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17836,curation_candidate,29816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17837,curation_candidate,29852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17838,curation_candidate,29881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17839,curation_candidate,29940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17840,curation_candidate,30015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17841,curation_candidate,30099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17842,curation_candidate,30124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17843,curation_candidate,30316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17844,curation_candidate,30425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17845,curation_candidate,30593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17846,curation_candidate,30703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17847,curation_candidate,31186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17848,curation_candidate,31466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17849,curation_candidate,31518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17850,curation_candidate,31668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17851,curation_candidate,31966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17852,curation_candidate,31982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17853,curation_candidate,31987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17854,curation_candidate,32018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17855,curation_candidate,32065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17856,curation_candidate,32239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17857,curation_candidate,32392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17858,curation_candidate,32462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17859,curation_candidate,32539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17860,curation_candidate,32716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17861,curation_candidate,32814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17862,curation_candidate,32828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17863,curation_candidate,33108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17864,curation_candidate,33379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17865,curation_candidate,33507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17866,curation_candidate,33583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17867,curation_candidate,33792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17868,curation_candidate,33894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17869,curation_candidate,33912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17870,curation_candidate,33993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17871,curation_candidate,34011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17872,curation_candidate,34013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17873,curation_candidate,34032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17874,curation_candidate,34074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17875,curation_candidate,34111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17876,curation_candidate,34114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17877,curation_candidate,34118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17878,curation_candidate,34154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17879,curation_candidate,34257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17880,curation_candidate,34422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17881,curation_candidate,34490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17882,curation_candidate,34603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17883,curation_candidate,34604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17884,curation_candidate,34674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17885,curation_candidate,34748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17886,curation_candidate,34750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17887,curation_candidate,34781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17888,curation_candidate,34826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17889,curation_candidate,34828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17890,curation_candidate,34917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17891,curation_candidate,35005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17892,curation_candidate,35064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17893,curation_candidate,35084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17894,curation_candidate,35114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17895,curation_candidate,35119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17896,curation_candidate,35281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17897,curation_candidate,35542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17898,curation_candidate,35602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17899,curation_candidate,35730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17900,curation_candidate,35751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17901,curation_candidate,35755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17902,curation_candidate,35767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17903,curation_candidate,35895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17904,curation_candidate,35920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17905,curation_candidate,35950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17906,curation_candidate,36019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17907,curation_candidate,36047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17908,curation_candidate,36063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17909,curation_candidate,36082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17910,curation_candidate,36137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17911,curation_candidate,36203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17912,curation_candidate,36265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17913,curation_candidate,36303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17914,curation_candidate,36330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17915,curation_candidate,36340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17916,curation_candidate,36348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17917,curation_candidate,36470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17918,curation_candidate,36471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17919,curation_candidate,36498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17920,curation_candidate,36525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17921,curation_candidate,36560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17922,curation_candidate,36638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17923,curation_candidate,36657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17924,curation_candidate,36691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17925,curation_candidate,36694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17926,curation_candidate,36717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17927,curation_candidate,36773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
17928,curation_candidate,36799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17929,curation_candidate,36821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17930,curation_candidate,36828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17931,curation_candidate,36836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17932,curation_candidate,36874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17933,curation_candidate,36883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17934,curation_candidate,36910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17935,curation_candidate,36925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17936,curation_candidate,36930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17937,curation_candidate,36957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17938,curation_candidate,36979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17939,curation_candidate,36981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17940,curation_candidate,37025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17941,curation_candidate,37027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17942,curation_candidate,37063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17943,curation_candidate,37065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17944,curation_candidate,37097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17945,curation_candidate,37280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17946,curation_candidate,37474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17947,curation_candidate,37550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17948,curation_candidate,37691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17949,curation_candidate,37717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17950,curation_candidate,38106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17951,curation_candidate,38125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17952,curation_candidate,38158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17953,curation_candidate,38198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17954,curation_candidate,38216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17955,curation_candidate,38238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17956,curation_candidate,38246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
17957,curation_candidate,16524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17958,curation_candidate,16527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17959,curation_candidate,16534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17960,curation_candidate,16630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17961,curation_candidate,16636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17962,curation_candidate,16671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17963,curation_candidate,16714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17964,curation_candidate,16726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17965,curation_candidate,16727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17966,curation_candidate,16741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17967,curation_candidate,16780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17968,curation_candidate,16845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17969,curation_candidate,16856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17970,curation_candidate,16886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17971,curation_candidate,16928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17972,curation_candidate,16963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17973,curation_candidate,16965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17974,curation_candidate,17041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17975,curation_candidate,17057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17976,curation_candidate,17108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17977,curation_candidate,17144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17978,curation_candidate,17151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17979,curation_candidate,17153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17980,curation_candidate,17182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17981,curation_candidate,17220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17982,curation_candidate,17324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17983,curation_candidate,17340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17984,curation_candidate,17371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
17985,curation_candidate,17463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17986,curation_candidate,17467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17987,curation_candidate,17524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17988,curation_candidate,17598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17989,curation_candidate,17652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17990,curation_candidate,17666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17991,curation_candidate,17696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
17992,curation_candidate,17706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17993,curation_candidate,17755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17994,curation_candidate,17801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17995,curation_candidate,17814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
17996,curation_candidate,17836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17997,curation_candidate,17851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17998,curation_candidate,17860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
17999,curation_candidate,17868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18000,curation_candidate,17875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18001,curation_candidate,17909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18002,curation_candidate,17968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18003,curation_candidate,18072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18004,curation_candidate,18195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18005,curation_candidate,18206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18006,curation_candidate,18259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18007,curation_candidate,18306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18008,curation_candidate,18323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18009,curation_candidate,18337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18010,curation_candidate,18357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18011,curation_candidate,18408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18012,curation_candidate,18464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18013,curation_candidate,18470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18014,curation_candidate,18527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18015,curation_candidate,18539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18016,curation_candidate,18626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18017,curation_candidate,18711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18018,curation_candidate,18716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18019,curation_candidate,18752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18020,curation_candidate,18764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18021,curation_candidate,18807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18022,curation_candidate,18815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18023,curation_candidate,18822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18024,curation_candidate,18835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18025,curation_candidate,18864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18026,curation_candidate,18903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18027,curation_candidate,18912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18028,curation_candidate,18930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18029,curation_candidate,19084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18030,curation_candidate,19123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18031,curation_candidate,19170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18032,curation_candidate,19213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18033,curation_candidate,19239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18034,curation_candidate,19258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18035,curation_candidate,19264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18036,curation_candidate,19292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18037,curation_candidate,19325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18038,curation_candidate,19384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18039,curation_candidate,19389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18040,curation_candidate,19398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18041,curation_candidate,19434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18042,curation_candidate,19459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18043,curation_candidate,19473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18044,curation_candidate,19494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18045,curation_candidate,19586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18046,curation_candidate,19610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18047,curation_candidate,19649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18048,curation_candidate,19748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18049,curation_candidate,19769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18050,curation_candidate,19783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18051,curation_candidate,19789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18052,curation_candidate,19877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18053,curation_candidate,19881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18054,curation_candidate,19888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18055,curation_candidate,19899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18056,curation_candidate,19910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18057,curation_candidate,19962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18058,curation_candidate,19972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18059,curation_candidate,20092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18060,curation_candidate,20109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18061,curation_candidate,20111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18062,curation_candidate,20121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18063,curation_candidate,20135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18064,curation_candidate,20199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18065,curation_candidate,20275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18066,curation_candidate,20290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18067,curation_candidate,20358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18068,curation_candidate,20427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18069,curation_candidate,20462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18070,curation_candidate,20485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18071,curation_candidate,20505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18072,curation_candidate,20525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18073,curation_candidate,20527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18074,curation_candidate,20539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18075,curation_candidate,20576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18076,curation_candidate,20578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18077,curation_candidate,20599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18078,curation_candidate,20687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18079,curation_candidate,20700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18080,curation_candidate,20718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18081,curation_candidate,20741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18082,curation_candidate,20747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18083,curation_candidate,20751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18084,curation_candidate,20752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18085,curation_candidate,20843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18086,curation_candidate,20945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18087,curation_candidate,20965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18088,curation_candidate,21031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18089,curation_candidate,21235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18090,curation_candidate,21300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18091,curation_candidate,21314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18092,curation_candidate,21324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18093,curation_candidate,21331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18094,curation_candidate,21338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18095,curation_candidate,21441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18096,curation_candidate,21464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18097,curation_candidate,21470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18098,curation_candidate,21513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18099,curation_candidate,21517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18100,curation_candidate,21528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18101,curation_candidate,21603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18102,curation_candidate,21611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18103,curation_candidate,21651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18104,curation_candidate,21709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18105,curation_candidate,21712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18106,curation_candidate,21723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18107,curation_candidate,21767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18108,curation_candidate,21794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18109,curation_candidate,21796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18110,curation_candidate,21816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18111,curation_candidate,21828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18112,curation_candidate,21831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18113,curation_candidate,21872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18114,curation_candidate,21919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18115,curation_candidate,21995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18116,curation_candidate,22049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18117,curation_candidate,22134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18118,curation_candidate,22218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18119,curation_candidate,22235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18120,curation_candidate,22330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18121,curation_candidate,22361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18122,curation_candidate,22367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18123,curation_candidate,22369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18124,curation_candidate,22375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18125,curation_candidate,22417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18126,curation_candidate,22471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18127,curation_candidate,22563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18128,curation_candidate,22633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18129,curation_candidate,22669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18130,curation_candidate,22671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18131,curation_candidate,22683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18132,curation_candidate,22691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18133,curation_candidate,22704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18134,curation_candidate,22717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18135,curation_candidate,22731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18136,curation_candidate,22760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18137,curation_candidate,22784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18138,curation_candidate,22827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18139,curation_candidate,22834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18140,curation_candidate,22980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18141,curation_candidate,22996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18142,curation_candidate,23003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18143,curation_candidate,23029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18144,curation_candidate,23041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18145,curation_candidate,23144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18146,curation_candidate,23199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18147,curation_candidate,23200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18148,curation_candidate,23206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18149,curation_candidate,23344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18150,curation_candidate,23351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18151,curation_candidate,23421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18152,curation_candidate,23422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18153,curation_candidate,23463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18154,curation_candidate,23485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18155,curation_candidate,23577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18156,curation_candidate,23579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18157,curation_candidate,23644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18158,curation_candidate,23662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18159,curation_candidate,23739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18160,curation_candidate,23773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18161,curation_candidate,23791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18162,curation_candidate,23802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18163,curation_candidate,23805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18164,curation_candidate,23839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18165,curation_candidate,23849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18166,curation_candidate,23853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18167,curation_candidate,23865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18168,curation_candidate,23891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18169,curation_candidate,24087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18170,curation_candidate,24169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18171,curation_candidate,24173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18172,curation_candidate,24190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
18173,curation_candidate,24245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18174,curation_candidate,24386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18175,curation_candidate,24398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18176,curation_candidate,24414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18177,curation_candidate,24420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18178,curation_candidate,24427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18179,curation_candidate,24437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18180,curation_candidate,24501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18181,curation_candidate,24526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18182,curation_candidate,24557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18183,curation_candidate,24610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18184,curation_candidate,24615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18185,curation_candidate,24652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18186,curation_candidate,24655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18187,curation_candidate,24688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18188,curation_candidate,24723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18189,curation_candidate,24770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
18190,curation_candidate,24777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18191,curation_candidate,24810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18192,curation_candidate,24858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18193,curation_candidate,24917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18194,curation_candidate,24990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18195,curation_candidate,25048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18196,curation_candidate,25110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18197,curation_candidate,25115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18198,curation_candidate,25186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18199,curation_candidate,25191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18200,curation_candidate,25256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18201,curation_candidate,25330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18202,curation_candidate,25334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18203,curation_candidate,25358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18204,curation_candidate,25378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18205,curation_candidate,25382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18206,curation_candidate,25386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18207,curation_candidate,25473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18208,curation_candidate,25511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18209,curation_candidate,25749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18210,curation_candidate,25855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18211,curation_candidate,25889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18212,curation_candidate,25905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18213,curation_candidate,25906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18214,curation_candidate,25972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18215,curation_candidate,25986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18216,curation_candidate,26019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18217,curation_candidate,26029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18218,curation_candidate,26054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18219,curation_candidate,26067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18220,curation_candidate,26069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18221,curation_candidate,26087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18222,curation_candidate,26100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18223,curation_candidate,26132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18224,curation_candidate,26135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18225,curation_candidate,26144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18226,curation_candidate,26215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18227,curation_candidate,26248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18228,curation_candidate,26273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18229,curation_candidate,26318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18230,curation_candidate,26322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18231,curation_candidate,26333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18232,curation_candidate,26361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18233,curation_candidate,26406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18234,curation_candidate,26429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18235,curation_candidate,26463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18236,curation_candidate,26527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18237,curation_candidate,26582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18238,curation_candidate,26686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18239,curation_candidate,26702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18240,curation_candidate,26703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18241,curation_candidate,26726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18242,curation_candidate,26826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18243,curation_candidate,26829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18244,curation_candidate,26853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18245,curation_candidate,26942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18246,curation_candidate,26957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18247,curation_candidate,26971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18248,curation_candidate,26972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18249,curation_candidate,27013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18250,curation_candidate,27058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18251,curation_candidate,27059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18252,curation_candidate,27131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18253,curation_candidate,27162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18254,curation_candidate,27170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18255,curation_candidate,27259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18256,curation_candidate,27265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18257,curation_candidate,27276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18258,curation_candidate,27327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18259,curation_candidate,27375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18260,curation_candidate,27479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18261,curation_candidate,27492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18262,curation_candidate,27514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18263,curation_candidate,27570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18264,curation_candidate,27613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18265,curation_candidate,27720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18266,curation_candidate,27782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18267,curation_candidate,27791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18268,curation_candidate,27794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18269,curation_candidate,27795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18270,curation_candidate,27814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18271,curation_candidate,27854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18272,curation_candidate,27913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18273,curation_candidate,27915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18274,curation_candidate,27937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18275,curation_candidate,27952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18276,curation_candidate,27965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18277,curation_candidate,27975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18278,curation_candidate,27980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18279,curation_candidate,27990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18280,curation_candidate,28000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18281,curation_candidate,28026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18282,curation_candidate,28060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18283,curation_candidate,28061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18284,curation_candidate,28095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18285,curation_candidate,28117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18286,curation_candidate,28129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18287,curation_candidate,28148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18288,curation_candidate,28151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18289,curation_candidate,28152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18290,curation_candidate,28160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18291,curation_candidate,28205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18292,curation_candidate,28211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18293,curation_candidate,28214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18294,curation_candidate,28215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18295,curation_candidate,28224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18296,curation_candidate,28252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18297,curation_candidate,28256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18298,curation_candidate,28264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18299,curation_candidate,28268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18300,curation_candidate,28285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18301,curation_candidate,28313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18302,curation_candidate,28348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18303,curation_candidate,28357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
18304,curation_candidate,28392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18305,curation_candidate,28429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18306,curation_candidate,28444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18307,curation_candidate,28466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18308,curation_candidate,28495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18309,curation_candidate,28497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18310,curation_candidate,28527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18311,curation_candidate,28568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18312,curation_candidate,28595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18313,curation_candidate,28601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18314,curation_candidate,28672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18315,curation_candidate,28682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
18316,curation_candidate,28789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18317,curation_candidate,28825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18318,curation_candidate,28839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18319,curation_candidate,28913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18320,curation_candidate,28941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18321,curation_candidate,28973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18322,curation_candidate,29001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18323,curation_candidate,29080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18324,curation_candidate,29126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18325,curation_candidate,29160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18326,curation_candidate,29314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18327,curation_candidate,29322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18328,curation_candidate,29343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18329,curation_candidate,29362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18330,curation_candidate,29367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18331,curation_candidate,29374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18332,curation_candidate,29399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18333,curation_candidate,29501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18334,curation_candidate,29541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18335,curation_candidate,29557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18336,curation_candidate,29673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18337,curation_candidate,29683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18338,curation_candidate,29688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18339,curation_candidate,29834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18340,curation_candidate,29926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18341,curation_candidate,30049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18342,curation_candidate,30103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18343,curation_candidate,30106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18344,curation_candidate,30244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18345,curation_candidate,30308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18346,curation_candidate,30465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18347,curation_candidate,30502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18348,curation_candidate,30531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18349,curation_candidate,30536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18350,curation_candidate,30641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18351,curation_candidate,30761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18352,curation_candidate,30813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18353,curation_candidate,30846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18354,curation_candidate,31008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18355,curation_candidate,31215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18356,curation_candidate,31421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18357,curation_candidate,31524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18358,curation_candidate,31526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18359,curation_candidate,31583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18360,curation_candidate,31643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18361,curation_candidate,31790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18362,curation_candidate,32088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18363,curation_candidate,32117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18364,curation_candidate,32133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18365,curation_candidate,32278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18366,curation_candidate,32409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18367,curation_candidate,32512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18368,curation_candidate,32620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18369,curation_candidate,32621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18370,curation_candidate,32737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18371,curation_candidate,32759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18372,curation_candidate,32847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18373,curation_candidate,33035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18374,curation_candidate,33078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18375,curation_candidate,33246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18376,curation_candidate,33338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18377,curation_candidate,33661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18378,curation_candidate,33667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18379,curation_candidate,33769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18380,curation_candidate,33824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18381,curation_candidate,33955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18382,curation_candidate,33990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18383,curation_candidate,34020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18384,curation_candidate,34040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18385,curation_candidate,34078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
18386,curation_candidate,34203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18387,curation_candidate,34234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18388,curation_candidate,34267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18389,curation_candidate,34273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18390,curation_candidate,34504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18391,curation_candidate,34577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18392,curation_candidate,34766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18393,curation_candidate,34769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18394,curation_candidate,34794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18395,curation_candidate,34814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18396,curation_candidate,35011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18397,curation_candidate,35079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18398,curation_candidate,35101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18399,curation_candidate,35153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18400,curation_candidate,35189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18401,curation_candidate,35200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18402,curation_candidate,35207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18403,curation_candidate,35282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18404,curation_candidate,35295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18405,curation_candidate,35444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18406,curation_candidate,35477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18407,curation_candidate,35484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18408,curation_candidate,35530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18409,curation_candidate,35600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18410,curation_candidate,35661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18411,curation_candidate,35662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18412,curation_candidate,35701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18413,curation_candidate,35726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18414,curation_candidate,35760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18415,curation_candidate,35769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18416,curation_candidate,35776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18417,curation_candidate,35786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18418,curation_candidate,35817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18419,curation_candidate,35907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18420,curation_candidate,35951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18421,curation_candidate,35952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18422,curation_candidate,35960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18423,curation_candidate,35961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18424,curation_candidate,36048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18425,curation_candidate,36074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18426,curation_candidate,36081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18427,curation_candidate,36130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
18428,curation_candidate,36160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18429,curation_candidate,36173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18430,curation_candidate,36195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18431,curation_candidate,36222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18432,curation_candidate,36288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18433,curation_candidate,36301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18434,curation_candidate,36341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18435,curation_candidate,36347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18436,curation_candidate,36413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18437,curation_candidate,36515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18438,curation_candidate,36529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18439,curation_candidate,36598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18440,curation_candidate,36642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18441,curation_candidate,36669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18442,curation_candidate,36692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18443,curation_candidate,36757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18444,curation_candidate,36942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18445,curation_candidate,36976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18446,curation_candidate,37012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18447,curation_candidate,37098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18448,curation_candidate,37104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18449,curation_candidate,37191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18450,curation_candidate,37265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18451,curation_candidate,37311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18452,curation_candidate,37383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18453,curation_candidate,37402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18454,curation_candidate,37466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18455,curation_candidate,37513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18456,curation_candidate,37573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18457,curation_candidate,37704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18458,curation_candidate,37719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18459,curation_candidate,37749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18460,curation_candidate,37856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18461,curation_candidate,38037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18462,curation_candidate,38092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18463,curation_candidate,38159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18464,curation_candidate,38160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18465,curation_candidate,38182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18466,curation_candidate,38191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18467,curation_candidate,38215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18468,curation_candidate,38244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18469,curation_candidate,38257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18470,curation_candidate,38308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18471,curation_candidate,16359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18472,curation_candidate,16423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18473,curation_candidate,16529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18474,curation_candidate,16644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18475,curation_candidate,16690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18476,curation_candidate,16694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18477,curation_candidate,16784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18478,curation_candidate,16823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18479,curation_candidate,16858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18480,curation_candidate,16910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18481,curation_candidate,17001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18482,curation_candidate,17053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18483,curation_candidate,17093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18484,curation_candidate,17097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18485,curation_candidate,17100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18486,curation_candidate,17253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18487,curation_candidate,17281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18488,curation_candidate,17305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18489,curation_candidate,17436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18490,curation_candidate,17452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18491,curation_candidate,17532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18492,curation_candidate,17622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18493,curation_candidate,17644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18494,curation_candidate,17676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18495,curation_candidate,17754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18496,curation_candidate,17766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18497,curation_candidate,17786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18498,curation_candidate,17812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18499,curation_candidate,17827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18500,curation_candidate,17857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18501,curation_candidate,17863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18502,curation_candidate,17953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18503,curation_candidate,18010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18504,curation_candidate,18025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18505,curation_candidate,18028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18506,curation_candidate,18092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18507,curation_candidate,18139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18508,curation_candidate,18183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18509,curation_candidate,18231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18510,curation_candidate,18270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18511,curation_candidate,18320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18512,curation_candidate,18329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18513,curation_candidate,18361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18514,curation_candidate,18370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18515,curation_candidate,18377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18516,curation_candidate,18409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18517,curation_candidate,18430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18518,curation_candidate,18448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18519,curation_candidate,18459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18520,curation_candidate,18481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18521,curation_candidate,18510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18522,curation_candidate,18531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18523,curation_candidate,18533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18524,curation_candidate,18543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18525,curation_candidate,18584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18526,curation_candidate,18614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18527,curation_candidate,18654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18528,curation_candidate,18696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18529,curation_candidate,18730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
18530,curation_candidate,18742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18531,curation_candidate,18750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18532,curation_candidate,18784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18533,curation_candidate,18827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18534,curation_candidate,18891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18535,curation_candidate,18915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18536,curation_candidate,18917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18537,curation_candidate,18942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18538,curation_candidate,18967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18539,curation_candidate,19013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18540,curation_candidate,19048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18541,curation_candidate,19065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18542,curation_candidate,19069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18543,curation_candidate,19133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18544,curation_candidate,19162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18545,curation_candidate,19194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18546,curation_candidate,19196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18547,curation_candidate,19271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18548,curation_candidate,19300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18549,curation_candidate,19392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18550,curation_candidate,19435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18551,curation_candidate,19498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18552,curation_candidate,19506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18553,curation_candidate,19520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18554,curation_candidate,19521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18555,curation_candidate,19529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18556,curation_candidate,19598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18557,curation_candidate,19602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18558,curation_candidate,19773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18559,curation_candidate,19778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18560,curation_candidate,19808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18561,curation_candidate,19831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18562,curation_candidate,19905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18563,curation_candidate,19954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18564,curation_candidate,19995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18565,curation_candidate,20024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18566,curation_candidate,20028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18567,curation_candidate,20095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18568,curation_candidate,20099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18569,curation_candidate,20186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18570,curation_candidate,20300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18571,curation_candidate,20336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18572,curation_candidate,20379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18573,curation_candidate,20381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18574,curation_candidate,20459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18575,curation_candidate,20473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18576,curation_candidate,20493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18577,curation_candidate,20550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
18578,curation_candidate,20650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18579,curation_candidate,20683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18580,curation_candidate,20823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18581,curation_candidate,20825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18582,curation_candidate,20888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18583,curation_candidate,20982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18584,curation_candidate,21057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18585,curation_candidate,21113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18586,curation_candidate,21155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18587,curation_candidate,21170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18588,curation_candidate,21253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18589,curation_candidate,21311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18590,curation_candidate,21455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18591,curation_candidate,21457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18592,curation_candidate,21475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18593,curation_candidate,21541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18594,curation_candidate,21546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18595,curation_candidate,21591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18596,curation_candidate,21639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18597,curation_candidate,21642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18598,curation_candidate,21729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18599,curation_candidate,21730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18600,curation_candidate,21765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
18601,curation_candidate,21766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18602,curation_candidate,21801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18603,curation_candidate,21836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18604,curation_candidate,21891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18605,curation_candidate,21893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18606,curation_candidate,21951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18607,curation_candidate,21970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18608,curation_candidate,21991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18609,curation_candidate,22013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18610,curation_candidate,22054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18611,curation_candidate,22081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18612,curation_candidate,22113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18613,curation_candidate,22120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18614,curation_candidate,22177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18615,curation_candidate,22203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18616,curation_candidate,22289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18617,curation_candidate,22363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18618,curation_candidate,22602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18619,curation_candidate,22616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18620,curation_candidate,22630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18621,curation_candidate,22660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18622,curation_candidate,22672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18623,curation_candidate,22705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18624,curation_candidate,22793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18625,curation_candidate,22950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18626,curation_candidate,22957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18627,curation_candidate,22958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18628,curation_candidate,22985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18629,curation_candidate,23063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18630,curation_candidate,23089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18631,curation_candidate,23095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18632,curation_candidate,23188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18633,curation_candidate,23201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18634,curation_candidate,23215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18635,curation_candidate,23240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18636,curation_candidate,23248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18637,curation_candidate,23261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18638,curation_candidate,23271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18639,curation_candidate,23276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18640,curation_candidate,23286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18641,curation_candidate,23303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18642,curation_candidate,23320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18643,curation_candidate,23348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18644,curation_candidate,23529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18645,curation_candidate,23547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18646,curation_candidate,23563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18647,curation_candidate,23578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18648,curation_candidate,23590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18649,curation_candidate,23674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18650,curation_candidate,23760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18651,curation_candidate,23766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18652,curation_candidate,23820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18653,curation_candidate,23842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18654,curation_candidate,23905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18655,curation_candidate,23908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18656,curation_candidate,23950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18657,curation_candidate,24006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18658,curation_candidate,24058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18659,curation_candidate,24074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18660,curation_candidate,24116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18661,curation_candidate,24196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18662,curation_candidate,24222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18663,curation_candidate,24224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18664,curation_candidate,24306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18665,curation_candidate,24312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18666,curation_candidate,24317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18667,curation_candidate,24325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18668,curation_candidate,24375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18669,curation_candidate,24387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18670,curation_candidate,24397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18671,curation_candidate,24444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18672,curation_candidate,24458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18673,curation_candidate,24494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18674,curation_candidate,24611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18675,curation_candidate,24706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18676,curation_candidate,24742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18677,curation_candidate,24743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18678,curation_candidate,24754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18679,curation_candidate,24876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18680,curation_candidate,24884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18681,curation_candidate,24907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18682,curation_candidate,24970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18683,curation_candidate,24993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18684,curation_candidate,25020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18685,curation_candidate,25043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18686,curation_candidate,25056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18687,curation_candidate,25085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18688,curation_candidate,25088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18689,curation_candidate,25096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18690,curation_candidate,25106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18691,curation_candidate,25152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18692,curation_candidate,25266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18693,curation_candidate,25375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18694,curation_candidate,25385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18695,curation_candidate,25524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18696,curation_candidate,25571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18697,curation_candidate,25613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18698,curation_candidate,25661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18699,curation_candidate,25721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18700,curation_candidate,25757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18701,curation_candidate,25758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18702,curation_candidate,25805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18703,curation_candidate,25817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18704,curation_candidate,25828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18705,curation_candidate,25884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18706,curation_candidate,25887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18707,curation_candidate,25899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18708,curation_candidate,25928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18709,curation_candidate,25965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18710,curation_candidate,26012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18711,curation_candidate,26031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18712,curation_candidate,26032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18713,curation_candidate,26089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18714,curation_candidate,26155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18715,curation_candidate,26194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18716,curation_candidate,26253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18717,curation_candidate,26269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18718,curation_candidate,26272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18719,curation_candidate,26378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18720,curation_candidate,26392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18721,curation_candidate,26400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
18722,curation_candidate,26476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18723,curation_candidate,26479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18724,curation_candidate,26604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18725,curation_candidate,26609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18726,curation_candidate,26620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18727,curation_candidate,26639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18728,curation_candidate,26670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
18729,curation_candidate,26680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18730,curation_candidate,26732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18731,curation_candidate,26737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18732,curation_candidate,26802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18733,curation_candidate,26810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18734,curation_candidate,26847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18735,curation_candidate,26873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18736,curation_candidate,26930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18737,curation_candidate,26970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18738,curation_candidate,26995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18739,curation_candidate,27007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18740,curation_candidate,27029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18741,curation_candidate,27052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18742,curation_candidate,27090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18743,curation_candidate,27117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18744,curation_candidate,27118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18745,curation_candidate,27174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18746,curation_candidate,27199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18747,curation_candidate,27260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18748,curation_candidate,27272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18749,curation_candidate,27305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18750,curation_candidate,27350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18751,curation_candidate,27359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18752,curation_candidate,27388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18753,curation_candidate,27490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18754,curation_candidate,27493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18755,curation_candidate,27494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18756,curation_candidate,27516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18757,curation_candidate,27526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18758,curation_candidate,27566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18759,curation_candidate,27584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18760,curation_candidate,27622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18761,curation_candidate,27631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18762,curation_candidate,27669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18763,curation_candidate,27703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18764,curation_candidate,27704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18765,curation_candidate,27755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18766,curation_candidate,27802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18767,curation_candidate,27820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18768,curation_candidate,27846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18769,curation_candidate,27864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18770,curation_candidate,27870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18771,curation_candidate,27893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18772,curation_candidate,27912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18773,curation_candidate,27916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18774,curation_candidate,27926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18775,curation_candidate,27928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18776,curation_candidate,27947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18777,curation_candidate,27949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18778,curation_candidate,27963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18779,curation_candidate,27992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18780,curation_candidate,27994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18781,curation_candidate,28016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18782,curation_candidate,28030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18783,curation_candidate,28078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18784,curation_candidate,28107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18785,curation_candidate,28112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18786,curation_candidate,28113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18787,curation_candidate,28131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18788,curation_candidate,28173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18789,curation_candidate,28184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18790,curation_candidate,28251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18791,curation_candidate,28259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18792,curation_candidate,28261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18793,curation_candidate,28283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18794,curation_candidate,28358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18795,curation_candidate,28367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18796,curation_candidate,28486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18797,curation_candidate,28512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18798,curation_candidate,28597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18799,curation_candidate,28619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18800,curation_candidate,28671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18801,curation_candidate,28756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18802,curation_candidate,28932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18803,curation_candidate,28949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18804,curation_candidate,29018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18805,curation_candidate,29153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18806,curation_candidate,29185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18807,curation_candidate,29333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
18808,curation_candidate,29371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18809,curation_candidate,29376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18810,curation_candidate,29418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18811,curation_candidate,29534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18812,curation_candidate,29565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18813,curation_candidate,29626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18814,curation_candidate,29656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18815,curation_candidate,29697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18816,curation_candidate,29737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18817,curation_candidate,29889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18818,curation_candidate,29939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18819,curation_candidate,30183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18820,curation_candidate,30241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18821,curation_candidate,30960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18822,curation_candidate,31039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18823,curation_candidate,31123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18824,curation_candidate,31367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
18825,curation_candidate,31468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18826,curation_candidate,31505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18827,curation_candidate,31723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18828,curation_candidate,31772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18829,curation_candidate,31785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18830,curation_candidate,31794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18831,curation_candidate,31817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18832,curation_candidate,31833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18833,curation_candidate,31954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18834,curation_candidate,32129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18835,curation_candidate,32218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18836,curation_candidate,32315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18837,curation_candidate,32488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18838,curation_candidate,32554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18839,curation_candidate,32633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18840,curation_candidate,32720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18841,curation_candidate,32778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18842,curation_candidate,32831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18843,curation_candidate,32978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18844,curation_candidate,33166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18845,curation_candidate,33203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18846,curation_candidate,33248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18847,curation_candidate,33308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18848,curation_candidate,33381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18849,curation_candidate,33477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18850,curation_candidate,33518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18851,curation_candidate,33671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18852,curation_candidate,33700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18853,curation_candidate,33716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18854,curation_candidate,33740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18855,curation_candidate,33908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18856,curation_candidate,33994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18857,curation_candidate,34061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18858,curation_candidate,34070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18859,curation_candidate,34210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18860,curation_candidate,34444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18861,curation_candidate,34489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18862,curation_candidate,34516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18863,curation_candidate,34568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18864,curation_candidate,34877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18865,curation_candidate,34952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18866,curation_candidate,35028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18867,curation_candidate,35058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18868,curation_candidate,35091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18869,curation_candidate,35129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18870,curation_candidate,35198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18871,curation_candidate,35216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18872,curation_candidate,35332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18873,curation_candidate,35386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18874,curation_candidate,35500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18875,curation_candidate,35548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18876,curation_candidate,35598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18877,curation_candidate,35658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18878,curation_candidate,35684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18879,curation_candidate,35725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18880,curation_candidate,35740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18881,curation_candidate,35759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18882,curation_candidate,35822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18883,curation_candidate,35867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18884,curation_candidate,35874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18885,curation_candidate,35933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18886,curation_candidate,35953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18887,curation_candidate,35972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18888,curation_candidate,35979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18889,curation_candidate,36084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18890,curation_candidate,36085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18891,curation_candidate,36114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
18892,curation_candidate,36152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18893,curation_candidate,36163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18894,curation_candidate,36196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18895,curation_candidate,36239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18896,curation_candidate,36284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18897,curation_candidate,36285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18898,curation_candidate,36405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18899,curation_candidate,36431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18900,curation_candidate,36467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18901,curation_candidate,36511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18902,curation_candidate,36680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18903,curation_candidate,36697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18904,curation_candidate,36783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18905,curation_candidate,36802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18906,curation_candidate,36824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18907,curation_candidate,36826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18908,curation_candidate,36859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18909,curation_candidate,36965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18910,curation_candidate,36987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18911,curation_candidate,37019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18912,curation_candidate,37059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18913,curation_candidate,37070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18914,curation_candidate,37112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18915,curation_candidate,37156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18916,curation_candidate,37162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18917,curation_candidate,37173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18918,curation_candidate,37247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18919,curation_candidate,37254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18920,curation_candidate,37320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18921,curation_candidate,37369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18922,curation_candidate,37514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18923,curation_candidate,37586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18924,curation_candidate,37614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18925,curation_candidate,37750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18926,curation_candidate,37782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18927,curation_candidate,37959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18928,curation_candidate,37980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18929,curation_candidate,37992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18930,curation_candidate,38017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18931,curation_candidate,38053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18932,curation_candidate,38162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18933,curation_candidate,38217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18934,curation_candidate,38218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18935,curation_candidate,38307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18936,curation_candidate,16470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18937,curation_candidate,16567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18938,curation_candidate,16579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18939,curation_candidate,16580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18940,curation_candidate,16688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18941,curation_candidate,16708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18942,curation_candidate,16809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18943,curation_candidate,16850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18944,curation_candidate,16852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18945,curation_candidate,16897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18946,curation_candidate,16901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18947,curation_candidate,16914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18948,curation_candidate,16920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18949,curation_candidate,16969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18950,curation_candidate,17014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18951,curation_candidate,17027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18952,curation_candidate,17040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18953,curation_candidate,17043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
18954,curation_candidate,17125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18955,curation_candidate,17133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18956,curation_candidate,17173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18957,curation_candidate,17212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18958,curation_candidate,17240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18959,curation_candidate,17289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18960,curation_candidate,17294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18961,curation_candidate,17303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18962,curation_candidate,17317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18963,curation_candidate,17321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18964,curation_candidate,17339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18965,curation_candidate,17400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18966,curation_candidate,17407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18967,curation_candidate,17412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18968,curation_candidate,17462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18969,curation_candidate,17508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18970,curation_candidate,17522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18971,curation_candidate,17530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18972,curation_candidate,17538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18973,curation_candidate,17554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18974,curation_candidate,17572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18975,curation_candidate,17579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18976,curation_candidate,17624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18977,curation_candidate,17648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18978,curation_candidate,17654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18979,curation_candidate,17792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
18980,curation_candidate,17810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18981,curation_candidate,17830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18982,curation_candidate,17897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18983,curation_candidate,17934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18984,curation_candidate,17992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
18985,curation_candidate,18001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18986,curation_candidate,18039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18987,curation_candidate,18063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18988,curation_candidate,18079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18989,curation_candidate,18175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18990,curation_candidate,18197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18991,curation_candidate,18243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18992,curation_candidate,18322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
18993,curation_candidate,18434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18994,curation_candidate,18469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18995,curation_candidate,18495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
18996,curation_candidate,18528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18997,curation_candidate,18605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18998,curation_candidate,18639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
18999,curation_candidate,18644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19000,curation_candidate,18708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19001,curation_candidate,18725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19002,curation_candidate,18734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19003,curation_candidate,18745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19004,curation_candidate,18746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19005,curation_candidate,18938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19006,curation_candidate,18971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19007,curation_candidate,18997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19008,curation_candidate,19002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19009,curation_candidate,19038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19010,curation_candidate,19055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19011,curation_candidate,19070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19012,curation_candidate,19082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19013,curation_candidate,19091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19014,curation_candidate,19136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19015,curation_candidate,19172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19016,curation_candidate,19333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19017,curation_candidate,19345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19018,curation_candidate,19366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19019,curation_candidate,19419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19020,curation_candidate,19447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19021,curation_candidate,19451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19022,curation_candidate,19474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19023,curation_candidate,19482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19024,curation_candidate,19522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19025,curation_candidate,19571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19026,curation_candidate,19599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19027,curation_candidate,19618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19028,curation_candidate,19679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19029,curation_candidate,19692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19030,curation_candidate,19698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19031,curation_candidate,19707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19032,curation_candidate,19709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19033,curation_candidate,19727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19034,curation_candidate,19777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19035,curation_candidate,19811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19036,curation_candidate,19858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19037,curation_candidate,19865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19038,curation_candidate,19883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19039,curation_candidate,19938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19040,curation_candidate,19952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19041,curation_candidate,19958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19042,curation_candidate,20051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19043,curation_candidate,20124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19044,curation_candidate,20163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19045,curation_candidate,20175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19046,curation_candidate,20191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19047,curation_candidate,20214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19048,curation_candidate,20222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19049,curation_candidate,20246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19050,curation_candidate,20276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19051,curation_candidate,20321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19052,curation_candidate,20352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19053,curation_candidate,20377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19054,curation_candidate,20401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19055,curation_candidate,20419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19056,curation_candidate,20423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19057,curation_candidate,20487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19058,curation_candidate,20554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19059,curation_candidate,20579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19060,curation_candidate,20606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19061,curation_candidate,20758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19062,curation_candidate,20760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19063,curation_candidate,20776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19064,curation_candidate,20911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19065,curation_candidate,20926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19066,curation_candidate,20956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19067,curation_candidate,20992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19068,curation_candidate,21004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19069,curation_candidate,21021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19070,curation_candidate,21023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19071,curation_candidate,21042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19072,curation_candidate,21093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19073,curation_candidate,21115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19074,curation_candidate,21225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19075,curation_candidate,21248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19076,curation_candidate,21325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19077,curation_candidate,21381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19078,curation_candidate,21404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19079,curation_candidate,21419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19080,curation_candidate,21507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19081,curation_candidate,21511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19082,curation_candidate,21524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19083,curation_candidate,21539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19084,curation_candidate,21587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19085,curation_candidate,21758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19086,curation_candidate,21820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19087,curation_candidate,21873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19088,curation_candidate,21886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19089,curation_candidate,21900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19090,curation_candidate,21936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19091,curation_candidate,21958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19092,curation_candidate,22010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19093,curation_candidate,22058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19094,curation_candidate,22064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19095,curation_candidate,22094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19096,curation_candidate,22144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19097,curation_candidate,22253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19098,curation_candidate,22256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19099,curation_candidate,22274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19100,curation_candidate,22346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19101,curation_candidate,22405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19102,curation_candidate,22425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19103,curation_candidate,22444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19104,curation_candidate,22456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19105,curation_candidate,22472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19106,curation_candidate,22485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19107,curation_candidate,22528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19108,curation_candidate,22618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19109,curation_candidate,22627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19110,curation_candidate,22650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19111,curation_candidate,22695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19112,curation_candidate,22725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19113,curation_candidate,22742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19114,curation_candidate,22761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19115,curation_candidate,22762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19116,curation_candidate,22844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19117,curation_candidate,22866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19118,curation_candidate,22884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19119,curation_candidate,22886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19120,curation_candidate,22889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19121,curation_candidate,23009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19122,curation_candidate,23031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19123,curation_candidate,23038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19124,curation_candidate,23051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19125,curation_candidate,23054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19126,curation_candidate,23121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19127,curation_candidate,23214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19128,curation_candidate,23220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19129,curation_candidate,23225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19130,curation_candidate,23287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19131,curation_candidate,23336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19132,curation_candidate,23384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19133,curation_candidate,23404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19134,curation_candidate,23417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19135,curation_candidate,23419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19136,curation_candidate,23454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19137,curation_candidate,23475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19138,curation_candidate,23549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19139,curation_candidate,23637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19140,curation_candidate,23647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19141,curation_candidate,23681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19142,curation_candidate,23709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19143,curation_candidate,23724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19144,curation_candidate,23754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19145,curation_candidate,23763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19146,curation_candidate,23794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19147,curation_candidate,23827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19148,curation_candidate,23830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19149,curation_candidate,23855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19150,curation_candidate,23856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19151,curation_candidate,23866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19152,curation_candidate,23970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19153,curation_candidate,23986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19154,curation_candidate,24033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19155,curation_candidate,24072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19156,curation_candidate,24157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19157,curation_candidate,24174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19158,curation_candidate,24187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19159,curation_candidate,24263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19160,curation_candidate,24279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19161,curation_candidate,24322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19162,curation_candidate,24347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19163,curation_candidate,24384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19164,curation_candidate,24503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19165,curation_candidate,24579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19166,curation_candidate,24702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19167,curation_candidate,24806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19168,curation_candidate,24854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19169,curation_candidate,24895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19170,curation_candidate,24914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19171,curation_candidate,24979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19172,curation_candidate,24995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19173,curation_candidate,24999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19174,curation_candidate,25047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19175,curation_candidate,25103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19176,curation_candidate,25121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19177,curation_candidate,25134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19178,curation_candidate,25184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19179,curation_candidate,25221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19180,curation_candidate,25240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19181,curation_candidate,25392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19182,curation_candidate,25398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19183,curation_candidate,25436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19184,curation_candidate,25440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19185,curation_candidate,25443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19186,curation_candidate,25483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19187,curation_candidate,25584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19188,curation_candidate,25625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19189,curation_candidate,25659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19190,curation_candidate,25808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19191,curation_candidate,25811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19192,curation_candidate,25812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19193,curation_candidate,25821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
19194,curation_candidate,25843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19195,curation_candidate,25846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19196,curation_candidate,25896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19197,curation_candidate,25920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19198,curation_candidate,25984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19199,curation_candidate,26027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
19200,curation_candidate,26130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19201,curation_candidate,26184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19202,curation_candidate,26243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19203,curation_candidate,26277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19204,curation_candidate,26283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19205,curation_candidate,26521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19206,curation_candidate,26565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19207,curation_candidate,26583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19208,curation_candidate,26636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19209,curation_candidate,26654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19210,curation_candidate,26733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19211,curation_candidate,26798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19212,curation_candidate,26864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19213,curation_candidate,26898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19214,curation_candidate,27014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19215,curation_candidate,27045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19216,curation_candidate,27105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19217,curation_candidate,27160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19218,curation_candidate,27166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19219,curation_candidate,27230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19220,curation_candidate,27380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19221,curation_candidate,27381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19222,curation_candidate,27389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19223,curation_candidate,27412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19224,curation_candidate,27422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19225,curation_candidate,27509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19226,curation_candidate,27589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19227,curation_candidate,27640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19228,curation_candidate,27664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19229,curation_candidate,27729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19230,curation_candidate,27749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19231,curation_candidate,27772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19232,curation_candidate,27799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19233,curation_candidate,27826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19234,curation_candidate,27837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19235,curation_candidate,27883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19236,curation_candidate,27902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19237,curation_candidate,27908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19238,curation_candidate,27922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19239,curation_candidate,27944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19240,curation_candidate,27970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19241,curation_candidate,28003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19242,curation_candidate,28008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19243,curation_candidate,28010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19244,curation_candidate,28050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19245,curation_candidate,28068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19246,curation_candidate,28088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19247,curation_candidate,28147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19248,curation_candidate,28179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19249,curation_candidate,28255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19250,curation_candidate,28265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19251,curation_candidate,28271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19252,curation_candidate,28295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19253,curation_candidate,28296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19254,curation_candidate,28339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19255,curation_candidate,28400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19256,curation_candidate,28443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
19257,curation_candidate,28446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19258,curation_candidate,28487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19259,curation_candidate,28522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19260,curation_candidate,28536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19261,curation_candidate,28557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19262,curation_candidate,28567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19263,curation_candidate,28649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19264,curation_candidate,28721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19265,curation_candidate,28760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19266,curation_candidate,28767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19267,curation_candidate,28854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19268,curation_candidate,28899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19269,curation_candidate,28900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19270,curation_candidate,28969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19271,curation_candidate,29009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19272,curation_candidate,29030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19273,curation_candidate,29118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19274,curation_candidate,29152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19275,curation_candidate,29174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19276,curation_candidate,29190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19277,curation_candidate,29273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19278,curation_candidate,29300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19279,curation_candidate,29319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19280,curation_candidate,29382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19281,curation_candidate,29420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19282,curation_candidate,29473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19283,curation_candidate,29474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19284,curation_candidate,29548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19285,curation_candidate,29607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19286,curation_candidate,29730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19287,curation_candidate,29762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19288,curation_candidate,29992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19289,curation_candidate,30041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19290,curation_candidate,30133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
19291,curation_candidate,30329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19292,curation_candidate,30510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19293,curation_candidate,30576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19294,curation_candidate,30597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19295,curation_candidate,30600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19296,curation_candidate,30812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19297,curation_candidate,30898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19298,curation_candidate,30931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19299,curation_candidate,30994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19300,curation_candidate,31001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19301,curation_candidate,31077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19302,curation_candidate,31166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19303,curation_candidate,31428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19304,curation_candidate,31545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19305,curation_candidate,31717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19306,curation_candidate,31766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19307,curation_candidate,31826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19308,curation_candidate,31866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19309,curation_candidate,32031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19310,curation_candidate,32124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19311,curation_candidate,32196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19312,curation_candidate,32288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19313,curation_candidate,32390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19314,curation_candidate,32411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
19315,curation_candidate,32667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19316,curation_candidate,32887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19317,curation_candidate,32895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19318,curation_candidate,32975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19319,curation_candidate,32977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19320,curation_candidate,33018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19321,curation_candidate,33101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19322,curation_candidate,33105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19323,curation_candidate,33226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19324,curation_candidate,33307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19325,curation_candidate,33322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19326,curation_candidate,33382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
19327,curation_candidate,33431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19328,curation_candidate,33503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19329,curation_candidate,33510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19330,curation_candidate,33675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19331,curation_candidate,33681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19332,curation_candidate,33753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19333,curation_candidate,33850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19334,curation_candidate,33864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19335,curation_candidate,33868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19336,curation_candidate,33956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19337,curation_candidate,34093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19338,curation_candidate,34488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19339,curation_candidate,34517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19340,curation_candidate,34535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19341,curation_candidate,34723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19342,curation_candidate,34786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19343,curation_candidate,34884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19344,curation_candidate,34897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19345,curation_candidate,34907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19346,curation_candidate,34926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19347,curation_candidate,35102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19348,curation_candidate,35170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19349,curation_candidate,35199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19350,curation_candidate,35314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19351,curation_candidate,35352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19352,curation_candidate,35409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19353,curation_candidate,35465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19354,curation_candidate,35507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
19355,curation_candidate,35590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19356,curation_candidate,35596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19357,curation_candidate,35709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19358,curation_candidate,35745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19359,curation_candidate,35787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19360,curation_candidate,35824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19361,curation_candidate,36086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19362,curation_candidate,36149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19363,curation_candidate,36156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
19364,curation_candidate,36176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19365,curation_candidate,36206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19366,curation_candidate,36207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19367,curation_candidate,36208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19368,curation_candidate,36246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19369,curation_candidate,36264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19370,curation_candidate,36375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19371,curation_candidate,36376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19372,curation_candidate,36481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19373,curation_candidate,36572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19374,curation_candidate,36596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19375,curation_candidate,36627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19376,curation_candidate,36653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19377,curation_candidate,36668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19378,curation_candidate,36726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19379,curation_candidate,36744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19380,curation_candidate,36763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19381,curation_candidate,36840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19382,curation_candidate,36885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19383,curation_candidate,36938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19384,curation_candidate,37046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19385,curation_candidate,37166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19386,curation_candidate,37232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19387,curation_candidate,37281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19388,curation_candidate,37304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19389,curation_candidate,37404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19390,curation_candidate,37426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19391,curation_candidate,37615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19392,curation_candidate,37854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19393,curation_candidate,37858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19394,curation_candidate,37982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19395,curation_candidate,37989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19396,curation_candidate,38014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19397,curation_candidate,38084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19398,curation_candidate,38104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19399,curation_candidate,38126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19400,curation_candidate,38231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19401,curation_candidate,38253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19402,curation_candidate,38316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19403,curation_candidate,16334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19404,curation_candidate,16357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19405,curation_candidate,16368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19406,curation_candidate,16371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19407,curation_candidate,16519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19408,curation_candidate,16570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19409,curation_candidate,16578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19410,curation_candidate,16808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19411,curation_candidate,16853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19412,curation_candidate,16924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19413,curation_candidate,17183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19414,curation_candidate,17363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19415,curation_candidate,17428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19416,curation_candidate,17450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19417,curation_candidate,17481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19418,curation_candidate,17568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19419,curation_candidate,17571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19420,curation_candidate,17659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19421,curation_candidate,17739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19422,curation_candidate,17768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19423,curation_candidate,17826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19424,curation_candidate,17895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19425,curation_candidate,17915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19426,curation_candidate,17931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19427,curation_candidate,17951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19428,curation_candidate,17975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19429,curation_candidate,18000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19430,curation_candidate,18018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19431,curation_candidate,18085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19432,curation_candidate,18089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19433,curation_candidate,18098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19434,curation_candidate,18125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19435,curation_candidate,18134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19436,curation_candidate,18210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19437,curation_candidate,18239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19438,curation_candidate,18250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
19439,curation_candidate,18260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19440,curation_candidate,18279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19441,curation_candidate,18342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19442,curation_candidate,18515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19443,curation_candidate,18695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19444,curation_candidate,18699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19445,curation_candidate,18727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19446,curation_candidate,18733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19447,curation_candidate,18748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19448,curation_candidate,18753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19449,curation_candidate,18769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19450,curation_candidate,18803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19451,curation_candidate,18855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19452,curation_candidate,18875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19453,curation_candidate,18904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19454,curation_candidate,18934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19455,curation_candidate,18964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19456,curation_candidate,18969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19457,curation_candidate,18995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19458,curation_candidate,19011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19459,curation_candidate,19017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19460,curation_candidate,19035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19461,curation_candidate,19089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19462,curation_candidate,19179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19463,curation_candidate,19249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19464,curation_candidate,19262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19465,curation_candidate,19299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19466,curation_candidate,19307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19467,curation_candidate,19338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19468,curation_candidate,19343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19469,curation_candidate,19365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19470,curation_candidate,19409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19471,curation_candidate,19532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19472,curation_candidate,19616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19473,curation_candidate,19635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19474,curation_candidate,19803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19475,curation_candidate,19810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19476,curation_candidate,19813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19477,curation_candidate,19816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19478,curation_candidate,19823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19479,curation_candidate,19853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19480,curation_candidate,19941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19481,curation_candidate,19965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19482,curation_candidate,19966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19483,curation_candidate,20056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19484,curation_candidate,20087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19485,curation_candidate,20188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19486,curation_candidate,20223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19487,curation_candidate,20323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19488,curation_candidate,20356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19489,curation_candidate,20424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19490,curation_candidate,20503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19491,curation_candidate,20532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19492,curation_candidate,20547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19493,curation_candidate,20552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19494,curation_candidate,20568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19495,curation_candidate,20681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19496,curation_candidate,20783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19497,curation_candidate,20800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19498,curation_candidate,20839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19499,curation_candidate,20842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19500,curation_candidate,20853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
19501,curation_candidate,20868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19502,curation_candidate,20898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19503,curation_candidate,20959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19504,curation_candidate,21027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19505,curation_candidate,21030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19506,curation_candidate,21044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19507,curation_candidate,21107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19508,curation_candidate,21129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19509,curation_candidate,21233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19510,curation_candidate,21247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19511,curation_candidate,21259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19512,curation_candidate,21456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19513,curation_candidate,21659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19514,curation_candidate,21663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19515,curation_candidate,21733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19516,curation_candidate,21760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19517,curation_candidate,21848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19518,curation_candidate,21922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19519,curation_candidate,21930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19520,curation_candidate,21973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19521,curation_candidate,21994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19522,curation_candidate,22031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19523,curation_candidate,22045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19524,curation_candidate,22110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19525,curation_candidate,22117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19526,curation_candidate,22155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19527,curation_candidate,22242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19528,curation_candidate,22438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19529,curation_candidate,22466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19530,curation_candidate,22539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19531,curation_candidate,22604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19532,curation_candidate,22643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19533,curation_candidate,22767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19534,curation_candidate,22830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19535,curation_candidate,22831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19536,curation_candidate,22863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19537,curation_candidate,22933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19538,curation_candidate,22964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19539,curation_candidate,22997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19540,curation_candidate,23049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19541,curation_candidate,23058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19542,curation_candidate,23077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19543,curation_candidate,23100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19544,curation_candidate,23120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19545,curation_candidate,23136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19546,curation_candidate,23152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19547,curation_candidate,23318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19548,curation_candidate,23365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19549,curation_candidate,23366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19550,curation_candidate,23412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19551,curation_candidate,23522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19552,curation_candidate,23528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19553,curation_candidate,23593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19554,curation_candidate,23612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19555,curation_candidate,23616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19556,curation_candidate,23682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19557,curation_candidate,23729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19558,curation_candidate,23786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19559,curation_candidate,23804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19560,curation_candidate,23818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19561,curation_candidate,23836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19562,curation_candidate,23895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19563,curation_candidate,23898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19564,curation_candidate,23957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19565,curation_candidate,23993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19566,curation_candidate,24047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19567,curation_candidate,24084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19568,curation_candidate,24134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19569,curation_candidate,24192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19570,curation_candidate,24195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19571,curation_candidate,24202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19572,curation_candidate,24233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19573,curation_candidate,24249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19574,curation_candidate,24272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19575,curation_candidate,24290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19576,curation_candidate,24291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19577,curation_candidate,24454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19578,curation_candidate,24477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19579,curation_candidate,24484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19580,curation_candidate,24546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19581,curation_candidate,24572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19582,curation_candidate,24592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19583,curation_candidate,24600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19584,curation_candidate,24617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19585,curation_candidate,24626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19586,curation_candidate,24643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19587,curation_candidate,24733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19588,curation_candidate,24795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19589,curation_candidate,25023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19590,curation_candidate,25201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19591,curation_candidate,25271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19592,curation_candidate,25325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19593,curation_candidate,25333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19594,curation_candidate,25424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19595,curation_candidate,25439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19596,curation_candidate,25441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19597,curation_candidate,25492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19598,curation_candidate,25527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19599,curation_candidate,25560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19600,curation_candidate,25653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19601,curation_candidate,25689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19602,curation_candidate,25706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19603,curation_candidate,25708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19604,curation_candidate,25752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19605,curation_candidate,25806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19606,curation_candidate,25911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19607,curation_candidate,25912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19608,curation_candidate,25930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19609,curation_candidate,25976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19610,curation_candidate,26042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19611,curation_candidate,26056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19612,curation_candidate,26116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19613,curation_candidate,26133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19614,curation_candidate,26149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19615,curation_candidate,26164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19616,curation_candidate,26189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19617,curation_candidate,26223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19618,curation_candidate,26232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19619,curation_candidate,26448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19620,curation_candidate,26552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19621,curation_candidate,26682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19622,curation_candidate,26698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19623,curation_candidate,26704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19624,curation_candidate,26720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19625,curation_candidate,26746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19626,curation_candidate,26764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19627,curation_candidate,26771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19628,curation_candidate,26784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19629,curation_candidate,26793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19630,curation_candidate,26811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19631,curation_candidate,26818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19632,curation_candidate,26821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19633,curation_candidate,26893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19634,curation_candidate,26927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19635,curation_candidate,26963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19636,curation_candidate,27010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19637,curation_candidate,27023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19638,curation_candidate,27064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19639,curation_candidate,27078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19640,curation_candidate,27193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19641,curation_candidate,27235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19642,curation_candidate,27237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19643,curation_candidate,27240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19644,curation_candidate,27297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19645,curation_candidate,27302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19646,curation_candidate,27314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19647,curation_candidate,27450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19648,curation_candidate,27480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19649,curation_candidate,27541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19650,curation_candidate,27639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19651,curation_candidate,27683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19652,curation_candidate,27685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19653,curation_candidate,27744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19654,curation_candidate,27747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19655,curation_candidate,27763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19656,curation_candidate,27785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19657,curation_candidate,27787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19658,curation_candidate,27843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19659,curation_candidate,27876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19660,curation_candidate,27877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19661,curation_candidate,27885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19662,curation_candidate,27892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
19663,curation_candidate,27901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19664,curation_candidate,28025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19665,curation_candidate,28102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19666,curation_candidate,28104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19667,curation_candidate,28143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19668,curation_candidate,28157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19669,curation_candidate,28180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19670,curation_candidate,28233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19671,curation_candidate,28312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19672,curation_candidate,28374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19673,curation_candidate,28394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
19674,curation_candidate,28410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19675,curation_candidate,28454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19676,curation_candidate,28471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19677,curation_candidate,28546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19678,curation_candidate,28564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19679,curation_candidate,28618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19680,curation_candidate,28662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19681,curation_candidate,28670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19682,curation_candidate,28747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19683,curation_candidate,28763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19684,curation_candidate,28803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19685,curation_candidate,28809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19686,curation_candidate,28923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19687,curation_candidate,29045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19688,curation_candidate,29067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19689,curation_candidate,29077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19690,curation_candidate,29086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19691,curation_candidate,29141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19692,curation_candidate,29176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19693,curation_candidate,29252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19694,curation_candidate,29328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19695,curation_candidate,29347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19696,curation_candidate,29470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19697,curation_candidate,29493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19698,curation_candidate,29551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19699,curation_candidate,29948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19700,curation_candidate,30059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19701,curation_candidate,30312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19702,curation_candidate,30495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19703,curation_candidate,30524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19704,curation_candidate,30608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19705,curation_candidate,30706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19706,curation_candidate,30724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19707,curation_candidate,30777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19708,curation_candidate,30880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19709,curation_candidate,30895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19710,curation_candidate,31115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19711,curation_candidate,31144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19712,curation_candidate,31200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19713,curation_candidate,31302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19714,curation_candidate,31332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19715,curation_candidate,31354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19716,curation_candidate,31391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19717,curation_candidate,31510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19718,curation_candidate,31568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19719,curation_candidate,31758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19720,curation_candidate,31861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19721,curation_candidate,31940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19722,curation_candidate,32079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19723,curation_candidate,32160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19724,curation_candidate,32198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19725,curation_candidate,32314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19726,curation_candidate,32403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19727,curation_candidate,32470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19728,curation_candidate,32561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19729,curation_candidate,32755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19730,curation_candidate,32756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19731,curation_candidate,32922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19732,curation_candidate,32986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19733,curation_candidate,32994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19734,curation_candidate,32999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19735,curation_candidate,33288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19736,curation_candidate,33372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19737,curation_candidate,33407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19738,curation_candidate,33445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19739,curation_candidate,33523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19740,curation_candidate,33546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19741,curation_candidate,33621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19742,curation_candidate,33689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19743,curation_candidate,33701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19744,curation_candidate,33702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19745,curation_candidate,33741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19746,curation_candidate,33759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19747,curation_candidate,33862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19748,curation_candidate,33925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19749,curation_candidate,33991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19750,curation_candidate,34017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19751,curation_candidate,34171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19752,curation_candidate,34305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19753,curation_candidate,34630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19754,curation_candidate,34706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19755,curation_candidate,34718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19756,curation_candidate,34859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19757,curation_candidate,34906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19758,curation_candidate,34982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19759,curation_candidate,35088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19760,curation_candidate,35105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19761,curation_candidate,35112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19762,curation_candidate,35117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19763,curation_candidate,35494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19764,curation_candidate,35603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19765,curation_candidate,35614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19766,curation_candidate,35763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19767,curation_candidate,35990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19768,curation_candidate,36049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19769,curation_candidate,36059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19770,curation_candidate,36078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19771,curation_candidate,36220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19772,curation_candidate,36259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19773,curation_candidate,36274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19774,curation_candidate,36409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19775,curation_candidate,36429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19776,curation_candidate,36537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19777,curation_candidate,36579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19778,curation_candidate,36891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19779,curation_candidate,36984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19780,curation_candidate,37066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19781,curation_candidate,37587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19782,curation_candidate,37588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19783,curation_candidate,37649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19784,curation_candidate,37752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19785,curation_candidate,37777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19786,curation_candidate,38239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19787,curation_candidate,38258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19788,curation_candidate,38281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19789,curation_candidate,16489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19790,curation_candidate,16501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19791,curation_candidate,16598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19792,curation_candidate,16661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19793,curation_candidate,16719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19794,curation_candidate,16826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19795,curation_candidate,16884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19796,curation_candidate,17002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19797,curation_candidate,17052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19798,curation_candidate,17055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19799,curation_candidate,17115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19800,curation_candidate,17179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19801,curation_candidate,17208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19802,curation_candidate,17225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19803,curation_candidate,17245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19804,curation_candidate,17296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19805,curation_candidate,17382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19806,curation_candidate,17383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19807,curation_candidate,17399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19808,curation_candidate,17485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19809,curation_candidate,17546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19810,curation_candidate,17550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19811,curation_candidate,17560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19812,curation_candidate,17582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19813,curation_candidate,17591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19814,curation_candidate,17798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19815,curation_candidate,17806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19816,curation_candidate,17811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19817,curation_candidate,17873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19818,curation_candidate,18080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19819,curation_candidate,18106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19820,curation_candidate,18129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19821,curation_candidate,18167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19822,curation_candidate,18176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19823,curation_candidate,18218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19824,curation_candidate,18219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19825,curation_candidate,18344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19826,curation_candidate,18347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19827,curation_candidate,18381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19828,curation_candidate,18454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19829,curation_candidate,18664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19830,curation_candidate,18681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19831,curation_candidate,18701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19832,curation_candidate,18703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19833,curation_candidate,18812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19834,curation_candidate,18842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19835,curation_candidate,18861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19836,curation_candidate,18883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19837,curation_candidate,18896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19838,curation_candidate,18928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19839,curation_candidate,18937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19840,curation_candidate,18940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19841,curation_candidate,18947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19842,curation_candidate,18984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19843,curation_candidate,19068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19844,curation_candidate,19132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19845,curation_candidate,19151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19846,curation_candidate,19285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19847,curation_candidate,19350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19848,curation_candidate,19359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19849,curation_candidate,19418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19850,curation_candidate,19427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19851,curation_candidate,19589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19852,curation_candidate,19665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19853,curation_candidate,19717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19854,curation_candidate,19738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19855,curation_candidate,19749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19856,curation_candidate,19750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19857,curation_candidate,19758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19858,curation_candidate,19780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19859,curation_candidate,19820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19860,curation_candidate,19852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19861,curation_candidate,19930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19862,curation_candidate,20054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19863,curation_candidate,20061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19864,curation_candidate,20119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19865,curation_candidate,20292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19866,curation_candidate,20342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19867,curation_candidate,20368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19868,curation_candidate,20371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19869,curation_candidate,20461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19870,curation_candidate,20466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19871,curation_candidate,20570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19872,curation_candidate,20624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19873,curation_candidate,20625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19874,curation_candidate,20673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19875,curation_candidate,20811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19876,curation_candidate,20816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19877,curation_candidate,20951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19878,curation_candidate,20960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19879,curation_candidate,21024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19880,curation_candidate,21035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19881,curation_candidate,21130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19882,curation_candidate,21212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19883,curation_candidate,21231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19884,curation_candidate,21258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19885,curation_candidate,21265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19886,curation_candidate,21342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19887,curation_candidate,21393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19888,curation_candidate,21519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19889,curation_candidate,21560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19890,curation_candidate,21585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19891,curation_candidate,21669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19892,curation_candidate,21738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19893,curation_candidate,21753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19894,curation_candidate,21771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19895,curation_candidate,21800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19896,curation_candidate,21806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19897,curation_candidate,21821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19898,curation_candidate,21846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19899,curation_candidate,21935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19900,curation_candidate,21983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19901,curation_candidate,22115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
19902,curation_candidate,22176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19903,curation_candidate,22195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19904,curation_candidate,22197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19905,curation_candidate,22200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19906,curation_candidate,22228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19907,curation_candidate,22248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19908,curation_candidate,22314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19909,curation_candidate,22396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19910,curation_candidate,22430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19911,curation_candidate,22552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19912,curation_candidate,22583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19913,curation_candidate,22593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19914,curation_candidate,22598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19915,curation_candidate,22614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19916,curation_candidate,22752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19917,curation_candidate,22853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19918,curation_candidate,22946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19919,curation_candidate,23013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19920,curation_candidate,23099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19921,curation_candidate,23118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19922,curation_candidate,23149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19923,curation_candidate,23281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19924,curation_candidate,23302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19925,curation_candidate,23490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19926,curation_candidate,23526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19927,curation_candidate,23530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19928,curation_candidate,23596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19929,curation_candidate,23610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19930,curation_candidate,23641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19931,curation_candidate,23693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19932,curation_candidate,23710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19933,curation_candidate,23809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19934,curation_candidate,23829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19935,curation_candidate,23861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19936,curation_candidate,23864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
19937,curation_candidate,23892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19938,curation_candidate,23955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19939,curation_candidate,23978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19940,curation_candidate,23983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19941,curation_candidate,24018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19942,curation_candidate,24128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19943,curation_candidate,24179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19944,curation_candidate,24252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19945,curation_candidate,24270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19946,curation_candidate,24362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19947,curation_candidate,24382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19948,curation_candidate,24410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19949,curation_candidate,24465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19950,curation_candidate,24587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19951,curation_candidate,24614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19952,curation_candidate,24659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19953,curation_candidate,24712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19954,curation_candidate,24801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19955,curation_candidate,25032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19956,curation_candidate,25044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19957,curation_candidate,25075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19958,curation_candidate,25111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19959,curation_candidate,25174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19960,curation_candidate,25246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
19961,curation_candidate,25328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19962,curation_candidate,25371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19963,curation_candidate,25413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19964,curation_candidate,25417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19965,curation_candidate,25489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19966,curation_candidate,25528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19967,curation_candidate,25538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19968,curation_candidate,25573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19969,curation_candidate,25632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19970,curation_candidate,25707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19971,curation_candidate,25712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19972,curation_candidate,25820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
19973,curation_candidate,25891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19974,curation_candidate,25897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19975,curation_candidate,25931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19976,curation_candidate,25934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19977,curation_candidate,26097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19978,curation_candidate,26098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19979,curation_candidate,26131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19980,curation_candidate,26136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19981,curation_candidate,26150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19982,curation_candidate,26172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19983,curation_candidate,26186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19984,curation_candidate,26275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19985,curation_candidate,26525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19986,curation_candidate,26621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19987,curation_candidate,26633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19988,curation_candidate,26645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19989,curation_candidate,26695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19990,curation_candidate,26750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
19991,curation_candidate,26761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19992,curation_candidate,26765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19993,curation_candidate,26775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19994,curation_candidate,26788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19995,curation_candidate,26804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19996,curation_candidate,26882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
19997,curation_candidate,26920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19998,curation_candidate,26926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
19999,curation_candidate,26968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20000,curation_candidate,26969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20001,curation_candidate,26991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20002,curation_candidate,27042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20003,curation_candidate,27194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20004,curation_candidate,27218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20005,curation_candidate,27273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20006,curation_candidate,27295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20007,curation_candidate,27309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20008,curation_candidate,27409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20009,curation_candidate,27470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20010,curation_candidate,27515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20011,curation_candidate,27533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20012,curation_candidate,27547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20013,curation_candidate,27624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20014,curation_candidate,27721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20015,curation_candidate,27767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20016,curation_candidate,27771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20017,curation_candidate,27807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20018,curation_candidate,27850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20019,curation_candidate,27869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20020,curation_candidate,27878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20021,curation_candidate,27887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20022,curation_candidate,27942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20023,curation_candidate,27977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20024,curation_candidate,28071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20025,curation_candidate,28153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20026,curation_candidate,28223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20027,curation_candidate,28302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20028,curation_candidate,28308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20029,curation_candidate,28369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20030,curation_candidate,28472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20031,curation_candidate,28493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
20032,curation_candidate,28514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20033,curation_candidate,28560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20034,curation_candidate,28762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20035,curation_candidate,28817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20036,curation_candidate,28844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20037,curation_candidate,28903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20038,curation_candidate,28956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20039,curation_candidate,28987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20040,curation_candidate,28995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20041,curation_candidate,29044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20042,curation_candidate,29116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20043,curation_candidate,29164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20044,curation_candidate,29555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20045,curation_candidate,29640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20046,curation_candidate,29885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20047,curation_candidate,29983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20048,curation_candidate,30089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20049,curation_candidate,30250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20050,curation_candidate,30261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20051,curation_candidate,30345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20052,curation_candidate,30451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20053,curation_candidate,30714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20054,curation_candidate,30822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20055,curation_candidate,30914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20056,curation_candidate,30941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20057,curation_candidate,30950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20058,curation_candidate,30982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20059,curation_candidate,31041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20060,curation_candidate,31119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20061,curation_candidate,31145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20062,curation_candidate,31208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20063,curation_candidate,31224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20064,curation_candidate,31262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20065,curation_candidate,31291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20066,curation_candidate,31294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20067,curation_candidate,31350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20068,curation_candidate,31677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20069,curation_candidate,31925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20070,curation_candidate,31965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20071,curation_candidate,32057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20072,curation_candidate,32145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20073,curation_candidate,32258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20074,curation_candidate,32412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20075,curation_candidate,32455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20076,curation_candidate,32472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20077,curation_candidate,32542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20078,curation_candidate,32577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20079,curation_candidate,32586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20080,curation_candidate,32615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20081,curation_candidate,32683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20082,curation_candidate,32700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20083,curation_candidate,32717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20084,curation_candidate,32728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20085,curation_candidate,32738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20086,curation_candidate,32788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20087,curation_candidate,33008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20088,curation_candidate,33111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20089,curation_candidate,33152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20090,curation_candidate,33210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20091,curation_candidate,33256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20092,curation_candidate,33358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20093,curation_candidate,33359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20094,curation_candidate,33404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20095,curation_candidate,33439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20096,curation_candidate,33703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20097,curation_candidate,33713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20098,curation_candidate,33738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20099,curation_candidate,33739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20100,curation_candidate,33742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20101,curation_candidate,33793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20102,curation_candidate,33822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20103,curation_candidate,33951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20104,curation_candidate,34462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20105,curation_candidate,34585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20106,curation_candidate,34622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20107,curation_candidate,34645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20108,curation_candidate,34936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20109,curation_candidate,34957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20110,curation_candidate,35003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20111,curation_candidate,35087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20112,curation_candidate,35359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20113,curation_candidate,35366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20114,curation_candidate,35499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20115,curation_candidate,35502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20116,curation_candidate,35510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20117,curation_candidate,35516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20118,curation_candidate,35582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20119,curation_candidate,35615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20120,curation_candidate,35616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20121,curation_candidate,35736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20122,curation_candidate,35799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20123,curation_candidate,35851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20124,curation_candidate,35947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20125,curation_candidate,36453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20126,curation_candidate,36731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20127,curation_candidate,36733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20128,curation_candidate,37090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20129,curation_candidate,37092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20130,curation_candidate,37589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20131,curation_candidate,37683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20132,curation_candidate,37859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20133,curation_candidate,37993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20134,curation_candidate,38163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20135,curation_candidate,38220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20136,curation_candidate,38283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20137,curation_candidate,16362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20138,curation_candidate,16427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20139,curation_candidate,16461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20140,curation_candidate,16476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20141,curation_candidate,16609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20142,curation_candidate,16616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20143,curation_candidate,16716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20144,curation_candidate,16778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20145,curation_candidate,16861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20146,curation_candidate,16988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20147,curation_candidate,17076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20148,curation_candidate,17270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20149,curation_candidate,17327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20150,curation_candidate,17439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20151,curation_candidate,17461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20152,curation_candidate,17483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20153,curation_candidate,17487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20154,curation_candidate,17490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20155,curation_candidate,17497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20156,curation_candidate,17625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20157,curation_candidate,17651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20158,curation_candidate,17681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20159,curation_candidate,17705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20160,curation_candidate,17746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20161,curation_candidate,17770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20162,curation_candidate,17872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20163,curation_candidate,18040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20164,curation_candidate,18075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20165,curation_candidate,18158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20166,curation_candidate,18326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20167,curation_candidate,18450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20168,curation_candidate,18513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20169,curation_candidate,18562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20170,curation_candidate,18578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20171,curation_candidate,18801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20172,curation_candidate,18885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20173,curation_candidate,18925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20174,curation_candidate,19054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20175,curation_candidate,19077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20176,curation_candidate,19273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20177,curation_candidate,19330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20178,curation_candidate,19339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20179,curation_candidate,19388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20180,curation_candidate,19481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20181,curation_candidate,19559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20182,curation_candidate,19574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20183,curation_candidate,19615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20184,curation_candidate,19658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20185,curation_candidate,19675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20186,curation_candidate,19767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20187,curation_candidate,19791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20188,curation_candidate,19839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20189,curation_candidate,19903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20190,curation_candidate,19964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20191,curation_candidate,19985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20192,curation_candidate,19988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20193,curation_candidate,20072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20194,curation_candidate,20114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20195,curation_candidate,20181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20196,curation_candidate,20206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20197,curation_candidate,20280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20198,curation_candidate,20287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20199,curation_candidate,20382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20200,curation_candidate,20409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20201,curation_candidate,20475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20202,curation_candidate,20680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20203,curation_candidate,20750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20204,curation_candidate,20935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20205,curation_candidate,20938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20206,curation_candidate,20999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20207,curation_candidate,21074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20208,curation_candidate,21077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20209,curation_candidate,21078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20210,curation_candidate,21111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20211,curation_candidate,21153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20212,curation_candidate,21272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20213,curation_candidate,21274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20214,curation_candidate,21316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20215,curation_candidate,21423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20216,curation_candidate,21432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20217,curation_candidate,21438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20218,curation_candidate,21492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20219,curation_candidate,21665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20220,curation_candidate,21697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20221,curation_candidate,21847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20222,curation_candidate,21876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20223,curation_candidate,22076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20224,curation_candidate,22174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20225,curation_candidate,22216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20226,curation_candidate,22233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20227,curation_candidate,22377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20228,curation_candidate,22449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20229,curation_candidate,22465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20230,curation_candidate,22482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20231,curation_candidate,22590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20232,curation_candidate,22617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20233,curation_candidate,22751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20234,curation_candidate,22773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20235,curation_candidate,22895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20236,curation_candidate,22983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20237,curation_candidate,23349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20238,curation_candidate,23354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20239,curation_candidate,23368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20240,curation_candidate,23418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20241,curation_candidate,23655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20242,curation_candidate,23675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20243,curation_candidate,23851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20244,curation_candidate,23889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20245,curation_candidate,24175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20246,curation_candidate,24206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20247,curation_candidate,24262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20248,curation_candidate,24267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20249,curation_candidate,24271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20250,curation_candidate,24369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20251,curation_candidate,24373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20252,curation_candidate,24535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20253,curation_candidate,24673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20254,curation_candidate,24693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20255,curation_candidate,24773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
20256,curation_candidate,24842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20257,curation_candidate,24857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20258,curation_candidate,24926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20259,curation_candidate,24933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20260,curation_candidate,24968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20261,curation_candidate,25018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20262,curation_candidate,25101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20263,curation_candidate,25236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20264,curation_candidate,25422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20265,curation_candidate,25559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20266,curation_candidate,25588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20267,curation_candidate,25617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20268,curation_candidate,25668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20269,curation_candidate,25687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20270,curation_candidate,25717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20271,curation_candidate,25736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20272,curation_candidate,25738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20273,curation_candidate,25829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
20274,curation_candidate,25853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20275,curation_candidate,25904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20276,curation_candidate,25948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20277,curation_candidate,26000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20278,curation_candidate,26202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20279,curation_candidate,26251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20280,curation_candidate,26341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20281,curation_candidate,26407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20282,curation_candidate,26597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20283,curation_candidate,26685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20284,curation_candidate,26705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20285,curation_candidate,26721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20286,curation_candidate,26850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20287,curation_candidate,26869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20288,curation_candidate,26909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20289,curation_candidate,27012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20290,curation_candidate,27076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20291,curation_candidate,27101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20292,curation_candidate,27130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20293,curation_candidate,27209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20294,curation_candidate,27345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20295,curation_candidate,27399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20296,curation_candidate,27403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20297,curation_candidate,27498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20298,curation_candidate,27607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20299,curation_candidate,27681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20300,curation_candidate,27726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20301,curation_candidate,27734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20302,curation_candidate,27914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20303,curation_candidate,28013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20304,curation_candidate,28042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20305,curation_candidate,28067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20306,curation_candidate,28077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20307,curation_candidate,28218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20308,curation_candidate,28412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20309,curation_candidate,28453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20310,curation_candidate,28507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20311,curation_candidate,28533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20312,curation_candidate,28629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20313,curation_candidate,28964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20314,curation_candidate,29051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20315,curation_candidate,29128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20316,curation_candidate,29142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20317,curation_candidate,29193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20318,curation_candidate,29222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20319,curation_candidate,29230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20320,curation_candidate,29238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20321,curation_candidate,29312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20322,curation_candidate,29357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20323,curation_candidate,29361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20324,curation_candidate,29462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20325,curation_candidate,29991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20326,curation_candidate,30068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20327,curation_candidate,30134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20328,curation_candidate,30155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20329,curation_candidate,30169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20330,curation_candidate,30212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20331,curation_candidate,30214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20332,curation_candidate,30236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20333,curation_candidate,30448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20334,curation_candidate,30508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20335,curation_candidate,30545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20336,curation_candidate,30643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20337,curation_candidate,30653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20338,curation_candidate,30731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20339,curation_candidate,30743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20340,curation_candidate,30987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20341,curation_candidate,31120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20342,curation_candidate,31229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20343,curation_candidate,31375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20344,curation_candidate,31448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20345,curation_candidate,31553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20346,curation_candidate,31584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20347,curation_candidate,31631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20348,curation_candidate,31688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20349,curation_candidate,31735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20350,curation_candidate,31789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20351,curation_candidate,31848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20352,curation_candidate,31979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20353,curation_candidate,31991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20354,curation_candidate,32021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20355,curation_candidate,32054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20356,curation_candidate,32104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20357,curation_candidate,32135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20358,curation_candidate,32173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20359,curation_candidate,32183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20360,curation_candidate,32372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20361,curation_candidate,32434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20362,curation_candidate,32444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20363,curation_candidate,32549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20364,curation_candidate,32575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20365,curation_candidate,32594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20366,curation_candidate,32622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20367,curation_candidate,32673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20368,curation_candidate,32757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20369,curation_candidate,32784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20370,curation_candidate,32818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20371,curation_candidate,32889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20372,curation_candidate,33054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20373,curation_candidate,33057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20374,curation_candidate,33154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20375,curation_candidate,33206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20376,curation_candidate,33239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20377,curation_candidate,33297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20378,curation_candidate,33443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20379,curation_candidate,33458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20380,curation_candidate,33492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20381,curation_candidate,33594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20382,curation_candidate,33622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20383,curation_candidate,33630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20384,curation_candidate,33800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20385,curation_candidate,33941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20386,curation_candidate,34156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20387,curation_candidate,34605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20388,curation_candidate,34749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20389,curation_candidate,34753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20390,curation_candidate,34780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20391,curation_candidate,34941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20392,curation_candidate,34977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20393,curation_candidate,35118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20394,curation_candidate,35261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20395,curation_candidate,35405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20396,curation_candidate,35436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20397,curation_candidate,35454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20398,curation_candidate,35473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20399,curation_candidate,35511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20400,curation_candidate,35512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20401,curation_candidate,35517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20402,curation_candidate,35518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20403,curation_candidate,35688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20404,curation_candidate,35789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20405,curation_candidate,35790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20406,curation_candidate,36115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20407,curation_candidate,36198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20408,curation_candidate,36232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20409,curation_candidate,36260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20410,curation_candidate,36369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20411,curation_candidate,36370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20412,curation_candidate,36506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20413,curation_candidate,36734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20414,curation_candidate,36816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20415,curation_candidate,36825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
20416,curation_candidate,37017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20417,curation_candidate,37388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20418,curation_candidate,37552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20419,curation_candidate,38128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20420,curation_candidate,38143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20421,curation_candidate,38301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20422,curation_candidate,38319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20423,curation_candidate,16342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20424,curation_candidate,16467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20425,curation_candidate,16513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20426,curation_candidate,16544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20427,curation_candidate,16631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20428,curation_candidate,16667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20429,curation_candidate,17024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20430,curation_candidate,17069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20431,curation_candidate,17352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20432,curation_candidate,17359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20433,curation_candidate,17437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20434,curation_candidate,17613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20435,curation_candidate,17718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20436,curation_candidate,17757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20437,curation_candidate,17765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20438,curation_candidate,17894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20439,curation_candidate,18019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20440,curation_candidate,18173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20441,curation_candidate,18174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20442,curation_candidate,18179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20443,curation_candidate,18359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20444,curation_candidate,18494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20445,curation_candidate,18603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20446,curation_candidate,18679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20447,curation_candidate,18906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20448,curation_candidate,19126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20449,curation_candidate,19340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20450,curation_candidate,19364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20451,curation_candidate,19377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20452,curation_candidate,19412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20453,curation_candidate,19470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20454,curation_candidate,19503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20455,curation_candidate,19728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20456,curation_candidate,19762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20457,curation_candidate,19863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20458,curation_candidate,20106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20459,curation_candidate,20187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20460,curation_candidate,20228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20461,curation_candidate,20230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20462,curation_candidate,20374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20463,curation_candidate,20795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20464,curation_candidate,20806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20465,curation_candidate,20832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20466,curation_candidate,20917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20467,curation_candidate,20957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20468,curation_candidate,21053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20469,curation_candidate,21196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20470,curation_candidate,21216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20471,curation_candidate,21289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20472,curation_candidate,21295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20473,curation_candidate,21413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20474,curation_candidate,21445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20475,curation_candidate,21679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20476,curation_candidate,21710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20477,curation_candidate,21784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20478,curation_candidate,21791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20479,curation_candidate,21954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20480,curation_candidate,22055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20481,curation_candidate,22080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20482,curation_candidate,22180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20483,curation_candidate,22628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20484,curation_candidate,22923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20485,curation_candidate,22979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20486,curation_candidate,23064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20487,curation_candidate,23151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20488,curation_candidate,23205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20489,curation_candidate,23238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20490,curation_candidate,23359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20491,curation_candidate,23374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20492,curation_candidate,23447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20493,curation_candidate,23562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20494,curation_candidate,23801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20495,curation_candidate,23965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20496,curation_candidate,24034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20497,curation_candidate,24101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
20498,curation_candidate,24212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20499,curation_candidate,24332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20500,curation_candidate,24346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20501,curation_candidate,24472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20502,curation_candidate,24511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20503,curation_candidate,24599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20504,curation_candidate,24664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20505,curation_candidate,24799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20506,curation_candidate,24817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20507,curation_candidate,24818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20508,curation_candidate,24982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20509,curation_candidate,25252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20510,curation_candidate,25455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20511,curation_candidate,25556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20512,curation_candidate,25597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20513,curation_candidate,25638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20514,curation_candidate,25678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20515,curation_candidate,25876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20516,curation_candidate,25903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20517,curation_candidate,26199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20518,curation_candidate,26204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20519,curation_candidate,26641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20520,curation_candidate,26975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20521,curation_candidate,27001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20522,curation_candidate,27009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20523,curation_candidate,27092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20524,curation_candidate,27149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20525,curation_candidate,27161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20526,curation_candidate,27226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20527,curation_candidate,27249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20528,curation_candidate,27354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20529,curation_candidate,27452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20530,curation_candidate,27520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20531,curation_candidate,27839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20532,curation_candidate,28137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20533,curation_candidate,28210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20534,curation_candidate,28273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20535,curation_candidate,28350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20536,curation_candidate,28787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20537,curation_candidate,28914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20538,curation_candidate,29307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20539,curation_candidate,29396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20540,curation_candidate,29425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20541,curation_candidate,29593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20542,curation_candidate,29760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20543,curation_candidate,30003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20544,curation_candidate,30060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20545,curation_candidate,30652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20546,curation_candidate,30672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20547,curation_candidate,30735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20548,curation_candidate,30837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20549,curation_candidate,30838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20550,curation_candidate,30888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20551,curation_candidate,30893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20552,curation_candidate,30924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20553,curation_candidate,30959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20554,curation_candidate,31213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20555,curation_candidate,31496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20556,curation_candidate,31590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20557,curation_candidate,31624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20558,curation_candidate,31701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20559,curation_candidate,31724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20560,curation_candidate,31731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20561,curation_candidate,31786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20562,curation_candidate,32053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20563,curation_candidate,32202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20564,curation_candidate,32226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20565,curation_candidate,32302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20566,curation_candidate,32461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20567,curation_candidate,32496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20568,curation_candidate,32540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20569,curation_candidate,32584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20570,curation_candidate,32587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20571,curation_candidate,32713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20572,curation_candidate,32836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20573,curation_candidate,32839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20574,curation_candidate,32933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20575,curation_candidate,32943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20576,curation_candidate,33163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20577,curation_candidate,33170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20578,curation_candidate,33221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20579,curation_candidate,33275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20580,curation_candidate,33312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20581,curation_candidate,33316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20582,curation_candidate,33409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
20583,curation_candidate,33566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20584,curation_candidate,33642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20585,curation_candidate,33704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20586,curation_candidate,33730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20587,curation_candidate,33743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20588,curation_candidate,33861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20589,curation_candidate,34006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20590,curation_candidate,34113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20591,curation_candidate,34246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20592,curation_candidate,34259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20593,curation_candidate,34275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20594,curation_candidate,34292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20595,curation_candidate,34299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20596,curation_candidate,34673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20597,curation_candidate,34763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20598,curation_candidate,34785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20599,curation_candidate,34963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20600,curation_candidate,35220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20601,curation_candidate,35284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20602,curation_candidate,35308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20603,curation_candidate,35397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20604,curation_candidate,35437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20605,curation_candidate,35519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20606,curation_candidate,35678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20607,curation_candidate,35764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20608,curation_candidate,35768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20609,curation_candidate,35818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20610,curation_candidate,35954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20611,curation_candidate,35980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20612,curation_candidate,35985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20613,curation_candidate,35995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20614,curation_candidate,36089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20615,curation_candidate,36318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20616,curation_candidate,36349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20617,curation_candidate,36371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20618,curation_candidate,36406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20619,curation_candidate,36860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20620,curation_candidate,37018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20621,curation_candidate,37179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20622,curation_candidate,37508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20623,curation_candidate,37743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20624,curation_candidate,37967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20625,curation_candidate,38059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20626,curation_candidate,38260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20627,curation_candidate,16416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20628,curation_candidate,16530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20629,curation_candidate,16637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20630,curation_candidate,16888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20631,curation_candidate,17124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20632,curation_candidate,17168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20633,curation_candidate,17482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20634,curation_candidate,17608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20635,curation_candidate,17668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20636,curation_candidate,17784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20637,curation_candidate,17987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20638,curation_candidate,17999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20639,curation_candidate,18032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20640,curation_candidate,18193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20641,curation_candidate,18456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20642,curation_candidate,18630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20643,curation_candidate,18659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20644,curation_candidate,18672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20645,curation_candidate,18774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
20646,curation_candidate,18848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20647,curation_candidate,19109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20648,curation_candidate,19140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20649,curation_candidate,19319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20650,curation_candidate,19320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20651,curation_candidate,19368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20652,curation_candidate,19404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20653,curation_candidate,19577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20654,curation_candidate,19632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20655,curation_candidate,19681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20656,curation_candidate,19975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20657,curation_candidate,19980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20658,curation_candidate,20123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20659,curation_candidate,20136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20660,curation_candidate,20359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20661,curation_candidate,20366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20662,curation_candidate,20436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20663,curation_candidate,21131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20664,curation_candidate,21224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20665,curation_candidate,21283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20666,curation_candidate,21347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20667,curation_candidate,21370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20668,curation_candidate,21463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20669,curation_candidate,21598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20670,curation_candidate,21628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20671,curation_candidate,21648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20672,curation_candidate,21666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20673,curation_candidate,21725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20674,curation_candidate,21811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20675,curation_candidate,21920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20676,curation_candidate,21971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20677,curation_candidate,21974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20678,curation_candidate,22006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20679,curation_candidate,22148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20680,curation_candidate,22288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20681,curation_candidate,22323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20682,curation_candidate,22453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20683,curation_candidate,22473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20684,curation_candidate,22716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20685,curation_candidate,22874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20686,curation_candidate,23111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20687,curation_candidate,23132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20688,curation_candidate,23516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20689,curation_candidate,23576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20690,curation_candidate,23648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20691,curation_candidate,23738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20692,curation_candidate,24080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20693,curation_candidate,24241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20694,curation_candidate,24514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20695,curation_candidate,24898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20696,curation_candidate,25045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20697,curation_candidate,25222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20698,curation_candidate,25231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20699,curation_candidate,25319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20700,curation_candidate,25586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20701,curation_candidate,26014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20702,curation_candidate,26181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20703,curation_candidate,26262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20704,curation_candidate,26551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20705,curation_candidate,26668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20706,curation_candidate,26823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20707,curation_candidate,26985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20708,curation_candidate,27373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20709,curation_candidate,27546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20710,curation_candidate,27715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20711,curation_candidate,27735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20712,curation_candidate,27757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20713,curation_candidate,27764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20714,curation_candidate,27973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20715,curation_candidate,28089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20716,curation_candidate,28288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20717,curation_candidate,28425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20718,curation_candidate,28498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20719,curation_candidate,28580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20720,curation_candidate,28908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20721,curation_candidate,29257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20722,curation_candidate,29466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20723,curation_candidate,29833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20724,curation_candidate,30179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20725,curation_candidate,30734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20726,curation_candidate,30805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
20727,curation_candidate,30921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20728,curation_candidate,31216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20729,curation_candidate,31217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20730,curation_candidate,31403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20731,curation_candidate,31560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20732,curation_candidate,31597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20733,curation_candidate,31603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20734,curation_candidate,31706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20735,curation_candidate,31787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20736,curation_candidate,31841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20737,curation_candidate,31843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20738,curation_candidate,31849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20739,curation_candidate,31858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20740,curation_candidate,31864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20741,curation_candidate,31946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20742,curation_candidate,31961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20743,curation_candidate,32151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20744,curation_candidate,32157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20745,curation_candidate,32361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20746,curation_candidate,32458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20747,curation_candidate,32459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20748,curation_candidate,32466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20749,curation_candidate,32679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20750,curation_candidate,32805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20751,curation_candidate,32868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20752,curation_candidate,32881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20753,curation_candidate,33071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20754,curation_candidate,33145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20755,curation_candidate,33155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20756,curation_candidate,33357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20757,curation_candidate,33416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20758,curation_candidate,33450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20759,curation_candidate,34159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20760,curation_candidate,34315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20761,curation_candidate,34341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20762,curation_candidate,34458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20763,curation_candidate,34597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20764,curation_candidate,34616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20765,curation_candidate,34672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20766,curation_candidate,35144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20767,curation_candidate,35145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20768,curation_candidate,35652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20769,curation_candidate,35855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20770,curation_candidate,36389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20771,curation_candidate,36661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20772,curation_candidate,36696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20773,curation_candidate,36747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20774,curation_candidate,16480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20775,curation_candidate,16537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20776,curation_candidate,16779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20777,curation_candidate,16882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20778,curation_candidate,17032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20779,curation_candidate,17146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20780,curation_candidate,17166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20781,curation_candidate,17190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20782,curation_candidate,17264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20783,curation_candidate,17570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20784,curation_candidate,17672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20785,curation_candidate,17723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
20786,curation_candidate,17726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20787,curation_candidate,17958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20788,curation_candidate,17991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20789,curation_candidate,18143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20790,curation_candidate,18308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20791,curation_candidate,18332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20792,curation_candidate,18544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20793,curation_candidate,18577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20794,curation_candidate,18617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20795,curation_candidate,18629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20796,curation_candidate,19008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20797,curation_candidate,19056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20798,curation_candidate,19111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20799,curation_candidate,19114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20800,curation_candidate,19456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20801,curation_candidate,19519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20802,curation_candidate,19890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20803,curation_candidate,19986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20804,curation_candidate,20034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20805,curation_candidate,20096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20806,curation_candidate,20274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20807,curation_candidate,20396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20808,curation_candidate,20502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20809,curation_candidate,20518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20810,curation_candidate,20582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20811,curation_candidate,20858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20812,curation_candidate,21188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20813,curation_candidate,21207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20814,curation_candidate,21244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20815,curation_candidate,21304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20816,curation_candidate,21312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20817,curation_candidate,21630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20818,curation_candidate,21671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20819,curation_candidate,21682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20820,curation_candidate,21887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20821,curation_candidate,21940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20822,curation_candidate,21966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20823,curation_candidate,22121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20824,curation_candidate,22158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
20825,curation_candidate,22275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20826,curation_candidate,22291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20827,curation_candidate,22534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20828,curation_candidate,22744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20829,curation_candidate,22821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20830,curation_candidate,22934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20831,curation_candidate,22982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20832,curation_candidate,23324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20833,curation_candidate,23391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20834,curation_candidate,23492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20835,curation_candidate,23548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20836,curation_candidate,23699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20837,curation_candidate,23731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20838,curation_candidate,24261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20839,curation_candidate,24308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20840,curation_candidate,24411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20841,curation_candidate,24448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20842,curation_candidate,24489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20843,curation_candidate,24640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20844,curation_candidate,24669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20845,curation_candidate,24986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20846,curation_candidate,25109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20847,curation_candidate,25116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20848,curation_candidate,25202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20849,curation_candidate,25485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20850,curation_candidate,25893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20851,curation_candidate,25910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20852,curation_candidate,25937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20853,curation_candidate,25942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
20854,curation_candidate,25983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20855,curation_candidate,26385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20856,curation_candidate,26886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20857,curation_candidate,26981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20858,curation_candidate,27231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20859,curation_candidate,27293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20860,curation_candidate,27627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20861,curation_candidate,27812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20862,curation_candidate,28525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20863,curation_candidate,29801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20864,curation_candidate,29841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20865,curation_candidate,29912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20866,curation_candidate,30026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20867,curation_candidate,30030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20868,curation_candidate,30057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
20869,curation_candidate,30064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20870,curation_candidate,30132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20871,curation_candidate,30176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20872,curation_candidate,30281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20873,curation_candidate,30294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20874,curation_candidate,30324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20875,curation_candidate,30327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20876,curation_candidate,30389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20877,curation_candidate,30455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20878,curation_candidate,30635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20879,curation_candidate,30922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20880,curation_candidate,31072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20881,curation_candidate,31087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20882,curation_candidate,31089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20883,curation_candidate,31181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20884,curation_candidate,31232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20885,curation_candidate,31275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20886,curation_candidate,31383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20887,curation_candidate,31386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20888,curation_candidate,31463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20889,curation_candidate,31520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20890,curation_candidate,31602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20891,curation_candidate,31784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20892,curation_candidate,31799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20893,curation_candidate,31895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20894,curation_candidate,31898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20895,curation_candidate,31911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20896,curation_candidate,31973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20897,curation_candidate,32073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20898,curation_candidate,32166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20899,curation_candidate,32230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20900,curation_candidate,32275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20901,curation_candidate,32287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20902,curation_candidate,32373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20903,curation_candidate,32499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20904,curation_candidate,32502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20905,curation_candidate,32525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20906,curation_candidate,32534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20907,curation_candidate,32663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20908,curation_candidate,32734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20909,curation_candidate,32754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20910,curation_candidate,32915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20911,curation_candidate,33103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20912,curation_candidate,33220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20913,curation_candidate,33296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20914,curation_candidate,33403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20915,curation_candidate,33433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20916,curation_candidate,33586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20917,curation_candidate,33620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
20918,curation_candidate,33731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20919,curation_candidate,33972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20920,curation_candidate,33996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20921,curation_candidate,34016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20922,curation_candidate,34035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20923,curation_candidate,34052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20924,curation_candidate,34062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20925,curation_candidate,34140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20926,curation_candidate,34421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20927,curation_candidate,34450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20928,curation_candidate,34754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20929,curation_candidate,34836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20930,curation_candidate,35035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20931,curation_candidate,35181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20932,curation_candidate,35208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20933,curation_candidate,35269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20934,curation_candidate,35279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20935,curation_candidate,35391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20936,curation_candidate,35496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20937,curation_candidate,35666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20938,curation_candidate,35771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20939,curation_candidate,35784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20940,curation_candidate,35864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20941,curation_candidate,35910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20942,curation_candidate,36168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20943,curation_candidate,36275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20944,curation_candidate,36344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20945,curation_candidate,36570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20946,curation_candidate,36601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20947,curation_candidate,36792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
20948,curation_candidate,36848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20949,curation_candidate,36895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20950,curation_candidate,36951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20951,curation_candidate,37203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20952,curation_candidate,37327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20953,curation_candidate,37893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20954,curation_candidate,38021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20955,curation_candidate,38179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20956,curation_candidate,16460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
20957,curation_candidate,16589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20958,curation_candidate,16621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20959,curation_candidate,16793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20960,curation_candidate,17120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20961,curation_candidate,17149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20962,curation_candidate,17252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20963,curation_candidate,17320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20964,curation_candidate,17678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20965,curation_candidate,17956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20966,curation_candidate,18168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20967,curation_candidate,18184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20968,curation_candidate,18512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20969,curation_candidate,18585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20970,curation_candidate,18907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20971,curation_candidate,18916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20972,curation_candidate,19066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20973,curation_candidate,19161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20974,curation_candidate,19537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20975,curation_candidate,19655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20976,curation_candidate,19700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20977,curation_candidate,19795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20978,curation_candidate,19936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20979,curation_candidate,20147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20980,curation_candidate,20236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20981,curation_candidate,20538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20982,curation_candidate,20692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20983,curation_candidate,20729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20984,curation_candidate,20732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20985,curation_candidate,20968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20986,curation_candidate,21068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20987,curation_candidate,21313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20988,curation_candidate,21330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20989,curation_candidate,21523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
20990,curation_candidate,21656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20991,curation_candidate,22082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20992,curation_candidate,22573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20993,curation_candidate,22612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20994,curation_candidate,24230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20995,curation_candidate,24493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
20996,curation_candidate,24612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
20997,curation_candidate,25042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
20998,curation_candidate,25926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
20999,curation_candidate,25929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21000,curation_candidate,25998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21001,curation_candidate,26555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21002,curation_candidate,26566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21003,curation_candidate,26857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21004,curation_candidate,27028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21005,curation_candidate,27080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21006,curation_candidate,27184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21007,curation_candidate,27407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21008,curation_candidate,28276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21009,curation_candidate,28403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21010,curation_candidate,28438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21011,curation_candidate,28579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21012,curation_candidate,28850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21013,curation_candidate,29838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
21014,curation_candidate,29853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21015,curation_candidate,29901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21016,curation_candidate,29922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21017,curation_candidate,30001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21018,curation_candidate,30027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21019,curation_candidate,30141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21020,curation_candidate,30563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21021,curation_candidate,30629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21022,curation_candidate,30671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21023,curation_candidate,30693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21024,curation_candidate,30824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21025,curation_candidate,30918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21026,curation_candidate,30945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21027,curation_candidate,31027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21028,curation_candidate,31080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21029,curation_candidate,31084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21030,curation_candidate,31126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21031,curation_candidate,31150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21032,curation_candidate,31242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21033,curation_candidate,31328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21034,curation_candidate,31469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21035,curation_candidate,31497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21036,curation_candidate,31663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21037,curation_candidate,31859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21038,curation_candidate,31932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21039,curation_candidate,32114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21040,curation_candidate,32164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21041,curation_candidate,32478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21042,curation_candidate,32563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21043,curation_candidate,32574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21044,curation_candidate,32872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21045,curation_candidate,32910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21046,curation_candidate,32956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21047,curation_candidate,33215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21048,curation_candidate,33332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21049,curation_candidate,33448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21050,curation_candidate,33542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21051,curation_candidate,33797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21052,curation_candidate,33840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21053,curation_candidate,33906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21054,curation_candidate,33940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21055,curation_candidate,34096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21056,curation_candidate,34200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21057,curation_candidate,34342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21058,curation_candidate,34358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21059,curation_candidate,34453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21060,curation_candidate,34503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21061,curation_candidate,34779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21062,curation_candidate,34934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21063,curation_candidate,34940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21064,curation_candidate,34944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21065,curation_candidate,35051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21066,curation_candidate,35139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21067,curation_candidate,35254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21068,curation_candidate,35576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21069,curation_candidate,35625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21070,curation_candidate,35673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21071,curation_candidate,35845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21072,curation_candidate,35871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21073,curation_candidate,35955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21074,curation_candidate,35983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21075,curation_candidate,36037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21076,curation_candidate,36148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21077,curation_candidate,36169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21078,curation_candidate,36339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21079,curation_candidate,36507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21080,curation_candidate,36622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21081,curation_candidate,36723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21082,curation_candidate,36772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21083,curation_candidate,36791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21084,curation_candidate,36796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21085,curation_candidate,36958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21086,curation_candidate,37095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21087,curation_candidate,37594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21088,curation_candidate,37922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21089,curation_candidate,38022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21090,curation_candidate,38118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21091,curation_candidate,38221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21092,curation_candidate,38265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21093,curation_candidate,17472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21094,curation_candidate,18150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21095,curation_candidate,18443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21096,curation_candidate,18556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21097,curation_candidate,19028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21098,curation_candidate,19051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21099,curation_candidate,19290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21100,curation_candidate,19790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21101,curation_candidate,20133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21102,curation_candidate,20484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21103,curation_candidate,20663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21104,curation_candidate,20678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21105,curation_candidate,21269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21106,curation_candidate,21538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21107,curation_candidate,21626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21108,curation_candidate,21637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21109,curation_candidate,21874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21110,curation_candidate,22179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21111,curation_candidate,22520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21112,curation_candidate,23007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21113,curation_candidate,23079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21114,curation_candidate,23753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21115,curation_candidate,23841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21116,curation_candidate,24151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21117,curation_candidate,24191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21118,curation_candidate,24852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21119,curation_candidate,25864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21120,curation_candidate,26401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21121,curation_candidate,26687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21122,curation_candidate,27661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21123,curation_candidate,28235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21124,curation_candidate,28485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21125,curation_candidate,29943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
21126,curation_candidate,30372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21127,curation_candidate,30800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21128,curation_candidate,30834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21129,curation_candidate,30841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21130,curation_candidate,30976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21131,curation_candidate,31474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21132,curation_candidate,31522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21133,curation_candidate,31737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21134,curation_candidate,31890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21135,curation_candidate,31948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21136,curation_candidate,31974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21137,curation_candidate,32032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21138,curation_candidate,32186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21139,curation_candidate,32291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21140,curation_candidate,32483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21141,curation_candidate,32644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21142,curation_candidate,32672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21143,curation_candidate,32798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21144,curation_candidate,32939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21145,curation_candidate,33257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21146,curation_candidate,33279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21147,curation_candidate,33371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21148,curation_candidate,33726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21149,curation_candidate,33751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21150,curation_candidate,33794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21151,curation_candidate,33823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21152,curation_candidate,34001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21153,curation_candidate,34049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21154,curation_candidate,34068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21155,curation_candidate,34235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21156,curation_candidate,34789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21157,curation_candidate,34799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21158,curation_candidate,35185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21159,curation_candidate,35274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21160,curation_candidate,35399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21161,curation_candidate,35495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21162,curation_candidate,35536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21163,curation_candidate,35626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21164,curation_candidate,35667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21165,curation_candidate,35681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21166,curation_candidate,35691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21167,curation_candidate,35795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21168,curation_candidate,36125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21169,curation_candidate,36225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21170,curation_candidate,36441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21171,curation_candidate,36460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21172,curation_candidate,36755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21173,curation_candidate,37536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21174,curation_candidate,37727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21175,curation_candidate,37761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21176,curation_candidate,37807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21177,curation_candidate,37950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21178,curation_candidate,17026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21179,curation_candidate,17495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21180,curation_candidate,17728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21181,curation_candidate,17791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21182,curation_candidate,18016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21183,curation_candidate,18706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21184,curation_candidate,19062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21185,curation_candidate,19182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21186,curation_candidate,19313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21187,curation_candidate,19381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21188,curation_candidate,19807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21189,curation_candidate,20932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21190,curation_candidate,21992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21191,curation_candidate,22108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21192,curation_candidate,22173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21193,curation_candidate,22297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21194,curation_candidate,23148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21195,curation_candidate,24657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21196,curation_candidate,24959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21197,curation_candidate,26631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21198,curation_candidate,27245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21199,curation_candidate,29878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21200,curation_candidate,29898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
21201,curation_candidate,30191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21202,curation_candidate,30222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
21203,curation_candidate,31180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21204,curation_candidate,31355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21205,curation_candidate,31385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21206,curation_candidate,31413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21207,curation_candidate,31427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21208,curation_candidate,31483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21209,curation_candidate,31728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21210,curation_candidate,31835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21211,curation_candidate,32306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21212,curation_candidate,32602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21213,curation_candidate,32774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21214,curation_candidate,32811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21215,curation_candidate,32869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21216,curation_candidate,33113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21217,curation_candidate,33482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21218,curation_candidate,33605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21219,curation_candidate,33679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21220,curation_candidate,33711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21221,curation_candidate,33936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21222,curation_candidate,33980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21223,curation_candidate,34329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21224,curation_candidate,34372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21225,curation_candidate,34394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21226,curation_candidate,34404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21227,curation_candidate,34498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21228,curation_candidate,34520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21229,curation_candidate,34586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21230,curation_candidate,34647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21231,curation_candidate,34736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21232,curation_candidate,34865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21233,curation_candidate,34973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21234,curation_candidate,35250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21235,curation_candidate,35339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21236,curation_candidate,35410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21237,curation_candidate,35476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21238,curation_candidate,35485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21239,curation_candidate,35551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21240,curation_candidate,35938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21241,curation_candidate,36112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21242,curation_candidate,36388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21243,curation_candidate,36500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21244,curation_candidate,37154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21245,curation_candidate,37158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
21246,curation_candidate,37728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21247,curation_candidate,38050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21248,curation_candidate,38114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21249,curation_candidate,16966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21250,curation_candidate,18364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21251,curation_candidate,19034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21252,curation_candidate,19052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21253,curation_candidate,23347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21254,curation_candidate,24608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21255,curation_candidate,28551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21256,curation_candidate,29874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21257,curation_candidate,29998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21258,curation_candidate,30108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
21259,curation_candidate,30120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21260,curation_candidate,30129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21261,curation_candidate,30285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21262,curation_candidate,30291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21263,curation_candidate,30310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21264,curation_candidate,30473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21265,curation_candidate,30489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21266,curation_candidate,30544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21267,curation_candidate,30620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21268,curation_candidate,30660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21269,curation_candidate,30861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21270,curation_candidate,31233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21271,curation_candidate,31336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21272,curation_candidate,31459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21273,curation_candidate,31517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21274,curation_candidate,31521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21275,curation_candidate,31683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21276,curation_candidate,31802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21277,curation_candidate,32170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21278,curation_candidate,32210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21279,curation_candidate,32215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21280,curation_candidate,32223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21281,curation_candidate,32224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21282,curation_candidate,32379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21283,curation_candidate,32612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21284,curation_candidate,33011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21285,curation_candidate,33162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21286,curation_candidate,33577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21287,curation_candidate,33616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21288,curation_candidate,33860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21289,curation_candidate,33870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21290,curation_candidate,34493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21291,curation_candidate,34519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21292,curation_candidate,34987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21293,curation_candidate,35123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21294,curation_candidate,35334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21295,curation_candidate,35411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21296,curation_candidate,35493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21297,curation_candidate,35533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21298,curation_candidate,35552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21299,curation_candidate,35865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21300,curation_candidate,36442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21301,curation_candidate,36531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21302,curation_candidate,36738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21303,curation_candidate,36801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21304,curation_candidate,37220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21305,curation_candidate,37630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21306,curation_candidate,37631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21307,curation_candidate,37731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21308,curation_candidate,37767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21309,curation_candidate,37833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21310,curation_candidate,38174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21311,curation_candidate,38175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21312,curation_candidate,38241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21313,curation_candidate,38314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21314,curation_candidate,28430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21315,curation_candidate,28448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21316,curation_candidate,29914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21317,curation_candidate,30054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21318,curation_candidate,30414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21319,curation_candidate,30456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21320,curation_candidate,31095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21321,curation_candidate,31239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21322,curation_candidate,31303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21323,curation_candidate,31889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21324,curation_candidate,32059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21325,curation_candidate,32140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
21326,curation_candidate,32167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21327,curation_candidate,32294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21328,curation_candidate,32380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21329,curation_candidate,32890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21330,curation_candidate,32942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21331,curation_candidate,32950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21332,curation_candidate,33252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21333,curation_candidate,33350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21334,curation_candidate,33402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21335,curation_candidate,33437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21336,curation_candidate,33820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21337,curation_candidate,33883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21338,curation_candidate,33919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21339,curation_candidate,33976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21340,curation_candidate,34127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21341,curation_candidate,34314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21342,curation_candidate,34369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21343,curation_candidate,34432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21344,curation_candidate,34801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21345,curation_candidate,34962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21346,curation_candidate,35053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21347,curation_candidate,35191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21348,curation_candidate,35197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21349,curation_candidate,35836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21350,curation_candidate,35982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21351,curation_candidate,36291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21352,curation_candidate,36313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21353,curation_candidate,36417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21354,curation_candidate,36675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21355,curation_candidate,37604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21356,curation_candidate,37931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21357,curation_candidate,37932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21358,curation_candidate,37934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21359,curation_candidate,38004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21360,curation_candidate,38089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21361,curation_candidate,38136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21362,curation_candidate,38190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21363,curation_candidate,29981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21364,curation_candidate,30020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21365,curation_candidate,30239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21366,curation_candidate,30432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21367,curation_candidate,30847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21368,curation_candidate,31326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21369,curation_candidate,31487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21370,curation_candidate,31678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21371,curation_candidate,32747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21372,curation_candidate,32894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21373,curation_candidate,33092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21374,curation_candidate,33262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21375,curation_candidate,33426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21376,curation_candidate,33428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21377,curation_candidate,33473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21378,curation_candidate,33909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21379,curation_candidate,33939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21380,curation_candidate,33975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21381,curation_candidate,33985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21382,curation_candidate,34163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21383,curation_candidate,34797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21384,curation_candidate,35010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21385,curation_candidate,35206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21386,curation_candidate,35265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21387,curation_candidate,35341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21388,curation_candidate,35535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21389,curation_candidate,35574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21390,curation_candidate,35624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21391,curation_candidate,35682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21392,curation_candidate,35704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21393,curation_candidate,35708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21394,curation_candidate,35739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21395,curation_candidate,36366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21396,curation_candidate,36444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21397,curation_candidate,36835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21398,curation_candidate,37073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21399,curation_candidate,38049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21400,curation_candidate,38242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21401,curation_candidate,38275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21402,curation_candidate,30171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21403,curation_candidate,30184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21404,curation_candidate,30440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21405,curation_candidate,30444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21406,curation_candidate,30556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21407,curation_candidate,31083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21408,curation_candidate,31296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21409,curation_candidate,31533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21410,curation_candidate,31546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21411,curation_candidate,31618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21412,curation_candidate,31917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21413,curation_candidate,32072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21414,curation_candidate,32234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21415,curation_candidate,32289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21416,curation_candidate,32508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21417,curation_candidate,32547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21418,curation_candidate,32815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21419,curation_candidate,32970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21420,curation_candidate,33107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21421,curation_candidate,33249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21422,curation_candidate,33369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21423,curation_candidate,33582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21424,curation_candidate,33804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21425,curation_candidate,33964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21426,curation_candidate,33997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21427,curation_candidate,34166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21428,curation_candidate,34269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21429,curation_candidate,34412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21430,curation_candidate,34442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21431,curation_candidate,34722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21432,curation_candidate,34887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21433,curation_candidate,35037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21434,curation_candidate,35057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21435,curation_candidate,35234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21436,curation_candidate,35335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21437,curation_candidate,35592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21438,curation_candidate,35715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21439,curation_candidate,35988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21440,curation_candidate,36060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21441,curation_candidate,36099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21442,curation_candidate,36214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21443,curation_candidate,36266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21444,curation_candidate,36724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21445,curation_candidate,36964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21446,curation_candidate,37211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21447,curation_candidate,37354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21448,curation_candidate,37418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21449,curation_candidate,37488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21450,curation_candidate,37546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21451,curation_candidate,37599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21452,curation_candidate,37600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21453,curation_candidate,37735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21454,curation_candidate,37748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21455,curation_candidate,37806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21456,curation_candidate,37836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21457,curation_candidate,38011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21458,curation_candidate,38077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21459,curation_candidate,38078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21460,curation_candidate,38178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21461,curation_candidate,21418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21462,curation_candidate,22580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21463,curation_candidate,29368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21464,curation_candidate,29482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21465,curation_candidate,29514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21466,curation_candidate,29526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21467,curation_candidate,35004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21468,curation_candidate,36307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21469,curation_candidate,16466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21470,curation_candidate,17025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21471,curation_candidate,17496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21472,curation_candidate,17787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21473,curation_candidate,18315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21474,curation_candidate,18484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21475,curation_candidate,19081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21476,curation_candidate,19099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21477,curation_candidate,19390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21478,curation_candidate,19407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21479,curation_candidate,19656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21480,curation_candidate,20215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21481,curation_candidate,20428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21482,curation_candidate,20439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21483,curation_candidate,20828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21484,curation_candidate,20958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21485,curation_candidate,21885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21486,curation_candidate,22009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21487,curation_candidate,22945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21488,curation_candidate,23458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21489,curation_candidate,23509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21490,curation_candidate,24508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21491,curation_candidate,24583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21492,curation_candidate,25286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21493,curation_candidate,25522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21494,curation_candidate,25646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21495,curation_candidate,26471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21496,curation_candidate,27645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21497,curation_candidate,28064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21498,curation_candidate,28653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21499,curation_candidate,29055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21500,curation_candidate,29311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21501,curation_candidate,29595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21502,curation_candidate,29644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
21503,curation_candidate,29709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21504,curation_candidate,29724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21505,curation_candidate,32076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21506,curation_candidate,32188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21507,curation_candidate,32356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21508,curation_candidate,32359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21509,curation_candidate,32610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21510,curation_candidate,34832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21511,curation_candidate,35404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21512,curation_candidate,36245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21513,curation_candidate,36729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21514,curation_candidate,37430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21515,curation_candidate,17135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21516,curation_candidate,17277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21517,curation_candidate,17405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21518,curation_candidate,17693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21519,curation_candidate,17761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21520,curation_candidate,18328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21521,curation_candidate,18555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21522,curation_candidate,18685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21523,curation_candidate,18779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21524,curation_candidate,18897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21525,curation_candidate,18983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21526,curation_candidate,19437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21527,curation_candidate,19609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21528,curation_candidate,19798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21529,curation_candidate,19802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21530,curation_candidate,19908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21531,curation_candidate,20007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21532,curation_candidate,20227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21533,curation_candidate,20303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21534,curation_candidate,20335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21535,curation_candidate,20353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21536,curation_candidate,20698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21537,curation_candidate,20910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21538,curation_candidate,21200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21539,curation_candidate,21307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21540,curation_candidate,21505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21541,curation_candidate,21852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21542,curation_candidate,22069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21543,curation_candidate,22541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21544,curation_candidate,22677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21545,curation_candidate,22797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21546,curation_candidate,22820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21547,curation_candidate,22922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21548,curation_candidate,22932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21549,curation_candidate,22988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21550,curation_candidate,23024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21551,curation_candidate,23133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21552,curation_candidate,23270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21553,curation_candidate,23375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21554,curation_candidate,23541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21555,curation_candidate,23620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21556,curation_candidate,23930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21557,curation_candidate,23946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21558,curation_candidate,23959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21559,curation_candidate,24064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21560,curation_candidate,24277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21561,curation_candidate,24416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21562,curation_candidate,24422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21563,curation_candidate,24942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21564,curation_candidate,25008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21565,curation_candidate,25161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21566,curation_candidate,25533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21567,curation_candidate,25542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21568,curation_candidate,25950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21569,curation_candidate,25979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21570,curation_candidate,26174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21571,curation_candidate,26176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21572,curation_candidate,26219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21573,curation_candidate,26647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21574,curation_candidate,26653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21575,curation_candidate,26714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21576,curation_candidate,27337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21577,curation_candidate,27339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21578,curation_candidate,27701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
21579,curation_candidate,28257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21580,curation_candidate,28427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21581,curation_candidate,28581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21582,curation_candidate,28640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21583,curation_candidate,28846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21584,curation_candidate,28943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21585,curation_candidate,28976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21586,curation_candidate,29033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21587,curation_candidate,29095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21588,curation_candidate,29247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21589,curation_candidate,29320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21590,curation_candidate,29339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21591,curation_candidate,29340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21592,curation_candidate,29351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21593,curation_candidate,29379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21594,curation_candidate,29416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21595,curation_candidate,29487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21596,curation_candidate,29516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21597,curation_candidate,29521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21598,curation_candidate,29544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21599,curation_candidate,29552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21600,curation_candidate,29574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21601,curation_candidate,29614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21602,curation_candidate,29621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21603,curation_candidate,29632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21604,curation_candidate,29685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21605,curation_candidate,29711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21606,curation_candidate,29761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21607,curation_candidate,29825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21608,curation_candidate,31684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21609,curation_candidate,31742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21610,curation_candidate,32342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21611,curation_candidate,33005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21612,curation_candidate,33805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21613,curation_candidate,35158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21614,curation_candidate,36445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21615,curation_candidate,36898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21616,curation_candidate,37682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21617,curation_candidate,16331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21618,curation_candidate,16978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21619,curation_candidate,17367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21620,curation_candidate,17670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21621,curation_candidate,17747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21622,curation_candidate,17805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21623,curation_candidate,17994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21624,curation_candidate,18165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21625,curation_candidate,18439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21626,curation_candidate,18728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21627,curation_candidate,18729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21628,curation_candidate,18908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21629,curation_candidate,19536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21630,curation_candidate,19978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21631,curation_candidate,20030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21632,curation_candidate,20208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21633,curation_candidate,20412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21634,curation_candidate,20444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21635,curation_candidate,20740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21636,curation_candidate,20812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21637,curation_candidate,20921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21638,curation_candidate,21249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21639,curation_candidate,21691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21640,curation_candidate,22056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21641,curation_candidate,22229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21642,curation_candidate,22450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21643,curation_candidate,22561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21644,curation_candidate,22658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21645,curation_candidate,23124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21646,curation_candidate,23196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21647,curation_candidate,23231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21648,curation_candidate,23321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21649,curation_candidate,23398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21650,curation_candidate,23403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21651,curation_candidate,23525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21652,curation_candidate,23591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21653,curation_candidate,23701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21654,curation_candidate,23714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21655,curation_candidate,23867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21656,curation_candidate,24021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21657,curation_candidate,24030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21658,curation_candidate,24031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21659,curation_candidate,24077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21660,curation_candidate,24186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21661,curation_candidate,24235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21662,curation_candidate,24278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21663,curation_candidate,24424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21664,curation_candidate,24482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21665,curation_candidate,24540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21666,curation_candidate,24630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21667,curation_candidate,24827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21668,curation_candidate,25120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21669,curation_candidate,25153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21670,curation_candidate,25356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21671,curation_candidate,25458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21672,curation_candidate,25459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21673,curation_candidate,25589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21674,curation_candidate,25642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21675,curation_candidate,25690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21676,curation_candidate,25763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21677,curation_candidate,25943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21678,curation_candidate,26010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21679,curation_candidate,26153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21680,curation_candidate,26434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21681,curation_candidate,26469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21682,curation_candidate,26602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21683,curation_candidate,27216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21684,curation_candidate,27593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21685,curation_candidate,27872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21686,curation_candidate,28015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21687,curation_candidate,28272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21688,curation_candidate,28305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21689,curation_candidate,28415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21690,curation_candidate,28566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21691,curation_candidate,28702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21692,curation_candidate,28845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21693,curation_candidate,29026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21694,curation_candidate,29061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21695,curation_candidate,29181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21696,curation_candidate,29199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21697,curation_candidate,29200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21698,curation_candidate,29306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21699,curation_candidate,29338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21700,curation_candidate,29430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21701,curation_candidate,29437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21702,curation_candidate,29515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21703,curation_candidate,29527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21704,curation_candidate,29702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21705,curation_candidate,29742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21706,curation_candidate,29784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21707,curation_candidate,29803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21708,curation_candidate,30612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21709,curation_candidate,30916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21710,curation_candidate,31085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21711,curation_candidate,31555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21712,curation_candidate,32150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21713,curation_candidate,36044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21714,curation_candidate,36684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21715,curation_candidate,37827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21716,curation_candidate,16346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21717,curation_candidate,16557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21718,curation_candidate,16622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21719,curation_candidate,16890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21720,curation_candidate,17326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21721,curation_candidate,17393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21722,curation_candidate,17578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21723,curation_candidate,17641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21724,curation_candidate,18118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21725,curation_candidate,18500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21726,curation_candidate,18877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21727,curation_candidate,18978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21728,curation_candidate,19060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21729,curation_candidate,19174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21730,curation_candidate,19225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21731,curation_candidate,19625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21732,curation_candidate,19747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21733,curation_candidate,19806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21734,curation_candidate,19864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21735,curation_candidate,19871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21736,curation_candidate,19963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21737,curation_candidate,20232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21738,curation_candidate,20404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21739,curation_candidate,20425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21740,curation_candidate,20511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21741,curation_candidate,20689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21742,curation_candidate,20717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21743,curation_candidate,20727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21744,curation_candidate,20943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21745,curation_candidate,21262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21746,curation_candidate,21263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21747,curation_candidate,21431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21748,curation_candidate,21782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21749,curation_candidate,21829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21750,curation_candidate,21890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21751,curation_candidate,21942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21752,curation_candidate,22090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21753,curation_candidate,22220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21754,curation_candidate,22284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
21755,curation_candidate,22411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21756,curation_candidate,22459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21757,curation_candidate,22555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21758,curation_candidate,22697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21759,curation_candidate,22726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21760,curation_candidate,22852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21761,curation_candidate,22871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21762,curation_candidate,23020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21763,curation_candidate,23176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21764,curation_candidate,23193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21765,curation_candidate,23207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21766,curation_candidate,23254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21767,curation_candidate,23259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21768,curation_candidate,23350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21769,curation_candidate,23385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21770,curation_candidate,23451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21771,curation_candidate,23664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21772,curation_candidate,23665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21773,curation_candidate,23720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21774,curation_candidate,23733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21775,curation_candidate,23803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21776,curation_candidate,23807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21777,curation_candidate,24183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21778,curation_candidate,24297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21779,curation_candidate,24480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21780,curation_candidate,24602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21781,curation_candidate,24792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21782,curation_candidate,24963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21783,curation_candidate,24988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21784,curation_candidate,25034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21785,curation_candidate,25129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21786,curation_candidate,25139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21787,curation_candidate,25155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21788,curation_candidate,25301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21789,curation_candidate,25332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21790,curation_candidate,25343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21791,curation_candidate,25369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21792,curation_candidate,25387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21793,curation_candidate,25655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21794,curation_candidate,25656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21795,curation_candidate,25918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21796,curation_candidate,25959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21797,curation_candidate,25964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21798,curation_candidate,25996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21799,curation_candidate,26018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21800,curation_candidate,26084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21801,curation_candidate,26165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21802,curation_candidate,26170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21803,curation_candidate,26183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21804,curation_candidate,26195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21805,curation_candidate,26351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21806,curation_candidate,26444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21807,curation_candidate,26870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21808,curation_candidate,26953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21809,curation_candidate,27057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21810,curation_candidate,27177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21811,curation_candidate,27255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21812,curation_candidate,27286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21813,curation_candidate,27451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
21814,curation_candidate,27687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21815,curation_candidate,27852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21816,curation_candidate,27925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21817,curation_candidate,27931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21818,curation_candidate,28100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21819,curation_candidate,28119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21820,curation_candidate,28185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21821,curation_candidate,28209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21822,curation_candidate,28249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21823,curation_candidate,28258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21824,curation_candidate,28286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21825,curation_candidate,28371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21826,curation_candidate,28419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21827,curation_candidate,28450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21828,curation_candidate,28456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21829,curation_candidate,28492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
21830,curation_candidate,28505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21831,curation_candidate,28532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21832,curation_candidate,28646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21833,curation_candidate,28768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21834,curation_candidate,28782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21835,curation_candidate,28860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21836,curation_candidate,28902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21837,curation_candidate,28922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21838,curation_candidate,28930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21839,curation_candidate,29003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21840,curation_candidate,29007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21841,curation_candidate,29015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21842,curation_candidate,29027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21843,curation_candidate,29069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21844,curation_candidate,29078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21845,curation_candidate,29166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21846,curation_candidate,29265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21847,curation_candidate,29271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21848,curation_candidate,29293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21849,curation_candidate,29309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21850,curation_candidate,29389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21851,curation_candidate,29410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21852,curation_candidate,29480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21853,curation_candidate,29529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21854,curation_candidate,29532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21855,curation_candidate,29655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21856,curation_candidate,30407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21857,curation_candidate,30606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21858,curation_candidate,30868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21859,curation_candidate,30896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21860,curation_candidate,31043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21861,curation_candidate,31148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21862,curation_candidate,31322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21863,curation_candidate,32049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21864,curation_candidate,32115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21865,curation_candidate,32699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21866,curation_candidate,33009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21867,curation_candidate,33843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21868,curation_candidate,34041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21869,curation_candidate,34124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21870,curation_candidate,34495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21871,curation_candidate,34685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21872,curation_candidate,35159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21873,curation_candidate,35772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21874,curation_candidate,36102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21875,curation_candidate,36786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21876,curation_candidate,16326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21877,curation_candidate,16446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21878,curation_candidate,16562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21879,curation_candidate,16859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21880,curation_candidate,16911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21881,curation_candidate,17042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21882,curation_candidate,17102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21883,curation_candidate,17196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21884,curation_candidate,17283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21885,curation_candidate,17290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21886,curation_candidate,17744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21887,curation_candidate,17818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21888,curation_candidate,17841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21889,curation_candidate,17960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21890,curation_candidate,18061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21891,curation_candidate,18171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21892,curation_candidate,18194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21893,curation_candidate,18318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21894,curation_candidate,18461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21895,curation_candidate,18645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21896,curation_candidate,18661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21897,curation_candidate,18749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21898,curation_candidate,18852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21899,curation_candidate,18872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21900,curation_candidate,18902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21901,curation_candidate,18931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21902,curation_candidate,18973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21903,curation_candidate,19021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21904,curation_candidate,19220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21905,curation_candidate,19222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21906,curation_candidate,19327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21907,curation_candidate,19383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21908,curation_candidate,19512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21909,curation_candidate,19579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21910,curation_candidate,19641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21911,curation_candidate,19684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21912,curation_candidate,19729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21913,curation_candidate,19772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21914,curation_candidate,19916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21915,curation_candidate,20141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21916,curation_candidate,20182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21917,curation_candidate,20284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21918,curation_candidate,20296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21919,curation_candidate,20386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21920,curation_candidate,20395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21921,curation_candidate,20622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21922,curation_candidate,20744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21923,curation_candidate,20826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21924,curation_candidate,20890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21925,curation_candidate,20914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21926,curation_candidate,21123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21927,curation_candidate,21184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21928,curation_candidate,21365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21929,curation_candidate,21385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21930,curation_candidate,21516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21931,curation_candidate,21601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21932,curation_candidate,21706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21933,curation_candidate,21751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
21934,curation_candidate,21772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
21935,curation_candidate,21969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21936,curation_candidate,22019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21937,curation_candidate,22051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21938,curation_candidate,22202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21939,curation_candidate,22240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21940,curation_candidate,22301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21941,curation_candidate,22394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21942,curation_candidate,22469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21943,curation_candidate,22518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21944,curation_candidate,22659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21945,curation_candidate,22707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21946,curation_candidate,22768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21947,curation_candidate,22878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21948,curation_candidate,22903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21949,curation_candidate,22925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21950,curation_candidate,22953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21951,curation_candidate,22956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21952,curation_candidate,22962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21953,curation_candidate,23066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21954,curation_candidate,23069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21955,curation_candidate,23162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21956,curation_candidate,23170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21957,curation_candidate,23443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21958,curation_candidate,23477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21959,curation_candidate,23515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21960,curation_candidate,23730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21961,curation_candidate,23771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21962,curation_candidate,23924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21963,curation_candidate,24008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21964,curation_candidate,24199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21965,curation_candidate,24340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21966,curation_candidate,24405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21967,curation_candidate,24537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21968,curation_candidate,24660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21969,curation_candidate,24670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21970,curation_candidate,24755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21971,curation_candidate,24879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21972,curation_candidate,24904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21973,curation_candidate,24940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21974,curation_candidate,24958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21975,curation_candidate,25003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21976,curation_candidate,25060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
21977,curation_candidate,25187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21978,curation_candidate,25518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21979,curation_candidate,25670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
21980,curation_candidate,25831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
21981,curation_candidate,25955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
21982,curation_candidate,26094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21983,curation_candidate,26124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21984,curation_candidate,26148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21985,curation_candidate,26163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21986,curation_candidate,26212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21987,curation_candidate,26252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21988,curation_candidate,26254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21989,curation_candidate,26270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21990,curation_candidate,26296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21991,curation_candidate,26331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21992,curation_candidate,26347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21993,curation_candidate,26389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21994,curation_candidate,26506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21995,curation_candidate,26697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21996,curation_candidate,26783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21997,curation_candidate,26879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
21998,curation_candidate,26978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
21999,curation_candidate,26983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22000,curation_candidate,27196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22001,curation_candidate,27372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22002,curation_candidate,27446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22003,curation_candidate,27487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22004,curation_candidate,27501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22005,curation_candidate,27605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22006,curation_candidate,27629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22007,curation_candidate,27650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22008,curation_candidate,27761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22009,curation_candidate,27770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22010,curation_candidate,27805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22011,curation_candidate,27808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22012,curation_candidate,27881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22013,curation_candidate,27935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22014,curation_candidate,27985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22015,curation_candidate,28069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22016,curation_candidate,28084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22017,curation_candidate,28105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22018,curation_candidate,28109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22019,curation_candidate,28330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22020,curation_candidate,28355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22021,curation_candidate,28393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22022,curation_candidate,28434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22023,curation_candidate,28465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22024,curation_candidate,28539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22025,curation_candidate,28548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22026,curation_candidate,28639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22027,curation_candidate,28723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22028,curation_candidate,28881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22029,curation_candidate,28907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22030,curation_candidate,28940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22031,curation_candidate,28959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22032,curation_candidate,28971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22033,curation_candidate,28983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22034,curation_candidate,29032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22035,curation_candidate,29038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22036,curation_candidate,29104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22037,curation_candidate,29201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22038,curation_candidate,29202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22039,curation_candidate,29223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22040,curation_candidate,29229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22041,curation_candidate,29277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22042,curation_candidate,29308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22043,curation_candidate,29400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22044,curation_candidate,29438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22045,curation_candidate,29615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22046,curation_candidate,29721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22047,curation_candidate,29791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22048,curation_candidate,29808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22049,curation_candidate,30272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22050,curation_candidate,30277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22051,curation_candidate,30336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22052,curation_candidate,30412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22053,curation_candidate,30579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22054,curation_candidate,30786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22055,curation_candidate,30938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22056,curation_candidate,31408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22057,curation_candidate,31718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22058,curation_candidate,31906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22059,curation_candidate,32200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22060,curation_candidate,32290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22061,curation_candidate,33633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22062,curation_candidate,33809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22063,curation_candidate,33907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22064,curation_candidate,34822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22065,curation_candidate,36526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22066,curation_candidate,36563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22067,curation_candidate,36631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22068,curation_candidate,36813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
22069,curation_candidate,36817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22070,curation_candidate,36853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
22071,curation_candidate,36994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22072,curation_candidate,37060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22073,curation_candidate,38286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22074,curation_candidate,16343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22075,curation_candidate,16348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22076,curation_candidate,16360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22077,curation_candidate,16367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22078,curation_candidate,16378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22079,curation_candidate,16582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22080,curation_candidate,16603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22081,curation_candidate,17157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22082,curation_candidate,17215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22083,curation_candidate,17802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22084,curation_candidate,17809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22085,curation_candidate,17832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22086,curation_candidate,17885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22087,curation_candidate,17904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22088,curation_candidate,17941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22089,curation_candidate,18035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22090,curation_candidate,18107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22091,curation_candidate,18120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22092,curation_candidate,18147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22093,curation_candidate,18212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
22094,curation_candidate,18427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22095,curation_candidate,18428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22096,curation_candidate,18589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22097,curation_candidate,18667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22098,curation_candidate,18836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22099,curation_candidate,18867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22100,curation_candidate,18939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22101,curation_candidate,18970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22102,curation_candidate,19067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22103,curation_candidate,19252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22104,curation_candidate,19375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22105,curation_candidate,19387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22106,curation_candidate,19621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22107,curation_candidate,19764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22108,curation_candidate,19873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22109,curation_candidate,19897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22110,curation_candidate,20006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22111,curation_candidate,20116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22112,curation_candidate,20120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22113,curation_candidate,20193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22114,curation_candidate,20235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22115,curation_candidate,20247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22116,curation_candidate,20448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22117,curation_candidate,20458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22118,curation_candidate,20551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22119,curation_candidate,20560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22120,curation_candidate,20561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22121,curation_candidate,20574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22122,curation_candidate,20664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22123,curation_candidate,20691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22124,curation_candidate,20711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22125,curation_candidate,20715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22126,curation_candidate,20833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22127,curation_candidate,20998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22128,curation_candidate,21121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22129,curation_candidate,21197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22130,curation_candidate,21260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22131,curation_candidate,21321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22132,curation_candidate,21400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22133,curation_candidate,21472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22134,curation_candidate,21500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22135,curation_candidate,21689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22136,curation_candidate,21704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22137,curation_candidate,21759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22138,curation_candidate,21813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22139,curation_candidate,21880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22140,curation_candidate,21924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22141,curation_candidate,21937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22142,curation_candidate,22035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22143,curation_candidate,22057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22144,curation_candidate,22072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22145,curation_candidate,22078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22146,curation_candidate,22114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22147,curation_candidate,22254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22148,curation_candidate,22349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22149,curation_candidate,22463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22150,curation_candidate,22510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22151,curation_candidate,22548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22152,curation_candidate,22566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22153,curation_candidate,22720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22154,curation_candidate,22813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22155,curation_candidate,22845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22156,curation_candidate,22915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22157,curation_candidate,22973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22158,curation_candidate,23060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22159,curation_candidate,23114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22160,curation_candidate,23409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22161,curation_candidate,23460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22162,curation_candidate,23658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22163,curation_candidate,23688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22164,curation_candidate,23778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22165,curation_candidate,23952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22166,curation_candidate,23977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22167,curation_candidate,23991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22168,curation_candidate,24009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22169,curation_candidate,24035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22170,curation_candidate,24096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22171,curation_candidate,24136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22172,curation_candidate,24280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22173,curation_candidate,24457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22174,curation_candidate,24479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22175,curation_candidate,24504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22176,curation_candidate,24522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22177,curation_candidate,24527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22178,curation_candidate,24538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22179,curation_candidate,24573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22180,curation_candidate,24594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22181,curation_candidate,24683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22182,curation_candidate,24711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22183,curation_candidate,24849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22184,curation_candidate,24944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22185,curation_candidate,24967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22186,curation_candidate,24983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22187,curation_candidate,25010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22188,curation_candidate,25117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22189,curation_candidate,25195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22190,curation_candidate,25232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22191,curation_candidate,25243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22192,curation_candidate,25250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22193,curation_candidate,25268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22194,curation_candidate,25377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22195,curation_candidate,25547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22196,curation_candidate,25619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22197,curation_candidate,25620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22198,curation_candidate,25634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22199,curation_candidate,26016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22200,curation_candidate,26101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22201,curation_candidate,26162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22202,curation_candidate,26311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22203,curation_candidate,26424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22204,curation_candidate,26491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22205,curation_candidate,26556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22206,curation_candidate,26634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22207,curation_candidate,26688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22208,curation_candidate,26691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22209,curation_candidate,26723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22210,curation_candidate,26729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22211,curation_candidate,26816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22212,curation_candidate,26933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22213,curation_candidate,27043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22214,curation_candidate,27106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22215,curation_candidate,27175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22216,curation_candidate,27279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22217,curation_candidate,27296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22218,curation_candidate,27351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22219,curation_candidate,27439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22220,curation_candidate,27485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22221,curation_candidate,27531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22222,curation_candidate,27594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22223,curation_candidate,27679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22224,curation_candidate,27746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22225,curation_candidate,27753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22226,curation_candidate,27832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22227,curation_candidate,27855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22228,curation_candidate,27879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22229,curation_candidate,27951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22230,curation_candidate,28120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22231,curation_candidate,28126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22232,curation_candidate,28140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22233,curation_candidate,28204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22234,curation_candidate,28275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22235,curation_candidate,28289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22236,curation_candidate,28416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22237,curation_candidate,28433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22238,curation_candidate,28701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22239,curation_candidate,28871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22240,curation_candidate,28878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22241,curation_candidate,28939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22242,curation_candidate,29041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22243,curation_candidate,29049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22244,curation_candidate,29081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22245,curation_candidate,29110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22246,curation_candidate,29180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22247,curation_candidate,29228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22248,curation_candidate,29266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22249,curation_candidate,29269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22250,curation_candidate,29323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22251,curation_candidate,29439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22252,curation_candidate,29520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22253,curation_candidate,29545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22254,curation_candidate,29546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22255,curation_candidate,29745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22256,curation_candidate,29766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22257,curation_candidate,29847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22258,curation_candidate,30170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22259,curation_candidate,30322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22260,curation_candidate,30462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22261,curation_candidate,30794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22262,curation_candidate,30827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22263,curation_candidate,30886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22264,curation_candidate,30929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22265,curation_candidate,31117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22266,curation_candidate,31241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22267,curation_candidate,31280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22268,curation_candidate,31813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22269,curation_candidate,32075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22270,curation_candidate,32777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22271,curation_candidate,33023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22272,curation_candidate,33757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22273,curation_candidate,33831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22274,curation_candidate,33863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22275,curation_candidate,34254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22276,curation_candidate,34279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22277,curation_candidate,34373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22278,curation_candidate,34526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22279,curation_candidate,34838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22280,curation_candidate,35012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22281,curation_candidate,35072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22282,curation_candidate,35076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22283,curation_candidate,35110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22284,curation_candidate,35212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22285,curation_candidate,35451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22286,curation_candidate,35463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22287,curation_candidate,35594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22288,curation_candidate,35628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22289,curation_candidate,35636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22290,curation_candidate,35647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22291,curation_candidate,35913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22292,curation_candidate,36053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22293,curation_candidate,36179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
22294,curation_candidate,36269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22295,curation_candidate,36436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22296,curation_candidate,36725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22297,curation_candidate,36728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22298,curation_candidate,36834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22299,curation_candidate,36873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22300,curation_candidate,36880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22301,curation_candidate,36909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
22302,curation_candidate,36927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22303,curation_candidate,36928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22304,curation_candidate,37519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22305,curation_candidate,37538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22306,curation_candidate,37640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22307,curation_candidate,37668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22308,curation_candidate,37809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22309,curation_candidate,37820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22310,curation_candidate,16386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22311,curation_candidate,16496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22312,curation_candidate,16542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22313,curation_candidate,16737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22314,curation_candidate,16896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22315,curation_candidate,17068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22316,curation_candidate,17140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
22317,curation_candidate,17150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22318,curation_candidate,17330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22319,curation_candidate,17354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22320,curation_candidate,17584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22321,curation_candidate,17642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22322,curation_candidate,17794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22323,curation_candidate,17930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22324,curation_candidate,17938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22325,curation_candidate,17981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22326,curation_candidate,18036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22327,curation_candidate,18041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22328,curation_candidate,18073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22329,curation_candidate,18082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22330,curation_candidate,18123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22331,curation_candidate,18124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22332,curation_candidate,18182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22333,curation_candidate,18188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22334,curation_candidate,18200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22335,curation_candidate,18237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22336,curation_candidate,18283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22337,curation_candidate,18367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22338,curation_candidate,18442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22339,curation_candidate,18545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22340,curation_candidate,18553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22341,curation_candidate,18775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22342,curation_candidate,18843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22343,curation_candidate,18901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22344,curation_candidate,19041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22345,curation_candidate,19183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22346,curation_candidate,19242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22347,curation_candidate,19312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22348,curation_candidate,19318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22349,curation_candidate,19351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
22350,curation_candidate,19453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22351,curation_candidate,19500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22352,curation_candidate,19539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22353,curation_candidate,19573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22354,curation_candidate,19612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22355,curation_candidate,19634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22356,curation_candidate,19637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22357,curation_candidate,19751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22358,curation_candidate,19832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22359,curation_candidate,19884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22360,curation_candidate,20000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22361,curation_candidate,20075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22362,curation_candidate,20098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22363,curation_candidate,20167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22364,curation_candidate,20219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22365,curation_candidate,20392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22366,curation_candidate,20556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22367,curation_candidate,20566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22368,curation_candidate,20604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22369,curation_candidate,20651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22370,curation_candidate,20669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22371,curation_candidate,20675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22372,curation_candidate,20817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22373,curation_candidate,20920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22374,curation_candidate,20934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22375,curation_candidate,20988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22376,curation_candidate,21106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22377,curation_candidate,21171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22378,curation_candidate,21202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22379,curation_candidate,21241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22380,curation_candidate,21294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22381,curation_candidate,21348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22382,curation_candidate,21425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22383,curation_candidate,21434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22384,curation_candidate,21467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22385,curation_candidate,21480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22386,curation_candidate,21481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22387,curation_candidate,21488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22388,curation_candidate,21635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22389,curation_candidate,21649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22390,curation_candidate,21653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22391,curation_candidate,21695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22392,curation_candidate,21727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22393,curation_candidate,21731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22394,curation_candidate,21761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22395,curation_candidate,21842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22396,curation_candidate,21867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22397,curation_candidate,22043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22398,curation_candidate,22104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22399,curation_candidate,22116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22400,curation_candidate,22258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22401,curation_candidate,22268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22402,curation_candidate,22300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22403,curation_candidate,22312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22404,curation_candidate,22421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22405,curation_candidate,22458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22406,curation_candidate,22492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22407,curation_candidate,22734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22408,curation_candidate,22765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22409,curation_candidate,22790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22410,curation_candidate,22832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22411,curation_candidate,22835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22412,curation_candidate,23037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22413,curation_candidate,23045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22414,curation_candidate,23129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22415,curation_candidate,23184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22416,curation_candidate,23309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22417,curation_candidate,23345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22418,curation_candidate,23381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22419,curation_candidate,23402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22420,curation_candidate,23410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22421,curation_candidate,23483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22422,curation_candidate,23508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22423,curation_candidate,23513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22424,curation_candidate,23630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22425,curation_candidate,23715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22426,curation_candidate,23798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22427,curation_candidate,23823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22428,curation_candidate,23835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22429,curation_candidate,23868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22430,curation_candidate,23875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22431,curation_candidate,24003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22432,curation_candidate,24065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22433,curation_candidate,24135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22434,curation_candidate,24209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22435,curation_candidate,24276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22436,curation_candidate,24356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22437,curation_candidate,24524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22438,curation_candidate,24582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22439,curation_candidate,24593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22440,curation_candidate,24676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22441,curation_candidate,24680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22442,curation_candidate,24682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22443,curation_candidate,24717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22444,curation_candidate,24735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22445,curation_candidate,24750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22446,curation_candidate,24763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22447,curation_candidate,24856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22448,curation_candidate,24905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22449,curation_candidate,24972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22450,curation_candidate,24989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22451,curation_candidate,25012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22452,curation_candidate,25099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22453,curation_candidate,25140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22454,curation_candidate,25146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22455,curation_candidate,25175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22456,curation_candidate,25177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22457,curation_candidate,25182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22458,curation_candidate,25224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22459,curation_candidate,25239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22460,curation_candidate,25258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22461,curation_candidate,25434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22462,curation_candidate,25516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22463,curation_candidate,25537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22464,curation_candidate,25557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22465,curation_candidate,25582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22466,curation_candidate,25592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22467,curation_candidate,25593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22468,curation_candidate,25681,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22469,curation_candidate,25746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22470,curation_candidate,25816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22471,curation_candidate,25823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22472,curation_candidate,26041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22473,curation_candidate,26075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22474,curation_candidate,26140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22475,curation_candidate,26166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22476,curation_candidate,26327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22477,curation_candidate,26362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22478,curation_candidate,26411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22479,curation_candidate,26467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22480,curation_candidate,26514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22481,curation_candidate,26553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22482,curation_candidate,26608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22483,curation_candidate,26615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22484,curation_candidate,26629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22485,curation_candidate,26683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22486,curation_candidate,26800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22487,curation_candidate,26960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22488,curation_candidate,27002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22489,curation_candidate,27073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22490,curation_candidate,27094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22491,curation_candidate,27108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22492,curation_candidate,27119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22493,curation_candidate,27171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22494,curation_candidate,27307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22495,curation_candidate,27424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22496,curation_candidate,27436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22497,curation_candidate,27443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22498,curation_candidate,27496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22499,curation_candidate,27519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22500,curation_candidate,27562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22501,curation_candidate,27604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22502,curation_candidate,27608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22503,curation_candidate,27611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22504,curation_candidate,27630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22505,curation_candidate,27648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22506,curation_candidate,27656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22507,curation_candidate,27759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22508,curation_candidate,27769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22509,curation_candidate,27803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22510,curation_candidate,27959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22511,curation_candidate,27966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22512,curation_candidate,27967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22513,curation_candidate,28033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22514,curation_candidate,28034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22515,curation_candidate,28053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22516,curation_candidate,28080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22517,curation_candidate,28134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22518,curation_candidate,28188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22519,curation_candidate,28234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22520,curation_candidate,28270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22521,curation_candidate,28316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22522,curation_candidate,28347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22523,curation_candidate,28540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22524,curation_candidate,28550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22525,curation_candidate,28624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22526,curation_candidate,28661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22527,curation_candidate,28665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
22528,curation_candidate,28676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22529,curation_candidate,28772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22530,curation_candidate,28777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22531,curation_candidate,28795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22532,curation_candidate,28808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22533,curation_candidate,28858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22534,curation_candidate,28953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22535,curation_candidate,28997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22536,curation_candidate,29084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22537,curation_candidate,29136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22538,curation_candidate,29143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22539,curation_candidate,29168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22540,curation_candidate,29195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22541,curation_candidate,29234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22542,curation_candidate,29267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22543,curation_candidate,29282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22544,curation_candidate,29289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22545,curation_candidate,29305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22546,curation_candidate,29330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22547,curation_candidate,29373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22548,curation_candidate,29380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22549,curation_candidate,29451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22550,curation_candidate,29500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22551,curation_candidate,29738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22552,curation_candidate,29809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22553,curation_candidate,30012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22554,curation_candidate,30472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22555,curation_candidate,30613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22556,curation_candidate,30654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22557,curation_candidate,30974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22558,curation_candidate,31147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22559,curation_candidate,31358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22560,curation_candidate,31629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22561,curation_candidate,31901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22562,curation_candidate,31962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22563,curation_candidate,31972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22564,curation_candidate,32116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22565,curation_candidate,32174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
22566,curation_candidate,32205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22567,curation_candidate,32317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22568,curation_candidate,32427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22569,curation_candidate,32513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22570,curation_candidate,32550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22571,curation_candidate,32730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22572,curation_candidate,32952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22573,curation_candidate,33066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22574,curation_candidate,33320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22575,curation_candidate,33712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22576,curation_candidate,33932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22577,curation_candidate,34099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22578,curation_candidate,34232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22579,curation_candidate,34237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22580,curation_candidate,34274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22581,curation_candidate,34303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22582,curation_candidate,34485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22583,curation_candidate,34525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22584,curation_candidate,34596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22585,curation_candidate,34953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22586,curation_candidate,35310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22587,curation_candidate,35370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22588,curation_candidate,35376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22589,curation_candidate,35716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22590,curation_candidate,35722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22591,curation_candidate,35748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22592,curation_candidate,36024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22593,curation_candidate,36372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22594,curation_candidate,36397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22595,curation_candidate,36425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22596,curation_candidate,36458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22597,curation_candidate,36510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22598,curation_candidate,36533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22599,curation_candidate,36551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22600,curation_candidate,36674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22601,curation_candidate,36797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22602,curation_candidate,36811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22603,curation_candidate,36879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22604,curation_candidate,36912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22605,curation_candidate,36969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22606,curation_candidate,37089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22607,curation_candidate,37163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22608,curation_candidate,37174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22609,curation_candidate,37198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22610,curation_candidate,37344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22611,curation_candidate,37515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22612,curation_candidate,37666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22613,curation_candidate,37695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22614,curation_candidate,37700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22615,curation_candidate,37884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22616,curation_candidate,38139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22617,curation_candidate,38205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22618,curation_candidate,38249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22619,curation_candidate,16327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22620,curation_candidate,16355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22621,curation_candidate,16514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22622,curation_candidate,16571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22623,curation_candidate,16648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22624,curation_candidate,16649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22625,curation_candidate,16653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22626,curation_candidate,16673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22627,curation_candidate,16733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22628,curation_candidate,16797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22629,curation_candidate,16798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22630,curation_candidate,16822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22631,curation_candidate,16876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22632,curation_candidate,16971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22633,curation_candidate,16986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22634,curation_candidate,17021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22635,curation_candidate,17106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22636,curation_candidate,17318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22637,curation_candidate,17533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22638,curation_candidate,17702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22639,curation_candidate,17724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22640,curation_candidate,17758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22641,curation_candidate,17760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22642,curation_candidate,17843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22643,curation_candidate,17867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22644,curation_candidate,17884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22645,curation_candidate,17910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22646,curation_candidate,18293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22647,curation_candidate,18319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22648,curation_candidate,18387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22649,curation_candidate,18413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22650,curation_candidate,18580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22651,curation_candidate,18668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22652,curation_candidate,18680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22653,curation_candidate,18704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22654,curation_candidate,18726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22655,curation_candidate,18797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22656,curation_candidate,18851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22657,curation_candidate,18871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22658,curation_candidate,18873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22659,curation_candidate,18924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22660,curation_candidate,18963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22661,curation_candidate,19094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22662,curation_candidate,19141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22663,curation_candidate,19214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22664,curation_candidate,19246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22665,curation_candidate,19248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22666,curation_candidate,19274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22667,curation_candidate,19297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22668,curation_candidate,19363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22669,curation_candidate,19415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22670,curation_candidate,19449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22671,curation_candidate,19828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22672,curation_candidate,19911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22673,curation_candidate,19957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22674,curation_candidate,20021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22675,curation_candidate,20130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22676,curation_candidate,20151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22677,curation_candidate,20278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22678,curation_candidate,20320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22679,curation_candidate,20367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22680,curation_candidate,20440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22681,curation_candidate,20467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22682,curation_candidate,20481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22683,curation_candidate,20504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22684,curation_candidate,20521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22685,curation_candidate,20585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22686,curation_candidate,20667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22687,curation_candidate,20710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22688,curation_candidate,20714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22689,curation_candidate,20792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22690,curation_candidate,20845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22691,curation_candidate,20863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22692,curation_candidate,20884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22693,curation_candidate,20894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22694,curation_candidate,21018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22695,curation_candidate,21064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22696,curation_candidate,21280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22697,curation_candidate,21364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
22698,curation_candidate,21417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22699,curation_candidate,21439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22700,curation_candidate,21535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22701,curation_candidate,21573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22702,curation_candidate,21574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22703,curation_candidate,21658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22704,curation_candidate,21696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22705,curation_candidate,21762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22706,curation_candidate,21815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22707,curation_candidate,21866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22708,curation_candidate,21871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22709,curation_candidate,21975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22710,curation_candidate,22079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22711,curation_candidate,22096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22712,curation_candidate,22127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22713,curation_candidate,22167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22714,curation_candidate,22168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22715,curation_candidate,22261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22716,curation_candidate,22266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22717,curation_candidate,22406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22718,curation_candidate,22410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22719,curation_candidate,22426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22720,curation_candidate,22567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22721,curation_candidate,22663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22722,curation_candidate,22693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22723,curation_candidate,22706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22724,curation_candidate,22723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22725,curation_candidate,22746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22726,curation_candidate,22769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22727,curation_candidate,22819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22728,curation_candidate,22876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22729,curation_candidate,23025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22730,curation_candidate,23143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22731,curation_candidate,23154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22732,curation_candidate,23227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22733,curation_candidate,23243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22734,curation_candidate,23279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22735,curation_candidate,23355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22736,curation_candidate,23435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22737,curation_candidate,23505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22738,curation_candidate,23677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22739,curation_candidate,23783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22740,curation_candidate,23826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22741,curation_candidate,23900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22742,curation_candidate,23982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22743,curation_candidate,24123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22744,curation_candidate,24218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22745,curation_candidate,24320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22746,curation_candidate,24376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22747,curation_candidate,24383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22748,curation_candidate,24525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22749,curation_candidate,24548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22750,curation_candidate,24601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22751,curation_candidate,24623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22752,curation_candidate,24635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22753,curation_candidate,24737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22754,curation_candidate,24775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22755,curation_candidate,24804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22756,curation_candidate,24873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22757,curation_candidate,24911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22758,curation_candidate,24935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22759,curation_candidate,25002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22760,curation_candidate,25091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22761,curation_candidate,25130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22762,curation_candidate,25220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22763,curation_candidate,25257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22764,curation_candidate,25290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22765,curation_candidate,25304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22766,curation_candidate,25311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22767,curation_candidate,25320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22768,curation_candidate,25467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22769,curation_candidate,25818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22770,curation_candidate,25902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22771,curation_candidate,25988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22772,curation_candidate,26020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22773,curation_candidate,26106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22774,curation_candidate,26240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22775,curation_candidate,26281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22776,curation_candidate,26325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22777,curation_candidate,26334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22778,curation_candidate,26337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22779,curation_candidate,26338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22780,curation_candidate,26370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22781,curation_candidate,26380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22782,curation_candidate,26381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22783,curation_candidate,26405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22784,curation_candidate,26460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22785,curation_candidate,26495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22786,curation_candidate,26526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22787,curation_candidate,26544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22788,curation_candidate,26564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22789,curation_candidate,26625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22790,curation_candidate,26644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22791,curation_candidate,26716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22792,curation_candidate,26724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22793,curation_candidate,26736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22794,curation_candidate,26785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22795,curation_candidate,26824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22796,curation_candidate,26833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22797,curation_candidate,26976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22798,curation_candidate,27035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22799,curation_candidate,27065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22800,curation_candidate,27089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22801,curation_candidate,27107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22802,curation_candidate,27123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22803,curation_candidate,27185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22804,curation_candidate,27191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22805,curation_candidate,27195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22806,curation_candidate,27229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22807,curation_candidate,27258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22808,curation_candidate,27266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22809,curation_candidate,27287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22810,curation_candidate,27299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22811,curation_candidate,27313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22812,curation_candidate,27338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22813,curation_candidate,27453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22814,curation_candidate,27488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22815,curation_candidate,27577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22816,curation_candidate,27614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22817,curation_candidate,27621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22818,curation_candidate,27651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22819,curation_candidate,27675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22820,curation_candidate,27680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22821,curation_candidate,27692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22822,curation_candidate,27783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22823,curation_candidate,27894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22824,curation_candidate,27900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22825,curation_candidate,27904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22826,curation_candidate,27909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22827,curation_candidate,27941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22828,curation_candidate,27943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22829,curation_candidate,27945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22830,curation_candidate,27954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22831,curation_candidate,27983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22832,curation_candidate,28020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22833,curation_candidate,28027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22834,curation_candidate,28031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22835,curation_candidate,28156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22836,curation_candidate,28254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22837,curation_candidate,28279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22838,curation_candidate,28293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22839,curation_candidate,28322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22840,curation_candidate,28345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22841,curation_candidate,28370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22842,curation_candidate,28396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22843,curation_candidate,28399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22844,curation_candidate,28407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22845,curation_candidate,28479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22846,curation_candidate,28658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22847,curation_candidate,28752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22848,curation_candidate,28774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22849,curation_candidate,28837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22850,curation_candidate,28876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22851,curation_candidate,28885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22852,curation_candidate,28950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22853,curation_candidate,29098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22854,curation_candidate,29239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22855,curation_candidate,29272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22856,curation_candidate,29287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22857,curation_candidate,29386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22858,curation_candidate,29412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22859,curation_candidate,29486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22860,curation_candidate,29559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22861,curation_candidate,29675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22862,curation_candidate,29764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22863,curation_candidate,29925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22864,curation_candidate,29994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22865,curation_candidate,30024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22866,curation_candidate,30513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22867,curation_candidate,30616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
22868,curation_candidate,30665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22869,curation_candidate,30783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22870,curation_candidate,30817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22871,curation_candidate,31099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22872,curation_candidate,31111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22873,curation_candidate,31223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22874,curation_candidate,31426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22875,curation_candidate,31542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22876,curation_candidate,31549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22877,curation_candidate,31599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22878,curation_candidate,32060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22879,curation_candidate,32067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22880,curation_candidate,32120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22881,curation_candidate,32184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22882,curation_candidate,32240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22883,curation_candidate,32279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22884,curation_candidate,32503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22885,curation_candidate,32522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22886,curation_candidate,32659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
22887,curation_candidate,32808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22888,curation_candidate,33378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22889,curation_candidate,33775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22890,curation_candidate,33791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22891,curation_candidate,34155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22892,curation_candidate,34415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22893,curation_candidate,34610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22894,curation_candidate,34611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22895,curation_candidate,34614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22896,curation_candidate,34615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22897,curation_candidate,34760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22898,curation_candidate,34783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22899,curation_candidate,34835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22900,curation_candidate,34843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22901,curation_candidate,34856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22902,curation_candidate,35027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22903,curation_candidate,35342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
22904,curation_candidate,35440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22905,curation_candidate,35459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22906,curation_candidate,35462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22907,curation_candidate,35560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22908,curation_candidate,35744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22909,curation_candidate,35823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22910,curation_candidate,35870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22911,curation_candidate,35881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22912,curation_candidate,35968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22913,curation_candidate,36100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22914,curation_candidate,36128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22915,curation_candidate,36184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22916,curation_candidate,36315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22917,curation_candidate,36321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22918,curation_candidate,36391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22919,curation_candidate,36428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22920,curation_candidate,36435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22921,curation_candidate,36545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22922,curation_candidate,36555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22923,curation_candidate,36573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22924,curation_candidate,36606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22925,curation_candidate,36652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22926,curation_candidate,36732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22927,curation_candidate,36768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22928,curation_candidate,36809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22929,curation_candidate,36886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22930,curation_candidate,36888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22931,curation_candidate,36939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22932,curation_candidate,36954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22933,curation_candidate,37054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22934,curation_candidate,37123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22935,curation_candidate,37165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22936,curation_candidate,37242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22937,curation_candidate,37285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22938,curation_candidate,37387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22939,curation_candidate,37461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22940,curation_candidate,37464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22941,curation_candidate,37673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22942,curation_candidate,37696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22943,curation_candidate,37709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22944,curation_candidate,37990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22945,curation_candidate,38108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22946,curation_candidate,38183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22947,curation_candidate,38306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22948,curation_candidate,16332,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22949,curation_candidate,16487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22950,curation_candidate,16521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22951,curation_candidate,16766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22952,curation_candidate,16958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22953,curation_candidate,16985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22954,curation_candidate,17092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22955,curation_candidate,17143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22956,curation_candidate,17370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22957,curation_candidate,17394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22958,curation_candidate,17419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22959,curation_candidate,17518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22960,curation_candidate,17594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22961,curation_candidate,17629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22962,curation_candidate,17796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22963,curation_candidate,17882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22964,curation_candidate,17923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22965,curation_candidate,17993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22966,curation_candidate,17996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22967,curation_candidate,18038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22968,curation_candidate,18096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22969,curation_candidate,18203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22970,curation_candidate,18310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22971,curation_candidate,18371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22972,curation_candidate,18423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22973,curation_candidate,18597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22974,curation_candidate,18616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
22975,curation_candidate,18620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22976,curation_candidate,18910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22977,curation_candidate,18965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22978,curation_candidate,19023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22979,curation_candidate,19027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22980,curation_candidate,19057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22981,curation_candidate,19074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22982,curation_candidate,19098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22983,curation_candidate,19147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22984,curation_candidate,19177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22985,curation_candidate,19201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
22986,curation_candidate,19215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22987,curation_candidate,19254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22988,curation_candidate,19260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22989,curation_candidate,19284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22990,curation_candidate,19308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22991,curation_candidate,19314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22992,curation_candidate,19362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22993,curation_candidate,19374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22994,curation_candidate,19444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22995,curation_candidate,19505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22996,curation_candidate,19646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22997,curation_candidate,19647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
22998,curation_candidate,19677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
22999,curation_candidate,19694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23000,curation_candidate,19770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23001,curation_candidate,19781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
23002,curation_candidate,19801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23003,curation_candidate,19920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23004,curation_candidate,19939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23005,curation_candidate,19999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23006,curation_candidate,20019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23007,curation_candidate,20058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23008,curation_candidate,20076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23009,curation_candidate,20081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23010,curation_candidate,20083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23011,curation_candidate,20131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23012,curation_candidate,20225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23013,curation_candidate,20346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23014,curation_candidate,20370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23015,curation_candidate,20433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23016,curation_candidate,20496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23017,curation_candidate,20645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23018,curation_candidate,20657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23019,curation_candidate,20728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23020,curation_candidate,20731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23021,curation_candidate,20789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23022,curation_candidate,20793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23023,curation_candidate,20918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23024,curation_candidate,21091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23025,curation_candidate,21157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23026,curation_candidate,21167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23027,curation_candidate,21201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23028,curation_candidate,21234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23029,curation_candidate,21239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23030,curation_candidate,21327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23031,curation_candidate,21357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23032,curation_candidate,21391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23033,curation_candidate,21421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23034,curation_candidate,21430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23035,curation_candidate,21498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23036,curation_candidate,21521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23037,curation_candidate,21549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23038,curation_candidate,21590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23039,curation_candidate,21619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23040,curation_candidate,21657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23041,curation_candidate,21670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23042,curation_candidate,21678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23043,curation_candidate,21694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23044,curation_candidate,21778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23045,curation_candidate,21832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23046,curation_candidate,22015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23047,curation_candidate,22063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23048,curation_candidate,22075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23049,curation_candidate,22142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23050,curation_candidate,22208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23051,curation_candidate,22243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23052,curation_candidate,22252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23053,curation_candidate,22331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23054,curation_candidate,22404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23055,curation_candidate,22439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23056,curation_candidate,22502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23057,curation_candidate,22558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23058,curation_candidate,22601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23059,curation_candidate,22651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23060,curation_candidate,22652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23061,curation_candidate,22674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23062,curation_candidate,22694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23063,curation_candidate,22710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23064,curation_candidate,22782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23065,curation_candidate,22787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23066,curation_candidate,22798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23067,curation_candidate,22812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23068,curation_candidate,22927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23069,curation_candidate,22938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23070,curation_candidate,22943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23071,curation_candidate,23008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23072,curation_candidate,23104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23073,curation_candidate,23138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23074,curation_candidate,23156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23075,curation_candidate,23222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23076,curation_candidate,23263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23077,curation_candidate,23335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23078,curation_candidate,23352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23079,curation_candidate,23407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23080,curation_candidate,23436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23081,curation_candidate,23464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23082,curation_candidate,23500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23083,curation_candidate,23532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23084,curation_candidate,23569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23085,curation_candidate,23588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23086,curation_candidate,23617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23087,curation_candidate,23736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23088,curation_candidate,23831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23089,curation_candidate,23838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23090,curation_candidate,23916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23091,curation_candidate,23934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23092,curation_candidate,23941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23093,curation_candidate,23944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23094,curation_candidate,23951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23095,curation_candidate,24024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23096,curation_candidate,24057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23097,curation_candidate,24182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23098,curation_candidate,24433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23099,curation_candidate,24461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23100,curation_candidate,24577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23101,curation_candidate,24581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23102,curation_candidate,24619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23103,curation_candidate,24649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23104,curation_candidate,24732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23105,curation_candidate,24768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23106,curation_candidate,24781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23107,curation_candidate,24789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23108,curation_candidate,24819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23109,curation_candidate,24840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23110,curation_candidate,24881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23111,curation_candidate,24919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23112,curation_candidate,25031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23113,curation_candidate,25137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23114,curation_candidate,25215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23115,curation_candidate,25238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23116,curation_candidate,25349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23117,curation_candidate,25373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23118,curation_candidate,25376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23119,curation_candidate,25414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23120,curation_candidate,25446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23121,curation_candidate,25471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23122,curation_candidate,25544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23123,curation_candidate,25628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23124,curation_candidate,25657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23125,curation_candidate,25739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23126,curation_candidate,25791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23127,curation_candidate,25999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23128,curation_candidate,26086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23129,curation_candidate,26112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23130,curation_candidate,26143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23131,curation_candidate,26156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23132,curation_candidate,26175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23133,curation_candidate,26180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23134,curation_candidate,26225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23135,curation_candidate,26274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23136,curation_candidate,26305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23137,curation_candidate,26372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23138,curation_candidate,26379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23139,curation_candidate,26511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23140,curation_candidate,26520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
23141,curation_candidate,26635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23142,curation_candidate,26754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23143,curation_candidate,26892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23144,curation_candidate,26906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
23145,curation_candidate,26911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23146,curation_candidate,26931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23147,curation_candidate,26956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23148,curation_candidate,26967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23149,curation_candidate,27011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23150,curation_candidate,27068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23151,curation_candidate,27085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23152,curation_candidate,27113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23153,curation_candidate,27432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23154,curation_candidate,27483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23155,curation_candidate,27502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23156,curation_candidate,27564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23157,curation_candidate,27571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23158,curation_candidate,27619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23159,curation_candidate,27671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23160,curation_candidate,27674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23161,curation_candidate,27731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23162,curation_candidate,27748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23163,curation_candidate,27768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23164,curation_candidate,27775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23165,curation_candidate,27836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23166,curation_candidate,27842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23167,curation_candidate,27845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23168,curation_candidate,27873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23169,curation_candidate,27906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23170,curation_candidate,28024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23171,curation_candidate,28216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23172,curation_candidate,28247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23173,curation_candidate,28297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23174,curation_candidate,28329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23175,curation_candidate,28331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23176,curation_candidate,28467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23177,curation_candidate,28509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23178,curation_candidate,28541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23179,curation_candidate,28563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23180,curation_candidate,28578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23181,curation_candidate,28708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23182,curation_candidate,28742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23183,curation_candidate,28896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23184,curation_candidate,29029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23185,curation_candidate,29161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23186,curation_candidate,29187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23187,curation_candidate,29215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23188,curation_candidate,29364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23189,curation_candidate,29365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23190,curation_candidate,29478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23191,curation_candidate,29533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23192,curation_candidate,29540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23193,curation_candidate,29553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23194,curation_candidate,29794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23195,curation_candidate,29900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23196,curation_candidate,30014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23197,curation_candidate,30131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23198,curation_candidate,30259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23199,curation_candidate,30288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23200,curation_candidate,30490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23201,curation_candidate,30748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23202,curation_candidate,30756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23203,curation_candidate,30901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23204,curation_candidate,30969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
23205,curation_candidate,31129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23206,curation_candidate,31237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23207,curation_candidate,31325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23208,curation_candidate,31804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
23209,curation_candidate,31845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23210,curation_candidate,32012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23211,curation_candidate,32177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23212,curation_candidate,32601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23213,curation_candidate,32636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23214,curation_candidate,32936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23215,curation_candidate,32974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23216,curation_candidate,33081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23217,curation_candidate,33385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23218,curation_candidate,33389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23219,curation_candidate,33585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23220,curation_candidate,33680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23221,curation_candidate,33847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23222,curation_candidate,34101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23223,curation_candidate,34134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23224,curation_candidate,34217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23225,curation_candidate,34310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23226,curation_candidate,34782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23227,curation_candidate,34888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23228,curation_candidate,35235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23229,curation_candidate,35292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23230,curation_candidate,35545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23231,curation_candidate,35578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23232,curation_candidate,35586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23233,curation_candidate,35712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23234,curation_candidate,35757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23235,curation_candidate,35811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23236,curation_candidate,35992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23237,curation_candidate,36092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23238,curation_candidate,36363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23239,curation_candidate,36427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23240,curation_candidate,36439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23241,curation_candidate,36550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23242,curation_candidate,36562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23243,curation_candidate,36574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23244,curation_candidate,36683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23245,curation_candidate,36686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23246,curation_candidate,36805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23247,curation_candidate,36892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23248,curation_candidate,36894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23249,curation_candidate,36998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23250,curation_candidate,37001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23251,curation_candidate,37014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23252,curation_candidate,37020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23253,curation_candidate,37043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23254,curation_candidate,37152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23255,curation_candidate,37270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23256,curation_candidate,37334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23257,curation_candidate,37368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23258,curation_candidate,37440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23259,curation_candidate,37612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23260,curation_candidate,37665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23261,curation_candidate,37738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23262,curation_candidate,37775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23263,curation_candidate,37802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23264,curation_candidate,38086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23265,curation_candidate,38101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23266,curation_candidate,16324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23267,curation_candidate,16339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23268,curation_candidate,16354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23269,curation_candidate,16390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23270,curation_candidate,16409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23271,curation_candidate,16422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23272,curation_candidate,16442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23273,curation_candidate,16572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23274,curation_candidate,16595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23275,curation_candidate,16640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23276,curation_candidate,16645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23277,curation_candidate,16657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23278,curation_candidate,16670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23279,curation_candidate,16692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23280,curation_candidate,16713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23281,curation_candidate,16742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23282,curation_candidate,16770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23283,curation_candidate,16926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
23284,curation_candidate,16951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23285,curation_candidate,17114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23286,curation_candidate,17160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23287,curation_candidate,17161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23288,curation_candidate,17174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23289,curation_candidate,17175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23290,curation_candidate,17284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23291,curation_candidate,17285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23292,curation_candidate,17299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23293,curation_candidate,17381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23294,curation_candidate,17401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23295,curation_candidate,17438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23296,curation_candidate,17536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23297,curation_candidate,17553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23298,curation_candidate,17556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23299,curation_candidate,17679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23300,curation_candidate,17703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23301,curation_candidate,17763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23302,curation_candidate,17822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23303,curation_candidate,17906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23304,curation_candidate,17954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23305,curation_candidate,18044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23306,curation_candidate,18117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23307,curation_candidate,18187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23308,curation_candidate,18257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23309,curation_candidate,18346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23310,curation_candidate,18354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23311,curation_candidate,18391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23312,curation_candidate,18401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23313,curation_candidate,18403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23314,curation_candidate,18405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23315,curation_candidate,18437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23316,curation_candidate,18569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23317,curation_candidate,18586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23318,curation_candidate,18596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23319,curation_candidate,18604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23320,curation_candidate,18646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23321,curation_candidate,18740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23322,curation_candidate,18747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23323,curation_candidate,18768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23324,curation_candidate,18788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23325,curation_candidate,18858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23326,curation_candidate,18860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23327,curation_candidate,18863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23328,curation_candidate,18918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23329,curation_candidate,18946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23330,curation_candidate,18955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23331,curation_candidate,18980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23332,curation_candidate,19015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23333,curation_candidate,19075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23334,curation_candidate,19156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23335,curation_candidate,19188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23336,curation_candidate,19192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23337,curation_candidate,19326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23338,curation_candidate,19367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23339,curation_candidate,19394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23340,curation_candidate,19465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23341,curation_candidate,19489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23342,curation_candidate,19491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23343,curation_candidate,19547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23344,curation_candidate,19596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23345,curation_candidate,19699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23346,curation_candidate,19757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23347,curation_candidate,19856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23348,curation_candidate,19868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23349,curation_candidate,19893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23350,curation_candidate,19898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23351,curation_candidate,19906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23352,curation_candidate,19927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23353,curation_candidate,19940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23354,curation_candidate,19955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23355,curation_candidate,20068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23356,curation_candidate,20089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23357,curation_candidate,20242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23358,curation_candidate,20252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23359,curation_candidate,20259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23360,curation_candidate,20298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23361,curation_candidate,20328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23362,curation_candidate,20337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23363,curation_candidate,20339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23364,curation_candidate,20349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23365,curation_candidate,20363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23366,curation_candidate,20364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23367,curation_candidate,20421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23368,curation_candidate,20443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23369,curation_candidate,20451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23370,curation_candidate,20531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23371,curation_candidate,20558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23372,curation_candidate,20591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23373,curation_candidate,20659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23374,curation_candidate,20723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23375,curation_candidate,20813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23376,curation_candidate,20841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23377,curation_candidate,20847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23378,curation_candidate,20848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23379,curation_candidate,20867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23380,curation_candidate,20886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23381,curation_candidate,20900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23382,curation_candidate,20978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23383,curation_candidate,21133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
23384,curation_candidate,21135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23385,curation_candidate,21175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23386,curation_candidate,21318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23387,curation_candidate,21375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23388,curation_candidate,21424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23389,curation_candidate,21429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23390,curation_candidate,21465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23391,curation_candidate,21487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23392,curation_candidate,21555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23393,curation_candidate,21606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23394,curation_candidate,21773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23395,curation_candidate,21827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23396,curation_candidate,21863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23397,curation_candidate,21869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23398,curation_candidate,21909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23399,curation_candidate,22172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23400,curation_candidate,22373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23401,curation_candidate,22386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23402,curation_candidate,22416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23403,curation_candidate,22436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23404,curation_candidate,22508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23405,curation_candidate,22578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23406,curation_candidate,22648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23407,curation_candidate,22676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23408,curation_candidate,22682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23409,curation_candidate,22712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23410,curation_candidate,22788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23411,curation_candidate,22947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23412,curation_candidate,23048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23413,curation_candidate,23068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23414,curation_candidate,23098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23415,curation_candidate,23159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23416,curation_candidate,23173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23417,curation_candidate,23181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23418,curation_candidate,23242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23419,curation_candidate,23278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23420,curation_candidate,23295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23421,curation_candidate,23346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23422,curation_candidate,23394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23423,curation_candidate,23420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23424,curation_candidate,23456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23425,curation_candidate,23481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23426,curation_candidate,23496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23427,curation_candidate,23536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23428,curation_candidate,23572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23429,curation_candidate,23605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23430,curation_candidate,23646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23431,curation_candidate,23656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23432,curation_candidate,23700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23433,curation_candidate,23706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23434,curation_candidate,23734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23435,curation_candidate,23759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23436,curation_candidate,23869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23437,curation_candidate,23881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23438,curation_candidate,23903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23439,curation_candidate,23913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23440,curation_candidate,23922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23441,curation_candidate,24054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23442,curation_candidate,24055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23443,curation_candidate,24141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23444,curation_candidate,24220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23445,curation_candidate,24311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23446,curation_candidate,24366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23447,curation_candidate,24370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23448,curation_candidate,24481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23449,curation_candidate,24523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23450,curation_candidate,24648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
23451,curation_candidate,24667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23452,curation_candidate,24718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23453,curation_candidate,24719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23454,curation_candidate,24727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23455,curation_candidate,24769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23456,curation_candidate,24780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23457,curation_candidate,24793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23458,curation_candidate,24808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23459,curation_candidate,24835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23460,curation_candidate,24866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23461,curation_candidate,24943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23462,curation_candidate,25051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23463,curation_candidate,25068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23464,curation_candidate,25149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23465,curation_candidate,25295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23466,curation_candidate,25302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23467,curation_candidate,25335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23468,curation_candidate,25362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23469,curation_candidate,25372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23470,curation_candidate,25454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23471,curation_candidate,25468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23472,curation_candidate,25500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23473,curation_candidate,25506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23474,curation_candidate,25509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23475,curation_candidate,25525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23476,curation_candidate,25526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23477,curation_candidate,25565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23478,curation_candidate,25566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23479,curation_candidate,25641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23480,curation_candidate,25680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23481,curation_candidate,25691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23482,curation_candidate,25720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23483,curation_candidate,25725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23484,curation_candidate,25731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23485,curation_candidate,25880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23486,curation_candidate,25994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23487,curation_candidate,26129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23488,curation_candidate,26209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23489,curation_candidate,26211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23490,curation_candidate,26271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23491,curation_candidate,26352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23492,curation_candidate,26388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23493,curation_candidate,26457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23494,curation_candidate,26458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23495,curation_candidate,26464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23496,curation_candidate,26515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23497,curation_candidate,26516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23498,curation_candidate,26561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23499,curation_candidate,26628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23500,curation_candidate,26766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23501,curation_candidate,26786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23502,curation_candidate,26792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23503,curation_candidate,26797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23504,curation_candidate,26809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23505,curation_candidate,26838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23506,curation_candidate,26858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23507,curation_candidate,26923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23508,curation_candidate,26959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23509,curation_candidate,26980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23510,curation_candidate,27036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23511,curation_candidate,27141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23512,curation_candidate,27155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23513,curation_candidate,27156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23514,curation_candidate,27188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23515,curation_candidate,27277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23516,curation_candidate,27331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23517,curation_candidate,27341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23518,curation_candidate,27425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23519,curation_candidate,27437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23520,curation_candidate,27468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23521,curation_candidate,27549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23522,curation_candidate,27580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23523,curation_candidate,27724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23524,curation_candidate,27890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23525,curation_candidate,28005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23526,curation_candidate,28007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23527,curation_candidate,28019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23528,curation_candidate,28049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23529,curation_candidate,28093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23530,curation_candidate,28155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23531,curation_candidate,28239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23532,curation_candidate,28314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23533,curation_candidate,28365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23534,curation_candidate,28409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-oligonucleotide editing/silencing modality,2026-06-02T18:08:40+00:00
23535,curation_candidate,28511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23536,curation_candidate,28515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23537,curation_candidate,28605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23538,curation_candidate,28630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23539,curation_candidate,28642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23540,curation_candidate,28710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23541,curation_candidate,28732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23542,curation_candidate,28751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23543,curation_candidate,28842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23544,curation_candidate,28869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23545,curation_candidate,28957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23546,curation_candidate,28970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23547,curation_candidate,29085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23548,curation_candidate,29146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23549,curation_candidate,29155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23550,curation_candidate,29260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23551,curation_candidate,29403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23552,curation_candidate,29597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23553,curation_candidate,29650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23554,curation_candidate,29715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23555,curation_candidate,30088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23556,curation_candidate,30249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23557,curation_candidate,30469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23558,curation_candidate,30543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23559,curation_candidate,30549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23560,curation_candidate,30605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23561,curation_candidate,30710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23562,curation_candidate,30742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23563,curation_candidate,30746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23564,curation_candidate,30928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23565,curation_candidate,31016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23566,curation_candidate,31063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23567,curation_candidate,31153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23568,curation_candidate,31273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23569,curation_candidate,31342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23570,curation_candidate,31420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23571,curation_candidate,31442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23572,curation_candidate,31574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23573,curation_candidate,31609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23574,curation_candidate,32216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23575,curation_candidate,32236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23576,curation_candidate,32243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23577,curation_candidate,32402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23578,curation_candidate,32432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23579,curation_candidate,32492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
23580,curation_candidate,32690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23581,curation_candidate,32695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23582,curation_candidate,32799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23583,curation_candidate,32803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23584,curation_candidate,33304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23585,curation_candidate,33309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23586,curation_candidate,33558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23587,curation_candidate,33606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23588,curation_candidate,33876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23589,curation_candidate,34038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23590,curation_candidate,34146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23591,curation_candidate,34147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23592,curation_candidate,34392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23593,curation_candidate,34449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23594,curation_candidate,34609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23595,curation_candidate,34762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23596,curation_candidate,34873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23597,curation_candidate,34930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23598,curation_candidate,35169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23599,curation_candidate,35187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23600,curation_candidate,35306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23601,curation_candidate,35333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23602,curation_candidate,35400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23603,curation_candidate,35480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23604,curation_candidate,35705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23605,curation_candidate,35796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23606,curation_candidate,35868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23607,curation_candidate,35912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23608,curation_candidate,36141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23609,curation_candidate,36187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
23610,curation_candidate,36374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23611,curation_candidate,36410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23612,curation_candidate,36451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23613,curation_candidate,36713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23614,curation_candidate,36823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23615,curation_candidate,36875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23616,curation_candidate,36884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23617,curation_candidate,36992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23618,curation_candidate,37044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23619,curation_candidate,37061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23620,curation_candidate,37161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23621,curation_candidate,37204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23622,curation_candidate,37392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23623,curation_candidate,37641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23624,curation_candidate,37716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
23625,curation_candidate,38110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23626,curation_candidate,38229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23627,curation_candidate,16358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23628,curation_candidate,16545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23629,curation_candidate,16565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23630,curation_candidate,16678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23631,curation_candidate,16816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23632,curation_candidate,16828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23633,curation_candidate,16832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23634,curation_candidate,16836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23635,curation_candidate,16939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23636,curation_candidate,16949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23637,curation_candidate,16970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23638,curation_candidate,16974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23639,curation_candidate,16975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23640,curation_candidate,16999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23641,curation_candidate,17078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23642,curation_candidate,17098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23643,curation_candidate,17103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23644,curation_candidate,17122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23645,curation_candidate,17191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23646,curation_candidate,17206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23647,curation_candidate,17224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23648,curation_candidate,17247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23649,curation_candidate,17258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23650,curation_candidate,17275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23651,curation_candidate,17343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23652,curation_candidate,17447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23653,curation_candidate,17468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23654,curation_candidate,17517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23655,curation_candidate,17540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23656,curation_candidate,17548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23657,curation_candidate,17551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23658,curation_candidate,17558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23659,curation_candidate,17596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23660,curation_candidate,17610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23661,curation_candidate,17662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23662,curation_candidate,17745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23663,curation_candidate,17840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23664,curation_candidate,17842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23665,curation_candidate,17997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23666,curation_candidate,18015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23667,curation_candidate,18172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23668,curation_candidate,18186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23669,curation_candidate,18222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23670,curation_candidate,18311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23671,curation_candidate,18334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23672,curation_candidate,18414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23673,curation_candidate,18534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23674,curation_candidate,18637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23675,curation_candidate,18648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23676,curation_candidate,18694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23677,curation_candidate,18718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23678,curation_candidate,18834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23679,curation_candidate,18846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23680,curation_candidate,18890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23681,curation_candidate,18975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23682,curation_candidate,18982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23683,curation_candidate,19022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23684,curation_candidate,19073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23685,curation_candidate,19207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23686,curation_candidate,19221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23687,curation_candidate,19237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23688,curation_candidate,19324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23689,curation_candidate,19356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23690,curation_candidate,19432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23691,curation_candidate,19461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23692,curation_candidate,19479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23693,curation_candidate,19508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23694,curation_candidate,19523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23695,curation_candidate,19560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23696,curation_candidate,19591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23697,curation_candidate,19630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23698,curation_candidate,19643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23699,curation_candidate,19703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23700,curation_candidate,19891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23701,curation_candidate,19919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23702,curation_candidate,19983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23703,curation_candidate,20037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23704,curation_candidate,20077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23705,curation_candidate,20080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23706,curation_candidate,20082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23707,curation_candidate,20205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23708,curation_candidate,20211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23709,curation_candidate,20248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23710,curation_candidate,20272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23711,curation_candidate,20347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23712,curation_candidate,20373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23713,curation_candidate,20375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23714,curation_candidate,20413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23715,curation_candidate,20445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23716,curation_candidate,20463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23717,curation_candidate,20465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23718,curation_candidate,20489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23719,curation_candidate,20506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23720,curation_candidate,20546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23721,curation_candidate,20563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23722,curation_candidate,20593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23723,curation_candidate,20609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23724,curation_candidate,20648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23725,curation_candidate,20787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23726,curation_candidate,20928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23727,curation_candidate,20961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23728,curation_candidate,20984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23729,curation_candidate,21006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23730,curation_candidate,21063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23731,curation_candidate,21142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23732,curation_candidate,21174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23733,curation_candidate,21191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23734,curation_candidate,21192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23735,curation_candidate,21277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23736,curation_candidate,21340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23737,curation_candidate,21352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23738,curation_candidate,21355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23739,curation_candidate,21387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23740,curation_candidate,21482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23741,curation_candidate,21550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23742,curation_candidate,21647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23743,curation_candidate,21792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23744,curation_candidate,21798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23745,curation_candidate,21824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23746,curation_candidate,21826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23747,curation_candidate,21845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23748,curation_candidate,21906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23749,curation_candidate,21943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23750,curation_candidate,21993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23751,curation_candidate,22052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23752,curation_candidate,22070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23753,curation_candidate,22138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23754,curation_candidate,22192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23755,curation_candidate,22217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23756,curation_candidate,22221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23757,curation_candidate,22239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23758,curation_candidate,22335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23759,curation_candidate,22383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
23760,curation_candidate,22522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23761,curation_candidate,22654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23762,curation_candidate,22686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23763,curation_candidate,22688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23764,curation_candidate,22700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23765,curation_candidate,22729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23766,curation_candidate,22809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23767,curation_candidate,22860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23768,curation_candidate,22870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23769,curation_candidate,22918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23770,curation_candidate,22919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23771,curation_candidate,22941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23772,curation_candidate,22994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23773,curation_candidate,23001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23774,curation_candidate,23071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23775,curation_candidate,23139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23776,curation_candidate,23175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23777,curation_candidate,23183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23778,curation_candidate,23186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23779,curation_candidate,23212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23780,curation_candidate,23228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23781,curation_candidate,23239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23782,curation_candidate,23245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23783,curation_candidate,23282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23784,curation_candidate,23307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23785,curation_candidate,23311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23786,curation_candidate,23326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23787,curation_candidate,23377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23788,curation_candidate,23450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23789,curation_candidate,23482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23790,curation_candidate,23484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23791,curation_candidate,23518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23792,curation_candidate,23552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23793,curation_candidate,23584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23794,curation_candidate,23638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23795,curation_candidate,23643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23796,curation_candidate,23718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23797,curation_candidate,23814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23798,curation_candidate,23817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23799,curation_candidate,23862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23800,curation_candidate,23907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23801,curation_candidate,24090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23802,curation_candidate,24119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23803,curation_candidate,24223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23804,curation_candidate,24266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23805,curation_candidate,24288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23806,curation_candidate,24324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23807,curation_candidate,24334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23808,curation_candidate,24353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23809,curation_candidate,24418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23810,curation_candidate,24425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23811,curation_candidate,24470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23812,curation_candidate,24475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23813,curation_candidate,24491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23814,curation_candidate,24507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23815,curation_candidate,24552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23816,curation_candidate,24559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23817,curation_candidate,24584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23818,curation_candidate,24590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23819,curation_candidate,24606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23820,curation_candidate,24621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23821,curation_candidate,24631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23822,curation_candidate,24665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23823,curation_candidate,24672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23824,curation_candidate,24674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23825,curation_candidate,24679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23826,curation_candidate,24698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23827,curation_candidate,24741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23828,curation_candidate,24747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23829,curation_candidate,24748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23830,curation_candidate,24796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23831,curation_candidate,24828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23832,curation_candidate,24836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23833,curation_candidate,24855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23834,curation_candidate,24975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23835,curation_candidate,24977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23836,curation_candidate,25055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23837,curation_candidate,25118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23838,curation_candidate,25128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23839,curation_candidate,25169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23840,curation_candidate,25206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23841,curation_candidate,25217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23842,curation_candidate,25242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23843,curation_candidate,25279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23844,curation_candidate,25312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23845,curation_candidate,25391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23846,curation_candidate,25421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23847,curation_candidate,25423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23848,curation_candidate,25464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23849,curation_candidate,25541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23850,curation_candidate,25546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23851,curation_candidate,25555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23852,curation_candidate,25561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23853,curation_candidate,25578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23854,curation_candidate,25600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23855,curation_candidate,25633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23856,curation_candidate,25679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23857,curation_candidate,25769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23858,curation_candidate,25773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23859,curation_candidate,25780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23860,curation_candidate,25861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23861,curation_candidate,25900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23862,curation_candidate,26011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23863,curation_candidate,26043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23864,curation_candidate,26088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23865,curation_candidate,26208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23866,curation_candidate,26278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23867,curation_candidate,26483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
23868,curation_candidate,26510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23869,curation_candidate,26523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23870,curation_candidate,26650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23871,curation_candidate,26693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23872,curation_candidate,26769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23873,curation_candidate,26776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23874,curation_candidate,26863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23875,curation_candidate,26918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23876,curation_candidate,26934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23877,curation_candidate,26943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23878,curation_candidate,26952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23879,curation_candidate,26954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23880,curation_candidate,27019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23881,curation_candidate,27037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23882,curation_candidate,27060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23883,curation_candidate,27083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23884,curation_candidate,27126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23885,curation_candidate,27143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23886,curation_candidate,27261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23887,curation_candidate,27355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23888,curation_candidate,27374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23889,curation_candidate,27527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23890,curation_candidate,27573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23891,curation_candidate,27610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23892,curation_candidate,27666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23893,curation_candidate,27678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23894,curation_candidate,27689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23895,curation_candidate,27745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23896,curation_candidate,27774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23897,curation_candidate,27788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23898,curation_candidate,27848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23899,curation_candidate,27936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23900,curation_candidate,27950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23901,curation_candidate,27962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23902,curation_candidate,27995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23903,curation_candidate,28006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23904,curation_candidate,28021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23905,curation_candidate,28035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23906,curation_candidate,28057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23907,curation_candidate,28058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23908,curation_candidate,28278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23909,curation_candidate,28333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23910,curation_candidate,28362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23911,curation_candidate,28458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23912,curation_candidate,28491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23913,curation_candidate,28520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23914,curation_candidate,28526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23915,curation_candidate,28554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23916,curation_candidate,28829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
23917,curation_candidate,28859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23918,curation_candidate,28867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23919,curation_candidate,28884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23920,curation_candidate,28912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23921,curation_candidate,29063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23922,curation_candidate,29140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23923,curation_candidate,29184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23924,curation_candidate,29254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23925,curation_candidate,29275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23926,curation_candidate,29337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23927,curation_candidate,29392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23928,curation_candidate,29446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23929,curation_candidate,29454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23930,curation_candidate,29469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23931,curation_candidate,29483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23932,curation_candidate,29498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
23933,curation_candidate,29564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23934,curation_candidate,29601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23935,curation_candidate,29630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23936,curation_candidate,29718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23937,curation_candidate,29840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23938,curation_candidate,29871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23939,curation_candidate,29953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23940,curation_candidate,30575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23941,curation_candidate,30624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23942,curation_candidate,30649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23943,curation_candidate,30704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23944,curation_candidate,30767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23945,curation_candidate,30768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23946,curation_candidate,30796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23947,curation_candidate,30819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23948,curation_candidate,30831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23949,curation_candidate,30836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23950,curation_candidate,30947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23951,curation_candidate,31009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23952,curation_candidate,31277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23953,curation_candidate,31324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23954,curation_candidate,31589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23955,curation_candidate,31659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23956,curation_candidate,31680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23957,curation_candidate,31754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23958,curation_candidate,31768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23959,curation_candidate,31775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23960,curation_candidate,31922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23961,curation_candidate,31955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23962,curation_candidate,31980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23963,curation_candidate,32020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23964,curation_candidate,32064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23965,curation_candidate,32217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23966,curation_candidate,32312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23967,curation_candidate,32343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23968,curation_candidate,32382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23969,curation_candidate,32469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
23970,curation_candidate,32484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23971,curation_candidate,32631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23972,curation_candidate,32705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23973,curation_candidate,32804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23974,curation_candidate,33015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23975,curation_candidate,33080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23976,curation_candidate,33200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23977,curation_candidate,33228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23978,curation_candidate,33317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23979,curation_candidate,33365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23980,curation_candidate,33456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23981,curation_candidate,33623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23982,curation_candidate,33758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23983,curation_candidate,33777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
23984,curation_candidate,33918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23985,curation_candidate,34034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23986,curation_candidate,34058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23987,curation_candidate,34094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23988,curation_candidate,34121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23989,curation_candidate,34195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23990,curation_candidate,34209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23991,curation_candidate,34244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23992,curation_candidate,34381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23993,curation_candidate,34386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23994,curation_candidate,34398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23995,curation_candidate,34551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23996,curation_candidate,34676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23997,curation_candidate,34691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
23998,curation_candidate,34815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
23999,curation_candidate,34858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24000,curation_candidate,34903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24001,curation_candidate,35008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24002,curation_candidate,35171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24003,curation_candidate,35227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24004,curation_candidate,35248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24005,curation_candidate,35289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24006,curation_candidate,35305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24007,curation_candidate,35427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24008,curation_candidate,35601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24009,curation_candidate,35638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24010,curation_candidate,35643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24011,curation_candidate,35714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24012,curation_candidate,35718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24013,curation_candidate,35732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24014,curation_candidate,35840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24015,curation_candidate,35989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24016,curation_candidate,36000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24017,curation_candidate,36007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24018,curation_candidate,36096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24019,curation_candidate,36109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24020,curation_candidate,36221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24021,curation_candidate,36247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24022,curation_candidate,36331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24023,curation_candidate,36393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24024,curation_candidate,36466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24025,curation_candidate,36480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24026,curation_candidate,36490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24027,curation_candidate,36588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24028,curation_candidate,36704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24029,curation_candidate,36760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24030,curation_candidate,36775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24031,curation_candidate,36781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24032,curation_candidate,36785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24033,curation_candidate,36790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24034,curation_candidate,36900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24035,curation_candidate,36914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24036,curation_candidate,36931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24037,curation_candidate,36937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24038,curation_candidate,36971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24039,curation_candidate,37004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24040,curation_candidate,37062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24041,curation_candidate,37128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24042,curation_candidate,37249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24043,curation_candidate,37551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24044,curation_candidate,37643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24045,curation_candidate,37880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24046,curation_candidate,37964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24047,curation_candidate,38016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24048,curation_candidate,38192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24049,curation_candidate,38194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24050,curation_candidate,38199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24051,curation_candidate,16337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24052,curation_candidate,16393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24053,curation_candidate,16536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24054,curation_candidate,16610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24055,curation_candidate,16659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24056,curation_candidate,16675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24057,curation_candidate,16745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24058,curation_candidate,16881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24059,curation_candidate,16908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
24060,curation_candidate,17006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24061,curation_candidate,17051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24062,curation_candidate,17110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24063,curation_candidate,17200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24064,curation_candidate,17259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24065,curation_candidate,17267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24066,curation_candidate,17274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24067,curation_candidate,17364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24068,curation_candidate,17471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24069,curation_candidate,17506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24070,curation_candidate,17549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24071,curation_candidate,17585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24072,curation_candidate,17634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24073,curation_candidate,17657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24074,curation_candidate,17690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24075,curation_candidate,17716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24076,curation_candidate,17769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24077,curation_candidate,17795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24078,curation_candidate,17846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24079,curation_candidate,17858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24080,curation_candidate,17865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24081,curation_candidate,17986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24082,curation_candidate,18012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24083,curation_candidate,18130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24084,curation_candidate,18145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24085,curation_candidate,18164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24086,curation_candidate,18189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24087,curation_candidate,18216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24088,curation_candidate,18282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24089,curation_candidate,18284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24090,curation_candidate,18325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24091,curation_candidate,18352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24092,curation_candidate,18376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24093,curation_candidate,18382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24094,curation_candidate,18400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24095,curation_candidate,18425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24096,curation_candidate,18426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24097,curation_candidate,18441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24098,curation_candidate,18460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24099,curation_candidate,18482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24100,curation_candidate,18501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24101,curation_candidate,18677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24102,curation_candidate,18765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24103,curation_candidate,18992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24104,curation_candidate,19113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24105,curation_candidate,19217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24106,curation_candidate,19251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24107,curation_candidate,19268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24108,curation_candidate,19288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24109,curation_candidate,19293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24110,curation_candidate,19294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24111,curation_candidate,19372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24112,curation_candidate,19416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24113,curation_candidate,19511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24114,curation_candidate,19545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24115,curation_candidate,19611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24116,curation_candidate,19668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24117,curation_candidate,19794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24118,curation_candidate,19821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24119,curation_candidate,19851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24120,curation_candidate,19857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24121,curation_candidate,19885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24122,curation_candidate,19917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24123,curation_candidate,19926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24124,curation_candidate,19992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24125,curation_candidate,20013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24126,curation_candidate,20047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24127,curation_candidate,20105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24128,curation_candidate,20134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24129,curation_candidate,20144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24130,curation_candidate,20196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24131,curation_candidate,20268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24132,curation_candidate,20285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24133,curation_candidate,20316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24134,curation_candidate,20318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24135,curation_candidate,20422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24136,curation_candidate,20478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24137,curation_candidate,20480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24138,curation_candidate,20486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24139,curation_candidate,20516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24140,curation_candidate,20537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24141,curation_candidate,20597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24142,curation_candidate,20610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24143,curation_candidate,20654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24144,curation_candidate,20677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24145,curation_candidate,20699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24146,curation_candidate,20763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24147,curation_candidate,20818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24148,curation_candidate,20852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24149,curation_candidate,20899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24150,curation_candidate,20923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24151,curation_candidate,21046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24152,curation_candidate,21126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24153,curation_candidate,21213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24154,curation_candidate,21246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24155,curation_candidate,21255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24156,curation_candidate,21319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24157,curation_candidate,21380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24158,curation_candidate,21411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24159,curation_candidate,21435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24160,curation_candidate,21478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24161,curation_candidate,21483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24162,curation_candidate,21534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24163,curation_candidate,21568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24164,curation_candidate,21599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24165,curation_candidate,21636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24166,curation_candidate,21692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24167,curation_candidate,21716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24168,curation_candidate,21743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24169,curation_candidate,21853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24170,curation_candidate,21861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24171,curation_candidate,21963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24172,curation_candidate,21976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24173,curation_candidate,21985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24174,curation_candidate,22000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24175,curation_candidate,22067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24176,curation_candidate,22099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24177,curation_candidate,22227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24178,curation_candidate,22260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24179,curation_candidate,22280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24180,curation_candidate,22311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24181,curation_candidate,22384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24182,curation_candidate,22440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24183,curation_candidate,22483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24184,curation_candidate,22531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
24185,curation_candidate,22584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24186,curation_candidate,22611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24187,curation_candidate,22684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24188,curation_candidate,22699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24189,curation_candidate,22715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24190,curation_candidate,22758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
24191,curation_candidate,22776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24192,curation_candidate,22869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24193,curation_candidate,22885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24194,curation_candidate,23002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24195,curation_candidate,23010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24196,curation_candidate,23014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24197,curation_candidate,23019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24198,curation_candidate,23026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24199,curation_candidate,23075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24200,curation_candidate,23081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24201,curation_candidate,23108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24202,curation_candidate,23134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24203,curation_candidate,23169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24204,curation_candidate,23187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24205,curation_candidate,23274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24206,curation_candidate,23364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24207,curation_candidate,23506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24208,curation_candidate,23542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24209,curation_candidate,23564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24210,curation_candidate,23570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24211,curation_candidate,23652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24212,curation_candidate,23678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24213,curation_candidate,23717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24214,curation_candidate,23768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24215,curation_candidate,23795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24216,curation_candidate,23825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24217,curation_candidate,23992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24218,curation_candidate,24053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24219,curation_candidate,24075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24220,curation_candidate,24081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24221,curation_candidate,24108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24222,curation_candidate,24133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24223,curation_candidate,24160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24224,curation_candidate,24225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24225,curation_candidate,24248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24226,curation_candidate,24296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24227,curation_candidate,24327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24228,curation_candidate,24337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24229,curation_candidate,24363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24230,curation_candidate,24423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24231,curation_candidate,24459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24232,curation_candidate,24498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24233,curation_candidate,24519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24234,curation_candidate,24530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24235,curation_candidate,24542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24236,curation_candidate,24554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24237,curation_candidate,24555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24238,curation_candidate,24624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24239,curation_candidate,24642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24240,curation_candidate,24658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24241,curation_candidate,24668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24242,curation_candidate,24675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24243,curation_candidate,24716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24244,curation_candidate,24736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24245,curation_candidate,24779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24246,curation_candidate,24785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24247,curation_candidate,24822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24248,curation_candidate,24887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24249,curation_candidate,24897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24250,curation_candidate,24928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24251,curation_candidate,25013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24252,curation_candidate,25035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24253,curation_candidate,25039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24254,curation_candidate,25125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24255,curation_candidate,25143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24256,curation_candidate,25167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24257,curation_candidate,25241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24258,curation_candidate,25292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24259,curation_candidate,25303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24260,curation_candidate,25314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24261,curation_candidate,25327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24262,curation_candidate,25336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24263,curation_candidate,25344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24264,curation_candidate,25353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24265,curation_candidate,25433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24266,curation_candidate,25448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24267,curation_candidate,25449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24268,curation_candidate,25517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24269,curation_candidate,25550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24270,curation_candidate,25587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24271,curation_candidate,25594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24272,curation_candidate,25601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24273,curation_candidate,25631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24274,curation_candidate,25699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24275,curation_candidate,25730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24276,curation_candidate,25760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24277,curation_candidate,25788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24278,curation_candidate,25803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24279,curation_candidate,25888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24280,curation_candidate,25938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24281,curation_candidate,26023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24282,curation_candidate,26152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24283,curation_candidate,26173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24284,curation_candidate,26192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24285,curation_candidate,26241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24286,curation_candidate,26303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24287,curation_candidate,26422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24288,curation_candidate,26951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24289,curation_candidate,27022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24290,curation_candidate,27268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24291,curation_candidate,27396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24292,curation_candidate,27543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24293,curation_candidate,27676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24294,curation_candidate,27693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24295,curation_candidate,27723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24296,curation_candidate,27728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24297,curation_candidate,27742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24298,curation_candidate,27792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24299,curation_candidate,27896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24300,curation_candidate,27920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24301,curation_candidate,27946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24302,curation_candidate,27964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24303,curation_candidate,27998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24304,curation_candidate,28121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24305,curation_candidate,28150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24306,curation_candidate,28221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24307,curation_candidate,28228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24308,curation_candidate,28250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24309,curation_candidate,28340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24310,curation_candidate,28484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24311,curation_candidate,28678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24312,curation_candidate,28684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24313,curation_candidate,28700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24314,curation_candidate,28706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24315,curation_candidate,28757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24316,curation_candidate,28895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24317,curation_candidate,29006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24318,curation_candidate,29035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24319,curation_candidate,29050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24320,curation_candidate,29056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24321,curation_candidate,29094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24322,curation_candidate,29196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24323,curation_candidate,29227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24324,curation_candidate,29235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24325,curation_candidate,29390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24326,curation_candidate,29404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24327,curation_candidate,29530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24328,curation_candidate,29612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24329,curation_candidate,29620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24330,curation_candidate,29627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24331,curation_candidate,29956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24332,curation_candidate,29984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24333,curation_candidate,29990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24334,curation_candidate,30000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
24335,curation_candidate,30162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24336,curation_candidate,30333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24337,curation_candidate,30373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24338,curation_candidate,30496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24339,curation_candidate,30497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24340,curation_candidate,30532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24341,curation_candidate,30542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24342,curation_candidate,30584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24343,curation_candidate,30648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24344,curation_candidate,30774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24345,curation_candidate,30845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24346,curation_candidate,30923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24347,curation_candidate,30935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24348,curation_candidate,31040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24349,curation_candidate,31113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24350,curation_candidate,31176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24351,curation_candidate,31245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24352,curation_candidate,31254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
24353,curation_candidate,31272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24354,curation_candidate,31288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24355,curation_candidate,31335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24356,curation_candidate,31410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24357,curation_candidate,31418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24358,curation_candidate,31614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24359,curation_candidate,31656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24360,curation_candidate,31697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24361,curation_candidate,31894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24362,curation_candidate,31985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24363,curation_candidate,32024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24364,curation_candidate,32109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24365,curation_candidate,32149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
24366,curation_candidate,32250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24367,curation_candidate,32310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24368,curation_candidate,32451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24369,curation_candidate,32506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24370,curation_candidate,32532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24371,curation_candidate,32576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24372,curation_candidate,32604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24373,curation_candidate,32635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24374,curation_candidate,32653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24375,curation_candidate,32791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24376,curation_candidate,33060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24377,curation_candidate,33084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24378,curation_candidate,33165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24379,curation_candidate,33328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24380,curation_candidate,33397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24381,curation_candidate,33399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24382,curation_candidate,33472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24383,curation_candidate,33496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24384,curation_candidate,33570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24385,curation_candidate,33729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24386,curation_candidate,33755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24387,curation_candidate,33761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24388,curation_candidate,33806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24389,curation_candidate,33835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24390,curation_candidate,33877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24391,curation_candidate,33945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24392,curation_candidate,33983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24393,curation_candidate,34030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24394,curation_candidate,34098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24395,curation_candidate,34338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24396,curation_candidate,34522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24397,curation_candidate,34563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24398,curation_candidate,34566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24399,curation_candidate,34573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24400,curation_candidate,34791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24401,curation_candidate,34795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24402,curation_candidate,35029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24403,curation_candidate,35104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24404,curation_candidate,35133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24405,curation_candidate,35151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24406,curation_candidate,35188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24407,curation_candidate,35193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24408,curation_candidate,35246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24409,curation_candidate,35276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24410,curation_candidate,35277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24411,curation_candidate,35348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24412,curation_candidate,35350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24413,curation_candidate,35365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24414,curation_candidate,35685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24415,curation_candidate,35706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24416,curation_candidate,35717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24417,curation_candidate,35724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
24418,curation_candidate,35728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24419,curation_candidate,35750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24420,curation_candidate,35917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24421,curation_candidate,35970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24422,curation_candidate,35976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24423,curation_candidate,35991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24424,curation_candidate,36033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24425,curation_candidate,36055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24426,curation_candidate,36083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24427,curation_candidate,36355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24428,curation_candidate,36380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24429,curation_candidate,36448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24430,curation_candidate,36463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24431,curation_candidate,36473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24432,curation_candidate,36582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24433,curation_candidate,36605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24434,curation_candidate,36623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24435,curation_candidate,36630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24436,curation_candidate,36650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24437,curation_candidate,36660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24438,curation_candidate,36705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24439,curation_candidate,36709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24440,curation_candidate,36851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24441,curation_candidate,36852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24442,curation_candidate,36959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24443,curation_candidate,37076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24444,curation_candidate,37244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24445,curation_candidate,37356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24446,curation_candidate,37367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24447,curation_candidate,37414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24448,curation_candidate,37432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24449,curation_candidate,37506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24450,curation_candidate,37516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24451,curation_candidate,37585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24452,curation_candidate,37642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24453,curation_candidate,37718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24454,curation_candidate,37838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24455,curation_candidate,37881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24456,curation_candidate,37913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24457,curation_candidate,37942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24458,curation_candidate,37972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24459,curation_candidate,38034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24460,curation_candidate,38079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24461,curation_candidate,38279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24462,curation_candidate,38290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24463,curation_candidate,16351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24464,curation_candidate,16395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24465,curation_candidate,16408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24466,curation_candidate,16457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24467,curation_candidate,16462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
24468,curation_candidate,16465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
24469,curation_candidate,16477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24470,curation_candidate,16559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24471,curation_candidate,16689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24472,curation_candidate,16724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24473,curation_candidate,16787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24474,curation_candidate,16820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24475,curation_candidate,16829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24476,curation_candidate,16842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24477,curation_candidate,16865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24478,curation_candidate,16877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24479,curation_candidate,16917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24480,curation_candidate,16989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24481,curation_candidate,17015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24482,curation_candidate,17017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24483,curation_candidate,17033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24484,curation_candidate,17060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24485,curation_candidate,17090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24486,curation_candidate,17109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24487,curation_candidate,17156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24488,curation_candidate,17171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24489,curation_candidate,17211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24490,curation_candidate,17219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24491,curation_candidate,17308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24492,curation_candidate,17312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24493,curation_candidate,17344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24494,curation_candidate,17361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24495,curation_candidate,17521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24496,curation_candidate,17523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24497,curation_candidate,17575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24498,curation_candidate,17607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
24499,curation_candidate,17639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24500,curation_candidate,17701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24501,curation_candidate,17712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24502,curation_candidate,17793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24503,curation_candidate,17853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24504,curation_candidate,17917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24505,curation_candidate,17949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24506,curation_candidate,18050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24507,curation_candidate,18138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24508,curation_candidate,18140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24509,curation_candidate,18144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24510,curation_candidate,18160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24511,curation_candidate,18181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24512,curation_candidate,18234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24513,curation_candidate,18252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24514,curation_candidate,18353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24515,curation_candidate,18393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24516,curation_candidate,18402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24517,curation_candidate,18410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24518,curation_candidate,18532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24519,curation_candidate,18550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24520,curation_candidate,18692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24521,curation_candidate,18709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24522,curation_candidate,18724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24523,curation_candidate,18758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
24524,curation_candidate,18762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24525,curation_candidate,18796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24526,curation_candidate,18956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24527,curation_candidate,19053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24528,curation_candidate,19080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24529,curation_candidate,19096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24530,curation_candidate,19130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24531,curation_candidate,19231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24532,curation_candidate,19245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24533,curation_candidate,19337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24534,curation_candidate,19357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24535,curation_candidate,19358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24536,curation_candidate,19411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24537,curation_candidate,19429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24538,curation_candidate,19430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
24539,curation_candidate,19442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24540,curation_candidate,19513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
24541,curation_candidate,19538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24542,curation_candidate,19613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24543,curation_candidate,19627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24544,curation_candidate,19640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24545,curation_candidate,19685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24546,curation_candidate,19697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24547,curation_candidate,19743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24548,curation_candidate,19754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24549,curation_candidate,19834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24550,curation_candidate,19981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24551,curation_candidate,19987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24552,curation_candidate,20046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24553,curation_candidate,20065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24554,curation_candidate,20103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24555,curation_candidate,20132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24556,curation_candidate,20142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24557,curation_candidate,20173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24558,curation_candidate,20178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24559,curation_candidate,20195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24560,curation_candidate,20260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24561,curation_candidate,20273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24562,curation_candidate,20324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24563,curation_candidate,20355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24564,curation_candidate,20415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24565,curation_candidate,20500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24566,curation_candidate,20536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24567,curation_candidate,20540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24568,curation_candidate,20541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24569,curation_candidate,20590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24570,curation_candidate,20600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24571,curation_candidate,20749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24572,curation_candidate,20781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24573,curation_candidate,20785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24574,curation_candidate,20794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24575,curation_candidate,20836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24576,curation_candidate,20837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24577,curation_candidate,20860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24578,curation_candidate,20885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24579,curation_candidate,20974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24580,curation_candidate,20983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24581,curation_candidate,20995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24582,curation_candidate,21000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
24583,curation_candidate,21005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24584,curation_candidate,21014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24585,curation_candidate,21041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24586,curation_candidate,21061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24587,curation_candidate,21092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24588,curation_candidate,21117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24589,curation_candidate,21122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24590,curation_candidate,21227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24591,curation_candidate,21229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24592,curation_candidate,21232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24593,curation_candidate,21282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24594,curation_candidate,21286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24595,curation_candidate,21288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24596,curation_candidate,21350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24597,curation_candidate,21384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24598,curation_candidate,21450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24599,curation_candidate,21501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24600,curation_candidate,21502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24601,curation_candidate,21520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24602,curation_candidate,21527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24603,curation_candidate,21557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24604,curation_candidate,21579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24605,curation_candidate,21581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24606,curation_candidate,21586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24607,curation_candidate,21664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24608,curation_candidate,21673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24609,curation_candidate,21699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24610,curation_candidate,21717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24611,curation_candidate,21724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24612,curation_candidate,21726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24613,curation_candidate,21735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24614,curation_candidate,21741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24615,curation_candidate,21744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24616,curation_candidate,21745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24617,curation_candidate,21774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24618,curation_candidate,21870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24619,curation_candidate,21892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24620,curation_candidate,21904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24621,curation_candidate,21948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24622,curation_candidate,22012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24623,curation_candidate,22100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24624,curation_candidate,22123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24625,curation_candidate,22126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24626,curation_candidate,22151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24627,curation_candidate,22201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24628,curation_candidate,22211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24629,curation_candidate,22230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24630,curation_candidate,22325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24631,curation_candidate,22371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24632,curation_candidate,22376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24633,curation_candidate,22422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24634,curation_candidate,22429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24635,curation_candidate,22445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24636,curation_candidate,22461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24637,curation_candidate,22516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24638,curation_candidate,22535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
24639,curation_candidate,22550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24640,curation_candidate,22575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24641,curation_candidate,22576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24642,curation_candidate,22594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24643,curation_candidate,22638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
24644,curation_candidate,22666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24645,curation_candidate,22667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24646,curation_candidate,22689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24647,curation_candidate,22690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24648,curation_candidate,22692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24649,curation_candidate,22839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24650,curation_candidate,22857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24651,curation_candidate,22900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24652,curation_candidate,22929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24653,curation_candidate,22991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24654,curation_candidate,23000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24655,curation_candidate,23057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24656,curation_candidate,23065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24657,curation_candidate,23091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24658,curation_candidate,23102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24659,curation_candidate,23116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24660,curation_candidate,23128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24661,curation_candidate,23174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24662,curation_candidate,23182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24663,curation_candidate,23189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24664,curation_candidate,23210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24665,curation_candidate,23237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24666,curation_candidate,23256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24667,curation_candidate,23269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24668,curation_candidate,23292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24669,curation_candidate,23312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24670,curation_candidate,23314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24671,curation_candidate,23397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24672,curation_candidate,23408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24673,curation_candidate,23432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24674,curation_candidate,23457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24675,curation_candidate,23486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24676,curation_candidate,23504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24677,curation_candidate,23559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24678,curation_candidate,23582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24679,curation_candidate,23603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24680,curation_candidate,23604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24681,curation_candidate,23606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24682,curation_candidate,23619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24683,curation_candidate,23698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24684,curation_candidate,23708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24685,curation_candidate,23793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24686,curation_candidate,23824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24687,curation_candidate,23843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24688,curation_candidate,23885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24689,curation_candidate,23915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24690,curation_candidate,23931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24691,curation_candidate,23932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24692,curation_candidate,23969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24693,curation_candidate,24016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24694,curation_candidate,24044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24695,curation_candidate,24046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24696,curation_candidate,24125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24697,curation_candidate,24147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24698,curation_candidate,24197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24699,curation_candidate,24215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24700,curation_candidate,24217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24701,curation_candidate,24237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24702,curation_candidate,24250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24703,curation_candidate,24302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24704,curation_candidate,24318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24705,curation_candidate,24343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24706,curation_candidate,24436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24707,curation_candidate,24613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24708,curation_candidate,24632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24709,curation_candidate,24689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24710,curation_candidate,24700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24711,curation_candidate,24714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24712,curation_candidate,24720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24713,curation_candidate,24746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24714,curation_candidate,24762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24715,curation_candidate,24809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24716,curation_candidate,24829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24717,curation_candidate,24845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24718,curation_candidate,24864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24719,curation_candidate,24932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24720,curation_candidate,24994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24721,curation_candidate,25062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24722,curation_candidate,25093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24723,curation_candidate,25113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24724,curation_candidate,25212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24725,curation_candidate,25247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24726,curation_candidate,25269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24727,curation_candidate,25272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24728,curation_candidate,25338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24729,curation_candidate,25379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24730,curation_candidate,25453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24731,curation_candidate,25472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24732,curation_candidate,25481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24733,curation_candidate,25515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24734,curation_candidate,25579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24735,curation_candidate,25627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24736,curation_candidate,25645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24737,curation_candidate,25666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24738,curation_candidate,25688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24739,curation_candidate,25710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24740,curation_candidate,25713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24741,curation_candidate,25727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24742,curation_candidate,25748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24743,curation_candidate,25759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24744,curation_candidate,25782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24745,curation_candidate,25785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24746,curation_candidate,25856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24747,curation_candidate,25962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24748,curation_candidate,26025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
24749,curation_candidate,26033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24750,curation_candidate,26139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24751,curation_candidate,26154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24752,curation_candidate,26207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24753,curation_candidate,26224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24754,curation_candidate,26238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24755,curation_candidate,26246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24756,curation_candidate,26321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24757,curation_candidate,26382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24758,curation_candidate,26475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24759,curation_candidate,26477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24760,curation_candidate,26632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24761,curation_candidate,26643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24762,curation_candidate,26679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24763,curation_candidate,26699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24764,curation_candidate,26757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24765,curation_candidate,26984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24766,curation_candidate,27079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24767,curation_candidate,27167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24768,curation_candidate,27172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24769,curation_candidate,27211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24770,curation_candidate,27217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24771,curation_candidate,27282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24772,curation_candidate,27352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24773,curation_candidate,27404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24774,curation_candidate,27416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24775,curation_candidate,27429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
24776,curation_candidate,27467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24777,curation_candidate,27471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24778,curation_candidate,27473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24779,curation_candidate,27539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24780,curation_candidate,27540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24781,curation_candidate,27555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24782,curation_candidate,27702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24783,curation_candidate,27716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24784,curation_candidate,27821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24785,curation_candidate,27875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24786,curation_candidate,27940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24787,curation_candidate,27955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24788,curation_candidate,28115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24789,curation_candidate,28194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24790,curation_candidate,28326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24791,curation_candidate,28461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24792,curation_candidate,28463,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24793,curation_candidate,28478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24794,curation_candidate,28621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24795,curation_candidate,28636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24796,curation_candidate,28819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24797,curation_candidate,28944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24798,curation_candidate,28968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24799,curation_candidate,29057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24800,curation_candidate,29225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24801,curation_candidate,29436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
24802,curation_candidate,29523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24803,curation_candidate,29625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24804,curation_candidate,29662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24805,curation_candidate,29951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24806,curation_candidate,30160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24807,curation_candidate,30188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24808,curation_candidate,30202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24809,curation_candidate,30216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24810,curation_candidate,30297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24811,curation_candidate,30337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24812,curation_candidate,30492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24813,curation_candidate,30568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24814,curation_candidate,30570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24815,curation_candidate,30582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24816,curation_candidate,30594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24817,curation_candidate,30640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24818,curation_candidate,30712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24819,curation_candidate,30744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24820,curation_candidate,30806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24821,curation_candidate,30985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24822,curation_candidate,31034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24823,curation_candidate,31093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24824,curation_candidate,31135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24825,curation_candidate,31154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24826,curation_candidate,31378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
24827,curation_candidate,31387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24828,curation_candidate,31388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24829,curation_candidate,31443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24830,curation_candidate,31492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24831,curation_candidate,31500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24832,curation_candidate,31509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24833,curation_candidate,31530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24834,curation_candidate,31565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24835,curation_candidate,31615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24836,curation_candidate,31844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24837,curation_candidate,31879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24838,curation_candidate,31884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24839,curation_candidate,31926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24840,curation_candidate,31951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24841,curation_candidate,31993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24842,curation_candidate,32029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24843,curation_candidate,32083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24844,curation_candidate,32325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24845,curation_candidate,32337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24846,curation_candidate,32397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24847,curation_candidate,32509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24848,curation_candidate,32568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24849,curation_candidate,32618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24850,curation_candidate,32694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24851,curation_candidate,32792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24852,curation_candidate,32809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24853,curation_candidate,32941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24854,curation_candidate,33026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24855,curation_candidate,33068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24856,curation_candidate,33135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24857,curation_candidate,33183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24858,curation_candidate,33223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24859,curation_candidate,33287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24860,curation_candidate,33352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24861,curation_candidate,33367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24862,curation_candidate,33386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24863,curation_candidate,33413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24864,curation_candidate,33501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24865,curation_candidate,33517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24866,curation_candidate,33573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24867,curation_candidate,33597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24868,curation_candidate,33610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24869,curation_candidate,33768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24870,curation_candidate,33930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24871,curation_candidate,34019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24872,curation_candidate,34145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24873,curation_candidate,34149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24874,curation_candidate,34193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24875,curation_candidate,34258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24876,curation_candidate,34282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24877,curation_candidate,34313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24878,curation_candidate,34435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24879,curation_candidate,34492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24880,curation_candidate,34734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24881,curation_candidate,34741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24882,curation_candidate,34796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24883,curation_candidate,34798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24884,curation_candidate,34812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24885,curation_candidate,34847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24886,curation_candidate,34890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24887,curation_candidate,34901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24888,curation_candidate,34975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24889,curation_candidate,34997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24890,curation_candidate,35115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24891,curation_candidate,35148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24892,curation_candidate,35354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24893,curation_candidate,35361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24894,curation_candidate,35387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24895,curation_candidate,35403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24896,curation_candidate,35415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24897,curation_candidate,35420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24898,curation_candidate,35466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24899,curation_candidate,35549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24900,curation_candidate,35613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24901,curation_candidate,35676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24902,curation_candidate,35890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24903,curation_candidate,35932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24904,curation_candidate,36056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24905,curation_candidate,36068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24906,curation_candidate,36097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24907,curation_candidate,36111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24908,curation_candidate,36142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24909,curation_candidate,36145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24910,curation_candidate,36154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24911,curation_candidate,36180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24912,curation_candidate,36185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24913,curation_candidate,36217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24914,curation_candidate,36256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24915,curation_candidate,36273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24916,curation_candidate,36278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24917,curation_candidate,36292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24918,curation_candidate,36336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24919,curation_candidate,36346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24920,curation_candidate,36354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24921,curation_candidate,36398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24922,curation_candidate,36456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24923,curation_candidate,36581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24924,curation_candidate,36645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24925,curation_candidate,36646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24926,curation_candidate,36651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24927,curation_candidate,36654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24928,curation_candidate,36673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24929,curation_candidate,36693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24930,curation_candidate,36810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24931,curation_candidate,36822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24932,curation_candidate,36871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24933,curation_candidate,36950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24934,curation_candidate,37048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24935,curation_candidate,37057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24936,curation_candidate,37111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24937,curation_candidate,37262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24938,curation_candidate,37348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24939,curation_candidate,37407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24940,curation_candidate,37441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24941,curation_candidate,37565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24942,curation_candidate,37613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24943,curation_candidate,37644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24944,curation_candidate,37645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24945,curation_candidate,37646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24946,curation_candidate,37801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24947,curation_candidate,37823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24948,curation_candidate,37877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24949,curation_candidate,37888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24950,curation_candidate,37914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24951,curation_candidate,37943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24952,curation_candidate,37944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24953,curation_candidate,37986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24954,curation_candidate,38038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24955,curation_candidate,38111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24956,curation_candidate,38157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24957,curation_candidate,38196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24958,curation_candidate,38248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24959,curation_candidate,38315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24960,curation_candidate,16341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24961,curation_candidate,16499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24962,curation_candidate,16586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
24963,curation_candidate,16638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24964,curation_candidate,16721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24965,curation_candidate,16748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24966,curation_candidate,16767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24967,curation_candidate,16783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
24968,curation_candidate,16873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is a generic delivery/development obstacle,2026-06-02T18:08:40+00:00
24969,curation_candidate,16879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24970,curation_candidate,16992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24971,curation_candidate,17000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24972,curation_candidate,17018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24973,curation_candidate,17079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24974,curation_candidate,17162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24975,curation_candidate,17262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24976,curation_candidate,17280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24977,curation_candidate,17310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24978,curation_candidate,17334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24979,curation_candidate,17372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24980,curation_candidate,17434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24981,curation_candidate,17440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24982,curation_candidate,17456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24983,curation_candidate,17458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24984,curation_candidate,17501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24985,curation_candidate,17514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24986,curation_candidate,17643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24987,curation_candidate,17656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24988,curation_candidate,17821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
24989,curation_candidate,18011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24990,curation_candidate,18070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24991,curation_candidate,18136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
24992,curation_candidate,18170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24993,curation_candidate,18217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24994,curation_candidate,18221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24995,curation_candidate,18236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24996,curation_candidate,18261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24997,curation_candidate,18275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24998,curation_candidate,18294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
24999,curation_candidate,18297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25000,curation_candidate,18335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25001,curation_candidate,18339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25002,curation_candidate,18341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25003,curation_candidate,18343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25004,curation_candidate,18399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25005,curation_candidate,18406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25006,curation_candidate,18420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25007,curation_candidate,18421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25008,curation_candidate,18431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25009,curation_candidate,18455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25010,curation_candidate,18462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25011,curation_candidate,18478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25012,curation_candidate,18487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25013,curation_candidate,18493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25014,curation_candidate,18497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25015,curation_candidate,18499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25016,curation_candidate,18542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25017,curation_candidate,18600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25018,curation_candidate,18636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25019,curation_candidate,18653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25020,curation_candidate,18697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25021,curation_candidate,18791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25022,curation_candidate,18821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25023,curation_candidate,18825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25024,curation_candidate,18936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25025,curation_candidate,18943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25026,curation_candidate,19014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25027,curation_candidate,19042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25028,curation_candidate,19059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25029,curation_candidate,19106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25030,curation_candidate,19152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25031,curation_candidate,19223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25032,curation_candidate,19226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25033,curation_candidate,19228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25034,curation_candidate,19240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25035,curation_candidate,19241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25036,curation_candidate,19265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25037,curation_candidate,19283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25038,curation_candidate,19305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25039,curation_candidate,19341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25040,curation_candidate,19386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25041,curation_candidate,19406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25042,curation_candidate,19436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25043,curation_candidate,19452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25044,curation_candidate,19502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25045,curation_candidate,19544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25046,curation_candidate,19558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25047,curation_candidate,19683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25048,curation_candidate,19706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
25049,curation_candidate,19720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25050,curation_candidate,19793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25051,curation_candidate,19809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25052,curation_candidate,19822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25053,curation_candidate,19837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25054,curation_candidate,19913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25055,curation_candidate,19943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25056,curation_candidate,19948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25057,curation_candidate,20041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25058,curation_candidate,20050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25059,curation_candidate,20094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25060,curation_candidate,20172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25061,curation_candidate,20198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25062,curation_candidate,20209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25063,curation_candidate,20266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25064,curation_candidate,20279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25065,curation_candidate,20291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25066,curation_candidate,20319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25067,curation_candidate,20322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25068,curation_candidate,20384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25069,curation_candidate,20394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25070,curation_candidate,20410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25071,curation_candidate,20449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25072,curation_candidate,20457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25073,curation_candidate,20460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25074,curation_candidate,20464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25075,curation_candidate,20495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25076,curation_candidate,20509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25077,curation_candidate,20528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25078,curation_candidate,20533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25079,curation_candidate,20583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25080,curation_candidate,20693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25081,curation_candidate,20712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25082,curation_candidate,20713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25083,curation_candidate,20743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25084,curation_candidate,20765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25085,curation_candidate,20797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25086,curation_candidate,20819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25087,curation_candidate,20869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25088,curation_candidate,20893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25089,curation_candidate,21009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25090,curation_candidate,21015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
25091,curation_candidate,21029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25092,curation_candidate,21147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25093,curation_candidate,21160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25094,curation_candidate,21166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25095,curation_candidate,21210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25096,curation_candidate,21223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25097,curation_candidate,21261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25098,curation_candidate,21273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25099,curation_candidate,21284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25100,curation_candidate,21317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25101,curation_candidate,21336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25102,curation_candidate,21341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25103,curation_candidate,21367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25104,curation_candidate,21392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25105,curation_candidate,21395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25106,curation_candidate,21428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25107,curation_candidate,21461,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25108,curation_candidate,21564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
25109,curation_candidate,21580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25110,curation_candidate,21602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25111,curation_candidate,21607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25112,curation_candidate,21645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25113,curation_candidate,21660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25114,curation_candidate,21688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25115,curation_candidate,21736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25116,curation_candidate,21737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25117,curation_candidate,21787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25118,curation_candidate,21788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25119,curation_candidate,21823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25120,curation_candidate,21838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25121,curation_candidate,21841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25122,curation_candidate,21902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25123,curation_candidate,21911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25124,curation_candidate,21946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25125,curation_candidate,21957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25126,curation_candidate,21988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25127,curation_candidate,22034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25128,curation_candidate,22093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25129,curation_candidate,22154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25130,curation_candidate,22164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25131,curation_candidate,22171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25132,curation_candidate,22175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25133,curation_candidate,22198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25134,curation_candidate,22304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25135,curation_candidate,22318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25136,curation_candidate,22364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25137,curation_candidate,22418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25138,curation_candidate,22468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25139,curation_candidate,22476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25140,curation_candidate,22480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25141,curation_candidate,22489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25142,curation_candidate,22491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25143,curation_candidate,22496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25144,curation_candidate,22519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25145,curation_candidate,22553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25146,curation_candidate,22565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25147,curation_candidate,22622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25148,curation_candidate,22718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25149,curation_candidate,22740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25150,curation_candidate,22877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25151,curation_candidate,22897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25152,curation_candidate,22930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25153,curation_candidate,22944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25154,curation_candidate,22975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25155,curation_candidate,22999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25156,curation_candidate,23125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25157,curation_candidate,23229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25158,curation_candidate,23315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25159,curation_candidate,23328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25160,curation_candidate,23380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25161,curation_candidate,23429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25162,curation_candidate,23439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25163,curation_candidate,23459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25164,curation_candidate,23519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25165,curation_candidate,23560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25166,curation_candidate,23599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25167,curation_candidate,23627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25168,curation_candidate,23642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25169,curation_candidate,23659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25170,curation_candidate,23684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25171,curation_candidate,23769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25172,curation_candidate,23788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25173,curation_candidate,23790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25174,curation_candidate,23812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25175,curation_candidate,23850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25176,curation_candidate,23859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25177,curation_candidate,23879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25178,curation_candidate,23894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25179,curation_candidate,23928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25180,curation_candidate,23936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25181,curation_candidate,24028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25182,curation_candidate,24038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25183,curation_candidate,24066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25184,curation_candidate,24115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25185,curation_candidate,24127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25186,curation_candidate,24137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25187,curation_candidate,24204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25188,curation_candidate,24254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25189,curation_candidate,24282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25190,curation_candidate,24283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25191,curation_candidate,24372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25192,curation_candidate,24381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25193,curation_candidate,24391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25194,curation_candidate,24441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25195,curation_candidate,24468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25196,curation_candidate,24469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25197,curation_candidate,24518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25198,curation_candidate,24533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25199,curation_candidate,24568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25200,curation_candidate,24653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25201,curation_candidate,24685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25202,curation_candidate,24695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25203,curation_candidate,24707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25204,curation_candidate,24751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25205,curation_candidate,24794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25206,curation_candidate,24823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25207,curation_candidate,24867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25208,curation_candidate,24870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25209,curation_candidate,24912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25210,curation_candidate,24916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25211,curation_candidate,24997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25212,curation_candidate,25017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25213,curation_candidate,25071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25214,curation_candidate,25123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25215,curation_candidate,25144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25216,curation_candidate,25209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25217,curation_candidate,25223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25218,curation_candidate,25237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25219,curation_candidate,25299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25220,curation_candidate,25329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25221,curation_candidate,25331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25222,curation_candidate,25340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25223,curation_candidate,25345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25224,curation_candidate,25390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25225,curation_candidate,25407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25226,curation_candidate,25466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25227,curation_candidate,25504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25228,curation_candidate,25612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25229,curation_candidate,25623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25230,curation_candidate,25629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25231,curation_candidate,25652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25232,curation_candidate,25673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25233,curation_candidate,25698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25234,curation_candidate,25703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25235,curation_candidate,25714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25236,curation_candidate,25761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25237,curation_candidate,25770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25238,curation_candidate,25845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25239,curation_candidate,25851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25240,curation_candidate,25874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25241,curation_candidate,25968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25242,curation_candidate,25977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25243,curation_candidate,26060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25244,curation_candidate,26065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25245,curation_candidate,26249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25246,curation_candidate,26300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25247,curation_candidate,26414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25248,curation_candidate,26577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25249,curation_candidate,26592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25250,curation_candidate,26606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25251,curation_candidate,26649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25252,curation_candidate,26719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25253,curation_candidate,26730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25254,curation_candidate,26742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25255,curation_candidate,26745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25256,curation_candidate,26787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25257,curation_candidate,26820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25258,curation_candidate,26827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25259,curation_candidate,27021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25260,curation_candidate,27050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25261,curation_candidate,27201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25262,curation_candidate,27357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25263,curation_candidate,27382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25264,curation_candidate,27430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25265,curation_candidate,27431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25266,curation_candidate,27484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25267,curation_candidate,27544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25268,curation_candidate,27581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25269,curation_candidate,27603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25270,curation_candidate,27623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25271,curation_candidate,27684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25272,curation_candidate,27815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25273,curation_candidate,27824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25274,curation_candidate,27853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25275,curation_candidate,27857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25276,curation_candidate,27886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25277,curation_candidate,27971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25278,curation_candidate,27997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25279,curation_candidate,28043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25280,curation_candidate,28075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25281,curation_candidate,28099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25282,curation_candidate,28190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25283,curation_candidate,28242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25284,curation_candidate,28324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25285,curation_candidate,28344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25286,curation_candidate,28383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25287,curation_candidate,28538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25288,curation_candidate,28610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25289,curation_candidate,28647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25290,curation_candidate,28951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25291,curation_candidate,28958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25292,curation_candidate,29177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25293,curation_candidate,29324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25294,curation_candidate,29388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25295,curation_candidate,29903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25296,curation_candidate,29928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25297,curation_candidate,29955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25298,curation_candidate,29997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25299,curation_candidate,30042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25300,curation_candidate,30052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25301,curation_candidate,30086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25302,curation_candidate,30095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25303,curation_candidate,30158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25304,curation_candidate,30175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25305,curation_candidate,30200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25306,curation_candidate,30217,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25307,curation_candidate,30392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25308,curation_candidate,30439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25309,curation_candidate,30441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25310,curation_candidate,30607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25311,curation_candidate,30636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25312,curation_candidate,30815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25313,curation_candidate,30849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25314,curation_candidate,30948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25315,curation_candidate,30998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25316,curation_candidate,31184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25317,curation_candidate,31236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25318,curation_candidate,31267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25319,curation_candidate,31364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25320,curation_candidate,31398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25321,curation_candidate,31407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25322,curation_candidate,31451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25323,curation_candidate,31669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25324,curation_candidate,31743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25325,curation_candidate,31747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25326,curation_candidate,31816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25327,curation_candidate,31869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25328,curation_candidate,31870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25329,curation_candidate,31882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25330,curation_candidate,31941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25331,curation_candidate,31957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25332,curation_candidate,32051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25333,curation_candidate,32089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25334,curation_candidate,32148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25335,curation_candidate,32161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25336,curation_candidate,32292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25337,curation_candidate,32440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25338,curation_candidate,32551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25339,curation_candidate,32685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25340,curation_candidate,32689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25341,curation_candidate,32698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25342,curation_candidate,32781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25343,curation_candidate,32783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25344,curation_candidate,32820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25345,curation_candidate,32823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25346,curation_candidate,32837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25347,curation_candidate,32980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25348,curation_candidate,33077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25349,curation_candidate,33182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25350,curation_candidate,33241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25351,curation_candidate,33269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25352,curation_candidate,33383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25353,curation_candidate,33452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25354,curation_candidate,33462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25355,curation_candidate,33478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25356,curation_candidate,33567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25357,curation_candidate,33593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25358,curation_candidate,33614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25359,curation_candidate,33618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25360,curation_candidate,33639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25361,curation_candidate,33752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25362,curation_candidate,33798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25363,curation_candidate,33851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25364,curation_candidate,33904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25365,curation_candidate,34064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25366,curation_candidate,34091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25367,curation_candidate,34097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25368,curation_candidate,34106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25369,curation_candidate,34135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25370,curation_candidate,34148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25371,curation_candidate,34150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25372,curation_candidate,34196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25373,curation_candidate,34219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25374,curation_candidate,34261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25375,curation_candidate,34302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25376,curation_candidate,34396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25377,curation_candidate,34397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25378,curation_candidate,34429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25379,curation_candidate,34507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25380,curation_candidate,34623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25381,curation_candidate,34719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25382,curation_candidate,34721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25383,curation_candidate,34844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25384,curation_candidate,34845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25385,curation_candidate,34848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25386,curation_candidate,34883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25387,curation_candidate,34914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25388,curation_candidate,34929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25389,curation_candidate,34949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25390,curation_candidate,34992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25391,curation_candidate,35022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25392,curation_candidate,35041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25393,curation_candidate,35127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25394,curation_candidate,35166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25395,curation_candidate,35167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25396,curation_candidate,35168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25397,curation_candidate,35231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25398,curation_candidate,35236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25399,curation_candidate,35264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25400,curation_candidate,35302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25401,curation_candidate,35319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25402,curation_candidate,35331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25403,curation_candidate,35353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25404,curation_candidate,35414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25405,curation_candidate,35423,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25406,curation_candidate,35492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25407,curation_candidate,35522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25408,curation_candidate,35555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25409,curation_candidate,35564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25410,curation_candidate,35589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25411,curation_candidate,35627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25412,curation_candidate,35649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25413,curation_candidate,35663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25414,curation_candidate,35664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25415,curation_candidate,35677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25416,curation_candidate,35687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25417,curation_candidate,35719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25418,curation_candidate,35829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
25419,curation_candidate,35869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25420,curation_candidate,35901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25421,curation_candidate,35908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25422,curation_candidate,35921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25423,curation_candidate,35928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25424,curation_candidate,35969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25425,curation_candidate,36005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25426,curation_candidate,36072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25427,curation_candidate,36095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25428,curation_candidate,36105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25429,curation_candidate,36153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25430,curation_candidate,36202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25431,curation_candidate,36218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25432,curation_candidate,36219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25433,curation_candidate,36268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25434,curation_candidate,36314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25435,curation_candidate,36465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25436,curation_candidate,36478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25437,curation_candidate,36517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25438,curation_candidate,36538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25439,curation_candidate,36616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25440,curation_candidate,36637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25441,curation_candidate,36643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25442,curation_candidate,36685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25443,curation_candidate,36722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25444,curation_candidate,36743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25445,curation_candidate,36829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25446,curation_candidate,36865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25447,curation_candidate,36973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25448,curation_candidate,37072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25449,curation_candidate,37085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25450,curation_candidate,37148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25451,curation_candidate,37171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25452,curation_candidate,37184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25453,curation_candidate,37219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25454,curation_candidate,37335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25455,curation_candidate,37341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25456,curation_candidate,37408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25457,curation_candidate,37469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25458,curation_candidate,37547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25459,curation_candidate,37579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25460,curation_candidate,37647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25461,curation_candidate,37667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25462,curation_candidate,37844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25463,curation_candidate,37853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25464,curation_candidate,37857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25465,curation_candidate,37889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25466,curation_candidate,37915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25467,curation_candidate,37916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25468,curation_candidate,37946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25469,curation_candidate,38055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25470,curation_candidate,38121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25471,curation_candidate,38161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25472,curation_candidate,38289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25473,curation_candidate,16335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25474,curation_candidate,16349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25475,curation_candidate,16517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25476,curation_candidate,16564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25477,curation_candidate,16623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25478,curation_candidate,16656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25479,curation_candidate,16683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25480,curation_candidate,16702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25481,curation_candidate,16786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25482,curation_candidate,16792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
25483,curation_candidate,16813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25484,curation_candidate,16857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25485,curation_candidate,16862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25486,curation_candidate,16883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25487,curation_candidate,16937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
25488,curation_candidate,16962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25489,curation_candidate,17004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25490,curation_candidate,17045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25491,curation_candidate,17061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25492,curation_candidate,17073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25493,curation_candidate,17105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25494,curation_candidate,17186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25495,curation_candidate,17214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25496,curation_candidate,17292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25497,curation_candidate,17300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25498,curation_candidate,17306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25499,curation_candidate,17414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25500,curation_candidate,17455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25501,curation_candidate,17466,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25502,curation_candidate,17491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25503,curation_candidate,17535,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25504,curation_candidate,17576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25505,curation_candidate,17609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25506,curation_candidate,17877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25507,curation_candidate,17901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25508,curation_candidate,17964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25509,curation_candidate,18054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25510,curation_candidate,18090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25511,curation_candidate,18122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25512,curation_candidate,18178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25513,curation_candidate,18180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25514,curation_candidate,18303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25515,curation_candidate,18321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25516,curation_candidate,18362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25517,curation_candidate,18397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25518,curation_candidate,18465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25519,curation_candidate,18467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25520,curation_candidate,18511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25521,curation_candidate,18523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25522,curation_candidate,18524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25523,curation_candidate,18622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25524,curation_candidate,18660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25525,curation_candidate,18671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25526,curation_candidate,18678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25527,curation_candidate,18705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25528,curation_candidate,18792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25529,curation_candidate,18804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25530,curation_candidate,18828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25531,curation_candidate,18831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25532,curation_candidate,18833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25533,curation_candidate,18869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25534,curation_candidate,18994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25535,curation_candidate,19093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25536,curation_candidate,19127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25537,curation_candidate,19131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25538,curation_candidate,19148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25539,curation_candidate,19195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25540,curation_candidate,19224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25541,curation_candidate,19355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25542,curation_candidate,19484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25543,curation_candidate,19543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25544,curation_candidate,19565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25545,curation_candidate,19566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25546,curation_candidate,19569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25547,curation_candidate,19597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25548,curation_candidate,19712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25549,curation_candidate,19714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25550,curation_candidate,19742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25551,curation_candidate,19753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25552,curation_candidate,19763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25553,curation_candidate,19765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25554,curation_candidate,19874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25555,curation_candidate,19909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25556,curation_candidate,19924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25557,curation_candidate,19934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25558,curation_candidate,19991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25559,curation_candidate,20002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25560,curation_candidate,20029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25561,curation_candidate,20049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25562,curation_candidate,20066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25563,curation_candidate,20139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25564,curation_candidate,20176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25565,curation_candidate,20213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25566,curation_candidate,20294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25567,curation_candidate,20341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25568,curation_candidate,20435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25569,curation_candidate,20450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25570,curation_candidate,20491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25571,curation_candidate,20614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25572,curation_candidate,20634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25573,curation_candidate,20643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25574,curation_candidate,20665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25575,curation_candidate,20764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25576,curation_candidate,20769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25577,curation_candidate,20874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25578,curation_candidate,20882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25579,curation_candidate,20953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25580,curation_candidate,21013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25581,curation_candidate,21026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25582,curation_candidate,21033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25583,curation_candidate,21050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25584,curation_candidate,21069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25585,curation_candidate,21079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25586,curation_candidate,21221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25587,curation_candidate,21268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25588,curation_candidate,21271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25589,curation_candidate,21374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25590,curation_candidate,21386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25591,curation_candidate,21409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25592,curation_candidate,21451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25593,curation_candidate,21460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25594,curation_candidate,21468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25595,curation_candidate,21493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25596,curation_candidate,21533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25597,curation_candidate,21545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25598,curation_candidate,21551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25599,curation_candidate,21553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25600,curation_candidate,21604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25601,curation_candidate,21674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25602,curation_candidate,21746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25603,curation_candidate,21769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25604,curation_candidate,21805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25605,curation_candidate,21881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25606,curation_candidate,21982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25607,curation_candidate,21999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25608,curation_candidate,22003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25609,curation_candidate,22022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25610,curation_candidate,22025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25611,curation_candidate,22066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25612,curation_candidate,22153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25613,curation_candidate,22204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25614,curation_candidate,22271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25615,curation_candidate,22279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25616,curation_candidate,22290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25617,curation_candidate,22309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25618,curation_candidate,22336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25619,curation_candidate,22347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25620,curation_candidate,22370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25621,curation_candidate,22391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25622,curation_candidate,22478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25623,curation_candidate,22592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25624,curation_candidate,22599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25625,curation_candidate,22609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25626,curation_candidate,22639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25627,curation_candidate,22733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25628,curation_candidate,22755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25629,curation_candidate,22785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25630,curation_candidate,22842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25631,curation_candidate,22850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25632,curation_candidate,22920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25633,curation_candidate,22931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25634,curation_candidate,22940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25635,curation_candidate,22963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25636,curation_candidate,22972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25637,curation_candidate,23067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25638,curation_candidate,23093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25639,curation_candidate,23153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25640,curation_candidate,23251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25641,curation_candidate,23260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25642,curation_candidate,23262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25643,curation_candidate,23362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25644,curation_candidate,23372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25645,curation_candidate,23376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25646,curation_candidate,23401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25647,curation_candidate,23444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25648,curation_candidate,23453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25649,curation_candidate,23465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25650,curation_candidate,23618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25651,curation_candidate,23633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25652,curation_candidate,23650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25653,curation_candidate,23653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25654,curation_candidate,23696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25655,curation_candidate,23746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25656,curation_candidate,23909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25657,curation_candidate,24027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25658,curation_candidate,24041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25659,curation_candidate,24063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25660,curation_candidate,24138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25661,curation_candidate,24165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25662,curation_candidate,24259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25663,curation_candidate,24269,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25664,curation_candidate,24304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25665,curation_candidate,24368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25666,curation_candidate,24419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25667,curation_candidate,24443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25668,curation_candidate,24553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25669,curation_candidate,24566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25670,curation_candidate,24585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25671,curation_candidate,24591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25672,curation_candidate,24705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25673,curation_candidate,24764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25674,curation_candidate,24766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25675,curation_candidate,24776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25676,curation_candidate,24812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25677,curation_candidate,24825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25678,curation_candidate,24853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25679,curation_candidate,24860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25680,curation_candidate,24883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25681,curation_candidate,24890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25682,curation_candidate,24949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25683,curation_candidate,25004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25684,curation_candidate,25090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25685,curation_candidate,25104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25686,curation_candidate,25124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25687,curation_candidate,25204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25688,curation_candidate,25226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25689,curation_candidate,25227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25690,curation_candidate,25230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25691,curation_candidate,25262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25692,curation_candidate,25276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25693,curation_candidate,25305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25694,curation_candidate,25350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25695,curation_candidate,25401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25696,curation_candidate,25420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25697,curation_candidate,25435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25698,curation_candidate,25462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25699,curation_candidate,25470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25700,curation_candidate,25484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25701,curation_candidate,25487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25702,curation_candidate,25490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25703,curation_candidate,25494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25704,curation_candidate,25495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25705,curation_candidate,25497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25706,curation_candidate,25519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25707,curation_candidate,25539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25708,curation_candidate,25563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25709,curation_candidate,25596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25710,curation_candidate,25606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25711,curation_candidate,25615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25712,curation_candidate,25650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25713,curation_candidate,25787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25714,curation_candidate,25945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25715,curation_candidate,25954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25716,curation_candidate,25978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25717,curation_candidate,25991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25718,curation_candidate,26002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25719,curation_candidate,26309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25720,curation_candidate,26314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25721,curation_candidate,26383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25722,curation_candidate,26528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25723,curation_candidate,26656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25724,curation_candidate,26706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25725,curation_candidate,26707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25726,curation_candidate,26805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25727,curation_candidate,26841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25728,curation_candidate,26856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25729,curation_candidate,27015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25730,curation_candidate,27017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25731,curation_candidate,27048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25732,curation_candidate,27114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25733,curation_candidate,27139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25734,curation_candidate,27206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25735,curation_candidate,27212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25736,curation_candidate,27280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25737,curation_candidate,27478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25738,curation_candidate,27508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25739,curation_candidate,27601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25740,curation_candidate,27700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25741,curation_candidate,27725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25742,curation_candidate,27766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25743,curation_candidate,27831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25744,curation_candidate,27841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25745,curation_candidate,27899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25746,curation_candidate,27972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25747,curation_candidate,27989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25748,curation_candidate,28066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25749,curation_candidate,28074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25750,curation_candidate,28091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25751,curation_candidate,28097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25752,curation_candidate,28146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25753,curation_candidate,28193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25754,curation_candidate,28241,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25755,curation_candidate,28307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25756,curation_candidate,28382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25757,curation_candidate,28405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25758,curation_candidate,28589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25759,curation_candidate,28691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25760,curation_candidate,28699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25761,curation_candidate,28716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25762,curation_candidate,28726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25763,curation_candidate,28880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25764,curation_candidate,28935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25765,curation_candidate,29008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25766,curation_candidate,29096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25767,curation_candidate,29099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25768,curation_candidate,29123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25769,curation_candidate,29236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25770,curation_candidate,29352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25771,curation_candidate,29484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25772,curation_candidate,29590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25773,curation_candidate,29815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25774,curation_candidate,29999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25775,curation_candidate,30136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25776,curation_candidate,30156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25777,curation_candidate,30167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25778,curation_candidate,30187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25779,curation_candidate,30268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25780,curation_candidate,30338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25781,curation_candidate,30344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25782,curation_candidate,30521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25783,curation_candidate,30553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25784,curation_candidate,30596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25785,curation_candidate,30637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25786,curation_candidate,30639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25787,curation_candidate,30650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25788,curation_candidate,30668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25789,curation_candidate,30694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25790,curation_candidate,30740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25791,curation_candidate,30865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25792,curation_candidate,30889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25793,curation_candidate,30907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25794,curation_candidate,30989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25795,curation_candidate,31023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25796,curation_candidate,31071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25797,curation_candidate,31081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25798,curation_candidate,31132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25799,curation_candidate,31152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25800,curation_candidate,31240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25801,curation_candidate,31251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25802,curation_candidate,31456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25803,curation_candidate,31470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25804,curation_candidate,31472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25805,curation_candidate,31476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25806,curation_candidate,31508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25807,curation_candidate,31550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25808,curation_candidate,31606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25809,curation_candidate,31653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25810,curation_candidate,31673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25811,curation_candidate,31778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25812,curation_candidate,31823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25813,curation_candidate,32017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25814,curation_candidate,32222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25815,curation_candidate,32272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25816,curation_candidate,32285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25817,curation_candidate,32352,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25818,curation_candidate,32386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25819,curation_candidate,32456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25820,curation_candidate,32457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25821,curation_candidate,32489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25822,curation_candidate,32494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25823,curation_candidate,32517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25824,curation_candidate,32519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25825,curation_candidate,32544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25826,curation_candidate,32548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25827,curation_candidate,32632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25828,curation_candidate,32692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25829,curation_candidate,32760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25830,curation_candidate,32793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25831,curation_candidate,32859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25832,curation_candidate,32898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25833,curation_candidate,32945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25834,curation_candidate,32988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25835,curation_candidate,33036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25836,curation_candidate,33114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25837,curation_candidate,33160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25838,curation_candidate,33254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25839,curation_candidate,33265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25840,curation_candidate,33493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25841,curation_candidate,33540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25842,curation_candidate,33554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25843,curation_candidate,33771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25844,curation_candidate,33784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25845,curation_candidate,33931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25846,curation_candidate,33968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25847,curation_candidate,34026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25848,curation_candidate,34126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25849,curation_candidate,34137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25850,curation_candidate,34333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25851,curation_candidate,34354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25852,curation_candidate,34356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25853,curation_candidate,34425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25854,curation_candidate,34431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25855,curation_candidate,34440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25856,curation_candidate,34529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25857,curation_candidate,34652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25858,curation_candidate,34655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25859,curation_candidate,34682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25860,curation_candidate,34724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25861,curation_candidate,34802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25862,curation_candidate,34829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25863,curation_candidate,34862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25864,curation_candidate,34911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25865,curation_candidate,34918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25866,curation_candidate,34942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25867,curation_candidate,35030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25868,curation_candidate,35062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25869,curation_candidate,35073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25870,curation_candidate,35160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25871,curation_candidate,35163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25872,curation_candidate,35243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25873,curation_candidate,35275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25874,curation_candidate,35298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25875,curation_candidate,35435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25876,curation_candidate,35501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25877,curation_candidate,35693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25878,curation_candidate,35700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25879,curation_candidate,35733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25880,curation_candidate,35761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25881,curation_candidate,35994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25882,curation_candidate,36008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25883,curation_candidate,36026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25884,curation_candidate,36071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25885,curation_candidate,36177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25886,curation_candidate,36215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25887,curation_candidate,36267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25888,curation_candidate,36304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25889,curation_candidate,36308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25890,curation_candidate,36309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25891,curation_candidate,36326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25892,curation_candidate,36414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25893,curation_candidate,36494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25894,curation_candidate,36521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25895,curation_candidate,36524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25896,curation_candidate,36541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25897,curation_candidate,36663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25898,curation_candidate,36754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25899,curation_candidate,36846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25900,curation_candidate,36856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25901,curation_candidate,36878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25902,curation_candidate,36882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25903,curation_candidate,36902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25904,curation_candidate,36943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25905,curation_candidate,36952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25906,curation_candidate,36991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25907,curation_candidate,37023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25908,curation_candidate,37078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25909,curation_candidate,37091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25910,curation_candidate,37167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25911,curation_candidate,37223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25912,curation_candidate,37233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25913,curation_candidate,37286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25914,curation_candidate,37287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25915,curation_candidate,37445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25916,curation_candidate,37465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25917,curation_candidate,37492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25918,curation_candidate,37522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25919,curation_candidate,37648,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25920,curation_candidate,37698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25921,curation_candidate,37720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25922,curation_candidate,37741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25923,curation_candidate,37751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25924,curation_candidate,37779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25925,curation_candidate,37783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25926,curation_candidate,37962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25927,curation_candidate,38018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25928,curation_candidate,38187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25929,curation_candidate,38210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25930,curation_candidate,16347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25931,curation_candidate,16377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25932,curation_candidate,16497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25933,curation_candidate,16547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25934,curation_candidate,16594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25935,curation_candidate,16597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25936,curation_candidate,16682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25937,curation_candidate,16738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25938,curation_candidate,16763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25939,curation_candidate,16803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25940,curation_candidate,16818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25941,curation_candidate,16866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25942,curation_candidate,16892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25943,curation_candidate,16906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25944,curation_candidate,16913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25945,curation_candidate,16921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25946,curation_candidate,16990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25947,curation_candidate,17003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25948,curation_candidate,17029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25949,curation_candidate,17030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25950,curation_candidate,17036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25951,curation_candidate,17062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25952,curation_candidate,17064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25953,curation_candidate,17085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25954,curation_candidate,17086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25955,curation_candidate,17126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25956,curation_candidate,17141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25957,curation_candidate,17180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25958,curation_candidate,17198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25959,curation_candidate,17202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25960,curation_candidate,17288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25961,curation_candidate,17309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25962,curation_candidate,17331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25963,curation_candidate,17333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25964,curation_candidate,17360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25965,curation_candidate,17384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25966,curation_candidate,17408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25967,curation_candidate,17418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25968,curation_candidate,17445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25969,curation_candidate,17451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25970,curation_candidate,17474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25971,curation_candidate,17494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25972,curation_candidate,17531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25973,curation_candidate,17545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25974,curation_candidate,17588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25975,curation_candidate,17589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25976,curation_candidate,17615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25977,curation_candidate,17779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25978,curation_candidate,17789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25979,curation_candidate,17869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25980,curation_candidate,17878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25981,curation_candidate,17879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25982,curation_candidate,17881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25983,curation_candidate,17892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25984,curation_candidate,17905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25985,curation_candidate,17943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
25986,curation_candidate,17961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
25987,curation_candidate,17967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25988,curation_candidate,17971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25989,curation_candidate,17974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25990,curation_candidate,18005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25991,curation_candidate,18007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25992,curation_candidate,18021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25993,curation_candidate,18099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25994,curation_candidate,18131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
25995,curation_candidate,18156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25996,curation_candidate,18201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25997,curation_candidate,18205,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
25998,curation_candidate,18233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
25999,curation_candidate,18256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26000,curation_candidate,18262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26001,curation_candidate,18287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26002,curation_candidate,18313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26003,curation_candidate,18350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26004,curation_candidate,18383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26005,curation_candidate,18473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26006,curation_candidate,18489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26007,curation_candidate,18502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26008,curation_candidate,18529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26009,curation_candidate,18536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26010,curation_candidate,18540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26011,curation_candidate,18549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26012,curation_candidate,18575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26013,curation_candidate,18582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26014,curation_candidate,18599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26015,curation_candidate,18627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26016,curation_candidate,18634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26017,curation_candidate,18714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26018,curation_candidate,18717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26019,curation_candidate,18893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26020,curation_candidate,18966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26021,curation_candidate,18972,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26022,curation_candidate,18998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26023,curation_candidate,19110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26024,curation_candidate,19117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26025,curation_candidate,19121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26026,curation_candidate,19134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26027,curation_candidate,19144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26028,curation_candidate,19181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26029,curation_candidate,19190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26030,curation_candidate,19382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26031,curation_candidate,19397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26032,curation_candidate,19408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26033,curation_candidate,19433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26034,curation_candidate,19445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26035,curation_candidate,19478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26036,curation_candidate,19485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26037,curation_candidate,19492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26038,curation_candidate,19534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26039,curation_candidate,19555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26040,curation_candidate,19604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26041,curation_candidate,19644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26042,curation_candidate,19745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26043,curation_candidate,19817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26044,curation_candidate,19846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26045,curation_candidate,19848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26046,curation_candidate,19869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26047,curation_candidate,19902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26048,curation_candidate,19907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26049,curation_candidate,19915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26050,curation_candidate,19973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26051,curation_candidate,20001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26052,curation_candidate,20010,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26053,curation_candidate,20055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26054,curation_candidate,20085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26055,curation_candidate,20127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26056,curation_candidate,20204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26057,curation_candidate,20271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26058,curation_candidate,20286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26059,curation_candidate,20325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26060,curation_candidate,20369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26061,curation_candidate,20398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26062,curation_candidate,20442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26063,curation_candidate,20529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26064,curation_candidate,20611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26065,curation_candidate,20617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26066,curation_candidate,20695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26067,curation_candidate,20808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26068,curation_candidate,20831,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26069,curation_candidate,20877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26070,curation_candidate,20880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26071,curation_candidate,20907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26072,curation_candidate,20924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26073,curation_candidate,20929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26074,curation_candidate,21020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26075,curation_candidate,21127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26076,curation_candidate,21185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26077,curation_candidate,21186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26078,curation_candidate,21242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26079,curation_candidate,21276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26080,curation_candidate,21296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26081,curation_candidate,21333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26082,curation_candidate,21344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26083,curation_candidate,21363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26084,curation_candidate,21382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26085,curation_candidate,21405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26086,curation_candidate,21469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26087,curation_candidate,21471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26088,curation_candidate,21556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26089,curation_candidate,21565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26090,curation_candidate,21732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26091,curation_candidate,21825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26092,curation_candidate,21899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26093,curation_candidate,21903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26094,curation_candidate,21938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26095,curation_candidate,21944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26096,curation_candidate,21965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26097,curation_candidate,22014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26098,curation_candidate,22036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26099,curation_candidate,22060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26100,curation_candidate,22071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26101,curation_candidate,22083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26102,curation_candidate,22092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26103,curation_candidate,22159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26104,curation_candidate,22223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26105,curation_candidate,22310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26106,curation_candidate,22351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26107,curation_candidate,22354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26108,curation_candidate,22358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26109,curation_candidate,22380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26110,curation_candidate,22635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26111,curation_candidate,22656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26112,curation_candidate,22685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26113,curation_candidate,22713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26114,curation_candidate,22737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26115,curation_candidate,22741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26116,curation_candidate,22750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26117,curation_candidate,22792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26118,curation_candidate,22861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26119,curation_candidate,22882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26120,curation_candidate,22890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26121,curation_candidate,22891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26122,curation_candidate,22894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26123,curation_candidate,22928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26124,curation_candidate,22935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26125,curation_candidate,22936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26126,curation_candidate,22939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26127,curation_candidate,23059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26128,curation_candidate,23070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26129,curation_candidate,23103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26130,curation_candidate,23216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26131,curation_candidate,23246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26132,curation_candidate,23247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26133,curation_candidate,23275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26134,curation_candidate,23294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26135,curation_candidate,23387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26136,curation_candidate,23455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26137,curation_candidate,23470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26138,curation_candidate,23511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26139,curation_candidate,23533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26140,curation_candidate,23581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26141,curation_candidate,23594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26142,curation_candidate,23752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26143,curation_candidate,23775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26144,curation_candidate,23781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26145,curation_candidate,23846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26146,curation_candidate,23878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26147,curation_candidate,23887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26148,curation_candidate,23917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26149,curation_candidate,23926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26150,curation_candidate,23942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26151,curation_candidate,24026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26152,curation_candidate,24107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26153,curation_candidate,24176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26154,curation_candidate,24200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26155,curation_candidate,24201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26156,curation_candidate,24319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26157,curation_candidate,24380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26158,curation_candidate,24483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26159,curation_candidate,24497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26160,curation_candidate,24505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26161,curation_candidate,24571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26162,curation_candidate,24576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26163,curation_candidate,24580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26164,curation_candidate,24586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26165,curation_candidate,24604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26166,curation_candidate,24704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26167,curation_candidate,24807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26168,curation_candidate,24820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26169,curation_candidate,24885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26170,curation_candidate,24908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26171,curation_candidate,24909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26172,curation_candidate,24953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26173,curation_candidate,24974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26174,curation_candidate,25005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26175,curation_candidate,25016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26176,curation_candidate,25063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26177,curation_candidate,25073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26178,curation_candidate,25077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26179,curation_candidate,25157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26180,curation_candidate,25165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26181,curation_candidate,25260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26182,curation_candidate,25402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26183,curation_candidate,25491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26184,curation_candidate,25503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26185,curation_candidate,25568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26186,curation_candidate,25569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26187,curation_candidate,25602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26188,curation_candidate,25605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26189,curation_candidate,25626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26190,curation_candidate,25667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26191,curation_candidate,25709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26192,curation_candidate,25776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26193,curation_candidate,25777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26194,curation_candidate,25784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26195,curation_candidate,25792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26196,curation_candidate,25801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26197,curation_candidate,25814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26198,curation_candidate,25819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26199,curation_candidate,25836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26200,curation_candidate,25847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26201,curation_candidate,25862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26202,curation_candidate,25878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26203,curation_candidate,25921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26204,curation_candidate,25953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26205,curation_candidate,26074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26206,curation_candidate,26092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26207,curation_candidate,26227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26208,curation_candidate,26348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26209,curation_candidate,26531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26210,curation_candidate,26557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26211,curation_candidate,26563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26212,curation_candidate,26595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26213,curation_candidate,26607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26214,curation_candidate,26689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26215,curation_candidate,26709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26216,curation_candidate,26712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26217,curation_candidate,26839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26218,curation_candidate,26849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26219,curation_candidate,26852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26220,curation_candidate,26915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26221,curation_candidate,27040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26222,curation_candidate,27147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26223,curation_candidate,27363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26224,curation_candidate,27377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26225,curation_candidate,27449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26226,curation_candidate,27523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26227,curation_candidate,27582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26228,curation_candidate,27586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26229,curation_candidate,27596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26230,curation_candidate,27691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26231,curation_candidate,27694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26232,curation_candidate,27732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26233,curation_candidate,27809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26234,curation_candidate,27856,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26235,curation_candidate,27868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26236,curation_candidate,27871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26237,curation_candidate,28065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26238,curation_candidate,28142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26239,curation_candidate,28159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26240,curation_candidate,28163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26241,curation_candidate,28165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26242,curation_candidate,28442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26243,curation_candidate,28452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26244,curation_candidate,28488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26245,curation_candidate,28508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26246,curation_candidate,28513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26247,curation_candidate,28516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26248,curation_candidate,28574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26249,curation_candidate,28590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26250,curation_candidate,28668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26251,curation_candidate,28769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26252,curation_candidate,28771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26253,curation_candidate,28792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26254,curation_candidate,28886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26255,curation_candidate,28933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26256,curation_candidate,28984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26257,curation_candidate,29002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26258,curation_candidate,29194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26259,curation_candidate,29279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26260,curation_candidate,29313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26261,curation_candidate,29567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26262,curation_candidate,29596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26263,curation_candidate,29923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26264,curation_candidate,29937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26265,curation_candidate,30002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26266,curation_candidate,30006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26267,curation_candidate,30081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26268,curation_candidate,30112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26269,curation_candidate,30115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26270,curation_candidate,30152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26271,curation_candidate,30163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26272,curation_candidate,30177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26273,curation_candidate,30201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26274,curation_candidate,30306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26275,curation_candidate,30376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26276,curation_candidate,30378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26277,curation_candidate,30475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26278,curation_candidate,30700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26279,curation_candidate,30713,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26280,curation_candidate,30769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26281,curation_candidate,30853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26282,curation_candidate,30887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26283,curation_candidate,30930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26284,curation_candidate,31035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26285,curation_candidate,31048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26286,curation_candidate,31136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26287,curation_candidate,31164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26288,curation_candidate,31261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26289,curation_candidate,31300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26290,curation_candidate,31315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26291,curation_candidate,31411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26292,curation_candidate,31552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26293,curation_candidate,31598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26294,curation_candidate,31613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26295,curation_candidate,31635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26296,curation_candidate,31694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26297,curation_candidate,31763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26298,curation_candidate,31798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26299,curation_candidate,31812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26300,curation_candidate,31832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26301,curation_candidate,31852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26302,curation_candidate,31863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26303,curation_candidate,31918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26304,curation_candidate,31919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26305,curation_candidate,31938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26306,curation_candidate,32023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26307,curation_candidate,32030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26308,curation_candidate,32125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26309,curation_candidate,32270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26310,curation_candidate,32274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26311,curation_candidate,32328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26312,curation_candidate,32348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26313,curation_candidate,32355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26314,curation_candidate,32505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26315,curation_candidate,32511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26316,curation_candidate,32562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26317,curation_candidate,32565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26318,curation_candidate,32591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26319,curation_candidate,32598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26320,curation_candidate,32599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26321,curation_candidate,32613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26322,curation_candidate,32676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26323,curation_candidate,32729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26324,curation_candidate,32741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26325,curation_candidate,32746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26326,curation_candidate,32870,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26327,curation_candidate,32934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26328,curation_candidate,33029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26329,curation_candidate,33067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26330,curation_candidate,33096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26331,curation_candidate,33138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26332,curation_candidate,33212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26333,curation_candidate,33272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26334,curation_candidate,33285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
26335,curation_candidate,33331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26336,curation_candidate,33364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26337,curation_candidate,33375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26338,curation_candidate,33390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26339,curation_candidate,33398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26340,curation_candidate,33414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26341,curation_candidate,33449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26342,curation_candidate,33457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26343,curation_candidate,33511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26344,curation_candidate,33578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26345,curation_candidate,33596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26346,curation_candidate,33600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26347,curation_candidate,33629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26348,curation_candidate,33640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26349,curation_candidate,33641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26350,curation_candidate,33693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26351,curation_candidate,33750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26352,curation_candidate,33782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26353,curation_candidate,33789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26354,curation_candidate,34296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26355,curation_candidate,34327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26356,curation_candidate,34363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
26357,curation_candidate,34409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26358,curation_candidate,34410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26359,curation_candidate,34447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26360,curation_candidate,34524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26361,curation_candidate,34544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26362,curation_candidate,34567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26363,curation_candidate,34584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26364,curation_candidate,34625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26365,curation_candidate,34637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26366,curation_candidate,34666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26367,curation_candidate,34678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26368,curation_candidate,34703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26369,curation_candidate,34840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26370,curation_candidate,34868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26371,curation_candidate,34889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26372,curation_candidate,34891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26373,curation_candidate,34984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26374,curation_candidate,34998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26375,curation_candidate,35002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26376,curation_candidate,35190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26377,curation_candidate,35345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26378,curation_candidate,35372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26379,curation_candidate,35449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26380,curation_candidate,35543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26381,curation_candidate,35798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26382,curation_candidate,35849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26383,curation_candidate,35891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26384,curation_candidate,35993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26385,curation_candidate,36009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26386,curation_candidate,36197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26387,curation_candidate,36244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26388,curation_candidate,36319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26389,curation_candidate,36647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26390,curation_candidate,37206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26391,curation_candidate,37384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26392,curation_candidate,37409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26393,curation_candidate,37475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26394,curation_candidate,37523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26395,curation_candidate,37650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26396,curation_candidate,37674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26397,curation_candidate,37753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26398,curation_candidate,37947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26399,curation_candidate,38056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26400,curation_candidate,38154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26401,curation_candidate,16322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26402,curation_candidate,16336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26403,curation_candidate,16437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26404,curation_candidate,16491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26405,curation_candidate,16531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26406,curation_candidate,16607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26407,curation_candidate,16672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26408,curation_candidate,16756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
26409,curation_candidate,16843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26410,curation_candidate,16915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26411,curation_candidate,16931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
26412,curation_candidate,16938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26413,curation_candidate,16961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26414,curation_candidate,16973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26415,curation_candidate,16993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26416,curation_candidate,17013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26417,curation_candidate,17035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
26418,curation_candidate,17044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26419,curation_candidate,17048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26420,curation_candidate,17070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26421,curation_candidate,17080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26422,curation_candidate,17088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26423,curation_candidate,17089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26424,curation_candidate,17152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26425,curation_candidate,17223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26426,curation_candidate,17234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26427,curation_candidate,17238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26428,curation_candidate,17391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26429,curation_candidate,17441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26430,curation_candidate,17454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26431,curation_candidate,17464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26432,curation_candidate,17480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26433,curation_candidate,17529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26434,curation_candidate,17577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26435,curation_candidate,17595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26436,curation_candidate,17603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26437,curation_candidate,17605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26438,curation_candidate,17621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26439,curation_candidate,17623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26440,curation_candidate,17660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26441,curation_candidate,17691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26442,curation_candidate,17695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26443,curation_candidate,17710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26444,curation_candidate,17740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26445,curation_candidate,17759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26446,curation_candidate,17790,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26447,curation_candidate,17799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26448,curation_candidate,17922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26449,curation_candidate,17962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26450,curation_candidate,17969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26451,curation_candidate,17978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26452,curation_candidate,18057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26453,curation_candidate,18059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26454,curation_candidate,18076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26455,curation_candidate,18102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26456,curation_candidate,18190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26457,curation_candidate,18202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26458,curation_candidate,18246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26459,curation_candidate,18267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26460,curation_candidate,18285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26461,curation_candidate,18355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26462,curation_candidate,18445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26463,curation_candidate,18452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26464,curation_candidate,18468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26465,curation_candidate,18538,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26466,curation_candidate,18547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
26467,curation_candidate,18593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26468,curation_candidate,18612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26469,curation_candidate,18658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26470,curation_candidate,18682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26471,curation_candidate,18686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26472,curation_candidate,18735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26473,curation_candidate,18744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26474,curation_candidate,18770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26475,curation_candidate,18783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26476,curation_candidate,18800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26477,curation_candidate,18826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26478,curation_candidate,18895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26479,curation_candidate,18905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26480,curation_candidate,18913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26481,curation_candidate,18923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26482,curation_candidate,18993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26483,curation_candidate,19003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26484,curation_candidate,19032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26485,curation_candidate,19039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26486,curation_candidate,19105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26487,curation_candidate,19139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26488,curation_candidate,19180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26489,curation_candidate,19282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26490,curation_candidate,19302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26491,curation_candidate,19360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26492,curation_candidate,19395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26493,curation_candidate,19471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26494,curation_candidate,19524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26495,curation_candidate,19533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26496,curation_candidate,19541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26497,curation_candidate,19603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26498,curation_candidate,19628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26499,curation_candidate,19670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26500,curation_candidate,19678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26501,curation_candidate,19710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26502,curation_candidate,19775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26503,curation_candidate,19782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26504,curation_candidate,19784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26505,curation_candidate,19800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26506,curation_candidate,19825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26507,curation_candidate,19826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26508,curation_candidate,19867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26509,curation_candidate,19882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26510,curation_candidate,19887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26511,curation_candidate,19895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26512,curation_candidate,19925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26513,curation_candidate,19974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26514,curation_candidate,20015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26515,curation_candidate,20169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26516,curation_candidate,20184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26517,curation_candidate,20190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26518,curation_candidate,20201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26519,curation_candidate,20238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26520,curation_candidate,20270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26521,curation_candidate,20309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26522,curation_candidate,20372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26523,curation_candidate,20407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26524,curation_candidate,20431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26525,curation_candidate,20545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26526,curation_candidate,20569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26527,curation_candidate,20655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26528,curation_candidate,20688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26529,curation_candidate,20708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26530,curation_candidate,20742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26531,curation_candidate,20777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26532,curation_candidate,20810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26533,curation_candidate,20840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26534,curation_candidate,20887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26535,curation_candidate,20897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26536,curation_candidate,20927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26537,curation_candidate,20952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26538,curation_candidate,20997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26539,curation_candidate,21017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26540,curation_candidate,21028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26541,curation_candidate,21060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26542,curation_candidate,21076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26543,curation_candidate,21099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26544,curation_candidate,21206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26545,curation_candidate,21266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26546,curation_candidate,21267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26547,curation_candidate,21339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26548,curation_candidate,21388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26549,curation_candidate,21403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26550,curation_candidate,21420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26551,curation_candidate,21426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26552,curation_candidate,21512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26553,curation_candidate,21566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26554,curation_candidate,21625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26555,curation_candidate,21643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26556,curation_candidate,21722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26557,curation_candidate,21901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26558,curation_candidate,21910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26559,curation_candidate,21912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26560,curation_candidate,21941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26561,curation_candidate,21953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26562,curation_candidate,21990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26563,curation_candidate,21997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26564,curation_candidate,22004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26565,curation_candidate,22062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26566,curation_candidate,22129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26567,curation_candidate,22183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26568,curation_candidate,22209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26569,curation_candidate,22238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26570,curation_candidate,22255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26571,curation_candidate,22262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26572,curation_candidate,22344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26573,curation_candidate,22481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26574,curation_candidate,22607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26575,curation_candidate,22664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26576,curation_candidate,22719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26577,curation_candidate,22732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26578,curation_candidate,22770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26579,curation_candidate,22783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26580,curation_candidate,22805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26581,curation_candidate,22858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26582,curation_candidate,22896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26583,curation_candidate,23046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26584,curation_candidate,23083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26585,curation_candidate,23087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26586,curation_candidate,23122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26587,curation_candidate,23198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26588,curation_candidate,23249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26589,curation_candidate,23273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26590,curation_candidate,23289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26591,curation_candidate,23353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26592,curation_candidate,23400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26593,curation_candidate,23434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26594,curation_candidate,23476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26595,curation_candidate,23495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26596,curation_candidate,23501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26597,curation_candidate,23537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26598,curation_candidate,23611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26599,curation_candidate,23660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26600,curation_candidate,23661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26601,curation_candidate,23697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26602,curation_candidate,23703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26603,curation_candidate,23745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26604,curation_candidate,23764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26605,curation_candidate,23797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26606,curation_candidate,23876,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26607,curation_candidate,23921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26608,curation_candidate,23935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26609,curation_candidate,23953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
26610,curation_candidate,23954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26611,curation_candidate,23976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26612,curation_candidate,23980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26613,curation_candidate,23987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26614,curation_candidate,24012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26615,curation_candidate,24020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26616,curation_candidate,24023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26617,curation_candidate,24037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26618,curation_candidate,24092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26619,curation_candidate,24164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26620,curation_candidate,24181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26621,curation_candidate,24287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26622,curation_candidate,24389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26623,curation_candidate,24392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26624,curation_candidate,24442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26625,curation_candidate,24487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26626,curation_candidate,24495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26627,curation_candidate,24550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26628,curation_candidate,24565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26629,curation_candidate,24609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26630,curation_candidate,24644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26631,curation_candidate,24678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26632,curation_candidate,24709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26633,curation_candidate,24797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26634,curation_candidate,24861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26635,curation_candidate,24872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26636,curation_candidate,24874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26637,curation_candidate,24896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26638,curation_candidate,24965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26639,curation_candidate,25019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26640,curation_candidate,25058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26641,curation_candidate,25083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26642,curation_candidate,25097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26643,curation_candidate,25105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26644,curation_candidate,25119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26645,curation_candidate,25148,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26646,curation_candidate,25160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26647,curation_candidate,25198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26648,curation_candidate,25214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26649,curation_candidate,25228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26650,curation_candidate,25294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26651,curation_candidate,25341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26652,curation_candidate,25342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26653,curation_candidate,25366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26654,curation_candidate,25427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26655,curation_candidate,25432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26656,curation_candidate,25469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26657,curation_candidate,25501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26658,curation_candidate,25514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26659,curation_candidate,25543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26660,curation_candidate,25552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26661,curation_candidate,25696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26662,curation_candidate,25702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26663,curation_candidate,25796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26664,curation_candidate,25802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26665,curation_candidate,25973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26666,curation_candidate,26047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26667,curation_candidate,26079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26668,curation_candidate,26307,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26669,curation_candidate,26545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26670,curation_candidate,26560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26671,curation_candidate,26578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26672,curation_candidate,26612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26673,curation_candidate,26678,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26674,curation_candidate,26731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26675,curation_candidate,26789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26676,curation_candidate,26846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26677,curation_candidate,26871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26678,curation_candidate,26887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26679,curation_candidate,26922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26680,curation_candidate,26996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26681,curation_candidate,27202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26682,curation_candidate,27251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26683,curation_candidate,27441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26684,curation_candidate,27445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26685,curation_candidate,27491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26686,curation_candidate,27585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26687,curation_candidate,27673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26688,curation_candidate,27699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26689,curation_candidate,27733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26690,curation_candidate,27833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26691,curation_candidate,27859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26692,curation_candidate,27921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26693,curation_candidate,27930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26694,curation_candidate,27933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26695,curation_candidate,27960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26696,curation_candidate,27976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26697,curation_candidate,28055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26698,curation_candidate,28086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26699,curation_candidate,28087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26700,curation_candidate,28174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26701,curation_candidate,28267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26702,curation_candidate,28441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26703,curation_candidate,28460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26704,curation_candidate,28517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26705,curation_candidate,28565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26706,curation_candidate,28675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26707,curation_candidate,28698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26708,curation_candidate,28731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26709,curation_candidate,28761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26710,curation_candidate,28786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
26711,curation_candidate,28877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26712,curation_candidate,28904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26713,curation_candidate,28915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26714,curation_candidate,28965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26715,curation_candidate,29139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26716,curation_candidate,29261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26717,curation_candidate,29316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26718,curation_candidate,30079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26719,curation_candidate,30111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26720,curation_candidate,30180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26721,curation_candidate,30195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26722,curation_candidate,30275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26723,curation_candidate,30290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26724,curation_candidate,30353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26725,curation_candidate,30369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26726,curation_candidate,30424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26727,curation_candidate,30454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26728,curation_candidate,30503,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26729,curation_candidate,30506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26730,curation_candidate,30775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26731,curation_candidate,30844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26732,curation_candidate,31052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26733,curation_candidate,31057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26734,curation_candidate,31058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26735,curation_candidate,31062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26736,curation_candidate,31122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26737,curation_candidate,31133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26738,curation_candidate,31187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26739,curation_candidate,31188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26740,curation_candidate,31196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26741,curation_candidate,31198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26742,curation_candidate,31203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26743,curation_candidate,31243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26744,curation_candidate,31248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26745,curation_candidate,31465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26746,curation_candidate,31473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26747,curation_candidate,31475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26748,curation_candidate,31773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26749,curation_candidate,31836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26750,curation_candidate,31862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26751,curation_candidate,31893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26752,curation_candidate,31930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26753,curation_candidate,31992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26754,curation_candidate,32002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26755,curation_candidate,32013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26756,curation_candidate,32245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26757,curation_candidate,32280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26758,curation_candidate,32281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26759,curation_candidate,32335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26760,curation_candidate,32441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26761,curation_candidate,32447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26762,curation_candidate,32482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26763,curation_candidate,32486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26764,curation_candidate,32501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26765,curation_candidate,32556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26766,curation_candidate,32564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26767,curation_candidate,32589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26768,curation_candidate,32592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26769,curation_candidate,32628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26770,curation_candidate,32657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26771,curation_candidate,32668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26772,curation_candidate,32671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26773,curation_candidate,32735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26774,curation_candidate,32750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26775,curation_candidate,32769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26776,curation_candidate,32821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26777,curation_candidate,32852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26778,curation_candidate,32873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26779,curation_candidate,32923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26780,curation_candidate,32929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26781,curation_candidate,33017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26782,curation_candidate,33110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26783,curation_candidate,33117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26784,curation_candidate,33156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26785,curation_candidate,33181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26786,curation_candidate,33264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26787,curation_candidate,33273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26788,curation_candidate,33291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26789,curation_candidate,33300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26790,curation_candidate,33337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26791,curation_candidate,33438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26792,curation_candidate,33524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26793,curation_candidate,33660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26794,curation_candidate,33682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26795,curation_candidate,33756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26796,curation_candidate,33799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26797,curation_candidate,33873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26798,curation_candidate,33929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26799,curation_candidate,33987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26800,curation_candidate,34025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26801,curation_candidate,34066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26802,curation_candidate,34067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26803,curation_candidate,34072,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26804,curation_candidate,34095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26805,curation_candidate,34125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26806,curation_candidate,34181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26807,curation_candidate,34190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26808,curation_candidate,34227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26809,curation_candidate,34328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26810,curation_candidate,34334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26811,curation_candidate,34337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26812,curation_candidate,34368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26813,curation_candidate,34395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26814,curation_candidate,34406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26815,curation_candidate,34491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26816,curation_candidate,34533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26817,curation_candidate,34561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26818,curation_candidate,34669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26819,curation_candidate,34670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26820,curation_candidate,34728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26821,curation_candidate,34758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26822,curation_candidate,34777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26823,curation_candidate,34817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26824,curation_candidate,34863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26825,curation_candidate,34935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26826,curation_candidate,34976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26827,curation_candidate,34985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26828,curation_candidate,35014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26829,curation_candidate,35043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26830,curation_candidate,35059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26831,curation_candidate,35090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26832,curation_candidate,35272,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26833,curation_candidate,35362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26834,curation_candidate,35481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26835,curation_candidate,35645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26836,curation_candidate,35656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26837,curation_candidate,35694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26838,curation_candidate,35762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26839,curation_candidate,35847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26840,curation_candidate,35850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26841,curation_candidate,35984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26842,curation_candidate,36030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26843,curation_candidate,36075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26844,curation_candidate,36106,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26845,curation_candidate,36361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26846,curation_candidate,36381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26847,curation_candidate,36474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26848,curation_candidate,36632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26849,curation_candidate,36690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26850,curation_candidate,36721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26851,curation_candidate,36778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26852,curation_candidate,36970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26853,curation_candidate,36990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26854,curation_candidate,37200,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26855,curation_candidate,37234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26856,curation_candidate,37349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26857,curation_candidate,37425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26858,curation_candidate,37481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26859,curation_candidate,37524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26860,curation_candidate,37525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26861,curation_candidate,37616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26862,curation_candidate,37680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no oligonucleotide modality linked to off-target evidence,2026-06-02T18:08:40+00:00
26863,curation_candidate,37784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26864,curation_candidate,37785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26865,curation_candidate,37814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26866,curation_candidate,37860,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26867,curation_candidate,37966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26868,curation_candidate,38057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26869,curation_candidate,38058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26870,curation_candidate,38087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26871,curation_candidate,38127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26872,curation_candidate,38164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26873,curation_candidate,38165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26874,curation_candidate,38280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26875,curation_candidate,38282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26876,curation_candidate,16411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26877,curation_candidate,16550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26878,curation_candidate,16662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26879,curation_candidate,16665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26880,curation_candidate,16680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26881,curation_candidate,16717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26882,curation_candidate,16740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26883,curation_candidate,16807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26884,curation_candidate,16811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26885,curation_candidate,16885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26886,curation_candidate,16887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26887,curation_candidate,16907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26888,curation_candidate,16946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26889,curation_candidate,16982,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26890,curation_candidate,16984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26891,curation_candidate,16996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26892,curation_candidate,17016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26893,curation_candidate,17037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26894,curation_candidate,17038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26895,curation_candidate,17067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26896,curation_candidate,17082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26897,curation_candidate,17084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26898,curation_candidate,17107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26899,curation_candidate,17127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26900,curation_candidate,17139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26901,curation_candidate,17145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26902,curation_candidate,17235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26903,curation_candidate,17279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26904,curation_candidate,17311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26905,curation_candidate,17322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26906,curation_candidate,17362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26907,curation_candidate,17368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26908,curation_candidate,17377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26909,curation_candidate,17387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26910,curation_candidate,17390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26911,curation_candidate,17397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26912,curation_candidate,17410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26913,curation_candidate,17443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26914,curation_candidate,17488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26915,curation_candidate,17493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26916,curation_candidate,17499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26917,curation_candidate,17512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26918,curation_candidate,17519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26919,curation_candidate,17555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26920,curation_candidate,17569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26921,curation_candidate,17638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26922,curation_candidate,17671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26923,curation_candidate,17733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26924,curation_candidate,17776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26925,curation_candidate,17815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26926,curation_candidate,17823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26927,curation_candidate,17839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26928,curation_candidate,17844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26929,curation_candidate,17852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26930,curation_candidate,17874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26931,curation_candidate,17948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26932,curation_candidate,17959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26933,curation_candidate,17973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26934,curation_candidate,18046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26935,curation_candidate,18060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26936,curation_candidate,18105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26937,curation_candidate,18228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26938,curation_candidate,18251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26939,curation_candidate,18296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26940,curation_candidate,18317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26941,curation_candidate,18407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26942,curation_candidate,18419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26943,curation_candidate,18424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26944,curation_candidate,18498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26945,curation_candidate,18558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26946,curation_candidate,18572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26947,curation_candidate,18574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26948,curation_candidate,18598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26949,curation_candidate,18642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26950,curation_candidate,18666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26951,curation_candidate,18674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26952,curation_candidate,18766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26953,curation_candidate,18772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26954,curation_candidate,18777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26955,curation_candidate,19026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26956,curation_candidate,19031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26957,curation_candidate,19087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26958,curation_candidate,19092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26959,curation_candidate,19100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26960,curation_candidate,19124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26961,curation_candidate,19143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26962,curation_candidate,19189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26963,curation_candidate,19203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26964,curation_candidate,19208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26965,curation_candidate,19253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26966,curation_candidate,19256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26967,curation_candidate,19266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26968,curation_candidate,19275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26969,curation_candidate,19310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26970,curation_candidate,19335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26971,curation_candidate,19376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26972,curation_candidate,19403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26973,curation_candidate,19410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26974,curation_candidate,19417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26975,curation_candidate,19510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26976,curation_candidate,19548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26977,curation_candidate,19582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26978,curation_candidate,19585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26979,curation_candidate,19590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26980,curation_candidate,19624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
26981,curation_candidate,19661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26982,curation_candidate,19682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26983,curation_candidate,19732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
26984,curation_candidate,19756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26985,curation_candidate,19760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26986,curation_candidate,19812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26987,curation_candidate,19889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26988,curation_candidate,19928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26989,curation_candidate,19996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26990,curation_candidate,20018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26991,curation_candidate,20063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26992,curation_candidate,20074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26993,curation_candidate,20100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26994,curation_candidate,20160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26995,curation_candidate,20166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26996,curation_candidate,20220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
26997,curation_candidate,20221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
26998,curation_candidate,20229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
26999,curation_candidate,20234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27000,curation_candidate,20258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27001,curation_candidate,20288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27002,curation_candidate,20297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27003,curation_candidate,20416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27004,curation_candidate,20417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27005,curation_candidate,20426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27006,curation_candidate,20434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27007,curation_candidate,20446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27008,curation_candidate,20470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27009,curation_candidate,20512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27010,curation_candidate,20565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
27011,curation_candidate,20584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27012,curation_candidate,20589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27013,curation_candidate,20602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27014,curation_candidate,20623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27015,curation_candidate,20637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27016,curation_candidate,20652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27017,curation_candidate,20668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27018,curation_candidate,20674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27019,curation_candidate,20706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27020,curation_candidate,20726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27021,curation_candidate,20796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27022,curation_candidate,20822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27023,curation_candidate,20862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27024,curation_candidate,20976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27025,curation_candidate,20985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27026,curation_candidate,20994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27027,curation_candidate,21019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27028,curation_candidate,21085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27029,curation_candidate,21100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27030,curation_candidate,21134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27031,curation_candidate,21176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27032,curation_candidate,21194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27033,curation_candidate,21238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27034,curation_candidate,21245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27035,curation_candidate,21251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27036,curation_candidate,21292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27037,curation_candidate,21305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27038,curation_candidate,21361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27039,curation_candidate,21398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27040,curation_candidate,21414,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27041,curation_candidate,21449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27042,curation_candidate,21452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27043,curation_candidate,21473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27044,curation_candidate,21614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27045,curation_candidate,21617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27046,curation_candidate,21650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27047,curation_candidate,21680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27048,curation_candidate,21755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27049,curation_candidate,21780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27050,curation_candidate,21795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27051,curation_candidate,21802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27052,curation_candidate,21814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27053,curation_candidate,21849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27054,curation_candidate,21862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27055,curation_candidate,21897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27056,curation_candidate,21908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27057,curation_candidate,21932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27058,curation_candidate,21952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27059,curation_candidate,21956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27060,curation_candidate,21986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27061,curation_candidate,22041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27062,curation_candidate,22077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27063,curation_candidate,22095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27064,curation_candidate,22160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27065,curation_candidate,22182,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27066,curation_candidate,22299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27067,curation_candidate,22327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27068,curation_candidate,22337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27069,curation_candidate,22341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27070,curation_candidate,22400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27071,curation_candidate,22419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27072,curation_candidate,22451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27073,curation_candidate,22709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27074,curation_candidate,22794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27075,curation_candidate,22796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27076,curation_candidate,22822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27077,curation_candidate,22823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27078,curation_candidate,22906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27079,curation_candidate,22937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27080,curation_candidate,22960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27081,curation_candidate,23131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27082,curation_candidate,23166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27083,curation_candidate,23204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27084,curation_candidate,23305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27085,curation_candidate,23343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27086,curation_candidate,23448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27087,curation_candidate,23493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27088,curation_candidate,23497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27089,curation_candidate,23498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27090,curation_candidate,23553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27091,curation_candidate,23722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27092,curation_candidate,23756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27093,curation_candidate,23837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27094,curation_candidate,23848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27095,curation_candidate,23858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27096,curation_candidate,23974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27097,curation_candidate,23988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27098,curation_candidate,24002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27099,curation_candidate,24004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27100,curation_candidate,24052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27101,curation_candidate,24068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27102,curation_candidate,24102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27103,curation_candidate,24178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27104,curation_candidate,24236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27105,curation_candidate,24253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27106,curation_candidate,24264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27107,curation_candidate,24268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27108,curation_candidate,24281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27109,curation_candidate,24286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27110,curation_candidate,24295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27111,curation_candidate,24305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27112,curation_candidate,24341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27113,curation_candidate,24344,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27114,curation_candidate,24345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27115,curation_candidate,24430,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27116,curation_candidate,24528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27117,curation_candidate,24598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27118,curation_candidate,24607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27119,curation_candidate,24877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27120,curation_candidate,24900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27121,curation_candidate,24934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27122,curation_candidate,24957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27123,curation_candidate,25029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27124,curation_candidate,25066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27125,curation_candidate,25078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27126,curation_candidate,25189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27127,curation_candidate,25211,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27128,curation_candidate,25218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27129,curation_candidate,25263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27130,curation_candidate,25309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27131,curation_candidate,25321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27132,curation_candidate,25326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27133,curation_candidate,25347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27134,curation_candidate,25354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27135,curation_candidate,25363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27136,curation_candidate,25374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27137,curation_candidate,25395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27138,curation_candidate,25450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27139,curation_candidate,25457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27140,curation_candidate,25493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27141,curation_candidate,25521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27142,curation_candidate,25577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27143,curation_candidate,25616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27144,curation_candidate,25640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27145,curation_candidate,25651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27146,curation_candidate,25684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27147,curation_candidate,25753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27148,curation_candidate,25765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27149,curation_candidate,25766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27150,curation_candidate,25778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27151,curation_candidate,25779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27152,curation_candidate,25822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27153,curation_candidate,25867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27154,curation_candidate,25869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27155,curation_candidate,25871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27156,curation_candidate,25879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27157,curation_candidate,25980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27158,curation_candidate,26081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27159,curation_candidate,26121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27160,curation_candidate,26161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27161,curation_candidate,26214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27162,curation_candidate,26255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27163,curation_candidate,26324,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27164,curation_candidate,26409,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27165,curation_candidate,26512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27166,curation_candidate,26572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27167,curation_candidate,26600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27168,curation_candidate,26605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27169,curation_candidate,26663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27170,curation_candidate,26759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27171,curation_candidate,26774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27172,curation_candidate,26782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27173,curation_candidate,26848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27174,curation_candidate,26872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27175,curation_candidate,26877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27176,curation_candidate,26941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27177,curation_candidate,26946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27178,curation_candidate,26974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27179,curation_candidate,26977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27180,curation_candidate,27189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27181,curation_candidate,27204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27182,curation_candidate,27362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27183,curation_candidate,27369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27184,curation_candidate,27500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27185,curation_candidate,27521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27186,curation_candidate,27525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27187,curation_candidate,27534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27188,curation_candidate,27727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27189,curation_candidate,28041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27190,curation_candidate,28122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27191,curation_candidate,28449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27192,curation_candidate,28473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27193,curation_candidate,28570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27194,curation_candidate,28573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27195,curation_candidate,28857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27196,curation_candidate,29242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27197,curation_candidate,29262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27198,curation_candidate,29855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27199,curation_candidate,29985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27200,curation_candidate,30023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27201,curation_candidate,30127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27202,curation_candidate,30140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27203,curation_candidate,30142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27204,curation_candidate,30151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27205,curation_candidate,30233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27206,curation_candidate,30258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27207,curation_candidate,30263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27208,curation_candidate,30289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27209,curation_candidate,30348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27210,curation_candidate,30350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27211,curation_candidate,30449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27212,curation_candidate,30551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27213,curation_candidate,30587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27214,curation_candidate,30589,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27215,curation_candidate,30758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27216,curation_candidate,30759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27217,curation_candidate,30782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27218,curation_candidate,30810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27219,curation_candidate,30902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27220,curation_candidate,30917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27221,curation_candidate,30939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27222,curation_candidate,30962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27223,curation_candidate,31045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27224,curation_candidate,31075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27225,curation_candidate,31092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27226,curation_candidate,31097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27227,curation_candidate,31116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27228,curation_candidate,31179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27229,curation_candidate,31263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27230,curation_candidate,31482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27231,curation_candidate,31544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27232,curation_candidate,31567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27233,curation_candidate,31601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27234,curation_candidate,31622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27235,curation_candidate,31636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27236,curation_candidate,31660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27237,curation_candidate,31708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27238,curation_candidate,31745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27239,curation_candidate,31791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27240,curation_candidate,31904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27241,curation_candidate,31959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27242,curation_candidate,31964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27243,curation_candidate,32001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
27244,curation_candidate,32008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27245,curation_candidate,32015,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27246,curation_candidate,32052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27247,curation_candidate,32111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27248,curation_candidate,32127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27249,curation_candidate,32201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27250,curation_candidate,32212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27251,curation_candidate,32233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27252,curation_candidate,32248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27253,curation_candidate,32257,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27254,curation_candidate,32326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27255,curation_candidate,32353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27256,curation_candidate,32366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27257,curation_candidate,32404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27258,curation_candidate,32406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27259,curation_candidate,32419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27260,curation_candidate,32476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27261,curation_candidate,32510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27262,curation_candidate,32518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27263,curation_candidate,32583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27264,curation_candidate,32597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27265,curation_candidate,32682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27266,curation_candidate,32684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27267,curation_candidate,32688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27268,curation_candidate,32768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27269,curation_candidate,32773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27270,curation_candidate,32782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27271,curation_candidate,32812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27272,curation_candidate,32874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27273,curation_candidate,32906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27274,curation_candidate,32924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27275,curation_candidate,32930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27276,curation_candidate,32937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27277,curation_candidate,32960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27278,curation_candidate,32987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27279,curation_candidate,33041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27280,curation_candidate,33042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27281,curation_candidate,33065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27282,curation_candidate,33082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27283,curation_candidate,33119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27284,curation_candidate,33121,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27285,curation_candidate,33130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27286,curation_candidate,33137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27287,curation_candidate,33171,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27288,curation_candidate,33194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27289,curation_candidate,33199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27290,curation_candidate,33218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27291,curation_candidate,33260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27292,curation_candidate,33334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27293,curation_candidate,33396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27294,curation_candidate,33429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27295,curation_candidate,33474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27296,curation_candidate,33495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27297,curation_candidate,33498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27298,curation_candidate,33541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27299,curation_candidate,33581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27300,curation_candidate,33665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27301,curation_candidate,33688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27302,curation_candidate,33715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27303,curation_candidate,33854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27304,curation_candidate,33881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27305,curation_candidate,33890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27306,curation_candidate,33896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27307,curation_candidate,33910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27308,curation_candidate,33948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27309,curation_candidate,33959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27310,curation_candidate,33961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27311,curation_candidate,34051,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27312,curation_candidate,34059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27313,curation_candidate,34120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27314,curation_candidate,34129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27315,curation_candidate,34133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27316,curation_candidate,34172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27317,curation_candidate,34173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27318,curation_candidate,34222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27319,curation_candidate,34238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27320,curation_candidate,34252,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27321,curation_candidate,34260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27322,curation_candidate,34297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27323,curation_candidate,34309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27324,curation_candidate,34346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27325,curation_candidate,34379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27326,curation_candidate,34405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27327,curation_candidate,34441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27328,curation_candidate,34496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27329,curation_candidate,34558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27330,curation_candidate,34574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27331,curation_candidate,34579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27332,curation_candidate,34711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27333,curation_candidate,34720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27334,curation_candidate,34726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27335,curation_candidate,34735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27336,curation_candidate,34772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27337,curation_candidate,34841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27338,curation_candidate,34846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27339,curation_candidate,34861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27340,curation_candidate,34900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27341,curation_candidate,34905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27342,curation_candidate,34919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27343,curation_candidate,34964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27344,curation_candidate,35020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27345,curation_candidate,35052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27346,curation_candidate,35061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27347,curation_candidate,35068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27348,curation_candidate,35125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27349,curation_candidate,35136,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27350,curation_candidate,35156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27351,curation_candidate,35258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27352,curation_candidate,35260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27353,curation_candidate,35278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27354,curation_candidate,35326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27355,curation_candidate,35457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27356,curation_candidate,35471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27357,curation_candidate,35482,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27358,curation_candidate,35508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27359,curation_candidate,35579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27360,curation_candidate,35651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27361,curation_candidate,35710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27362,curation_candidate,35741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27363,curation_candidate,35777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27364,curation_candidate,35852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27365,curation_candidate,35862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27366,curation_candidate,35909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27367,curation_candidate,35924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27368,curation_candidate,35962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27369,curation_candidate,36020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27370,curation_candidate,36041,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27371,curation_candidate,36087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27372,curation_candidate,36088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27373,curation_candidate,36098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27374,curation_candidate,36134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27375,curation_candidate,36147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27376,curation_candidate,36164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27377,curation_candidate,36233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27378,curation_candidate,36305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27379,curation_candidate,36395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27380,curation_candidate,36400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27381,curation_candidate,36411,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27382,curation_candidate,36421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27383,curation_candidate,36483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27384,curation_candidate,36516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27385,curation_candidate,36593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27386,curation_candidate,36703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27387,curation_candidate,36966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27388,curation_candidate,37029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27389,curation_candidate,37032,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27390,curation_candidate,37079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27391,curation_candidate,37157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27392,curation_candidate,37192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27393,curation_candidate,37245,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27394,curation_candidate,37295,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27395,curation_candidate,37321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27396,curation_candidate,37362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27397,curation_candidate,37371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27398,curation_candidate,37376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27399,curation_candidate,37379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27400,curation_candidate,37403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27401,curation_candidate,37420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27402,curation_candidate,37470,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27403,curation_candidate,37496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27404,curation_candidate,37526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27405,curation_candidate,37527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27406,curation_candidate,37617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27407,curation_candidate,37618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27408,curation_candidate,37619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27409,curation_candidate,37620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27410,curation_candidate,37710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27411,curation_candidate,37742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27412,curation_candidate,37744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27413,curation_candidate,37754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27414,curation_candidate,37755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27415,curation_candidate,37851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27416,curation_candidate,37890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27417,curation_candidate,37988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27418,curation_candidate,38105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27419,curation_candidate,38129,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27420,curation_candidate,38155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27421,curation_candidate,38184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27422,curation_candidate,38202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27423,curation_candidate,38219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27424,curation_candidate,38310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27425,curation_candidate,38317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27426,curation_candidate,38318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27427,curation_candidate,16338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27428,curation_candidate,16382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27429,curation_candidate,16397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27430,curation_candidate,16440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27431,curation_candidate,16449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27432,curation_candidate,16548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27433,curation_candidate,16558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27434,curation_candidate,16632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27435,curation_candidate,16635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27436,curation_candidate,16669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27437,curation_candidate,16697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27438,curation_candidate,16709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27439,curation_candidate,16752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27440,curation_candidate,16781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27441,curation_candidate,16800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27442,curation_candidate,16801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27443,curation_candidate,16894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27444,curation_candidate,16923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27445,curation_candidate,16932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27446,curation_candidate,16941,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27447,curation_candidate,16943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27448,curation_candidate,17005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27449,curation_candidate,17007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27450,curation_candidate,17087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27451,curation_candidate,17142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27452,curation_candidate,17216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27453,curation_candidate,17226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27454,curation_candidate,17256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27455,curation_candidate,17268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27456,curation_candidate,17302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27457,curation_candidate,17348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27458,curation_candidate,17379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27459,curation_candidate,17406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27460,curation_candidate,17469,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27461,curation_candidate,17478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27462,curation_candidate,17515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27463,curation_candidate,17566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27464,curation_candidate,17567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27465,curation_candidate,17602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27466,curation_candidate,17606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27467,curation_candidate,17636,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27468,curation_candidate,17655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27469,curation_candidate,17663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27470,curation_candidate,17665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27471,curation_candidate,17675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27472,curation_candidate,17725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27473,curation_candidate,17751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27474,curation_candidate,17771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27475,curation_candidate,17778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27476,curation_candidate,17824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27477,curation_candidate,17825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27478,curation_candidate,17829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27479,curation_candidate,17834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27480,curation_candidate,17880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27481,curation_candidate,17887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27482,curation_candidate,17891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27483,curation_candidate,17902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27484,curation_candidate,17925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27485,curation_candidate,17979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27486,curation_candidate,17995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27487,curation_candidate,18002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27488,curation_candidate,18055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27489,curation_candidate,18064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27490,curation_candidate,18071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27491,curation_candidate,18083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27492,curation_candidate,18084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27493,curation_candidate,18086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27494,curation_candidate,18104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27495,curation_candidate,18127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27496,curation_candidate,18146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27497,curation_candidate,18152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27498,curation_candidate,18155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27499,curation_candidate,18161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27500,curation_candidate,18162,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27501,curation_candidate,18185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27502,curation_candidate,18225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27503,curation_candidate,18247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27504,curation_candidate,18301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27505,curation_candidate,18330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27506,curation_candidate,18389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27507,curation_candidate,18398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27508,curation_candidate,18404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27509,curation_candidate,18520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27510,curation_candidate,18530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27511,curation_candidate,18541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27512,curation_candidate,18579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27513,curation_candidate,18619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27514,curation_candidate,18809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27515,curation_candidate,18927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27516,curation_candidate,18929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27517,curation_candidate,18932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27518,curation_candidate,18961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27519,curation_candidate,19030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27520,curation_candidate,19058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27521,curation_candidate,19063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27522,curation_candidate,19078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27523,curation_candidate,19086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27524,curation_candidate,19088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27525,curation_candidate,19104,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27526,curation_candidate,19135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27527,curation_candidate,19160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27528,curation_candidate,19166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27529,curation_candidate,19235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27530,curation_candidate,19263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27531,curation_candidate,19328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27532,curation_candidate,19329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27533,curation_candidate,19336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27534,curation_candidate,19438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27535,curation_candidate,19457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27536,curation_candidate,19525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27537,curation_candidate,19578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27538,curation_candidate,19580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27539,curation_candidate,19594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27540,curation_candidate,19638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27541,curation_candidate,19639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27542,curation_candidate,19667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27543,curation_candidate,19691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27544,curation_candidate,19715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27545,curation_candidate,19736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27546,curation_candidate,19741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27547,curation_candidate,19788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27548,curation_candidate,19830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27549,curation_candidate,19862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27550,curation_candidate,19947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27551,curation_candidate,19953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27552,curation_candidate,20043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27553,curation_candidate,20059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27554,curation_candidate,20107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27555,curation_candidate,20113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27556,curation_candidate,20216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27557,curation_candidate,20277,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27558,curation_candidate,20393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27559,curation_candidate,20397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27560,curation_candidate,20399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27561,curation_candidate,20494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27562,curation_candidate,20508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27563,curation_candidate,20615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27564,curation_candidate,20629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27565,curation_candidate,20633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27566,curation_candidate,20639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27567,curation_candidate,20685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27568,curation_candidate,20705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27569,curation_candidate,20709,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27570,curation_candidate,20746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27571,curation_candidate,20771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27572,curation_candidate,20807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27573,curation_candidate,20834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27574,curation_candidate,20844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27575,curation_candidate,20861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27576,curation_candidate,20909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27577,curation_candidate,20963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27578,curation_candidate,21052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27579,curation_candidate,21087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27580,curation_candidate,21090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27581,curation_candidate,21105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27582,curation_candidate,21119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27583,curation_candidate,21149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27584,curation_candidate,21151,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27585,curation_candidate,21209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27586,curation_candidate,21237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27587,curation_candidate,21287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27588,curation_candidate,21349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27589,curation_candidate,21412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27590,curation_candidate,21422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27591,curation_candidate,21433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27592,curation_candidate,21447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27593,curation_candidate,21489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27594,curation_candidate,21525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27595,curation_candidate,21594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27596,curation_candidate,21618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27597,curation_candidate,21662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27598,curation_candidate,21675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27599,curation_candidate,21683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27600,curation_candidate,21703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27601,curation_candidate,21740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27602,curation_candidate,21763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27603,curation_candidate,21777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27604,curation_candidate,21786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27605,curation_candidate,21819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27606,curation_candidate,21822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27607,curation_candidate,21834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27608,curation_candidate,21875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
27609,curation_candidate,21918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27610,curation_candidate,21964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27611,curation_candidate,22091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27612,curation_candidate,22118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27613,curation_candidate,22124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27614,curation_candidate,22161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27615,curation_candidate,22181,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27616,curation_candidate,22186,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27617,curation_candidate,22214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27618,curation_candidate,22246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27619,curation_candidate,22319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27620,curation_candidate,22326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27621,curation_candidate,22328,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27622,curation_candidate,22366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27623,curation_candidate,22401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27624,curation_candidate,22452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27625,curation_candidate,22597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27626,curation_candidate,22701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27627,curation_candidate,22727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27628,curation_candidate,22774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27629,curation_candidate,22807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27630,curation_candidate,22862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27631,curation_candidate,22949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27632,curation_candidate,22967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27633,curation_candidate,22970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27634,curation_candidate,22992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27635,curation_candidate,22993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27636,curation_candidate,22998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27637,curation_candidate,23006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27638,curation_candidate,23011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27639,curation_candidate,23034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27640,curation_candidate,23062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27641,curation_candidate,23078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27642,curation_candidate,23158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27643,curation_candidate,23208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27644,curation_candidate,23236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27645,curation_candidate,23264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27646,curation_candidate,23284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27647,curation_candidate,23325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27648,curation_candidate,23342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27649,curation_candidate,23358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27650,curation_candidate,23449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27651,curation_candidate,23539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27652,curation_candidate,23624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27653,curation_candidate,23668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27654,curation_candidate,23669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27655,curation_candidate,23694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27656,curation_candidate,23695,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27657,curation_candidate,23740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27658,curation_candidate,23749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27659,curation_candidate,23772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27660,curation_candidate,23777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27661,curation_candidate,23789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27662,curation_candidate,23800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27663,curation_candidate,23847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27664,curation_candidate,24073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27665,curation_candidate,24117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27666,curation_candidate,24146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27667,curation_candidate,24214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27668,curation_candidate,24256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27669,curation_candidate,24260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27670,curation_candidate,24331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27671,curation_candidate,24365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27672,curation_candidate,24377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27673,curation_candidate,24415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27674,curation_candidate,24439,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27675,curation_candidate,24447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27676,curation_candidate,24488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27677,curation_candidate,24502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27678,curation_candidate,24516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27679,curation_candidate,24521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27680,curation_candidate,24569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27681,curation_candidate,24574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27682,curation_candidate,24628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27683,curation_candidate,24753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27684,curation_candidate,24869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27685,curation_candidate,24880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27686,curation_candidate,24951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27687,curation_candidate,24978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27688,curation_candidate,24984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27689,curation_candidate,25053,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27690,curation_candidate,25122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27691,curation_candidate,25127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27692,curation_candidate,25267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27693,curation_candidate,25278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27694,curation_candidate,25313,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27695,curation_candidate,25339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27696,curation_candidate,25388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
27697,curation_candidate,25438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27698,curation_candidate,25532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27699,curation_candidate,25545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27700,curation_candidate,25554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27701,curation_candidate,25564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27702,curation_candidate,25585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27703,curation_candidate,25693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27704,curation_candidate,25697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27705,curation_candidate,25733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27706,curation_candidate,25751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27707,curation_candidate,25755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27708,curation_candidate,25789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27709,curation_candidate,25800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27710,curation_candidate,25875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27711,curation_candidate,25913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27712,curation_candidate,25970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27713,curation_candidate,25974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27714,curation_candidate,26052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27715,curation_candidate,26055,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27716,curation_candidate,26179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27717,curation_candidate,26267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27718,curation_candidate,26567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27719,curation_candidate,26588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
27720,curation_candidate,26659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27721,curation_candidate,26664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27722,curation_candidate,26665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27723,curation_candidate,26669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27724,curation_candidate,26701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27725,curation_candidate,26740,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27726,curation_candidate,26763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27727,curation_candidate,26845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27728,curation_candidate,27008,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27729,curation_candidate,27086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27730,curation_candidate,27183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27731,curation_candidate,27210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27732,curation_candidate,27291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27733,curation_candidate,27300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27734,curation_candidate,27410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27735,curation_candidate,27528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27736,curation_candidate,27556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27737,curation_candidate,27641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27738,curation_candidate,27714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27739,curation_candidate,27822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27740,curation_candidate,27917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27741,curation_candidate,27932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27742,curation_candidate,27958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27743,curation_candidate,27961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27744,curation_candidate,28082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27745,curation_candidate,28154,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27746,curation_candidate,28212,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27747,curation_candidate,28225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27748,curation_candidate,28281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27749,curation_candidate,28338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27750,curation_candidate,28384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27751,curation_candidate,28404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27752,curation_candidate,28418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27753,curation_candidate,28420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27754,curation_candidate,28477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27755,curation_candidate,28545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27756,curation_candidate,28797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27757,curation_candidate,28874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27758,curation_candidate,29829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27759,curation_candidate,29836,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27760,curation_candidate,29924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27761,curation_candidate,29959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27762,curation_candidate,30043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27763,curation_candidate,30048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27764,curation_candidate,30062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27765,curation_candidate,30206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27766,curation_candidate,30230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27767,curation_candidate,30248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27768,curation_candidate,30254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27769,curation_candidate,30270,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27770,curation_candidate,30302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27771,curation_candidate,30305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27772,curation_candidate,30359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27773,curation_candidate,30370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27774,curation_candidate,30380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27775,curation_candidate,30399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27776,curation_candidate,30494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27777,curation_candidate,30539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27778,curation_candidate,30562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27779,curation_candidate,30684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27780,curation_candidate,30685,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27781,curation_candidate,30688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27782,curation_candidate,30701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27783,curation_candidate,30716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27784,curation_candidate,30752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27785,curation_candidate,30766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27786,curation_candidate,30780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27787,curation_candidate,30785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27788,curation_candidate,30809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27789,curation_candidate,30823,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27790,curation_candidate,30825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27791,curation_candidate,30826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27792,curation_candidate,30968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27793,curation_candidate,30980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27794,curation_candidate,31141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27795,curation_candidate,31183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27796,curation_candidate,31201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27797,curation_candidate,31246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27798,curation_candidate,31268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27799,curation_candidate,31422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27800,curation_candidate,31435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27801,curation_candidate,31437,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27802,curation_candidate,31446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27803,curation_candidate,31458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27804,curation_candidate,31464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27805,curation_candidate,31488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27806,curation_candidate,31537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27807,curation_candidate,31628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27808,curation_candidate,31658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27809,curation_candidate,31672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27810,curation_candidate,31715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27811,curation_candidate,31720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27812,curation_candidate,31732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27813,curation_candidate,31757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27814,curation_candidate,31760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27815,curation_candidate,31761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27816,curation_candidate,31762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27817,curation_candidate,31820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27818,curation_candidate,31883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27819,curation_candidate,31885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27820,curation_candidate,31931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27821,curation_candidate,31960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27822,curation_candidate,31981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27823,curation_candidate,31996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27824,curation_candidate,32007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27825,curation_candidate,32103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27826,curation_candidate,32108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27827,curation_candidate,32122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27828,curation_candidate,32204,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27829,curation_candidate,32253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27830,curation_candidate,32254,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27831,curation_candidate,32271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27832,curation_candidate,32311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27833,curation_candidate,32316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27834,curation_candidate,32346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27835,curation_candidate,32349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27836,curation_candidate,32374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27837,curation_candidate,32377,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27838,curation_candidate,32381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27839,curation_candidate,32408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27840,curation_candidate,32448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27841,curation_candidate,32520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27842,curation_candidate,32557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27843,curation_candidate,32578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27844,curation_candidate,32634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27845,curation_candidate,32651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27846,curation_candidate,32661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27847,curation_candidate,32687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27848,curation_candidate,32733,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27849,curation_candidate,32739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27850,curation_candidate,32751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27851,curation_candidate,32825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27852,curation_candidate,32835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27853,curation_candidate,32843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27854,curation_candidate,32849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27855,curation_candidate,32864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27856,curation_candidate,32866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27857,curation_candidate,32871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27858,curation_candidate,32878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27859,curation_candidate,32891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27860,curation_candidate,32892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27861,curation_candidate,32926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27862,curation_candidate,32944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27863,curation_candidate,32989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27864,curation_candidate,33028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27865,curation_candidate,33040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27866,curation_candidate,33049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27867,curation_candidate,33075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27868,curation_candidate,33085,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27869,curation_candidate,33134,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27870,curation_candidate,33161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27871,curation_candidate,33179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27872,curation_candidate,33207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27873,curation_candidate,33232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27874,curation_candidate,33242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27875,curation_candidate,33251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27876,curation_candidate,33258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27877,curation_candidate,33271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27878,curation_candidate,33274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27879,curation_candidate,33281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27880,curation_candidate,33282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27881,curation_candidate,33286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27882,curation_candidate,33340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27883,curation_candidate,33366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27884,curation_candidate,33373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27885,curation_candidate,33459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27886,curation_candidate,33465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27887,curation_candidate,33487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27888,curation_candidate,33489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27889,curation_candidate,33530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27890,curation_candidate,33549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27891,curation_candidate,33555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27892,curation_candidate,33572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27893,curation_candidate,33587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27894,curation_candidate,33658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27895,curation_candidate,33664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27896,curation_candidate,33699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27897,curation_candidate,33735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27898,curation_candidate,33780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27899,curation_candidate,33786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27900,curation_candidate,33849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27901,curation_candidate,33872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27902,curation_candidate,33879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27903,curation_candidate,33885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27904,curation_candidate,33903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27905,curation_candidate,33905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27906,curation_candidate,33935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27907,curation_candidate,33943,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27908,curation_candidate,33995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27909,curation_candidate,34027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27910,curation_candidate,34043,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27911,curation_candidate,34065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27912,curation_candidate,34076,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27913,curation_candidate,34083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27914,curation_candidate,34084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27915,curation_candidate,34174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27916,curation_candidate,34221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27917,curation_candidate,34242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27918,curation_candidate,34276,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27919,curation_candidate,34291,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27920,curation_candidate,34301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27921,curation_candidate,34331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27922,curation_candidate,34343,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27923,curation_candidate,34351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27924,curation_candidate,34367,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27925,curation_candidate,34389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27926,curation_candidate,34434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27927,curation_candidate,34477,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27928,curation_candidate,34500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27929,curation_candidate,34633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27930,curation_candidate,34657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27931,curation_candidate,34684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27932,curation_candidate,34751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27933,curation_candidate,34805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27934,curation_candidate,34808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27935,curation_candidate,34892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27936,curation_candidate,34893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27937,curation_candidate,34993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27938,curation_candidate,35130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27939,curation_candidate,35141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27940,curation_candidate,35165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27941,curation_candidate,35172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27942,curation_candidate,35239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27943,curation_candidate,35256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27944,curation_candidate,35283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27945,curation_candidate,35432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27946,curation_candidate,35478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27947,curation_candidate,35488,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27948,curation_candidate,35531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27949,curation_candidate,35550,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27950,curation_candidate,35567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27951,curation_candidate,35569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
27952,curation_candidate,35608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
27953,curation_candidate,35633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27954,curation_candidate,35646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27955,curation_candidate,35659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27956,curation_candidate,35665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27957,curation_candidate,35707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27958,curation_candidate,35778,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27959,curation_candidate,35834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27960,curation_candidate,35853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27961,curation_candidate,35854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27962,curation_candidate,35863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27963,curation_candidate,35930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27964,curation_candidate,35939,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27965,curation_candidate,35973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27966,curation_candidate,36014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27967,curation_candidate,36027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27968,curation_candidate,36035,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27969,curation_candidate,36061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27970,curation_candidate,36064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27971,curation_candidate,36093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27972,curation_candidate,36122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27973,curation_candidate,36127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27974,curation_candidate,36140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27975,curation_candidate,36144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27976,curation_candidate,36155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27977,curation_candidate,36172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27978,curation_candidate,36282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27979,curation_candidate,36290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27980,curation_candidate,36426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27981,curation_candidate,36454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27982,curation_candidate,36527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27983,curation_candidate,36534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27984,curation_candidate,36566,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27985,curation_candidate,36620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27986,curation_candidate,36633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27987,curation_candidate,36741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27988,curation_candidate,36765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27989,curation_candidate,36769,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27990,curation_candidate,36845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27991,curation_candidate,36908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27992,curation_candidate,37016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
27993,curation_candidate,37033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27994,curation_candidate,37050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27995,curation_candidate,37115,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
27996,curation_candidate,37306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27997,curation_candidate,37446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27998,curation_candidate,37467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
27999,curation_candidate,37590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28000,curation_candidate,37621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28001,curation_candidate,37622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28002,curation_candidate,37692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28003,curation_candidate,37721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28004,curation_candidate,37722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28005,curation_candidate,37745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28006,curation_candidate,37756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28007,curation_candidate,37786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28008,curation_candidate,37788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28009,curation_candidate,37977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28010,curation_candidate,38019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28011,curation_candidate,38020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28012,curation_candidate,38060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28013,curation_candidate,38061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28014,curation_candidate,38062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28015,curation_candidate,38063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28016,curation_candidate,38082,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28017,curation_candidate,38130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28018,curation_candidate,38131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28019,curation_candidate,38153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28020,curation_candidate,38250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28021,curation_candidate,38259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28022,curation_candidate,38261,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28023,curation_candidate,16508,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28024,curation_candidate,16599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28025,curation_candidate,16628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28026,curation_candidate,16677,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
28027,curation_candidate,16687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28028,curation_candidate,16703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28029,curation_candidate,16723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28030,curation_candidate,16725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28031,curation_candidate,16814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28032,curation_candidate,16889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28033,curation_candidate,16891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28034,curation_candidate,16902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28035,curation_candidate,16916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28036,curation_candidate,16956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28037,curation_candidate,16964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28038,curation_candidate,16983,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28039,curation_candidate,17046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28040,curation_candidate,17049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28041,curation_candidate,17164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28042,curation_candidate,17167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28043,curation_candidate,17201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28044,curation_candidate,17237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28045,curation_candidate,17286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28046,curation_candidate,17336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28047,curation_candidate,17349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28048,curation_candidate,17369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28049,curation_candidate,17431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28050,curation_candidate,17433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28051,curation_candidate,17507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28052,curation_candidate,17510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28053,curation_candidate,17526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28054,curation_candidate,17559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28055,curation_candidate,17600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28056,curation_candidate,17628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28057,curation_candidate,17646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28058,curation_candidate,17649,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28059,curation_candidate,17669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28060,curation_candidate,17727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28061,curation_candidate,17773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28062,curation_candidate,17820,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28063,curation_candidate,17849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28064,curation_candidate,17928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28065,curation_candidate,18020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28066,curation_candidate,18024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28067,curation_candidate,18058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28068,curation_candidate,18101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28069,curation_candidate,18274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28070,curation_candidate,18299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28071,curation_candidate,18312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28072,curation_candidate,18351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28073,curation_candidate,18388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28074,curation_candidate,18390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28075,curation_candidate,18507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28076,curation_candidate,18546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28077,curation_candidate,18669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28078,curation_candidate,18719,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28079,curation_candidate,18773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28080,curation_candidate,18868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28081,curation_candidate,18887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28082,curation_candidate,18888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28083,curation_candidate,18899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28084,curation_candidate,18909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28085,curation_candidate,18935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28086,curation_candidate,18945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28087,curation_candidate,18951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28088,curation_candidate,19103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28089,curation_candidate,19157,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28090,curation_candidate,19159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28091,curation_candidate,19218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28092,curation_candidate,19219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28093,curation_candidate,19230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28094,curation_candidate,19233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28095,curation_candidate,19238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28096,curation_candidate,19304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28097,curation_candidate,19317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28098,curation_candidate,19321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28099,curation_candidate,19379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28100,curation_candidate,19424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28101,curation_candidate,19454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28102,curation_candidate,19507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28103,curation_candidate,19531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28104,curation_candidate,19546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28105,curation_candidate,19562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28106,curation_candidate,19584,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28107,curation_candidate,19623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28108,curation_candidate,19631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28109,curation_candidate,19672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28110,curation_candidate,19731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28111,curation_candidate,19752,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28112,curation_candidate,19766,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28113,curation_candidate,19797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28114,curation_candidate,19855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28115,curation_candidate,19933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28116,curation_candidate,19945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28117,curation_candidate,19969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28118,curation_candidate,19979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28119,curation_candidate,20004,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28120,curation_candidate,20031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28121,curation_candidate,20062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28122,curation_candidate,20073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28123,curation_candidate,20102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28124,curation_candidate,20108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28125,curation_candidate,20158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28126,curation_candidate,20161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28127,curation_candidate,20170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28128,curation_candidate,20218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28129,curation_candidate,20251,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28130,curation_candidate,20264,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28131,curation_candidate,20329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target claim is about non-oligonucleotide therapy,2026-06-02T18:08:40+00:00
28132,curation_candidate,20348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28133,curation_candidate,20378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28134,curation_candidate,20497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28135,curation_candidate,20515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28136,curation_candidate,20522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28137,curation_candidate,20544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28138,curation_candidate,20562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28139,curation_candidate,20594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28140,curation_candidate,20598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28141,curation_candidate,20603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28142,curation_candidate,20631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28143,curation_candidate,20644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28144,curation_candidate,20670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28145,curation_candidate,20671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28146,curation_candidate,20704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28147,curation_candidate,20748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28148,curation_candidate,20753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28149,curation_candidate,20761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28150,curation_candidate,20801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28151,curation_candidate,20835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28152,curation_candidate,20854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28153,curation_candidate,20866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28154,curation_candidate,20904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28155,curation_candidate,20922,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28156,curation_candidate,20936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28157,curation_candidate,20950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28158,curation_candidate,20971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28159,curation_candidate,20986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28160,curation_candidate,21036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28161,curation_candidate,21071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28162,curation_candidate,21114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28163,curation_candidate,21120,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28164,curation_candidate,21124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28165,curation_candidate,21143,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28166,curation_candidate,21144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28167,curation_candidate,21158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28168,curation_candidate,21179,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28169,curation_candidate,21297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28170,curation_candidate,21303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28171,curation_candidate,21510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28172,curation_candidate,21548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28173,curation_candidate,21578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28174,curation_candidate,21622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28175,curation_candidate,21705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28176,curation_candidate,21734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28177,curation_candidate,21854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28178,curation_candidate,21898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28179,curation_candidate,21968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28180,curation_candidate,21989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28181,curation_candidate,22029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28182,curation_candidate,22089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28183,curation_candidate,22098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28184,curation_candidate,22103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28185,curation_candidate,22107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28186,curation_candidate,22111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28187,curation_candidate,22125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28188,curation_candidate,22128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28189,curation_candidate,22187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28190,curation_candidate,22188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28191,curation_candidate,22283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28192,curation_candidate,22306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28193,curation_candidate,22338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28194,curation_candidate,22360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28195,curation_candidate,22390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28196,curation_candidate,22413,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28197,curation_candidate,22427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28198,curation_candidate,22506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28199,curation_candidate,22536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28200,curation_candidate,22537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28201,curation_candidate,22560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28202,curation_candidate,22570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28203,curation_candidate,22632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28204,curation_candidate,22687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28205,curation_candidate,22763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28206,curation_candidate,22786,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28207,curation_candidate,22847,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28208,curation_candidate,22854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28209,curation_candidate,22881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28210,curation_candidate,22901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28211,curation_candidate,22905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28212,curation_candidate,22916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28213,curation_candidate,22951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28214,curation_candidate,22987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28215,curation_candidate,23005,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28216,curation_candidate,23022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28217,curation_candidate,23039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28218,curation_candidate,23052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28219,curation_candidate,23056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28220,curation_candidate,23086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28221,curation_candidate,23117,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28222,curation_candidate,23145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28223,curation_candidate,23296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28224,curation_candidate,23304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28225,curation_candidate,23322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28226,curation_candidate,23341,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28227,curation_candidate,23360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28228,curation_candidate,23382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28229,curation_candidate,23433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28230,curation_candidate,23737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28231,curation_candidate,23833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28232,curation_candidate,23901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28233,curation_candidate,23979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28234,curation_candidate,23985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28235,curation_candidate,23997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28236,curation_candidate,24069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28237,curation_candidate,24112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28238,curation_candidate,24114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28239,curation_candidate,24159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28240,curation_candidate,24166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28241,curation_candidate,24226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28242,curation_candidate,24231,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28243,curation_candidate,24239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28244,curation_candidate,24240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28245,curation_candidate,24246,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28246,curation_candidate,24303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28247,curation_candidate,24309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28248,curation_candidate,24329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28249,curation_candidate,24371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28250,curation_candidate,24399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28251,curation_candidate,24408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28252,curation_candidate,24428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28253,curation_candidate,24449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28254,curation_candidate,24473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28255,curation_candidate,24476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28256,curation_candidate,24478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28257,curation_candidate,24490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28258,curation_candidate,24567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28259,curation_candidate,24596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28260,curation_candidate,24694,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28261,curation_candidate,24725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28262,curation_candidate,24734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28263,curation_candidate,24757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28264,curation_candidate,24761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28265,curation_candidate,24815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28266,curation_candidate,24824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28267,curation_candidate,24833,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28268,curation_candidate,24865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28269,curation_candidate,24882,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28270,curation_candidate,25006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28271,curation_candidate,25007,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28272,curation_candidate,25024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28273,curation_candidate,25038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28274,curation_candidate,25050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28275,curation_candidate,25107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28276,curation_candidate,25170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28277,curation_candidate,25233,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28278,curation_candidate,25234,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28279,curation_candidate,25308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28280,curation_candidate,25337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28281,curation_candidate,25389,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28282,curation_candidate,25425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28283,curation_candidate,25429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28284,curation_candidate,25510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28285,curation_candidate,25513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28286,curation_candidate,25553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28287,curation_candidate,25558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28288,curation_candidate,25581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28289,curation_candidate,25621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28290,curation_candidate,25718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28291,curation_candidate,25754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28292,curation_candidate,25767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28293,curation_candidate,25863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28294,curation_candidate,25901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28295,curation_candidate,25940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28296,curation_candidate,26021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28297,curation_candidate,26034,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28298,curation_candidate,26236,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28299,curation_candidate,26529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28300,curation_candidate,26587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28301,curation_candidate,26594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28302,curation_candidate,26638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28303,curation_candidate,26651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28304,curation_candidate,26875,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28305,curation_candidate,26880,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28306,curation_candidate,26884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28307,curation_candidate,27110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28308,curation_candidate,27458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28309,curation_candidate,27569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28310,curation_candidate,27606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28311,curation_candidate,27620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28312,curation_candidate,27667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28313,curation_candidate,27756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28314,curation_candidate,27835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28315,curation_candidate,27858,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28316,curation_candidate,27911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28317,curation_candidate,27923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28318,curation_candidate,28011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28319,curation_candidate,28048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28320,curation_candidate,28059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28321,curation_candidate,28083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28322,curation_candidate,28141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28323,curation_candidate,28168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28324,curation_candidate,28248,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28325,curation_candidate,28385,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28326,curation_candidate,28397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28327,curation_candidate,28483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28328,curation_candidate,28504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28329,curation_candidate,28552,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28330,curation_candidate,28569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28331,curation_candidate,28604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28332,curation_candidate,28773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28333,curation_candidate,28905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28334,curation_candidate,28925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28335,curation_candidate,28990,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28336,curation_candidate,29256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28337,curation_candidate,29623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28338,curation_candidate,29859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28339,curation_candidate,29910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28340,curation_candidate,29968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28341,curation_candidate,30025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28342,curation_candidate,30065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28343,curation_candidate,30074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28344,curation_candidate,30097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28345,curation_candidate,30126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28346,curation_candidate,30128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28347,curation_candidate,30130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28348,curation_candidate,30168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28349,curation_candidate,30190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28350,curation_candidate,30203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28351,curation_candidate,30215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28352,curation_candidate,30220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28353,curation_candidate,30232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
28354,curation_candidate,30315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28355,curation_candidate,30323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28356,curation_candidate,30340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28357,curation_candidate,30374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28358,curation_candidate,30386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28359,curation_candidate,30417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28360,curation_candidate,30483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28361,curation_candidate,30560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28362,curation_candidate,30573,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28363,curation_candidate,30577,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28364,curation_candidate,30580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28365,curation_candidate,30581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28366,curation_candidate,30727,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28367,curation_candidate,30818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28368,curation_candidate,30828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28369,curation_candidate,30839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28370,curation_candidate,30854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28371,curation_candidate,30862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28372,curation_candidate,30952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28373,curation_candidate,30979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28374,curation_candidate,31031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28375,curation_candidate,31033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28376,curation_candidate,31046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28377,curation_candidate,31109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28378,curation_candidate,31165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28379,curation_candidate,31219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28380,curation_candidate,31247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28381,curation_candidate,31265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28382,curation_candidate,31281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28383,curation_candidate,31286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28384,curation_candidate,31305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28385,curation_candidate,31401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28386,curation_candidate,31404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28387,curation_candidate,31441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28388,curation_candidate,31454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28389,curation_candidate,31460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28390,curation_candidate,31525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28391,curation_candidate,31543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28392,curation_candidate,31548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28393,curation_candidate,31591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28394,curation_candidate,31642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28395,curation_candidate,31689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28396,curation_candidate,31793,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28397,curation_candidate,31807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28398,curation_candidate,31814,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28399,curation_candidate,31821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28400,curation_candidate,31834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28401,curation_candidate,31907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28402,curation_candidate,31920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28403,curation_candidate,31934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28404,curation_candidate,31935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28405,curation_candidate,31970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28406,curation_candidate,32025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28407,curation_candidate,32074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28408,curation_candidate,32077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28409,curation_candidate,32096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28410,curation_candidate,32097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28411,curation_candidate,32130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28412,curation_candidate,32144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28413,curation_candidate,32155,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28414,curation_candidate,32165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28415,curation_candidate,32175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28416,curation_candidate,32206,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28417,curation_candidate,32300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28418,curation_candidate,32327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28419,curation_candidate,32433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28420,curation_candidate,32500,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28421,curation_candidate,32521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28422,curation_candidate,32558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28423,curation_candidate,32571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28424,curation_candidate,32647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28425,curation_candidate,32703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28426,curation_candidate,32736,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28427,curation_candidate,32779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28428,curation_candidate,32845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28429,curation_candidate,32903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28430,curation_candidate,32913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28431,curation_candidate,32914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28432,curation_candidate,32925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28433,curation_candidate,32976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28434,curation_candidate,33020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28435,curation_candidate,33039,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28436,curation_candidate,33079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28437,curation_candidate,33185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28438,curation_candidate,33346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28439,curation_candidate,33356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28440,curation_candidate,33360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28441,curation_candidate,33406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28442,curation_candidate,33442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28443,curation_candidate,33446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28444,curation_candidate,33447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28445,curation_candidate,33460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28446,curation_candidate,33464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28447,curation_candidate,33497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28448,curation_candidate,33531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28449,curation_candidate,33579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28450,curation_candidate,33599,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28451,curation_candidate,33607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28452,curation_candidate,33617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28453,curation_candidate,33631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28454,curation_candidate,33634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28455,curation_candidate,33692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28456,curation_candidate,33801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28457,curation_candidate,33808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28458,curation_candidate,33869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28459,curation_candidate,33874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28460,curation_candidate,33892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28461,curation_candidate,33914,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28462,curation_candidate,33947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28463,curation_candidate,34009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28464,curation_candidate,34012,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28465,curation_candidate,34054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28466,curation_candidate,34077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28467,curation_candidate,34089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28468,curation_candidate,34108,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28469,curation_candidate,34122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28470,curation_candidate,34161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28471,curation_candidate,34183,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28472,curation_candidate,34239,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28473,curation_candidate,34243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: non-therapeutic oligonucleotide method/tool source,2026-06-02T18:08:40+00:00
28474,curation_candidate,34375,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28475,curation_candidate,34383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28476,curation_candidate,34403,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28477,curation_candidate,34467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28478,curation_candidate,34472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28479,curation_candidate,34478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28480,curation_candidate,34502,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28481,curation_candidate,34505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28482,curation_candidate,34578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28483,curation_candidate,34590,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28484,curation_candidate,34619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28485,curation_candidate,34626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28486,curation_candidate,34656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28487,curation_candidate,34690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28488,curation_candidate,34773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28489,curation_candidate,34816,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28490,curation_candidate,34849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28491,curation_candidate,34855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28492,curation_candidate,34869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28493,curation_candidate,34948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28494,curation_candidate,35131,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28495,curation_candidate,35137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28496,curation_candidate,35146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28497,curation_candidate,35300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28498,curation_candidate,35303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28499,curation_candidate,35349,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28500,curation_candidate,35421,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28501,curation_candidate,35424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28502,curation_candidate,35442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28503,curation_candidate,35526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28504,curation_candidate,35532,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28505,curation_candidate,35588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28506,curation_candidate,35617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28507,curation_candidate,35641,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28508,curation_candidate,35696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28509,curation_candidate,35746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28510,curation_candidate,35819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28511,curation_candidate,35883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28512,curation_candidate,35905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28513,curation_candidate,35916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28514,curation_candidate,35931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28515,curation_candidate,35934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28516,curation_candidate,35940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28517,curation_candidate,35974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28518,curation_candidate,35986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28519,curation_candidate,36003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28520,curation_candidate,36090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28521,curation_candidate,36101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28522,curation_candidate,36139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28523,curation_candidate,36165,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28524,curation_candidate,36166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28525,curation_candidate,36188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28526,curation_candidate,36325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28527,curation_candidate,36353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28528,curation_candidate,36387,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28529,curation_candidate,36390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28530,curation_candidate,36518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28531,curation_candidate,36528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28532,curation_candidate,36539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28533,curation_candidate,36607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28534,curation_candidate,36619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28535,curation_candidate,36854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28536,curation_candidate,37094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28537,curation_candidate,37099,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28538,curation_candidate,37113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28539,curation_candidate,37224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28540,curation_candidate,37260,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28541,curation_candidate,37275,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28542,curation_candidate,37305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28543,curation_candidate,37336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28544,curation_candidate,37394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28545,curation_candidate,37427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28546,curation_candidate,37455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28547,curation_candidate,37456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28548,curation_candidate,37471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28549,curation_candidate,37476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28550,curation_candidate,37493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28551,curation_candidate,37494,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28552,curation_candidate,37497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28553,curation_candidate,37498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28554,curation_candidate,37528,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28555,curation_candidate,37529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28556,curation_candidate,37623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28557,curation_candidate,37651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28558,curation_candidate,37684,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28559,curation_candidate,37702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28560,curation_candidate,37723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28561,curation_candidate,37757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28562,curation_candidate,37787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28563,curation_candidate,37789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28564,curation_candidate,37812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28565,curation_candidate,37828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28566,curation_candidate,37841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28567,curation_candidate,37891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28568,curation_candidate,37892,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28569,curation_candidate,37917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28570,curation_candidate,37918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28571,curation_candidate,37948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28572,curation_candidate,37965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28573,curation_candidate,37974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28574,curation_candidate,38064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28575,curation_candidate,38132,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28576,curation_candidate,38137,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28577,curation_candidate,38144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28578,curation_candidate,38166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28579,curation_candidate,38167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28580,curation_candidate,38168,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28581,curation_candidate,38201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28582,curation_candidate,38302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28583,curation_candidate,16340,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28584,curation_candidate,16400,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28585,curation_candidate,16485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28586,curation_candidate,16520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28587,curation_candidate,16634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28588,curation_candidate,16654,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28589,curation_candidate,16711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28590,curation_candidate,16782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28591,curation_candidate,16791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28592,curation_candidate,16815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28593,curation_candidate,16837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28594,curation_candidate,16848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28595,curation_candidate,16851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28596,curation_candidate,16925,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28597,curation_candidate,16952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28598,curation_candidate,16954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28599,curation_candidate,17019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28600,curation_candidate,17074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28601,curation_candidate,17159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28602,curation_candidate,17163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28603,curation_candidate,17210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28604,curation_candidate,17250,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28605,curation_candidate,17271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28606,curation_candidate,17297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28607,curation_candidate,17325,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28608,curation_candidate,17337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28609,curation_candidate,17355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28610,curation_candidate,17358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28611,curation_candidate,17366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28612,curation_candidate,17395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28613,curation_candidate,17435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28614,curation_candidate,17513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28615,curation_candidate,17525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28616,curation_candidate,17537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28617,curation_candidate,17563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28618,curation_candidate,17737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28619,curation_candidate,17828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28620,curation_candidate,17855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28621,curation_candidate,17866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28622,curation_candidate,17889,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28623,curation_candidate,17908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
28624,curation_candidate,17916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28625,curation_candidate,17936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28626,curation_candidate,17966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28627,curation_candidate,18029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28628,curation_candidate,18048,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28629,curation_candidate,18052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28630,curation_candidate,18056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28631,curation_candidate,18062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28632,curation_candidate,18069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28633,curation_candidate,18091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28634,curation_candidate,18135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28635,curation_candidate,18196,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28636,curation_candidate,18209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28637,curation_candidate,18223,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28638,curation_candidate,18253,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28639,curation_candidate,18266,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28640,curation_candidate,18331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28641,curation_candidate,18358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28642,curation_candidate,18360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28643,curation_candidate,18395,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28644,curation_candidate,18418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28645,curation_candidate,18436,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28646,curation_candidate,18438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28647,curation_candidate,18440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28648,curation_candidate,18479,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28649,curation_candidate,18563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28650,curation_candidate,18571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28651,curation_candidate,18609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28652,curation_candidate,18633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28653,curation_candidate,18655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28654,curation_candidate,18710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28655,curation_candidate,18722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28656,curation_candidate,18739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28657,curation_candidate,18754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28658,curation_candidate,18755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28659,curation_candidate,18756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28660,curation_candidate,18837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28661,curation_candidate,18874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28662,curation_candidate,18944,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28663,curation_candidate,19040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28664,curation_candidate,19071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28665,curation_candidate,19142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28666,curation_candidate,19163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28667,curation_candidate,19278,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28668,curation_candidate,19301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28669,curation_candidate,19334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28670,curation_candidate,19458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28671,curation_candidate,19483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28672,curation_candidate,19530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
28673,curation_candidate,19557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28674,curation_candidate,19622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28675,curation_candidate,19689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28676,curation_candidate,19693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28677,curation_candidate,19815,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28678,curation_candidate,19818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28679,curation_candidate,19918,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28680,curation_candidate,19950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28681,curation_candidate,19976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28682,curation_candidate,19993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28683,curation_candidate,20057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28684,curation_candidate,20125,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28685,curation_candidate,20152,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28686,curation_candidate,20159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: abstract does not report an off-target result or assay,2026-06-02T18:08:40+00:00
28687,curation_candidate,20177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28688,curation_candidate,20194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28689,curation_candidate,20224,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28690,curation_candidate,20226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28691,curation_candidate,20281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28692,curation_candidate,20330,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28693,curation_candidate,20452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28694,curation_candidate,20455,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28695,curation_candidate,20507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28696,curation_candidate,20553,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28697,curation_candidate,20608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28698,curation_candidate,20627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28699,curation_candidate,20707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28700,curation_candidate,20739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28701,curation_candidate,20759,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28702,curation_candidate,20838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28703,curation_candidate,20855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28704,curation_candidate,20881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28705,curation_candidate,21081,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28706,curation_candidate,21097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28707,curation_candidate,21118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28708,curation_candidate,21139,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28709,curation_candidate,21199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28710,curation_candidate,21360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28711,curation_candidate,21368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28712,curation_candidate,21495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28713,curation_candidate,21563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28714,curation_candidate,21583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28715,curation_candidate,21615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28716,curation_candidate,21775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28717,curation_candidate,21844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28718,curation_candidate,21894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28719,curation_candidate,22021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28720,curation_candidate,22028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28721,curation_candidate,22037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28722,curation_candidate,22119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28723,curation_candidate,22150,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28724,curation_candidate,22222,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28725,curation_candidate,22265,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28726,curation_candidate,22273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28727,curation_candidate,22293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28728,curation_candidate,22298,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28729,curation_candidate,22308,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28730,curation_candidate,22348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28731,curation_candidate,22368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28732,curation_candidate,22372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28733,curation_candidate,22392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28734,curation_candidate,22474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28735,curation_candidate,22507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28736,curation_candidate,22625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28737,curation_candidate,22698,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28738,curation_candidate,22728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28739,curation_candidate,22745,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28740,curation_candidate,22810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28741,curation_candidate,22952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28742,curation_candidate,22961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28743,curation_candidate,22968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28744,curation_candidate,22995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28745,curation_candidate,23044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28746,curation_candidate,23090,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28747,curation_candidate,23141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28748,curation_candidate,23163,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28749,curation_candidate,23164,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28750,curation_candidate,23178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28751,curation_candidate,23230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28752,curation_candidate,23267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28753,curation_candidate,23285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28754,curation_candidate,23357,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28755,curation_candidate,23373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28756,curation_candidate,23467,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28757,curation_candidate,23510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28758,curation_candidate,23521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28759,curation_candidate,23545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28760,curation_candidate,23580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28761,curation_candidate,23583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28762,curation_candidate,23602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28763,curation_candidate,23631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28764,curation_candidate,23663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28765,curation_candidate,23673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28766,curation_candidate,23691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28767,curation_candidate,23774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28768,curation_candidate,23792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28769,curation_candidate,23822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28770,curation_candidate,23893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28771,curation_candidate,23904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28772,curation_candidate,23912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28773,curation_candidate,23956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28774,curation_candidate,23960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28775,curation_candidate,23981,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28776,curation_candidate,23989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28777,curation_candidate,24045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28778,curation_candidate,24071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28779,curation_candidate,24089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28780,curation_candidate,24142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28781,curation_candidate,24167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28782,curation_candidate,24242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28783,curation_candidate,24274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28784,curation_candidate,24315,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28785,curation_candidate,24394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28786,curation_candidate,24492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28787,curation_candidate,24509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28788,curation_candidate,24551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28789,curation_candidate,24570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28790,curation_candidate,24618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28791,curation_candidate,24661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28792,curation_candidate,24691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28793,curation_candidate,24744,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28794,curation_candidate,24765,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28795,curation_candidate,24771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28796,curation_candidate,24782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28797,curation_candidate,24783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28798,curation_candidate,24937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28799,curation_candidate,24955,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28800,curation_candidate,24964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28801,curation_candidate,25054,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28802,curation_candidate,25188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28803,curation_candidate,25193,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28804,curation_candidate,25274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28805,curation_candidate,25280,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28806,curation_candidate,25322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28807,curation_candidate,25323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28808,curation_candidate,25368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28809,curation_candidate,25404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28810,curation_candidate,25416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28811,curation_candidate,25428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28812,curation_candidate,25444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28813,curation_candidate,25451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28814,curation_candidate,25603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28815,curation_candidate,25614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28816,curation_candidate,25643,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28817,curation_candidate,25837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28818,curation_candidate,25907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28819,curation_candidate,26178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28820,curation_candidate,26244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28821,curation_candidate,26369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28822,curation_candidate,26507,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28823,curation_candidate,26700,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28824,curation_candidate,26741,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28825,curation_candidate,26961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28826,curation_candidate,26987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28827,curation_candidate,27088,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28828,curation_candidate,27146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28829,curation_candidate,27158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28830,curation_candidate,27598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28831,curation_candidate,27938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28832,curation_candidate,28118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target mention is not supported by primary analysis,2026-06-02T18:08:40+00:00
28833,curation_candidate,28262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28834,curation_candidate,28263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28835,curation_candidate,28303,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28836,curation_candidate,28342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28837,curation_candidate,28360,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28838,curation_candidate,28408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28839,curation_candidate,28591,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28840,curation_candidate,28715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28841,curation_candidate,28758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28842,curation_candidate,28887,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28843,curation_candidate,28928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28844,curation_candidate,29156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28845,curation_candidate,29773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28846,curation_candidate,29785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28847,curation_candidate,29797,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28848,curation_candidate,29861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28849,curation_candidate,29896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28850,curation_candidate,29933,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28851,curation_candidate,29935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28852,curation_candidate,29954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28853,curation_candidate,29965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28854,curation_candidate,29967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28855,curation_candidate,29977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28856,curation_candidate,29993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28857,curation_candidate,30013,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28858,curation_candidate,30017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28859,curation_candidate,30178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28860,curation_candidate,30218,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28861,curation_candidate,30229,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28862,curation_candidate,30274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28863,curation_candidate,30286,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28864,curation_candidate,30311,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28865,curation_candidate,30335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28866,curation_candidate,30351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28867,curation_candidate,30363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28868,curation_candidate,30505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28869,curation_candidate,30512,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28870,curation_candidate,30533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28871,curation_candidate,30574,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28872,curation_candidate,30615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28873,curation_candidate,30621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28874,curation_candidate,30646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28875,curation_candidate,30647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28876,curation_candidate,30657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28877,curation_candidate,30679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28878,curation_candidate,30686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28879,curation_candidate,30699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28880,curation_candidate,30721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28881,curation_candidate,30728,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28882,curation_candidate,30763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28883,curation_candidate,30811,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28884,curation_candidate,30848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28885,curation_candidate,30855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28886,curation_candidate,30894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28887,curation_candidate,30942,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28888,curation_candidate,30957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28889,curation_candidate,30964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28890,curation_candidate,30970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28891,curation_candidate,31006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28892,curation_candidate,31019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28893,curation_candidate,31061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28894,curation_candidate,31073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28895,curation_candidate,31102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28896,curation_candidate,31146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28897,curation_candidate,31156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28898,curation_candidate,31160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28899,curation_candidate,31177,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28900,curation_candidate,31197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28901,curation_candidate,31207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28902,curation_candidate,31210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28903,curation_candidate,31225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28904,curation_candidate,31238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28905,curation_candidate,31244,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28906,curation_candidate,31287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28907,curation_candidate,31297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28908,curation_candidate,31310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28909,curation_candidate,31362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28910,curation_candidate,31371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28911,curation_candidate,31405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28912,curation_candidate,31412,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28913,curation_candidate,31434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28914,curation_candidate,31444,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28915,curation_candidate,31445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28916,curation_candidate,31562,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28917,curation_candidate,31578,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28918,curation_candidate,31596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28919,curation_candidate,31600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28920,curation_candidate,31605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28921,curation_candidate,31623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28922,curation_candidate,31625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28923,curation_candidate,31632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28924,curation_candidate,31657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28925,curation_candidate,31725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28926,curation_candidate,31750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28927,curation_candidate,31755,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28928,curation_candidate,31774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28929,curation_candidate,31800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28930,curation_candidate,31805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28931,curation_candidate,31808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28932,curation_candidate,31829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28933,curation_candidate,31842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28934,curation_candidate,31850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28935,curation_candidate,31851,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28936,curation_candidate,31899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28937,curation_candidate,31923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28938,curation_candidate,31924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28939,curation_candidate,31952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28940,curation_candidate,31953,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28941,curation_candidate,31963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28942,curation_candidate,31971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28943,curation_candidate,31989,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28944,curation_candidate,32000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28945,curation_candidate,32006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28946,curation_candidate,32016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: no explicit molecule, target, or cohort for verified release evidence",2026-06-02T18:08:40+00:00
28947,curation_candidate,32019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28948,curation_candidate,32045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28949,curation_candidate,32047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28950,curation_candidate,32078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28951,curation_candidate,32091,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28952,curation_candidate,32105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28953,curation_candidate,32110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28954,curation_candidate,32119,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28955,curation_candidate,32128,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28956,curation_candidate,32138,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28957,curation_candidate,32142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28958,curation_candidate,32147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28959,curation_candidate,32158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28960,curation_candidate,32220,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28961,curation_candidate,32221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28962,curation_candidate,32237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28963,curation_candidate,32242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28964,curation_candidate,32249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28965,curation_candidate,32255,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28966,curation_candidate,32267,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28967,curation_candidate,32283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28968,curation_candidate,32284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28969,curation_candidate,32296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28970,curation_candidate,32299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28971,curation_candidate,32323,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28972,curation_candidate,32345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28973,curation_candidate,32362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28974,curation_candidate,32370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28975,curation_candidate,32396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28976,curation_candidate,32399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28977,curation_candidate,32417,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28978,curation_candidate,32420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28979,curation_candidate,32424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28980,curation_candidate,32445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28981,curation_candidate,32473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28982,curation_candidate,32485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28983,curation_candidate,32516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28984,curation_candidate,32529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28985,curation_candidate,32545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: delivery/PK source without title-level off-target assay,2026-06-02T18:08:40+00:00
28986,curation_candidate,32585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28987,curation_candidate,32600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28988,curation_candidate,32627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28989,curation_candidate,32691,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28990,curation_candidate,32693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28991,curation_candidate,32704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28992,curation_candidate,32708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28993,curation_candidate,32732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28994,curation_candidate,32743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28995,curation_candidate,32780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28996,curation_candidate,32785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
28997,curation_candidate,32806,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T18:08:40+00:00
28998,curation_candidate,32885,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
28999,curation_candidate,32893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29000,curation_candidate,32897,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29001,curation_candidate,32902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29002,curation_candidate,32912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29003,curation_candidate,32928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29004,curation_candidate,32938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29005,curation_candidate,32940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29006,curation_candidate,32947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29007,curation_candidate,32958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29008,curation_candidate,32961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29009,curation_candidate,32965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29010,curation_candidate,32967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29011,curation_candidate,33044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29012,curation_candidate,33058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29013,curation_candidate,33102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29014,curation_candidate,33122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29015,curation_candidate,33123,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29016,curation_candidate,33124,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29017,curation_candidate,33140,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29018,curation_candidate,33184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29019,curation_candidate,33219,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29020,curation_candidate,33284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29021,curation_candidate,33335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29022,curation_candidate,33351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T18:08:40+00:00
29023,curation_candidate,33362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: source text lacks concrete off-target evidence,2026-06-02T18:08:40+00:00
29024,offtarget_evidence,331,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for F7-1 siRNA.,2026-06-02T20:47:17+00:00
29025,offtarget_evidence,332,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for DNA-modified siRNA.,2026-06-02T20:47:17+00:00
29026,offtarget_evidence,333,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for ATXN3-AON.,2026-06-02T20:47:17+00:00
29027,offtarget_evidence,334,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for modified duplex.,2026-06-02T20:47:17+00:00
29028,offtarget_evidence,335,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for E6 siRNA.,2026-06-02T20:47:17+00:00
29029,offtarget_evidence,336,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for sli-siRNA.,2026-06-02T20:47:17+00:00
29030,offtarget_evidence,337,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for UNA-T siRNA.,2026-06-02T20:47:17+00:00
29031,offtarget_evidence,338,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for siCD46 siRNA.,2026-06-02T20:47:17+00:00
29032,offtarget_evidence,339,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for BTK siRNA.,2026-06-02T20:47:17+00:00
29033,offtarget_evidence,340,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for GR18-3 ASO.,2026-06-02T20:47:17+00:00
29034,offtarget_evidence,341,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for PCSK9 siRNA.,2026-06-02T20:47:17+00:00
29035,offtarget_evidence,342,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for ss-siRNA.,2026-06-02T20:47:17+00:00
29036,offtarget_evidence,343,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for SOD-1.,2026-06-02T20:47:17+00:00
29037,offtarget_evidence,344,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for VIR-2218.,2026-06-02T20:47:17+00:00
29038,offtarget_evidence,345,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siRNA-5.,2026-06-02T20:47:17+00:00
29039,offtarget_evidence,346,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for LNA-PS ASO.,2026-06-02T20:47:17+00:00
29040,offtarget_evidence,347,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for SCR ASO.,2026-06-02T20:47:17+00:00
29041,offtarget_evidence,348,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for siRNA-604.,2026-06-02T20:47:17+00:00
29042,offtarget_evidence,349,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for DCA-siRNA.,2026-06-02T20:47:17+00:00
29043,offtarget_evidence,350,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for THP-1.,2026-06-02T20:47:17+00:00
29044,offtarget_evidence,351,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siVIM-270.,2026-06-02T20:47:17+00:00
29045,offtarget_evidence,352,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for RAB18.,2026-06-02T20:47:17+00:00
29046,offtarget_evidence,353,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for SOD1.,2026-06-02T20:47:17+00:00
29047,offtarget_evidence,354,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for STAT3.,2026-06-02T20:47:17+00:00
29048,offtarget_evidence,355,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for DM1.,2026-06-02T20:47:17+00:00
29049,offtarget_evidence,356,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for 199-401.,2026-06-02T20:47:17+00:00
29050,offtarget_evidence,357,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for RILP shRNA.,2026-06-02T20:47:17+00:00
29051,offtarget_evidence,358,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siNT-1.,2026-06-02T20:47:17+00:00
29052,offtarget_evidence,359,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siVwf5.,2026-06-02T20:47:17+00:00
29053,offtarget_evidence,360,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for shS1.,2026-06-02T20:47:17+00:00
29054,offtarget_evidence,361,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for siCtle1.,2026-06-02T20:47:17+00:00
29055,offtarget_evidence,362,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for 70 siRNA.,2026-06-02T20:47:17+00:00
29056,offtarget_evidence,363,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for siSdf1.,2026-06-02T20:47:17+00:00
29057,offtarget_evidence,364,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for siCdc2.,2026-06-02T20:47:17+00:00
29058,offtarget_evidence,365,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for RIsearch2.,2026-06-02T20:47:17+00:00
29059,offtarget_evidence,366,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for shR6.,2026-06-02T20:47:17+00:00
29060,offtarget_evidence,367,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for CDCA7L shRNA.,2026-06-02T20:47:17+00:00
29061,offtarget_evidence,368,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for 27-32.,2026-06-02T20:47:17+00:00
29062,offtarget_evidence,369,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for AF9.,2026-06-02T20:47:17+00:00
29063,offtarget_evidence,370,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for 60 siRNA.,2026-06-02T20:47:17+00:00
29064,offtarget_evidence,371,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for DNA-modified siRNA.,2026-06-02T20:47:17+00:00
29065,offtarget_evidence,372,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for HoxA1.,2026-06-02T20:47:17+00:00
29066,offtarget_evidence,373,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for 353 siRNA.,2026-06-02T20:47:17+00:00
29067,offtarget_evidence,374,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for IDH1 siRNA.,2026-06-02T20:47:17+00:00
29068,offtarget_evidence,375,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for ss-siRNA.,2026-06-02T20:47:17+00:00
29069,offtarget_evidence,376,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for siR-04.,2026-06-02T20:47:17+00:00
29070,offtarget_evidence,377,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for si2A-AF555.,2026-06-02T20:47:17+00:00
29071,offtarget_evidence,378,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for H1-shRNA.,2026-06-02T20:47:17+00:00
29072,offtarget_evidence,379,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for EIF-5A-siRNA.,2026-06-02T20:47:17+00:00
29073,offtarget_evidence,380,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for shRNA18.,2026-06-02T20:47:17+00:00
29074,offtarget_evidence,381,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for 000 siRNA.,2026-06-02T20:47:17+00:00
29075,offtarget_evidence,382,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for TGFBR2.,2026-06-02T20:47:17+00:00
29076,offtarget_evidence,383,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siEGFP1.,2026-06-02T20:47:17+00:00
29077,offtarget_evidence,384,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for Ago2; Ago1.,2026-06-02T20:47:17+00:00
29078,offtarget_evidence,385,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for MBD6 siRNA.,2026-06-02T20:47:17+00:00
29079,offtarget_evidence,386,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for TNFR1.,2026-06-02T20:47:17+00:00
29080,offtarget_evidence,387,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for siGL3.,2026-06-02T20:47:17+00:00
29081,offtarget_evidence,388,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for 14-8 siRNA.,2026-06-02T20:47:17+00:00
29082,offtarget_evidence,389,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for 10-5.,2026-06-02T20:47:17+00:00
29083,offtarget_evidence,390,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for TS1-ASO.,2026-06-02T20:47:17+00:00
29084,offtarget_evidence,391,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for S10-1.,2026-06-02T20:47:17+00:00
29085,offtarget_evidence,392,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for LNA ASO.,2026-06-02T20:47:17+00:00
29086,offtarget_evidence,393,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for SNA2-ASO.,2026-06-02T20:47:17+00:00
29087,offtarget_evidence,394,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for TMEM16a.,2026-06-02T20:47:17+00:00
29088,offtarget_evidence,395,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for JQ1-ASO.,2026-06-02T20:47:17+00:00
29089,offtarget_evidence,396,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for SNORA13.,2026-06-02T20:47:17+00:00
29090,offtarget_evidence,397,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for SARM1.,2026-06-02T20:47:17+00:00
29091,offtarget_evidence,398,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for GNAO1-neurodevelopmental.,2026-06-02T20:47:17+00:00
29092,offtarget_evidence,399,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for SSR-5.,2026-06-02T20:47:17+00:00
29093,offtarget_evidence,400,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for APOE-1 ASO.,2026-06-02T20:47:17+00:00
29094,offtarget_evidence,401,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for MeCP2.,2026-06-02T20:47:17+00:00
29095,offtarget_evidence,402,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for L858R ASO.,2026-06-02T20:47:17+00:00
29096,offtarget_evidence,403,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for STAT6-targeting.,2026-06-02T20:47:17+00:00
29097,offtarget_evidence,404,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for PC-3.,2026-06-02T20:47:17+00:00
29098,offtarget_evidence,405,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for STAT6.,2026-06-02T20:47:17+00:00
29099,offtarget_evidence,406,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for nusinersen.,2026-06-02T20:47:17+00:00
29100,offtarget_evidence,407,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for PS ASO.,2026-06-02T20:47:17+00:00
29101,offtarget_evidence,408,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for T0 ASO.,2026-06-02T20:47:17+00:00
29102,offtarget_evidence,409,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for STAT3.,2026-06-02T20:47:17+00:00
29103,offtarget_evidence,410,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for TGFBR2-A.,2026-06-02T20:47:17+00:00
29104,offtarget_evidence,411,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for PS-ASO.,2026-06-02T20:47:17+00:00
29105,offtarget_evidence,412,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for PS ASO.,2026-06-02T20:47:17+00:00
29106,offtarget_evidence,413,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for 45-47.,2026-06-02T20:47:17+00:00
29107,offtarget_evidence,414,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for CD-1.,2026-06-02T20:47:17+00:00
29108,offtarget_evidence,415,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for WRN-108.,2026-06-02T20:47:17+00:00
29109,offtarget_evidence,416,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for KCNT1.,2026-06-02T20:47:17+00:00
29110,offtarget_evidence,417,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for HIV-1.,2026-06-02T20:47:17+00:00
29111,offtarget_evidence,418,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for PS-ASO.,2026-06-02T20:47:17+00:00
29112,offtarget_evidence,419,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for BLOC1S1.,2026-06-02T20:47:17+00:00
29113,offtarget_evidence,420,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for siRNA-3.,2026-06-02T20:47:17+00:00
29114,offtarget_evidence,421,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for DFNA2.,2026-06-02T20:47:17+00:00
29115,offtarget_evidence,422,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for NRAS ASO.,2026-06-02T20:47:17+00:00
29116,offtarget_evidence,423,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for ASO-1570.,2026-06-02T20:47:17+00:00
29117,offtarget_evidence,424,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for 1504-818.,2026-06-02T20:47:17+00:00
29118,offtarget_evidence,425,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for MECP2.,2026-06-02T20:47:17+00:00
29119,offtarget_evidence,426,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for CALM2 ASO.,2026-06-02T20:47:17+00:00
29120,offtarget_evidence,427,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for siTie2.,2026-06-02T20:47:17+00:00
29121,offtarget_evidence,428,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for IGF-1.,2026-06-02T20:47:17+00:00
29122,offtarget_evidence,429,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for ABCA4.,2026-06-02T20:47:17+00:00
29123,offtarget_evidence,430,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for nusinersen.,2026-06-02T20:47:17+00:00
29124,offtarget_evidence,431,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for PRNP ASO.,2026-06-02T20:47:17+00:00
29125,offtarget_evidence,432,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for shRPL9.,2026-06-02T20:47:17+00:00
29126,offtarget_evidence,433,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for MALAT1.,2026-06-02T20:47:17+00:00
29127,offtarget_evidence,434,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for 11-15.,2026-06-02T20:47:17+00:00
29128,offtarget_evidence,435,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for nusinersen.,2026-06-02T20:47:17+00:00
29129,offtarget_evidence,436,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for ASO-001933.,2026-06-02T20:47:17+00:00
29130,offtarget_evidence,437,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for siRNA-3.,2026-06-02T20:47:17+00:00
29131,offtarget_evidence,438,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for GAAA-3.,2026-06-02T20:47:17+00:00
29132,offtarget_evidence,439,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for WT siRNA.,2026-06-02T20:47:17+00:00
29133,offtarget_evidence,440,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for BCL-2.,2026-06-02T20:47:17+00:00
29134,offtarget_evidence,441,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for T39 ASO.,2026-06-02T20:47:17+00:00
29135,offtarget_evidence,442,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for NR2E3-Associated.,2026-06-02T20:47:17+00:00
29136,offtarget_evidence,443,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for SSO-1.,2026-06-02T20:47:17+00:00
29137,offtarget_evidence,444,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for CTGTAGGCACCATCAAT-3.,2026-06-02T20:47:17+00:00
29138,offtarget_evidence,445,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for F5-3.,2026-06-02T20:47:17+00:00
29139,offtarget_evidence,446,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for VEGF siRNA.,2026-06-02T20:47:17+00:00
29140,offtarget_evidence,447,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for 42-49.,2026-06-02T20:47:17+00:00
29141,offtarget_evidence,448,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for PCSK9 ASO.,2026-06-02T20:47:17+00:00
29142,offtarget_evidence,449,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for HTT siRNA.,2026-06-02T20:47:17+00:00
29143,offtarget_evidence,450,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for HTT siRNA.,2026-06-02T20:47:17+00:00
29144,offtarget_evidence,451,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for IGF2BP2.,2026-06-02T20:47:17+00:00
29145,offtarget_evidence,452,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for AAV9; CMT1A.,2026-06-02T20:47:17+00:00
29146,offtarget_evidence,453,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for siPD-L1.,2026-06-02T20:47:17+00:00
29147,offtarget_evidence,454,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for FGFR2 siRNA.,2026-06-02T20:47:17+00:00
29148,offtarget_evidence,455,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for IRS2.,2026-06-02T20:47:17+00:00
29149,offtarget_evidence,456,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for modified siRNA.,2026-06-02T20:47:17+00:00
29150,offtarget_evidence,457,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for LNP-siRNA.,2026-06-02T20:47:17+00:00
29151,offtarget_evidence,458,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for PKM-ASO.,2026-06-02T20:47:17+00:00
29152,offtarget_evidence,459,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for AsOBP21f.,2026-06-02T20:47:17+00:00
29153,offtarget_evidence,460,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for shRNA-GNEM743T.,2026-06-02T20:47:17+00:00
29154,offtarget_evidence,461,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for PSMD1.,2026-06-02T20:47:17+00:00
29155,offtarget_evidence,462,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for si098-DV29P.,2026-06-02T20:47:17+00:00
29156,offtarget_evidence,463,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for YAP1; WWTR1.,2026-06-02T20:47:17+00:00
29157,offtarget_evidence,464,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for ACTB ASO.,2026-06-02T20:47:17+00:00
29158,offtarget_evidence,465,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for TNF ASO.,2026-06-02T20:47:17+00:00
29159,offtarget_evidence,466,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for EGFR siRNA.,2026-06-02T20:47:17+00:00
29160,offtarget_evidence,467,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for A4GALT-siRNA.,2026-06-02T20:47:17+00:00
29161,offtarget_evidence,468,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for 15 siRNA.,2026-06-02T20:47:17+00:00
29162,offtarget_evidence,469,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for CD47.,2026-06-02T20:47:17+00:00
29163,offtarget_evidence,470,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for EGFR-siRNA.,2026-06-02T20:47:17+00:00
29164,offtarget_evidence,471,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for SKOV3.,2026-06-02T20:47:17+00:00
29165,offtarget_evidence,472,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for BACE1.,2026-06-02T20:47:17+00:00
29166,offtarget_evidence,473,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for UU-3.,2026-06-02T20:47:17+00:00
29167,offtarget_evidence,474,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for NSUN4; CD8.,2026-06-02T20:47:17+00:00
29168,offtarget_evidence,475,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for sFRP2.,2026-06-02T20:47:17+00:00
29169,offtarget_evidence,476,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for siSmyd3.,2026-06-02T20:47:17+00:00
29170,offtarget_evidence,477,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for DUX4.,2026-06-02T20:47:17+00:00
29171,offtarget_evidence,478,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for CD39.,2026-06-02T20:47:17+00:00
29172,offtarget_evidence,479,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siRNA2.,2026-06-02T20:47:17+00:00
29173,offtarget_evidence,480,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siRNA8.,2026-06-02T20:47:17+00:00
29174,offtarget_evidence,481,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for CD81 ASO.,2026-06-02T20:47:17+00:00
29175,offtarget_evidence,482,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for CXCR4-Targeted.,2026-06-02T20:47:17+00:00
29176,offtarget_evidence,483,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for SMILR siRNA.,2026-06-02T20:47:17+00:00
29177,offtarget_evidence,484,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for KRAS siRNA.,2026-06-02T20:47:17+00:00
29178,offtarget_evidence,485,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for SSEA-2.,2026-06-02T20:47:17+00:00
29179,offtarget_evidence,486,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for KRAS siRNA.,2026-06-02T20:47:17+00:00
29180,offtarget_evidence,487,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for 0001 ASO.,2026-06-02T20:47:17+00:00
29181,offtarget_evidence,488,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for siSTT1.,2026-06-02T20:47:17+00:00
29182,offtarget_evidence,489,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for PA5-78644.,2026-06-02T20:47:17+00:00
29183,offtarget_evidence,490,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for STAT3.,2026-06-02T20:47:17+00:00
29184,offtarget_evidence,491,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for EZH2-driven.,2026-06-02T20:47:17+00:00
29185,offtarget_evidence,492,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for JAK1.,2026-06-02T20:47:17+00:00
29186,offtarget_evidence,493,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for PH-762.,2026-06-02T20:47:17+00:00
29187,offtarget_evidence,494,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for CCL7.,2026-06-02T20:47:17+00:00
29188,offtarget_evidence,495,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for HIF-1.,2026-06-02T20:47:17+00:00
29189,offtarget_evidence,496,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for APOE ASO.,2026-06-02T20:47:17+00:00
29190,offtarget_evidence,497,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for Il6.,2026-06-02T20:47:17+00:00
29191,offtarget_evidence,498,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for PS-ASO.,2026-06-02T20:47:17+00:00
29192,offtarget_evidence,499,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for nusinersen.,2026-06-02T20:47:17+00:00
29193,offtarget_evidence,500,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for BC-893.,2026-06-02T20:47:17+00:00
29194,offtarget_evidence,501,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for JAK1-selective.,2026-06-02T20:47:17+00:00
29195,offtarget_evidence,502,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for RBCEV siRNA.,2026-06-02T20:47:17+00:00
29196,offtarget_evidence,503,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for modified siRNA.,2026-06-02T20:47:17+00:00
29197,offtarget_evidence,504,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for Atp1a2; SOD1.,2026-06-02T20:47:17+00:00
29198,offtarget_evidence,505,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for C5-siRNA.,2026-06-02T20:47:17+00:00
29199,offtarget_evidence,506,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for siIGF1R-1.,2026-06-02T20:47:17+00:00
29200,offtarget_evidence,507,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for TR-siRNA.,2026-06-02T20:47:17+00:00
29201,offtarget_evidence,508,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for A01406-33.,2026-06-02T20:47:17+00:00
29202,offtarget_evidence,509,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for siT10.,2026-06-02T20:47:17+00:00
29203,offtarget_evidence,510,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for SLN360.,2026-06-02T20:47:17+00:00
29204,offtarget_evidence,511,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for LNA ASO.,2026-06-02T20:47:17+00:00
29205,offtarget_evidence,512,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for siCpWnt3.,2026-06-02T20:47:17+00:00
29206,offtarget_evidence,513,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for KCNQ1; QT1.,2026-06-02T20:47:17+00:00
29207,offtarget_evidence,514,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siHJ1D8.,2026-06-02T20:47:17+00:00
29208,offtarget_evidence,515,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for LINC01257.,2026-06-02T20:47:17+00:00
29209,offtarget_evidence,516,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for CAG-siRNA.,2026-06-02T20:47:17+00:00
29210,offtarget_evidence,517,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for EGFR siRNA.,2026-06-02T20:47:17+00:00
29211,offtarget_evidence,518,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for ORF1ab.,2026-06-02T20:47:17+00:00
29212,offtarget_evidence,519,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siUC7.,2026-06-02T20:47:17+00:00
29213,offtarget_evidence,520,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siCoV3.,2026-06-02T20:47:17+00:00
29214,offtarget_evidence,521,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for 207 siRNA.,2026-06-02T20:47:17+00:00
29215,offtarget_evidence,522,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for AS-siRNA.,2026-06-02T20:47:17+00:00
29216,offtarget_evidence,523,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for ADAR1.,2026-06-02T20:47:17+00:00
29217,offtarget_evidence,524,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for TPPP siRNA.,2026-06-02T20:47:17+00:00
29218,offtarget_evidence,525,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for eIF3m.,2026-06-02T20:47:17+00:00
29219,offtarget_evidence,526,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for HTT siRNA.,2026-06-02T20:47:17+00:00
29220,offtarget_evidence,527,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for 85 siRNA.,2026-06-02T20:47:17+00:00
29221,offtarget_evidence,528,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for SMARCB1.,2026-06-02T20:47:17+00:00
29222,offtarget_evidence,529,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for Serpinh1.,2026-06-02T20:47:17+00:00
29223,offtarget_evidence,530,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for CEP290; LCA10.,2026-06-02T20:47:17+00:00
29224,offtarget_evidence,531,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for GluN3A.,2026-06-02T20:47:17+00:00
29225,offtarget_evidence,532,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for 7C1 siRNA.,2026-06-02T20:47:17+00:00
29226,offtarget_evidence,533,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for Upf3b.,2026-06-02T20:47:17+00:00
29227,offtarget_evidence,534,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for 89E-06.,2026-06-02T20:47:17+00:00
29228,offtarget_evidence,535,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for LNA-siRNA.,2026-06-02T20:47:17+00:00
29229,offtarget_evidence,536,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for shRT5.,2026-06-02T20:47:17+00:00
29230,offtarget_evidence,537,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for VEGF siRNA.,2026-06-02T20:47:17+00:00
29231,offtarget_evidence,538,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for EGFR-siRNA.,2026-06-02T20:47:17+00:00
29232,offtarget_evidence,539,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for siCIP2A.,2026-06-02T20:47:17+00:00
29233,offtarget_evidence,540,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for MORC-1.,2026-06-02T20:47:17+00:00
29234,offtarget_evidence,541,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for HMGB1.,2026-06-02T20:47:17+00:00
29235,offtarget_evidence,542,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for 000 shRNA.,2026-06-02T20:47:17+00:00
29236,offtarget_evidence,543,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for TLR-3.,2026-06-02T20:47:17+00:00
29237,offtarget_evidence,544,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for 80 siRNA.,2026-06-02T20:47:17+00:00
29238,offtarget_evidence,545,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for OVCAR-8.,2026-06-02T20:47:17+00:00
29239,offtarget_evidence,546,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for PINK1 siRNA.,2026-06-02T20:47:17+00:00
29240,offtarget_evidence,547,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for siRND4.,2026-06-02T20:47:17+00:00
29241,offtarget_evidence,548,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for THIOMAB-siRNA.,2026-06-02T20:47:17+00:00
29242,offtarget_evidence,549,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for 20-70.,2026-06-02T20:47:17+00:00
29243,offtarget_evidence,550,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for IKK1.,2026-06-02T20:47:17+00:00
29244,offtarget_evidence,551,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for siEphA2.,2026-06-02T20:47:17+00:00
29245,offtarget_evidence,552,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for HIV-1.,2026-06-02T20:47:17+00:00
29246,offtarget_evidence,553,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for GAPDH siRNA.,2026-06-02T20:47:17+00:00
29247,offtarget_evidence,554,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for DARPP-32 siRNA.,2026-06-02T20:47:17+00:00
29248,offtarget_evidence,555,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for NRF2; KEAP1; CCL11.,2026-06-02T20:47:17+00:00
29249,offtarget_evidence,556,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as transcriptome-level off-target effect for 2016-27.,2026-06-02T20:47:17+00:00
29250,offtarget_evidence,557,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for CSNK2A1 siRNA.,2026-06-02T20:47:17+00:00
29251,offtarget_evidence,558,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for ss-siRNA.,2026-06-02T20:47:17+00:00
29252,offtarget_evidence,559,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for PEG-2000.,2026-06-02T20:47:17+00:00
29253,offtarget_evidence,560,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for SSB siRNA.,2026-06-02T20:47:17+00:00
29254,offtarget_evidence,561,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as seed-mediated off-target effect for QGP-1.,2026-06-02T20:47:17+00:00
29255,offtarget_evidence,562,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for STAT6.,2026-06-02T20:47:17+00:00
29256,offtarget_evidence,563,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as off-target evidence for LFA-1.,2026-06-02T20:47:17+00:00
29257,offtarget_evidence,564,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for LRRK2.,2026-06-02T20:47:17+00:00
29258,offtarget_evidence,565,curator_review_v1,promote_curator_review.py,machine_precurated_v1,accept,,Human verified PMC full-text anchor; accepted as hybridization/mismatch off-target effect for 21-5.,2026-06-02T20:47:17+00:00
29259,curation_candidate,38322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29260,curation_candidate,38327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29261,curation_candidate,38335,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29262,curation_candidate,38337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29263,curation_candidate,38339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29264,curation_candidate,38345,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29265,curation_candidate,38347,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29266,curation_candidate,38351,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29267,curation_candidate,38353,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29268,curation_candidate,38354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29269,curation_candidate,38355,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29270,curation_candidate,38358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29271,curation_candidate,38359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29272,curation_candidate,38361,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29273,curation_candidate,38362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29274,curation_candidate,38371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29275,curation_candidate,38372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29276,curation_candidate,38373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29277,curation_candidate,38378,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29278,curation_candidate,38379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29279,curation_candidate,38384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29280,curation_candidate,38388,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29281,curation_candidate,38391,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29282,curation_candidate,38392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29283,curation_candidate,38393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29284,curation_candidate,38394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29285,curation_candidate,38396,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29286,curation_candidate,38397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29287,curation_candidate,38399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29288,curation_candidate,38404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29289,curation_candidate,38406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29290,curation_candidate,38408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29291,curation_candidate,38410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29292,curation_candidate,38415,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29293,curation_candidate,38416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29294,curation_candidate,38420,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29295,curation_candidate,38424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29296,curation_candidate,38426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29297,curation_candidate,38427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29298,curation_candidate,38428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29299,curation_candidate,38429,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29300,curation_candidate,38431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29301,curation_candidate,38433,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
29302,curation_candidate,38434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29303,curation_candidate,38435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29304,curation_candidate,38438,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29305,curation_candidate,38441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29306,curation_candidate,38442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29307,curation_candidate,38443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29308,curation_candidate,38445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29309,curation_candidate,38450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29310,curation_candidate,38454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
29311,curation_candidate,38458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29312,curation_candidate,38459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29313,curation_candidate,38462,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29314,curation_candidate,38464,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29315,curation_candidate,38468,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29316,curation_candidate,38472,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29317,curation_candidate,38480,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29318,curation_candidate,38481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29319,curation_candidate,38486,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29320,curation_candidate,38491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: generic off-target statement without molecule-specific result,2026-06-02T20:47:17+00:00
29321,curation_candidate,38495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29322,curation_candidate,38496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29323,curation_candidate,38499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29324,curation_candidate,38501,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
29325,curation_candidate,38504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29326,curation_candidate,38505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29327,curation_candidate,38506,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29328,curation_candidate,38509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29329,curation_candidate,38511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29330,curation_candidate,38513,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29331,curation_candidate,38515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29332,curation_candidate,38516,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29333,curation_candidate,38518,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29334,curation_candidate,38519,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29335,curation_candidate,38520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29336,curation_candidate,38521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29337,curation_candidate,38522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29338,curation_candidate,38523,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29339,curation_candidate,38524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29340,curation_candidate,38525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29341,curation_candidate,38531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29342,curation_candidate,38534,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29343,curation_candidate,38540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29344,curation_candidate,38541,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29345,curation_candidate,38544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29346,curation_candidate,38545,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29347,curation_candidate,38546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29348,curation_candidate,38547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29349,curation_candidate,38548,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29350,curation_candidate,38549,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29351,curation_candidate,38556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29352,curation_candidate,38558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29353,curation_candidate,38559,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29354,curation_candidate,38560,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29355,curation_candidate,38564,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29356,curation_candidate,38565,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29357,curation_candidate,38570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29358,curation_candidate,38571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29359,curation_candidate,38572,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29360,curation_candidate,38575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29361,curation_candidate,38576,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29362,curation_candidate,38579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29363,curation_candidate,38581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29364,curation_candidate,38582,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29365,curation_candidate,38585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29366,curation_candidate,38588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29367,curation_candidate,38592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29368,curation_candidate,38594,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29369,curation_candidate,38596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29370,curation_candidate,38598,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29371,curation_candidate,38601,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29372,curation_candidate,38602,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29373,curation_candidate,38603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29374,curation_candidate,38604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29375,curation_candidate,38605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29376,curation_candidate,38606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29377,curation_candidate,38607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29378,curation_candidate,38609,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29379,curation_candidate,38617,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29380,curation_candidate,38619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29381,curation_candidate,38620,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29382,curation_candidate,38622,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29383,curation_candidate,38623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29384,curation_candidate,38626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29385,curation_candidate,38628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29386,curation_candidate,38630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29387,curation_candidate,38631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
29388,curation_candidate,38632,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29389,curation_candidate,38635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29390,curation_candidate,38637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29391,curation_candidate,38639,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29392,curation_candidate,38640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29393,curation_candidate,38642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29394,curation_candidate,38644,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29395,curation_candidate,38646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29396,curation_candidate,38647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29397,curation_candidate,38652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29398,curation_candidate,38660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29399,curation_candidate,38661,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29400,curation_candidate,38663,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29401,curation_candidate,38664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29402,curation_candidate,38665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29403,curation_candidate,38667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29404,curation_candidate,38669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29405,curation_candidate,38670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29406,curation_candidate,38672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29407,curation_candidate,38673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29408,curation_candidate,38676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29409,curation_candidate,38683,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29410,curation_candidate,38687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29411,curation_candidate,38690,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29412,curation_candidate,38699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29413,curation_candidate,38703,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29414,curation_candidate,38704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29415,curation_candidate,38708,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29416,curation_candidate,38715,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29417,curation_candidate,38716,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29418,curation_candidate,38720,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29419,curation_candidate,38721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
29420,curation_candidate,38722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29421,curation_candidate,38723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29422,curation_candidate,38724,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29423,curation_candidate,38726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29424,curation_candidate,38730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29425,curation_candidate,38735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29426,curation_candidate,38737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29427,curation_candidate,38738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29428,curation_candidate,38739,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29429,curation_candidate,38742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29430,curation_candidate,38743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29431,curation_candidate,38746,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29432,curation_candidate,38751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29433,curation_candidate,38754,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29434,curation_candidate,38757,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29435,curation_candidate,38760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29436,curation_candidate,38761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29437,curation_candidate,38763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29438,curation_candidate,38764,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29439,curation_candidate,38773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29440,curation_candidate,38776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29441,curation_candidate,38777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29442,curation_candidate,38779,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29443,curation_candidate,38782,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29444,curation_candidate,38784,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29445,curation_candidate,38789,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29446,curation_candidate,38796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29447,curation_candidate,38798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29448,curation_candidate,38799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29449,curation_candidate,38802,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29450,curation_candidate,38805,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29451,curation_candidate,38807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29452,curation_candidate,38809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29453,curation_candidate,38810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29454,curation_candidate,38824,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29455,curation_candidate,38825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29456,curation_candidate,38827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29457,curation_candidate,38830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29458,curation_candidate,38834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29459,curation_candidate,38838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29460,curation_candidate,38840,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29461,curation_candidate,38841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29462,curation_candidate,38842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29463,curation_candidate,38843,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29464,curation_candidate,38846,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29465,curation_candidate,38849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29466,curation_candidate,38850,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29467,curation_candidate,38855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29468,curation_candidate,38862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29469,curation_candidate,38864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29470,curation_candidate,38867,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29471,curation_candidate,38872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29472,curation_candidate,38873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29473,curation_candidate,38877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29474,curation_candidate,38881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29475,curation_candidate,38883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29476,curation_candidate,38884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29477,curation_candidate,38890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29478,curation_candidate,38891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29479,curation_candidate,38898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29480,curation_candidate,38900,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29481,curation_candidate,38901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29482,curation_candidate,38902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29483,curation_candidate,38909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29484,curation_candidate,38916,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29485,curation_candidate,38917,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29486,curation_candidate,38947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29487,curation_candidate,38950,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29488,curation_candidate,38951,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29489,curation_candidate,38952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29490,curation_candidate,38960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29491,curation_candidate,38962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29492,curation_candidate,38963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29493,curation_candidate,38965,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29494,curation_candidate,38966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29495,curation_candidate,38968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29496,curation_candidate,38974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29497,curation_candidate,38977,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
29498,curation_candidate,38980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29499,curation_candidate,38985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29500,curation_candidate,38987,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29501,curation_candidate,38991,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29502,curation_candidate,38992,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29503,curation_candidate,38996,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29504,curation_candidate,38998,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29505,curation_candidate,39002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29506,curation_candidate,39006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29507,curation_candidate,39016,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29508,curation_candidate,39019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29509,curation_candidate,39020,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29510,curation_candidate,39021,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29511,curation_candidate,39023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29512,curation_candidate,39024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29513,curation_candidate,39025,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29514,curation_candidate,39028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29515,curation_candidate,39029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29516,curation_candidate,39044,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29517,curation_candidate,39046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29518,curation_candidate,39047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29519,curation_candidate,39049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29520,curation_candidate,39057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29521,curation_candidate,39059,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29522,curation_candidate,39060,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29523,curation_candidate,39062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29524,curation_candidate,39063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29525,curation_candidate,39066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29526,curation_candidate,39067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29527,curation_candidate,39070,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29528,curation_candidate,39071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29529,curation_candidate,39073,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29530,curation_candidate,39074,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29531,curation_candidate,39078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29532,curation_candidate,39079,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29533,curation_candidate,39092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29534,curation_candidate,39095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29535,curation_candidate,39097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29536,curation_candidate,39100,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29537,curation_candidate,39101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29538,curation_candidate,39102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29539,curation_candidate,39110,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29540,curation_candidate,39114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29541,curation_candidate,39116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29542,curation_candidate,39118,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29543,curation_candidate,39126,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29544,curation_candidate,39127,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29545,curation_candidate,39130,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29546,curation_candidate,39133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29547,curation_candidate,39135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29548,curation_candidate,39144,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29549,curation_candidate,39145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29550,curation_candidate,39146,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
29551,curation_candidate,39149,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29552,curation_candidate,39153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29553,curation_candidate,39156,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29554,curation_candidate,39158,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29555,curation_candidate,39160,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29556,curation_candidate,39167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29557,curation_candidate,39169,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29558,curation_candidate,39172,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29559,curation_candidate,39174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29560,curation_candidate,39175,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29561,curation_candidate,39176,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29562,curation_candidate,39180,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29563,curation_candidate,39184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29564,curation_candidate,39187,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29565,curation_candidate,39188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29566,curation_candidate,39189,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29567,curation_candidate,39192,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29568,curation_candidate,39197,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29569,curation_candidate,39199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: off-target statement is not supported by primary result text,2026-06-02T20:47:17+00:00
29570,curation_candidate,39203,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29571,curation_candidate,39207,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29572,curation_candidate,39208,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29573,curation_candidate,39209,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29574,curation_candidate,39210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29575,curation_candidate,39214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29576,curation_candidate,39215,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29577,curation_candidate,39221,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29578,curation_candidate,39225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29579,curation_candidate,39235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29580,curation_candidate,39237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29581,curation_candidate,39240,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29582,curation_candidate,39242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29583,curation_candidate,39243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29584,curation_candidate,39249,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29585,curation_candidate,39258,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29586,curation_candidate,39268,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29587,curation_candidate,39271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29588,curation_candidate,39274,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29589,curation_candidate,39279,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29590,curation_candidate,39281,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29591,curation_candidate,39283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29592,curation_candidate,39284,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29593,curation_candidate,39287,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29594,curation_candidate,39288,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29595,curation_candidate,39289,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29596,curation_candidate,39290,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29597,curation_candidate,39292,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29598,curation_candidate,39297,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29599,curation_candidate,39300,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29600,curation_candidate,39301,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29601,curation_candidate,39302,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29602,curation_candidate,39305,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29603,curation_candidate,39306,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29604,curation_candidate,39309,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29605,curation_candidate,39310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29606,curation_candidate,39319,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29607,curation_candidate,39326,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29608,curation_candidate,39327,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29609,curation_candidate,39331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29610,curation_candidate,39333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29611,curation_candidate,39334,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29612,curation_candidate,39337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29613,curation_candidate,39339,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29614,curation_candidate,39342,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29615,curation_candidate,39350,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29616,curation_candidate,39356,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29617,curation_candidate,39358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29618,curation_candidate,39359,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29619,curation_candidate,39362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29620,curation_candidate,39364,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29621,curation_candidate,39365,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29622,curation_candidate,39366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29623,curation_candidate,39369,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29624,curation_candidate,39370,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29625,curation_candidate,39371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29626,curation_candidate,39376,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29627,curation_candidate,39379,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
29628,curation_candidate,39380,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29629,curation_candidate,39381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29630,curation_candidate,39382,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29631,curation_candidate,39383,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29632,curation_candidate,39390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29633,curation_candidate,39397,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29634,curation_candidate,39399,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29635,curation_candidate,39401,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29636,curation_candidate,39402,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29637,curation_candidate,39404,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29638,curation_candidate,39410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29639,curation_candidate,39422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29640,curation_candidate,39425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29641,curation_candidate,39426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29642,curation_candidate,39427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29643,curation_candidate,39432,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29644,curation_candidate,39435,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29645,curation_candidate,39440,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29646,curation_candidate,39443,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29647,curation_candidate,39445,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29648,curation_candidate,39446,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29649,curation_candidate,39449,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29650,curation_candidate,39451,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29651,curation_candidate,39457,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29652,curation_candidate,39458,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29653,curation_candidate,39459,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29654,curation_candidate,39465,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29655,curation_candidate,39471,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29656,curation_candidate,39474,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29657,curation_candidate,39475,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29658,curation_candidate,39481,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29659,curation_candidate,39485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29660,curation_candidate,39487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29661,curation_candidate,39489,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29662,curation_candidate,39490,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29663,curation_candidate,39493,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29664,curation_candidate,39497,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29665,curation_candidate,39498,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29666,curation_candidate,39499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29667,curation_candidate,39505,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29668,curation_candidate,39509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29669,curation_candidate,39511,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29670,curation_candidate,39514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29671,curation_candidate,39517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29672,curation_candidate,39522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29673,curation_candidate,39524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29674,curation_candidate,39526,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29675,curation_candidate,39527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29676,curation_candidate,39529,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29677,curation_candidate,39531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29678,curation_candidate,39563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29679,curation_candidate,39567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29680,curation_candidate,39569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29681,curation_candidate,39570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29682,curation_candidate,39579,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29683,curation_candidate,39580,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29684,curation_candidate,39581,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29685,curation_candidate,39583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29686,curation_candidate,39593,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29687,curation_candidate,39603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29688,curation_candidate,39606,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29689,curation_candidate,39608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29690,curation_candidate,39611,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29691,curation_candidate,39612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29692,curation_candidate,39613,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29693,curation_candidate,39616,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29694,curation_candidate,39618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29695,curation_candidate,39623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29696,curation_candidate,39624,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29697,curation_candidate,39631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29698,curation_candidate,39634,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29699,curation_candidate,39635,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29700,curation_candidate,39638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29701,curation_candidate,39645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29702,curation_candidate,39646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29703,curation_candidate,39647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29704,curation_candidate,39650,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29705,curation_candidate,39651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29706,curation_candidate,39652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29707,curation_candidate,39655,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29708,curation_candidate,39656,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29709,curation_candidate,39659,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29710,curation_candidate,39660,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29711,curation_candidate,39665,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29712,curation_candidate,39666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29713,curation_candidate,39667,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29714,curation_candidate,39669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29715,curation_candidate,39671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29716,curation_candidate,39675,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29717,curation_candidate,39676,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29718,curation_candidate,39680,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29719,curation_candidate,39682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29720,curation_candidate,39686,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29721,curation_candidate,39687,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29722,curation_candidate,39689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29723,curation_candidate,39692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29724,curation_candidate,39696,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29725,curation_candidate,39699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29726,curation_candidate,39702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29727,curation_candidate,39704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29728,curation_candidate,39707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29729,curation_candidate,39710,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29730,curation_candidate,39711,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29731,curation_candidate,39712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29732,curation_candidate,39714,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29733,curation_candidate,39718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29734,curation_candidate,39723,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29735,curation_candidate,39725,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29736,curation_candidate,39726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29737,curation_candidate,39730,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29738,curation_candidate,39731,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29739,curation_candidate,39732,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29740,curation_candidate,39735,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29741,curation_candidate,39749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29742,curation_candidate,39750,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29743,curation_candidate,39758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29744,curation_candidate,39761,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29745,curation_candidate,39762,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29746,curation_candidate,39767,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29747,curation_candidate,39770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29748,curation_candidate,39771,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29749,curation_candidate,39774,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29750,curation_candidate,39775,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29751,curation_candidate,39776,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29752,curation_candidate,39777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29753,curation_candidate,39781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29754,curation_candidate,39783,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29755,curation_candidate,39787,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29756,curation_candidate,39794,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29757,curation_candidate,39795,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29758,curation_candidate,39796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29759,curation_candidate,39800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29760,curation_candidate,39803,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29761,curation_candidate,39804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29762,curation_candidate,39808,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29763,curation_candidate,39809,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29764,curation_candidate,39810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29765,curation_candidate,39813,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29766,curation_candidate,39818,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29767,curation_candidate,39822,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29768,curation_candidate,39825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29769,curation_candidate,39826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29770,curation_candidate,39827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29771,curation_candidate,39832,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29772,curation_candidate,39834,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29773,curation_candidate,39844,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29774,curation_candidate,39845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29775,curation_candidate,39848,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29776,curation_candidate,39849,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29777,curation_candidate,39853,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29778,curation_candidate,39854,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29779,curation_candidate,39855,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29780,curation_candidate,39861,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29781,curation_candidate,39864,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29782,curation_candidate,39866,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29783,curation_candidate,39868,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29784,curation_candidate,39869,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29785,curation_candidate,39871,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29786,curation_candidate,39872,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29787,curation_candidate,39873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29788,curation_candidate,39874,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29789,curation_candidate,39877,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29790,curation_candidate,39879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29791,curation_candidate,39884,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29792,curation_candidate,39890,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29793,curation_candidate,39891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29794,curation_candidate,39893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29795,curation_candidate,39894,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29796,curation_candidate,39895,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29797,curation_candidate,39896,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29798,curation_candidate,39898,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29799,curation_candidate,39899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29800,curation_candidate,39901,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29801,curation_candidate,39903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29802,curation_candidate,39905,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29803,curation_candidate,39906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29804,curation_candidate,39909,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29805,curation_candidate,39910,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29806,curation_candidate,39911,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29807,curation_candidate,39919,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29808,curation_candidate,39920,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29809,curation_candidate,39921,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29810,curation_candidate,39923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29811,curation_candidate,39924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29812,curation_candidate,39927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29813,curation_candidate,39928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29814,curation_candidate,39931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29815,curation_candidate,39932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29816,curation_candidate,39935,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29817,curation_candidate,39936,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29818,curation_candidate,39938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29819,curation_candidate,39946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29820,curation_candidate,39947,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29821,curation_candidate,39948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29822,curation_candidate,39952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29823,curation_candidate,39954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29824,curation_candidate,39956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29825,curation_candidate,39957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29826,curation_candidate,39960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29827,curation_candidate,39964,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29828,curation_candidate,39967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29829,curation_candidate,39969,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29830,curation_candidate,39970,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29831,curation_candidate,39971,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29832,curation_candidate,39973,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29833,curation_candidate,39978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29834,curation_candidate,39985,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29835,curation_candidate,39988,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29836,curation_candidate,39993,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29837,curation_candidate,39997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29838,curation_candidate,39999,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29839,curation_candidate,40003,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29840,curation_candidate,40006,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29841,curation_candidate,40009,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29842,curation_candidate,40011,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29843,curation_candidate,40014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29844,curation_candidate,40018,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29845,curation_candidate,40022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29846,curation_candidate,40024,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29847,curation_candidate,40026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29848,curation_candidate,40027,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29849,curation_candidate,40028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29850,curation_candidate,40029,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29851,curation_candidate,40030,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29852,curation_candidate,40031,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29853,curation_candidate,40033,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29854,curation_candidate,40036,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29855,curation_candidate,40040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29856,curation_candidate,40042,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29857,curation_candidate,40045,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29858,curation_candidate,40047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29859,curation_candidate,40049,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29860,curation_candidate,40050,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29861,curation_candidate,40056,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29862,curation_candidate,40057,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29863,curation_candidate,40058,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29864,curation_candidate,40063,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29865,curation_candidate,40064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29866,curation_candidate,40065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29867,curation_candidate,40067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29868,curation_candidate,40068,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29869,curation_candidate,40069,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29870,curation_candidate,40071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29871,curation_candidate,40075,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29872,curation_candidate,40077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29873,curation_candidate,40086,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29874,curation_candidate,40087,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29875,curation_candidate,40092,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29876,curation_candidate,40095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29877,curation_candidate,40096,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29878,curation_candidate,40097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29879,curation_candidate,40101,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29880,curation_candidate,40107,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29881,curation_candidate,40111,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29882,curation_candidate,40116,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29883,curation_candidate,40122,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29884,curation_candidate,40133,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29885,curation_candidate,40135,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29886,curation_candidate,40141,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29887,curation_candidate,40142,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29888,curation_candidate,40145,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29889,curation_candidate,40147,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29890,curation_candidate,40153,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29891,curation_candidate,40159,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29892,curation_candidate,40161,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29893,curation_candidate,40166,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29894,curation_candidate,40167,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29895,curation_candidate,40170,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29896,curation_candidate,40173,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29897,curation_candidate,40174,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29898,curation_candidate,40178,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29899,curation_candidate,40184,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T20:47:17+00:00
29900,curation_candidate,40185,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29901,curation_candidate,40188,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29902,curation_candidate,40190,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29903,curation_candidate,40191,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: review/background article, not primary off-target evidence",2026-06-02T20:47:17+00:00
29904,curation_candidate,40194,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29905,curation_candidate,40195,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29906,curation_candidate,40198,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29907,curation_candidate,40199,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29908,curation_candidate,40201,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29909,curation_candidate,40202,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29910,curation_candidate,40210,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29911,curation_candidate,40213,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29912,curation_candidate,40214,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29913,curation_candidate,40216,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29914,curation_candidate,40225,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29915,curation_candidate,40226,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29916,curation_candidate,40227,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29917,curation_candidate,40228,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29918,curation_candidate,40230,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29919,curation_candidate,40232,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29920,curation_candidate,40235,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29921,curation_candidate,40237,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29922,curation_candidate,40238,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29923,curation_candidate,40242,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29924,curation_candidate,40243,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29925,curation_candidate,40247,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29926,curation_candidate,40256,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29927,curation_candidate,40259,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29928,curation_candidate,40262,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29929,curation_candidate,40263,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29930,curation_candidate,40271,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29931,curation_candidate,40273,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29932,curation_candidate,40282,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29933,curation_candidate,40283,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29934,curation_candidate,40285,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29935,curation_candidate,40293,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29936,curation_candidate,40294,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29937,curation_candidate,40296,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29938,curation_candidate,40299,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29939,curation_candidate,40304,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29940,curation_candidate,40310,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29941,curation_candidate,40312,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29942,curation_candidate,40314,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29943,curation_candidate,40316,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29944,curation_candidate,40317,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29945,curation_candidate,40318,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29946,curation_candidate,40320,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29947,curation_candidate,40321,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29948,curation_candidate,40322,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29949,curation_candidate,40329,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29950,curation_candidate,40331,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29951,curation_candidate,40333,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29952,curation_candidate,40336,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29953,curation_candidate,40337,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29954,curation_candidate,40338,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29955,curation_candidate,40346,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29956,curation_candidate,40348,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29957,curation_candidate,40354,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29958,curation_candidate,40358,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29959,curation_candidate,40362,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29960,curation_candidate,40363,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29961,curation_candidate,40366,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29962,curation_candidate,40368,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29963,curation_candidate,40371,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29964,curation_candidate,40372,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29965,curation_candidate,40373,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29966,curation_candidate,40374,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29967,curation_candidate,40381,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29968,curation_candidate,40384,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29969,curation_candidate,40386,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29970,curation_candidate,40390,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29971,curation_candidate,40392,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29972,curation_candidate,40393,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29973,curation_candidate,40394,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29974,curation_candidate,40398,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29975,curation_candidate,40405,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29976,curation_candidate,40406,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29977,curation_candidate,40407,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29978,curation_candidate,40408,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29979,curation_candidate,40410,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29980,curation_candidate,40416,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29981,curation_candidate,40418,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29982,curation_candidate,40419,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29983,curation_candidate,40422,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
29984,curation_candidate,40424,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29985,curation_candidate,40425,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29986,curation_candidate,40426,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29987,curation_candidate,40427,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29988,curation_candidate,40428,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
29989,curation_candidate,40431,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29990,curation_candidate,40434,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29991,curation_candidate,40441,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29992,curation_candidate,40442,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29993,curation_candidate,40447,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29994,curation_candidate,40448,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
29995,curation_candidate,40450,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29996,curation_candidate,40452,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29997,curation_candidate,40453,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
29998,curation_candidate,40454,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
29999,curation_candidate,40456,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30000,curation_candidate,40460,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30001,curation_candidate,40473,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30002,curation_candidate,40476,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30003,curation_candidate,40478,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30004,curation_candidate,40483,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30005,curation_candidate,40484,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30006,curation_candidate,40485,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30007,curation_candidate,40487,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30008,curation_candidate,40491,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30009,curation_candidate,40492,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30010,curation_candidate,40495,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30011,curation_candidate,40496,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30012,curation_candidate,40499,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30013,curation_candidate,40504,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30014,curation_candidate,40509,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30015,curation_candidate,40510,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30016,curation_candidate,40514,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30017,curation_candidate,40515,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30018,curation_candidate,40517,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30019,curation_candidate,40520,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30020,curation_candidate,40521,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30021,curation_candidate,40522,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30022,curation_candidate,40524,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30023,curation_candidate,40525,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30024,curation_candidate,40527,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30025,curation_candidate,40530,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30026,curation_candidate,40531,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30027,curation_candidate,40533,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30028,curation_candidate,40536,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30029,curation_candidate,40537,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30030,curation_candidate,40539,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30031,curation_candidate,40540,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30032,curation_candidate,40542,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30033,curation_candidate,40543,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30034,curation_candidate,40544,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30035,curation_candidate,40546,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30036,curation_candidate,40547,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30037,curation_candidate,40551,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30038,curation_candidate,40554,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30039,curation_candidate,40555,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30040,curation_candidate,40556,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30041,curation_candidate,40557,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30042,curation_candidate,40558,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30043,curation_candidate,40561,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30044,curation_candidate,40563,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30045,curation_candidate,40567,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30046,curation_candidate,40568,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30047,curation_candidate,40569,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30048,curation_candidate,40570,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30049,curation_candidate,40571,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30050,curation_candidate,40575,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30051,curation_candidate,40583,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30052,curation_candidate,40585,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30053,curation_candidate,40586,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30054,curation_candidate,40587,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30055,curation_candidate,40588,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30056,curation_candidate,40592,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30057,curation_candidate,40595,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30058,curation_candidate,40596,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30059,curation_candidate,40597,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30060,curation_candidate,40600,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30061,curation_candidate,40603,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30062,curation_candidate,40604,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30063,curation_candidate,40605,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30064,curation_candidate,40607,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30065,curation_candidate,40608,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30066,curation_candidate,40610,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30067,curation_candidate,40612,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30068,curation_candidate,40614,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30069,curation_candidate,40615,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30070,curation_candidate,40618,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30071,curation_candidate,40619,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30072,curation_candidate,40621,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30073,curation_candidate,40623,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30074,curation_candidate,40625,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30075,curation_candidate,40626,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30076,curation_candidate,40627,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30077,curation_candidate,40628,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30078,curation_candidate,40629,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30079,curation_candidate,40630,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30080,curation_candidate,40631,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30081,curation_candidate,40633,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30082,curation_candidate,40637,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30083,curation_candidate,40638,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30084,curation_candidate,40640,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30085,curation_candidate,40642,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30086,curation_candidate,40645,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30087,curation_candidate,40646,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30088,curation_candidate,40647,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30089,curation_candidate,40651,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30090,curation_candidate,40652,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30091,curation_candidate,40653,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30092,curation_candidate,40657,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30093,curation_candidate,40658,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30094,curation_candidate,40662,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30095,curation_candidate,40664,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30096,curation_candidate,40666,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30097,curation_candidate,40668,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30098,curation_candidate,40669,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30099,curation_candidate,40670,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30100,curation_candidate,40671,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30101,curation_candidate,40672,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30102,curation_candidate,40673,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
30103,curation_candidate,40674,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30104,curation_candidate,40679,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30105,curation_candidate,40682,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30106,curation_candidate,40688,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30107,curation_candidate,40689,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30108,curation_candidate,40692,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30109,curation_candidate,40693,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30110,curation_candidate,40697,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30111,curation_candidate,40699,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30112,curation_candidate,40701,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30113,curation_candidate,40702,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30114,curation_candidate,40704,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30115,curation_candidate,40705,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30116,curation_candidate,40706,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30117,curation_candidate,40707,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30118,curation_candidate,40712,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30119,curation_candidate,40717,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30120,curation_candidate,40718,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30121,curation_candidate,40721,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30122,curation_candidate,40722,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30123,curation_candidate,40726,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30124,curation_candidate,40729,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30125,curation_candidate,40734,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30126,curation_candidate,40737,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30127,curation_candidate,40738,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30128,curation_candidate,40742,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30129,curation_candidate,40743,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30130,curation_candidate,40747,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30131,curation_candidate,40748,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30132,curation_candidate,40749,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30133,curation_candidate,40751,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30134,curation_candidate,40753,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30135,curation_candidate,40756,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30136,curation_candidate,40758,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30137,curation_candidate,40760,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30138,curation_candidate,40763,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30139,curation_candidate,40768,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30140,curation_candidate,40770,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30141,curation_candidate,40772,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30142,curation_candidate,40773,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30143,curation_candidate,40777,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30144,curation_candidate,40780,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30145,curation_candidate,40781,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30146,curation_candidate,40785,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30147,curation_candidate,40788,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30148,curation_candidate,40791,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30149,curation_candidate,40792,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30150,curation_candidate,40796,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30151,curation_candidate,40798,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30152,curation_candidate,40799,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30153,curation_candidate,40800,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30154,curation_candidate,40801,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30155,curation_candidate,40804,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30156,curation_candidate,40807,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30157,curation_candidate,40810,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30158,curation_candidate,40812,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30159,curation_candidate,40817,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30160,curation_candidate,40819,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30161,curation_candidate,40821,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30162,curation_candidate,40825,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30163,curation_candidate,40826,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30164,curation_candidate,40827,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30165,curation_candidate,40828,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30166,curation_candidate,40829,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30167,curation_candidate,40830,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30168,curation_candidate,40835,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30169,curation_candidate,40837,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30170,curation_candidate,40838,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30171,curation_candidate,40839,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30172,curation_candidate,40841,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30173,curation_candidate,40842,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30174,curation_candidate,40845,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30175,curation_candidate,40852,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30176,curation_candidate,40857,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30177,curation_candidate,40859,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30178,curation_candidate,40862,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30179,curation_candidate,40863,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30180,curation_candidate,40865,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30181,curation_candidate,40873,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30182,curation_candidate,40878,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30183,curation_candidate,40879,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
30184,curation_candidate,40881,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30185,curation_candidate,40883,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30186,curation_candidate,40886,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30187,curation_candidate,40888,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30188,curation_candidate,40891,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30189,curation_candidate,40893,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30190,curation_candidate,40899,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30191,curation_candidate,40902,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30192,curation_candidate,40903,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30193,curation_candidate,40904,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30194,curation_candidate,40906,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30195,curation_candidate,40907,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30196,curation_candidate,40908,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30197,curation_candidate,40912,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30198,curation_candidate,40913,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30199,curation_candidate,40915,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30200,curation_candidate,40923,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30201,curation_candidate,40924,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30202,curation_candidate,40926,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30203,curation_candidate,40927,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30204,curation_candidate,40928,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30205,curation_candidate,40929,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30206,curation_candidate,40930,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30207,curation_candidate,40931,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30208,curation_candidate,40932,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30209,curation_candidate,40934,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30210,curation_candidate,40937,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30211,curation_candidate,40938,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30212,curation_candidate,40940,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30213,curation_candidate,40945,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30214,curation_candidate,40946,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30215,curation_candidate,40948,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30216,curation_candidate,40949,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30217,curation_candidate,40952,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30218,curation_candidate,40954,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30219,curation_candidate,40956,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30220,curation_candidate,40957,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30221,curation_candidate,40958,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30222,curation_candidate,40959,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30223,curation_candidate,40960,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30224,curation_candidate,40961,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
30225,curation_candidate,40962,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30226,curation_candidate,40963,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30227,curation_candidate,40966,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30228,curation_candidate,40967,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30229,curation_candidate,40968,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30230,curation_candidate,40974,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30231,curation_candidate,40975,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30232,curation_candidate,40976,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30233,curation_candidate,40978,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30234,curation_candidate,40979,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30235,curation_candidate,40980,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30236,curation_candidate,40984,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30237,curation_candidate,40986,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30238,curation_candidate,40994,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30239,curation_candidate,40995,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30240,curation_candidate,40997,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30241,curation_candidate,41000,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30242,curation_candidate,41001,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30243,curation_candidate,41002,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30244,curation_candidate,41014,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30245,curation_candidate,41017,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30246,curation_candidate,41019,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30247,curation_candidate,41022,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30248,curation_candidate,41023,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30249,curation_candidate,41026,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30250,curation_candidate,41028,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30251,curation_candidate,41037,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30252,curation_candidate,41038,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30253,curation_candidate,41040,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30254,curation_candidate,41046,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30255,curation_candidate,41047,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30256,curation_candidate,41052,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks explicit ASO/siRNA/oligonucleotide context,2026-06-02T20:47:17+00:00
30257,curation_candidate,41061,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30258,curation_candidate,41062,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30259,curation_candidate,41064,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30260,curation_candidate,41065,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30261,curation_candidate,41066,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30262,curation_candidate,41067,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30263,curation_candidate,41071,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30264,curation_candidate,41077,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30265,curation_candidate,41078,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,"reject reason: method/tool article, not molecule-specific release evidence",2026-06-02T20:47:17+00:00
30266,curation_candidate,41080,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30267,curation_candidate,41083,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30268,curation_candidate,41084,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30269,curation_candidate,41089,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30270,curation_candidate,41093,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30271,curation_candidate,41094,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: full-text anchor is background/discussion rather than primary evidence,2026-06-02T20:47:17+00:00
30272,curation_candidate,41095,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30273,curation_candidate,41097,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: out-of-scope organism or non-therapeutic oligonucleotide context,2026-06-02T20:47:17+00:00
30274,curation_candidate,41098,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30275,curation_candidate,41102,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30276,curation_candidate,41103,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30277,curation_candidate,41105,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30278,curation_candidate,41109,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: no explicit molecule name in verified source context,2026-06-02T20:47:17+00:00
30279,curation_candidate,41112,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30280,curation_candidate,41113,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30281,curation_candidate,41114,curator_review_v1,promote_curator_review.py,curator_rejected,reject,,reject reason: anchor text lacks specific off-target evidence,2026-06-02T20:47:17+00:00
30282,offtarget_evidence,1,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The greatest impact of SNA modification was observed when included at position g7 in si-50, with a relative off-target IC50 increase of ~260-fold over the parent si-47.",2026-06-07T02:20:35+00:00
30283,offtarget_evidence,2,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The effects on off-target genes were validated by microarray and RT-qPCR analyses.,2026-06-07T02:20:35+00:00
30284,offtarget_evidence,3,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,devoid of off-target AMPAR interaction and CNS toxicity while preserving the potency against the on-target miR-17.,2026-06-07T02:20:35+00:00
30285,offtarget_evidence,4,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In this study, we used three different splice-switching AONs targeting three different human transcripts to study their transcriptome-wide, hybridization-dependent off-target effects with short read RNAseq.",2026-06-07T02:20:35+00:00
30286,offtarget_evidence,5,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 38042877; pmc_full_text evidence was direct but less than full primary-detail confidence for hybridization/mismatch off-target effect.,2026-06-07T02:20:35+00:00
30287,offtarget_evidence,6,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"by performing RNA sequencing (RNA-seq) for cells after ASO treatment, we assessed both on- and off-target effects of the ASOs on a transcriptome-wide level.",2026-06-07T02:20:35+00:00
30288,offtarget_evidence,7,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We found that the ESC+ version of ALN-HBV, named ALN-HBV02, with a single GNA substitution at position 6 of the guide strand, and without any further changes in sequence or chemistry, minimizes off-target dysregulation without compromising on-target activity.",2026-06-07T02:20:35+00:00
30289,offtarget_evidence,8,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Consistent with these data, global transcriptome profiling by RNAseq shows RISC loading-dependent downregulation of RNAs enriched for a seed match to the antisense but not the sense strand of GalNAc-siRNAs.",2026-06-07T02:20:35+00:00
30290,offtarget_evidence,9,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 29860520; Out of scope: transcriptome-wide comparison of RNAi/LNA/CRISPRi loss-of-function tools, including lncRNA biology and CRISPRi, not therapeutic oligonucleotide safety evidence.",2026-06-07T02:20:35+00:00
30291,offtarget_evidence,10,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,We demonstrate in vitro mRNA and protein knockdown of off-targets with a wide range of mismatch (MM) and gap patterns.,2026-06-07T02:20:35+00:00
30292,offtarget_evidence,11,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41755844; Reject under v2: source mainly reports design, strand loading, Tm, and near-complementary duplex discrimination; it explicitly leaves RISC-mediated off-target and transcriptome-wide assays for future work, so no primary observed unintended off-target effect.",2026-06-07T02:20:35+00:00
30293,offtarget_evidence,12,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 41020503; weak/generic or abstract-limited support for seed-mediated off-target effect.,2026-06-07T02:20:35+00:00
30294,offtarget_evidence,13,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 36229039; weak/generic or abstract-limited support for hybridization/mismatch off-target effect.,2026-06-07T02:20:35+00:00
30295,offtarget_evidence,14,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 29499955; previous accept was too weak/generic for hybridization/mismatch off-target effect in ASO candidate from PMID 29499955. Basis checked: Generic high-affinity LNA-ASO panel links hepatotoxicity to RNase H1-dependent off-target RNA downregulation; molecule is not a single named therapeutic candidate, so grade C.",2026-06-07T02:20:35+00:00
30296,offtarget_evidence,15,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"When the MOE on the guide strand was combined with OMe at position 14 on the passenger strand, the off-target silencing was almost completely eliminated (Figure 8B).",2026-06-07T02:20:35+00:00
30297,offtarget_evidence,16,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C as borderline: PMID 41897327; curator counted sequence-specificity/off-target evidence for siRNA candidate from PMID 41897327 despite v2 exclusion. Low-confidence override; v2 note was: Reject under v2: passage supports allele-specific on-target silencing of mutant TDP-43 and cellular phenotype rescue, not observed unintended off-target evidence.",2026-06-07T02:20:35+00:00
30298,offtarget_evidence,17,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41743270; Reject under v2: review/future-perspective passage discusses allele-selective VWF silencing and says off-target effects still need evaluation; no primary measured off-target result.,2026-06-07T02:20:35+00:00
30299,offtarget_evidence,18,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 25539920; previous accept was too weak/generic for off-target evidence in ASO candidate from PMID 25539920. Basis checked: Synthetic anti-miR oligonucleotide study directly observes sequence-dependent off-target inhibition of TLR7/8 sensing, but context is mainly mechanistic/lab-use so grade C.",2026-06-07T02:20:35+00:00
30300,offtarget_evidence,19,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Importantly, differential gene expression (DGE) analysis showed a significant reduction in off-target effects across in vitro and in vivo, leading to an improved therapeutic profile.",2026-06-07T02:20:35+00:00
30301,offtarget_evidence,20,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,we conducted strand-specific RNA sequencing (RNA-seq) to quantify off-target effects of siRNAs bearing,2026-06-07T02:20:35+00:00
30302,offtarget_evidence,21,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Dual luciferase and RT-qPCR assays in HeLa cells showed that, in a model system of unmodified siRNAs, the amide linkage at position 3 (between nucleosides 3 and 4) suppressed cleavage of off-target YY1 and FADD mRNAs similarly to the industry gold standard modification, glycol nucleic acid (GNA).",2026-06-07T02:20:35+00:00
30303,offtarget_evidence,22,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,revealed a significant suppression of off-target activity while maintaining on-target RNAi activity.,2026-06-07T02:20:35+00:00
30304,offtarget_evidence,23,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,placement of the antisense strand at position 7 mitigated seed-based off-target effects in cell-based assays.,2026-06-07T02:20:35+00:00
30305,offtarget_evidence,24,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,microarray analysis was performed. Unmodified and modified siVIM-270s were transfected into HeLa cells,2026-06-07T02:20:35+00:00
30306,offtarget_evidence,25,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 35205363; weak/generic or abstract-limited support for seed-mediated off-target effect.,2026-06-07T02:20:35+00:00
30307,offtarget_evidence,26,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In this study, we used RNA-seq to evaluate the off-target differential splicing events of 81 SBOs and differential expression events of 46 SBOs.",2026-06-07T02:20:35+00:00
30308,offtarget_evidence,27,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Microarray analysis was performed to examine the genome-wide off-target effects of siRNAs modified with DNA, PS, 2′-OMe, and LNA (Figure 2b).",2026-06-07T02:20:35+00:00
30309,offtarget_evidence,28,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"However, the level of off-target gene regulation in both the tumor and the liver correlated with the increase in efficacy in target knockdown, unless the seed region of the siRNA was modified.",2026-06-07T02:20:35+00:00
30310,offtarget_evidence,29,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42040413; Computational/design-only siRNA specificity screen and molecular dynamics/Ago2 modeling; no primary observed off-target effect.,2026-06-07T02:20:35+00:00
30311,offtarget_evidence,30,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41732207; Study concerns intended multigene ASO silencing/on-target functional impact and design rationale; no observed unintended off-target evidence in the passage.,2026-06-07T02:20:35+00:00
30312,offtarget_evidence,31,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42170085; Aptamer-library microarray chemistry/binding study, not therapeutic ASO/siRNA off-target biology; microarray is synthesis/binding platform rather than transcriptome off-target assay.",2026-06-07T02:20:35+00:00
30313,offtarget_evidence,32,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40727077; Passage mentions potential off-target effects requiring future investigation and focuses on tumor targeting, biodistribution, toxicity, and efficacy; no observed off-target result.",2026-06-07T02:20:35+00:00
30314,offtarget_evidence,33,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C as borderline: PMID 39934917; curator counted seed-mediated off-target effect for ADO2 despite v2 exclusion. Low-confidence override; v2 note was: Observed result is allele/on-target mutant CLCN7 silencing specificity, while off-target text is background/design discussion; no measured unintended off-target effect.",2026-06-07T02:20:35+00:00
30315,offtarget_evidence,34,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40881422; Oligonucleotide-linked PROTAC control system; off-target concern is PROTAC protein degradation/toxicity, not therapeutic oligonucleotide off-target hybridization or transcriptome evidence.",2026-06-07T02:20:35+00:00
30316,offtarget_evidence,35,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37566293; Grape seed proanthocyanidin/natural product study; no therapeutic oligonucleotide in scope.,2026-06-07T02:20:35+00:00
30317,offtarget_evidence,36,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Here, we report chemistry-specific effects of oligonucleotides composed of modified or unmodified bases, with phosphorothioate linkages, on subnuclear organelles and show altered distribution of nuclear proteins, the appearance of highly stable and strikingly structured nuclear inclusions, and disturbed RNA processing in primary human fibroblasts and other cultured cells.",2026-06-07T02:20:35+00:00
30318,offtarget_evidence,37,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 31804057; Off-target effects are for small-molecule drugs/metabolomics software (metformin/etomoxir), not oligonucleotide therapeutics.",2026-06-07T02:20:35+00:00
30319,offtarget_evidence,38,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32186780; Klf15 siRNA is used as a laboratory knockdown tool in a thrombosis transcriptome study; cited ASO off-target example is not the primary evidence for this entity.,2026-06-07T02:20:35+00:00
30320,offtarget_evidence,39,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28988714; Single-stranded oligodeoxynucleotide-mediated gene repair/genome-editing donor mapping is outside therapeutic oligonucleotide off-target scope under the v2 gates.,2026-06-07T02:20:35+00:00
30321,offtarget_evidence,40,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 19854938; pmc_full_text evidence was direct but less than full primary-detail confidence for off-target evidence.,2026-06-07T02:20:35+00:00
30322,offtarget_evidence,41,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40877521; Abstract presents a structural/predictive siRNA design parameter; observed assay details are insufficient and v2 rejects computational/design-only specificity screens when unclear.,2026-06-07T02:20:35+00:00
30323,offtarget_evidence,42,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We demonstrate that knocking down AGO2, but not AGO1 or AGO4, is protective against GalNAc-siRNA-driven off-target activity and hepatotoxicity.",2026-06-07T02:20:35+00:00
30324,offtarget_evidence,43,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40877522; Methods/chapter-style strategy to reduce siRNA off-target risk by blocking strand phosphorylation; no primary observed off-target result.,2026-06-07T02:20:35+00:00
30325,offtarget_evidence,44,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We conducted ultraviolet (UV) melting experiments, RNase H cleavage assays, in vitro knockdown assays, and off-target transcriptome analyses using DNA microarrays.",2026-06-07T02:20:35+00:00
30326,offtarget_evidence,45,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37797162; Current study measures lasiRNA gene-silencing efficiency, Ago2 binding, and immune stimulation; off-target reduction is prior asiRNA background and mismatch refers target overhang design.",2026-06-07T02:20:35+00:00
30327,offtarget_evidence,46,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 36223135; previous accept was too weak/generic for seed-mediated off-target effect in unspecified siRNA. Basis checked: Abstract-only primary siRNA modification study reports measured in vitro off-target profiles for seed-region nucleotide analogues.,2026-06-07T02:20:35+00:00
30328,offtarget_evidence,47,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,METHODS: We extend recent studies by investigating the off-target profile of two 17-mer antisense oligonucleotides in two distinct human cell lines by a whole-transcriptome study using RNA sequencing.,2026-06-07T02:20:35+00:00
30329,offtarget_evidence,48,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32006400; Chapter/protocol-style strand-selection strategy; no primary observed off-target assay result in passage.,2026-06-07T02:20:35+00:00
30330,offtarget_evidence,49,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,As this change in coagulation was unrelated to FXII we conclude that it was off-target.,2026-06-07T02:20:35+00:00
30331,offtarget_evidence,50,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Transcriptome analysis indicated that nontoxic gapmers do not cleave off-target RNAs, although they have many target-like RNA sequences.",2026-06-07T02:20:35+00:00
30332,offtarget_evidence,51,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"ASO-2025-A/L downregulated 317 genes, which were confirmed by RNA-sequence analysis, the majority was involved in cell adhesion pathways downstream of ARL4C signaling, and only two genes corresponded to off-target genes.",2026-06-07T02:20:35+00:00
30333,offtarget_evidence,52,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 40185334; previous accept was too weak/generic for off-target evidence in GCD2. Basis checked: Allele-targeting GCD2 therapeutic siRNA showed measured WT TGFBI silencing in primary human corneal cells, consistent with mismatch/off-allele off-target activity; abstract-only.",2026-06-07T02:20:35+00:00
30334,offtarget_evidence,53,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 37638886; previous accept was too weak/generic for off-target evidence in Ago2. Basis checked: Therapeutic GalNAc-siRNA modification was tested in rat toxicology and reported mitigation of off-target effects; abstract-only.,2026-06-07T02:20:35+00:00
30335,offtarget_evidence,54,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 37144553; previous accept was too weak/generic for off-target evidence in Mo2; Mo3; Argonaute2. Basis checked: Therapeutic siRNA strand-bias modification was experimentally evaluated in vitro and in mice and reduced sense-strand off-target activity; abstract-only.,2026-06-07T02:20:35+00:00
30336,offtarget_evidence,55,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 34672619; previous accept was too weak/generic for off-target evidence in PDCD4. Basis checked: Circular antisense anti-miR oligonucleotides were experimentally assayed and reported reduced off-target effects as microRNA inhibitors; abstract-only and somewhat mechanistic.,2026-06-07T02:20:35+00:00
30337,offtarget_evidence,56,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Regardless of their target, phosphorothioate-modified antisense and siRNA compounds, but not oligonucleotides with a phosphodiester backbone, resulted in a similar impact on the proteome.",2026-06-07T02:20:35+00:00
30338,offtarget_evidence,57,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41730837; Passage uses siRNA as a laboratory knockdown tool to study HPV16 E7 cancer biology; transcriptome changes are on-pathway biology, not therapeutic oligo off-target evidence.",2026-06-07T02:20:35+00:00
30339,offtarget_evidence,58,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41512040; Passage describes designed triplet nucleic-acid ligands and binding selectivity/mismatch rationale, not observed unintended off-target effects of a therapeutic oligonucleotide.",2026-06-07T02:20:35+00:00
30340,offtarget_evidence,59,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Further, we demonstrate that a covalent adenosine deaminase-ASO “RNP” conjugate formed in the test tube and delivered by lipofection achieves targeted and efficient RNA editing with dramatically lower transcriptome-wide off-target editing as compared to ectopically expressed RNA editing enzymes.",2026-06-07T02:20:35+00:00
30341,offtarget_evidence,60,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To evaluate the off-target effects of GalNAc-siCIDEB, we first conducted whole-transcriptome RNA sequencing (RNA-seq) analysis in primary rat hepatocytes.",2026-06-07T02:20:35+00:00
30342,offtarget_evidence,61,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37031257; Passage concerns RNAi/shRNA regulation of AAV-delivered transgenes, which falls under the AAV/viral gene therapy and shRNA exclusion despite off-target reporter/RNA-seq assays.",2026-06-07T02:20:35+00:00
30343,offtarget_evidence,62,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 34648028; weak/generic or abstract-limited support for seed-mediated off-target effect.,2026-06-07T02:20:35+00:00
30344,offtarget_evidence,63,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Accept C as borderline: PMID 33664996; curator counted seed-mediated off-target effect for siRNAs despite v2 exclusion. Low-confidence override; v2 note was: The paper intentionally designs siRNAs to exploit tumor-suppressive miRNA-like seed activity and reports anticancer efficacy; this is not observed unintended off-target?,2026-06-07T02:20:35+00:00
30345,offtarget_evidence,64,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To determine if HTT silencing or Di-siRNA treatment had any major effect on the transcriptome, we performed genome-wide RNA sequencing (RNA-seq), comparing Di-siRNAHTT-treated to naïve NHP brains. We analyzed three cortical replicates from each of 8 animals (4 naïve, 4 treated). We chose to analyze the cortex, because we observed the highest accumulation of Di-siRNA in this region. Therefore, the chances of seeing off-target effects would be maximized.",2026-06-07T02:20:35+00:00
30346,offtarget_evidence,65,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 29390093; pmc_full_text evidence was direct but less than full primary-detail confidence for transcriptome-level off-target effect.,2026-06-07T02:20:35+00:00
30347,offtarget_evidence,66,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Furthermore, to study the underlying mechanisms of liver toxicity, we applied transcriptome profiling and pathway analyses and show that adverse in vivo liver phenotypes correlate with the number of potent, hybridization-mediated off-target effects (OTEs).",2026-06-07T02:20:35+00:00
30348,offtarget_evidence,67,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We observed highly selective transcript knockdown in mice treated with non-hepatotoxic LNA ASOs, while the levels of many unintended transcripts were reduced in mice treated with hepatotoxic LNA ASOs.",2026-06-07T02:20:35+00:00
30349,offtarget_evidence,68,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 22058018; The off-target statement refers to prior asiRNA structure work; the captured current study mainly screens and optimizes c-MET asiRNA potency, without primary observed off-target evidence.",2026-06-07T02:20:35+00:00
30350,offtarget_evidence,69,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40482915; the abstained record was checked at abstract level, but off-target evidence is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
30351,offtarget_evidence,70,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40311353; siRNA remains unsupported for off-target evidence after abstract-level review of 'Effective targeting of E2F1 transcription factor via siRNA gene electrotransfer in HT-29 color?'.,2026-06-07T02:20:35+00:00
30352,offtarget_evidence,71,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40229422; available abstract is not enough to curate transcriptome-level off-target effect for silence as a verified offtarget record.,2026-06-07T02:20:35+00:00
30353,offtarget_evidence,72,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39820813; the abstained record was checked at abstract level, but transcriptome-level off-target effect is still not directly recoverable for silencing.",2026-06-07T02:20:35+00:00
30354,offtarget_evidence,73,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In rats, off-target toxicity (not attributable to hybridization) was observed after weekly intra-abdominal administration of ASO-4733.",2026-06-07T02:20:35+00:00
30355,offtarget_evidence,74,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38369231; 'Allele-specific antisense oligonucleotides for the treatment of BEST1-related dominantly inher?' does not provide a sufficiently specific administered-oligo offtarget endpoint for single.,2026-06-07T02:20:35+00:00
30356,offtarget_evidence,75,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38945909 abstract/title reviewed; no clear in-scope transcriptome-level off-target effect endpoint is grounded for inclisiran.,2026-06-07T02:20:35+00:00
30357,offtarget_evidence,76,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37290591; single remains unsupported for seed-mediated off-target effect after abstract-level review of 'Evaluation of RNAi therapeutics VIR-2218 and ALN-HBV for chronic hepatitis B: Results from ran?'.,2026-06-07T02:20:35+00:00
30358,offtarget_evidence,77,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28274742; silencing remains unsupported for hybridization/mismatch off-target effect after abstract-level review of 'A hyaluronic acid-based hydrogel enabling CD44-mediated chondrocyte binding and gapmer oligonu?'.,2026-06-07T02:20:35+00:00
30359,offtarget_evidence,78,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Furthermore, many OffT effects observed at the RNA level do not directly translate to corresponding protein level changes.",2026-06-07T02:20:35+00:00
30360,offtarget_evidence,79,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42112101; ClinASO uses off-target filtering/prediction as a design criterion; the captured passage does not provide primary observed off-target effect evidence.,2026-06-07T02:20:35+00:00
30361,offtarget_evidence,80,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42033225; F-ASO data are target/reporter/RNA-foci efficacy and cytotoxicity; off-target effects are mentioned as prior reports for LNA, not primary observed off-target evidence here.",2026-06-07T02:20:35+00:00
30362,offtarget_evidence,81,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41611213; Passage motivates targeted delivery by possible off-target toxicity and reports loading/uptake/target knockdown, but no measured unintended off-target effect.",2026-06-07T02:20:35+00:00
30363,offtarget_evidence,82,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To assess siRNA specificity, we performed seed-based 3′UTR off-target prediction and integrated it with the RNA-seq dataset; no enrichment of predicted off-target transcripts among genes with significantly downregulated expressions was observed.",2026-06-07T02:20:35+00:00
30364,offtarget_evidence,83,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41755009; Passage reports natural-product/PD-L1 siRNA co-delivery, uptake, PD-L1 silencing, and tumor efficacy; no primary observed off-target evidence is present.",2026-06-07T02:20:35+00:00
30365,offtarget_evidence,84,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41948127; reject: AAV9-delivered miRNA/RNAi gene therapy is an explicit scope exclusion despite RNA-seq/off-target specificity assessment,2026-06-07T02:20:35+00:00
30366,offtarget_evidence,85,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41840584; reject: TCOF1 silencing uses oligonucleotide knockdown as a research tool; microarray/proteomics measure on-target biology rather than therapeutic oligo off-target effects,2026-06-07T02:20:35+00:00
30367,offtarget_evidence,86,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41932914; reject: therapeutic siRNA is in scope, but scRNA-seq describes tumor and immune efficacy/TME changes, not observed unintended off-target effects",2026-06-07T02:20:35+00:00
30368,offtarget_evidence,87,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41868107; reject: seed/off-target language is design/citation context; this primary study reports siRNA chemistry and on-target Ttr/ApoB potency, not measured unintended off-target effects",2026-06-07T02:20:35+00:00
30369,offtarget_evidence,88,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41858838; reject: therapeutic tetravalent siRNA studies S6k1 silencing, retinal efficacy, and cross-species pharmacology; no observed hybridization/mismatch off-target evidence",2026-06-07T02:20:35+00:00
30370,offtarget_evidence,89,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41709035; reject: UTMD-si-JMJD2A outcomes are target knockdown, ferroptosis, tumor growth, metastasis, and immune remodeling; no observed unintended off-target effect",2026-06-07T02:20:35+00:00
30371,offtarget_evidence,90,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41647289; reject: FGFR2 siRNA hydrogel work reports delivery, sustained release, and on-target pathway modulation; off-target evidence is absent",2026-06-07T02:20:35+00:00
30372,offtarget_evidence,91,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C as borderline: PMID 41552385; curator counted hybridization/mismatch off-target effect for siRNA despite v2 exclusion. Low-confidence override; v2 note was: reject: central mismatch/SNA assays measure allele-selective knockdown of expanded versus normal CAG targets, not unintended off-target hybridization effects",2026-06-07T02:20:35+00:00
30373,offtarget_evidence,92,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42193837; reject: TEAD4 siRNA is a porcine cell biology knockdown tool; RNA-seq measures downstream differentiation biology, not therapeutic oligo off-target effects",2026-06-07T02:20:35+00:00
30374,offtarget_evidence,93,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42182232; reject: abstract-only RNA-seq differences are not clearly grounded as siRNA off-target effects; passage frames them as model/therapy-response characterization,2026-06-07T02:20:35+00:00
30375,offtarget_evidence,94,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42164756; reject: review article/secondary summary, including computational or literature safety statements, not primary measured off-target evidence",2026-06-07T02:20:35+00:00
30376,offtarget_evidence,95,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42163396; reject: BLV miRNA polymorphism/host transcriptome biology is not a therapeutic oligonucleotide intervention,2026-06-07T02:20:35+00:00
30377,offtarget_evidence,96,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42089116; reject: independent siRNAs are used to control research-tool knockdown specificity; no observed unintended off-target effect is reported,2026-06-07T02:20:35+00:00
30378,offtarget_evidence,97,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42084802; reject: MBD2 siRNA is a mechanistic CRC research tool and KCC07 is a small molecule; outcomes are on-target pathway/efficacy, not oligo off-target evidence",2026-06-07T02:20:35+00:00
30379,offtarget_evidence,98,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42075373; reject: strawberry RNAi/overexpression study is plant/agricultural biology and outside therapeutic oligonucleotide scope,2026-06-07T02:20:35+00:00
30380,offtarget_evidence,99,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42066623; reject: intervention includes AAV-mediated shRNA knockdown and pharmacologic inhibition; shRNA/AAV gene-therapy tools are excluded and off-target effects are not oligo hybridization evidence,2026-06-07T02:20:35+00:00
30381,offtarget_evidence,100,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42015182; reject: antiviral siRNA study relies on comparative-genomics design, mismatch reporter activity, tolerability, and in silico off-target prediction rather than observed unintended transcript effects",2026-06-07T02:20:35+00:00
30382,offtarget_evidence,101,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42007882; reject: lentiviral shRNA is excluded; hepatic off-target transduction is delivery/biodistribution, not oligo sequence off-target evidence",2026-06-07T02:20:35+00:00
30383,offtarget_evidence,102,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41988374; reject: PET tracer small-molecule off-target selectivity is outside oligonucleotide scope,2026-06-07T02:20:35+00:00
30384,offtarget_evidence,103,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41878126; reject: siTGF-beta1 therapeutic delivery is in scope, but off-target language refers to tissue distribution/exposure and systemic toxicity, not sequence-mediated off-target effects",2026-06-07T02:20:35+00:00
30385,offtarget_evidence,104,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41871170; reject: Echinococcus bcat-1 RNAi is a parasite developmental knockdown tool; transcriptomics measures on-target biological consequences, not therapeutic oligo off-target effects",2026-06-07T02:20:35+00:00
30386,offtarget_evidence,105,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41752837; reject: mismatch refers to DNA/RNA mismatch repair and viral recombination review context, not oligo hybridization mismatch off-target evidence",2026-06-07T02:20:35+00:00
30387,offtarget_evidence,106,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41664057; reject: FABP4 siRNA is used to validate pharmacologic inhibition in trophoblast cells; off-target language concerns the chemical inhibitor, not observed siRNA off-target effects",2026-06-07T02:20:35+00:00
30388,offtarget_evidence,107,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41719328; reject: pheromone receptor enantiospecificity study has no therapeutic oligonucleotide or oligo off-target evidence,2026-06-07T02:20:35+00:00
30389,offtarget_evidence,108,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41715156; reject: mismatch refers to mRNA/protein discordance in endometriosis biology, not oligo hybridization mismatch or therapeutic oligo off-target effects",2026-06-07T02:20:35+00:00
30390,offtarget_evidence,109,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39850319; Reject: SGLT2 SNA-ASO is in oligo therapeutic scope, but the passage only mentions off-target effects as a general challenge/future RNA-seq need; no primary measured unintended off-target result.",2026-06-07T02:20:35+00:00
30391,offtarget_evidence,110,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41012491; Reject: the evidence concerns GalNAc-siRNA PK/biodistribution into off-target tissues and PBPK modeling, not transcriptome/seed/hybridization unintended gene off-target effects.",2026-06-07T02:20:35+00:00
30392,offtarget_evidence,111,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41210590; Reject: ASO switch is tied to synthetic mRNA therapeutics, which are excluded; observed issues are synthetic mRNA switch/reporter binding and cytotoxicity context, not in-scope therapeutic oligo off-target evidence.",2026-06-07T02:20:35+00:00
30393,offtarget_evidence,112,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41399434; Reject: WAS siRNA nanoparticle data address delivery selectivity, biodistribution, systemic toxicity, and tumor efficacy; no measured unintended sequence-dependent off-target effect.",2026-06-07T02:20:35+00:00
30394,offtarget_evidence,113,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Subsequently, the knockdown efficiency of candidate siRNAs on these potential off-target genes was individually verified through in-vitro qPCR. Most candidate siRNAs exhibited little potential off-target effects on those genes (Figures S10 and S11). However, two siRNAs, si098-DV29P and si086-DV26P, exerted relatively strong inhibition on their potential off-target genes (Figures S10B and S10E), suggesting that measures should be taken to prevent and control the off-target risk.",2026-06-07T02:20:35+00:00
30395,offtarget_evidence,114,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41463125; Reject: miRNA-targeting ASOs are evaluated for chemosensitization/efficacy and toxicity; the matched evidence is not hybridization/mismatch unintended off-target evidence.,2026-06-07T02:20:35+00:00
30396,offtarget_evidence,115,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"However, siRNA 27 treatment led to increased expression of IFIT1 (Figure 7A) and OAS1 (Figure 7B), and siRNA 30 induced elevated expression of IFIT1 (Figure 7A), OAS1 (Figure 7B), and ISG20 (Figure 7D).",2026-06-07T02:20:35+00:00
30397,offtarget_evidence,116,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"bsYW-61 reduced luciferase activity in the guide strand seed reporter, confirming seed-mediated off-target effects (Figure 6I). In contrast, modified bsYW-61m1 showed no such activity, suggesting that the chemical modification effectively abolished these interactions.",2026-06-07T02:20:35+00:00
30398,offtarget_evidence,117,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40609116; Reject: abstract-only nanoparticle targeting strategy claims reduced off-target risk but provides no primary measured unintended off-target effect.,2026-06-07T02:20:35+00:00
30399,offtarget_evidence,118,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39385468; Reject: LNP-CRISPR-Cas9 gene editing is explicitly out of scope; claimed lack of off-target effects is not therapeutic oligonucleotide off-target evidence.,2026-06-07T02:20:35+00:00
30400,offtarget_evidence,119,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40160160; Reject: first-in-human siRNA-DegradaBALL passage reports clinical safety/tolerability and PK-style safety outcomes, not measured unintended off-target transcript/effect evidence.",2026-06-07T02:20:35+00:00
30401,offtarget_evidence,120,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40547092; Reject: LyTON ASO work reports target knockdown and lack of sequence-independent off-target effects; no observed unintended off-target effect meeting the off-target accept gate.,2026-06-07T02:20:35+00:00
30402,offtarget_evidence,121,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41465224; Reject: machine-learning prediction/design paper for modified siRNA activity/off-target risk; computational/design-only specificity evidence is excluded.,2026-06-07T02:20:35+00:00
30403,offtarget_evidence,122,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40171444; Reject: potency prediction and molecular modeling of siRNA sequence positions; no primary observed seed-mediated off-target effect.,2026-06-07T02:20:35+00:00
30404,offtarget_evidence,123,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41487160; Reject: M6P-siRNA conjugate study concerns targeted delivery/uptake and efficacy, not measured unintended off-target gene effects.",2026-06-07T02:20:35+00:00
30405,offtarget_evidence,124,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41402667; Reject: aptamer-siRNA chimera evidence is target-cell delivery, CD47 silencing, biodistribution and tumor efficacy; no sequence-dependent unintended off-target result.",2026-06-07T02:20:35+00:00
30406,offtarget_evidence,125,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40761479; Reject: transcriptome/epitranscriptome data are disease mechanism and target discovery/readout for NSUN4 siRNA therapy, not transcriptome-wide oligo off-target analysis.",2026-06-07T02:20:35+00:00
30407,offtarget_evidence,126,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40598231; Reject: pH-responsive siRNA nanoparticle evidence concerns delivery specificity, biodistribution risk, and antitumor efficacy; no observed unintended off-target effect.",2026-06-07T02:20:35+00:00
30408,offtarget_evidence,127,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39632755; Reject: MYC asiRNA work mainly uses design rules, BLAST, mismatch/scramble controls, and efficacy/toxicity readouts; it does not measure a concrete unintended hybridization/mismatch off-target transcript/effect.",2026-06-07T02:20:35+00:00
30409,offtarget_evidence,128,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41594586; Reject: RNA nanoparticle study reports efficacy and absence of off-target toxicity, not observed unintended off-target gene/effect evidence.",2026-06-07T02:20:35+00:00
30410,offtarget_evidence,129,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41249187; Reject: RAF inhibitor/small-molecule study; siRNA, if present, is a lab perturbation tool rather than therapeutic oligonucleotide off-target evidence.",2026-06-07T02:20:35+00:00
30411,offtarget_evidence,130,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41163094; Reject: fish gonad-development biology/FISH probe context, not therapeutic oligonucleotide; claimed mismatch evidence is probe/design specificity, not off-target therapeutic evidence.",2026-06-07T02:20:35+00:00
30412,offtarget_evidence,131,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41048399; Reject: CRISPR-Cas13d circRNA knockdown method and circRNA biology tool are explicitly excluded; siRNA is comparator/lab tool.,2026-06-07T02:20:35+00:00
30413,offtarget_evidence,132,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41007385; Reject: dsRNA RNAi in Pomacea canaliculata pest/feeding biology is agricultural/invasive-species RNAi and explicitly out of scope.,2026-06-07T02:20:35+00:00
30414,offtarget_evidence,133,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41006213; Reject: STAR is a Cas6-CBS/CRISPR-derived transcript degrader with AAV delivery/tool context, explicitly out of scope despite transcriptome-level off-target assessment.",2026-06-07T02:20:35+00:00
30415,offtarget_evidence,134,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40944974; reject: endogenous circRNA/miRNA cancer-resistance biology with FISH/luciferase mechanistic assays; no therapeutic oligonucleotide off-target evidence,2026-06-07T02:20:35+00:00
30416,offtarget_evidence,135,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 40928446; pmc_full_text evidence was direct but less than full primary-detail confidence for transcriptome-level off-target effect.,2026-06-07T02:20:35+00:00
30417,offtarget_evidence,136,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40896585; reject: passage states general siRNA delivery limitations and target AURKA silencing; no primary observed unintended off-target result,2026-06-07T02:20:35+00:00
30418,offtarget_evidence,137,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40781069; reject: size-mismatched nanoparticles and YTHDF1 siRNA efficacy/immunotherapy readouts; mismatch does not refer to oligo hybridization and no observed off-target evidence,2026-06-07T02:20:35+00:00
30419,offtarget_evidence,138,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40762837; reject: inverted chimeric siRNAs are evaluated for KRAS/MYC target silencing and tumor efficacy; off-target silencing is only background context, not an observed result",2026-06-07T02:20:35+00:00
30420,offtarget_evidence,139,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40661947; reject: endogenous lncRNA NEAT1 biology using siRNA as a lab knockdown tool; no therapeutic oligonucleotide off-target evidence,2026-06-07T02:20:35+00:00
30421,offtarget_evidence,140,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40330464; reject: genome-wide CRISPR/Cas9 screen with siRNA validation for innate-immunity biology; CRISPR and lab knockdown context excluded,2026-06-07T02:20:35+00:00
30422,offtarget_evidence,141,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40285599; reject: SAMS siRNA payload delivery and target knockdown efficacy; no observed unintended off-target effect,2026-06-07T02:20:35+00:00
30423,offtarget_evidence,142,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40234384; reject: Zfp36 siRNA is a mechanistic lab knockdown in transplantation biology; no therapeutic oligonucleotide off-target evidence,2026-06-07T02:20:35+00:00
30424,offtarget_evidence,143,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40192175; reject: transferrin-receptor conjugate measures brain delivery/biodistribution and acute toxicity of DNA cargo; PK/biodistribution evidence is excluded,2026-06-07T02:20:35+00:00
30425,offtarget_evidence,144,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Activation of the interferon response may cause non-specific inhibition of gene expression and could explain the observed non-specific effects of in vitro transcribed pri-miR-31 sequences.,2026-06-07T02:20:35+00:00
30426,offtarget_evidence,145,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40073639; reject: chicken ovarian VLDL physiology and mipomersen used as a pharmacologic inhibitor; no therapeutic oligonucleotide off-target evidence,2026-06-07T02:20:35+00:00
30427,offtarget_evidence,146,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39900983; reject: endogenous miR-25-3p disease biology and siRNA/mimic cell tools; no therapeutic oligonucleotide off-target evidence,2026-06-07T02:20:35+00:00
30428,offtarget_evidence,147,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39472692; reject: siRNA library screen identifies METTL3 as an oxaliplatin-resistance mediator; RNA-seq/metabolomics are on-target pathway analyses, not oligo off-target evidence",2026-06-07T02:20:35+00:00
30429,offtarget_evidence,148,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40303332; reject: endothelial MYC siRNA/miR-218 nanoparticles are assessed for vessel normalization and therapy sensitization; scRNA-seq is disease-state profiling, not off-target evidence",2026-06-07T02:20:35+00:00
30430,offtarget_evidence,149,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40357997; reject: DNA nanohydrogel imaging probe hybridization/design; no therapeutic oligonucleotide administered and no off-target effect evidence,2026-06-07T02:20:35+00:00
30431,offtarget_evidence,150,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40244193; reject: prawn RNAi under alkali stress is agricultural/aquaculture biology and lab knockdown; scope exclusion applies,2026-06-07T02:20:35+00:00
30432,offtarget_evidence,151,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40171277; reject: CAG-targeted AAV-delivered shRNA therapy; shRNA and viral gene-therapy vectors are excluded,2026-06-07T02:20:35+00:00
30433,offtarget_evidence,152,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39990870; reject: COP1 siRNAs are cell-biology knockdown tools; microarray/transcriptome changes reflect COP1 suppression biology, not unintended oligo off-target effects",2026-06-07T02:20:35+00:00
30434,offtarget_evidence,153,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39011883; reject: R-ASO study evaluates target-specific nonsense readthrough and on-target specificity; off-target translation errors are background concern, not measured unintended oligo off-target evidence",2026-06-07T02:20:35+00:00
30435,offtarget_evidence,154,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39494149; reject: ASO-RNA complexation article uses molecular dynamics/design simulations; computational/design-only evidence is excluded,2026-06-07T02:20:35+00:00
30436,offtarget_evidence,155,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39377066; reject: REST_SSO is tested for target splicing, tumor efficacy, and hepatotoxicity; no observed off-target hybridization or transcriptome result",2026-06-07T02:20:35+00:00
30438,offtarget_evidence,157,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To determine whether combination treatment exacerbates the off-target effects of the individual compounds, we performed RNA-Seq on transcripts isolated from cells treated with LoA + R and LoA + B (Figure 2A and B).",2026-06-07T02:20:35+00:00
30439,offtarget_evidence,158,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38214218; reject: albumin-ASO assembly is evaluated for release, trafficking, recycling, and ADAMTS5 target silencing; no observed off-target effect",2026-06-07T02:20:35+00:00
30440,offtarget_evidence,159,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39321261; reject: computational siRNA design/prediction pipeline; off-target effects are predicted/screened, not observed unintended effects",2026-06-07T02:20:35+00:00
30441,offtarget_evidence,160,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39189114; reject: mismatch conversion assesses cross-species target knockdown potency/efficacy, not unintended off-target effects",2026-06-07T02:20:35+00:00
30442,offtarget_evidence,161,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39066234; reject: SARS-CoV-2 siRNAs were screened for predicted off-target effects and tested for antiviral efficacy; no observed unintended off-target result,2026-06-07T02:20:35+00:00
30443,offtarget_evidence,162,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38521952; reject: bacterial shRNA/RNAi delivery platform and tumor efficacy; shRNA is excluded and no observed oligo off-target evidence,2026-06-07T02:20:35+00:00
30444,offtarget_evidence,163,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38304729; reject: multispecies JAK1 siRNAs are evaluated for target silencing/cross-reactive efficacy and design filtering, not observed unintended off-target effects",2026-06-07T02:20:35+00:00
30445,offtarget_evidence,164,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The in silico predictions were confirmed experimentally in CD3/CD28 bead-activated human pan T cells, where no off-target silencing GRAMD4 mRNA was observed, such that an IC50 for PH-762 toward GRAMD4 mRNA could not be determined",2026-06-07T02:20:35+00:00
30446,offtarget_evidence,165,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38750585; reject: BPA transcriptomics and siRNA-mediated Sema5a knockdown as a lab tool; no therapeutic oligonucleotide off-target evidence,2026-06-07T02:20:35+00:00
30447,offtarget_evidence,166,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38570783; reject: siRNA is used as an RNAi knockdown tool in Sertoli-cell biology/toxicant injury models, not as therapeutic off-target evidence",2026-06-07T02:20:35+00:00
30448,offtarget_evidence,167,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38402402; reject: CRISPR screen and apatinib small-molecule off-target biology; siRNA appears only as a lab knockdown reagent,2026-06-07T02:20:35+00:00
30449,offtarget_evidence,168,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38291540; reject: glioblastoma pathway study uses small-molecule GPR68 inhibitor plus siRNA/CRISPRi lab tools; off-target refers to lorazepam/GPR68, not oligo hybridization",2026-06-07T02:20:35+00:00
30450,offtarget_evidence,169,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39719436; reject: cancer radioresistance genomic/transcriptomic profiling and BAHD1 knockdown tool; mismatch refers to DNA repair signatures, not oligo off-target effects",2026-06-07T02:20:35+00:00
30451,offtarget_evidence,170,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39611095; reject: Dicer-substrate siRNA swarms are tested for antiviral efficacy; off-target risk is discussed as background/rationale, not an observed unintended effect",2026-06-07T02:20:35+00:00
30452,offtarget_evidence,171,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39233852; reject: C9ORF72 siRNAs are evaluated for selective/non-selective target transcript knockdown and disease modification; specificity was not assessed as unintended off-target evidence,2026-06-07T02:20:35+00:00
30453,offtarget_evidence,172,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39088581; reject: eNOS-siRNA study measures delivery/transfection and anti-angiogenic target knockdown efficacy; off-target appears as general specificity rationale,2026-06-07T02:20:35+00:00
30454,offtarget_evidence,173,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37834294; reject: LNA gapmer off-target assessment is database/in silico searching; mismatch experiments support sequence-dependent antiviral on-target mechanism,2026-06-07T02:20:35+00:00
30455,offtarget_evidence,174,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36576986; reject: hERG assay uses anti-hERG siRNA as a time-dependent positive-control model for safety profiling, not observed unintended off-target evidence for a therapeutic oligo",2026-06-07T02:20:35+00:00
30456,offtarget_evidence,175,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38087193; reject: in silico siRNA design/validation pipeline; no administered or observed off-target result,2026-06-07T02:20:35+00:00
30457,offtarget_evidence,176,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37925520; reject: JAK1 siRNA selectivity against JAK family members measures intended target specificity/signaling efficacy, not unintended siRNA off-target evidence",2026-06-07T02:20:35+00:00
30458,offtarget_evidence,177,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37224533; reject: antibody-oligonucleotide conjugate study reports tissue delivery, PK/PD, and target silencing controls, not observed off-target effects",2026-06-07T02:20:35+00:00
30459,offtarget_evidence,178,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37016578; reject: RBCEV siRNA delivery reports target inhibition, cachexia efficacy, and non-inflammatory safety; no observed unintended off-target result",2026-06-07T02:20:35+00:00
30460,offtarget_evidence,179,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36342214; reject: endogenous plant cis-antisense RNA/RNAi biology is outside therapeutic oligonucleotide scope,2026-06-07T02:20:35+00:00
30461,offtarget_evidence,180,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38095348; reject: Bmi-1 RNAi/PTX nanoparticle cancer-cell/tumor efficacy; off-target is a delivery rationale, not an observed unintended effect",2026-06-07T02:20:35+00:00
30462,offtarget_evidence,181,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37901602; reject: Drosophila targeted RNAi screen uses RNAi as a lab knockdown tool; no therapeutic oligonucleotide off-target evidence,2026-06-07T02:20:35+00:00
30463,offtarget_evidence,182,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37745037; reject: endogenous lncRNA/miRNA cervical-cancer biology; siRNA/ASO are transfection tools, outside therapeutic oligo scope",2026-06-07T02:20:35+00:00
30464,offtarget_evidence,183,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37724723; reject: nusinersen is in-scope but the reported minimal off-target transcriptomics concern MS023 PRMT-inhibitor treatment/synergy, not observed oligo off-target evidence",2026-06-07T02:20:35+00:00
30465,offtarget_evidence,184,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37667354; siRNA is used as a laboratory knockdown/rescue tool for chemoresistance, not a therapeutic oligo off-target result.",2026-06-07T02:20:35+00:00
30466,offtarget_evidence,185,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37552050; ARTi shRNAmir is a loss-of-function target-validation tool; passage discusses engineered shRNA controls, not therapeutic oligo off-target evidence.",2026-06-07T02:20:35+00:00
30467,offtarget_evidence,186,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37432453; Plant/rhizobial symbiosis RNAi knockdown study; agricultural/plant biology and lab knockdown tool are out of scope.,2026-06-07T02:20:35+00:00
30468,offtarget_evidence,187,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37274069; Calcitriol small-molecule liver fibrosis study with siRNA/plasmid mechanistic tools; no therapeutic oligo off-target evidence.,2026-06-07T02:20:35+00:00
30469,offtarget_evidence,188,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Also, they could interact with other mRNAs via imperfect matches (such as GAS2, POLA2, and LGALS2), thereby downregulating the expression of the related proteins and jointly inducing the apoptotic process of tumor cells (Table S4).",2026-06-07T02:20:35+00:00
30470,offtarget_evidence,189,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36831000; miR-29a antagonist was delivered by lentiviral vector as proof-of-concept; passage reports efficacy/toxicity, not unintended off-target evidence.",2026-06-07T02:20:35+00:00
30471,offtarget_evidence,190,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"As the RNA-seq results demonstrated, the off-target rate of si-S1A3-Chol was less than that of naked siRNA, which usually ranges from 5% to 80%.",2026-06-07T02:20:35+00:00
30472,offtarget_evidence,191,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35917865; Passage is about siRNA conjugate endosomal escape, tissue distribution, efficacy, and toxicity; no observed unintended sequence off-target evidence.",2026-06-07T02:20:35+00:00
30473,offtarget_evidence,192,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35737426; SLN360 passage reports no relevant off-target effects and design filtering; absence/design specificity is not observed unintended off-target evidence.,2026-06-07T02:20:35+00:00
30474,offtarget_evidence,193,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->C: PMID 36511872; weak/generic or abstract-limited support for transcriptome-level off-target effect.,2026-06-07T02:20:35+00:00
30475,offtarget_evidence,194,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35795486; Study evaluates PK-modifying anchors, clearance, tissue distribution, and efficacy; off-target claim is not supported.",2026-06-07T02:20:35+00:00
30476,offtarget_evidence,195,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34743371; Vivo-Morpholino is used for target knockdown in a disease mechanism study; passage reports on-target phenotype, not unintended off-target evidence.",2026-06-07T02:20:35+00:00
30477,offtarget_evidence,196,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34683974; Passage discusses leukemia-cell specificity and lack of healthy-cell toxicity, not experimentally observed siRNA off-target effects.",2026-06-07T02:20:35+00:00
30478,offtarget_evidence,197,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33738134; CAG-siRNA passage concerns allele/on-target selectivity and toxicity risk from normal CAG silencing; no observed unintended off-target result is grounded.,2026-06-07T02:20:35+00:00
30479,offtarget_evidence,198,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34712254; RNAi-mediated virus resistance in plum is an agricultural crop study and explicitly out of scope.,2026-06-07T02:20:35+00:00
30480,offtarget_evidence,199,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34959463; Passage addresses tumor-targeted siRNA delivery and generic carrier off-target/toxicity concerns, not observed unintended sequence off-target evidence.",2026-06-07T02:20:35+00:00
30481,offtarget_evidence,200,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34918046; Self-assembled siRNA is expressed from a genetic circuit/plasmid delivery system; cited evidence is delivery/localization, not off-target.",2026-06-07T02:20:35+00:00
30482,offtarget_evidence,201,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The off-target activities of the parent duplex and the modified duplexes were similar (Figure 5B).,2026-06-07T02:20:35+00:00
30483,offtarget_evidence,202,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33068777; Therapeutic DUX4 gapmer passage reports minimal off-target activity, i.e. absence of observed unintended off-target evidence.",2026-06-07T02:20:35+00:00
30484,offtarget_evidence,203,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34172725; RNAi prodrug system is designed to eliminate non-specific off-target effects; passage does not ground observed unintended off-target evidence.,2026-06-07T02:20:35+00:00
30485,offtarget_evidence,204,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34508350; sciRNA passage reports off-target effects were eliminated, which is absence/reduction rather than observed unintended off-target evidence.",2026-06-07T02:20:35+00:00
30486,offtarget_evidence,205,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33742144; Doxycycline-inducible shRNA is a laboratory suppression tool in cancer models; no therapeutic oligo off-target result.,2026-06-07T02:20:35+00:00
30487,offtarget_evidence,206,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32127464; Off-target toxicity belongs to small-molecule mithramycin; siRNA appears only as a screening tool.,2026-06-07T02:20:35+00:00
30488,offtarget_evidence,207,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"RNA-seq analysis of gWAT showed a widespread increase in type I interferon (IFN)-responsive genes, and knockout of the IFN receptor abolished the weight loss phenotype induced by the T39 ASO.",2026-06-07T02:20:35+00:00
30489,offtarget_evidence,208,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32153567; GalNAc-siRNA passage reports specific silencing and no significant off-target effect, not observed unintended off-target evidence.",2026-06-07T02:20:35+00:00
30490,offtarget_evidence,209,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32990754; Reject: passage only gives a general background claim that chemical modifications can reduce siRNA off-target effects; no primary measured unintended off-target result for the studied siRNAs.,2026-06-07T02:20:35+00:00
30491,offtarget_evidence,210,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33060681; Reject: source passage concerns small-molecule SMN2 splicing modulators and their secondary splice targets, not therapeutic oligonucleotide off-target evidence; nusinersen is background only.",2026-06-07T02:20:35+00:00
30492,offtarget_evidence,211,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32142732; Reject: H2HR vivo-morpholino is administered in a disease model, but the passage uses mismatch morpholino as a control and reports liver/biliary outcomes, not unintended off-target evidence.",2026-06-07T02:20:35+00:00
30493,offtarget_evidence,212,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30622178; Reject: mesyl phosphoramidate anti-miR-21 data address target affinity, specificity, RNase H activity, toxicity, and antitumor phenotypes; no concrete unintended off-target transcript/effect is measured.",2026-06-07T02:20:35+00:00
30494,offtarget_evidence,213,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30940496; Reject: evidence is siRNA pharmacokinetics, tissue distribution, and productive target silencing; PK/biodistribution and tissue accumulation are explicitly excluded from off-target curation.",2026-06-07T02:20:35+00:00
30495,offtarget_evidence,214,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30544191; Reject: lipid-conjugated siRNA study measures extrahepatic delivery, tissue distribution, and target knockdown; no observed unintended sequence-dependent off-target effect.",2026-06-07T02:20:35+00:00
30496,offtarget_evidence,215,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30097810; Reject: CMTM4/CMTM3 siRNAs are laboratory knockdown tools in angiogenesis biology, not therapeutic oligos; transcriptome text is target discovery, not siRNA off-target analysis.",2026-06-07T02:20:35+00:00
30497,offtarget_evidence,216,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30112821; Reject: LNP study evaluates delivery potency and reporter knockdown/toxicity; off-target is only a general delivery challenge, not a measured unintended off-target result.",2026-06-07T02:20:35+00:00
30498,offtarget_evidence,217,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We also performed RNA-sequencing (RNA-seq) to complement this sequence homology-based study with an unbiased approach and identify other potential hybridization-dependent off-targets. Transcriptome analysis was performed to assess the hybridization-dependent off-target effects using two untreated and two 1 μM QR-110-treated LCA10 retinal organoids. This dose was selected because it was effective at suppressing exon X (Figure 3), suggesting effective hybridization and blocking activity, but it did not significantly increase CEP290 26-27 mRNA (Figure 3F). Therefore, increased levels of CEP290 mRNA, such as those observed at higher concentrations of QR-110, which could have wider, downstream “on-target” effects, would not confound the identification of genuine “off-target” effects. Using a 2-fold change as a cutoff, 44 differentially expressed genes were identified, but none has complementarity to QR-110 (Table S8). This number of differential genes in QR-110-treated organoids is similar to transcriptome changes observed for other antisense oligonucleotides and small-molecule drugs.27 Importantly, none of the seven downregulated genes have been associated with retinal dysfunction. In combination with the selected gene analyses, these data suggest QR-110 does not have any major off-target activity.",2026-06-07T02:20:35+00:00
30499,offtarget_evidence,218,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 28123102; Reject: minipig SSO safety paper reports general toxicology, target organ findings, and absence of new off-target toxicities; no observed sequence-dependent transcript/gene off-target evidence.",2026-06-07T02:20:35+00:00
30500,offtarget_evidence,219,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28062574; Reject: endogenous miR-9/GALNT4 hepatocellular carcinoma biology and prognostic signature; no therapeutic oligo under study and no oligo off-target evidence.,2026-06-07T02:20:35+00:00
30501,offtarget_evidence,220,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Microarray analysis revealed that several pre-mRNAs containing a sequence similar to the gapmer target were also knocked down. These results suggest that hepatotoxicity of LNA gapmer is caused by RNAseH1 activity, presumably because of off-target cleavage of RNAs inside nuclei.",2026-06-07T02:20:35+00:00
30502,offtarget_evidence,221,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 27327137; Reject: LNA-i-miR-221 passage concerns PK/PD, tissue uptake by in situ hybridization, biodistribution, target upregulation, and toxicity; not unintended off-target evidence.",2026-06-07T02:20:35+00:00
30503,offtarget_evidence,222,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"RNA-seq analysis of FM10 myotube cultures from the two unaffected first-degree relatives provides another view of off-target effects, unclouded by DUX4 target genes, as unaffected cells express little if any DUX4-fl. For these cells, only three genes differed significantly between FM10 and the control PMO (P-value < 10–4), and this is roughly what one expects by chance when testing ~37,000 genes for differential expression, even if the null hypotheses of equal expression are all true (Figure 2c). No genes had P-value < 10−5 or false discovery rate < 0.72. Thus we observed no clear off-target effects of FM10 based on these samples.",2026-06-07T02:20:35+00:00
30504,offtarget_evidence,223,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 25453815; Reject: PEG-conjugated oligonucleotide work measures antisense potency/reporter activity and toxicity; no observed unintended off-target transcript/effect.,2026-06-07T02:20:35+00:00
30505,offtarget_evidence,224,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 23982190; Reject: ZEN anti-miRNA study tests potency and intentional mismatch discrimination in reporter assays; this is design/specificity optimization, not an observed unintended off-target effect.",2026-06-07T02:20:35+00:00
30506,offtarget_evidence,225,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 22615794; Reject: single-strand oligonucleotides are used for genome targeting/gene editing in cells, not therapeutic oligo administration; RNA-seq concerns cellular immunity/toxicity after gene targeting.",2026-06-07T02:20:35+00:00
30507,offtarget_evidence,226,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41863245; Reject: review article/abstract summarizing ASO challenges; no primary observed administered/measured off-target result.,2026-06-07T02:20:35+00:00
30508,offtarget_evidence,227,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41711123; no source passage or abstract wording gives a dependable offtarget call for situ.,2026-06-07T02:20:35+00:00
30509,offtarget_evidence,228,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42102394; Reject: off-target inhibition is caused by anthracycline small-molecule chemotherapy; TOP2B ASO is a proposed protective intervention, not the source of off-target evidence.",2026-06-07T02:20:35+00:00
30510,offtarget_evidence,229,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"However, the MC3-based LNP-siRNA (MC3 LNP-siRNA) treatment elicited the least off-target immune activation, with no induction of interferon stimulated genes. Additionally, the MC3 LNP-siRNA remained effective when administered 24 h post-infection, significantly reducing viral RNA levels in vitro. Chemical modification of siRNA with 2'‑O‑methyl incorporation further attenuated immune activation, without compromising efficacy.",2026-06-07T02:20:35+00:00
30511,offtarget_evidence,230,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42085538; Reject: siRNA platform is used as an alternative to a small-molecule PP2A inhibitor with off-target effects; no siRNA unintended off-target result is reported.,2026-06-07T02:20:35+00:00
30512,offtarget_evidence,231,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42097228 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
30513,offtarget_evidence,232,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42036903; no source passage or abstract wording gives a dependable offtarget call for patisiran.,2026-06-07T02:20:35+00:00
30514,offtarget_evidence,233,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41612090; siRNAs remains unsupported for hybridization/mismatch off-target effect after abstract-level review of 'Industry Practices in Oligonucleotide Tissue Biodistribution Assessment: An IQ consortium Cros?'.,2026-06-07T02:20:35+00:00
30515,offtarget_evidence,234,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41919735; Reject: DNA tetrahedron carries alpha-tocopherol for cancer cytotoxicity; off-target refers to poor drug specificity/chemotherapy delivery, not therapeutic antisense/siRNA off-target evidence.",2026-06-07T02:20:35+00:00
30516,offtarget_evidence,235,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41832714; no source passage or abstract wording gives a dependable offtarget call for siRNA-Loaded.,2026-06-07T02:20:35+00:00
30517,offtarget_evidence,236,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41437666; no source passage or abstract wording gives a dependable offtarget call for site-specific.,2026-06-07T02:20:35+00:00
30518,offtarget_evidence,237,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42154661; 'Myocardial YBX1 is dispensable for cardiac development and function.' does not provide a sufficiently specific administered-oligo offtarget endpoint for YBX1.,2026-06-07T02:20:35+00:00
30519,offtarget_evidence,238,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42119979; available abstract is not enough to curate transcriptome-level off-target effect for situ as a verified offtarget record.,2026-06-07T02:20:35+00:00
30520,offtarget_evidence,239,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42118205; 'Formation and cellular uptake of Bleomycin saccharide decorated molecular spherical nucleic ac?' does not provide a sufficiently specific administered-oligo offtarget endpoint for significant.,2026-06-07T02:20:35+00:00
30521,offtarget_evidence,240,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42105839; no source passage or abstract wording gives a dependable offtarget call for Since.,2026-06-07T02:20:35+00:00
30522,offtarget_evidence,241,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42090086; 'Exosomal circVANGL1 promotes cisplatin resistance in osteosarcoma cells by regulating the miR-?' does not provide a sufficiently specific administered-oligo offtarget endpoint for significant.,2026-06-07T02:20:35+00:00
30523,offtarget_evidence,242,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42061632; significantly remains unsupported for hybridization/mismatch off-target effect after abstract-level review of 'Identification of the inhibitors of apoptosis proteins (IAPs) gene family in Portunus trituber?'.,2026-06-07T02:20:35+00:00
30524,offtarget_evidence,243,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41962054; siRNA remains unsupported for hybridization/mismatch off-target effect after abstract-level review of 'DDR1 Promotes Immune Evasion in Colorectal Cancer by Orchestrating IL-33-Mediated M2-like Pola?'.,2026-06-07T02:20:35+00:00
30525,offtarget_evidence,244,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41838744; available abstract is not enough to curate off-target evidence for single as a verified offtarget record.,2026-06-07T02:20:35+00:00
30526,offtarget_evidence,245,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41783937; Reject: siAURKB nanocarrier study reports delivery, target silencing, tumor inhibition, and biocompatibility; off-target toxicity is background about conventional therapy only.",2026-06-07T02:20:35+00:00
30527,offtarget_evidence,246,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41747415; Reject: colorectal cancer prognostic signature and IL20RB siRNA lab knockdown assays; mismatch refers dMMR/MSI status, not oligo hybridization off-target.",2026-06-07T02:20:35+00:00
30528,offtarget_evidence,247,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41605397; available abstract is not enough to curate transcriptome-level off-target effect for situ as a verified offtarget record.,2026-06-07T02:20:35+00:00
30529,offtarget_evidence,248,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41468644; no source passage or abstract wording gives a dependable offtarget call for siRNA.,2026-06-07T02:20:35+00:00
30530,offtarget_evidence,249,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41344487; simultaneously remains unsupported for off-target evidence after abstract-level review of 'Immunological conversion of triple-negative breast cancer by engineered extracellular vesicle-?'.,2026-06-07T02:20:35+00:00
30531,offtarget_evidence,250,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41297216; the abstained record was checked at abstract level, but transcriptome-level off-target effect is still not directly recoverable for situ.",2026-06-07T02:20:35+00:00
30532,offtarget_evidence,251,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41221596; unspecified CpG oligodeoxynucleotide remains unsupported for hybridization/mismatch off-target effect after abstract-level review of 'Development of a whole cell vaccine to activate dendritic cells using polyvalent CpG.'.,2026-06-07T02:20:35+00:00
30533,offtarget_evidence,252,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41167182; no source passage or abstract wording gives a dependable offtarget call for single.,2026-06-07T02:20:35+00:00
30534,offtarget_evidence,253,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36786145; signaling remains unsupported for off-target evidence after abstract-level review of 'Targeting SHP2 Reverses BRAF Inhibitor Tolerance in Anaplastic Thyroid Carcinoma.'.,2026-06-07T02:20:35+00:00
30535,offtarget_evidence,254,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41545031; no source passage or abstract wording gives a dependable offtarget call for signaling.,2026-06-07T02:20:35+00:00
30536,offtarget_evidence,255,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40946728; no source passage or abstract wording gives a dependable offtarget call for silencing.,2026-06-07T02:20:35+00:00
30537,offtarget_evidence,256,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40699429; available abstract is not enough to curate off-target evidence for situ as a verified offtarget record.,2026-06-07T02:20:35+00:00
30538,offtarget_evidence,257,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40540297; Reject: TGF-beta1 ASO polyplex evidence is sentinel lymph node delivery and reduced off-target organ distribution, which is PK/biodistribution and explicitly excluded.",2026-06-07T02:20:35+00:00
30539,offtarget_evidence,258,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39937881; the abstained record was checked at abstract level, but transcriptome-level off-target effect is still not directly recoverable for after ASO.",2026-06-07T02:20:35+00:00
30540,offtarget_evidence,259,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39882764; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for site.",2026-06-07T02:20:35+00:00
30541,offtarget_evidence,260,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40912822; Passage concerns an aminated chitosan quinoline Schiff base, docking simulations, antibacterial activity, and toxicity prediction; it is not a therapeutic oligonucleotide off-target result.",2026-06-07T02:20:35+00:00
30542,offtarget_evidence,261,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40960849; Passage describes kidney-targeting peptide conjugation, biodistribution, and intended HIF-1alpha repression; off-target interactions are background rationale, not observed unintended oligo off-target evidence.",2026-06-07T02:20:35+00:00
30543,offtarget_evidence,262,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39631700; Passage evaluates LNP delivery and undesired hepatic transfection/retention, including mRNA delivery; it does not show seed-, mismatch-, or transcriptome-level unintended off-target effects of a therapeutic oligo.",2026-06-07T02:20:35+00:00
30544,offtarget_evidence,263,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41340590; Passage studies endogenous circ-RNF216 biology using shRNA knockdown and RNA sequencing; this is disease-mechanism biology, not therapeutic oligo off-target evidence.",2026-06-07T02:20:35+00:00
30545,offtarget_evidence,264,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41398520; available abstract is not enough to curate off-target evidence for signaling-particularly as a verified offtarget record.,2026-06-07T02:20:35+00:00
30546,offtarget_evidence,265,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40482891 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for siRNA-treated.,2026-06-07T02:20:35+00:00
30547,offtarget_evidence,266,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40163299; siRNA remains unsupported for off-target evidence after abstract-level review of 'A Robust siRNA Screening Approach with Optimized Conditions for Large-Scale Transfection in Mu?'.,2026-06-07T02:20:35+00:00
30548,offtarget_evidence,267,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40024424; no source passage or abstract wording gives a dependable offtarget call for siRNA.,2026-06-07T02:20:35+00:00
30549,offtarget_evidence,268,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39798472; the abstained record was checked at abstract level, but off-target evidence is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
30550,offtarget_evidence,269,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41249096 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for significant.,2026-06-07T02:20:35+00:00
30551,offtarget_evidence,270,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41094015; 'Staple oligomers induce a stable RNA G-quadruplex structure for protein translation inhibition?' does not provide a sufficiently specific administered-oligo offtarget endpoint for silencing.,2026-06-07T02:20:35+00:00
30552,offtarget_evidence,271,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41093250; 'Comparative analysis of antibody-mediated loss-of-function versus gene knock-out and knock-dow?' does not provide a sufficiently specific administered-oligo offtarget endpoint for siRNAs.,2026-06-07T02:20:35+00:00
30553,offtarget_evidence,272,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40840014 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for situ.,2026-06-07T02:20:35+00:00
30554,offtarget_evidence,273,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40812551; available abstract is not enough to curate hybridization/mismatch off-target effect for significant as a verified offtarget record.,2026-06-07T02:20:35+00:00
30555,offtarget_evidence,274,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40785358; significantly remains unsupported for off-target evidence after abstract-level review of 'CmPLL16a and CmPLL16b Regulate Cell Wall Remodelling and Somatic Embryogenesis in Castanea mol?'.,2026-06-07T02:20:35+00:00
30556,offtarget_evidence,275,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for transcriptome-level off-target effect in nusinersen; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30557,offtarget_evidence,276,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 29718312; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for sli-siRNA.",2026-06-07T02:20:35+00:00
30558,offtarget_evidence,277,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28542329; available abstract is not enough to curate off-target evidence for CCR5 siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30559,offtarget_evidence,278,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 27387838; 'Structure-Guided Control of siRNA Off-Target Effects.' does not provide a sufficiently specific administered-oligo offtarget endpoint for hAgo2-siRNA.,2026-06-07T02:20:35+00:00
30560,offtarget_evidence,279,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26625198; 'Apoptosis induced by a HIPK2 full-length-specific siRNA is due to off-target effects rather th?' does not provide a sufficiently specific administered-oligo offtarget endpoint for e8-siRNA.,2026-06-07T02:20:35+00:00
30561,offtarget_evidence,280,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 26041815; the abstained record was checked at abstract level, but seed-mediated off-target effect is still not directly recoverable for DICER siRNA.",2026-06-07T02:20:35+00:00
30562,offtarget_evidence,281,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for seed-mediated off-target effect in bulge-siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30563,offtarget_evidence,282,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 19521552; 'Silencing of P2Y2 receptor delays Ap4A-corneal re-epithelialization process.' does not provide a sufficiently specific administered-oligo offtarget endpoint for P2Y siRNA.,2026-06-07T02:20:35+00:00
30564,offtarget_evidence,283,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 18577207; available abstract is not enough to curate transcriptome-level off-target effect for GFP siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30565,offtarget_evidence,284,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 18096615; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for TNFR1 siRNA.",2026-06-07T02:20:35+00:00
30566,offtarget_evidence,285,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 15781493; no source passage or abstract wording gives a dependable offtarget call for siCD46.,2026-06-07T02:20:35+00:00
30567,offtarget_evidence,286,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 31509065; the abstained record was checked at abstract level, but off-target evidence is still not directly recoverable for MED-siRNA.",2026-06-07T02:20:35+00:00
30568,offtarget_evidence,287,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32738016; no source passage or abstract wording gives a dependable offtarget call for HBV siRNA.,2026-06-07T02:20:35+00:00
30569,offtarget_evidence,288,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 27033537 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for SNCG siRNA.,2026-06-07T02:20:35+00:00
30570,offtarget_evidence,289,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23027045; no source passage or abstract wording gives a dependable offtarget call for siDirect2.,2026-06-07T02:20:35+00:00
30571,offtarget_evidence,290,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23682837; available abstract is not enough to curate off-target evidence for siMek1s as a verified offtarget record.,2026-06-07T02:20:35+00:00
30572,offtarget_evidence,291,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22612256 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for EGFP siRNA.,2026-06-07T02:20:35+00:00
30573,offtarget_evidence,292,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22304497; available abstract is not enough to curate hybridization/mismatch off-target effect for RTP801 siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30574,offtarget_evidence,293,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 21028964; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for fork-siRNA.",2026-06-07T02:20:35+00:00
30575,offtarget_evidence,294,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 15737617; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for fork-siRNA.",2026-06-07T02:20:35+00:00
30576,offtarget_evidence,295,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37272117; no source passage or abstract wording gives a dependable offtarget call for SARS- siRNA.,2026-06-07T02:20:35+00:00
30577,offtarget_evidence,296,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38203580; PE- siRNA remains unsupported for seed-mediated off-target effect after abstract-level review of 'YB-1 Is a Novel Target for the Inhibition of α-Adrenergic-Induced Hypertrophy.'.,2026-06-07T02:20:35+00:00
30578,offtarget_evidence,297,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34703654; no source passage or abstract wording gives a dependable offtarget call for SNRPD3 siRNA.,2026-06-07T02:20:35+00:00
30579,offtarget_evidence,298,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34095140; PCBP2 siRNA remains unsupported for transcriptome-level off-target effect after abstract-level review of 'Knockdown of Splicing Complex Protein PCBP2 Reduces Extravillous Trophoblast Differentiation T?'.,2026-06-07T02:20:35+00:00
30580,offtarget_evidence,299,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31416840; available abstract is not enough to curate off-target evidence for INCENP siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30581,offtarget_evidence,300,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 27441640; the abstained record was checked at abstract level, but off-target evidence is still not directly recoverable for HCV siRNA.",2026-06-07T02:20:35+00:00
30582,offtarget_evidence,301,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 27306408 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for dicer-substrate-siRNA.,2026-06-07T02:20:35+00:00
30583,offtarget_evidence,302,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26516083; 'Properties of short double-stranded RNAs carrying randomized base pairs: toward better control?' does not provide a sufficiently specific administered-oligo offtarget endpoint for rnd-siRNA.,2026-06-07T02:20:35+00:00
30584,offtarget_evidence,303,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 25100204 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for RAS siRNA.,2026-06-07T02:20:35+00:00
30585,offtarget_evidence,304,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 25157820; Peptide-siRNA remains unsupported for off-target evidence after abstract-level review of 'Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthriti?'.,2026-06-07T02:20:35+00:00
30586,offtarget_evidence,305,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22939619; no source passage or abstract wording gives a dependable offtarget call for ss-siRNA.,2026-06-07T02:20:35+00:00
30587,offtarget_evidence,306,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22761791 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for PARP1 siRNA.,2026-06-07T02:20:35+00:00
30588,offtarget_evidence,307,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 21284875; NET1 siRNA remains unsupported for transcriptome-level off-target effect after abstract-level review of 'A functional and transcriptomic analysis of NET1 bioactivity in gastric cancer.'.,2026-06-07T02:20:35+00:00
30589,offtarget_evidence,308,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 21249171; 'Cellular SNF2H chromatin-remodeling factor promotes herpes simplex virus 1 immediate-early gen?' does not provide a sufficiently specific administered-oligo offtarget endpoint for SNF2H siRNA.,2026-06-07T02:20:35+00:00
30590,offtarget_evidence,309,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 20885450 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for E6 siRNA.,2026-06-07T02:20:35+00:00
30591,offtarget_evidence,310,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 20333451; RANK siRNA remains unsupported for off-target evidence after abstract-level review of 'siRNA knock-down of RANK signaling to control osteoclast-mediated bone resorption.'.,2026-06-07T02:20:35+00:00
30592,offtarget_evidence,311,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 19185544 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for NR1 siRNA.,2026-06-07T02:20:35+00:00
30593,offtarget_evidence,312,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 19919690; the abstained record was checked at abstract level, but off-target evidence is still not directly recoverable for MEK siRNA.",2026-06-07T02:20:35+00:00
30594,offtarget_evidence,313,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 19430205; available abstract is not enough to curate off-target evidence for short ASO as a verified offtarget record.,2026-06-07T02:20:35+00:00
30595,offtarget_evidence,314,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 18378325; HBV siRNA remains unsupported for off-target evidence after abstract-level review of 'Inhibition of hepatitis B virus gene expression and replication by endoribonuclease-prepared s?'.,2026-06-07T02:20:35+00:00
30596,offtarget_evidence,315,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 16439544; available abstract is not enough to curate hybridization/mismatch off-target effect for LEDGF siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30597,offtarget_evidence,316,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 15681418; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for siRNA-4.",2026-06-07T02:20:35+00:00
30598,offtarget_evidence,317,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36039858; apoCIII-siRNA remains unsupported for off-target evidence after abstract-level review of 'Treatment of the metabolic syndrome by siRNA targeting apolipoprotein CIII.'.,2026-06-07T02:20:35+00:00
30599,offtarget_evidence,318,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37478121; no source passage or abstract wording gives a dependable offtarget call for siRNA-7.,2026-06-07T02:20:35+00:00
30600,offtarget_evidence,319,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29326440; available abstract is not enough to curate off-target evidence for BRAFV600E siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30601,offtarget_evidence,320,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22921338; available abstract is not enough to curate off-target evidence for EV siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30602,offtarget_evidence,321,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 21362317; available abstract is not enough to curate hybridization/mismatch off-target effect for ALS- siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30603,offtarget_evidence,322,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 18839783; available abstract is not enough to curate hybridization/mismatch off-target effect for siRNA45 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30604,offtarget_evidence,323,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 17316836; 'Enhanced potency and efficacy of 29-mer shRNAs in inhibition of Enterovirus 71.' does not provide a sufficiently specific administered-oligo offtarget endpoint for EV71 siRNA.,2026-06-07T02:20:35+00:00
30605,offtarget_evidence,324,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 18066915; no source passage or abstract wording gives a dependable offtarget call for GFP siRNA.,2026-06-07T02:20:35+00:00
30606,offtarget_evidence,325,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 16843436; TAK1 siRNA remains unsupported for transcriptome-level off-target effect after abstract-level review of 'Small interfering RNAs generated by recombinant dicer induce inflammatory gene expression inde?'.,2026-06-07T02:20:35+00:00
30607,offtarget_evidence,326,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 16290277; no source passage or abstract wording gives a dependable offtarget call for siRNA-M184V.,2026-06-07T02:20:35+00:00
30608,offtarget_evidence,327,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 16870272; no source passage or abstract wording gives a dependable offtarget call for WNV siRNA.,2026-06-07T02:20:35+00:00
30609,offtarget_evidence,328,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 16201907; 'Biomembrane-permeable and Ribonuclease-resistant siRNA with enhanced activity.' does not provide a sufficiently specific administered-oligo offtarget endpoint for DNP-siRNA.,2026-06-07T02:20:35+00:00
30610,offtarget_evidence,329,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 16083932; available abstract is not enough to curate off-target evidence for EV71 siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30611,offtarget_evidence,330,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 15707982; no source passage or abstract wording gives a dependable offtarget call for GFP siRNA.,2026-06-07T02:20:35+00:00
30612,offtarget_evidence,331,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for seed-mediated off-target effect in F7-1 siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30613,offtarget_evidence,332,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 18267968; DNA-modified siRNA remains unsupported for seed-mediated off-target effect after abstract-level review of 'Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a?'.,2026-06-07T02:20:35+00:00
30614,offtarget_evidence,333,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In this study, we used three different splice-switching AONs targeting three different human transcripts to study their transcriptome-wide, hybridization-dependent off-target effects with short read RNAseq.",2026-06-07T02:20:35+00:00
30615,offtarget_evidence,334,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The greatest impact of SNA modification was observed when included at position g7 in si-50, with a relative off-target IC50 increase of ~260-fold over the parent si-47.",2026-06-07T02:20:35+00:00
30616,offtarget_evidence,335,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33664996; The paper intentionally designs anticancer siRNAs to exploit tumor-suppressive miRNA-like seed activity and reports efficacy; this is not observed unintended off-target safety evidence under the v2 contract.,2026-06-07T02:20:35+00:00
30617,offtarget_evidence,336,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29718312; available abstract is not enough to curate seed-mediated off-target effect for sli-siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30618,offtarget_evidence,337,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for seed-mediated off-target effect in UNA-T siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30619,offtarget_evidence,338,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for hybridization/mismatch off-target effect in siCD46 siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30620,offtarget_evidence,339,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for seed-mediated off-target effect in BTK siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30621,offtarget_evidence,340,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hybridization/mismatch off-target effect in GR18-3 ASO; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30622,offtarget_evidence,341,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41541269; Passage reports GalNAc-siRNA liver targeting, pharmacokinetics, liver-to-kidney ratios, and PCSK9 silencing; off-target effects are only a delivery-specificity rationale, not observed unintended off-target evidence.",2026-06-07T02:20:35+00:00
30623,offtarget_evidence,342,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26433227 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for ss-siRNA.,2026-06-07T02:20:35+00:00
30624,offtarget_evidence,343,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for hybridization/mismatch off-target effect in SOD-1; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30625,offtarget_evidence,344,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We found that the ESC+ version of ALN-HBV, named ALN-HBV02, with a single GNA substitution at position 6 of the guide strand, and without any further changes in sequence or chemistry, minimizes off-target dysregulation without compromising on-target activity.",2026-06-07T02:20:35+00:00
30626,offtarget_evidence,345,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Consistent with these data, global transcriptome profiling by RNAseq shows RISC loading-dependent downregulation of RNAs enriched for a seed match to the antisense but not the sense strand of GalNAc-siRNAs.",2026-06-07T02:20:35+00:00
30627,offtarget_evidence,346,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,We demonstrate in vitro mRNA and protein knockdown of off-targets with a wide range of mismatch (MM) and gap patterns.,2026-06-07T02:20:35+00:00
30628,offtarget_evidence,347,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24440078 abstract/title reviewed; no clear in-scope seed-mediated off-target effect endpoint is grounded for SCR ASO.,2026-06-07T02:20:35+00:00
30629,offtarget_evidence,348,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for hybridization/mismatch off-target effect in siRNA-604; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30630,offtarget_evidence,349,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41634015; Passage reports intradermal siRNA skin retention, systemic exposure, hematology, and safety parameters; it does not present observed hybridization-, seed-, or transcriptome-level unintended off-target evidence.",2026-06-07T02:20:35+00:00
30631,offtarget_evidence,350,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41898774; Passage designs and tests IL-1beta siRNAs for delivery and on-target knockdown in THP-1 cells; no observed unintended seed-mediated off-target evidence is provided.,2026-06-07T02:20:35+00:00
30632,offtarget_evidence,351,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The effects on off-target genes were validated by microarray and RT-qPCR analyses.,2026-06-07T02:20:35+00:00
30633,offtarget_evidence,352,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39380712; Passage uses Rab18 siRNA and CRISPR-derived models to study regulation of siRNA-mediated silencing; RNA-seq changes are Rab18 biology/trigger-selection context, not therapeutic oligo off-target safety evidence.",2026-06-07T02:20:35+00:00
30634,offtarget_evidence,353,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38979291; Passage describes therapeutic SOD1 siRNA efficacy and tolerated mismatch to the intended NHP SOD1 target; this is on-target cross-reactivity, not unintended off-target evidence.",2026-06-07T02:20:35+00:00
30635,offtarget_evidence,354,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38549376; Passage reports RNAi-mediated silencing of STAT3/PD-L1 and anti-tumor effects; the captured evidence is on-target efficacy, not observed unintended off-target effects.",2026-06-07T02:20:35+00:00
30636,offtarget_evidence,355,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"by performing RNA sequencing (RNA-seq) for cells after ASO treatment, we assessed both on- and off-target effects of the ASOs on a transcriptome-wide level.",2026-06-07T02:20:35+00:00
30637,offtarget_evidence,356,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37315786; Passage concerns RILP-directed shRNAs and an off-target phenotype in neurons; shRNA is explicitly excluded by the v2 contract.,2026-06-07T02:20:35+00:00
30638,offtarget_evidence,357,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36945482; Passage concerns RILP shRNA off-target phenotype analysis; shRNA is explicitly excluded by the v2 contract.,2026-06-07T02:20:35+00:00
30639,offtarget_evidence,358,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37554515; Passage describes an unbiased seed-based RNAi screen and prostate cancer growth inhibition; the small RNAs are screening tools/intentional seed biology, not therapeutic oligo unintended off-target evidence.",2026-06-07T02:20:35+00:00
30640,offtarget_evidence,359,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37467023; available abstract is not enough to curate seed-mediated off-target effect for siVwf5 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30641,offtarget_evidence,360,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35356684; Passage evaluates VEGFA-targeting miR-agshRNAs for retinal gene therapy; AAV/viral gene therapy and shRNA/agshRNA modalities are excluded by the v2 contract.,2026-06-07T02:20:35+00:00
30642,offtarget_evidence,361,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36445136; the abstained record was checked at abstract level, but transcriptome-level off-target effect is still not directly recoverable for siCtle1.",2026-06-07T02:20:35+00:00
30643,offtarget_evidence,362,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33321203; 70 siRNA remains unsupported for seed-mediated off-target effect after abstract-level review of 'A computational approach to design potential siRNA molecules as a prospective tool for silenci?'.,2026-06-07T02:20:35+00:00
30644,offtarget_evidence,363,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33020600; no source passage or abstract wording gives a dependable offtarget call for siSdf1.,2026-06-07T02:20:35+00:00
30645,offtarget_evidence,364,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"When the MOE on the guide strand was combined with OMe at position 14 on the passenger strand, the off-target silencing was almost completely eliminated (Figure 8B).",2026-06-07T02:20:35+00:00
30646,offtarget_evidence,365,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28108657; available abstract is not enough to curate seed-mediated off-target effect for RIsearch2 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30647,offtarget_evidence,366,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29063830; 'Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-targe?' does not provide a sufficiently specific administered-oligo offtarget endpoint for shR6.,2026-06-07T02:20:35+00:00
30648,offtarget_evidence,367,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26197079 abstract/title reviewed; no clear in-scope seed-mediated off-target effect endpoint is grounded for CDCA7L shRNA.,2026-06-07T02:20:35+00:00
30649,offtarget_evidence,368,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26057633; no source passage or abstract wording gives a dependable offtarget call for 27-32.,2026-06-07T02:20:35+00:00
30650,offtarget_evidence,369,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24517546 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for AF9.,2026-06-07T02:20:35+00:00
30651,offtarget_evidence,370,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for seed-mediated off-target effect in 60 siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30652,offtarget_evidence,371,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24561616 abstract/title reviewed; no clear in-scope seed-mediated off-target effect endpoint is grounded for DNA-modified siRNA.,2026-06-07T02:20:35+00:00
30653,offtarget_evidence,372,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24382894; available abstract is not enough to curate transcriptome-level off-target effect for HoxA1 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30654,offtarget_evidence,373,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24972830 abstract/title reviewed; no clear in-scope seed-mediated off-target effect endpoint is grounded for 353 siRNA.,2026-06-07T02:20:35+00:00
30655,offtarget_evidence,374,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23484018; 'Whole-genome thermodynamic analysis reduces siRNA off-target effects.' does not provide a sufficiently specific administered-oligo offtarget endpoint for IDH1 siRNA.,2026-06-07T02:20:35+00:00
30656,offtarget_evidence,375,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23935115; available abstract is not enough to curate hybridization/mismatch off-target effect for ss-siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30657,offtarget_evidence,376,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23145149 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for siR-04.,2026-06-07T02:20:35+00:00
30658,offtarget_evidence,377,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 22064859; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for si2A-AF555.",2026-06-07T02:20:35+00:00
30659,offtarget_evidence,378,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22827812; available abstract is not enough to curate hybridization/mismatch off-target effect for H1-shRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30660,offtarget_evidence,379,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 22694849; 'In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical?' does not provide a sufficiently specific administered-oligo offtarget endpoint for EIF-5A-siRNA.",2026-06-07T02:20:35+00:00
30661,offtarget_evidence,380,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22174890; shRNA18 remains unsupported for off-target evidence after abstract-level review of 'An off-target nucleostemin RNAi inhibits growth in human glioblastoma-derived cancer stem cell?'.,2026-06-07T02:20:35+00:00
30662,offtarget_evidence,381,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 21443765; 'A cell spot microarray method for production of high density siRNA transfection microarrays.' does not provide a sufficiently specific administered-oligo offtarget endpoint for 000 siRNA.,2026-06-07T02:20:35+00:00
30663,offtarget_evidence,382,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 21401928; 'Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and?' does not provide a sufficiently specific administered-oligo offtarget endpoint for TGFBR2.,2026-06-07T02:20:35+00:00
30664,offtarget_evidence,383,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for seed-mediated off-target effect in siEGFP1; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30665,offtarget_evidence,384,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for seed-mediated off-target effect in Ago2; Ago1; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30666,offtarget_evidence,385,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 19061642; no source passage or abstract wording gives a dependable offtarget call for MBD6 siRNA.,2026-06-07T02:20:35+00:00
30667,offtarget_evidence,386,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for seed-mediated off-target effect in TNFR1; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
30668,offtarget_evidence,387,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 16410612; available abstract is not enough to curate off-target evidence for siGL3 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30669,offtarget_evidence,388,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 19771225 abstract/title reviewed; no clear in-scope seed-mediated off-target effect endpoint is grounded for 14-8 siRNA.,2026-06-07T02:20:35+00:00
30670,offtarget_evidence,389,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42112101; ClinASO uses off-target prediction/filtering as a design criterion and validates on-target ASO knockdown; the captured passage does not provide primary observed off-target effect evidence.,2026-06-07T02:20:35+00:00
30671,offtarget_evidence,390,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,This means that there is no clear correlation between the changes in the off-target effects and the hepatotoxicity observed with the introduction of nucleobase modification.,2026-06-07T02:20:35+00:00
30672,offtarget_evidence,391,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->C: PMID 36511872; weak/generic or abstract-limited support for hybridization/mismatch off-target effect.,2026-06-07T02:20:35+00:00
30673,offtarget_evidence,392,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We observed highly selective transcript knockdown in mice treated with non-hepatotoxic LNA ASOs, while the levels of many unintended transcripts were reduced in mice treated with hepatotoxic LNA ASOs.",2026-06-07T02:20:35+00:00
30674,offtarget_evidence,393,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40034209; Reject under v2: passage is a commentary/safety discussion of renal-targeted SNA2-ASO chemistry and says transcriptome-wide off-target analyses are still needed; no primary measured unintended off-target result.,2026-06-07T02:20:35+00:00
30675,offtarget_evidence,394,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No notable adverse drug binding of TMEM16a ASO was observed,2026-06-07T02:20:35+00:00
30676,offtarget_evidence,395,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40758869; 'Harnessing BET-Bromodomain Assisted Nuclear Import for Targeted Subcellular Localization and E?' does not provide a sufficiently specific administered-oligo offtarget endpoint for JQ1-ASO.,2026-06-07T02:20:35+00:00
30677,offtarget_evidence,396,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40529507; available abstract is not enough to curate transcriptome-level off-target effect for SNORA13 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30678,offtarget_evidence,397,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40473123; Reject under v2: source reports on-target SARM1 ASO knockdown and rescue of vacor-induced neuronal toxicity, not observed unintended oligo off-target evidence.",2026-06-07T02:20:35+00:00
30679,offtarget_evidence,398,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39897576; available abstract is not enough to curate hybridization/mismatch off-target effect for GNAO1-neurodevelopmental as a verified offtarget record.,2026-06-07T02:20:35+00:00
30680,offtarget_evidence,399,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39027419; no source passage or abstract wording gives a dependable offtarget call for SSR-5.,2026-06-07T02:20:35+00:00
30681,offtarget_evidence,400,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38654375; APOE-1 ASO remains unsupported for transcriptome-level off-target effect after abstract-level review of 'Regulation of human microglial gene expression and function via RNAase-H active antisense olig?'.,2026-06-07T02:20:35+00:00
30682,offtarget_evidence,401,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39379106; Reject under v2: site-blocking ASOs are designed to modulate MECP2 3-prime UTR miRNA repression; severe phenotypes are explicitly unknown as on- or off-target and no measured off-target assay supports the claim.,2026-06-07T02:20:35+00:00
30683,offtarget_evidence,402,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39303667; 'Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised?' does not provide a sufficiently specific administered-oligo offtarget endpoint for L858R ASO.,2026-06-07T02:20:35+00:00
30684,offtarget_evidence,403,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38511173; 'STAT6-targeting antisense oligonucleotides against solitary fibrous tumor.' does not provide a sufficiently specific administered-oligo offtarget endpoint for STAT6-targeting.,2026-06-07T02:20:35+00:00
30685,offtarget_evidence,404,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37588686; Reject under v2: cyclic ASO passage mainly supports conditional target knockdown and expected lower off-target binding; the off-target claim is design/expectation rather than a primary observed unintended off-target result.,2026-06-07T02:20:35+00:00
30686,offtarget_evidence,405,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36700864; no source passage or abstract wording gives a dependable offtarget call for STAT6.,2026-06-07T02:20:35+00:00
30687,offtarget_evidence,406,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36516128 abstract/title reviewed; no clear in-scope transcriptome-level off-target effect endpoint is grounded for nusinersen.,2026-06-07T02:20:35+00:00
30688,offtarget_evidence,407,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35858356; available abstract is not enough to curate hybridization/mismatch off-target effect for PS ASO as a verified offtarget record.,2026-06-07T02:20:35+00:00
30689,offtarget_evidence,408,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34521352; available abstract is not enough to curate transcriptome-level off-target effect for T0 ASO as a verified offtarget record.,2026-06-07T02:20:35+00:00
30690,offtarget_evidence,409,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33203730; available abstract is not enough to curate hybridization/mismatch off-target effect for STAT3 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30691,offtarget_evidence,410,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32178467; Reject under v2: TGFBR2-A candidate selection used in-silico specificity and mismatch criteria plus efficacy/toxicity screening, but no primary observed unintended off-target effect.",2026-06-07T02:20:35+00:00
30692,offtarget_evidence,411,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"based on analysis of the microarray data, none of the potential off-target transcripts were reduced by >50%",2026-06-07T02:20:35+00:00
30693,offtarget_evidence,412,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28080221; available abstract is not enough to curate hybridization/mismatch off-target effect for PS ASO as a verified offtarget record.,2026-06-07T02:20:35+00:00
30694,offtarget_evidence,413,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 27285612; 45-47 remains unsupported for off-target evidence after abstract-level review of 'Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular?'.,2026-06-07T02:20:35+00:00
30695,offtarget_evidence,414,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The P53 and Nrf2/ARE reporters were substantially induced by compound 3 but not by 1a or 1b, suggesting these pathways may be associated with motif-related hepatotoxicity.",2026-06-07T02:20:35+00:00
30696,offtarget_evidence,415,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"expression levels of HHLA2, GRHL2, and DPP10 were unchanged compared with vehicle-treated controls",2026-06-07T02:20:35+00:00
30697,offtarget_evidence,416,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,We used RNA sequencing (RNA-seq) to perform transcriptome-wide analysis of gene expression patterns in human iPSC-derived neurons before and after gymnotic treatment and found none of these potential targets to be significantly perturbed by KT777,2026-06-07T02:20:35+00:00
30698,offtarget_evidence,417,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,oligonucleotide with a mismatched sequence,2026-06-07T02:20:35+00:00
30699,offtarget_evidence,418,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41630988; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for PS-ASO.",2026-06-07T02:20:35+00:00
30700,offtarget_evidence,419,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41383013; available abstract is not enough to curate off-target evidence for BLOC1S1 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30701,offtarget_evidence,420,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41012491; Reject under v2: source is PBPK/PK-PD modeling of GalNAc-siRNA tissue disposition and off-target organ exposure; contract explicitly rejects PK/biodistribution-only evidence.,2026-06-07T02:20:35+00:00
30702,offtarget_evidence,421,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40898620; DFNA2 remains unsupported for hybridization/mismatch off-target effect after abstract-level review of 'Antisense oligonucleotide therapy mitigates autosomal dominant progressive hearing loss in a m?'.,2026-06-07T02:20:35+00:00
30703,offtarget_evidence,422,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40473796; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for NRAS ASO.",2026-06-07T02:20:35+00:00
30704,offtarget_evidence,423,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39955311 abstract/title reviewed; no clear in-scope transcriptome-level off-target effect endpoint is grounded for ASO-1570.,2026-06-07T02:20:35+00:00
30705,offtarget_evidence,424,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39292801; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for 1504-818.",2026-06-07T02:20:35+00:00
30706,offtarget_evidence,425,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39277796; the abstained record was checked at abstract level, but transcriptome-level off-target effect is still not directly recoverable for MECP2.",2026-06-07T02:20:35+00:00
30707,offtarget_evidence,426,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39155863; no source passage or abstract wording gives a dependable offtarget call for CALM2 ASO.,2026-06-07T02:20:35+00:00
30708,offtarget_evidence,427,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38973655; Reject under v2: SORT siRNA LNP passage reports organ targeting, reporter knockdown, biodistribution, and toxicology, not unintended molecular off-target evidence.",2026-06-07T02:20:35+00:00
30709,offtarget_evidence,428,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38189760; Reject under v2: RNA-seq describes downstream transcriptome after intended IGFBP3 knockdown and myogenesis biology, not unintended off-target analysis.",2026-06-07T02:20:35+00:00
30710,offtarget_evidence,429,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36910710; no source passage or abstract wording gives a dependable offtarget call for ABCA4.,2026-06-07T02:20:35+00:00
30711,offtarget_evidence,430,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36669889; available abstract is not enough to curate hybridization/mismatch off-target effect for nusinersen as a verified offtarget record.,2026-06-07T02:20:35+00:00
30712,offtarget_evidence,431,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36824749; no source passage or abstract wording gives a dependable offtarget call for PRNP ASO.,2026-06-07T02:20:35+00:00
30713,offtarget_evidence,432,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37552050; Reject under v2: ARTi/shRNAmir is an shRNA loss-of-function tool and target-validation system; shRNA and lab-tool RNAi are explicitly out of scope.,2026-06-07T02:20:35+00:00
30714,offtarget_evidence,433,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37235843; available abstract is not enough to curate hybridization/mismatch off-target effect for MALAT1 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30715,offtarget_evidence,434,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37043556; no source passage or abstract wording gives a dependable offtarget call for 11-15.,2026-06-07T02:20:35+00:00
30716,offtarget_evidence,435,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37193356; Reject under v2: review article on marketed ASO nephrotoxicity and safety warnings, not a primary observed off-target experiment.",2026-06-07T02:20:35+00:00
30717,offtarget_evidence,436,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Our RNA-seq data revealed that MAPT is the only differentially regulated gene,2026-06-07T02:20:35+00:00
30718,offtarget_evidence,437,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35037525; Reject under v2: siRNA nanodroplet passage supports targeted delivery, cytotoxicity, and anti-tumor knockdown, with no measured unintended off-target result.",2026-06-07T02:20:35+00:00
30719,offtarget_evidence,438,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35327991; GAAA-3 remains unsupported for hybridization/mismatch off-target effect after abstract-level review of 'The Effect of Dicer Knockout on RNA Interference Using Various Dicer Substrate Small Interferi?'.,2026-06-07T02:20:35+00:00
30720,offtarget_evidence,439,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34492058; WT siRNA remains unsupported for hybridization/mismatch off-target effect after abstract-level review of 'Beyond identity: Understanding the contribution of the 5' nucleotide of the antisense strand t?'.,2026-06-07T02:20:35+00:00
30721,offtarget_evidence,440,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33978760; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for BCL-2.",2026-06-07T02:20:35+00:00
30722,offtarget_evidence,441,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,strongly suggesting an off-target effect of the T39 ASO,2026-06-07T02:20:35+00:00
30723,offtarget_evidence,442,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 31083481; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for NR2E3-Associated.",2026-06-07T02:20:35+00:00
30724,offtarget_evidence,443,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 29858079; Reject under v2: HBV SSO passage reports pan-genotypic viral target conservation, antiviral efficacy, and immunotoxicity/hepatotoxicity screens, not unintended off-target evidence.",2026-06-07T02:20:35+00:00
30725,offtarget_evidence,444,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23217017; no source passage or abstract wording gives a dependable offtarget call for CTGTAGGCACCATCAAT-3.,2026-06-07T02:20:35+00:00
30726,offtarget_evidence,445,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 22615794; Reject under v2: single-strand oligos are used for EGFP reporter genome targeting in human cells, a lab genome-engineering tool rather than therapeutic oligo safety evidence.",2026-06-07T02:20:35+00:00
30727,offtarget_evidence,446,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 21744502; 'Current progress of siRNA/shRNA therapeutics in clinical trials.' does not provide a sufficiently specific administered-oligo offtarget endpoint for VEGF siRNA.,2026-06-07T02:20:35+00:00
30728,offtarget_evidence,447,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 19430205; 'A short antisense oligonucleotide masking a unique intronic motif prevents skipping of a criti?' does not provide a sufficiently specific administered-oligo offtarget endpoint for 42-49.,2026-06-07T02:20:35+00:00
30729,offtarget_evidence,448,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41810141; Reject under v2: commentary on GalNAc delivery scaffold, PCSK9/AGT siRNA toxicology, and liver targeting; no observed unintended off-target assay.",2026-06-07T02:20:35+00:00
30730,offtarget_evidence,449,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42033217 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for HTT siRNA.,2026-06-07T02:20:35+00:00
30731,offtarget_evidence,450,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41867745; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for HTT siRNA.",2026-06-07T02:20:35+00:00
30732,offtarget_evidence,451,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,no enrichment of predicted off-target transcripts among genes with significantly downregulated expressions was observed,2026-06-07T02:20:35+00:00
30733,offtarget_evidence,452,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41948127; reject: AAV-delivered miRNA/gene therapy is explicitly excluded; passage concerns on-target specificity, toxicity, and biodistribution, not observed oligo off-target evidence",2026-06-07T02:20:35+00:00
30734,offtarget_evidence,453,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42139331; reject: EV siPD-L1 passage reports lung targeting, biodistribution, protein corona, and tumor efficacy; no observed unintended molecular off-target effect",2026-06-07T02:20:35+00:00
30735,offtarget_evidence,454,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41647289; reject: FGFR2 siRNA passage reports delivery and intended FGFR2/osteogenic modulation; off-target language is generic/prior rationale, not a primary observed off-target result",2026-06-07T02:20:35+00:00
30736,offtarget_evidence,455,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41612694; reject: IRS2 siRNAs were computationally filtered to minimize seed/complementarity risks; no observed unintended off-target knockdown result is reported in the loaded passage,2026-06-07T02:20:35+00:00
30737,offtarget_evidence,456,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In the first reporter assay using the AR28Q or AR54Q vectors, REP suppressed both the AR28Q and AR54Q proteins, whereas P9, S9, P9S9, P9S10, and P9S910 selectivity suppressed the AR54Q protein (Figure S1C).",2026-06-07T02:20:35+00:00
30738,offtarget_evidence,457,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 40770503; previous accept was too weak/generic for off-target evidence in LNP-siRNA. Basis checked: Therapeutic siVEGF-A/siBcl-2 delivery study includes a primary measured negative off-target downregulation control; evidence is narrow, so grade C.",2026-06-07T02:20:35+00:00
30739,offtarget_evidence,458,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42009652; PKM-ASO remains unsupported for off-target evidence after abstract-level review of 'ASO-based PKM splice-switching therapy increases anti-CTLA-4 antibody efficacy in pancreatic d?'.,2026-06-07T02:20:35+00:00
30740,offtarget_evidence,459,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41872964; reject: mosquito/insect RNAi functional knockdown is explicitly excluded and is not therapeutic oligo off-target evidence,2026-06-07T02:20:35+00:00
30741,offtarget_evidence,460,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41770218; the abstained record was checked at abstract level, but seed-mediated off-target effect is still not directly recoverable for shRNA-GNEM743T.",2026-06-07T02:20:35+00:00
30742,offtarget_evidence,461,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41632828; available abstract is not enough to curate transcriptome-level off-target effect for PSMD1 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30743,offtarget_evidence,462,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"However, two siRNAs, si098-DV29P and si086-DV26P, exerted relatively strong inhibition on their potential off-target genes (Figures S10B and S10E), suggesting that measures should be taken to prevent and control the off-target risk.",2026-06-07T02:20:35+00:00
30744,offtarget_evidence,463,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"bsYW-61 reduced luciferase activity in the guide strand seed reporter, confirming seed-mediated off-target effects (Figure 6I).",2026-06-07T02:20:35+00:00
30745,offtarget_evidence,464,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,transcriptome-wide off-target editing events as compared to plasmid-based expression of TadA8.20-HaloTag.,2026-06-07T02:20:35+00:00
30746,offtarget_evidence,465,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39778469 abstract/title reviewed; no clear in-scope transcriptome-level off-target effect endpoint is grounded for TNF ASO.,2026-06-07T02:20:35+00:00
30747,offtarget_evidence,466,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40893381; reject: ECM-EGFR siRNA passage reports cardiac delivery, fibrosis repair, and EGFR pathway efficacy; no observed unintended off-target molecular effect",2026-06-07T02:20:35+00:00
30748,offtarget_evidence,467,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40520362; A4GALT-siRNA remains unsupported for transcriptome-level off-target effect after abstract-level review of 'A4GALT-targeting siRNA lipid nanoparticles ameliorate Fabry disease phenotype: Greater efficac?'.,2026-06-07T02:20:35+00:00
30749,offtarget_evidence,468,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40171444; reject: modified siRNA potency/modeling study focuses on thermodynamics, molecular modeling, and activity prediction; no administered therapeutic off-target result",2026-06-07T02:20:35+00:00
30750,offtarget_evidence,469,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41402667; reject: aptamer-siRNA chimera evidence concerns PD-L1 binding specificity, peripheral sparing, biodistribution, and antitumor efficacy; no observed unintended siRNA off-target effect",2026-06-07T02:20:35+00:00
30751,offtarget_evidence,470,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41045966; reject: review-style nanocarrier passage about brain siRNA delivery, not primary observed off-target evidence for an administered therapeutic oligo",2026-06-07T02:20:35+00:00
30752,offtarget_evidence,471,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40917515; reject: SKOV3 siRNAs are used as cancer-on-chip knockdown tools for invasion/efficacy; no observed unintended off-target evidence,2026-06-07T02:20:35+00:00
30753,offtarget_evidence,472,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40873646; reject: BACE1 siRNA transcriptome analysis compares treated AD mice with disease controls and supports therapeutic mechanism/biocompatibility, not unintended off-target effects",2026-06-07T02:20:35+00:00
30754,offtarget_evidence,473,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Unexpectedly, the 2nd generation Cond-siRNA also appeared to decrease NFATc1 levels in the PBS group (independent of its effect on PPP3CA), suggesting an off-target effect or a cellular stress response to this chemical entity.",2026-06-07T02:20:35+00:00
30755,offtarget_evidence,474,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40761479; reject: NSUN4 siRNA passage concerns SLE mechanism, CD8 exhaustion, and therapeutic efficacy; scRNA/m5C data are disease biology, not oligo off-target evidence",2026-06-07T02:20:35+00:00
30756,offtarget_evidence,475,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40715133; sFRP2 remains unsupported for transcriptome-level off-target effect after abstract-level review of 'Identifying fibroblast-derived sFRP2 as a therapeutic target and engineering siRNA therapy for?'.,2026-06-07T02:20:35+00:00
30757,offtarget_evidence,476,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40704506; no source passage or abstract wording gives a dependable offtarget call for siSmyd3.,2026-06-07T02:20:35+00:00
30758,offtarget_evidence,477,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40673060; reject: DUX4 siRNA RNA-seq supports target specificity and toxicity/safety assessment; no passage-grounded unintended off-target effect is reported,2026-06-07T02:20:35+00:00
30759,offtarget_evidence,478,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40415115; reject: endogenous CD39 antisense/lncRNA immune-metabolism biology and knockdown experiments are excluded; no therapeutic off-target evidence,2026-06-07T02:20:35+00:00
30760,offtarget_evidence,479,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39657790; 'High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with t?' does not provide a sufficiently specific administered-oligo offtarget endpoint for siRNA2.,2026-06-07T02:20:35+00:00
30761,offtarget_evidence,480,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39632755; reject: MYC asiRNA study discusses off-target mitigation and uses scramble/mismatch controls, but loaded passage reports design and antitumor knockdown efficacy rather than observed off-target activity",2026-06-07T02:20:35+00:00
30762,offtarget_evidence,481,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41341746 abstract/title reviewed; no clear in-scope transcriptome-level off-target effect endpoint is grounded for CD81 ASO.,2026-06-07T02:20:35+00:00
30763,offtarget_evidence,482,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41226635; reject: CXCR4-targeted anti-VEGFA siRNA passage reports polyplex delivery, targeting specificity, and lesion efficacy; no observed unintended off-target molecular effect",2026-06-07T02:20:35+00:00
30764,offtarget_evidence,483,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 40928446; pmc_full_text evidence was direct but less than full primary-detail confidence for seed-mediated off-target effect.,2026-06-07T02:20:35+00:00
30765,offtarget_evidence,484,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40762837; reject: MYC/KRAS chimera RNA-seq is used to conclude intended target specificity; off-target transcriptional profiling is stated as future work, not an observed result",2026-06-07T02:20:35+00:00
30766,offtarget_evidence,485,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40060931; reject: VCA-894A off-target binding was assessed by in silico BLAST/predicted transcriptome matches; no observed administered/measured off-target result,2026-06-07T02:20:35+00:00
30767,offtarget_evidence,486,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40290881; reject: passage contains only generic siRNA off-target-risk language and delivery/efficacy results; no primary measured unintended KRAS siRNA off-target effect,2026-06-07T02:20:35+00:00
30768,offtarget_evidence,487,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40141224; the abstained record was checked at abstract level, but off-target evidence is still not directly recoverable for 0001 ASO.",2026-06-07T02:20:35+00:00
30769,offtarget_evidence,488,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39752485; reject: scRNA-seq/transcriptome data support macrophage targeting and intended OA-NO2/siSTAT1 phenotype modulation, not unintended siSTAT1 off-target evidence",2026-06-07T02:20:35+00:00
30770,offtarget_evidence,489,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39558155; available abstract is not enough to curate hybridization/mismatch off-target effect for PA5-78644 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30771,offtarget_evidence,490,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39171140; reject: RNA-seq/scRNA-seq results describe intended CpG-STAT3d leukemic-cell differentiation and immune reprogramming; no observed unintended oligo off-target result,2026-06-07T02:20:35+00:00
30772,offtarget_evidence,491,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38664825; reject: siRNAs are used as mechanistic knockdown tools for drug-resistant breast cancer pathways; transcriptome/microarray data identify targets and efficacy mechanisms, not oligo off-target effects",2026-06-07T02:20:35+00:00
30773,offtarget_evidence,492,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38304729; reject: JAK1 siRNAs were filtered for seed/complementarity and cross-species targetability; no experimental unintended off-target silencing result is reported,2026-06-07T02:20:35+00:00
30774,offtarget_evidence,493,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The in silico predictions were confirmed experimentally in CD3/CD28 bead-activated human pan T cells, where no off-target silencing GRAMD4 mRNA was observed, such that an IC50 for PH-762 toward GRAMD4 mRNA could not be determined",2026-06-07T02:20:35+00:00
30775,offtarget_evidence,494,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39902039; reject: transcriptome sequencing identified IIRI biomarkers and CCL7 therapeutic rationale; off-target language is future/generic delivery discussion without measured unintended siCCL7 off-target evidence,2026-06-07T02:20:35+00:00
30776,offtarget_evidence,495,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39225143; reject: passage reports MSC/NP biodistribution, organ accumulation, and systemic safety; no observed molecular HIF-1? siRNA off-target effect",2026-06-07T02:20:35+00:00
30777,offtarget_evidence,496,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38348876; 'A combinatorial approach for achieving CNS-selective RNAi.' does not provide a sufficiently specific administered-oligo offtarget endpoint for APOE ASO.,2026-06-07T02:20:35+00:00
30778,offtarget_evidence,497,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38727303; no source passage or abstract wording gives a dependable offtarget call for Il6.,2026-06-07T02:20:35+00:00
30779,offtarget_evidence,498,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37788110; 'A splice-switching oligonucleotide treatment ameliorates glycogen storage disease type 1a in m?' does not provide a sufficiently specific administered-oligo offtarget endpoint for PS-ASO.,2026-06-07T02:20:35+00:00
30780,offtarget_evidence,499,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37438524; reject: ASO off-target profiles are in silico genomic predictions compared with nusinersen/milasen plus toxicity testing; no observed off-target hybridization result,2026-06-07T02:20:35+00:00
30781,offtarget_evidence,500,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36727438; reject: BC-893 is a small-molecule endolysosomal trafficking modulator and off-target wording concerns small-molecule inhibitor specificity; not observed therapeutic oligo off-target evidence,2026-06-07T02:20:35+00:00
30782,offtarget_evidence,501,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37925520; reject: JAK-family and reporter assays measure intended JAK1 selectivity/signaling efficacy; off-target-risk discussion is design rationale, not unintended siRNA off-target observation",2026-06-07T02:20:35+00:00
30783,offtarget_evidence,502,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37016578; reject: RBCEV passage reports siRNA delivery, cachexia efficacy, toxicity and inflammation safety; no primary observed unintended off-target gene effect",2026-06-07T02:20:35+00:00
30784,offtarget_evidence,503,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36881759; reject: review article discusses oligonucleotide chemistry and general off-target risks, not a primary administered/measured off-target result for a specific therapeutic oligo",2026-06-07T02:20:35+00:00
30785,offtarget_evidence,504,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38015828; reject: transcriptomics describe pathways downstream of intended Atp1a2 knockdown in ALS models; abstract states no off-target/systemic toxicity but gives no grounded measured unintended off-target effect,2026-06-07T02:20:35+00:00
30786,offtarget_evidence,505,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36789273; reject: C5-siRNA sequence-walk and screening demonstrate intended target specificity and efficacy; no unintended transcript or seed-mediated off-target result,2026-06-07T02:20:35+00:00
30787,offtarget_evidence,506,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"It was found that modified CT102s could decrease IGF1R mRNA expression levels in both the nucleus and cytoplasm (Figure 6F) and had a significant effect on the expression of GAS2 (GenBank: NM_001143830), POLA2 (GenBank: NM_002689), LGALS2 (GenBank: NM_006498), and IGFBP1 (GenBank: NM_000596), which have functional roles in the occurrence and development of tumors, possibly by imperfect base pairing",2026-06-07T02:20:35+00:00
30788,offtarget_evidence,507,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37031257; reject: study is an AAV-delivered transgene rheostat using siRNA/shRNA/REVERSIR; AAV and shRNA/vector transgene-control systems are explicitly excluded despite off-target reporter data,2026-06-07T02:20:35+00:00
30789,offtarget_evidence,508,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37272117; A01406-33 remains unsupported for seed-mediated off-target effect after abstract-level review of 'Biochemistry-informed design selects potent siRNAs against SARS-CoV-2.'.,2026-06-07T02:20:35+00:00
30790,offtarget_evidence,509,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37353152; available abstract is not enough to curate hybridization/mismatch off-target effect for siT10 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30791,offtarget_evidence,510,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Except for the pseudogene LPAL2, none of the other identified potential off targets, nor PLG, showed any concentration-dependent reduction in mRNA expression up to SLN360 concentrations of 1000 nM, over 300-fold the IC50 for SLN360 in primary human hepatocytes",2026-06-07T02:20:35+00:00
30792,offtarget_evidence,511,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35922434 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for LNA ASO.,2026-06-07T02:20:35+00:00
30793,offtarget_evidence,512,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36180523; no source passage or abstract wording gives a dependable offtarget call for siCpWnt3.,2026-06-07T02:20:35+00:00
30794,offtarget_evidence,513,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35409410; the abstained record was checked at abstract level, but seed-mediated off-target effect is still not directly recoverable for KCNQ1; QT1.",2026-06-07T02:20:35+00:00
30795,offtarget_evidence,514,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34286840; no source passage or abstract wording gives a dependable offtarget call for siHJ1D8.,2026-06-07T02:20:35+00:00
30796,offtarget_evidence,515,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34683974; reject: LINC01257 siRNA-LNP results address lncRNA-targeted AML efficacy and healthy PBMC viability/toxicity, not measured unintended off-target transcript silencing",2026-06-07T02:20:35+00:00
30797,offtarget_evidence,516,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33738134; reject: CAG-siRNA reporter and mismatch data measure mutant-vs-normal CAG/AR allele selectivity and efficacy; no clearly observed unintended non-target transcript off-target effect,2026-06-07T02:20:35+00:00
30798,offtarget_evidence,517,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34959463; reject: EGFR siRNA carrier passage concerns tumor-targeted delivery, serum stability, and low toxicity; off-target wording is generic delivery-vector background",2026-06-07T02:20:35+00:00
30799,offtarget_evidence,518,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33519276; reject: MERS-CoV ORF1ab siRNAs were computationally filtered to avoid human off-target matches; experimental work validates antiviral efficacy/cytotoxicity, not off-target silencing",2026-06-07T02:20:35+00:00
30800,offtarget_evidence,519,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33992805; the abstained record was checked at abstract level, but seed-mediated off-target effect is still not directly recoverable for siUC7.",2026-06-07T02:20:35+00:00
30801,offtarget_evidence,520,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34696460; 'Inhibition of SARS-CoV-2 Replication by a Small Interfering RNA Targeting the Leader Sequence.' does not provide a sufficiently specific administered-oligo offtarget endpoint for siCoV3.,2026-06-07T02:20:35+00:00
30802,offtarget_evidence,521,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32416156; reject: siRNA library screening is used as a discovery/knockdown tool in Barrett/EAC cells; microarray data are disease/low-pH gene-expression context, not therapeutic oligo off-target evidence",2026-06-07T02:20:35+00:00
30803,offtarget_evidence,522,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31705875; 'Allele-Specific Small Interfering RNA Corrects Aberrant Cellular Phenotype in Keratitis-Ichthy?' does not provide a sufficiently specific administered-oligo offtarget endpoint for AS-siRNA.,2026-06-07T02:20:35+00:00
30804,offtarget_evidence,523,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32817447; no source passage or abstract wording gives a dependable offtarget call for ADAR1.,2026-06-07T02:20:35+00:00
30805,offtarget_evidence,524,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32296040; no source passage or abstract wording gives a dependable offtarget call for TPPP siRNA.,2026-06-07T02:20:35+00:00
30806,offtarget_evidence,525,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31855834; available abstract is not enough to curate seed-mediated off-target effect for eIF3m as a verified offtarget record.,2026-06-07T02:20:35+00:00
30807,offtarget_evidence,526,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Thus, there were only two potential genes, APOLD1 (~ 40% down) and ANLN (~ 20% down), that may be down-regulated due to miRNA-like off-target silencing",2026-06-07T02:20:35+00:00
30808,offtarget_evidence,527,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31213643; no source passage or abstract wording gives a dependable offtarget call for 85 siRNA.,2026-06-07T02:20:35+00:00
30809,offtarget_evidence,528,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 30860482; available abstract is not enough to curate seed-mediated off-target effect for SMARCB1 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30810,offtarget_evidence,529,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31100613; available abstract is not enough to curate transcriptome-level off-target effect for Serpinh1 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30811,offtarget_evidence,530,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Using a 2-fold change as a cutoff, 44 differentially expressed genes were identified, but none has complementarity to QR-110 (Table S8)",2026-06-07T02:20:35+00:00
30812,offtarget_evidence,531,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29438442 abstract/title reviewed; no clear in-scope transcriptome-level off-target effect endpoint is grounded for GluN3A.,2026-06-07T02:20:35+00:00
30813,offtarget_evidence,532,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29963629 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for 7C1 siRNA.,2026-06-07T02:20:35+00:00
30814,offtarget_evidence,533,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29334995; 'Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for?' does not provide a sufficiently specific administered-oligo offtarget endpoint for Upf3b.,2026-06-07T02:20:35+00:00
30815,offtarget_evidence,534,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Our data show that liver toxicity of LNA-containing gapmer ASOs is associated with their ability to hybridize to off-target transcripts and downregulate their expression.,2026-06-07T02:20:35+00:00
30816,offtarget_evidence,535,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28423565 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for LNA-siRNA.,2026-06-07T02:20:35+00:00
30817,offtarget_evidence,536,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 27928054; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for shRT5.",2026-06-07T02:20:35+00:00
30818,offtarget_evidence,537,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28860767; available abstract is not enough to curate transcriptome-level off-target effect for VEGF siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30819,offtarget_evidence,538,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28181832; available abstract is not enough to curate transcriptome-level off-target effect for EGFR-siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30820,offtarget_evidence,539,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28797448; no source passage or abstract wording gives a dependable offtarget call for siCIP2A.,2026-06-07T02:20:35+00:00
30821,offtarget_evidence,540,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28535375; 'MORC-1 Integrates Nuclear RNAi and Transgenerational Chromatin Architecture to Promote Germlin?' does not provide a sufficiently specific administered-oligo offtarget endpoint for MORC-1.,2026-06-07T02:20:35+00:00
30822,offtarget_evidence,541,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28352154; available abstract is not enough to curate off-target evidence for HMGB1 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30823,offtarget_evidence,542,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26997282 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for 000 shRNA.,2026-06-07T02:20:35+00:00
30824,offtarget_evidence,543,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 27259398; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for TLR-3.",2026-06-07T02:20:35+00:00
30825,offtarget_evidence,544,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26815386 abstract/title reviewed; no clear in-scope transcriptome-level off-target effect endpoint is grounded for 80 siRNA.,2026-06-07T02:20:35+00:00
30826,offtarget_evidence,545,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 27583545; OVCAR-8 remains unsupported for off-target evidence after abstract-level review of 'Comparison of Modular PEG Incorporation Strategies for Stabilization of Peptide-siRNA Nanocomp?'.,2026-06-07T02:20:35+00:00
30827,offtarget_evidence,546,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26902267; PINK1 siRNA remains unsupported for seed-mediated off-target effect after abstract-level review of 'An interactive web-based application for Comprehensive Analysis of RNAi-screen Data.'.,2026-06-07T02:20:35+00:00
30828,offtarget_evidence,547,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26516083; 'Properties of short double-stranded RNAs carrying randomized base pairs: toward better control?' does not provide a sufficiently specific administered-oligo offtarget endpoint for siRND4.,2026-06-07T02:20:35+00:00
30829,offtarget_evidence,548,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 25550431; available abstract is not enough to curate hybridization/mismatch off-target effect for THIOMAB-siRNA as a verified offtarget record.,2026-06-07T02:20:35+00:00
30830,offtarget_evidence,549,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 25100204; the abstained record was checked at abstract level, but hybridization/mismatch off-target effect is still not directly recoverable for 20-70.",2026-06-07T02:20:35+00:00
30831,offtarget_evidence,550,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24523631; 'RNAi-mediated knockdown of IKK1 in transgenic mice using a transgenic construct containing the?' does not provide a sufficiently specific administered-oligo offtarget endpoint for IKK1.,2026-06-07T02:20:35+00:00
30832,offtarget_evidence,551,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24619206 abstract/title reviewed; no clear in-scope hybridization/mismatch off-target effect endpoint is grounded for siEphA2.,2026-06-07T02:20:35+00:00
30833,offtarget_evidence,552,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 25373910; no source passage or abstract wording gives a dependable offtarget call for HIV-1.,2026-06-07T02:20:35+00:00
30834,offtarget_evidence,553,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24145823; GAPDH siRNA remains unsupported for seed-mediated off-target effect after abstract-level review of 'Rational design of microRNA-siRNA chimeras for multifunctional target suppression.'.,2026-06-07T02:20:35+00:00
30835,offtarget_evidence,554,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23844368; no source passage or abstract wording gives a dependable offtarget call for DARPP-32 siRNA.,2026-06-07T02:20:35+00:00
30836,offtarget_evidence,555,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23061798; no source passage or abstract wording gives a dependable offtarget call for NRF2; KEAP1; CCL11.,2026-06-07T02:20:35+00:00
30837,offtarget_evidence,556,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22100984 abstract/title reviewed; no clear in-scope transcriptome-level off-target effect endpoint is grounded for 2016-27.,2026-06-07T02:20:35+00:00
30838,offtarget_evidence,557,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 23118925; the abstained record was checked at abstract level, but seed-mediated off-target effect is still not directly recoverable for CSNK2A1 siRNA.",2026-06-07T02:20:35+00:00
30839,offtarget_evidence,558,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22939619; 'Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin exp?' does not provide a sufficiently specific administered-oligo offtarget endpoint for ss-siRNA.,2026-06-07T02:20:35+00:00
30840,offtarget_evidence,559,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22309035 abstract/title reviewed; no clear in-scope off-target evidence endpoint is grounded for PEG-2000.,2026-06-07T02:20:35+00:00
30841,offtarget_evidence,560,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23209368; 'Low molecular weight chitosan conjugated with folate for siRNA delivery in vitro: optimization?' does not provide a sufficiently specific administered-oligo offtarget endpoint for SSB siRNA.,2026-06-07T02:20:35+00:00
30842,offtarget_evidence,561,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22934950 abstract/title reviewed; no clear in-scope seed-mediated off-target effect endpoint is grounded for QGP-1.,2026-06-07T02:20:35+00:00
30843,offtarget_evidence,562,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22162773; available abstract is not enough to curate off-target evidence for STAT6 as a verified offtarget record.,2026-06-07T02:20:35+00:00
30844,offtarget_evidence,563,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 21356167; the abstained record was checked at abstract level, but off-target evidence is still not directly recoverable for LFA-1.",2026-06-07T02:20:35+00:00
30845,offtarget_evidence,564,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 21712955; LRRK2 remains unsupported for hybridization/mismatch off-target effect after abstract-level review of 'Efficient allele-specific targeting of LRRK2 R1441 mutations mediated by RNAi.'.,2026-06-07T02:20:35+00:00
30846,offtarget_evidence,565,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 21819628; 'The effects of stem length and core placement on shRNA activity.' does not provide a sufficiently specific administered-oligo offtarget endpoint for 21-5.,2026-06-07T02:20:35+00:00
30847,toxicity_endpoint,1,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Notably, these condensates become enzymatically active and erroneously elicit the DNA damage response in the absence of DNA damage, activating cell cycle checkpoints, disturbing endogenous repair and causing accumulation of toxic DNA lesions.",2026-06-07T02:20:35+00:00
30848,toxicity_endpoint,2,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Safety characterization is based on in vitro, in vivo, and clinical data from literature and an in-house study where ALT levels were measured in an acute tolerability study in male BALB/c mice administered with 150 mg/kg ASO by subcutaneous injection.",2026-06-07T02:20:35+00:00
30849,toxicity_endpoint,3,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 41783787; previous accept was too weak/generic for cytotoxicity/cytotoxicity in GalNAc-siCEBP?. Basis checked: Full-text Results state no cytotoxicity for GalNAc-siCEBP?, but the cytotoxicity data are not shown, so the evidence is weak.",2026-06-07T02:20:35+00:00
30850,toxicity_endpoint,4,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"ASO2 and ASO3 caused a severe reduction in body weight, whereas ASO1 and ASO4 also induced a significant decrease (Figure S3).",2026-06-07T02:20:35+00:00
30851,toxicity_endpoint,5,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Compared to the vehicle and scrambled control groups, BND6482-treated mice showed no significant alterations in serum markers indicative of hepatotoxicity (Fig. 10A).",2026-06-07T02:20:35+00:00
30852,toxicity_endpoint,6,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Collectively, these data demonstrate that L2-siRNA is well tolerated in aged mice, with no evidence of systemic toxicity, neuroinflammation, or organ dysfunction.",2026-06-07T02:20:35+00:00
30853,toxicity_endpoint,7,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In contrast, mice treated with TP-siRC@tHyNPs maintained stable hematological and biochemical indices throughout the 28-day administration period.",2026-06-07T02:20:35+00:00
30854,toxicity_endpoint,8,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,blood urea nitrogen levels without inducing hepatotoxicity,2026-06-07T02:20:35+00:00
30855,toxicity_endpoint,9,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,injection site reactions including pain and erythema,2026-06-07T02:20:35+00:00
30856,toxicity_endpoint,10,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We next evaluated the cytotoxicity of ASO1 and ASO2 as well as the effect of hypoxanthine substitution, Neuro-2a mouse neuroblastoma cells were transfected with ASOs, and LDH release together with cell viability was measured 48 h later.",2026-06-07T02:20:35+00:00
30857,toxicity_endpoint,11,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,exhibited cell viability >95% (Figure 1A),2026-06-07T02:20:35+00:00
30858,toxicity_endpoint,12,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"During development of RGLS4326, unexpected CNS toxicity (characterized by abnormal gait, lateral recumbency, ataxia, and lethargy) and mortality (including unscheduled euthanasia due to moribundity) were observed in a chronic toxicity study in mice (Supplementary Table 1).",2026-06-07T02:20:35+00:00
30859,toxicity_endpoint,13,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,TEAEs caused discontinuation or deaths were observed.,2026-06-07T02:20:35+00:00
30860,toxicity_endpoint,14,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41220634; Reject: the claimed cytotoxicity is cancer-cell-killing/anti-cancer efficacy for PNAT524 conjugates, which the toxicity contract excludes.",2026-06-07T02:20:35+00:00
30861,toxicity_endpoint,15,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,indicating the absence of acute cytotoxicity,2026-06-07T02:20:35+00:00
30862,toxicity_endpoint,16,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Safety and tolerability of study drugs and procedures were evaluated via assessments of adverse events (AEs), including serious AEs (SAEs), physical examination, and laboratory abnormalities, including changes in ALT throughout the study.",2026-06-07T02:20:35+00:00
30863,toxicity_endpoint,17,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Furthermore, blood tests for hepatic function indicators (ALT and AST levels) and renal function indicators (creatinine and BUN levels) revealed no significant systemic toxicity across all groups (Fig. 6B).",2026-06-07T02:20:35+00:00
30864,toxicity_endpoint,18,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No differences in the indicators of liver and kidney function were observed among the control, Cet@ZIF-8@TCM, siFAK@ZIF-8@TCM, and Cet/siFAK@ZIF-8@TCM groups (Fig. 7A).",2026-06-07T02:20:35+00:00
30865,toxicity_endpoint,19,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Detection for serum levels of ALT, AST, BUN, and Cre also indicated no significant differences in liver and kidney functions among the groups (Fig. 8C).",2026-06-07T02:20:35+00:00
30866,toxicity_endpoint,20,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 40673060; weak/generic or abstract-limited support for general safety/transcriptome toxicity.,2026-06-07T02:20:35+00:00
30867,toxicity_endpoint,21,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Histological examination of major organs, including the heart, liver, spleen, lung, and kidneys, revealed no noticeable changes or damage in H&E-stained sections following intravenous injection of each EV sample (Figure 6A).",2026-06-07T02:20:35+00:00
30868,toxicity_endpoint,22,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 40896585; weak/generic or abstract-limited support for immunotoxicity/immune activation.,2026-06-07T02:20:35+00:00
30869,toxicity_endpoint,23,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Moreover, ELISA indicated that GSC and BSCgal treatments did not trigger an elevation of inflammatory markers, such as C-reactive protein, procalcitonin and interleukin-6, in mouse serum, further verifying the excellent biocompatibility of supraclusters (Supplementary Fig. 16).",2026-06-07T02:20:35+00:00
30870,toxicity_endpoint,24,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The 20-mer ASO including only DNA (ASO1) and the 20-mer ASO with two LNAs (ASO2) induced high acute CNS toxicity in the acute toxicity scoring system compared with PBS (Video S1), and this toxicity persisted for 4 h after ICV administration.",2026-06-07T02:20:35+00:00
30871,toxicity_endpoint,25,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,decreased the severity of adverse events in a dose-dependent manner,2026-06-07T02:20:35+00:00
30872,toxicity_endpoint,26,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The final MTT assays were performed in non-tumor human fibroblast cell line Lep3 (Figure 8). The experiment was conducted to measure the cell toxicity and cell proliferation of all the designed pVEC-ASOs.,2026-06-07T02:20:35+00:00
30873,toxicity_endpoint,27,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,no systemic toxicity was observed in major organs.,2026-06-07T02:20:35+00:00
30874,toxicity_endpoint,28,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,CT102 showed safety and tolerability in participants with advanced primary liver cancer. The maximum tolerated dose of a single dose of CT102 was 3.96 mg/kg.,2026-06-07T02:20:35+00:00
30875,toxicity_endpoint,29,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40074308; Rejected: reported cytotoxicity is specific HeLa tumor-cell killing from STAT3-siRNA gene silencing, an anticancer efficacy readout excluded from toxicity curation.",2026-06-07T02:20:35+00:00
30876,toxicity_endpoint,30,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 39263399; weak/generic or abstract-limited support for general safety/cytotoxicity.,2026-06-07T02:20:35+00:00
30877,toxicity_endpoint,31,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The GBE-PLL-SLNPs had an average size of 93.2 nm and demonstrated enhanced binding and protection of the siRNA from enzyme digestion, with minimal cytotoxicity in HEK293 (<10%) and SH-SY5Y cells (<15%).",2026-06-07T02:20:35+00:00
30878,toxicity_endpoint,32,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Results indicated that mouse body weights were generally stable during the dosing period, and histologic analysis data showed no apparent damage or lesions in major organs (Fig. S8c-S8d).",2026-06-07T02:20:35+00:00
30879,toxicity_endpoint,33,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No significant body weight loss was observed following administration of SWNT-PL-PEG-S-S-siLUC to the HCT-116 xenograft in BALB/C nude mice.,2026-06-07T02:20:35+00:00
30880,toxicity_endpoint,34,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The introduction of phosphorothioate oligonucleotides does not have significant additional destructive effects on the liver and kidneys of animals.,2026-06-07T02:20:35+00:00
30881,toxicity_endpoint,35,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Myocardial I/R swine receiving miR-125a-5p agomir show no alterations in arrhythmic occurrences and serum chemistries,2026-06-07T02:20:35+00:00
30882,toxicity_endpoint,36,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,serological disease biomarkers of liver (alanine aminotransferase and alkaline phosphatase) (Figure 5I) and kidney (urea) (Figure 5K) were unchanged in all treated ADO2 mice compared with the WT controls.,2026-06-07T02:20:35+00:00
30883,toxicity_endpoint,37,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"repeated intramuscular administrations with Mstn siRNA or Mlycd siRNA loaded into red blood cell extracellular vesicles result in inhibition of Mstn or Mlycd gene expression, increased muscle growth, and prevention of cachexia in cancer-bearing mice without considerably systemic toxicity and inflammation.",2026-06-07T02:20:35+00:00
30884,toxicity_endpoint,38,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The toxic ASOs were found to reduce consciousness and locomotor function in mice in a dose-dependent manner.,2026-06-07T02:20:35+00:00
30885,toxicity_endpoint,39,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,reduced serum AST/ALT levels by 0.3,2026-06-07T02:20:35+00:00
30886,toxicity_endpoint,40,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The increased levels of ALT, AST and GLDH observed in animals treated with the parent D1 were completely normalized with D16, which closely mimicked that of the saline control (Figure 4D).",2026-06-07T02:20:35+00:00
30887,toxicity_endpoint,41,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 35917865; weak/generic or abstract-limited support for general safety/transcriptome toxicity.,2026-06-07T02:20:35+00:00
30888,toxicity_endpoint,42,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Mice treated with siLuc-ALC-0315 had significantly higher serum levels of ALT and bile acids,2026-06-07T02:20:35+00:00
30889,toxicity_endpoint,43,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"As shown in Figure 8B, no noticeable hemolysis was found for SSNs and PEG-SSNs compared to the control group.",2026-06-07T02:20:35+00:00
30890,toxicity_endpoint,44,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36365241; Rejected: LDH/cell-death readouts are docetaxel-induced prostate cancer cell killing and siRNA knockdown efficacy, not a safety/tolerability endpoint under the toxicity contract.",2026-06-07T02:20:35+00:00
30891,toxicity_endpoint,45,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Prior the evaluation of internalization and antisense inhibition of luciferase, we evaluate the potential toxicity of GalNAc-oligonucleotides by using MTT assay at 60 nM, 120 nM and 300 nM oligonucleotide concentration after 24 h.",2026-06-07T02:20:35+00:00
30892,toxicity_endpoint,46,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"At used concentration for cell experiments in this study (<0.2 mg/mL), the cell survival rate was all above 95%, which indicates that these NDs have high bio-safety.",2026-06-07T02:20:35+00:00
30893,toxicity_endpoint,47,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Efficiency of restoration of CYP3A5 activity by the 3A5*3 PMO was donor-dependent (Donor 3; See Supplemental Table 1), and was not related to cellular toxicity, as PMO treatments did not alter normal PTEC morphology (see Supplemental Fig. 9).",2026-06-07T02:20:35+00:00
30894,toxicity_endpoint,48,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Histopathological examination revealed mild injury with degeneration, karyomegaly, single-cell necrosis, and vacuolation in proximal tubules in both animals dosed at 30 mg/kg.",2026-06-07T02:20:35+00:00
30895,toxicity_endpoint,49,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Microscopically, vacuoles and basophilic granules in the proximal tubules were observed in the kidneys fixed with NBF.",2026-06-07T02:20:35+00:00
30896,toxicity_endpoint,50,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"I.c.v. injection of maximum dose (1,800 ng) of REPU910 had no adverse effect on mouse phenotypes, including motor function, growth, and survival.",2026-06-07T02:20:35+00:00
30897,toxicity_endpoint,51,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,LNPssPalmO-Phe–ASOap induced severe hepatotoxicity when injected at a dose of 0.37 mg/kg,2026-06-07T02:20:35+00:00
30898,toxicity_endpoint,52,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The incidence and mean percentage of doses leading to ISR, LCRIS, and FLR events were significantly lower in the test group, compared with mipomersen (Table 3 and Fig. 2).",2026-06-07T02:20:35+00:00
30899,toxicity_endpoint,53,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,H&E staining revealed that there was no discernible abnormality observed in dual-RGD protein-treated groups compared with the saline-treated control.,2026-06-07T02:20:35+00:00
30900,toxicity_endpoint,54,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No changes were found in the levels of these three renal function markers 7 days post-treatment which indicates that PMO–P6 is not toxic to the kidney at the doses tested,2026-06-07T02:20:35+00:00
30901,toxicity_endpoint,55,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Serum AST, ALT, Cr and BUN levels indicated no significant differences in all treated groups compared to negative control (PBS treated group) (Additional file 1: Table S5).",2026-06-07T02:20:35+00:00
30902,toxicity_endpoint,56,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,ASO FR7S-G showed the best potency but was extremely toxic at all doses which made it difficult to calculate an ED50 for CXCl12 mRNA reduction (Figure 3).,2026-06-07T02:20:35+00:00
30903,toxicity_endpoint,57,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The LNPs comprising 306-O12B-3 were well tolerated at all dose levels and observed no clinically significant change in mouse behavior, spleen size, and key hepatotoxic or nephrotoxic parameters (Table 1).",2026-06-07T02:20:35+00:00
30904,toxicity_endpoint,58,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In vivo and in vitro assays revealed complement activation, prolonged coagulation times, and platelet activation, correlating with the observed toxicity.",2026-06-07T02:20:35+00:00
30905,toxicity_endpoint,59,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Indeed, mild histopathological abnormalities were observed in the renal cortex of one rat treated with GalNac AON-B in a 2-week study (Figure 2A).",2026-06-07T02:20:35+00:00
30906,toxicity_endpoint,60,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In the rat, hepatotoxic siRNAs (siRNA-1 shown here) had hepatocellular degeneration (bracketed area), increased sinusoidal cells due to Kupffer cell hyperplasia and/or leukocyte infiltration (#), single cell necrosis (*), increased mitoses (^), and hepatocellular vacuolation (arrow).",2026-06-07T02:20:35+00:00
30907,toxicity_endpoint,61,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"This in vitro assay accurately reflects in vivo findings and relates hepatotoxicity to RNase H1 activity, off-target RNA downregulation, and LNA-ASO-binding affinity.",2026-06-07T02:20:35+00:00
30908,toxicity_endpoint,62,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"elevation of EGF in the supernatant of PTEC-TERT1 is most likely a result of dysfunctional uptake by EGFR rather than a stimulated production and secretion of EGF. We verified this hypothesis by confirming that PTEC-TERT1 efficiently deplete EGF from the medium within 72 hr (Figure 3A), express EGFR, and do not express detectable level of EGF even after exposure to AONs (Figure 3B). In addition, we compared the EGF profile of AON-treated PTEC-TERT1 in the presence and absence of extracellular EGF in the medium and observed that accumulation of soluble EGF occurred only when the medium was supplemented with EGF (Figure 3C). To visualize the capacity of AON-treated cells to internalize extracellular EGF, PTEC-TERT1 were exposed to AONs for 6 days, incubated overnight without EGF, and incubated 10 min at 37°C with a fluorescently labeled EGF (EGF-488) in AON-free medium (scheme Figure 3D). EGF uptake and intracellular accumulation was visible in the form of green foci in vehicle-treated cells and was fully blocked by simultaneous incubation with cetuximab, a monoclonal antibody that blocks EGF binding to EGFR19 (Figure 3D, upper panels). AON-A-treated cells normally accumulated EGF-488, whereas pre-exposure to toxic AON-D, AON-B, AON-C, and AON-E significantly reduced the number of EGF-488 foci (Figure 3D, lower panels; see Figure S6 for quantification). The decreased number of intracellular EGF foci together with the accumulation of EGF in the medium suggest that EGF uptake is dysfunctional in toxic AON-treated PTEC-TERT1 cells. To determine whether AON-mediated alterations in EGF transport are restricted to a renal epithelial cell model, we replaced PTEC-TERT1 with human primary hepatocytes, a cell model that is competent for gymnotic uptake of AONs,20 expresses EGFR but is not dependent on EGF for in vitro proliferation and survival (Figure S7). Human hepatocytes cultivated and seeded in a conventional EGF-free medium were exposed to safe and tubulotoxic AONs along with 10 ng/mL of EGF. Intracellular ATP and extracellular EGF were measured concomitantly after 3 days of AON exposure. AON-B and AON-C showed significantly elevated EGF levels whereas AONs D and E had minimal changes in EGF (Figure 3E). AON-C did not lead to a substantial reduction in intracellular ATP in human hepatocytes despite strong EGF elevation, thus uncoupling the two readouts and implying that reduced EGF uptake is not solely caused by a general cellular deterioration. In addition, we exposed the ARPE-19 retinal pigment epithelial cell line to AONs in cell medium supplemented with EGF. We observed an accumulation of EGF in the supernatant of AON-C-treated ARPE-19 associated with a decrease in intracellular ATP (Figure 3F). Interestingly, ARPE-19 did not show signs of cytotoxicity in response to AON-B and AON-E, thus highlighting the importance of choosing the most appropriate and responsive cell model to fully capture the toxicity potential of AONs with correlation to histopathology findings. Blockage of EGF-Induced and EGFR-Dependent Cellular Activity by Toxic AONs Following the finding that tubulotoxic AONs impair EGF uptake, we assessed whether tubulotoxicity is correlated with the amount of extracellular EGF in the medium. PTEC-TERT1 were grown until confluence in regular EGF-containing medium (10 ng/mL) and measurements of intracellular ATP and extracellular EGF accumulation were performed after simultaneous incubation with AON along with 0, 1, 3, 10, 30, or 100 ng/mL of EGF. This experiment showed that regulation of intracellular ATP levels in confluent, non-dividing PTEC-TERT1 is dependent on EGF concentration (Figure 4A). Remarkably, the toxicity profile of AONs D, B, and C was no longer observed at 0 and 1 ng/mL of EGF, and noticeable differences between innocuous and toxic AONs required 10 ng/mL or higher concentrations of EGF (Figure 4A). Importantly, AON target reduction was not affected by the presence or absence of EGF (Figure 4B). These data suggest that toxic AONs may block EGF-dependent cellular energy production. To further investigate this hypothesis, we monitored the effect of AONs after inhibition of EGFR signaling with Cetuximab. Similar to toxic AONs, cetuximab alone reduced EGF-induced intracellular ATP (Figure 4C). The combination of AONs and cetuximab had little synergistic or additional effects on ATP levels, suggestive of a common mode of action via inhibition of EGFR signaling. To corroborate these observations, the toxicity profile of AONs was assessed in the presence of erlotinib, a small molecule inhibitor of EGFR kinase activity. In agreement with our hypothesis, the ATP profile of innocuous and toxic AONs was undistinguishable in EGFR-inactivated cells via erlotinib (Figure 4D). Altogether, these data provide strong evidence that inhibition of EGFR signaling may be a central mechanism of AON-induced cytotoxicity in PTEC models. Modulation of EGFR Trafficking and Signaling by Toxic AONs AONs are poly-anionic molecules capable of binding to cell surface proteins and growth factors,21, 22 and it is conceivable that direct AON/EGF or AON/EGFR interactions initiate a negative regulation of EGFR that progressively leads to weakening of EGFR activity and decreased cellular activity. We assessed the direct interactions of five selected AONs with EGF and the extracellular domain of EGFR, separately and in combination, using label-free surface plasmon resonance (SPR). Despite robust interaction between EGF and EGFR, no direct AON/protein interaction could be detected between any of the five tested AONs and EGF or EGFR (Figure S8). Moreover, the data suggest that AONs did not interfere with the binding of EGF to EGFR in a cell-free system. We therefore used a fluorescence-based cellular assay that preserves the native conformation of membrane-bound receptors to visualize the binding of EGF to EGFR and the internalization of the EGF/EGFR complex. Briefly, EGF-starved PTEC-TERT1 were exposed to innocuous and toxic AONs in the presence of a fluorescently labeled EGF (EGF-488) for 10 min on ice to prevent internalization from the plasma membrane. PTEC-TERT1 cells were fixed and EGFR was visualized by immuno-detection. Binding of EGF-488 to the cellular membrane was evident for all conditions including PTEC-TERT1 exposed to toxic AONs (Figure 5A, upper panels). Addition of cetuximab completely abolished the binding of EGF-488 to the cell membrane and thereby confirmed the specific and effective binding of EGF-488 to EGFR for all treatments (Figure 5A, lower panels). Next, to visualize the internalization of EGF/EGFR, PTEC-TERT1 were incubated with EGF-488 at 37°C. Cellular uptake of EGF-488 was evident in both the vehicle and AON-exposed PTEC-TERT1 (Figure 5B, upper panels) and exclusively mediated by EGFR because the addition of cetuximab completely abolished the internalization of EGF-488 in all conditions (Figure 5B, lower panels). In agreement with this image-based assay, quantification by flow cytometry showed similar EGF-488 uptake by PTEC-TERT1 in the presence of innocuous and toxic AONs (Figure S9). We conclude that these AONs do not significantly interfere with EGF binding to EGFR and that simultaneous acute incubation with EGF and AONs does not directly block EGF uptake. Intriguingly, in cells exposed to AONs D, B, C, and E, EGFR was internalized in the presence of cetuximab and was not associated with any detectable EGF-488 signal (Figures 5B and 5C, arrows). In all conditions except vehicle and AON-A, a subpopulation of cells showed a perinuclear distribution of EGFR (Figure 5C, arrows). We developed a method to quantify the presence of EGFR foci located at a fixed distance from the nucleus (perinuclear EGFR) and determined the mean intensity of perinuclear EGFR per cell. In vehicle-treated cells, co-incubation with EGF and cetuximab maintained EGFR at the cell membrane (Figure 5C, arrow), which is translated as a left shift on the quantification graph of perinuclear EGFR (Figure 5D). Incubation with toxic AONs significantly disrupted the cetuximab-dependent distribution of EGFR between the plasma membrane and the perinuclear compartment: the amount of EGFR at the cell membrane was diminished and accumulation of perinuclear EGFR was increased (Figures 5D and S10). The molecular nature of perinuclear EGFR foci caused by toxic AONs, unveiled here by the use of cetuximab, remains to be elucidated in future studies. Nevertheless, these observations suggest that toxic AONs induce ligand-independent internalization of EGFR. Next, the acute effect of AONs on EGFR kinase activity was determined by immunoblot analysis of AKT and ERK1/2 phosphorylation. PTEC-TERT1 were exposed to EGF and AONs and harvested after 10 min of incubation. Downregulation of phosphorylation of AKT by toxic AON-C and E was readily apparent after 10 min of exposure (Figures 5E, left panel, and S11). The effects of toxic AON-B, AON-C, and AON-E on phosphorylation of AKT and ERK1/2 were more pronounced after 24 and 72 hr of AON exposure (Figures 5E, middle and right panels, and S11), likely reflecting a reduced steady-state level of EGFR signaling in toxic AON-exposed cells. Such reduction is not caused by a general toxicity effect, since the nephrotoxicant cyclosporine A (CysA) did not reduce the phosphorylation level of AKT and ERK1/2 relative to the GAPDH protein loading control (Figure S12). The effect of AON-D on EGFR activity could not be detected by measurement of AKT and ERK1/2 phosphorylation level, hypothetically due to compensatory signals or feedback mechanisms, which would also explain the variable profile of AON-D across in vivo studies in rodents (Table 1; Figure S5). Together, these results reveal acute effects of toxic AONs on EGFR cellular distribution and kinase activity and suggest that reduced EGF uptake in toxic AON-exposed PTEC-TERT1 occurs progressively as a consequence of dysfunctional EGFR trafficking and signaling. Impairment of an EGF Transcriptional Signature by Toxic AONs In order to further investigate the effects of AONs on EGF-dependent responses at early time points, we used molecular phenotyping, a recently introduced technology to infer human pathway activities by quantifying expression of pathway-reporter genes with next-generation sequencing.23 PTEC-TERT1 were treated with innocuous and toxic AONs in the presence or absence of EGF for 6 hr, total RNA was isolated and pathway reporter genes were quantified based on sequencing of predefined amplicons.24 To derive a list of genes that are modulated by extracellular EGF in PTEC-TERT1 (EGF signature herein), we compared expression profiles of vehicle-treated cells with and without EGF and identified 66 genes that are consistently positively or negatively modulated by EGF. We performed functional enrichment analysis of EGF signatures and observed that genes induced by EGF have versatile biological functions such as signal transduction, cytokine production, response to oxidative stress and hypoxia, defense response, and fatty acid metabolism (Figure 6A). It is worth mentioning that no gene set directly associated with cell cycle or apoptosis passed the significance threshold. The signature allowed us to interrogate whether AON treatments impaired EGF signaling. Cluster analysis of EGF-induced changes of the signature revealed that treatment with toxic AONs altered the downstream expression output of EGF signaling as early as 6 hr compared with vehicle control. At 30 and 100 μM, the innocuous AON-A and vehicle clustered together while AON-B, AON-C, AON-D, and AON-E displayed substantially different profiles (Figure 6B). Next, we used heatmap visualization of expression changes to compare the effects of AONs on the EGF signature after 6 hr of exposure at 30 μM. The vehicle control highlights positively and negatively regulated genes in the EGF versus no-EGF condition (Figure 6C). The EGF-induced signature (red signals) is preserved in AON A-treated cells consistent with the innocuous profile observed in vitro and in vivo under our experimental conditions. Interestingly, several genes strongly downregulated by the presence of EGF (blue signals) were less modulated in the presence of AON-A, suggesting a general effect of AONs that is not deleterious for normal cellular function. Remarkably, AON-B, AON-C, AON-D, and AON-E almost abolished the EGF signature of both positive and negative EGF-dependent modulation (Figure 6C). Interestingly, all four potentially toxic AONs showed a similar profile in this analysis, including AON-D. Therefore, molecular phenotyping analysis of EGF-induced signature is a sensitive and powerful approach to detect the tubulotoxicity potential of AONs. Overall, molecular phenotyping data revealed that only known toxic AONs inhibit EGF signaling as early as 6 hr after treatment, consistent with molecular and cellular analyses of EGFR signaling. Safety Assessment across Pre-clinical AON Series Using Extracellular EGF To validate the use of EGF as a biomarker in discovery and pre-clinical kidney safety screens, we reviewed pre-clinical studies available to our group and selected an additional 12 LNA-AON compounds targeting MYD88 or BCL11A with reported gross anatomical changes in mouse kidneys or histopathological findings in rat kidneys (Table S1). Two additional innocuous AONs were included as controls. For all 14 AONs",2026-06-07T02:20:35+00:00
30909,toxicity_endpoint,63,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The Acsl1 gapmer used in this study significantly increases plasma ALT/AST levels within a few days after a single administration.,2026-06-07T02:20:35+00:00
30910,toxicity_endpoint,64,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We observed highly selective transcript knockdown in mice treated with non-hepatotoxic LNA ASOs, while the levels of many unintended transcripts were reduced in mice treated with hepatotoxic LNA ASOs.",2026-06-07T02:20:35+00:00
30911,toxicity_endpoint,65,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Analysis of serum biochemical indices including aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase, serum creatinine, urea, urinary kidney injury molecule-1 and serum glucose, and histology revealed no evidence of liver or renal toxicity, or abnormal increase in serum glucose levels (Supplementary Fig. 2a–d, n=6) and no inflammatory cell activation (Supplementary Fig. 2e, n=6)",2026-06-07T02:20:35+00:00
30912,toxicity_endpoint,66,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Over 80 unique 3-8-3 gapmers targeting the mRNAs for human Apoc3, Crtc2 or GR were tested for tolerability in vivo.",2026-06-07T02:20:35+00:00
30913,toxicity_endpoint,67,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"A total of 2 participants reported events within the AESI of ALT increases; 1 participant in the HCP‐administered PFS SSD group, and 1 participant in the self‐administered PFS SSD with training group each reported an AE of ALT increase and aspartate aminotransferase increase",2026-06-07T02:20:35+00:00
30914,toxicity_endpoint,68,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No infusion-related reactions or toxicity was observed.,2026-06-07T02:20:35+00:00
30915,toxicity_endpoint,69,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Systemic inflammatory responses were assessed by cytokine profiling, which revealed no significant induction of IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, TNF-α, IFN-α, or IFN-γ following siCD36@MSNs@Plt treatment (Fig. S4O)",2026-06-07T02:20:35+00:00
30916,toxicity_endpoint,70,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No significant toxicity was observed in vital organs (ALT/AST levels, P>0.05; histopathology scores, P>0.05).",2026-06-07T02:20:35+00:00
30917,toxicity_endpoint,71,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"There were no reported TEAEs that led to withdrawal from the trial, no serious TEAEs or treatment-induced SAEs occurred, and no deaths were reported during the study period.",2026-06-07T02:20:35+00:00
30918,toxicity_endpoint,72,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The enzymes ALP, ALT, and AST, remained at the same level in all treated groups when compared to the healthy group (Fig. 6g–i), indicating the absence of inflammation and liver toxicity",2026-06-07T02:20:35+00:00
30919,toxicity_endpoint,73,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40574039; Reject: passage reports in vitro Leu-Fect transfection reagent cytotoxicity with control siRNA in a cell model; no named therapeutic oligonucleotide administered/measured, so it fails the in-scope therapeutic oligo gate.",2026-06-07T02:20:35+00:00
30920,toxicity_endpoint,74,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"These findings demonstrate that the toxicity of the three new LNPs was consistent across all three cell types, with no significant change in cell viability within the concentration range tested.",2026-06-07T02:20:35+00:00
30921,toxicity_endpoint,75,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Compared with those in the control group, no significant differences in tissue integrity or cellular morphology were observed in the experimental group (Fig. 7).",2026-06-07T02:20:35+00:00
30922,toxicity_endpoint,76,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Histological analysis revealed no treatment-related liver abnormalities, including fibrosis, necrosis, or hepatocellular degeneration (Figure 3G).",2026-06-07T02:20:35+00:00
30923,toxicity_endpoint,77,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 39896757; pmc_full_text evidence was direct but less than full primary-detail confidence for renal/renal safety.,2026-06-07T02:20:35+00:00
30924,toxicity_endpoint,78,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,TEAEs associated with hepatic safety were balanced between the treatment groups (inclisiran group: 12.4%; placebo group: 10.9%).,2026-06-07T02:20:35+00:00
30925,toxicity_endpoint,79,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"LNA-i-miR-221 was well tolerated at all dose levels, with no grade 3–4 dose-limiting toxicity (DLT) observed in any cohort.",2026-06-07T02:20:35+00:00
30926,toxicity_endpoint,80,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36302886; Out of scope under v2: the passage evaluates generic lipid nanoparticle/liposome reference materials and cytotoxic profiles, not a named therapeutic oligonucleotide candidate.",2026-06-07T02:20:35+00:00
30927,toxicity_endpoint,81,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Cytotoxicity was only elevated in cells treated with the positive control digitonin, indicating the ASOs tested do not display cytotoxic effects at 30 nM (Figure S2B).",2026-06-07T02:20:35+00:00
30928,toxicity_endpoint,82,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 24806225; Out of scope under v2: the vivo-morpholinos were used as laboratory gene-silencing tools for Anxa6/Casq1 rather than named therapeutic oligonucleotide candidates, despite observed mortality.",2026-06-07T02:20:35+00:00
30929,toxicity_endpoint,83,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Common treatment-emergent adverse reactions (TEAR) in the imetelstat arm, including laboratory abnormalities, were decreased platelets, white blood cells, and neutrophils, increased AST, alkaline phosphatase, and ALT",2026-06-07T02:20:35+00:00
30930,toxicity_endpoint,84,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,There was no evidence of increased risk for grade 4 thrombocytopenia or severe renal events with increased duration of inotersen exposure.,2026-06-07T02:20:35+00:00
30931,toxicity_endpoint,85,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Considering all the cytokines evaluated, these data show that PS-ASOs segregate into multiple classes based on the extent of innate immune activation and the kinetics of cytokine induction",2026-06-07T02:20:35+00:00
30932,toxicity_endpoint,86,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Among 25 participants, SRN001 was generally well tolerated.",2026-06-07T02:20:35+00:00
30933,toxicity_endpoint,87,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No in vivo toxicity observed in mice treated with LNPs encapsulating siRNAs, as analyzed with biochemical indicators in vital organs.",2026-06-07T02:20:35+00:00
30934,toxicity_endpoint,88,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,These data indicated that SNA2-ASO was safer than MOE-ASO in terms of adverse hepatic and renal events.,2026-06-07T02:20:35+00:00
30935,toxicity_endpoint,89,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 40243849; pmc_full_text evidence was direct but less than full primary-detail confidence for renal/renal safety.,2026-06-07T02:20:35+00:00
30936,toxicity_endpoint,90,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"CpG-ssSTAT3ASOLNA treatment increased average ATSS score across all tested doses (0.1-1 mg/kg) with marked signs of toxicity, including decreased consciousness and impaired movement at the highest dose",2026-06-07T02:20:35+00:00
30937,toxicity_endpoint,91,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The rates of drug‐related grade ≥ 3, serious, or fatal TEAEs were similar or lower in ADA‐positive versus ADA‐negative patients.",2026-06-07T02:20:35+00:00
30938,toxicity_endpoint,92,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 41625362; pmc_full_text evidence was direct but less than full primary-detail confidence for immunotoxicity/immune activation.,2026-06-07T02:20:35+00:00
30939,toxicity_endpoint,93,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The nanodevice exhibited good in vivo biosafety, with no observed toxicity to the liver or kidneys, and no abnormalities in serum biochemical indices (Supplementary Fig. 22).",2026-06-07T02:20:35+00:00
30940,toxicity_endpoint,94,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 40977834; pmc_full_text evidence was direct but less than full primary-detail confidence for renal/renal safety.,2026-06-07T02:20:35+00:00
30941,toxicity_endpoint,95,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 40380202; pmc_full_text evidence was direct but less than full primary-detail confidence for immunotoxicity/immune activation.,2026-06-07T02:20:35+00:00
30942,toxicity_endpoint,96,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,a 4-week toxicology study in cynomolgus monkeys showed that anti-ANGPTL4 ASO treatment (weekly subcutaneous injections of up to 30 mg/kg) was well tolerated and did not induce any adverse effects,2026-06-07T02:20:35+00:00
30943,toxicity_endpoint,97,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"H&E staining also revealed no noticeable pathological abnormalities in the eyes (including eyeball, cornea, and retina) (Figures 6F and 7E) and major organs (including heart, liver, spleen, lung, and kidney)",2026-06-07T02:20:35+00:00
30944,toxicity_endpoint,98,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 39065632; previous accept was too weak/generic for renal/renal safety in siRNA candidate from PMID 39065632. Basis checked: Full-text MTT assay measured cytotoxicity of the siRNA delivery dendrimers, including a kidney cell line; accepted as delivery-product toxicity evidence but graded weak/generic for a non-sp?",2026-06-07T02:20:35+00:00
30945,toxicity_endpoint,99,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The data showed no detectable alteration of parameters in D-siRNA-injected mice compared with PBS-injected mice,2026-06-07T02:20:35+00:00
30946,toxicity_endpoint,100,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Adverse events associated with FLRs were more strongly correlated with the inflammation signals predicted by the BJAB assay than adverse events associated with injection site reactions.,2026-06-07T02:20:35+00:00
30947,toxicity_endpoint,101,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,ASO delivery via both gymnosis and LNPs triggered an ASO-mediated microgliosis response that was evident by increased Iba1 signal and transcriptional activation of inflammatory pathways in the brain.,2026-06-07T02:20:35+00:00
30948,toxicity_endpoint,102,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Despite a higher DOX concentration and residence time we did not observe any systemic toxicities in the nanoparticle groups.,2026-06-07T02:20:35+00:00
30949,toxicity_endpoint,103,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 37273265; previous accept was too weak/generic for hepatic/hepatotoxicity in siRNA candidate from PMID 37273265. Basis checked: Full-text in vitro delivery-formulation results measure A549 viability after siRNA lipoplex exposure; evidence is generic formulation toxicity rather than a named clinical oligo.,2026-06-07T02:20:35+00:00
30950,toxicity_endpoint,104,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"across the single and multiple dose cohorts, 197 treatment‐emergent adverse events were reported, with 99% and 65% classified as mild in severity and local injection site reactions, respectively.",2026-06-07T02:20:35+00:00
30951,toxicity_endpoint,105,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,104838 and 501861 triggered moderate platelet activation and sykdependent formation of platelet-leukocyte aggregates.,2026-06-07T02:20:35+00:00
30952,toxicity_endpoint,106,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"When treated with either exosomes alone, EPM, or EPM loaded with nucleic acids as used in this study, HEK293T cells had similar survival as compared to untreated cells, indicating the lack of detectable cytotoxicity.",2026-06-07T02:20:35+00:00
30953,toxicity_endpoint,107,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Our study found that some lipid conjugates, particularly DCA and PC-DCA, support higher siRNA accumulation than cholesterol in extra-hepatic tissues, including muscle, heart, fat and lung, without causing overt toxicity.",2026-06-07T02:20:35+00:00
30954,toxicity_endpoint,108,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,phosphorothioate (PS)-ONs can bind to platelet proteins such as platelet collagen receptor glycoprotein VI (GPVI) and activate human platelets in vitro to various extents.,2026-06-07T02:20:35+00:00
30955,toxicity_endpoint,109,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,HA/PEIss@siNC (HPssNC) at various concentrations revealed no significant changes in cell viability (Fig. 2F).,2026-06-07T02:20:35+00:00
30956,toxicity_endpoint,110,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Median percent change from baseline in eGFR was 2.5%, indicating preservation of renal function.",2026-06-07T02:20:35+00:00
30957,toxicity_endpoint,111,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,mean estimated glomerular filtration rate (egfr) remained stable (62–84.2 ml/min per 1.73 m2) to month 30.,2026-06-07T02:20:35+00:00
30958,toxicity_endpoint,112,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,HDOs significantly decreased C3a levels compared to ASOs in both base lengths in the ex vivo assay (Figures 1E and 1F).,2026-06-07T02:20:35+00:00
30959,toxicity_endpoint,113,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Laboratory data on renal function (including cystatin C) were followed for the whole length of the study, with no clinically significant findings being reported.",2026-06-07T02:20:35+00:00
30960,toxicity_endpoint,114,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Safety was similar to that observed in the previous 24-week trial, which was predominantly mild.",2026-06-07T02:20:35+00:00
30961,toxicity_endpoint,115,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,when tested in primary mouse hepatocytes and human proximal tubular epithelial cells treatment with c1 resulted in “severe toxicity” in both cell systems.,2026-06-07T02:20:35+00:00
30962,toxicity_endpoint,116,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Adverse events and serious adverse events did not differ between the inclisiran and placebo groups throughout the study.,2026-06-07T02:20:35+00:00
30963,toxicity_endpoint,117,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No signs of hepatotoxicity were observed under the conditions used.,2026-06-07T02:20:35+00:00
30964,toxicity_endpoint,118,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"in spleen cells, no noticeable cytotoxicity was observed at concentrations up to 100 µm (figure 2).",2026-06-07T02:20:35+00:00
30965,toxicity_endpoint,119,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 41984862; weak/generic or abstract-limited support for neurological/neurotoxicity.,2026-06-07T02:20:35+00:00
30966,toxicity_endpoint,120,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Remarkably, both ALT and creatinine concentrations remained comparable to control levels, indicating that our treatment did not induce any significant liver or kidney toxicity (Figure S8B,C, Supporting Information).",2026-06-07T02:20:35+00:00
30967,toxicity_endpoint,121,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 41755009; pmc_full_text evidence was direct but less than full primary-detail confidence for renal/renal safety.,2026-06-07T02:20:35+00:00
30968,toxicity_endpoint,122,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41810468; Reject under v2: the IVSA-siRNA modality is generated after intravenous injection of naked DNA plasmid genetic circuits that reprogram host liver, so the passage does not provide in-scope administered therapeutic oligonucleotide toxicity evidence.",2026-06-07T02:20:35+00:00
30969,toxicity_endpoint,123,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Collectively, these results indicate that the chiral MnO2 nanozymes did not induce detectable adaptive immune activation and exhibited excellent biosafety in vivo.",2026-06-07T02:20:35+00:00
30970,toxicity_endpoint,124,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,in vivo studies validated that the nano-delivery system exhibits potent antitumor efficacy in a 4T1 murine breast cancer model while maintaining a favorable biosafety profile.,2026-06-07T02:20:35+00:00
30971,toxicity_endpoint,125,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No significant adverse effects on platelet counts or renal functions were observed.,2026-06-07T02:20:35+00:00
30972,toxicity_endpoint,126,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No safety concerns were identified in participants with mild HI or in matched controls.,2026-06-07T02:20:35+00:00
30973,toxicity_endpoint,127,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"RO7239958 was generally well tolerated in healthy volunteers; transaminase elevations occurred at the highest doses, including one reversible Grade 3 elevation.",2026-06-07T02:20:35+00:00
30974,toxicity_endpoint,128,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 40654713; weak/generic or abstract-limited support for neurological/neurotoxicity.,2026-06-07T02:20:35+00:00
30975,toxicity_endpoint,129,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"ON30 effectively reduced liver Nr3c1 expression but caused significant hepatotoxicity, as evidenced by elevated ALT and AST levels and reduced body weight",2026-06-07T02:20:35+00:00
30976,toxicity_endpoint,130,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"RmHnC-DOPE LNPs did not induce any abnormal elevations in biochemical parameters, indicating well-preserved hepatic and renal functions.",2026-06-07T02:20:35+00:00
30977,toxicity_endpoint,131,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"cell viabilities remained above this threshold, indicating that all nanocomplexes were non-toxic in all cells.",2026-06-07T02:20:35+00:00
30978,toxicity_endpoint,132,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,indicating no renal injury or abnormalities in renal function.,2026-06-07T02:20:35+00:00
30979,toxicity_endpoint,133,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41256914; Reject: in-scope gate fails because the passage uses GAPDH/control siRNA as an oral-delivery benchmark, not a named therapeutic oligonucleotide; non-accept quote set to NONE.",2026-06-07T02:20:35+00:00
30980,toxicity_endpoint,134,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We have successfully demonstrated that by optimizing the PEI ratio with close to neutral surface charge, we were able to reduce PEI-induced cytotoxicity without compromising the transfection efficiency.",2026-06-07T02:20:35+00:00
30981,toxicity_endpoint,135,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"no obvious toxicity-related lesions were observed in the heart, liver, spleen, lung, and kidneys of mice treated with",2026-06-07T02:20:35+00:00
30982,toxicity_endpoint,136,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"After implementation of the AT-based dose regimen, there were no thrombotic events, and a reduction in the incidence of elevated transaminases and biliary events was reported.",2026-06-07T02:20:35+00:00
30983,toxicity_endpoint,137,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 41299672; pmc_full_text evidence was direct but less than full primary-detail confidence for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
30984,toxicity_endpoint,138,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Both tested nanoparticles proved to be less genotoxic when they were complexed with siRNA, showing a DNA disruption at levels below 10%",2026-06-07T02:20:35+00:00
30985,toxicity_endpoint,139,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40573259; Reject: in-scope gate fails because toxicity was measured during GFP/scrambled/model siRNA delivery optimization, not for a therapeutic oligonucleotide; non-accept quote set to NONE.",2026-06-07T02:20:35+00:00
30986,toxicity_endpoint,140,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"we observed no significant changes in the levels of biochemical indicators (including AST, ALT, BUN, and CRE-L) in the treatment groups relative to the model group, confirming the absence of damage to the normal liver and kidney functions",2026-06-07T02:20:35+00:00
30987,toxicity_endpoint,141,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,no significant toxicity of siSCR-loaded DDAB-cLNPs (siSCR@DDAB-cLNPs) was observed across all concentrations,2026-06-07T02:20:35+00:00
30988,toxicity_endpoint,142,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Clinical evaluations showed no significant effects on QTcF or other electrocardiogram parameters at 7.1 mg/kg.,2026-06-07T02:20:35+00:00
30989,toxicity_endpoint,143,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The CCK-8 assay results indicate that the cell viability of each experimental group exceeded 97%,2026-06-07T02:20:35+00:00
30990,toxicity_endpoint,144,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Atorvastatin had a higher ROR for type 2 diabetes (195.03) than inclisiran (0.95) and evolocumab, but it was not statistically significant.",2026-06-07T02:20:35+00:00
30991,toxicity_endpoint,145,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"no significant differences in the levels of ALT, AST, UREA, CRE, RBC, WBC, HGB, and PLT among the treatment groups.",2026-06-07T02:20:35+00:00
30992,toxicity_endpoint,146,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39829590; Reject: in-scope gate fails because the study uses generic/model siRNA nanocarrier complexation rather than an administered named therapeutic oligonucleotide; non-accept quote set to NONE.,2026-06-07T02:20:35+00:00
30993,toxicity_endpoint,147,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Regarding safety, the incidence of adverse events was 40.48%, with fever being the most common adverse reaction, occurring in 36.36% of cases.",2026-06-07T02:20:35+00:00
30994,toxicity_endpoint,148,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Lactate dehydrogenase (LDH) release assays in T98G glioblastoma cells demonstrated excellent biocompatibility of both dendritic families.,2026-06-07T02:20:35+00:00
30995,toxicity_endpoint,149,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,octa-guanidine-dendrimer-conjugated in vivo PMO-oligonucleotides (ivPMO) caused toxicity.,2026-06-07T02:20:35+00:00
30996,toxicity_endpoint,150,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"For the primary endpoint, no serious adverse events or clinically relevant laboratory abnormalities were reported.",2026-06-07T02:20:35+00:00
30997,toxicity_endpoint,151,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,There were no serious adverse events (SAEs) or suspected or unexpected serious adverse reactions (SUSARs).,2026-06-07T02:20:35+00:00
30998,toxicity_endpoint,152,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"toxicity studies in mice indicate that repeated administration of Gelasomes (up to 48 mg/kg BW) is well-tolerated with no notable changes in body weight, hematology, or serum chemistry.",2026-06-07T02:20:35+00:00
30999,toxicity_endpoint,153,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 38563414; weak/generic or abstract-limited support for hematologic/platelet/bleeding safety.,2026-06-07T02:20:35+00:00
31000,toxicity_endpoint,154,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The incidence of TEAEs associated with the liver was higher in the inclisiran sodium 300 mg group, but all were mild in severity.",2026-06-07T02:20:35+00:00
31001,toxicity_endpoint,155,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"For most of the tested cytokines, P(SpAA-co-DAA)3 treated mice showed similar or lower levels of inflammation than untreated mice (IL-23, IL-27, IFN-y, IL-12p70, IL-10, IFN-b).",2026-06-07T02:20:35+00:00
31002,toxicity_endpoint,156,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Pro-inflammatory type-I cytokines (IL-1β, TNF-α, INFγ, IL-6 and KC) measured in serum 4 h post-injection were markedly increased by bacterial LPS and InvLNPs (Figure 4). No significant induction was observed with uncoated and HA-coated NPs.",2026-06-07T02:20:35+00:00
31003,toxicity_endpoint,157,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,PAMAM-calix-dendrimers are low-toxic at the concentration required for efficient RNA binding.,2026-06-07T02:20:35+00:00
31004,toxicity_endpoint,158,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,HSN were biocompatible in hMSCs up to 300 µg/mL except for Cu2+ doped HSNs which were cytotoxic even at ~10 µg/mL.,2026-06-07T02:20:35+00:00
31005,toxicity_endpoint,159,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Animals that received high doses of the test oligonucleotide (i.e., four times the baseline dose) showed EEG abnormalities, with sharp spikes and waves consistent with seizures (Figure 4B), followed by tonic-clonic movements (Figure 4C).",2026-06-07T02:20:35+00:00
31006,toxicity_endpoint,160,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37538053; Reject: loaded passage provides efficacy/pharmacodynamic results and background statements about PMO low toxicity, but no primary measured toxicity or safety endpoint for the administered EEV-PMO product.",2026-06-07T02:20:35+00:00
31007,toxicity_endpoint,161,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We assayed liver and kidney biochemistry after administration of PB84 and observed no phenotype for the following biomarkers for toxicity: alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, blood urea nitrogen, creatinine, total serum protein, albumin, globulin, glucose, and bilirubin (Figure 2c).",2026-06-07T02:20:35+00:00
31008,toxicity_endpoint,162,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We assayed liver and kidney biochemistry after administration of PB84 and observed no phenotype for the following biomarkers for toxicity: alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, blood urea nitrogen, creatinine, total serum protein, albumin, globulin, glucose, and bilirubin (Figure 2.C).",2026-06-07T02:20:35+00:00
31009,toxicity_endpoint,163,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Neither CPP-AuNPs nor siRNA/CPP-AuNPs samples showed elevated cytotoxicity.,2026-06-07T02:20:35+00:00
31010,toxicity_endpoint,164,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35213032; Reject: loaded passage is a methods/chapter-style description of renal-toxicity assessment and lacks a primary observed/administered/measured ASO toxicity result.,2026-06-07T02:20:35+00:00
31011,toxicity_endpoint,165,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In rat and nonhuman primate 29-day toxicology studies, SLN360 was well tolerated at all doses.",2026-06-07T02:20:35+00:00
31012,toxicity_endpoint,166,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The cytotoxicity of LHHK LNPs increased with the higher dose, however higher doses of LHHK LNPs were less cytotoxic compared to Lipofectamine-2000 at some extent (Fig. 5B).",2026-06-07T02:20:35+00:00
31013,toxicity_endpoint,167,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"With a maximum exposure of 6.2 years, inotersen was not associated with any additional safety concerns or increased toxicity in the OLE study.",2026-06-07T02:20:35+00:00
31014,toxicity_endpoint,168,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35332222; Reject: passage concerns toxic 6mer seed cancer-cell killing/DISE efficacy screens, which the toxicity contract excludes as cancer-cell-killing cytotoxicity efficacy rather than therapeutic safety.",2026-06-07T02:20:35+00:00
31015,toxicity_endpoint,169,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Results in Fig. 4a demonstrated that there was no cytotoxicity for different particles.,2026-06-07T02:20:35+00:00
31016,toxicity_endpoint,170,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In SKOV3 cells, liposomes showed a dose‐dependent decrease in cell viability whereas this effect was not observed for hybrids (1:100 and 1:50) indicating increased biocompatibility of hybrids as compared to liposomes.",2026-06-07T02:20:35+00:00
31017,toxicity_endpoint,171,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36015328; Reject: loaded passage evaluates plasmid DNA vaccine LNP delivery and in-vitro LNP cytotoxicity, not an in-scope therapeutic oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31018,toxicity_endpoint,172,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"All animals survived up to the scheduled humane killing, and RTR5001 was clinically well-tolerated at 20 mg/kg/dose.",2026-06-07T02:20:35+00:00
31019,toxicity_endpoint,173,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"There were no deaths, dose reductions, abnormalities in laboratory parameters or vital signs, or casimersen‐related serious AEs.",2026-06-07T02:20:35+00:00
31020,toxicity_endpoint,174,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"There were no obvious histological differences between the major organs including heart, liver, spleen, lungs, and kidney of cRGD-NP/S, cRGD-PSH-NP/S, and saline-treated mice (Figure 8).",2026-06-07T02:20:35+00:00
31021,toxicity_endpoint,175,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Analysis of mean liver enzyme levels revealed no relevant changes during treatment.,2026-06-07T02:20:35+00:00
31022,toxicity_endpoint,176,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,accounted for more than 90%,2026-06-07T02:20:35+00:00
31023,toxicity_endpoint,177,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The no observed adverse effect level (NOAEL) in rats was 30 mg/kg based on reversible microscopic changes in liver,2026-06-07T02:20:35+00:00
31024,toxicity_endpoint,178,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,remained within normal reference values in mice treated with GalNAc-Stk25 ASO,2026-06-07T02:20:35+00:00
31025,toxicity_endpoint,179,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,induced neither hepatic nor renal toxicities,2026-06-07T02:20:35+00:00
31026,toxicity_endpoint,180,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Significant elevations in ALT (717 U/L) and AST (853 U/L) were observed,2026-06-07T02:20:35+00:00
31027,toxicity_endpoint,181,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"At least one adverse event occurred in 31/42 (74%) who received radavirsen, and 13/14 (93%) receiving placebo.",2026-06-07T02:20:35+00:00
31028,toxicity_endpoint,182,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No signs of abnormal behavior or change in body weight and overall condition were observed during treatment with any saponin/PMO polyplexes,2026-06-07T02:20:35+00:00
31029,toxicity_endpoint,183,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In the liver, minimal single cell necrosis was observed in 1 of 3 minipigs dosed at 20 mg/kg",2026-06-07T02:20:35+00:00
31030,toxicity_endpoint,184,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No signs of abnormal behavior or change in body weight and overall condition were observed during systemic treatment with PQ-formulated PMO,2026-06-07T02:20:35+00:00
31031,toxicity_endpoint,185,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,siRNA infusion did not change the number of DARPP32-positive neurons.,2026-06-07T02:20:35+00:00
31032,toxicity_endpoint,186,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,showed cell viability over 75%,2026-06-07T02:20:35+00:00
31033,toxicity_endpoint,187,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No hepatic toxicity, thrombocytopenia, or coagulation abnormalities were reported.",2026-06-07T02:20:35+00:00
31034,toxicity_endpoint,188,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Improved transfection efficiency and lower toxicity indicate the potential of the biodegradable PEA polymers as safe and efficient PMO delivery vectors,2026-06-07T02:20:35+00:00
31035,toxicity_endpoint,189,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,the viability of the cells treated with up to 800 nM equivalent oligonucleotides in nanoconjugates were over 90% of the control cells,2026-06-07T02:20:35+00:00
31036,toxicity_endpoint,190,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 39064553; pmc_full_text evidence was direct but less than full primary-detail confidence for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31037,toxicity_endpoint,191,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35221289; Reject: passage is a secondary review of ASO ADRs/toxicity, not a primary observed/administered/measured safety result.",2026-06-07T02:20:35+00:00
31038,toxicity_endpoint,192,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,There was no evidence of serious kidney toxicity.,2026-06-07T02:20:35+00:00
31039,toxicity_endpoint,193,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,both LNP-siMKK4 and GalNAc-LNP-siMKK4 induced less than 5% of hemolysis rate,2026-06-07T02:20:35+00:00
31040,toxicity_endpoint,194,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,MC3-based LNP-BioRNA treatment led to an 8% decrease in body weights and obvious hepatosplenomegaly,2026-06-07T02:20:35+00:00
31041,toxicity_endpoint,195,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42182416; Reject: passage supports ASO delivery/efficacy and biodistribution but provides no primary toxicity, safety, or tolerability result.",2026-06-07T02:20:35+00:00
31042,toxicity_endpoint,196,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,did not show significant cytotoxicity,2026-06-07T02:20:35+00:00
31043,toxicity_endpoint,197,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C as borderline: PMID 42170556; curator counted hepatic/hepatotoxicity for Gb3S; MC3-containing; Gb3 despite v2 exclusion. Low-confidence override; v2 note was: ungrounded: proposed viability result quote is not a verbatim span in the loaded passage; available text only states methods/safety summary, insufficient for accepted pr?",2026-06-07T02:20:35+00:00
31044,toxicity_endpoint,198,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41977470; Reject: SKR/quercetin is a traditional medicine/small-molecule study and SLC15A2 siRNA is used only as a mechanistic knockdown tool, not therapeutic oligo safety.",2026-06-07T02:20:35+00:00
31045,toxicity_endpoint,199,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Serum biochemistry further showed no significant hepatic or renal toxicity in treated mice,2026-06-07T02:20:35+00:00
31046,toxicity_endpoint,200,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41521235; Reject: SSR is a traditional medicine study and SIRT1 siRNA is a lab knockdown tool for mechanism, not a therapeutic oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31047,toxicity_endpoint,201,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41501598; Reject: PAX2/PAX8 siRNAs are used as in vitro knockdown tools in ADPKD mechanism/spheroid assays; no administered therapeutic oligo safety or toxicity endpoint is reported.,2026-06-07T02:20:35+00:00
31048,toxicity_endpoint,202,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"si097s-DV29PG5, si098-DV29PG5, and Zilebesiran had no effect on blood ALT, AST, or urea levels",2026-06-07T02:20:35+00:00
31049,toxicity_endpoint,203,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,blood biochemical analysis and H&E staining results showed that LNP-siTNF-α-HCQ did not damage blood cells and reduce liver and kidney functions,2026-06-07T02:20:35+00:00
31050,toxicity_endpoint,204,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"siRNA 30 induced elevated expression of multiple ISGs, including IFIT1, OAS1, and ISG20",2026-06-07T02:20:35+00:00
31051,toxicity_endpoint,205,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,both unmodified and modified-mannose MA/DC/MH_LNPs maintained cell viability close to 100% across the tested concentration range,2026-06-07T02:20:35+00:00
31052,toxicity_endpoint,206,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40418189; Reject: the passage uses tolerability to mean position-specific chemical modification compatibility/efficacy of siRNA variants, not biological toxicity, safety, or tolerability in cells, animals, or patients.",2026-06-07T02:20:35+00:00
31053,toxicity_endpoint,207,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,CS3D has low toxicity and modulation of immune parameters is associated with anti-tumor activity.,2026-06-07T02:20:35+00:00
31054,toxicity_endpoint,208,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Ten participants (approximately 7% of tofersen 100‐mg–treated trial participants) experienced a total of 12 serious neurologic AEs,2026-06-07T02:20:35+00:00
31055,toxicity_endpoint,209,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,All TEAEs were nonserious and mild or moderate in severity.,2026-06-07T02:20:35+00:00
31056,toxicity_endpoint,210,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Integrated safety analyses of participants receiving AT-DR (n = 286) demonstrated that AT-DR was well tolerated.,2026-06-07T02:20:35+00:00
31057,toxicity_endpoint,211,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39869489; Reject: METTL3/Smad3 work is renal allograft fibrosis mechanism biology; oligonucleotides are not a therapeutic product with measured safety/toxicity.,2026-06-07T02:20:35+00:00
31058,toxicity_endpoint,212,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Safety was confirmed via histopathological and ocular irritation assessments.,2026-06-07T02:20:35+00:00
31059,toxicity_endpoint,213,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 40616527; pmc_full_text evidence was direct but less than full primary-detail confidence for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31060,toxicity_endpoint,214,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,without causing significant immune or inflammatory responses. The minor intracranial hemorrhage resulting from this process was also shown to be recoverable.,2026-06-07T02:20:35+00:00
31061,toxicity_endpoint,215,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,there was no significant difference in the serum biochemical indices between the nanoparticles group and Control group,2026-06-07T02:20:35+00:00
31062,toxicity_endpoint,216,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"These polyplexes demonstrate suitable physicochemical properties, biocompatibility, and no adverse effects on neuronal electrophysiology.",2026-06-07T02:20:35+00:00
31063,toxicity_endpoint,217,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40156015; Reject: p53 siRNA is evaluated for therapeutic efficacy against AKI/cisplatin or ischemic injury; renal injury improvement is disease/toxin efficacy, not toxicity/safety of the oligo or delivery product.",2026-06-07T02:20:35+00:00
31064,toxicity_endpoint,218,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Laboratory assessments including complete blood count, serum chemistry, and protein levels in the CSF showed no abnormalities",2026-06-07T02:20:35+00:00
31065,toxicity_endpoint,219,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No lesions or pathological changes were observed in the heart, aortic roots, liver, spleen, lungs or kidneys.",2026-06-07T02:20:35+00:00
31066,toxicity_endpoint,220,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41445000; Reject: SRF/Cyr61 study uses siRNA as a mechanistic knockdown tool in renal injury progression; no therapeutic oligo safety/toxicity endpoint is measured.,2026-06-07T02:20:35+00:00
31067,toxicity_endpoint,221,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41382249; Reject: CD248 siRNA is a lab knockdown tool and the therapeutic agents are small molecules/natural products; renal injury/cell viability readouts are disease mechanism/efficacy, not oligo safety.",2026-06-07T02:20:35+00:00
31068,toxicity_endpoint,222,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38932395; Reject: the administered product is a therapeutic HPV DNA vaccine/LNP delivery comparison; siRNA appears only as background to approved LNP platforms, not as the measured therapeutic oligo.",2026-06-07T02:20:35+00:00
31069,toxicity_endpoint,223,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39548145; Reject: hepatotoxicity evidence concerns chemotherapy/tumor-EV injury and PPI effects; Trim21-ASOs are evaluated for delivery/anti-inflammatory efficacy in obesity rather than ASO toxicity or safety.,2026-06-07T02:20:35+00:00
31070,toxicity_endpoint,224,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In our study, 3.5% of the inclisiran ICSRs reported an ADR related to changes in liver function parameters",2026-06-07T02:20:35+00:00
31071,toxicity_endpoint,225,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38344840; Reject: RNA/DNA fiber NANPs are model immunorecognition scaffolds and THP1-Dual is a reporter cell line; the loaded passage does not establish a named therapeutic oligo/product with safety evidence.,2026-06-07T02:20:35+00:00
31072,toxicity_endpoint,226,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39049875; Reject: plasma aptamers are used as ex vivo profiling/prognostic reagents for COVID-19 mortality, not as administered therapeutic oligonucleotides with oligo-linked toxicity evidence.",2026-06-07T02:20:35+00:00
31073,toxicity_endpoint,227,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38684863; Reject: Asns-ASO findings are disease-efficacy/on-target PKD renal rescue readouts; the passage does not report oligo-linked toxicity or safety evidence.,2026-06-07T02:20:35+00:00
31074,toxicity_endpoint,228,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Adverse events were reported by two of eight, four of eight, and three of eight participants with mild, moderate, or severe HI, respectively; none were reported in the normal‐matched group.",2026-06-07T02:20:35+00:00
31075,toxicity_endpoint,229,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Treatment-emergent adverse events (TEAEs) and TEAEs at the injection site, mostly mild, were more frequent with inclisiran versus placebo (82.7% vs 70.7% and 3.6% vs 0%, respectively).",2026-06-07T02:20:35+00:00
31076,toxicity_endpoint,230,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"PS ASOs bind to platelet collagen receptor GPVI and directly activate minipig platelets in vitro, mirroring the findings in human blood samples.",2026-06-07T02:20:35+00:00
31077,toxicity_endpoint,231,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The most common lumasiran-related adverse events were mild, transient injection-site reactions (3 patients (17%)).",2026-06-07T02:20:35+00:00
31078,toxicity_endpoint,232,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37056835; Reject: ALKBH5/FTO GapmeR knockdown is a renal cancer cell biology/EMT assay, not a therapeutic oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31079,toxicity_endpoint,233,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37712257; Reject: the paper measures hepatic fat in ANGPTL3 loss-of-function participants/Mendelian analyses, not primary administered vupanorsen or other oligo safety outcomes.",2026-06-07T02:20:35+00:00
31080,toxicity_endpoint,234,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34085768; Reject: the passage is primarily PK/PD modeling and dose-FXI activity bridging; safety statements are background/context rather than a primary toxicity endpoint in this study.,2026-06-07T02:20:35+00:00
31081,toxicity_endpoint,235,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,We observed a significant decrease in platelet concentrations following incubation with 16 μM PS- or ME/PS-ASO and an even more significant decrease after platelets were exposed to a higher dose (24 μM) of oligonucleotide (Fig. 3A).,2026-06-07T02:20:35+00:00
31082,toxicity_endpoint,236,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35052426; Reject: complement-mediated aptamer tumor-cell lysis is intended anticancer cytotoxicity/efficacy, explicitly excluded from toxicity curation.",2026-06-07T02:20:35+00:00
31083,toxicity_endpoint,237,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The test showed that CS–ASO nanocomplexes did not have a significant effect on the viability of the cells, while Lipofectamine-containing systems displayed highly significant cytotoxicity (Figure 6).",2026-06-07T02:20:35+00:00
31084,toxicity_endpoint,238,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Modest effects on cell viability and mitochondrial DNA were observed in vitro in a subset of cell types at high concentrations of 2′-F-nucleosides, typically not attained in vivo.",2026-06-07T02:20:35+00:00
31085,toxicity_endpoint,239,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"A significant upregulation of immune system associated genes was observed in brains of AON treated mice, with the striatum showing largest transcriptional changes.",2026-06-07T02:20:35+00:00
31086,toxicity_endpoint,240,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,This analysis showed that there is no class generic effect on platelet numbers and no incidence of confirmed platelet levels below 50 K/μL in subjects treated with 2′MOE ASOs.,2026-06-07T02:20:35+00:00
31087,toxicity_endpoint,241,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"At high doses a number of toxicities were observed in nonhuman primates. However, no class safety effects were identified in healthy human volunteers from this integrated data analysis.",2026-06-07T02:20:35+00:00
31088,toxicity_endpoint,242,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,DHA-hsiRNAs do not induce neural cell death or measurable innate immune activation following administration of concentrations over 20 times above the efficacious dose.,2026-06-07T02:20:35+00:00
31089,toxicity_endpoint,243,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Dose-dependent hepatic changes associated with hepatocyte necrosis and increases in serum alanine-aminotransferase levels have been observed after treatment with certain oligonucleotides.,2026-06-07T02:20:35+00:00
31090,toxicity_endpoint,244,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No new safety signals were identified.,2026-06-07T02:20:35+00:00
31091,toxicity_endpoint,245,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Significant ATP depletion was observed only after prolonged exposure to SPC5001, a nephrotoxic antisense oligonucleotide.",2026-06-07T02:20:35+00:00
31092,toxicity_endpoint,246,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Acute and subacute toxicity studies revealed no systemic toxicity at the highest nonlethal dose (32 mg/kg).,2026-06-07T02:20:35+00:00
31093,toxicity_endpoint,247,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No new safety effects were identified.,2026-06-07T02:20:35+00:00
31094,toxicity_endpoint,248,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The proportion of participants with at least one adverse event during the double-blind treatment period was 54 (69%) of 78 in the cemdisiran group, 65 (81%) of 80 in the combination group, 40 (82%) of 49 in the pozelimab group, and 54 (77%) of 70 in the placebo group.",2026-06-07T02:20:35+00:00
31095,toxicity_endpoint,249,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No cytotoxicity was observed.,2026-06-07T02:20:35+00:00
31096,toxicity_endpoint,250,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Among 4685 adverse event reports of inclisiran, 523 MAEs reports were found.",2026-06-07T02:20:35+00:00
31097,toxicity_endpoint,251,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,inclisiran demonstrated strong hepatic toxicity signals,2026-06-07T02:20:35+00:00
31098,toxicity_endpoint,252,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41879506; Opinion article on adversity interpretation for intrathecal oligonucleotides; no primary administered/measured toxicity result for a specific oligonucleotide product.,2026-06-07T02:20:35+00:00
31099,toxicity_endpoint,253,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,RGLS4326 was generally well tolerated,2026-06-07T02:20:35+00:00
31100,toxicity_endpoint,254,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 41956189; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31101,toxicity_endpoint,255,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41500345; Passage describes delivery efficiency and receptor-mediated gene regulation but provides no primary measured toxicity or safety endpoint.,2026-06-07T02:20:35+00:00
31102,toxicity_endpoint,256,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41654146; Resveratrol protection against colistin nephrotoxicity is a natural-product/small-molecule injury model; Nrf2 siRNA is only a mechanistic lab knockdown tool.,2026-06-07T02:20:35+00:00
31103,toxicity_endpoint,257,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42069296; GSTK1/OSBPL8 siRNAs are in vitro mechanistic knockdown tools in diabetic nephropathy biology, not therapeutic oligonucleotide toxicity evidence.",2026-06-07T02:20:35+00:00
31104,toxicity_endpoint,258,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,both formulations were nonhemolytic across all concentrations,2026-06-07T02:20:35+00:00
31105,toxicity_endpoint,259,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,without detectable hemolysis or cytotoxicity,2026-06-07T02:20:35+00:00
31106,toxicity_endpoint,260,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 41076799; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31107,toxicity_endpoint,261,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42203164; Trial design abstract for an ongoing inclisiran study; safety monitoring is planned, but no observed/administered toxicity result is reported.",2026-06-07T02:20:35+00:00
31108,toxicity_endpoint,262,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 42007960; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31109,toxicity_endpoint,263,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 41783937; previous accept was too weak/generic for hepatic/hepatotoxicity in CT26. Basis checked: Abstract gives a primary but generic biocompatibility result for siAURKB-loaded nanomedicine; safety endpoint is weakly specified.,2026-06-07T02:20:35+00:00
31110,toxicity_endpoint,264,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Nusinersen-induced adverse events were observed,2026-06-07T02:20:35+00:00
31111,toxicity_endpoint,265,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,ASO toxicity is strongly influenced,2026-06-07T02:20:35+00:00
31112,toxicity_endpoint,266,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,liver enzyme and histopathology changes,2026-06-07T02:20:35+00:00
31113,toxicity_endpoint,267,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Accept C as borderline: PMID 41457341; curator counted hepatic/hepatotoxicity for unspecified siRNA despite v2 exclusion. Low-confidence override; v2 note was: Proceedings/seminar summary mentions a siRNA hepatotoxicity case but is not a primary toxicity study with sufficient product-level grounding.,2026-06-07T02:20:35+00:00
31114,toxicity_endpoint,268,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,significantly reduce hepatotoxicity in mice,2026-06-07T02:20:35+00:00
31115,toxicity_endpoint,269,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39569667; Study evaluates sulfonamide-linked LNA gapmer duplex stability and RNase H activity; toxicity is background motivation, not a measured endpoint.",2026-06-07T02:20:35+00:00
31116,toxicity_endpoint,270,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,SPL84 was safe and well-tolerated,2026-06-07T02:20:35+00:00
31117,toxicity_endpoint,271,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,no significant cytotoxicity or liver toxicity in mice,2026-06-07T02:20:35+00:00
31118,toxicity_endpoint,272,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41065179; Reported cytotoxicity is NK-cell-mediated tumor-killing efficacy, explicitly excluded as cancer-cell-killing cytotoxicity rather than safety toxicity.",2026-06-07T02:20:35+00:00
31119,toxicity_endpoint,273,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,not associated with any toxicity-related morbidity or mortality,2026-06-07T02:20:35+00:00
31120,toxicity_endpoint,274,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40990894; Valproic-acid hepatotoxicity is a small-molecule injury model; ACSL4 siRNA is only an in vitro mechanistic knockdown tool.,2026-06-07T02:20:35+00:00
31121,toxicity_endpoint,275,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39488022; Abstract states that cytotoxicity and oxidative-stress assays were performed but gives no observed safety/toxicity result to curate.,2026-06-07T02:20:35+00:00
31122,toxicity_endpoint,276,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41277575; Abstract reports delivery-vector cytotoxicity in a GFP knockdown proof-of-concept, but no named therapeutic oligonucleotide or disease-targeted administered oligo; excluded as lab knockdown/delivery tool.",2026-06-07T02:20:35+00:00
31123,toxicity_endpoint,277,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41165149; The cytotoxicity statement is multimodal cancer-cell killing efficacy after PD-L1 siRNA/doxorubicin/ICG treatment, not safety or tolerability evidence.",2026-06-07T02:20:35+00:00
31124,toxicity_endpoint,278,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Cell viability assay revealed that LP5-SeNP and the LP5-SeNP/siRNA complex did not exhibit any cytotoxicity at their experimental concentration.,2026-06-07T02:20:35+00:00
31125,toxicity_endpoint,279,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40939253; Low-toxicity language is linked to a generic CPP/siRNA delivery strategy without a named therapeutic oligo or disease-targeted administered oligo; excluded as unclear/lab delivery evidence.,2026-06-07T02:20:35+00:00
31126,toxicity_endpoint,280,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40877516; Methods/chapter abstract describes construction and evaluation metrics for bioinspired nanovesicles, with no primary observed toxicity or safety result for an administered siRNA product.",2026-06-07T02:20:35+00:00
31127,toxicity_endpoint,281,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40816350; Reported cytotoxicity is formulation killing of colon cancer cells for chemotherapy/RNAi efficacy; no separable safety/tolerability endpoint for the oligo or delivery product is grounded.,2026-06-07T02:20:35+00:00
31128,toxicity_endpoint,282,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40812552; Abstract claims reduced toxicity in a therapeutic narrative but does not provide a primary measured toxicity/safety endpoint linked to siTNFalpha or its polymersome product.,2026-06-07T02:20:35+00:00
31129,toxicity_endpoint,283,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Experiments with BEAS-2B and H460 cells showed that TUBB3/DTX-LNPs had low cytotoxicity and good biocompatibility with BEAS-2B but strongly inhibited H460 cells.,2026-06-07T02:20:35+00:00
31130,toxicity_endpoint,284,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40576767; The siRNA cargo is siRNA-FAM for gene-transfer assessment and the cytotoxicity is in MCF-7 cancer cells; this is not a therapeutic oligonucleotide safety endpoint.,2026-06-07T02:20:35+00:00
31131,toxicity_endpoint,285,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40328700; Cytotoxicity reduction is reported for CS/HA nanoparticles used with luciferase siRNA in HeLa-Luc cells, which is a lab reporter knockdown tool rather than a therapeutic oligo safety result.",2026-06-07T02:20:35+00:00
31132,toxicity_endpoint,286,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40267508; Machine-learning/QSAR paper predicts activity and cell viability from curated LNP datasets; it is not a primary administered/measured toxicity result for a specific oligo product.,2026-06-07T02:20:35+00:00
31133,toxicity_endpoint,287,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40237047; Review-style abstract discusses chemotherapy toxicity and potential reduced toxicity with siRNA combinations, but provides no primary observed safety/tolerability result.",2026-06-07T02:20:35+00:00
31134,toxicity_endpoint,288,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The PEGylated DIPEA-chitosan/siRNA polyplexes demonstrated positive zeta potentials (up to + 11 mV), particle sizes of 100-200 nm, and very low cytotoxicity in keratinocyte and fibroblast cell lines.",2026-06-07T02:20:35+00:00
31135,toxicity_endpoint,289,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39705128; Abstract mentions high-toxicity bolus injection as background but reports release, syringeability, and clearance; no primary toxicity/safety endpoint is measured.",2026-06-07T02:20:35+00:00
31136,toxicity_endpoint,290,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 40306578; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31137,toxicity_endpoint,291,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 40073943; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31138,toxicity_endpoint,292,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40043915; Carrier toxicity appears only as a general translational limitation; the abstract reports efficacy of FTBR-NAC/siBACE1 but no measured toxicity or safety endpoint.,2026-06-07T02:20:35+00:00
31139,toxicity_endpoint,293,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The risk of adverse events was similar across groups; the most common adverse events were abdominal pain, nasopharyngitis, headache, and nausea.",2026-06-07T02:20:35+00:00
31140,toxicity_endpoint,294,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40409597; Oligonucleotide DAMP fraction is an endogenous disease-associated cytotoxic fraction in post-COVID surgical pathology, not an administered therapeutic oligonucleotide.",2026-06-07T02:20:35+00:00
31141,toxicity_endpoint,295,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39637936; WSSV dsRNA in freshwater crayfish/aquaculture immune stimulation is outside therapeutic oligonucleotide scope and falls under agricultural/invertebrate RNAi exclusion.,2026-06-07T02:20:35+00:00
31142,toxicity_endpoint,296,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"However, there was a significant increase in mean alanine transaminase levels compared with placebo in the upper dose range of the unconjugated 2'MOE ASO group.",2026-06-07T02:20:35+00:00
31143,toxicity_endpoint,297,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Weekly intra-abdominal administration of ASO-4733 (125 mg/kg), corresponding to a 50-fold increase of the estimated clinical dose for 4 weeks, was well tolerated by cynomolgus monkeys.",2026-06-07T02:20:35+00:00
31144,toxicity_endpoint,298,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,All participants had at least one adverse event; most adverse events were mild or moderate in severity and did not lead to treatment discontinuation.,2026-06-07T02:20:35+00:00
31145,toxicity_endpoint,299,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 38394820; previous accept was too weak/generic for hepatic/hepatotoxicity in CCA12; ETD12. Basis checked: Abstract reports primary cytotoxicity testing of cationic cubosome delivery particles relevant to oligonucleotide delivery, but evidence is generic and not tied to a loaded therapeutic olig?",2026-06-07T02:20:35+00:00
31146,toxicity_endpoint,300,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The BPP-PMO conjugates significantly increased the level of full-length SMN2 in the patient-derived SMA fibroblasts in a concentration-dependent manner with minimal to no toxicity.,2026-06-07T02:20:35+00:00
31147,toxicity_endpoint,301,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The optimized formulations appeared to be safe on ex vivo fetal lungs as indicated by insignificant changes in apoptosis (Caspase-3) and proliferation (Ki67) markers.,2026-06-07T02:20:35+00:00
31148,toxicity_endpoint,302,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38341177; Reject: passage mainly reports PLK1 silencing and anti-neuroblastoma efficacy; low-toxicity language describes the delivery approach generally and gives no primary measured safety endpoint.,2026-06-07T02:20:35+00:00
31149,toxicity_endpoint,303,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Safety of DSPE-PNMVA24 is confirmed at the cellular level and in animal models of zebrafish and mice.,2026-06-07T02:20:35+00:00
31150,toxicity_endpoint,304,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,AEs occurred in 35.9% of patients (49.0% in infantile-onset SMA and 30.6% in later-onset SMA).,2026-06-07T02:20:35+00:00
31151,toxicity_endpoint,305,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The incidence proportion of AEs was 31.7% (37.3% in infantile-onset SMA and 29.1% in later-onset SMA).,2026-06-07T02:20:35+00:00
31152,toxicity_endpoint,306,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39388218; Reject: passage reports AR-V7 siRNA chimera knockdown and prostate cancer xenograft efficacy; the low-toxicity statement is not a grounded primary safety result.,2026-06-07T02:20:35+00:00
31153,toxicity_endpoint,307,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 38692174; previous accept was too weak/generic for hepatic/hepatotoxicity in MCT4. Basis checked: Abstract primarily reports cancer efficacy, but gives weak comparative safety evidence indicating minimal effect in a normal cell line for the siRNA LNP treatment.",2026-06-07T02:20:35+00:00
31154,toxicity_endpoint,308,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Cop+-FND : siRNA potently inhibited the target GAPDH gene with negligible toxicity and sufficient colloidal stability.,2026-06-07T02:20:35+00:00
31155,toxicity_endpoint,309,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Developed LCAr showed ~4 times less hemolytic potential as compared to the parent polyplexes at the highest siRNA dose.,2026-06-07T02:20:35+00:00
31156,toxicity_endpoint,310,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39514216; Reject: passage contains only broad safe-vector language and gene-delivery efficacy, without a primary measured toxicity or tolerability endpoint.",2026-06-07T02:20:35+00:00
31157,toxicity_endpoint,311,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In vivo data confirmed that the dual gene delivery system successfully targeted CT-26 tumors in tumor-bearing BALB/c mice, and exhibited strong tumor suppression ability, without inducing adverse toxic effects.",2026-06-07T02:20:35+00:00
31158,toxicity_endpoint,312,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38614225; Reject: siRNA is used as a lab knockdown tool to study endogenous LY96 biology in a Parkinson disease cell model; viability changes are not oligo safety evidence.,2026-06-07T02:20:35+00:00
31159,toxicity_endpoint,313,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Having optimized the GalNAc-engineering strategy, insertion orders, and cell membrane source, we obtained the best-performing GalNAc-formulations allowing strong hepatocyte-specific internalization with reduced Kupffer cell capture, resulting in robust gene silencing and less hepatotoxicity when compared with cationic lipid-based GalNAc-formulations.",2026-06-07T02:20:35+00:00
31160,toxicity_endpoint,314,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39366156; Reject: study concerns Artemisia argyi essential oil protection from acetaminophen hepatotoxicity; CYP2E1 siRNA is only a mechanistic lab knockdown tool.,2026-06-07T02:20:35+00:00
31161,toxicity_endpoint,315,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The nanoparticles exhibit no cytotoxicity and can bind to both plasmid DNA (pDNA) as well as small interference RNA (siRNA).,2026-06-07T02:20:35+00:00
31162,toxicity_endpoint,316,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Combining the adjuvanticity of aluminum and CpG with RNA interference and MPN coating results in a nanoadjuvant that exhibits greater accumulation in lymph nodes and elicits improved maturation of dendritic cells in comparison to a formulation without siRNA or MPN, and with no observable organ toxicity.",2026-06-07T02:20:35+00:00
31163,toxicity_endpoint,317,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38898204; Reject: 5TR1 aptamer is a targeting ligand for silybin nanoparticle delivery, and cancer-cell cytotoxicity is anti-cancer efficacy rather than therapeutic oligo toxicity.",2026-06-07T02:20:35+00:00
31164,toxicity_endpoint,318,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"All 15 participants completed the study. Eteplirsen was well tolerated with no treatment-related discontinuations, deaths or evidence of kidney toxicity.",2026-06-07T02:20:35+00:00
31165,toxicity_endpoint,319,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,siApoB-Loaded BCP (BCP-siApoB) outperformed lipofectamine counterparts and silenced 93% of ApoB mRNA in HepG2 cells at 50 nM siApoB without inducing cytotoxicity.,2026-06-07T02:20:35+00:00
31166,toxicity_endpoint,320,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"All treatment-emergent adverse events (AEs) were mild and resolved by study end, and no AEs or serious AEs resulted in premature study discontinuation or death.",2026-06-07T02:20:35+00:00
31167,toxicity_endpoint,321,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Safety findings demonstrated a continued positive risk/benefit profile for givosiran.,2026-06-07T02:20:35+00:00
31168,toxicity_endpoint,322,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 37437196; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31169,toxicity_endpoint,323,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The most frequent treatment-emergent adverse event in the fitusiran prophylaxis group was increased alanine aminotransferase in 13 (32%) of 41 participants in the safety population; there were no increased alanine aminotransferase treatment-emergent adverse events in the bypassing agents on-demand group.,2026-06-07T02:20:35+00:00
31170,toxicity_endpoint,324,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No adverse effects of any of the vaccine formulations were observed in the immunized dams or their pups.,2026-06-07T02:20:35+00:00
31171,toxicity_endpoint,325,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No serious adverse events or clinically relevant abnormalities in any laboratory parameters were noted.,2026-06-07T02:20:35+00:00
31172,toxicity_endpoint,326,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36541426; Reject: passage reports cytotoxicity/biocompatibility of generic PEI nanoparticles in a tumor tissue-slice delivery test system, but no named therapeutic oligonucleotide or therapeutic delivery product safety result is grounded.",2026-06-07T02:20:35+00:00
31173,toxicity_endpoint,327,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We report here on the development of a siRNA-loaded lipid nanoparticle (LNP) composed of CL1H6 (CL1H6-LNP), an optimized, pH-sensitive cationic lipid, with efficient gene silencing and low cytotoxicity in NK-92 cells.",2026-06-07T02:20:35+00:00
31174,toxicity_endpoint,328,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,This study reveals different patterns of cell death associated with toxicity in liver (apoptosis and necrosis) and kidney (necrosis only),2026-06-07T02:20:35+00:00
31175,toxicity_endpoint,329,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Suprapharmacologic doses of ISIS 702843 were well tolerated in NHPs after chronic dosing, and the data indicate that the overall safety profile is very similar to that of the unconjugated 2'-(2-methoxyethyl)-D-ribose (2'-MOE) ASOs.",2026-06-07T02:20:35+00:00
31176,toxicity_endpoint,330,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The most common adverse events were related to tolerability and included injection-site reactions,2026-06-07T02:20:35+00:00
31177,toxicity_endpoint,331,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 34437914; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31178,toxicity_endpoint,332,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34297902; Reject: passage reports PNPLA3 allele-specific siRNA discovery, knockdown, and NASH disease-phenotype prevention; the only safety statement is an unknown concern, not a measured oligo toxicity endpoint.",2026-06-07T02:20:35+00:00
31179,toxicity_endpoint,333,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Dosing 50 mg/kg of the tool ASO resulted in mild proximal tubular pathology and elevations in KIM-1, clusterin, NGAL, and cystatin C.",2026-06-07T02:20:35+00:00
31180,toxicity_endpoint,334,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Finally, no association was observed between IM and toxicity findings (eg, platelet, complement activation, and histopathology findings) in the inotersen 9-month monkey study.",2026-06-07T02:20:35+00:00
31181,toxicity_endpoint,335,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"There was a lack of discernable toxicity, mortality and systemic inflammatory or immunological responses in mice following administration of either MNVs or tMNVs.",2026-06-07T02:20:35+00:00
31182,toxicity_endpoint,336,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32907491; Reject: cytotoxicity is reported for a virus-like protein carrier in T. cruzi AON transfection/biological-study development, not a therapeutic oligonucleotide safety result in scope.",2026-06-07T02:20:35+00:00
31183,toxicity_endpoint,337,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32529417; Reject: itraconazole/pDNA/Bcl2 siRNA passage focuses on delivery enhancement and cholesterol trafficking; it gives no grounded primary toxicity result for an in-scope oligo product.,2026-06-07T02:20:35+00:00
31184,toxicity_endpoint,338,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The results show that these 2'-MOE ASOs selected for development have consistent behavior between sequences, have tolerability profiles suitable for chronic administration",2026-06-07T02:20:35+00:00
31185,toxicity_endpoint,339,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 30095329; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31186,toxicity_endpoint,340,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29360004; Reject: passage measures renal distribution/pharmacokinetic redirection of ASOs and only infers nephrotoxic potential; PK/biodistribution without measured toxicity is excluded.,2026-06-07T02:20:35+00:00
31187,toxicity_endpoint,341,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,which resulted in a substantial improvement of hepatocyte-specificity and in a dramatic reduction in toxicity.,2026-06-07T02:20:35+00:00
31188,toxicity_endpoint,342,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"ss PS-ONs were more cytotoxic than double-stranded (ds) PS-ONs, irrespective of the 2'-ribose chemistry, inclusive of the 2'-F modification.",2026-06-07T02:20:35+00:00
31189,toxicity_endpoint,343,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,None of the experiments demonstrated a genotoxic effect for the five tested LNA-ONs.,2026-06-07T02:20:35+00:00
31190,toxicity_endpoint,344,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,There was no sign of cytotoxicity or immune response caused by KL4 and KL4/siRNA complexes.,2026-06-07T02:20:35+00:00
31191,toxicity_endpoint,345,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Findings in these studies were limited to the kidneys, with a common presentation of tubular basophilia, vacuolation, and/or minimal degeneration that was considered non-adverse.",2026-06-07T02:20:35+00:00
31192,toxicity_endpoint,346,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"After repeated administration, a toxic LNA gapmer (TS-2), but not a non-toxic LNA gapmer (NTS-1), caused hepatocyte necrosis and increased serum alanine aminotransferase levels.",2026-06-07T02:20:35+00:00
31193,toxicity_endpoint,347,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The most common adverse events in drisapersen-treated patients were injection-site reactions (14 patients given continuous drisapersen, 15 patients given intermittent drisapersen, and six given placebo) and renal events (13 for continuous drisapersen, 12 for intermittent drisapersen, and seven for placebo), most of which were subclinical proteinuria.",2026-06-07T02:20:35+00:00
31194,toxicity_endpoint,348,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Systemic bioavailability was minimal, and no systemic toxicity was observed at exposure levels appreciably above pharmacological doses and doses proposed for clinical trials.",2026-06-07T02:20:35+00:00
31195,toxicity_endpoint,349,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 23308382; Reject: passage concerns neutralization of pathogenic mutant RNA toxicity and disease efficacy in myotonic dystrophy, not toxicity or safety of the administered PPMO oligonucleotide.",2026-06-07T02:20:35+00:00
31196,toxicity_endpoint,350,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Minimal to slight proximal tubular epithelial cell degeneration and regeneration within the kidney was observed, which had no impact on renal function and showed reversibility at the end of the treatment-free period.",2026-06-07T02:20:35+00:00
31197,toxicity_endpoint,351,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 21982682; CpG-DNA is used as a vaccine adjuvant and the reported cytotoxicity/cytokine readouts are immunotherapy efficacy or immune activation, not primary safety/toxicity/tolerability evidence linked to the oligo.",2026-06-07T02:20:35+00:00
31198,toxicity_endpoint,352,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,followed by acute transaminitis and extensive hepatocyte apoptosis and necrosis at 72 h,2026-06-07T02:20:35+00:00
31199,toxicity_endpoint,353,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"with no effects on PT, platelets, or increased bleeding following partial tail amputation or gum and skin laceration",2026-06-07T02:20:35+00:00
31200,toxicity_endpoint,354,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In monkeys, there was a dose-related increase in GTI-2040 plasma levels with concomitant increase in complement activation and prolongation of activated partial thromboplastin time.",2026-06-07T02:20:35+00:00
31201,toxicity_endpoint,355,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Drug-related microscopic renal effects were dose-dependent, apparently reversible",2026-06-07T02:20:35+00:00
31202,toxicity_endpoint,356,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Both AVI-4658 and AVI-4225 were well-tolerated at all doses.,2026-06-07T02:20:35+00:00
31203,toxicity_endpoint,357,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41863245; Review article about ASO stability, safety concerns, and adverse effects; no primary observed/administered/measured toxicity result for a specific therapeutic oligo product.",2026-06-07T02:20:35+00:00
31204,toxicity_endpoint,358,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No serious adverse events, deaths or discontinuations occurred.",2026-06-07T02:20:35+00:00
31205,toxicity_endpoint,359,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Inclisiran was well tolerated, with a safety profile comparable to studies in adults.",2026-06-07T02:20:35+00:00
31206,toxicity_endpoint,360,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 42198843; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31207,toxicity_endpoint,361,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,All therapies were well-tolerated with no new safety signals.,2026-06-07T02:20:35+00:00
31208,toxicity_endpoint,362,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No adverse effects on either the liver or kidney function were observed.,2026-06-07T02:20:35+00:00
31209,toxicity_endpoint,363,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Adverse effects (5.8%) were mild.,2026-06-07T02:20:35+00:00
31210,toxicity_endpoint,364,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"generally well tolerated, with no adverse effects on body weight or pulmonary function at therapeutic doses",2026-06-07T02:20:35+00:00
31211,toxicity_endpoint,365,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Transient and reversible alanine amino transferase elevations (3-5X fold upper limit normal) without a change in bilirubin were observed in three individuals,2026-06-07T02:20:35+00:00
31212,toxicity_endpoint,366,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42138142; Main platform centers lung-targeted LNP delivery of mRNA/gene-editing cargos, including ABE mRNA and sgRNA, which falls under mRNA/CRISPR-style scope exclusions; safety is not specifically grounded to an administered therapeutic siRNA product.",2026-06-07T02:20:35+00:00
31213,toxicity_endpoint,367,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 42126331; previous accept was too weak/generic for hepatic/hepatotoxicity in Cy3; HEK293. Basis checked: Primary abstract reports an siRNA nanogel delivery platform with preliminary in vitro cellular safety/compatibility evidence, but the safety endpoint is generic and weak.",2026-06-07T02:20:35+00:00
31214,toxicity_endpoint,368,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Both in vitro and in vivo studies indicated a favorable safety profile for DAS-LNP.,2026-06-07T02:20:35+00:00
31215,toxicity_endpoint,369,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"induced minimal hemoglobin release, with hemolysis rates remaining below safety threshold.",2026-06-07T02:20:35+00:00
31216,toxicity_endpoint,370,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No events of retinal vasculitis, ischemic optic neuropathy, or serious intraocular inflammation occurred over 2 years.",2026-06-07T02:20:35+00:00
31217,toxicity_endpoint,371,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,There were no deaths or serious AEs,2026-06-07T02:20:35+00:00
31218,toxicity_endpoint,372,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Three participants reported five mild adverse events, none of which were considered related to nusinersen by the investigators.",2026-06-07T02:20:35+00:00
31219,toxicity_endpoint,373,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject after curator re-read: PMID 42069271; previous accept was too weak/generic for hepatic/hepatotoxicity in EC50; HEK293; SY5Y. Basis checked: Primary abstract reports PLGA nanoparticle platform incorporating an ASO with in vitro biocompatibility evidence, but the safety endpoint is cell-culture-level and generic.",2026-06-07T02:20:35+00:00
31220,toxicity_endpoint,374,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 41691403; previous accept was too weak/generic for hepatic/hepatotoxicity in unspecified siRNA. Basis checked: Primary abstract reports RNA delivery materials spanning RNA therapeutics including siRNA and notes no acute adverse phenotypic effects; safety evidence is generic and not siRNA-specific.,2026-06-07T02:20:35+00:00
31221,toxicity_endpoint,375,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41655906; siRNA cancer immunotherapy nanoplatform passage reports tumor immune activation, PD-L1/Carm1 knockdown, and tumor growth efficacy; it provides no primary toxicity/safety/tolerability endpoint for the oligo product.",2026-06-07T02:20:35+00:00
31222,toxicity_endpoint,376,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Elevations in liver-enzyme levels and thrombocytopenia (platelet count, <100,000 per microliter) were more common with the 80-mg dose of olezarsen, and a dose-dependent increase in the hepatic fat fraction was noted.",2026-06-07T02:20:35+00:00
31223,toxicity_endpoint,377,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"this combination therapy is well-tolerated in non-human primates, with no observable changes in physical condition or behavior, blood parameters, or organ histology.",2026-06-07T02:20:35+00:00
31224,toxicity_endpoint,378,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Two patients showed significant treatment-related adverse events, namely swelling of the dorsal surface of the right hand due to extravasation of viltolarsen in one patient and axillary lymph node enlargement due to frequent intravenous infusion in another patient.",2026-06-07T02:20:35+00:00
31225,toxicity_endpoint,379,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,a single dose of HT-101 at 25-800 mg was safe and well tolerated in healthy Chinese volunteers.,2026-06-07T02:20:35+00:00
31226,toxicity_endpoint,380,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 41121471; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31227,toxicity_endpoint,381,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40436308; Design/rationale abstract describes planned assessment of inclisiran safety and quality-of-life outcomes but provides no primary observed/administered/measured toxicity or safety result.,2026-06-07T02:20:35+00:00
31228,toxicity_endpoint,382,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Inclisiran was well tolerated, with no new safety concerns.",2026-06-07T02:20:35+00:00
31229,toxicity_endpoint,383,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Furthermore, R-LNPs demonstrated favorable safety in in vivo application.",2026-06-07T02:20:35+00:00
31230,toxicity_endpoint,384,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 40242982; weak/generic or abstract-limited support for general safety/safety/tolerability.,2026-06-07T02:20:35+00:00
31231,toxicity_endpoint,385,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Moreover, they exhibit enhanced resistance to vibrating mesh nebulization and reduced inflammatory activation of bronchial epithelial cells.",2026-06-07T02:20:35+00:00
31232,toxicity_endpoint,386,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No severe adverse events were observed.,2026-06-07T02:20:35+00:00
31233,toxicity_endpoint,387,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40928959; Scope exclusion: the intervention is a TCM-derived small molecule/natural product and ultrasound delivery, while CXCL5 siRNA is used as a mechanistic knockdown tool; toxicity/safety evidence is not linked to a therapeutic oligonucleotide product.",2026-06-07T02:20:35+00:00
31234,toxicity_endpoint,388,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No adverse effects were recorded within histological assessments on the liver, kidney, and heart post-treatment.",2026-06-07T02:20:35+00:00
31235,toxicity_endpoint,389,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Adverse events were mild. Moderate HI did not have a clinically relevant impact on bepirovirsen PK or safety.,2026-06-07T02:20:35+00:00
31236,toxicity_endpoint,390,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The most common adverse events were erythema at the injection site, headache, and nasopharyngitis; 98% of adverse events were mild or moderate in severity.",2026-06-07T02:20:35+00:00
31237,toxicity_endpoint,391,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 38636882; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31238,toxicity_endpoint,392,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C as borderline: PMID 38269451; curator counted general safety/safety/tolerability for CDR132L despite v2 exclusion. Low-confidence override; v2 note was: Trial rationale/design abstract for CDR132L describes planned efficacy and safety assessment and cites prior phase 1b tolerability, but does not report a primary observe?",2026-06-07T02:20:35+00:00
31239,toxicity_endpoint,393,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 39146787; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31240,toxicity_endpoint,394,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Most treatment emergent adverse events were grades 1-2. Three (20%) participants in cohort 1, four (27%) in cohort 2, eight (44%) in cohort 3, seven (39%) in cohort 4, six (46%) in cohort 5, and two (40%) in cohort 6 reported treatment-emergent adverse events related to VIR-2218.",2026-06-07T02:20:35+00:00
31241,toxicity_endpoint,395,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38925238; Scope exclusion: the therapeutic payload is the small-molecule chemotherapy SN38 and AS1411 is a targeting aptamer on the carrier; the reported cancer-cell toxicity is an antitumor efficacy readout, not oligonucleotide safety evidence.",2026-06-07T02:20:35+00:00
31242,toxicity_endpoint,396,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In a rat toxicology study, TNA placed at position 7 of the antisense strand of the siRNA mitigated off-target effects, likely due to the decrease in the thermodynamic binding affinity relative to the 2'-O-methyl residue.",2026-06-07T02:20:35+00:00
31243,toxicity_endpoint,397,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,An increase in the number of large particle-size events with platelet activation was detected in the Chol-ASO-treated group.,2026-06-07T02:20:35+00:00
31244,toxicity_endpoint,398,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Kaplan-Meier analyses showed that TEAEs that were serious or led to discontinuation; hepatic, muscle, and kidney events; incident diabetes; and elevations of creatine kinase or creatinine accrued at a comparable rate between groups for up to 1.5 years, with similar trends continuing for inclisiran beyond this period.",2026-06-07T02:20:35+00:00
31245,toxicity_endpoint,399,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Ten (2%) of 470 patients had serious adverse events during the treatment phase, and two patients (one each from the JNJ-3989 dual 200 mg group [exercise-related rhabdomyolysis] and the triple group [increase in ALT or AST]) had serious adverse events related to study treatment.",2026-06-07T02:20:35+00:00
31246,toxicity_endpoint,400,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Common adverse events were injection site reactions and platelet count decrease, consistent with previous studies.",2026-06-07T02:20:35+00:00
31247,toxicity_endpoint,401,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Adverse events at the injection site were reported in 39 (14%) of 284 patients in the inclisiran-only arm and 12 (14%) of 87 patients in the switching arm.,2026-06-07T02:20:35+00:00
31248,toxicity_endpoint,402,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"There were no preclinical safety findings with SPL84; no related clinical signs, nor any effect on body weight, food consumption, or clinical pathology.",2026-06-07T02:20:35+00:00
31249,toxicity_endpoint,403,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35073217; Reject under v2: Malat1 gapmer is a non-therapeutic endogenous lncRNA knockdown/chemistry model; safety signals are not tied to a therapeutic oligonucleotide candidate.,2026-06-07T02:20:35+00:00
31250,toxicity_endpoint,404,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35762447; Reject under v2: review/expert-opinion passage summarizes thrombocytopenia risk for APOC3 therapies but does not provide primary observed/administered toxicity data.,2026-06-07T02:20:35+00:00
31251,toxicity_endpoint,405,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33443084; Reject under v2: passage reports therapeutic efficacy and improvement of nephrotic-syndrome renal injury, not toxicity/safety/tolerability of the ANGPTL3 siRNA product.",2026-06-07T02:20:35+00:00
31252,toxicity_endpoint,406,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33439616; Reject under v2: EGFP-siRNA is a reporter/lab knockdown tool; although lung biocompatibility was measured for the delivery system, the oligo is not a therapeutic candidate.",2026-06-07T02:20:35+00:00
31253,toxicity_endpoint,407,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The expected common class effects were observed at the 30 mg/kg/week dose level in hematology, serum chemistry, and histopathology.",2026-06-07T02:20:35+00:00
31254,toxicity_endpoint,408,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In response to continued dosing, PLT counts were decreased by 50%-90% by day 30 in all monkeys.",2026-06-07T02:20:35+00:00
31255,toxicity_endpoint,409,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 29753959; previous accept was too weak/generic for hepatic/hepatotoxicity in unspecified antisense oligonucleotide. Basis checked: Abstract gives weak but direct in vivo safety/tolerability evidence for ASO delivery after angubindin-1 BBB modulation.,2026-06-07T02:20:35+00:00
31256,toxicity_endpoint,410,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No changes in kidney function were observed.,2026-06-07T02:20:35+00:00
31257,toxicity_endpoint,411,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Rates of adverse events were similar in the two groups after the HBV-ISS injections regardless of the schedule, but more frequent than after the placebo injections.",2026-06-07T02:20:35+00:00
31258,toxicity_endpoint,412,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Both vaccines were welltolerated although injection-site reactions were reported at a higher rate in HBV-ISS recipients.,2026-06-07T02:20:35+00:00
31259,toxicity_endpoint,413,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"However, there were no renal functional abnormalities as determined by the typical measurements of blood urea nitrogen, serum creatinine, creatinine clearance, or urine specific gravity.",2026-06-07T02:20:35+00:00
31260,toxicity_endpoint,414,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No serious adverse events, treatment discontinuations because of adverse events, or deaths occurred.",2026-06-07T02:20:35+00:00
31261,toxicity_endpoint,415,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Body weight was comparable between the mouse groups over the 4 w treatment period (Figure S13A).,2026-06-07T02:20:35+00:00
31262,toxicity_endpoint,416,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Notably, AEs related to renal function abnormalities, such as abnormal Urine protein/creatinine ratio and protein urine presence, showed higher frequency and signal strength.",2026-06-07T02:20:35+00:00
31263,toxicity_endpoint,417,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Proportions of patients with reported treatment-emergent adverse events (TEAEs) and treatment-emergent serious adverse events were similar between treatment arms, irrespective of PVD status, except for an excess of mild or moderate clinically relevant TEAEs at the injection site with inclisiran.",2026-06-07T02:20:35+00:00
31264,toxicity_endpoint,418,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The safety of the two combinations and the PK of the four components were similar, regardless of the target RNA sequence.",2026-06-07T02:20:35+00:00
31265,toxicity_endpoint,419,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Across species, inhibition-like responses peaked ∼3 h post-ASO delivery, reversed within 24 h with no sequelae, and could be quantified using simple neurobehavioral scales.",2026-06-07T02:20:35+00:00
31266,toxicity_endpoint,420,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The no observed adverse effect level was established at 300 mg/kg.,2026-06-07T02:20:35+00:00
31267,toxicity_endpoint,421,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In vitro experiments demonstrated the nanoparticles’ excellent biocompatibility, stability, and ability to silence TET3",2026-06-07T02:20:35+00:00
31268,toxicity_endpoint,422,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41911333; Reject under v2: luciferase/FVII siRNA LNPs are delivery-platform reporter/model knockdown tools rather than therapeutic oligonucleotide products, despite measured viability and dose-escalation toxicity.",2026-06-07T02:20:35+00:00
31269,toxicity_endpoint,423,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Even at equivalent siRNA concentrations, CaP-siSlc31a1 maintained over 80% cell viability, indicating excellent biocompatibility.",2026-06-07T02:20:35+00:00
31270,toxicity_endpoint,424,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"body weight curves (Figure S18), organ histology (Figure A), blood chemistry profiles (Figure B), and hepatic and renal function biomarkers (Figure C) in the treatment group were comparable to those in saline-treated controls, indicating tolerability during prolonged administration.",2026-06-07T02:20:35+00:00
31271,toxicity_endpoint,425,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Additionally, blood levels of platelets (thrombocytopenia), white blood cell count (inflammation), alanine aminotransferase (ALT, liver damage), and carbamide (kidney damage) had no significant changes (Fig. 2c).",2026-06-07T02:20:35+00:00
31272,toxicity_endpoint,426,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,All other formulations showed cell viability values > 80 % indicating low cytotoxicity (Fig.,2026-06-07T02:20:35+00:00
31273,toxicity_endpoint,427,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Hematoxylin and eosin (H&E) staining of major organs revealed no pathological abnormalities, and all groups showed stable increase of body weight during therapy, suggesting minimal systemic toxicity (Figure S11A,B).",2026-06-07T02:20:35+00:00
31274,toxicity_endpoint,428,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41810470; Reject: the loaded passage contains methods/planned safety assays and biodistribution, but no primary observed safety/toxicity result for MSC-NVs-siRNA; accepting would be ungrounded.",2026-06-07T02:20:35+00:00
31275,toxicity_endpoint,429,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The results collectively suggest that intranasal administration of M8NPs does not induce hepatotoxicity or impair kidney function under the tested conditions.,2026-06-07T02:20:35+00:00
31276,toxicity_endpoint,430,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Notably, no toxicity was observed with these systemically delivered siRNA polyplexes.",2026-06-07T02:20:35+00:00
31277,toxicity_endpoint,431,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41680766; Reject: the loaded passage includes the safety-test methods but no observed adverse-effect or toxicity result for the NLRP3 siRNA autonomous delivery system; accepting would be ungrounded.,2026-06-07T02:20:35+00:00
31278,toxicity_endpoint,432,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The MTT assay showed no significant differences in the viability of cells treated with PLGA NPs for 48 h at all tested concentrations (0.02, 0.04, 0.2, 0.5, 2.5 mg/mL) compared with the untreated controls, indicating that PLGA NPs did not affect cellular metabolism (Figure 5A).",2026-06-07T02:20:35+00:00
31279,toxicity_endpoint,433,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41569158; Reject: the cytotoxicity/transcriptional-misregulation statement is for the prazosin enhancer rather than a measured toxicity result of the antibody-siRNA oligo/delivery product.,2026-06-07T02:20:35+00:00
31280,toxicity_endpoint,434,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Hemolysis assays further confirmed that siB/QU@L-OL caused no detectable erythrocyte lysis at any of the tested concentrations (Fig. 1K).,2026-06-07T02:20:35+00:00
31281,toxicity_endpoint,435,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Blood biochemical analysis showed no significant difference in white blood cells (WBC), RBC, hemoglobin (HGB), and platelets (PLT) (Figures 6C-F).",2026-06-07T02:20:35+00:00
31282,toxicity_endpoint,436,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Serum biochemical markers of renal function (CREA, BUN) and hepatic function (ALT, AST) showed no significant differences compared to the control group (Fig. 9B-E).",2026-06-07T02:20:35+00:00
31283,toxicity_endpoint,437,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Compared with control groups, those treated with either empty LNP vectors or LNP-RNAs displayed normal liver, kidney, and spleen morphology, comparable body weight and organ size",2026-06-07T02:20:35+00:00
31284,toxicity_endpoint,438,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"CCK-8 assays revealed that these nanoparticles (with PB at 100 μg/mL) did not significantly affect the cell viability in BMDMs and PC12 cells (a common neuronal cell line) over periods of 24, 48, and 72 h (Fig. S6, A and B).",2026-06-07T02:20:35+00:00
31285,toxicity_endpoint,439,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The synthesized pMSNC@ISG15 siRNA nanoparticles effectively suppressed ISG15 expression in cardiac cells, exhibited excellent biocompatibility, and inhibited immune cell activation in vivo.",2026-06-07T02:20:35+00:00
31286,toxicity_endpoint,440,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,A repeat-dose tolerability study of high-dose SANG-siRNA and co-infused oxaliplatin in rats with advanced colorectal cancer42 produced no mortality or any clinical signs of distress while weights recovered back to baseline by study completion (Supplementary Fig. 20).,2026-06-07T02:20:35+00:00
31287,toxicity_endpoint,441,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Cationic and anionic siRNA lipoplexes were transfected into MCF-7-Luc and HeLa-Luc cells, with viability measured after 48 h.",2026-06-07T02:20:35+00:00
31288,toxicity_endpoint,442,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Seven out of 9 Mauritian origin NHPs developed severe TCP with platelet nadir < 50K/uL as early as after two months of treatment.,2026-06-07T02:20:35+00:00
31289,toxicity_endpoint,443,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Notably, both LNP formulations exhibited no cytotoxicity, even at high concentrations.",2026-06-07T02:20:35+00:00
31290,toxicity_endpoint,444,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Spheres made of H2.1MS1KN and a blend of H2.1MS1 and MS2KN2 silks were not cytotoxic when examined at a wide range of concentrations (Figure 4).,2026-06-07T02:20:35+00:00
31291,toxicity_endpoint,445,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40443118; Reject: the claimed renal evidence is biodistribution/exposure and kidney accumulation, not a toxicity/safety/tolerability endpoint under the toxicity contract.",2026-06-07T02:20:35+00:00
31292,toxicity_endpoint,446,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The studies conducted on red blood cells (Figure ) showed that the complexes obtained with the lower ratios (R: 3, 4, 5) were entirely compatible, with erythrolysis levels comparable to those observed when incubating cells in phosphate buffer, values attributable to the stress endured by the cells during operational procedures (e.g., centrifugation, resuspension).",2026-06-07T02:20:35+00:00
31293,toxicity_endpoint,447,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The lack of cell damage during transfection suggests that NLP-EXOSOME COMPLEX is also safe for use in the central nervous system (CNS) in vivo, and the similar results seen with parental activity indicate that the degradation of NLP-EXOSOME COMPLEX and release of the complex does not cause toxicity.",2026-06-07T02:20:35+00:00
31294,toxicity_endpoint,448,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In contrast, for the 100% P‐HyOMe‐W5:siF3 nanoparticles, FADD knockdown was maximal (60%) for 40 nM siF3. FADD silencing did not increase with increasing siRNA concentration, probably due to the dose‐dependent increase in cytotoxicity.",2026-06-07T02:20:35+00:00
31295,toxicity_endpoint,449,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Blood biochemistry and histological analyses two weeks post-injection showed no significant differences between PBS and BE(-ST)@siRNA groups (Supplementary Figs. 21, 22 and Tables 9, 10).",2026-06-07T02:20:35+00:00
31296,toxicity_endpoint,450,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"After 24 h of exposure to the complexes at a concentration of 20 µM, the viability of HUVECs remained > 90% across all the tested N: P ratios (3:1, 6:1, and 8:1), indicating the biocompatibility and nontoxicity of the nanocomplexes (Fig. 2A).",2026-06-07T02:20:35+00:00
31297,toxicity_endpoint,451,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Neither PLGA‐CpG@ID8‐M nor free CpG significantly affected cell viability at concentrations of 0–2 µm, while obvious cytotoxicity was observed at concentrations exceeding 4 µm (Figure 1F).",2026-06-07T02:20:35+00:00
31298,toxicity_endpoint,452,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,There were no significant differences in biomarkers observed between siRNA SORT LNPs and PBS groups.,2026-06-07T02:20:35+00:00
31299,toxicity_endpoint,453,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We observed an elevation in aspartate aminotransferase (AST) in the dams of IC-injected pups, and a trend for AST elevation in dams of IA-injected pups compared with dams of PBS-injected controls",2026-06-07T02:20:35+00:00
31300,toxicity_endpoint,454,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No statistical significance was detected with any formulation in any of the cell lines. Cell viability was above 60 percent in all formulations with both cell lines.,2026-06-07T02:20:35+00:00
31301,toxicity_endpoint,455,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,There were no significant effects on cell viability or cytotoxicity following exposure to NT-NPs/ASO or Phe-NPs/ASO at any of the tested concentrations,2026-06-07T02:20:35+00:00
31302,toxicity_endpoint,456,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"DOTAP/siRNA@EM having highest siRNA concentration (200 nM) displayed the lowest cytotoxicity (cell viability, ∼80 %) following 48 h-treatment.",2026-06-07T02:20:35+00:00
31303,toxicity_endpoint,457,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"At concentrations ranging from 10 to 100 µg/mL, the cell viability exceeded 90% (Fig. 2A, B).",2026-06-07T02:20:35+00:00
31304,toxicity_endpoint,458,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37963105; Reject: CAP-siRNA complexes are used for in vitro delivery/TTF-1 lab knockdown screening; no therapeutic oligonucleotide safety endpoint accepted.,2026-06-07T02:20:35+00:00
31305,toxicity_endpoint,459,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"AA-T3A-C12/siHSP47 LNP treatment slightly decreased ALT, AST, and TBIL levels in fibrotic mice, but these decreases were not significant.",2026-06-07T02:20:35+00:00
31306,toxicity_endpoint,460,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,the r/si-ORF7 displayed negligible cytotoxicity to ARPE-19 cells till 100 nM that was 10 folds higher than its working concentration (10 nM) used in antiviral experiments,2026-06-07T02:20:35+00:00
31307,toxicity_endpoint,461,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,there was no significant change found in cell viability for all three cell lines treated with MLN or MPLN compared with control,2026-06-07T02:20:35+00:00
31308,toxicity_endpoint,462,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We also found no significant differences in these markers of the liver, kidney, and heart function and body weight in comparison with controls",2026-06-07T02:20:35+00:00
31309,toxicity_endpoint,463,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The results demonstrated that the presence of CS-NPs, including at the highest concentration of CS-OA (100 μg/mL), did not affect cell viability.",2026-06-07T02:20:35+00:00
31310,toxicity_endpoint,464,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34650390; Reject: passage supports siLuc delivery/biodistribution and luciferase knockdown, not a therapeutic oligo hepatotoxicity/safety endpoint.",2026-06-07T02:20:35+00:00
31311,toxicity_endpoint,465,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,measurement of serum ALT/AST level showed that nontreated and siSTAT3/DoCh-treated group had normal level of the liver enzymes,2026-06-07T02:20:35+00:00
31312,toxicity_endpoint,466,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32366887; Reject: GNP-delivered ASO/Ps-ASO data use reporter/housekeeping-gene knockdown as a delivery screen; therapeutic oligo safety gate not met.,2026-06-07T02:20:35+00:00
31313,toxicity_endpoint,467,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 30112821; Reject: customizable LNP materials are tested with reporter siRNA/mRNA screening; mRNA is excluded and siRNA is a lab reporter tool.,2026-06-07T02:20:35+00:00
31314,toxicity_endpoint,468,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 29805475; Reject: anti-eGFP siRNA is a reporter/lab knockdown tool for delivery testing, not a therapeutic oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31315,toxicity_endpoint,469,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 29432571; weak/generic or abstract-limited support for general safety/systemic safety/tolerability.,2026-06-07T02:20:35+00:00
31316,toxicity_endpoint,470,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Compared with untreated cells, no significant reductions in cell viability were seen for any conjugate",2026-06-07T02:20:35+00:00
31317,toxicity_endpoint,471,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 27974266; Reject: polyester-siLuc nanoparticles use luciferase reporter siRNA for delivery screening; not therapeutic oligo toxicity evidence.,2026-06-07T02:20:35+00:00
31318,toxicity_endpoint,472,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40522028; the abstained record was checked at abstract level, but general safety/biocompatibility is still not directly recoverable for L2-3@siTNF-alpha LNP.",2026-06-07T02:20:35+00:00
31319,toxicity_endpoint,473,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40043858 abstract/title reviewed; no clear in-scope general safety/clinical tolerability endpoint is grounded for elebsiran (BRII-835).,2026-06-07T02:20:35+00:00
31320,toxicity_endpoint,474,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hematological/thrombocytopenia in ISIS 405879 2'-MOE ASO; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31321,toxicity_endpoint,475,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,WRN-108 was well tolerated in both species up to the highest doses tested.,2026-06-07T02:20:35+00:00
31322,toxicity_endpoint,476,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,We therefore considered the serious adverse events encountered in our two patients to be attributable to dosing of the study drug.,2026-06-07T02:20:35+00:00
31323,toxicity_endpoint,477,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The toxicity study showed that ALT levels in the TLK2 ASO group were slightly elevated, but the combination treatment reduced ALT levels.",2026-06-07T02:20:35+00:00
31324,toxicity_endpoint,478,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No significant reduction in cell viability was observed for ASO3 or ASO4 at 50 nM total ASO concentration,2026-06-07T02:20:35+00:00
31325,toxicity_endpoint,479,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In contrast, the LOTR-treated group showed hematological parameters comparable to those of the PBS control, suggesting reduced systemic toxicity.",2026-06-07T02:20:35+00:00
31326,toxicity_endpoint,480,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The characteristic features included low toxicity (maintaining >92% viable cells after 48 h of culture),2026-06-07T02:20:35+00:00
31327,toxicity_endpoint,481,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,These results demonstrate that mPEG-Azo-PEI@siRNA2 exhibits minimal non-specific toxicity toward normal cells.,2026-06-07T02:20:35+00:00
31328,toxicity_endpoint,482,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No significant changes in body weight were observed across treatment groups. Blood chemistry and histopathological analyses also confirmed the excellent biocompatibility of PLNPs, with no observable adverse effects.",2026-06-07T02:20:35+00:00
31329,toxicity_endpoint,483,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To assess acute toxicity, we analyzed the levels of alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and blood urea nitrogen (BUN) 5 hours post-injection in young adult mice. No significant changes were observed between siPAI-1 and PBS injected mice",2026-06-07T02:20:35+00:00
31330,toxicity_endpoint,484,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41640357; Reject: computational molecular-dynamics paper discusses siRNA-carrier binding and generic carrier cytotoxicity/immunogenicity, not a primary administered therapeutic oligo toxicity result.",2026-06-07T02:20:35+00:00
31331,toxicity_endpoint,485,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Subsequently, we evaluated the biosafety profiles of siLin28b+BMN673 in tumor‐free mice. Major organs including the heart, liver, spleen, lung, and kidney were collected and subjected to H&E staining. The histopathological analysis revealed no significant differences between the groups treated with siLin28b+BMN673 or vehicle, with nuclear and cellular morphologies remaining unchanged post‐treatment (Figure S10a). Consistently, a comprehensive blood analysis assessing six key toxicity parameters demonstrated comparable levels between the siLin28b+BMN673 and vehicle groups (Figure S10b), indicating no discernible impact on hepatic or renal function.",2026-06-07T02:20:35+00:00
31332,toxicity_endpoint,486,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42206267; Reject: siRNA/CRISPR are used as CRC gene-function tools and cytotoxicity refers to NK antitumor killing, not safety of a therapeutic oligonucleotide.",2026-06-07T02:20:35+00:00
31333,toxicity_endpoint,487,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42124655; Reject: vivo-morpholino is used for gene knockdown in stickleback ecology/evolution models, not a therapeutic oligonucleotide safety study.",2026-06-07T02:20:35+00:00
31334,toxicity_endpoint,488,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42072483; Reject: prostate cancer transcriptomic/axis study uses small-molecule CXCR3 modulation and viability assays; no administered therapeutic oligonucleotide toxicity evidence.,2026-06-07T02:20:35+00:00
31335,toxicity_endpoint,489,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42013544; Reject: toxicity evidence concerns copper oxide nanoparticles/asthma injury, while siRNA is only a mechanistic Nrf2 knockdown tool and is not the tested therapeutic product.",2026-06-07T02:20:35+00:00
31336,toxicity_endpoint,490,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42007882; Reject: safety/hepatotoxicity is reported for lentiviral p21 shRNA cartilage therapy, which is excluded as viral/shRNA gene therapy.",2026-06-07T02:20:35+00:00
31337,toxicity_endpoint,491,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41991930; Reject: cytotoxicity is the anticancer efficacy of the small molecule Uttroside B, with siRNA only used for EGFR mechanism validation.",2026-06-07T02:20:35+00:00
31338,toxicity_endpoint,492,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"All PMOs demonstrated favorable safety profiles, with no treatment-emergent serious adverse events related to treatment.",2026-06-07T02:20:35+00:00
31339,toxicity_endpoint,493,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41942863; Reject: AKT siRNA is a lab knockdown tool in cervical cancer chemoradiotherapy resistance assays; cytotoxicity is treatment efficacy/resistance, not oligo safety.",2026-06-07T02:20:35+00:00
31340,toxicity_endpoint,494,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41897502; Reject: toxicity/viability endpoints concern ferric citrate injury and dimercaprol small-molecule protection; NRF2 siRNA is only mechanistic knockdown.,2026-06-07T02:20:35+00:00
31341,toxicity_endpoint,495,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41894086; Reject: cytotoxicity is 5-FU cancer-cell killing/resistance and siRNA is TLR4/PTGER knockdown tool, not safety of a therapeutic oligo.",2026-06-07T02:20:35+00:00
31342,toxicity_endpoint,496,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41847637; Reject: virtual-screened DYRK1A small-molecule cytotoxicity is anticancer efficacy; siRNA knockdown is target-validation only.,2026-06-07T02:20:35+00:00
31343,toxicity_endpoint,497,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41836750; Reject: passage measures transfection-method cytotoxicity in AML cell lines using generic siRNA delivery optimization, not a named therapeutic oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31344,toxicity_endpoint,498,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41686281; Reject: glutamate/LPS-conditioned medium neurotoxicity is external injury biology and siRNA is only a p53/CREB2 knockdown tool.,2026-06-07T02:20:35+00:00
31345,toxicity_endpoint,499,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No new safety concerns were identified with long-term exposure to tofersen.,2026-06-07T02:20:35+00:00
31346,toxicity_endpoint,500,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Finally, to evaluate potential treatment-related toxicity, serum biochemical markers were assessed in mdx mice across all groups (i.e., AAV-mLVRF alone, ASO alone, or the combined mLVRF+ASO). No significant changes were detected in serum urea, albumin, or creatinine",2026-06-07T02:20:35+00:00
31347,toxicity_endpoint,501,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41598970; Reject: agricultural/insect mite pesticide toxicity and Vg RNAi knockdown are outside therapeutic oligonucleotide scope.,2026-06-07T02:20:35+00:00
31348,toxicity_endpoint,502,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41596643; Reject: cytotoxicity/safe concentration testing concerns bitter agonist small molecules in BEAS-2B cells; GNAT3 siRNA is only a lab knockdown tool.,2026-06-07T02:20:35+00:00
31349,toxicity_endpoint,503,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41568168; Reject: passage concerns AAV8 CRISPR/Cas transgene insertion and shRNA-containing AAV toxicity, both explicitly out of scope.",2026-06-07T02:20:35+00:00
31350,toxicity_endpoint,504,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41562251; Reject: the passage reports MnO2/SUPER biosafety for live-cell imaging/probe delivery, not primary toxicity evidence for an administered therapeutic oligonucleotide product.",2026-06-07T02:20:35+00:00
31351,toxicity_endpoint,505,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41545030; Reject: toxicity endpoint is doxorubicin-induced injury, while the ABCB10 ASO is used as an experimental knockdown tool rather than assessed for oligo safety.",2026-06-07T02:20:35+00:00
31352,toxicity_endpoint,506,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41527135; Reject: siALOX15B is a lab knockdown tool and the viability/cytotoxicity readout reflects tumor drug-resistance efficacy, not oligonucleotide toxicity.",2026-06-07T02:20:35+00:00
31353,toxicity_endpoint,507,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41520142; Reject: the passage concerns SMARCAL1 synthetic-lethal cancer biology/target validation, not safety or tolerability of a therapeutic oligonucleotide.",2026-06-07T02:20:35+00:00
31354,toxicity_endpoint,508,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41482385; Reject: siRNA is used for target knockdown in oral cancer biology; claimed cytotoxicity is anti-cancer efficacy, not toxicity of the oligonucleotide product.",2026-06-07T02:20:35+00:00
31355,toxicity_endpoint,509,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"despite its efficacy, g3-cys displayed a narrow therapeutic window with pronounced cytotoxicity above 1 μm. in vivo studies further confirmed dose-dependent systemic toxicity, likely associated with enhanced blood coagulation.",2026-06-07T02:20:35+00:00
31356,toxicity_endpoint,510,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"These results indicated that PURH not only significantly inhibited tumor growth, but also did not induce liver toxicity, demonstrating that PURH has good biological safety.",2026-06-07T02:20:35+00:00
31357,toxicity_endpoint,511,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To evaluate the off-target toxicity of PDL E, cytotoxicity assays were conducted using MCF-10 A cells. The results demonstrated that PDL E exhibited no detectable toxicity in these non-cancerous cells, supporting the safety profile of these exosomes for therapeutic applications (Supplementary Fig. 3).",2026-06-07T02:20:35+00:00
31358,toxicity_endpoint,512,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Vital signs and blood tests did not reveal any persistent abnormalities that could be directly attributed to the administration of elsunersen within the observed timeframe.,2026-06-07T02:20:35+00:00
31359,toxicity_endpoint,513,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"aso 8–3419 administration resulted in a moderate increase in alt levels, but no increase in ast levels (figure 8a), indicating that the toxicity of systemically administered aso 8–3419 is mild and tolerable.",2026-06-07T02:20:35+00:00
31360,toxicity_endpoint,514,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,by measuring lactate dehydrogenase (LDH) levels and identified no differences up to 200 mM (Figure 3B).,2026-06-07T02:20:35+00:00
31361,toxicity_endpoint,515,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40687881; Reject: this is a review of ASO therapies and class toxicities, without primary observed/administered/measured safety data for a specific oligonucleotide in the passage.",2026-06-07T02:20:35+00:00
31362,toxicity_endpoint,516,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The most common adverse events were back pain (six [50%]), headache (four [33%]), nausea (three [25%]), and post-lumbar puncture headache (three [25%]).",2026-06-07T02:20:35+00:00
31363,toxicity_endpoint,517,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,ASOs delivered by IA injection distributed to the spinal cord at therapeutic concentrations and to multiple peripheral tissues without evidence of significant toxicity to the fetus or mother.,2026-06-07T02:20:35+00:00
31364,toxicity_endpoint,518,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,One dose-limiting toxicity (increased alanine aminotransferase) occurred with AZD8701 960 mg.,2026-06-07T02:20:35+00:00
31365,toxicity_endpoint,519,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41463125; Reject: viability/cytotoxicity measurements are cancer-cell-killing chemosensitization efficacy readouts for miRNA-targeting ASOs, excluded by the toxicity contract.",2026-06-07T02:20:35+00:00
31366,toxicity_endpoint,520,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Chol-HDO[PMO] was well tolerated even at the highest dose (40 nmol), whereas ssMOEs exhibited lethal toxicity in a dose-dependent manner (Fig. 4b).",2026-06-07T02:20:35+00:00
31367,toxicity_endpoint,521,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41155969; Reject: the passage focuses on GIPC1 RNAi efficacy and gemcitabine-response assays; it does not provide a primary safety endpoint for the siRNA/liposomal product.,2026-06-07T02:20:35+00:00
31368,toxicity_endpoint,522,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No related adverse events were noted for any patients at the dose levels tested in the 3 + 3 Phase Ia trial,2026-06-07T02:20:35+00:00
31369,toxicity_endpoint,523,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40703143; Reject: the passage is a review/current-trials summary for Lp(a) therapies, not primary administered/measured toxicity evidence for a specific oligonucleotide.",2026-06-07T02:20:35+00:00
31370,toxicity_endpoint,524,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40609116; Reject: the abstract only states an intended safe multi-siRNA nanoparticle strategy; it does not report a primary toxicity/safety/tolerability result.,2026-06-07T02:20:35+00:00
31371,toxicity_endpoint,525,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39385468; Reject: the intervention is LNP-CRISPR-Cas9 gene editing, which is explicitly excluded from scope even though safety endpoints are mentioned.",2026-06-07T02:20:35+00:00
31372,toxicity_endpoint,526,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40473123; Reject: SARM1 ASOs are used to protect neurons from external vacor/SARM1-activation toxicity; the endpoint is not toxicity of the administered ASO product.,2026-06-07T02:20:35+00:00
31373,toxicity_endpoint,527,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"STP705 demonstrated a favorable safety profile with no clinically significant changes in lab values, vital signs, or ECGs.",2026-06-07T02:20:35+00:00
31374,toxicity_endpoint,528,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"As for the measurement of biochemical indicators, compared to the model group, there were no significant differences in AST, ALT, BUN, or CRE activity among the mice in each group (Table 4).",2026-06-07T02:20:35+00:00
31375,toxicity_endpoint,529,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Analysis of toxicity indicators iba1 and gfap in the thalamus and hippocampus—regions closest to the injection site with the highest siRNA accumulation and activity (8)—showed no observed changes, supporting the safety of D-siRNA (Figure 2B, right panel).",2026-06-07T02:20:35+00:00
31376,toxicity_endpoint,530,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Compared to the controls, the 40 mg/kg and 40 mg/kg/2wks treatments did not increase liver (ALT) or kidney (BUN) damage markers",2026-06-07T02:20:35+00:00
31377,toxicity_endpoint,531,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The animals can well tolerate the challenge of repeat doses of KC13-M2G2 even at the highest tested dose of 200 mg/kg,2026-06-07T02:20:35+00:00
31378,toxicity_endpoint,532,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41239436; Reject: agricultural/vector-control dsRNA work in Aedes albopictus is explicitly out of toxicity-domain therapeutic oligonucleotide scope despite cytotoxicity and larval mortality assays.,2026-06-07T02:20:35+00:00
31379,toxicity_endpoint,533,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"At 12.5 µM, the treatment group exhibited cytotoxic effects comparable to those of the positive control (10% DMSO), showing statistically significant toxicity in HEp-2 and A549 cells",2026-06-07T02:20:35+00:00
31380,toxicity_endpoint,534,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41030277; Reject: evidence concerns engineered bacterial extracellular vesicles delivering/expressing shRNA for cancer therapy; shRNA is a stated scope exclusion.,2026-06-07T02:20:35+00:00
31381,toxicity_endpoint,535,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40943389; Reject: decreased pancreatic cancer cell viability and apoptosis are antitumor efficacy readouts, not safety or tolerability of the siRNA product.",2026-06-07T02:20:35+00:00
31382,toxicity_endpoint,536,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40927452; Reject: fungal/locoweed agricultural toxicity mitigation is outside therapeutic oligonucleotide scope and the toxicity is swainsonine/livestock poisoning, not oligo safety.",2026-06-07T02:20:35+00:00
31383,toxicity_endpoint,537,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40873646; Reject: reported neurotoxicity/apoptosis endpoints are A? disease-injury efficacy readouts; no primary genotoxicity or safety endpoint is tied to the siRNA nanocomplex.,2026-06-07T02:20:35+00:00
31384,toxicity_endpoint,538,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"after NagZ-PPNA treatment at 2 and 4 µM, values of this parameter were ca. 6% and 10% respectively",2026-06-07T02:20:35+00:00
31385,toxicity_endpoint,539,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Dendrimers 2 and 3 were biocompatible in PBMCs up to 1 and 0.5 μM, respectively, and slightly higher concentrations in THP-1 (1 μM).",2026-06-07T02:20:35+00:00
31386,toxicity_endpoint,540,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We provide a detailed examination of regional bulk tissue gene silencing in mice, highlighting potent knockdown 5 months after a single injection without detectable toxicity.",2026-06-07T02:20:35+00:00
31387,toxicity_endpoint,541,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40457499; Reject: genome-wide siRNA screen uses oligos as lab knockdown tools to study ?Syn-induced toxicity, not as administered therapeutic oligonucleotide safety evidence.",2026-06-07T02:20:35+00:00
31388,toxicity_endpoint,542,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40407475; Reject: safety endpoints are for empagliflozin, a small molecule; oligonucleotides appear only as background therapeutic approaches.",2026-06-07T02:20:35+00:00
31389,toxicity_endpoint,543,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 40259913; pmc_full_text evidence was direct but less than full primary-detail confidence for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31390,toxicity_endpoint,544,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Tyrosine-modified nanoparticles, in particular P10Y-based polyplexes or lipopolyplexes, showed the highest biocompatibility.",2026-06-07T02:20:35+00:00
31391,toxicity_endpoint,545,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,the cell survival in the samples treated with nanocarrier/siRNA complex at 10 and 20 nanomolar concentrations was 99.3% and 99.2%,2026-06-07T02:20:35+00:00
31392,toxicity_endpoint,546,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No changes in IL-8, IL-6, and IFN-γ releases were observed after CaP-siRNA or, CaP-scramble (Figure 3B–D).",2026-06-07T02:20:35+00:00
31393,toxicity_endpoint,547,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39784355; Reject: Pdot-siRNA toxicity is measured for a generic Gapdh gene-expression nanotool, not a therapeutic oligonucleotide or disease-directed product.",2026-06-07T02:20:35+00:00
31394,toxicity_endpoint,548,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,neither the single 400 µg dose nor the 300 µg repeated doses of asiRNA-VP-DCA induced any signs of toxicity or mortality in either treatment group,2026-06-07T02:20:35+00:00
31395,toxicity_endpoint,549,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41675514; Reject: ADAM10 study relies on antibody/small-molecule and shRNA target-validation/cancer viability assays; no therapeutic oligo safety result is present.,2026-06-07T02:20:35+00:00
31396,toxicity_endpoint,550,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41471099; Reject: current toxicity measurements concern a protein toxin delivery assay and siRNA is used mechanistically for transfection/intermediary tracking, not therapeutic oligo safety.",2026-06-07T02:20:35+00:00
31397,toxicity_endpoint,551,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In contrast, no measurable IRF activation was detected for complexes containing RNA fibers or DS RNA with either MSN-PEI formulation.",2026-06-07T02:20:35+00:00
31398,toxicity_endpoint,552,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41347876; Reject: SMS2 siRNA is a mechanistic knockdown tool in oxidative-stress dry-eye biology; reduced cytotoxicity reflects protection from external H2O2 injury, not oligo safety.",2026-06-07T02:20:35+00:00
31399,toxicity_endpoint,553,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41339338; Reject: thymic cancer proteasome-inhibitor study has no therapeutic oligonucleotide; cell viability/cytotoxicity belongs to small-molecule anticancer efficacy.,2026-06-07T02:20:35+00:00
31400,toxicity_endpoint,554,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41304847; Reject under v2: VDAC1 siRNA is used as an in vitro perturbation tool in BPAF toxin-injury biology; toxicity endpoints reflect BPAF/external injury, not safety of a therapeutic oligonucleotide or delivery product.",2026-06-07T02:20:35+00:00
31401,toxicity_endpoint,555,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41301860; Reject under v2: study evaluates acetylsalicylic acid and recombinant APE1/Ref-1 protein/adenoviral approaches in cancer, with no therapeutic oligonucleotide safety evidence.",2026-06-07T02:20:35+00:00
31402,toxicity_endpoint,556,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"exhibited excellent safety profiles, without body weight changes at 24 h and 48 h post-administration",2026-06-07T02:20:35+00:00
31403,toxicity_endpoint,557,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41290726; Reject under v2: toxicity is caused by DON/FB1 mycotoxins and Caspase 6 siRNA is a pathway knockdown tool, not the administered therapeutic product whose safety is measured.",2026-06-07T02:20:35+00:00
31404,toxicity_endpoint,558,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41256290; Reject under v2: DMPK gapmer/siRNA are evaluated for biomarker or therapeutic-response readouts in cell models, with no primary toxicity, safety, or tolerability endpoint linked to the oligo.",2026-06-07T02:20:35+00:00
31405,toxicity_endpoint,559,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41233563; Reject under v2: RNAi-mediated MET knockdown is laboratory validation of thyroid cancer migration/invasion biology, not therapeutic oligonucleotide safety evidence.",2026-06-07T02:20:35+00:00
31406,toxicity_endpoint,560,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The results shown in Figure 3 indicate that no significant differences in cytotoxicity were observed among the coated polyplexes across all tested charge ratios in MDA-MB-231 cells.,2026-06-07T02:20:35+00:00
31407,toxicity_endpoint,561,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41168832; Reject under v2: MALAT1 ASO readouts concern endogenous lncRNA biology, drug-resistance reversal, and cancer-cell viability/cell death efficacy, not safety or tolerability of the oligo.",2026-06-07T02:20:35+00:00
31408,toxicity_endpoint,562,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41163839; Reject under v2: siRNA is used to induce or model Gaucher disease while treatment is N-acetylglycine hydrogel; no therapeutic oligonucleotide toxicity evidence is measured.,2026-06-07T02:20:35+00:00
31409,toxicity_endpoint,563,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41115949; Reject under v2: Thy1-ASO refers to a disease mouse model context, not an administered antisense oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31410,toxicity_endpoint,564,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41049425; Reject under v2: Protodioscin is a small molecule/natural product cancer therapy and the readouts are antitumor apoptosis/efficacy, not oligonucleotide safety.",2026-06-07T02:20:35+00:00
31411,toxicity_endpoint,565,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No significant adverse effects were observed through apoptosis assays or ERG.,2026-06-07T02:20:35+00:00
31412,toxicity_endpoint,566,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"H&E staining of major organs, including the heart, liver, spleen, and kidneys, showed no lesions, histopathological injuries, or abnormalities caused by the inhalation of mscFv/siPD-L1@LNP (Supplementary Fig. 24b).",2026-06-07T02:20:35+00:00
31413,toxicity_endpoint,567,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40869421; Reject under v2: TG2 siRNA is a lab knockdown used to alter cisplatin sensitivity in MCF-7 cancer cells; cytotoxicity is cancer efficacy/drug-response, not oligo safety.",2026-06-07T02:20:35+00:00
31414,toxicity_endpoint,568,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 40848064; weak/generic or abstract-limited support for general safety/cell viability/cytotoxicity.,2026-06-07T02:20:35+00:00
31415,toxicity_endpoint,569,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40843899; Reject under v2: CHO-cell engineering uses CRISPR/shRNA, which is explicitly out of scope, and does not report therapeutic oligonucleotide safety.",2026-06-07T02:20:35+00:00
31416,toxicity_endpoint,570,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40787447; Reject under v2: programmed-cell-death/microglial study uses siRNA for functional validation of disease biology, with no therapeutic oligo safety endpoint.",2026-06-07T02:20:35+00:00
31417,toxicity_endpoint,571,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 40645721; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31418,toxicity_endpoint,572,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"These data support that systemically administered PPMO6 resulted in a better targeting of DNM2 level in the muscle than in the liver, with no signs of toxicity in the liver.",2026-06-07T02:20:35+00:00
31419,toxicity_endpoint,573,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40607388; Reject under v2: genome-wide shRNA screen is explicitly out of scope, and NK cytotoxicity/degranulation assays are immune-function readouts rather than oligo safety.",2026-06-07T02:20:35+00:00
31420,toxicity_endpoint,574,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Comprehensive safety evaluation (Figure 6) demonstrated that LNP-sRNA treatment did not adversely affect physiological parameters such as food intake or body weight over a 14-day treatment period.,2026-06-07T02:20:35+00:00
31421,toxicity_endpoint,575,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40553247; Reject under v2: LN-53 is a small-molecule 2-oxopyrrolidine derivative/Nrf2 activator, not an oligonucleotide therapeutic.",2026-06-07T02:20:35+00:00
31422,toxicity_endpoint,576,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In the CCK-8 assay, compared to the control group, single si-Cx43-NPs, single Avastin, non-loaded hydrogel, Avastin-hydrogel, and si-Cx43-NPs@Avastin-hydrogel did not significantly reduce cell viability, indicating low cytotoxicity, whereas cisplatin significantly suppressed cell viability (Fig. 3B).",2026-06-07T02:20:35+00:00
31423,toxicity_endpoint,577,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40498020; Reject under v2: TRPC3-targeting siRNA is a laboratory knockdown in amyloid-beta neuronal biology; synaptotoxicity reflects disease/toxin biology, not oligo safety.",2026-06-07T02:20:35+00:00
31424,toxicity_endpoint,578,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Here, we found no significant difference between any treatment groups suggesting no apparent toxic effects of DG9-PMO on the kidney.",2026-06-07T02:20:35+00:00
31425,toxicity_endpoint,579,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40365296; Rejected: claimed CD8 cytotoxicity is antitumor immune-cell killing in an iPSC/CpG vaccine study, not toxicity of a therapeutic oligonucleotide product.",2026-06-07T02:20:35+00:00
31426,toxicity_endpoint,580,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40311681; Rejected: SPTBN1 siRNA is used as a mechanistic knockdown tool to block ammonia toxicity/signaling, not as an administered therapeutic oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31427,toxicity_endpoint,581,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 40297405; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31428,toxicity_endpoint,582,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40264356; Rejected: Parkin siRNA is only a lab knockdown tool in black phosphorus nanoparticle placental toxicity, where the nanoparticle is the toxic exposure.",2026-06-07T02:20:35+00:00
31429,toxicity_endpoint,583,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 40236812; pmc_full_text evidence was direct but less than full primary-detail confidence for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31430,toxicity_endpoint,584,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40235854; Rejected: single-guide RNA Cas9/EDCas9 is CRISPR genome editing, explicitly out of scope for the toxicity contract.",2026-06-07T02:20:35+00:00
31431,toxicity_endpoint,585,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40227445; Rejected: study concerns a gastrodin small-molecule derivative; siRNA appears only in target-mechanism validation, not oligonucleotide therapeutic safety.",2026-06-07T02:20:35+00:00
31432,toxicity_endpoint,586,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The results indicated that there was no significant decrease of NIH3T3s viability when the si-ITGA6-loaded liposomes reached a concentration of 200 nM,2026-06-07T02:20:35+00:00
31433,toxicity_endpoint,587,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"VCA-894A administration on days 1, 29, 57, and 85 was well tolerated at all dose levels and there were no unscheduled deaths during the course of the study.",2026-06-07T02:20:35+00:00
31434,toxicity_endpoint,588,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted A->B: PMID 39946362; pmc_full_text evidence was direct but less than full primary-detail confidence for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31435,toxicity_endpoint,589,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 39838063; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31436,toxicity_endpoint,590,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39698891; Rejected: siRNA-mediated CSB loss-of-expression is a mechanistic knockdown tool for UVB cytotoxicity/senescence, not therapeutic oligonucleotide toxicity.",2026-06-07T02:20:35+00:00
31437,toxicity_endpoint,591,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41378010; Rejected: shRNA targeting lncRNA OIP5-AS1 is used to study NSCLC biology; no therapeutic oligonucleotide safety/tolerability endpoint is grounded.,2026-06-07T02:20:35+00:00
31438,toxicity_endpoint,592,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41234867; Rejected: shRNA-engineered CAR-T cells are outside scope, and the claimed cytotoxicity is antileukemia CAR-T killing efficacy rather than oligonucleotide toxicity.",2026-06-07T02:20:35+00:00
31439,toxicity_endpoint,593,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40331953; Rejected: HMGB1 siRNA is a cell-line knockdown tool for HCC metastasis/drug-sensitivity biology, not an administered therapeutic oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31440,toxicity_endpoint,594,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40171277; Rejected: CAG-targeted shRNAs are delivered by AAV-PHP.eB vectors; AAV/viral gene therapy and shRNA-vector therapy are excluded.,2026-06-07T02:20:35+00:00
31441,toxicity_endpoint,595,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40096771; Rejected: BARD1 siRNAs/CRISPR are used as genetic inhibition tools for PDAC target validation; toxicity-to-mice wording is not tied to a named therapeutic oligonucleotide product.,2026-06-07T02:20:35+00:00
31442,toxicity_endpoint,596,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39401270; Rejected: apMNKQ2 aptamer nanoconjugate viability reduction is a breast-cancer cell killing/transfection-efficacy readout, which the toxicity contract excludes as efficacy cytotoxicity.",2026-06-07T02:20:35+00:00
31443,toxicity_endpoint,597,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38501046; Rejected: passage primarily reports ASO chemistry, uptake, and knockdown activity; no grounded observed toxicity/safety endpoint for the modified ASOs is present.",2026-06-07T02:20:35+00:00
31444,toxicity_endpoint,598,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Reducing the PS content of gapmer ASOs, which contain a stretch of PS-DNA, improves their toxicity profile, but in some cases also reduces efficacy or duration of effect.",2026-06-07T02:20:35+00:00
31445,toxicity_endpoint,599,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39377066; Rejected: loaded passage only grounds hepatotoxicity measurement methods for REST_SSO and tumor-cell viability efficacy; it does not provide an observed hepatotoxicity/safety result.,2026-06-07T02:20:35+00:00
31446,toxicity_endpoint,600,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"ION-827359 was well tolerated with an acceptable safety profile. There were no clinically relevant changes in laboratory values, ECG or vital signs.",2026-06-07T02:20:35+00:00
31447,toxicity_endpoint,601,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Conversely, mice administered sbASO.miR-483 exhibited severe adverse phenotypes, including ataxia and orofacial dyskinesia, resulting in euthanasia before the full 5-day postimplantation period.",2026-06-07T02:20:35+00:00
31448,toxicity_endpoint,602,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Clinical signs of CARPA were not observed, and occasional mild and transient hepatotoxicity was present in siPLG-treated animals at 5 h post-infusion, which returned to baseline by 7 days.",2026-06-07T02:20:35+00:00
31449,toxicity_endpoint,603,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 38276948; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31450,toxicity_endpoint,604,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Cell viability assays in THP1 Dual cells revealed an approximately 50% reduction in viability when NANP-siRhoAs were complexed with the L2K carrier (Fig. 8A).,2026-06-07T02:20:35+00:00
31451,toxicity_endpoint,605,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The lipopolymers did not induce the secretion of proinflammatory cytokines (IL-6, TNF-α, and INF-γ) in PBMCs from healthy volunteers, underscoring their immune safety profile.",2026-06-07T02:20:35+00:00
31452,toxicity_endpoint,606,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39189114; Rejected: passage discusses siRNA cross-species potency/efficacy and the general need to assess toxicity in development, but gives no primary administered/measured toxicity endpoint.",2026-06-07T02:20:35+00:00
31453,toxicity_endpoint,607,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"While the TRIFAPYs did not show significant toxicity by themselves at 1.5 µg/mL, the compounds containing alkyl chains from C12 through C18 showed a clear effect in decreasing cell viability when combined with the PPRH.",2026-06-07T02:20:35+00:00
31454,toxicity_endpoint,608,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Biocompatibility studies indicated no cytotoxicity of MDs-NFATc1/PLA-Exo scaffolds in RAW 264.7 macrophages and hBMSCs.,2026-06-07T02:20:35+00:00
31455,toxicity_endpoint,609,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Mice injected with Chol-siRNAHTT/Htt and DCA-siRNAHTT/Htt exhibited phenotypic hallmarks of acute oligonucleotide-induced neurotoxicity,2026-06-07T02:20:35+00:00
31456,toxicity_endpoint,610,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39713235; Rejected: ASO in this article means arterial switch operation, not antisense oligonucleotide; no therapeutic oligo toxicity endpoint is present.",2026-06-07T02:20:35+00:00
31457,toxicity_endpoint,611,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"However, there was no statistical difference in cell activity between the experimental groups and the control group at the same time point, indicating that different concentrations of drugs had no significant effect on cell viability.",2026-06-07T02:20:35+00:00
31458,toxicity_endpoint,612,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39638605; Rejected: evidence concerns cepharanthine, a small-molecule natural compound for African swine fever, not a therapeutic oligonucleotide product.",2026-06-07T02:20:35+00:00
31459,toxicity_endpoint,613,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39588258; Rejected: therapeutic GapmeR nanoparticles are in scope, but the loaded passage only states that organ toxicity was assessed; no primary observed toxicity result is grounded in the passage.",2026-06-07T02:20:35+00:00
31460,toxicity_endpoint,614,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39574582; Rejected: passage reports HTT-lowering effects on hepatic somatic instability/transcription, an on-target mechanistic/efficacy outcome, not safety or hepatotoxicity of the oligo.",2026-06-07T02:20:35+00:00
31461,toxicity_endpoint,615,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"HOXB7 silencing associated with TMX administration promoted controlled tumor growth, as well as a higher survival rate and reduction in immuno- and hepatotoxicity.",2026-06-07T02:20:35+00:00
31462,toxicity_endpoint,616,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Overall, there were no serious adverse events related to nusinersen use in the pediatric cohort.",2026-06-07T02:20:35+00:00
31463,toxicity_endpoint,617,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38859589; Rejected: siRNA-tMNV endpoints are antitumor immune activation and tumor-cell cytotoxicity efficacy, not toxicity/safety of the oligo delivery product.",2026-06-07T02:20:35+00:00
31464,toxicity_endpoint,618,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38819691; Rejected: review/platform discussion of nanoinjection and ex vivo cell engineering, with no primary administered therapeutic oligo toxicity result.",2026-06-07T02:20:35+00:00
31465,toxicity_endpoint,619,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38785527; Rejected: toxicity evidence concerns cisplatin and chemoresistant hepatocellular carcinoma biology, not an administered therapeutic oligonucleotide safety endpoint.",2026-06-07T02:20:35+00:00
31466,toxicity_endpoint,620,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38658865; Rejected: evidence concerns homoharringtonine/cytarabine small-molecule chemotherapy toxicity and apoptosis mechanisms, not therapeutic oligo toxicity.",2026-06-07T02:20:35+00:00
31467,toxicity_endpoint,621,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38558246; Rejected: TUG1 ASO is used to restore cisplatin sensitivity; the cytotoxicity/viability endpoint is cancer-cell-killing efficacy, not safety of the oligo product.",2026-06-07T02:20:35+00:00
31468,toxicity_endpoint,622,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We describe here the first case of exposure to patisiran treatment, a small interfering RNA molecule, during early pregnancy of a 36-year-old woman with symptomatic hereditary transthyretin-related amyloidosis. There were no major complications during pregnancy and delivery, except for a postpartum hemorrhage due to uterine atony.",2026-06-07T02:20:35+00:00
31469,toxicity_endpoint,623,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Two participants (3.0%) experienced suspected or confirmed thromboembolic events with fitusiran.,2026-06-07T02:20:35+00:00
31470,toxicity_endpoint,624,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38429789; Rejected: toxicity profile concerns bocodepsin/doxorubicin small-molecule therapy, not a therapeutic oligonucleotide product.",2026-06-07T02:20:35+00:00
31471,toxicity_endpoint,625,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 38383439; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31472,toxicity_endpoint,626,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38351187; Rejected: HUDSON includes a STAT3 ASO regimen, but the grounded safety passages are aggregate/multi-regimen or non-ASO-specific and do not link a toxicity endpoint specifically to the oligo product.",2026-06-07T02:20:35+00:00
31473,toxicity_endpoint,627,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The siRNA/AuPEI cells in the application groups, assessed by the WST-1 technique, had a viability rate of over 90%, indicating no toxicity or side effects.",2026-06-07T02:20:35+00:00
31474,toxicity_endpoint,628,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->C: PMID 39539970; weak/generic or abstract-limited support for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
31475,toxicity_endpoint,629,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Conversely, even at elevated concentrations, cRGD-PEG-siNC treatment did not significantly affect cell viability compared to the control group, except at 2000 nM where viability decreased to 90.03%.",2026-06-07T02:20:35+00:00
31476,toxicity_endpoint,630,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39057271; Reject: agricultural Varroa RNAi/beekeeper survey article; no therapeutic oligonucleotide was administered or measured for a safety/toxicity endpoint.,2026-06-07T02:20:35+00:00
31477,toxicity_endpoint,631,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In the cell viability test in immortalized microglia cells (IMG), the hybrid nanocomposite (NP) exhibited no significant effect on cell survival after 48 hours of incubation.",2026-06-07T02:20:35+00:00
31478,toxicity_endpoint,632,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39776903; Reject: siRNA was a knockdown tool used to engineer/perturb CAR-NK cells; viability after transfection is not a therapeutic oligonucleotide safety endpoint.,2026-06-07T02:20:35+00:00
31479,toxicity_endpoint,633,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39741316; Reject: passage concerns daidzein/lovastatin myotoxicity and mechanistic biology; the toxicity endpoint is not linked to an administered therapeutic oligonucleotide.,2026-06-07T02:20:35+00:00
31480,toxicity_endpoint,634,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Cell viability remained stable at concentrations up to 40 μg/mL (Figure S3A–D), indicating their good biocompatibility.",2026-06-07T02:20:35+00:00
31481,toxicity_endpoint,635,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39588262; Reject: the cited cytotoxicity is tumor-cell killing/anticancer efficacy, and the body-weight text is not clearly tied to the siRNA-containing therapeutic product.",2026-06-07T02:20:35+00:00
31482,toxicity_endpoint,636,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39452993; Reject: MTT cytotoxicity is breast-cancer-cell killing efficacy of the PTX/GEM/siRNA triple therapy, which the toxicity contract excludes.",2026-06-07T02:20:35+00:00
31483,toxicity_endpoint,637,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39369270; Reject: the abstract infers reduced chemotherapy-associated toxicity from dose reduction but does not provide a primary measured safety/toxicity endpoint for the oligo product.,2026-06-07T02:20:35+00:00
31484,toxicity_endpoint,638,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39339274; Reject: safety/cytotoxicity results concern small-molecule CDK8 inhibitors, not an administered therapeutic oligonucleotide.",2026-06-07T02:20:35+00:00
31485,toxicity_endpoint,639,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Throughout this period, there was no change in body weight or abnormal elevation in ALT levels in the BRO-treated arm (Fig. 2f, g).",2026-06-07T02:20:35+00:00
31486,toxicity_endpoint,640,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Other JEV-RNA-targeted and control LNA gapmers were not toxic in SK-N-SH cells at any concentration tested.,2026-06-07T02:20:35+00:00
31487,toxicity_endpoint,641,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No adverse effects were observed in either group and no change in body weight occurred for the duration of the treatment course ( Figure 3B ).,2026-06-07T02:20:35+00:00
31488,toxicity_endpoint,642,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In mice, oral administration of SH-BC-893 increased ASO potency in the liver by 15-fold without toxicity.",2026-06-07T02:20:35+00:00
31489,toxicity_endpoint,643,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Mouse weight, a surrogate to assess potential treatment toxicity, remained stable over the course of therapy for Control ASO and T-RECS ASO in all cohorts (Fig.",2026-06-07T02:20:35+00:00
31490,toxicity_endpoint,644,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Although Atp1a2 ASO-treated mice displayed no off-target or systemic toxicity, the ASO-treated mice exhibited an accelerated disease onset and shorter lifespan than control mice.",2026-06-07T02:20:35+00:00
31491,toxicity_endpoint,645,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37836816; Reject: aptamer is used in an analytical silver-enhanced assay for antimony ions in water, not as a therapeutic administered oligonucleotide.",2026-06-07T02:20:35+00:00
31492,toxicity_endpoint,646,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Finally, to check for possible CPP-PMO-mediated immune system activation, the bodyweight-normalized spleen weight (Figure S6A) and weight gain or loss (Figures S6B and S6C) were analyzed in each experimental group, with no significant between-group changes found.",2026-06-07T02:20:35+00:00
31493,toxicity_endpoint,647,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38019311; Reject: G2C4/G4C2 ASO results are target engagement and neuronal-dysfunction biology; the cell-viability assay is glutamate-induced neuronal death, not ASO safety/toxicity.",2026-06-07T02:20:35+00:00
31494,toxicity_endpoint,648,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The subcutaneous administration of Notch3 mutant ASO at 50 mg/Kg decreased Notch6691-TTATGA mRNA in bone without apparent toxicity;,2026-06-07T02:20:35+00:00
31495,toxicity_endpoint,649,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36814640; Reject: passage discusses IAPP disease-protein toxicity and ASO efficacy/dosing; no primary oligonucleotide safety, tolerability, or toxicity endpoint is reported.",2026-06-07T02:20:35+00:00
31496,toxicity_endpoint,650,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In addition, no obvious histological toxicity and inflammation infiltrates were observed in major organs of mice, including the brain, heart, liver, spleen, lung, and kidney, after different treatments at the highest siRNA doses (Supporting Information Fig. S17).",2026-06-07T02:20:35+00:00
31497,toxicity_endpoint,651,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The results of the cytotoxicity assay demonstrated the CoV-2-RBD-1C aptamer’s excellent adaptability and, as a consequence, reflected its economic advantage due to low concentration could be used.",2026-06-07T02:20:35+00:00
31498,toxicity_endpoint,652,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No adverse events were reported after inclisiran administration and LDL-C levels decreased significantly, confirming the evidence that this innovative approach to hypercholesterolemia is a safe and effective resource in patients at high CV risk who cannot achieve LDL-C goal with conventional lipid-lowering therapies and antibody-based PCSK9i.",2026-06-07T02:20:35+00:00
31499,toxicity_endpoint,653,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37373287; Reject: LPS/mgmt macrophage toxicity and cytokine endpoints are genetic/immune biology, with no therapeutic oligonucleotide administered or evaluated for safety.",2026-06-07T02:20:35+00:00
31500,toxicity_endpoint,654,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Adverse events (AEs) were reported in 22 of 33 (66.6%) RO7062931 recipients (n = 80 treatment‐related) and seven of eight (87.5%) placebo recipients (n = 1 treatment‐related). Apart from two moderate‐intensity AEs, all AEs were mild.",2026-06-07T02:20:35+00:00
31501,toxicity_endpoint,655,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37050317; Rejected: PI3K morpholino-purine derivatives are small-molecule kinase inhibitors, not therapeutic oligonucleotides.",2026-06-07T02:20:35+00:00
31502,toxicity_endpoint,656,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No toxicities or adverse effects were observed in any cohort receiving inclisiran, either alone or in combination.",2026-06-07T02:20:35+00:00
31503,toxicity_endpoint,657,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Vupanorsen was well‐tolerated with no treatment‐related adverse events reported for either dose.,2026-06-07T02:20:35+00:00
31504,toxicity_endpoint,658,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The treatment ameliorated the atrophic musculature and improved breathing function accompanied by improved muscle strength and innervation at the neuromuscular junction with no signs of apparent toxicity.,2026-06-07T02:20:35+00:00
31505,toxicity_endpoint,659,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Safety and toxicity studies were performed in immune competent mice after short or long-term exposure and showed no off-target toxicity by histological or biochemical evaluation.,2026-06-07T02:20:35+00:00
31506,toxicity_endpoint,660,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Even at the highest dose used (150 mg/kg), the gap2 OMe-modified ASO did not cause ALT/AST elevation.",2026-06-07T02:20:35+00:00
31507,toxicity_endpoint,661,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Mice treated with 100 μg of ASO-001933 ICV showed robust tau mRNA reduction by 80% 72 h post dosing and no obvious acute in vivo signs as indicated by a tolerability scores of <1 in a modified Irwin battery31 (Figure 2C).,2026-06-07T02:20:35+00:00
31508,toxicity_endpoint,662,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Histopathology analyses of brain, spinal cord (lumbar, thoracic, and cervical), and dorsal root ganglia tissues indicated that the single 20-mg dose of ASO-005-02, ASO-059, or ASO-066 to cynomolgus monkeys via intrathecal injection did not result in any test item-related gross or microscopic changes at study termination (Figure S11).",2026-06-07T02:20:35+00:00
31509,toxicity_endpoint,663,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35080855; Rejected: anti-HIF-1-alpha ASO-nanodisc cell viability decrease is target-mediated cancer-cell survival/efficacy, while other toxicity mentions are background or prior trials, not a primary safety result for this study.",2026-06-07T02:20:35+00:00
31510,toxicity_endpoint,664,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"As shown in Fig 3B, the cell viability was not changed at the concentrations of LNP tested (0.1 to 50 μM). Similarly, insignificant levels of LDH release were detected in the supernatant of cultured cells, indicating that cells remained healthy following our treatment with LNP-S60 (Fig 3C).",2026-06-07T02:20:35+00:00
31511,toxicity_endpoint,665,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The compound was also well tolerated in mice upon i.v. administration up to a dose of 20 mg/kg, and in vivo fluorescence imaging indicated clearance via renal excretion with slight accumulation in the kidneys and liver.",2026-06-07T02:20:35+00:00
31512,toxicity_endpoint,666,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"There was no detectable hepatotoxicity or effect on platelets, and no treatment-related changes were observed in hepatic function based on transaminases or severe thrombocytopenia.",2026-06-07T02:20:35+00:00
31513,toxicity_endpoint,667,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35852833; Rejected: toxic/safe PS-ASOs are used as mechanistic cell-transfection tools to study RNase H1 partners, not an administered therapeutic oligonucleotide or delivery-product safety endpoint.",2026-06-07T02:20:35+00:00
31514,toxicity_endpoint,668,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Neither ASO produced adverse behavioral side effects; all animals remained healthy until they were sacrificed at 21 days. Routine clinical blood chemistry and liver and kidney morphology after H&E staining revealed no gross abnormalities.,2026-06-07T02:20:35+00:00
31515,toxicity_endpoint,669,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35692770; Rejected: the passage concerns epirubicin and radioactive iodine seed anticancer effects, with no therapeutic oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31516,toxicity_endpoint,670,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The introduced iRGD keeps tumor-targeting and -penetrating bioactivity, which endows iRGD-NPs with ~100% of tumor-cell uptake and excellent tumor spheroid-penetration, and thus iRGD-NPs can efficiently deliver siVEGF to significantly inhibit angiogenesis in zebrafish and tumor growth in nude mice bearing breast cancer without obvious toxicity.",2026-06-07T02:20:35+00:00
31517,toxicity_endpoint,671,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"As a contrast, insignificant inflammation and negligible necrotic cells could be observed in HA-SeSe-COOH/siR-93C@PAMAM treated group, indicating that the outer layer HA-SeSe-COOH did significantly improve the biosafety of PAMAM.",2026-06-07T02:20:35+00:00
31518,toxicity_endpoint,672,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Indeed, the median lethal dose (LD50) occurs at a higher siRNA concentration with hairpin-like siRNA-SNAs than with hybridized siRNA-SNAs, indicating that the hairpin-like architecture is less cytotoxic.",2026-06-07T02:20:35+00:00
31519,toxicity_endpoint,673,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36421975; Rejected: dsRNA silencing is agricultural pest-control RNAi in Phyllotreta striolata, explicitly out of scope.",2026-06-07T02:20:35+00:00
31520,toxicity_endpoint,674,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36296424; Rejected: nucleic-acid templating haplomers are an in vitro assembly/proof-of-concept system; toxicity refers to desired target-cell killing or background chemotherapy toxicity, not oligo safety.",2026-06-07T02:20:35+00:00
31521,toxicity_endpoint,675,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35204815; Rejected: siRNA is a tool to silence IDE and modulate carfilzomib cytotoxicity; the toxicity endpoint belongs to the small-molecule drug, not the oligonucleotide product.",2026-06-07T02:20:35+00:00
31522,toxicity_endpoint,676,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"During the three weeks of treatment, no obvious gross abnormalities were observed. Furthermore, we did not detect any histological abnormalities in the various organs in either mASO3-cEt/DNA-treated, Ctrl-cEt/DNA-treated, or saline-treated mice after three weeks of treatment (Fig. 6H). In a separate experiment, we assessed alanine transaminase (ALT) and aspartate transaminase (AST) levels in serum collected from C57BL6 mice that were administered subcutaneous injections of either saline or mASO3-cEt/DNA at 100 mg/kg/wk for 4 weeks. We did not detect any significant difference in either of the transaminase plasma levels. Similar to mASO3-cEt/DNA treatment in FVB/N mice, the C57BL6 mice likewise did not show significant differences in organ weights or total body weight (Supplementary Fig. 8C–E). These observations indicate that mASO3-cEt/DNA is well tolerated in both wild-type FVB/N mice and C57BL6 mice.",2026-06-07T02:20:35+00:00
31523,toxicity_endpoint,677,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"However, in stark contrast to Kasumi-1 cells, where LNP-si-LINC01257 significantly decreased cell growth and viability, treatment with LNP-si-LINC01257 exerted a negligible impact on the viability of all three PBMC populations, with no difference in viability observed in monocytes and T cells, and a small but non-significant increase in B cell viability (Figure 6E and Figure S4B).",2026-06-07T02:20:35+00:00
31524,toxicity_endpoint,678,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Our results demonstrate that incorporation of 2′,5′-linked RNA in the gap region dramatically improved hepatotoxicity profile of PS-ASOs without compromising potency and provide a novel alternate chemical approach for improving therapeutic index of ASO drugs.",2026-06-07T02:20:35+00:00
31525,toxicity_endpoint,679,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"NVP-13 was very well tolerated, with “No Observed Adverse Effect Level” up to 4 mg/animal.",2026-06-07T02:20:35+00:00
31526,toxicity_endpoint,680,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"IONIS-AGT-LRx was well tolerated with no significant changes in platelet count, potassium levels, or liver and renal function.",2026-06-07T02:20:35+00:00
31527,toxicity_endpoint,681,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33567244; Reject: passage discusses SSO screening and future in vivo pharmacokinetic/toxicity evaluation, but does not report a primary administered/measured toxicity endpoint for the oligo.",2026-06-07T02:20:35+00:00
31528,toxicity_endpoint,682,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34648028; Reject: passage reports GalNAc-siRNA activity, off-target profile, and liver guide-strand levels, not an observed safety/toxicity/tolerability endpoint.",2026-06-07T02:20:35+00:00
31529,toxicity_endpoint,683,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32749923; Reject: the cytotoxicity statement concerns generic polymer-siRNA delivery/polyplex materials without a named therapeutic oligonucleotide candidate in scope.,2026-06-07T02:20:35+00:00
31530,toxicity_endpoint,684,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In vivo, it shows good biocompatibility as there are no changes in mice’s body weight.",2026-06-07T02:20:35+00:00
31531,toxicity_endpoint,685,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34681893; Reject: passage concerns ammonia-induced astrocyte/RNA toxicity biology and tool perturbation, not safety of an administered therapeutic oligonucleotide.",2026-06-07T02:20:35+00:00
31532,toxicity_endpoint,686,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No gross pathological findings related to the mRNA vaccine or CpG were observed in the liver (Figure 5M).,2026-06-07T02:20:35+00:00
31533,toxicity_endpoint,687,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In viability assays using MRCV-19 alone, we observed a high level of viability after cellular exposure to MRCV-19 at different concentrations (Figure 4). We observed low toxicity over 72 h post-exposure.",2026-06-07T02:20:35+00:00
31534,toxicity_endpoint,688,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34331779; Reject: ALT and inflammatory findings reflect diet-induced disease modulation by AAV/RNAi or GalNAc-Sab-ASO efficacy, not oligo-attributable toxicity/safety.",2026-06-07T02:20:35+00:00
31535,toxicity_endpoint,689,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34288499; Reject: the passage evaluates bis-morpholine triazine quaternary ammonium salts, not a therapeutic oligonucleotide or delivery product.",2026-06-07T02:20:35+00:00
31536,toxicity_endpoint,690,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,No differences in toxicity were observed between arms.,2026-06-07T02:20:35+00:00
31537,toxicity_endpoint,691,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33953843; Reject: passage concerns mibefradil small-molecule radiosensitizers and DDR knockdown assays, not therapeutic oligonucleotide toxicity.",2026-06-07T02:20:35+00:00
31538,toxicity_endpoint,692,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33742144; Reject: LDHA suppression is performed with shRNA/tool biology and efficacy framing; no therapeutic oligo safety endpoint is reported.,2026-06-07T02:20:35+00:00
31539,toxicity_endpoint,693,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Most of the R- and S-5′-methyl DNA modified ASOs exhibited comparable potency but significantly reduced toxicity even at the highest dose of 150 mg/kg, as compared to the parent ASO 558807 which can be lethal when administered at doses above 50 mg/kg (Figure 4A and B).",2026-06-07T02:20:35+00:00
31540,toxicity_endpoint,694,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Consistently, no morphological abnormality was found in kidney and liver (Fig 6C), indicating that PMO‐M does not cause any detectable toxicity.",2026-06-07T02:20:35+00:00
31541,toxicity_endpoint,695,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Body weight did not significantly change for any ASO candidate. X05134 (ALT: 64.9 U/l ± 21.0, AST: 108.9 ± 13.5), X07080 (ALT: 287.2 U/l ± 65.3, AST: 273.4 ± 101.3) and X07095 (ALT: 95.9 U/l ± 46.7, AST: 89.1 ± 21.8, Saline ALT: 9.9 ± 2.2, Saline AST: 28.2 ± 2.2) produced relevant liver enzyme elevations while X07070, X07085, X07091 = NVP-13 and X07065 did not affect ALT and AST levels compared to saline.",2026-06-07T02:20:35+00:00
31542,toxicity_endpoint,696,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Assessment of liver sections revealed randomly distributed necrosis in ∼10% of hepatocytes in two mice injected with LNAc/2′OMe18h.,2026-06-07T02:20:35+00:00
31543,toxicity_endpoint,697,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32356888; Reject: this is a review/mechanistic discussion of PS-ASO protein interactions, not a primary administered/measured toxicity result from the source passage.",2026-06-07T02:20:35+00:00
31544,toxicity_endpoint,698,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 31991801; Reject: passage discusses endogenous ALS/FTLD repeat RNA toxicity as disease biology, not an administered therapeutic oligonucleotide safety endpoint.",2026-06-07T02:20:35+00:00
31545,toxicity_endpoint,699,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35515636; Reject: passage is an environmental lead-ion electrode paper and contains no therapeutic oligonucleotide toxicity evidence.,2026-06-07T02:20:35+00:00
31546,toxicity_endpoint,700,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"MYC ASO Treatment Is Not Associated with Morbidity, Mortality, or Toxicity We did not observe any toxicity-related morbidity or mortality in the treatment or control groups.",2026-06-07T02:20:35+00:00
31547,toxicity_endpoint,701,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30622178; Reject: observed apoptosis/cytotoxicity is in melanoma tumor cells and functions as anticancer/on-target or nonspecific chemistry efficacy/toxicity, which the v2 toxicity contract excludes.",2026-06-07T02:20:35+00:00
31548,toxicity_endpoint,702,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In general, all 2′-F modified AOs did not show any significant cytotoxicity in comparison to the fully 2′-OMe-PS control (Fig. 6).",2026-06-07T02:20:35+00:00
31549,toxicity_endpoint,703,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"However, replacing even one PS-linkage at position 2 or 3 from the 5′-side of the DNA-gap with alkylphosphonates reduced or eliminated toxicity of several hepatotoxic gapmer ASOs.",2026-06-07T02:20:35+00:00
31550,toxicity_endpoint,704,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 31546749; Rejected: CL-4RNV616 cytotoxicity/apoptosis is intended cancer-cell-killing efficacy, not a safety/toxicity endpoint.",2026-06-07T02:20:35+00:00
31551,toxicity_endpoint,705,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Finally, a comprehensive blood chemistry panel showed no detectable changes at any time point, suggesting a systemic tolerability of Di-siRNA administration to the CNS (Supplementary Fig. 14). Overall, Di-siRNA injection in CSF was well tolerated in mice at the doses and time points tested.",2026-06-07T02:20:35+00:00
31552,toxicity_endpoint,706,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"There were no serious or severe nonserious adverse events observed in the study. The most common treatment-emergent adverse event in both cohorts was mild injection site reactions [6 (50.0%) subjects in SAD cohort and 16 (64.0%) subjects in MAD cohort experienced at least one, all receiving IONIS-PKKRx].",2026-06-07T02:20:35+00:00
31553,toxicity_endpoint,707,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32038525; Rejected: article is an E. coli copper bioreporter/environmental toxicology study, not therapeutic oligonucleotide toxicity.",2026-06-07T02:20:35+00:00
31554,toxicity_endpoint,708,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Serum AST and ALT levels significantly declined (Figure 6A) and there was no change in creatinine and urea (Figure 6B) in BMSP-PMO-GF-treated adult mdx mice compared to untreated age-matched mdx controls, indicating no liver and kidney toxicities.",2026-06-07T02:20:35+00:00
31555,toxicity_endpoint,709,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 31495875; Rejected: passage discusses toxic PS-ASO interaction/localization mechanisms and prior toxicity context, but the row lacks a primary administered/measured safety endpoint.",2026-06-07T02:20:35+00:00
31556,toxicity_endpoint,710,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30448197; the abstained record was checked at abstract level, but general safety/systemic safety/tolerability is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
31557,toxicity_endpoint,711,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30464402; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for unspecified ASO.",2026-06-07T02:20:35+00:00
31558,toxicity_endpoint,712,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 30388622; significant remains unsupported for general toxicity/toxicity after abstract-level review of 'Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Mon?'.,2026-06-07T02:20:35+00:00
31559,toxicity_endpoint,713,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29461800; significantly remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Antisense Inhibitors Retain Activity in Pulmonary Models of Burkholderia Infection.'.,2026-06-07T02:20:35+00:00
31560,toxicity_endpoint,714,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30195785; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31561,toxicity_endpoint,715,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29997223; available abstract is not enough to curate hepatic/hepatotoxicity for LNA ASO as a verified toxicity record.,2026-06-07T02:20:35+00:00
31562,toxicity_endpoint,716,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29282321; 'A mixed modality approach towards Xi reactivation for Rett syndrome and other X-linked disorde?' does not provide a sufficiently specific administered-oligo toxicity endpoint for CDKL5.,2026-06-07T02:20:35+00:00
31563,toxicity_endpoint,717,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Revusiran was generally well tolerated, with transient, mild to moderate injection site reactions the most common treatment-emergent adverse events.",2026-06-07T02:20:35+00:00
31564,toxicity_endpoint,718,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 30970855 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for single.,2026-06-07T02:20:35+00:00
31565,toxicity_endpoint,719,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28799823 abstract/title reviewed; no clear in-scope general safety/systemic safety/tolerability endpoint is grounded for single.,2026-06-07T02:20:35+00:00
31566,toxicity_endpoint,720,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29246291; simple remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Tween 85-Modified Low Molecular Weight PEI Enhances Exon-Skipping of Antisense Morpholino Olig?'.,2026-06-07T02:20:35+00:00
31567,toxicity_endpoint,721,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28742140 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for similar.,2026-06-07T02:20:35+00:00
31568,toxicity_endpoint,722,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28334749; available abstract is not enough to curate hepatic/hepatotoxicity for similar as a verified toxicity record.,2026-06-07T02:20:35+00:00
31569,toxicity_endpoint,723,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,There was no significant difference between MS2 and MS2KN/CpG-STAT3siRNA spheres in terms of cytotoxicity.,2026-06-07T02:20:35+00:00
31570,toxicity_endpoint,724,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28373570; available abstract is not enough to curate hepatic/hepatotoxicity for unspecified PMO as a verified toxicity record.,2026-06-07T02:20:35+00:00
31571,toxicity_endpoint,725,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28119399; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31572,toxicity_endpoint,726,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 27351681; no source passage or abstract wording gives a dependable toxicity call for significant.,2026-06-07T02:20:35+00:00
31573,toxicity_endpoint,727,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"All the recorded values confirmed the safety profile of LNA-i-miR-221 in monkeys, as shown by hematology, coagulation, liver and kidney parameters (see Supplementary Figure S5–S7).",2026-06-07T02:20:35+00:00
31574,toxicity_endpoint,728,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 27570789; Rejected: review article summarizing RNA therapeutics, not a primary observed oligonucleotide toxicity result.",2026-06-07T02:20:35+00:00
31575,toxicity_endpoint,729,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"There was no evidence of liver toxicity or muscle damage at all doses examined, as determined by monitoring serum alanine transaminase (ALT)/aspartate transaminase (AST) and muscle creatine phosphokinase, respectively (data not shown).",2026-06-07T02:20:35+00:00
31576,toxicity_endpoint,730,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 27655663; available abstract is not enough to curate hepatic/hepatotoxicity for similarly as a verified toxicity record.,2026-06-07T02:20:35+00:00
31577,toxicity_endpoint,731,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"FM10 had no significant cell toxicity, and RNA-seq analyses of FSHD and control myotubes revealed that FM10 down-regulated many transcriptional targets of DUX4, without overt off-target effects.",2026-06-07T02:20:35+00:00
31578,toxicity_endpoint,732,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 26878886; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31579,toxicity_endpoint,733,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26042553; Rejected: study concerns ASO self-assembly and uptake mechanisms; loaded passage does not report a primary toxicity/safety endpoint for the ASO product.,2026-06-07T02:20:35+00:00
31580,toxicity_endpoint,734,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 25350581; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31581,toxicity_endpoint,735,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24866718 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for signalling.,2026-06-07T02:20:35+00:00
31582,toxicity_endpoint,736,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Exposure to LNA-i-miR-221 did not cause any significant behavioral changes or weight loss in animals. Histology did not reveal any organ damage or pathologic changes in the liver, kidney or heart tissues of treated mice (data not shown), which indicates that the treatment was not toxic.",2026-06-07T02:20:35+00:00
31583,toxicity_endpoint,737,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 24506227; available abstract is not enough to curate hepatic/hepatotoxicity for significant as a verified toxicity record.,2026-06-07T02:20:35+00:00
31584,toxicity_endpoint,738,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 23982190; Rejected: loaded passage only provides AMO design/toxicity background and a broad no-toxicity claim, without a grounded primary measured toxicity endpoint.",2026-06-07T02:20:35+00:00
31585,toxicity_endpoint,739,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 21179007; significantly remains unsupported for general toxicity/toxicity after abstract-level review of 'One-year treatment of morpholino antisense oligomer improves skeletal and cardiac muscle funct?'.,2026-06-07T02:20:35+00:00
31586,toxicity_endpoint,740,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 20498851 abstract/title reviewed; no clear in-scope general safety/cell viability/cytotoxicity endpoint is grounded for silences.,2026-06-07T02:20:35+00:00
31587,toxicity_endpoint,741,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 20615897; 'Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and?' does not provide a sufficiently specific administered-oligo toxicity endpoint for sinus.,2026-06-07T02:20:35+00:00
31588,toxicity_endpoint,742,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,The Methylene-cLNA ASO D1 and the R-Me-cLNA ASO D2 showed modest to no elevations in ALT levels at the highest does evaluated while the LNA ASO was toxic at the high dose.,2026-06-07T02:20:35+00:00
31589,toxicity_endpoint,743,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for general safety/systemic safety/tolerability in single; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31590,toxicity_endpoint,744,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41711123 abstract/title reviewed; no clear in-scope general safety/systemic safety/tolerability endpoint is grounded for situ.,2026-06-07T02:20:35+00:00
31591,toxicity_endpoint,745,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42214258; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31592,toxicity_endpoint,746,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 42155236; previous accept was too weak/generic for hepatic/hepatotoxicity in silencing. Basis checked: Accepted: siRNA-loaded LNP formulation is linked in the abstract to an observed absence of detectable cytotoxicity in cells.,2026-06-07T02:20:35+00:00
31593,toxicity_endpoint,747,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42097228; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31594,toxicity_endpoint,748,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41411532; significant remains unsupported for general safety/cell viability/cytotoxicity after abstract-level review of 'Rational Design of Chimeric Antisense Oligonucleotides that Target FMN Riboswitch mRNAs and In?'.,2026-06-07T02:20:35+00:00
31595,toxicity_endpoint,749,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41936854; Rejected: shRNA is a screening/knockdown tool used to study valproic-acid hepatotoxicity; the toxic exposure is VPA, not an oligo therapeutic.",2026-06-07T02:20:35+00:00
31596,toxicity_endpoint,750,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41832714; no source passage or abstract wording gives a dependable toxicity call for siRNA-Loaded.,2026-06-07T02:20:35+00:00
31597,toxicity_endpoint,751,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41570670 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31598,toxicity_endpoint,752,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42037220; available abstract is not enough to curate general safety/cell viability/cytotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31599,toxicity_endpoint,753,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41644074; Rejected: reported cytotoxicity/apoptosis is squamous carcinoma antitumor efficacy of siRNA/5-FU nanoparticles, not product safety.",2026-06-07T02:20:35+00:00
31600,toxicity_endpoint,754,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for hepatic/hepatotoxicity in siRNA-micelles; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31601,toxicity_endpoint,755,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42191889 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA-mediated.,2026-06-07T02:20:35+00:00
31602,toxicity_endpoint,756,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42176919; no source passage or abstract wording gives a dependable toxicity call for silencing.,2026-06-07T02:20:35+00:00
31603,toxicity_endpoint,757,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42176843; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31604,toxicity_endpoint,758,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42143999; singleton remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'In vitro fertilization-associated osteomodulin upregulation is linked to impaired placental an?'.,2026-06-07T02:20:35+00:00
31605,toxicity_endpoint,759,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in signals; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31606,toxicity_endpoint,760,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42099136; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for unspecified ASO.",2026-06-07T02:20:35+00:00
31607,toxicity_endpoint,761,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42098773; silencing remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Tumor-targeted liposomal RNAi therapy suppresses breast cancer and modulates tumor microenviro?'.,2026-06-07T02:20:35+00:00
31608,toxicity_endpoint,762,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42076851; available abstract is not enough to curate hepatic/hepatotoxicity for Silver as a verified toxicity record.,2026-06-07T02:20:35+00:00
31609,toxicity_endpoint,763,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42067490; available abstract is not enough to curate hepatic/hepatotoxicity for unspecified ASO as a verified toxicity record.,2026-06-07T02:20:35+00:00
31610,toxicity_endpoint,764,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42060212; 'A patient-derived organoid model identifies TP53-dependent gemcitabine sensitivity in spinal c?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significant.,2026-06-07T02:20:35+00:00
31611,toxicity_endpoint,765,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42046304; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31612,toxicity_endpoint,766,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42007566; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for signaling.",2026-06-07T02:20:35+00:00
31613,toxicity_endpoint,767,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41996792; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31614,toxicity_endpoint,768,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41967235; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31615,toxicity_endpoint,769,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41962730; siRNAs remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Carrier-free spherical nucleic acids engineered by coordination-competition for programmable r?'.,2026-06-07T02:20:35+00:00
31616,toxicity_endpoint,770,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41956481; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31617,toxicity_endpoint,771,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41950730; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31618,toxicity_endpoint,772,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41932596; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
31619,toxicity_endpoint,773,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41932066; Single-cell remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Single-cell transcriptomics reveal PRRC1 as a malignant cell enriched driver of DNA repair and?'.,2026-06-07T02:20:35+00:00
31620,toxicity_endpoint,774,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41930872; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31621,toxicity_endpoint,775,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41876006; 'Securinine suppresses pancreatic cancer progression by activating the p38 MAPK pathway to upre?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significantly.,2026-06-07T02:20:35+00:00
31622,toxicity_endpoint,776,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41857757; available abstract is not enough to curate hepatic/hepatotoxicity for RAC1 as a verified toxicity record.,2026-06-07T02:20:35+00:00
31623,toxicity_endpoint,777,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41839309; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for simulations.",2026-06-07T02:20:35+00:00
31624,toxicity_endpoint,778,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41831864; available abstract is not enough to curate hepatic/hepatotoxicity for significant as a verified toxicity record.,2026-06-07T02:20:35+00:00
31625,toxicity_endpoint,779,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41831738; available abstract is not enough to curate hepatic/hepatotoxicity for SIRT1-regulated as a verified toxicity record.,2026-06-07T02:20:35+00:00
31626,toxicity_endpoint,780,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41821425; the abstained record was checked at abstract level, but general safety/systemic safety/tolerability is still not directly recoverable for tofersen.",2026-06-07T02:20:35+00:00
31627,toxicity_endpoint,781,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41818944; 'Huaier-derived arnicolide D induces ferroptosis in gastric cancer via SRC/TNF-mediated GPX4 in?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA-mediated.,2026-06-07T02:20:35+00:00
31628,toxicity_endpoint,782,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41806608; no source passage or abstract wording gives a dependable toxicity call for unspecified ASO.,2026-06-07T02:20:35+00:00
31629,toxicity_endpoint,783,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41775213; signaling remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Neveskin from Ferula samarcandica exerts anti-gastric cancer effects via the Hippo-YAP signali?'.,2026-06-07T02:20:35+00:00
31630,toxicity_endpoint,784,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41721069; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for unspecified ASO.",2026-06-07T02:20:35+00:00
31631,toxicity_endpoint,785,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41707964; '4-MEC potentially triggers CAV1 via the BDNF-TrkB signaling pathway.' does not provide a sufficiently specific administered-oligo toxicity endpoint for signaling.,2026-06-07T02:20:35+00:00
31632,toxicity_endpoint,786,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41617419; available abstract is not enough to curate hepatic/hepatotoxicity for side as a verified toxicity record.,2026-06-07T02:20:35+00:00
31633,toxicity_endpoint,787,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41582000; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for Hsc70-Bim.",2026-06-07T02:20:35+00:00
31634,toxicity_endpoint,788,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41564474 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31635,toxicity_endpoint,789,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41548790 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for significant.,2026-06-07T02:20:35+00:00
31636,toxicity_endpoint,790,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41548376; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
31637,toxicity_endpoint,791,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41492227; available abstract is not enough to curate hepatic/hepatotoxicity for silence as a verified toxicity record.,2026-06-07T02:20:35+00:00
31638,toxicity_endpoint,792,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41483378 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for signature.,2026-06-07T02:20:35+00:00
31639,toxicity_endpoint,793,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41470012; no source passage or abstract wording gives a dependable toxicity call for Silencers.,2026-06-07T02:20:35+00:00
31640,toxicity_endpoint,794,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41461321; the abstained record was checked at abstract level, but immunotoxicity/immune activation is still not directly recoverable for single-walled.",2026-06-07T02:20:35+00:00
31641,toxicity_endpoint,795,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41453580; available abstract is not enough to curate hepatic/hepatotoxicity for Rab3a-directed as a verified toxicity record.,2026-06-07T02:20:35+00:00
31642,toxicity_endpoint,796,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41422812; available abstract is not enough to curate hepatic/hepatotoxicity for sites as a verified toxicity record.,2026-06-07T02:20:35+00:00
31643,toxicity_endpoint,797,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41422761 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31644,toxicity_endpoint,798,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41418634; 'Ginsenoside F3 alleviates T cell exhaustion via RIPOR2-mediated immunometabolic reprogramming?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA.,2026-06-07T02:20:35+00:00
31645,toxicity_endpoint,799,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41360238; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for siMDR1.",2026-06-07T02:20:35+00:00
31646,toxicity_endpoint,800,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41351883; Rejected: agricultural termite RNAi/insecticide susceptibility study; not therapeutic oligonucleotide safety.,2026-06-07T02:20:35+00:00
31647,toxicity_endpoint,801,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41344487; no source passage or abstract wording gives a dependable toxicity call for simultaneously.,2026-06-07T02:20:35+00:00
31648,toxicity_endpoint,802,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41344272; 'Harmine inhibits non-small cell lung cancer growth by targeting phosphodiesterase4D and induci?' does not provide a sufficiently specific administered-oligo toxicity endpoint for signaling.,2026-06-07T02:20:35+00:00
31649,toxicity_endpoint,803,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41317784; 'NCOA4-mediated ferritinophagy regulates AgNP-induced ferroptosis in lung cells.' does not provide a sufficiently specific administered-oligo toxicity endpoint for Silver.,2026-06-07T02:20:35+00:00
31650,toxicity_endpoint,804,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41161393; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
31651,toxicity_endpoint,805,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41101550; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
31652,toxicity_endpoint,806,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject after curator re-read: PMID 40902370; previous accept was too weak/generic for hepatic/hepatotoxicity in silencing. Basis checked: Accepted: nucleic-acid AuNP delivery product is linked to an in vitro no-toxicity observation.,2026-06-07T02:20:35+00:00
31653,toxicity_endpoint,807,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41724477; 'The E3 ubiquitin ligase NEDD4 protects against nonesterified fatty acid-induced hepatic inflam?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significantly.,2026-06-07T02:20:35+00:00
31654,toxicity_endpoint,808,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41419139; available abstract is not enough to curate hepatic/hepatotoxicity for silenced as a verified toxicity record.,2026-06-07T02:20:35+00:00
31655,toxicity_endpoint,809,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41275931 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for simulate.,2026-06-07T02:20:35+00:00
31656,toxicity_endpoint,810,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42226100; 'Exendin-4 averts all-trans-retinal-driven damage to photoreceptors and the retina via the GLP-?' does not provide a sufficiently specific administered-oligo toxicity endpoint for signaling.,2026-06-07T02:20:35+00:00
31657,toxicity_endpoint,811,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40646322; 'The UBE3A-ATS antisense oligonucleotide rugonersen in children with Angelman syndrome: a phase?' does not provide a sufficiently specific administered-oligo toxicity endpoint for silenced.,2026-06-07T02:20:35+00:00
31658,toxicity_endpoint,812,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in single; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31659,toxicity_endpoint,813,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in inotersen; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31660,toxicity_endpoint,814,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40849139; no source passage or abstract wording gives a dependable toxicity call for sites.,2026-06-07T02:20:35+00:00
31661,toxicity_endpoint,815,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39882764; 'Characterizing Antisense Oligonucleotide-Induced Histopathology Findings in Spinal Cord of Mau?' does not provide a sufficiently specific administered-oligo toxicity endpoint for the ASO.,2026-06-07T02:20:35+00:00
31662,toxicity_endpoint,816,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40720030; no source passage or abstract wording gives a dependable toxicity call for Significant.,2026-06-07T02:20:35+00:00
31663,toxicity_endpoint,817,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41043736; 'Incorporation of monophosphoryl lipid A and CpG-oligodeoxynucleotides into lipid nanoparticles?' does not provide a sufficiently specific administered-oligo toxicity endpoint for signaling.,2026-06-07T02:20:35+00:00
31664,toxicity_endpoint,818,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40454845; available abstract is not enough to curate hepatic/hepatotoxicity for single as a verified toxicity record.,2026-06-07T02:20:35+00:00
31665,toxicity_endpoint,819,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for hepatic/hepatotoxicity in significant; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31666,toxicity_endpoint,820,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39960827; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for similar.",2026-06-07T02:20:35+00:00
31667,toxicity_endpoint,821,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41504091 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA-Mediated.,2026-06-07T02:20:35+00:00
31668,toxicity_endpoint,822,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40736725; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31669,toxicity_endpoint,823,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40907899 abstract/title reviewed; no clear in-scope general safety/cell viability/cytotoxicity endpoint is grounded for silk.,2026-06-07T02:20:35+00:00
31670,toxicity_endpoint,824,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40306576; the abstained record was checked at abstract level, but general safety/cell viability/cytotoxicity is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
31671,toxicity_endpoint,825,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40175880; 'A Robust Post-Insertion Method for the Preparation of Targeted Lipid Nanoparticles.' does not provide a sufficiently specific administered-oligo toxicity endpoint for significant.,2026-06-07T02:20:35+00:00
31672,toxicity_endpoint,826,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39878452 abstract/title reviewed; no clear in-scope general safety/cell viability/cytotoxicity endpoint is grounded for unspecified ASO.,2026-06-07T02:20:35+00:00
31673,toxicity_endpoint,827,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39855282; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31674,toxicity_endpoint,828,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39791575 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31675,toxicity_endpoint,829,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for hepatic/hepatotoxicity in siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31676,toxicity_endpoint,830,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for hepatic/hepatotoxicity in siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31677,toxicity_endpoint,831,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41249096; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31678,toxicity_endpoint,832,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41197701; the abstained record was checked at abstract level, but immunotoxicity/immune activation is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31679,toxicity_endpoint,833,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41194772; 'A Circular Aptamer-ASO Chimera for Activating DLX5-Regulated Osteogenesis through Targeted Inh?' does not provide a sufficiently specific administered-oligo toxicity endpoint for silencing.,2026-06-07T02:20:35+00:00
31680,toxicity_endpoint,834,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41124733; 'Nanoplastic-induced NAT10/ac4C axis drives both oxidative stress and chemoresistance.' does not provide a sufficiently specific administered-oligo toxicity endpoint for significant.,2026-06-07T02:20:35+00:00
31681,toxicity_endpoint,835,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41086675; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for SIRT4.",2026-06-07T02:20:35+00:00
31682,toxicity_endpoint,836,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41046827; no source passage or abstract wording gives a dependable toxicity call for SiRNA-mediated.,2026-06-07T02:20:35+00:00
31683,toxicity_endpoint,837,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40846040; available abstract is not enough to curate hepatic/hepatotoxicity for significant as a verified toxicity record.,2026-06-07T02:20:35+00:00
31684,toxicity_endpoint,838,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40845764; 'SQSTM1/p62 drives radiosensitivity in cervical cancer via autophagy-independent mechanisms.' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA-mediated.,2026-06-07T02:20:35+00:00
31685,toxicity_endpoint,839,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40816462; significant remains unsupported for general toxicity/toxicity after abstract-level review of 'The effect and mechanism of NCOA4-mediated ferritinophagy in aluminum-induced ferroptosis of P?'.,2026-06-07T02:20:35+00:00
31686,toxicity_endpoint,840,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40720029; available abstract is not enough to curate hepatic/hepatotoxicity for significant as a verified toxicity record.,2026-06-07T02:20:35+00:00
31687,toxicity_endpoint,841,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40694678 abstract/title reviewed; no clear in-scope renal/renal safety endpoint is grounded for Signaling.,2026-06-07T02:20:35+00:00
31688,toxicity_endpoint,842,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40685728; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31689,toxicity_endpoint,843,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40682728; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31690,toxicity_endpoint,844,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40680668; available abstract is not enough to curate hepatic/hepatotoxicity for significantly as a verified toxicity record.,2026-06-07T02:20:35+00:00
31691,toxicity_endpoint,845,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40663327; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for unspecified ASO.",2026-06-07T02:20:35+00:00
31692,toxicity_endpoint,846,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40641021; 'Nanocarriers in Atopic Dermatitis Therapy: A Comprehensive Exploration.' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA-silenced.,2026-06-07T02:20:35+00:00
31693,toxicity_endpoint,847,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40624770 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for significantly.,2026-06-07T02:20:35+00:00
31694,toxicity_endpoint,848,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40544907; 'Regulation of ferroptosis ameliorates silica nanoparticle-induced lung injury by inhibiting NC?' does not provide a sufficiently specific administered-oligo toxicity endpoint for silica.,2026-06-07T02:20:35+00:00
31695,toxicity_endpoint,849,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40484286; Rejected: lipid-siRNA system is an assay/screening tool in adult sensory neurons, not a therapeutic oligonucleotide toxicity result.",2026-06-07T02:20:35+00:00
31696,toxicity_endpoint,850,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40456202; 'Ponicidin triggered ferroptosis in esophageal squamous cell carcinoma by suppressing the SLC7A?' does not provide a sufficiently specific administered-oligo toxicity endpoint for signalling.,2026-06-07T02:20:35+00:00
31697,toxicity_endpoint,851,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40450984; siRNA-mediated remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Jianpi Huayu decoction enhances the antitumor effect of doxorubicin via piezo1-mediated autoph?'.,2026-06-07T02:20:35+00:00
31698,toxicity_endpoint,852,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40327939; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for signaling.",2026-06-07T02:20:35+00:00
31699,toxicity_endpoint,853,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40286451 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for signaling.,2026-06-07T02:20:35+00:00
31700,toxicity_endpoint,854,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40222106; no source passage or abstract wording gives a dependable toxicity call for signaling.,2026-06-07T02:20:35+00:00
31701,toxicity_endpoint,855,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40220706; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31702,toxicity_endpoint,856,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40202160; signalling remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Human circulatory proteome interaction, oxidative stress-associated signalling and cardiovascu?'.",2026-06-07T02:20:35+00:00
31703,toxicity_endpoint,857,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40190139; 'Xanthohumol Regulates Mitophagy in Osteosarcoma Cells via AMPK-ULK1-FUNDC1 Signaling Pathway.' does not provide a sufficiently specific administered-oligo toxicity endpoint for Signaling.,2026-06-07T02:20:35+00:00
31704,toxicity_endpoint,858,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40184263; site remains unsupported for renal/renal safety after abstract-level review of 'Contribution of Nilaparvata lugens Nicotinic Acetylcholine Receptor Subunits Toward Triflumezo?'.,2026-06-07T02:20:35+00:00
31705,toxicity_endpoint,859,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40112899; sites remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Inhalable pH-responsive charge-reversal polymer-small interfering RNA polyplexes for directed?'.,2026-06-07T02:20:35+00:00
31706,toxicity_endpoint,860,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40049439; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
31707,toxicity_endpoint,861,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39964965; no source passage or abstract wording gives a dependable toxicity call for silencing.,2026-06-07T02:20:35+00:00
31708,toxicity_endpoint,862,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39904427; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31709,toxicity_endpoint,863,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39827759; Rejected: cytotoxicity refers to doxorubicin antitumor efficacy/chemoresistance; no primary safety endpoint for the siRNA nanoparticle is reported.,2026-06-07T02:20:35+00:00
31710,toxicity_endpoint,864,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39820813; 'Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunot?' does not provide a sufficiently specific administered-oligo toxicity endpoint for silencing.,2026-06-07T02:20:35+00:00
31711,toxicity_endpoint,865,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39809473; single remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'MRI-Based Multifunctional Nanoliposomes for Enhanced HCC Therapy and Diagnosis.'.,2026-06-07T02:20:35+00:00
31712,toxicity_endpoint,866,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39661279; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Cell Type-Preferential Expression of Peptidylarginine Deiminase 4 and p53-Dependent Therapeuti?'.,2026-06-07T02:20:35+00:00
31713,toxicity_endpoint,867,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39586487; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for signal.",2026-06-07T02:20:35+00:00
31714,toxicity_endpoint,868,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39580141; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31715,toxicity_endpoint,869,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40886138; 'A Novel PROTAC G9a/GLP Degrader that Inhibits, Similar to G9a siRNA, the Migration of MCF-7 Br?' does not provide a sufficiently specific administered-oligo toxicity endpoint for Similar.",2026-06-07T02:20:35+00:00
31716,toxicity_endpoint,870,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39835559; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'siRNA Knocking Down in HepG2 Cells Identifies PFKFB4 and HNF4α as Key Genes Important for Canc?'.,2026-06-07T02:20:35+00:00
31717,toxicity_endpoint,871,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39630486 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31718,toxicity_endpoint,872,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40403679; 'Senkyunolide A mitigates lipid deposition in hyperlipidemic hepatocytes through SIRT6-mediated?' does not provide a sufficiently specific administered-oligo toxicity endpoint for SIRT6-mediated.,2026-06-07T02:20:35+00:00
31719,toxicity_endpoint,873,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40015535; significantly remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Effect of Sceptridium ternatum extract (STE) on radiation-induced pulmonary fibrosis by inhibi?'.,2026-06-07T02:20:35+00:00
31720,toxicity_endpoint,874,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40012358; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Discovery of Novel Oxazolo[4,3-f]purine Derivatives as Antitumor Agents through PPIA Interacti?'.",2026-06-07T02:20:35+00:00
31721,toxicity_endpoint,875,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39947390; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Esketamine mitigates endotoxin-induced hippocampal injury by regulating calcium transient and?'.,2026-06-07T02:20:35+00:00
31722,toxicity_endpoint,876,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39844419; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Resveratrol Reduces Cisplatin-induced Cochlear Hair Cell Pyroptosis by Inhibiting the mtROS/TX?'.,2026-06-07T02:20:35+00:00
31723,toxicity_endpoint,877,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39700772; signaling remains unsupported for immunotoxicity/immune activation after abstract-level review of 'Rutin attenuates zearalenone-induced ferroptosis of endometrial stromal cells in piglets throu?'.,2026-06-07T02:20:35+00:00
31724,toxicity_endpoint,878,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38155279; available abstract is not enough to curate renal/renal safety for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31725,toxicity_endpoint,879,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38040383; available abstract is not enough to curate general toxicity/toxicity for site as a verified toxicity record.,2026-06-07T02:20:35+00:00
31726,toxicity_endpoint,880,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38945909; inclisiran remains unsupported for immunotoxicity/immune activation after abstract-level review of '[Pharmacological and clinical profile of inclisiran sodium, a long-acting LDL cholesterol lowe?'.",2026-06-07T02:20:35+00:00
31727,toxicity_endpoint,881,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38688053 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for simulation.,2026-06-07T02:20:35+00:00
31728,toxicity_endpoint,882,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38330721; 'Repurposing sodium stibogluconate as an uracil DNA glycosylase inhibitor against prostate canc?' does not provide a sufficiently specific administered-oligo toxicity endpoint for unspecified ASO.,2026-06-07T02:20:35+00:00
31729,toxicity_endpoint,883,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39321527; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for signaling.",2026-06-07T02:20:35+00:00
31730,toxicity_endpoint,884,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39245217 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for signaling.,2026-06-07T02:20:35+00:00
31731,toxicity_endpoint,885,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39136161; 'Unravelling the mechanism of apoptosis induced by copper(II) complexes of NN(2)-pincer ligands?' does not provide a sufficiently specific administered-oligo toxicity endpoint for silico.,2026-06-07T02:20:35+00:00
31732,toxicity_endpoint,886,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39101472; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for inclisiran.",2026-06-07T02:20:35+00:00
31733,toxicity_endpoint,887,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39008248; no source passage or abstract wording gives a dependable toxicity call for situ.,2026-06-07T02:20:35+00:00
31734,toxicity_endpoint,888,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38968904 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for multifunctional ASO.,2026-06-07T02:20:35+00:00
31735,toxicity_endpoint,889,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38795878; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for silico.",2026-06-07T02:20:35+00:00
31736,toxicity_endpoint,890,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38568291; 'Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiqui?' does not provide a sufficiently specific administered-oligo toxicity endpoint for similarly.,2026-06-07T02:20:35+00:00
31737,toxicity_endpoint,891,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38545650 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for similar.,2026-06-07T02:20:35+00:00
31738,toxicity_endpoint,892,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38465810; nusinersen remains unsupported for hepatic/hepatotoxicity after abstract-level review of '[Risdiplam for the treatment of spinal muscular atrophy].'.,2026-06-07T02:20:35+00:00
31739,toxicity_endpoint,893,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38442139 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31740,toxicity_endpoint,894,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38407513; no source passage or abstract wording gives a dependable toxicity call for Siderophore.,2026-06-07T02:20:35+00:00
31741,toxicity_endpoint,895,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38310055; 'Suppression of SOCS3 expression in macrophage cells: Potential application in diabetic wound h?' does not provide a sufficiently specific administered-oligo toxicity endpoint for Signaling.,2026-06-07T02:20:35+00:00
31742,toxicity_endpoint,896,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38220483; inclisiran remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'First Report of Inclisiran Utilization for Hypercholesterolemia Treatment in Real-world Clinic?'.,2026-06-07T02:20:35+00:00
31743,toxicity_endpoint,897,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37951450; 'Design, synthesis and anticancer evaluation of novel arylhydrazones of active methylene compou?' does not provide a sufficiently specific administered-oligo toxicity endpoint for signaling.",2026-06-07T02:20:35+00:00
31744,toxicity_endpoint,898,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39490472 abstract/title reviewed; no clear in-scope general safety/cell viability/cytotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31745,toxicity_endpoint,899,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39141571 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for sized.,2026-06-07T02:20:35+00:00
31746,toxicity_endpoint,900,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39547060; siRNA-MANF remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'MANF inhibits NLRP3 inflammasome activation by competitively binding to DDX3X in paraquat-stim?'.,2026-06-07T02:20:35+00:00
31747,toxicity_endpoint,901,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38961849; Rejected: R8HNP-siRNA is used as a stem-cell differentiation/gene-silencing protocol, not an administered therapeutic oligonucleotide safety result.",2026-06-07T02:20:35+00:00
31748,toxicity_endpoint,902,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37804762; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31749,toxicity_endpoint,903,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31750,toxicity_endpoint,904,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36228827; available abstract is not enough to curate renal/renal safety for inotersen as a verified toxicity record.,2026-06-07T02:20:35+00:00
31751,toxicity_endpoint,905,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in single; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31752,toxicity_endpoint,906,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36373781; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31753,toxicity_endpoint,907,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37962485; 'A Convenient Method for the Synthesis of 2'-O-Cyanoethylated Nucleotides and Their Application?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA.,2026-06-07T02:20:35+00:00
31754,toxicity_endpoint,908,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37769581; 'Identification of the Kupffer cell-derived circulating IGFBP-3 as a universal radiation biomar?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significant.,2026-06-07T02:20:35+00:00
31755,toxicity_endpoint,909,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in single-dose; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31756,toxicity_endpoint,910,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37458103; signs remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Cobalt bis(dicarbollide) is a DNA-neutral pharmacophore.'.,2026-06-07T02:20:35+00:00
31757,toxicity_endpoint,911,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37635089; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for of ASO.",2026-06-07T02:20:35+00:00
31758,toxicity_endpoint,912,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37059380 abstract/title reviewed; no clear in-scope general safety/cell viability/cytotoxicity endpoint is grounded for significant.,2026-06-07T02:20:35+00:00
31759,toxicity_endpoint,913,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36813076; siRNA-Bckdhb remains unsupported for renal/renal safety after abstract-level review of 'Effect of sevoflurane anesthesia to neonatal rat hippocampus by RNA-seq.'.,2026-06-07T02:20:35+00:00
31760,toxicity_endpoint,914,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36709649; 'Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacte?' does not provide a sufficiently specific administered-oligo toxicity endpoint for unspecified PMO.,2026-06-07T02:20:35+00:00
31761,toxicity_endpoint,915,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36608275; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for unspecified ASO.",2026-06-07T02:20:35+00:00
31762,toxicity_endpoint,916,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36401026; no source passage or abstract wording gives a dependable toxicity call for Since.,2026-06-07T02:20:35+00:00
31763,toxicity_endpoint,917,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36306888 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for signaling.,2026-06-07T02:20:35+00:00
31764,toxicity_endpoint,918,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35027752; siRNA remains unsupported for general safety/systemic safety/tolerability after abstract-level review of 'Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a).'.,2026-06-07T02:20:35+00:00
31765,toxicity_endpoint,919,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35042440; single remains unsupported for general safety/systemic safety/tolerability after abstract-level review of 'Antisense Oligonucleotide-Related Macrovesicular Vacuolation of Hippocampal Neurons in Nonhuma?'.,2026-06-07T02:20:35+00:00
31766,toxicity_endpoint,920,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34921096; Rejected: ASO unbound-fraction/protein-binding method has only potential-toxicity relevance, not an observed safety/toxicity endpoint.",2026-06-07T02:20:35+00:00
31767,toxicity_endpoint,921,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35749736; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Aggregation-Induced Emission (AIE) and Magnetic Resonance Imaging Characteristics for Targeted?'.,2026-06-07T02:20:35+00:00
31768,toxicity_endpoint,922,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36085230; available abstract is not enough to curate hepatic/hepatotoxicity for sites as a verified toxicity record.,2026-06-07T02:20:35+00:00
31769,toxicity_endpoint,923,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35189260; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31770,toxicity_endpoint,924,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35168151; available abstract is not enough to curate hepatic/hepatotoxicity for sidechain as a verified toxicity record.,2026-06-07T02:20:35+00:00
31771,toxicity_endpoint,925,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34915704; significantly remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Structural Modifications to the Internal Oligoguanidinium Transporter Uncover Two Potent Analo?'.,2026-06-07T02:20:35+00:00
31772,toxicity_endpoint,926,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34799047; available abstract is not enough to curate hepatic/hepatotoxicity for situ as a verified toxicity record.,2026-06-07T02:20:35+00:00
31773,toxicity_endpoint,927,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34101472; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
31774,toxicity_endpoint,928,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34474856; size remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Folate targeted hybrid lipo-polymeric nanoplexes containing docetaxel and miRNA-34a for breast?'.,2026-06-07T02:20:35+00:00
31775,toxicity_endpoint,929,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34062235; no source passage or abstract wording gives a dependable toxicity call for siRNAs.,2026-06-07T02:20:35+00:00
31776,toxicity_endpoint,930,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32599652; the abstained record was checked at abstract level, but general safety/systemic safety/tolerability is still not directly recoverable for vutrisiran.",2026-06-07T02:20:35+00:00
31777,toxicity_endpoint,931,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32865788; available abstract is not enough to curate general safety/cell viability/cytotoxicity for simple as a verified toxicity record.,2026-06-07T02:20:35+00:00
31778,toxicity_endpoint,932,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32330214; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for simultaneously.",2026-06-07T02:20:35+00:00
31779,toxicity_endpoint,933,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32726663; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31780,toxicity_endpoint,934,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32597264; no source passage or abstract wording gives a dependable toxicity call for significant.,2026-06-07T02:20:35+00:00
31781,toxicity_endpoint,935,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32857010 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for unspecified ASO.,2026-06-07T02:20:35+00:00
31782,toxicity_endpoint,936,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31812480; no source passage or abstract wording gives a dependable toxicity call for situ.,2026-06-07T02:20:35+00:00
31783,toxicity_endpoint,937,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31009315 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for which ASO.,2026-06-07T02:20:35+00:00
31784,toxicity_endpoint,938,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 30284504; 'Structural insight into antisense gapmer-RNA oligomer duplexes through molecular dynamics simu?' does not provide a sufficiently specific administered-oligo toxicity endpoint for simulations.,2026-06-07T02:20:35+00:00
31785,toxicity_endpoint,939,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31556592; Silencing remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Synthetic α-l-Threose Nucleic Acids Targeting BcL-2 Show Gene Silencing and in Vivo Antitumor?'.,2026-06-07T02:20:35+00:00
31786,toxicity_endpoint,940,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31036929 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for PS-ASO.,2026-06-07T02:20:35+00:00
31787,toxicity_endpoint,941,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30552932; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for signaling.",2026-06-07T02:20:35+00:00
31788,toxicity_endpoint,942,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30171554; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31789,toxicity_endpoint,943,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 29875202; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for CP05.",2026-06-07T02:20:35+00:00
31790,toxicity_endpoint,944,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28610721; available abstract is not enough to curate hepatic/hepatotoxicity for unspecified ASO as a verified toxicity record.,2026-06-07T02:20:35+00:00
31791,toxicity_endpoint,945,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 28571947; 'Boron nitride nanotubes for gene silencing.' does not provide a sufficiently specific administered-oligo toxicity endpoint for silencing.,2026-06-07T02:20:35+00:00
31792,toxicity_endpoint,946,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 27557584; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
31793,toxicity_endpoint,947,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In toxicity analysis, some of the linkers induced lethal toxicities when they were injected at high concentrations (>600μM). These toxicities were attributed to decreased platelet levels in the blood, suggesting an interaction between cholesterol-conjugated ASO and platelets.",2026-06-07T02:20:35+00:00
31794,toxicity_endpoint,948,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 26944796; the abstained record was checked at abstract level, but renal/renal safety is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
31795,toxicity_endpoint,949,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 27420413; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for unspecified ASO.",2026-06-07T02:20:35+00:00
31796,toxicity_endpoint,950,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in nusinersen; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31797,toxicity_endpoint,951,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 25197025; 'First proof of pharmacology in humans of a novel glucagon receptor antisense drug.' does not provide a sufficiently specific administered-oligo toxicity endpoint for single.,2026-06-07T02:20:35+00:00
31798,toxicity_endpoint,952,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for general safety/cell viability/cytotoxicity in AMO122; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31799,toxicity_endpoint,953,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 24085767; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for unspecified ASO.",2026-06-07T02:20:35+00:00
31800,toxicity_endpoint,954,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22149555 abstract/title reviewed; no clear in-scope general safety/systemic safety/tolerability endpoint is grounded for significantly.,2026-06-07T02:20:35+00:00
31801,toxicity_endpoint,955,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 19533419; no source passage or abstract wording gives a dependable toxicity call for site.,2026-06-07T02:20:35+00:00
31802,toxicity_endpoint,956,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41624332; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for two ASO.",2026-06-07T02:20:35+00:00
31803,toxicity_endpoint,957,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41388232; siRNA remains unsupported for general toxicity/toxicity after abstract-level review of 'Platform Assessment of Concentration-QTc Relationship Across GalNAc-siRNA Molecules.'.,2026-06-07T02:20:35+00:00
31804,toxicity_endpoint,958,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"A single 25 mg/kg pulmonary dose was safe and well-tolerated, with no adverse structural or immune effects.",2026-06-07T02:20:35+00:00
31805,toxicity_endpoint,959,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41994867; siDUX4 remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Development of a DUX4-targeting antibody oligonucleotide conjugate as a therapy for FSHD.'.,2026-06-07T02:20:35+00:00
31806,toxicity_endpoint,960,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41683454; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31807,toxicity_endpoint,961,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41856548; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for unspecified ASO.",2026-06-07T02:20:35+00:00
31808,toxicity_endpoint,962,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42041567; Reject: Atxn2-CAG100-knockin is a disease mouse model/transcriptomics study, not an administered therapeutic oligo toxicity endpoint.",2026-06-07T02:20:35+00:00
31809,toxicity_endpoint,963,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42033217; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
31810,toxicity_endpoint,964,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41867745; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31811,toxicity_endpoint,965,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41592789; 'Heteroduplex oligonucleotide technology boosts gene knockdown in cardiac and skeletal muscles.' does not provide a sufficiently specific administered-oligo toxicity endpoint for unconjugated ASO.,2026-06-07T02:20:35+00:00
31812,toxicity_endpoint,966,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Biochemical markers for liver functions, including alanine transaminase (ALT), aspartate aminotransferase (AST), albumin (ALB), and total bilirubin (TBIL), as well as indicators for cardiac and kidney injuries, such as lactate dehydrogenase (LDH) and serum creatinine (CREA) and blood urea nitrogen (BUN), showed no significant differences among all groups (Figure S6A, Supporting Information).",2026-06-07T02:20:35+00:00
31813,toxicity_endpoint,967,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41932914; Reject: FXR1 LNA-siRNA effects are cancer efficacy endpoints such as tumor growth, proliferation, apoptosis, and immune microenvironment, not oligo safety/toxicity.",2026-06-07T02:20:35+00:00
31814,toxicity_endpoint,968,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41754920 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for nusinersen.,2026-06-07T02:20:35+00:00
31815,toxicity_endpoint,969,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Both ASOs demonstrated potent, concentration-dependent gene silencing with IC50 values in the picomolar to low-nanomolar range for at least 48 h post-transfection, with no cytotoxicity at therapeutic concentrations (Figures 3 and 4).",2026-06-07T02:20:35+00:00
31816,toxicity_endpoint,970,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41673867; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31817,toxicity_endpoint,971,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41624166; Reject: siSaa2 is used therapeutically, but the cited endpoints are placental injury/preterm-birth efficacy under maternal inflammation, not safety or toxicity of the oligo product.",2026-06-07T02:20:35+00:00
31818,toxicity_endpoint,972,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41595780; the abstained record was checked at abstract level, but general toxicity/toxicity is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
31819,toxicity_endpoint,973,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41575989 abstract/title reviewed; no clear in-scope general safety/cell viability/cytotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31820,toxicity_endpoint,974,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"No significant toxicity of SNA-modified siRNA, including defective mouse behavior or weight gain, or histological signs of neuroinflammation was evident in the SBMA and SCA3 mice, supporting the safety and tolerability of this CNS treatment.",2026-06-07T02:20:35+00:00
31821,toxicity_endpoint,975,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41178597 abstract/title reviewed; no clear in-scope general toxicity/toxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31822,toxicity_endpoint,976,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40266550; available abstract is not enough to curate hepatic/hepatotoxicity for silver-based as a verified toxicity record.,2026-06-07T02:20:35+00:00
31823,toxicity_endpoint,977,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42206237; Reject: semaglutide is a small-molecule/peptide drug study with signaling and ferroptosis endpoints, not therapeutic oligo toxicity.",2026-06-07T02:20:35+00:00
31824,toxicity_endpoint,978,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42191816; available abstract is not enough to curate general toxicity/toxicity for site as a verified toxicity record.,2026-06-07T02:20:35+00:00
31825,toxicity_endpoint,979,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42182299; 'Impaired SOX17 Expression Causes Endothelial Dysfunction and Pulmonary Arterial Hypertension b?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA.,2026-06-07T02:20:35+00:00
31826,toxicity_endpoint,980,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42180769; available abstract is not enough to curate hepatic/hepatotoxicity for sizes as a verified toxicity record.,2026-06-07T02:20:35+00:00
31827,toxicity_endpoint,981,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42170640; available abstract is not enough to curate hepatic/hepatotoxicity for SIRT2 as a verified toxicity record.,2026-06-07T02:20:35+00:00
31828,toxicity_endpoint,982,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42164756; Reject: review article summarizes RNA-targeted therapeutics and toxicology elsewhere; no primary observed/administered toxicity result in this passage.,2026-06-07T02:20:35+00:00
31829,toxicity_endpoint,983,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42092277; available abstract is not enough to curate hepatic/hepatotoxicity for Similarly as a verified toxicity record.,2026-06-07T02:20:35+00:00
31830,toxicity_endpoint,984,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42087285; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31831,toxicity_endpoint,985,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42066623; Reject: siRNAs are experimental knockdown tools in ischemic stroke/mechanism work; toxicity language concerns disease injury or methods, not oligo safety.",2026-06-07T02:20:35+00:00
31832,toxicity_endpoint,986,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42038028; Reject: MUC16 siRNAs are cancer-cell knockdown tools and endpoints are anoikis/proliferation/metastatic efficacy, not oligo toxicity.",2026-06-07T02:20:35+00:00
31833,toxicity_endpoint,987,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42036047; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31834,toxicity_endpoint,988,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42007129; no source passage or abstract wording gives a dependable toxicity call for site-1.,2026-06-07T02:20:35+00:00
31835,toxicity_endpoint,989,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42003915; Reject: siRNA is used as a mechanistic cancer knockdown tool; endpoints are EMT/invasion/tumor biology, not safety/toxicity of an oligo product.",2026-06-07T02:20:35+00:00
31836,toxicity_endpoint,990,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41994627; Reject: FH535 is a small-molecule Wnt inhibitor and cited endpoints are colorectal cancer efficacy/immunomodulation, not therapeutic oligo toxicity.",2026-06-07T02:20:35+00:00
31837,toxicity_endpoint,991,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41993628; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for silencing.",2026-06-07T02:20:35+00:00
31838,toxicity_endpoint,992,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41987897; Reject: nc886 is an endogenous noncoding RNA/HBV mechanism study, not an administered therapeutic oligo safety endpoint.",2026-06-07T02:20:35+00:00
31839,toxicity_endpoint,993,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41986321; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
31840,toxicity_endpoint,994,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41968320; significant remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Loss of protein phosphatase 1 regulator TIMAP protein triggers EMT in A549 cells.'.,2026-06-07T02:20:35+00:00
31841,toxicity_endpoint,995,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41959481 abstract/title reviewed; no clear in-scope general safety/cell viability/cytotoxicity endpoint is grounded for siRNA-based.,2026-06-07T02:20:35+00:00
31842,toxicity_endpoint,996,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41913229; Reject: passage uses AAV/virus-drug conjugate and cancer cytotoxicity/transduction optimization; AAV/shRNA-style delivery and cancer-cell killing efficacy are excluded.,2026-06-07T02:20:35+00:00
31843,toxicity_endpoint,997,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41911534; 'Combination mRNA Vaccine Adjuvanted with CpG Oligodeoxynucleotides Enhances Protection against?' does not provide a sufficiently specific administered-oligo toxicity endpoint for unspecified CpG oligodeoxynucleotide.,2026-06-07T02:20:35+00:00
31844,toxicity_endpoint,998,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41909465; Reject: AdV-shTIPE2 is an adenoviral shRNA knockdown strategy and endpoints are DSS colitis efficacy/disease-injury measures, not oligo toxicity.",2026-06-07T02:20:35+00:00
31845,toxicity_endpoint,999,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41889731 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for significantly.,2026-06-07T02:20:35+00:00
31846,toxicity_endpoint,1000,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41884417; Reject: siRNA knockdown is an in vitro breast-cancer target-validation tool; cell proliferation/migration endpoints are efficacy, not oligo toxicity.",2026-06-07T02:20:35+00:00
31847,toxicity_endpoint,1001,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41883862; Reject: MSR1 siRNA/silencing is a mechanistic macrophage tool in lupus nephritis signaling, not administered oligo safety/toxicity.",2026-06-07T02:20:35+00:00
31848,toxicity_endpoint,1002,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41882730 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for situ.,2026-06-07T02:20:35+00:00
31849,toxicity_endpoint,1003,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41862802 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for CD36.,2026-06-07T02:20:35+00:00
31850,toxicity_endpoint,1004,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41820988 abstract/title reviewed; no clear in-scope general safety/cell viability/cytotoxicity endpoint is grounded for signaling.,2026-06-07T02:20:35+00:00
31851,toxicity_endpoint,1005,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41814308 abstract/title reviewed; no clear in-scope general safety/cell viability/cytotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31852,toxicity_endpoint,1006,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41808881; available abstract is not enough to curate general toxicity/toxicity for unspecified siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31853,toxicity_endpoint,1007,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41787499; Reject: single-cell/spatial transcriptomics and shRNA-mediated WTAP silencing in fibrosis are mechanism/efficacy studies, not therapeutic oligo toxicity.",2026-06-07T02:20:35+00:00
31854,toxicity_endpoint,1008,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41749901; Reject: ERCC8/CSA antisense use is melanoma efficacy sensitization; normal-cell sparing/cell death is cancer therapy efficacy, not oligo toxicity.",2026-06-07T02:20:35+00:00
31855,toxicity_endpoint,1009,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41730837; Reject: SiHa is a cervical cancer cell line and siRNA is a gene-expression tool; no therapeutic oligo safety/tolerability endpoint.,2026-06-07T02:20:35+00:00
31856,toxicity_endpoint,1010,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41717287; Reject: tau artificial microRNAs are delivered by viral vectors and endpoints are functional recovery/efficacy; viral/amiRNA tool strategy is excluded.,2026-06-07T02:20:35+00:00
31857,toxicity_endpoint,1011,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41706894; siRNA-based remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Lamin B receptor upregulation in metastatic melanoma causes nuclear envelope fragility in conf?'.,2026-06-07T02:20:35+00:00
31858,toxicity_endpoint,1012,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41676641; no source passage or abstract wording gives a dependable toxicity call for ARS2.,2026-06-07T02:20:35+00:00
31859,toxicity_endpoint,1013,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41674969; Reject: siRNA-mediated VDAC knockdown is HCC cell target validation; apoptosis/ferroptosis/proliferation endpoints are cancer efficacy, not safety.",2026-06-07T02:20:35+00:00
31860,toxicity_endpoint,1014,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41670738; available abstract is not enough to curate hepatic/hepatotoxicity for tofersen as a verified toxicity record.,2026-06-07T02:20:35+00:00
31861,toxicity_endpoint,1015,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41603250 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for Signaling.,2026-06-07T02:20:35+00:00
31862,toxicity_endpoint,1016,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41588921; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31863,toxicity_endpoint,1017,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41564859; no source passage or abstract wording gives a dependable toxicity call for size.,2026-06-07T02:20:35+00:00
31864,toxicity_endpoint,1018,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41559666; Reject: melanoma siRNA knockdown of TMX4 is target-validation/cancer phenotype work; proliferation, migration, and redox endpoints are not oligo toxicity.",2026-06-07T02:20:35+00:00
31865,toxicity_endpoint,1019,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41433111; the abstained record was checked at abstract level, but renal/renal safety is still not directly recoverable for Signaling.",2026-06-07T02:20:35+00:00
31866,toxicity_endpoint,1020,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41358055; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31867,toxicity_endpoint,1021,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41199675; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
31868,toxicity_endpoint,1022,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41076566; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31869,toxicity_endpoint,1023,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41823075; available abstract is not enough to curate hepatic/hepatotoxicity for significantly as a verified toxicity record.,2026-06-07T02:20:35+00:00
31870,toxicity_endpoint,1024,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41810963; no source passage or abstract wording gives a dependable toxicity call for silence.,2026-06-07T02:20:35+00:00
31871,toxicity_endpoint,1025,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41792108; Rejected: C1s siRNA/CRISPR perturbation is a mechanistic cancer apoptosis study and TRAIL sensitization is cancer-cell-killing efficacy, not therapeutic oligo toxicity.",2026-06-07T02:20:35+00:00
31872,toxicity_endpoint,1026,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41768995; Rejected: TrpC5 siRNA is used to modulate papillary thyroid carcinoma proliferation/radiosensitivity; apoptosis and DNA damage are anticancer efficacy endpoints.,2026-06-07T02:20:35+00:00
31873,toxicity_endpoint,1027,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41751842; Signaling remains unsupported for general toxicity/toxicity after abstract-level review of 'COPG1 Is a Selectively Essential Regulator of Cancer Progression and Chemoresistance via Redox?'.,2026-06-07T02:20:35+00:00
31874,toxicity_endpoint,1028,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41743270; Rejected: allele-selective VWF silencing is therapeutic-oligo relevant, but this review passage summarizes prior studies and does not provide a primary administered/measured toxicity endpoint from the article.",2026-06-07T02:20:35+00:00
31875,toxicity_endpoint,1029,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41741661 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31876,toxicity_endpoint,1030,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41725810; Rejected: SAM68 siRNAs are tool knockdowns in HPV-positive cancer cells; reduced cell growth is anticancer/mechanistic efficacy rather than safety.,2026-06-07T02:20:35+00:00
31877,toxicity_endpoint,1031,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41480893; no source passage or abstract wording gives a dependable toxicity call for Sigma-Aldrich.,2026-06-07T02:20:35+00:00
31878,toxicity_endpoint,1032,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41280074 abstract/title reviewed; no clear in-scope general safety/systemic safety/tolerability endpoint is grounded for single.,2026-06-07T02:20:35+00:00
31879,toxicity_endpoint,1033,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40865525; no source passage or abstract wording gives a dependable toxicity call for BIIB078-treated.,2026-06-07T02:20:35+00:00
31880,toxicity_endpoint,1034,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40763041; no source passage or abstract wording gives a dependable toxicity call for PCSK9.,2026-06-07T02:20:35+00:00
31881,toxicity_endpoint,1035,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40501380; Rejected: ASO-Sort1 is therapeutic-oligo relevant, but the loaded passage reports vascular calcification/atherosclerosis efficacy without a safety, toxicity, or tolerability endpoint.",2026-06-07T02:20:35+00:00
31882,toxicity_endpoint,1036,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40339155; available abstract is not enough to curate immunotoxicity/immune activation for significant as a verified toxicity record.,2026-06-07T02:20:35+00:00
31883,toxicity_endpoint,1037,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39955311; significantly remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Antisense oligonucleotide-mediated TRA2β poison exon inclusion induces the expression of a lnc?'.,2026-06-07T02:20:35+00:00
31884,toxicity_endpoint,1038,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39793573; kgHordeolum000001 remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Phase 1/2 trial of brogidirsen: Dual-targeting antisense oligonucleotides for exon 44 skipping?'.,2026-06-07T02:20:35+00:00
31885,toxicity_endpoint,1039,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We also demonstrate enhanced safety in mice, as evidenced by reduced ALT/AST elevation and the absence of histopathological changes.",2026-06-07T02:20:35+00:00
31886,toxicity_endpoint,1040,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41601692 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for single-base.,2026-06-07T02:20:35+00:00
31887,toxicity_endpoint,1041,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41413582; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31888,toxicity_endpoint,1042,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40896584; available abstract is not enough to curate general toxicity/toxicity for Sirius as a verified toxicity record.,2026-06-07T02:20:35+00:00
31889,toxicity_endpoint,1043,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for hematological/thrombocytopenia in similar; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31890,toxicity_endpoint,1044,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39988193; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
31891,toxicity_endpoint,1045,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40977082; Simulations remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Synthesis, Biological Activity, and Molecular Dynamics Simulations of LNA-Charge Neutral Linka?'.",2026-06-07T02:20:35+00:00
31892,toxicity_endpoint,1046,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39829464; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31893,toxicity_endpoint,1047,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41127529; Rejected: inducible ASO targeting Bcl2 is evaluated for tumor-selective gene silencing and cancer cell death; cytotoxicity is intended oncology efficacy, not safety.",2026-06-07T02:20:35+00:00
31894,toxicity_endpoint,1048,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41399806; available abstract is not enough to curate hepatic/hepatotoxicity for size as a verified toxicity record.,2026-06-07T02:20:35+00:00
31895,toxicity_endpoint,1049,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41210516; siRNA-Biopolymer remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'In vivo Therapeutic Inhibition of the Tp53-Induced Glycolysis and Apoptosis Regulator (TIGAR)?'.,2026-06-07T02:20:35+00:00
31896,toxicity_endpoint,1050,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41210170 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31897,toxicity_endpoint,1051,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41155238; Rejected: RNAi in Hevea brasiliensis is agricultural biotechnology for hypoallergenic rubber production, outside therapeutic oligo toxicity scope.",2026-06-07T02:20:35+00:00
31898,toxicity_endpoint,1052,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41070092; Rejected: patisiran/inotersen are therapeutic oligos, but this clinical-trial landscape review provides no primary safety/toxicity result for the reviewed article.",2026-06-07T02:20:35+00:00
31899,toxicity_endpoint,1053,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40708199; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31900,toxicity_endpoint,1054,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40598231; Rejected: lip@si-YTHDF2 is therapeutic-oligo relevant, but the loaded passage only describes safety assay methods and anticancer efficacy, with no primary toxicity result reported.",2026-06-07T02:20:35+00:00
31901,toxicity_endpoint,1055,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40536433; siRNA-Based remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Bioactive siRNA-Based Liposomes Promoted Tendon-Bone Healing in Osteoporotic Mice by Recoverin?'.,2026-06-07T02:20:35+00:00
31902,toxicity_endpoint,1056,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40459540; no source passage or abstract wording gives a dependable toxicity call for signals.,2026-06-07T02:20:35+00:00
31903,toxicity_endpoint,1057,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"produced no overt toxicity, though this study was not designed to detect subtle behavioral changes.",2026-06-07T02:20:35+00:00
31904,toxicity_endpoint,1058,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40289180; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31905,toxicity_endpoint,1059,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40253509; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies.'.,2026-06-07T02:20:35+00:00
31906,toxicity_endpoint,1060,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"These behavioral differences in 1764_S1, but not 112_S1 treated Tg1 mice may indicate adverse effects due to exaggerated pharmacological activity of the siRNA.",2026-06-07T02:20:35+00:00
31907,toxicity_endpoint,1061,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39804640; available abstract is not enough to curate general safety/systemic safety/tolerability for patisiran as a verified toxicity record.,2026-06-07T02:20:35+00:00
31908,toxicity_endpoint,1062,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41510415; 'Inclisiran-Induced Fixed Drug Eruption in a Patient With Refractory Hypercholesterolemia.' does not provide a sufficiently specific administered-oligo toxicity endpoint for inclisiran.,2026-06-07T02:20:35+00:00
31909,toxicity_endpoint,1063,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41477349; Rejected: SMTN siRNA increases DNA damage and chemosensitivity in colorectal cancer cells; this is cancer-cell-killing efficacy, not genotoxicity safety assessment.",2026-06-07T02:20:35+00:00
31910,toxicity_endpoint,1064,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41462626; 'The Regulatory Role of CgALDH6A1 in the Oxidative Stress Response of Crassostrea gigas Under H?' does not provide a sufficiently specific administered-oligo toxicity endpoint for CgALDH6A1.,2026-06-07T02:20:35+00:00
31911,toxicity_endpoint,1065,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41426227 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for unspecified siRNA.,2026-06-07T02:20:35+00:00
31912,toxicity_endpoint,1066,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41394759; significant remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Ribosomal RNA Synthesis is a Lethal Vulnerability During Reductive Stress In C . elegans.'.,2026-06-07T02:20:35+00:00
31913,toxicity_endpoint,1067,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41373402; Rejected: Ptpn22 siRNA lipoplexes are therapeutic-oligo relevant, but the current passage reports in vitro variant knockdown and planned future safety studies, not a primary toxicity endpoint.",2026-06-07T02:20:35+00:00
31914,toxicity_endpoint,1068,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41368817; simplified remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Nucleic acid nanorobot assay for accurate and simplified ASO quantification in mouse plasma.'.,2026-06-07T02:20:35+00:00
31915,toxicity_endpoint,1069,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41360761; significantly remains unsupported for general safety/cell viability/cytotoxicity after abstract-level review of 'LncPEDS1-AS promotes UTUC resistance to lipid peroxidation by regulating PEDS1 expression via?'.,2026-06-07T02:20:35+00:00
31916,toxicity_endpoint,1070,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41295519; Situ remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'In-Situ Self-Assembling Oligomeric Collagen Scaffold Enhances Vaccine Retention and Vaccine-In?'.,2026-06-07T02:20:35+00:00
31917,toxicity_endpoint,1071,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41292795; available abstract is not enough to curate hepatic/hepatotoxicity for following ASO as a verified toxicity record.,2026-06-07T02:20:35+00:00
31918,toxicity_endpoint,1072,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41180755; no source passage or abstract wording gives a dependable toxicity call for olezarsen.,2026-06-07T02:20:35+00:00
31919,toxicity_endpoint,1073,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41166122; 'SLAMF8 expression and prognostic significance in melanoma: A multi-omics and Mendelian randomi?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significance.,2026-06-07T02:20:35+00:00
31920,toxicity_endpoint,1074,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41088451; Rejected: shRNA-recombinant Chlorella is an agricultural/vector-control mosquito biocide, explicitly outside therapeutic oligo scope.",2026-06-07T02:20:35+00:00
31921,toxicity_endpoint,1075,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41069968; the abstained record was checked at abstract level, but general safety/systemic safety/tolerability is still not directly recoverable for inclisiran.",2026-06-07T02:20:35+00:00
31922,toxicity_endpoint,1076,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41050668; Rejected: PTPRG siRNA knockdown reduces multiple myeloma cell viability and increases apoptosis as anticancer functional validation, not safety/toxicity.",2026-06-07T02:20:35+00:00
31923,toxicity_endpoint,1077,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40998932; 'Prognostic signature and tumor microenvironment infiltration based on amino acid metabolism-re?' does not provide a sufficiently specific administered-oligo toxicity endpoint for signature.,2026-06-07T02:20:35+00:00
31924,toxicity_endpoint,1078,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40978076; no source passage or abstract wording gives a dependable toxicity call for signifies.,2026-06-07T02:20:35+00:00
31925,toxicity_endpoint,1079,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40948585; signaling remains unsupported for general safety/cell viability/cytotoxicity after abstract-level review of 'Aminoguanidine-assembled functional DNA tetrahedron alleviates acute lung injury by targeting?'.,2026-06-07T02:20:35+00:00
31926,toxicity_endpoint,1080,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40943068; available abstract is not enough to curate hepatic/hepatotoxicity for Signaling as a verified toxicity record.,2026-06-07T02:20:35+00:00
31927,toxicity_endpoint,1081,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40940654; no source passage or abstract wording gives a dependable toxicity call for inotersen.,2026-06-07T02:20:35+00:00
31928,toxicity_endpoint,1082,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40936676; significant remains unsupported for renal/renal safety after abstract-level review of 'Acute Post-Streptococcal Glomerulonephritis in a 22-Month-Old Toddler: A Rare and Uncustomary?'.,2026-06-07T02:20:35+00:00
31929,toxicity_endpoint,1083,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,This demonstrated that BHF7 does not induce a cytotoxic response either in vitro or ex vivo.,2026-06-07T02:20:35+00:00
31930,toxicity_endpoint,1084,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40896590; 'Targeting a pathogenic cryptic exon that drives HLRCC to induce exon skipping.' does not provide a sufficiently specific administered-oligo toxicity endpoint for silencer.,2026-06-07T02:20:35+00:00
31931,toxicity_endpoint,1085,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40884397; available abstract is not enough to curate hepatic/hepatotoxicity for signs as a verified toxicity record.,2026-06-07T02:20:35+00:00
31932,toxicity_endpoint,1086,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40860346; 'Fracture-Induced Immunological Cascades Trigger Rapid Systemic Bone Loss via Osteocyte-Regulat?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA.,2026-06-07T02:20:35+00:00
31933,toxicity_endpoint,1087,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,with cells dying due to uptake of recNANPs at less than 1%.,2026-06-07T02:20:35+00:00
31934,toxicity_endpoint,1088,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40814374; available abstract is not enough to curate hepatic/hepatotoxicity for significantly as a verified toxicity record.,2026-06-07T02:20:35+00:00
31935,toxicity_endpoint,1089,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40770266; Rejected: siALDH18A1 promotes DNA damage in esophageal cancer cells as a tumor mechanism/target-validation endpoint, not therapeutic oligo genotoxicity safety.",2026-06-07T02:20:35+00:00
31936,toxicity_endpoint,1090,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40699771; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for Cyp2e1.",2026-06-07T02:20:35+00:00
31937,toxicity_endpoint,1091,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40672635; Rejected: SNHG5 siRNA increases apoptosis and reduces OPSCC proliferation/invasion as cancer efficacy/mechanistic validation, not toxicity safety.",2026-06-07T02:20:35+00:00
31938,toxicity_endpoint,1092,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40648843; inclisiran remains unsupported for general safety/systemic safety/tolerability after abstract-level review of 'PCSK9-Targeting Drugs and Gender: Are There Any Differences?'.,2026-06-07T02:20:35+00:00
31939,toxicity_endpoint,1093,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40636269; the abstained record was checked at abstract level, but renal/renal safety is still not directly recoverable for signs.",2026-06-07T02:20:35+00:00
31940,toxicity_endpoint,1094,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40632478 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for lumasiran.,2026-06-07T02:20:35+00:00
31941,toxicity_endpoint,1095,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40597017; Rejected: siRNA/shRNA inhibition of NAT10 or IGF2BP2 suppresses OSCC proliferation/tumorigenicity; this is anticancer efficacy, not safety.",2026-06-07T02:20:35+00:00
31942,toxicity_endpoint,1096,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40586711; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for site.",2026-06-07T02:20:35+00:00
31943,toxicity_endpoint,1097,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40585984; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
31944,toxicity_endpoint,1098,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40574023; 'Optimization of Lipoplexes Functionalized with a Sialic Acid Mimetic (F9-PEG) to Target the C1?' does not provide a sufficiently specific administered-oligo toxicity endpoint for Sialic.,2026-06-07T02:20:35+00:00
31945,toxicity_endpoint,1099,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40572585; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31946,toxicity_endpoint,1100,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40568339; the abstained record was checked at abstract level, but renal/renal safety is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
31947,toxicity_endpoint,1101,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40540492; 'Association of pulmonary artery bifurcation angle shift with contralateral stenosis after post?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significantly.,2026-06-07T02:20:35+00:00
31948,toxicity_endpoint,1102,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40539383; Signaling remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'ASO Therapy Targeting STAU2 to Inhibit Pancreatic Ductal Adenocarcinoma Progression and Metast?'.,2026-06-07T02:20:35+00:00
31949,toxicity_endpoint,1103,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40534660; Rejected: dog JAK1 siRNA is therapeutic-oligo relevant, but the passage reports target silencing/ex vivo delivery efficacy without a measured toxicity endpoint.",2026-06-07T02:20:35+00:00
31950,toxicity_endpoint,1104,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40478750; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
31951,toxicity_endpoint,1105,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40462499 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
31952,toxicity_endpoint,1106,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40365116; available abstract is not enough to curate general safety/cell viability/cytotoxicity for Single-Cell as a verified toxicity record.,2026-06-07T02:20:35+00:00
31953,toxicity_endpoint,1107,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40348775 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for site.,2026-06-07T02:20:35+00:00
31954,toxicity_endpoint,1108,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40309219; Rejected: FXI antisense oligonucleotides are mentioned in a narrative review, but no specific primary ASO safety/toxicity result is reported in the loaded passage.",2026-06-07T02:20:35+00:00
31955,toxicity_endpoint,1109,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40303203 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for lumasiran.,2026-06-07T02:20:35+00:00
31956,toxicity_endpoint,1110,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40270362; Rejected: S-COX11 ASO induces copper-mediated cuproptosis and reduces gastric cancer tumor burden; this is intended cancer-cell-killing efficacy, not safety toxicity.",2026-06-07T02:20:35+00:00
31957,toxicity_endpoint,1111,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40265153; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31958,toxicity_endpoint,1112,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40221835; significantly remains unsupported for general safety/systemic safety/tolerability after abstract-level review of 'Seltoplasmid promotes ulcer healing versus placebo for treating patients with chronic limb-thr?'.,2026-06-07T02:20:35+00:00
31959,toxicity_endpoint,1113,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40169784 abstract/title reviewed; no clear in-scope general toxicity/toxicity endpoint is grounded for tofersen.,2026-06-07T02:20:35+00:00
31960,toxicity_endpoint,1114,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40152945; the abstained record was checked at abstract level, but renal/renal safety is still not directly recoverable for unspecified ASO.",2026-06-07T02:20:35+00:00
31961,toxicity_endpoint,1115,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40064331 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for olezarsen.,2026-06-07T02:20:35+00:00
31962,toxicity_endpoint,1116,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40056974; the abstained record was checked at abstract level, but immunotoxicity/immune activation is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
31963,toxicity_endpoint,1117,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"plasma concentrations of alanine transaminase (ALT) and aspartate aminotransferase (AST), the most widely used clinical biomarkers of MASH, were downregulated in mice dosed with Stk25-targeting ASOs compared with mice in the control groups",2026-06-07T02:20:35+00:00
31964,toxicity_endpoint,1118,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40012043; Rejected: passage describes AEP inhibition/shRNA/siRNA cancer-biology tools and cancer-cell genomic instability or death, not an administered therapeutic oligo safety endpoint.",2026-06-07T02:20:35+00:00
31965,toxicity_endpoint,1119,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40006507; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for size.",2026-06-07T02:20:35+00:00
31966,toxicity_endpoint,1120,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39996142; no source passage or abstract wording gives a dependable toxicity call for inclisiran.,2026-06-07T02:20:35+00:00
31967,toxicity_endpoint,1121,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39991453; 'Pregnancy 3 months after inclisiran injection: a unique case report including newborn baby mon?' does not provide a sufficiently specific administered-oligo toxicity endpoint for inclisiran.,2026-06-07T02:20:35+00:00
31968,toxicity_endpoint,1122,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39962586; Rejected: TUBB2B shRNA knockdown is an anticancer growth and metastasis efficacy experiment, with no therapeutic oligo toxicity or tolerability endpoint.",2026-06-07T02:20:35+00:00
31969,toxicity_endpoint,1123,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39954098; patisiran remains unsupported for general safety/systemic safety/tolerability after abstract-level review of 'Patisiran in ATTRv amyloidosis with polyneuropathy: ""PatisiranItaly"" multicenter observational?'.",2026-06-07T02:20:35+00:00
31970,toxicity_endpoint,1124,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Considerably high cell viabilities after their incubation for 24 h with CSGC and HepG2 cells were obtained (Figure S18,b, Supporting Information), consistent with the low cytotoxicity of the ASO/CDs‐hydrogel composite (Figure S18c, Supporting Information).",2026-06-07T02:20:35+00:00
31971,toxicity_endpoint,1125,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39950613; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for bepirovirsen.",2026-06-07T02:20:35+00:00
31972,toxicity_endpoint,1126,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39938155; significantly remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'MYH knockdown in pancreatic cancer cells creates an exploitable DNA repair vulnerability.'.,2026-06-07T02:20:35+00:00
31973,toxicity_endpoint,1127,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39856697; Rejected: OPN-siRNA is used as a mechanistic tool in LPS/sepsis injury biology and the observed inflammation or mortality is disease-model injury, not oligo toxicity.",2026-06-07T02:20:35+00:00
31974,toxicity_endpoint,1128,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39759873; available abstract is not enough to curate hepatic/hepatotoxicity for single as a verified toxicity record.,2026-06-07T02:20:35+00:00
31975,toxicity_endpoint,1129,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39656824 abstract/title reviewed; no clear in-scope renal/renal safety endpoint is grounded for significantly.,2026-06-07T02:20:35+00:00
31976,toxicity_endpoint,1130,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41392379; Rejected: passage reports computational siRNA design/off-target screening for HPV targets, without administered or measured toxicity/tolerability evidence.",2026-06-07T02:20:35+00:00
31977,toxicity_endpoint,1131,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept C: PubMed abstract gives a weak abstract-level signal for renal/renal safety in siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
31978,toxicity_endpoint,1132,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41340476; Rejected: endothelial MEF2A knockdown uses AAV1-shRNA and mechanistic SIRT1 biology, an explicitly excluded viral shRNA/tool setting without oligo safety evidence.",2026-06-07T02:20:35+00:00
31979,toxicity_endpoint,1133,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41279207; no source passage or abstract wording gives a dependable toxicity call for Tox2.,2026-06-07T02:20:35+00:00
31980,toxicity_endpoint,1134,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41213905; Rejected: MZT2B shRNA/CRISPR effects on NSCLC cell viability and apoptosis are anticancer efficacy readouts, not oligo safety endpoints.",2026-06-07T02:20:35+00:00
31981,toxicity_endpoint,1135,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40143816; 'Gut Microbial Metabolite Imidazole Propionate Impairs Endothelial Cell Function and Promotes t?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA.,2026-06-07T02:20:35+00:00
31982,toxicity_endpoint,1136,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40062663; available abstract is not enough to curate hepatic/hepatotoxicity for signal as a verified toxicity record.,2026-06-07T02:20:35+00:00
31983,toxicity_endpoint,1137,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39989968; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
31984,toxicity_endpoint,1138,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39974881; Single-cell remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Targeting FGFR4 Abrogates HNF1A-driven Metastasis in Pancreatic Ductal Adenocarcinoma.'.,2026-06-07T02:20:35+00:00
31985,toxicity_endpoint,1139,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39958970; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Estrogen and Cyp1b1 Regulate Pparγ in Pulmonary Hypertension Through a Ubiquitin-Dependent Mec?'.,2026-06-07T02:20:35+00:00
31986,toxicity_endpoint,1140,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39949253; no source passage or abstract wording gives a dependable toxicity call for Since.,2026-06-07T02:20:35+00:00
31987,toxicity_endpoint,1141,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To determine whether engineered exosomes have any side effects in vivo, we collected blood samples at the end of the PDX experiment for the detection of ALT, AST, BUN, and CREA. The results showed no significant differences between groups, and there were also no obvious statistical differences in the body weight of mice across the groups (Fig. S7A-D). Major organs from the mice were also collected and subjected to HE staining at the end of the experiment, as shown in Fig.",2026-06-07T02:20:35+00:00
31988,toxicity_endpoint,1142,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39867828 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for significant.,2026-06-07T02:20:35+00:00
31989,toxicity_endpoint,1143,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37980543; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'GalNAc-conjugated siRNA targeting the DNAJB1-PRKACA fusion junction in fibrolamellar hepatocel?'.,2026-06-07T02:20:35+00:00
31990,toxicity_endpoint,1144,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38949758; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for Single-Dose.",2026-06-07T02:20:35+00:00
31991,toxicity_endpoint,1145,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39122967; available abstract is not enough to curate hepatic/hepatotoxicity for The ASO as a verified toxicity record.,2026-06-07T02:20:35+00:00
31992,toxicity_endpoint,1146,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39109217; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31993,toxicity_endpoint,1147,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38654375 abstract/title reviewed; no clear in-scope immunotoxicity/immune activation endpoint is grounded for TREM2.,2026-06-07T02:20:35+00:00
31994,toxicity_endpoint,1148,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38436880; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
31995,toxicity_endpoint,1149,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39525592; no source passage or abstract wording gives a dependable toxicity call for patisiran.,2026-06-07T02:20:35+00:00
31996,toxicity_endpoint,1150,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39327422; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
31997,toxicity_endpoint,1151,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38804718; available abstract is not enough to curate renal/renal safety for silico as a verified toxicity record.,2026-06-07T02:20:35+00:00
31998,toxicity_endpoint,1152,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39303667; 'Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significantly.,2026-06-07T02:20:35+00:00
31999,toxicity_endpoint,1153,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38511173; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for Similarly.",2026-06-07T02:20:35+00:00
32000,toxicity_endpoint,1154,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39373509; pTrc99a remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Pathological R-loops in bacteria from engineered expression of endogenous antisense RNAs whose?'.,2026-06-07T02:20:35+00:00
32001,toxicity_endpoint,1155,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39339854 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
32002,toxicity_endpoint,1156,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To evaluate safety, we performed electroretinogram (ERG) recordings under scotopic (rod PR cell response) and photopic (cone PR cell response) conditions, which revealed no significant differences among the different dose groups (Figures 3C and S2). Similarly, immunohistochemical analyses of retinal cross-sections detected no migration of microglia marked by ionized calcium binding adaptor molecule 1 (Iba1) into the ONL and/or inner outer segment region, except for occasional cells at the highest dose (60 μg; arrowheads, Figure 3D). Consistent with this, there was no reactive gliosis in the retina as assessed by the normal expression of glial fibrillary acidic protein (GFAP) (Figure 3E).",2026-06-07T02:20:35+00:00
32003,toxicity_endpoint,1157,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39795992; no source passage or abstract wording gives a dependable toxicity call for unspecified ASO.,2026-06-07T02:20:35+00:00
32004,toxicity_endpoint,1158,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39749345; Rejected: passage concerns a prognostic ROS signature and AKR1B1 validation in bladder cancer, with no therapeutic oligo administered or safety endpoint.",2026-06-07T02:20:35+00:00
32005,toxicity_endpoint,1159,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39622652; Rejected: Acanthamoeba siRNAs are functional knockdown tools for excystation biology, not therapeutic oligo toxicity or tolerability evidence.",2026-06-07T02:20:35+00:00
32006,toxicity_endpoint,1160,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39598377; Rejected: siRNAs are used in an RNAi screen to sensitize cancer cells to cannabinoid treatment; cell viability is anticancer efficacy, not safety toxicity.",2026-06-07T02:20:35+00:00
32007,toxicity_endpoint,1161,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Renal AEs included an early but transient moderate increase in serum creatinine (30.7%) or a reduction in the eGFR (11.5%, Table 2). In total, 15.4% of patients experienced a mild elevation of liver enzyme activities (<1.5 UNL, [AST/ALT]), with a further 7.7% of patients’ liver enzyme activities elevated further (>1.5ULN, [AST/ALT]). There were no episodes of pancreatitis.",2026-06-07T02:20:35+00:00
32008,toxicity_endpoint,1162,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39574583; significant remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced f?'.,2026-06-07T02:20:35+00:00
32009,toxicity_endpoint,1163,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39534236; significantly remains unsupported for general safety/systemic safety/tolerability after abstract-level review of 'Using the Failure Mode and Effect Analysis Tool to Improve the Automatic Stop Order Process.'.,2026-06-07T02:20:35+00:00
32010,toxicity_endpoint,1164,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39479289; inclisiran remains unsupported for general safety/systemic safety/tolerability after abstract-level review of 'PCSK9 Inhibitors: The Evolving Future.'.,2026-06-07T02:20:35+00:00
32011,toxicity_endpoint,1165,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 39475170; the abstained record was checked at abstract level, but renal/renal safety is still not directly recoverable for Single.",2026-06-07T02:20:35+00:00
32012,toxicity_endpoint,1166,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39418102; 'Knockdown of ketohexokinase versus inhibition of its kinase activity exert divergent effects o?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA.,2026-06-07T02:20:35+00:00
32013,toxicity_endpoint,1167,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39261477; 'Association of ADAM family members with proliferation signaling and disease progression in mul?' does not provide a sufficiently specific administered-oligo toxicity endpoint for signaling.,2026-06-07T02:20:35+00:00
32014,toxicity_endpoint,1168,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39258007; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Gene editing of angiotensin for blood pressure management.'.,2026-06-07T02:20:35+00:00
32015,toxicity_endpoint,1169,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39238094; 'Suppressing upregulation of fibrinogen after polytrauma mitigates thrombosis in mice.' does not provide a sufficiently specific administered-oligo toxicity endpoint for siFibrinogen.,2026-06-07T02:20:35+00:00
32016,toxicity_endpoint,1170,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39131369; no source passage or abstract wording gives a dependable toxicity call for signaling.,2026-06-07T02:20:35+00:00
32017,toxicity_endpoint,1171,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39027255; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'LncRNA ZFPM2-AS1 promotes phyllodes tumor progression by binding to CDC42 and inhibiting STAT1?'.,2026-06-07T02:20:35+00:00
32018,toxicity_endpoint,1172,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To determine if SOD1 reduction by di-siRNASOD1_123 exNA in G93A mice impacted neurogliosis, we evaluated astrocyte and microglial morphology in the cortex and spinal cord. In the cortex, there was no evidence of either astrogliosis (Figure S3A,C) or microgliosis (Figure S4A,C) between wild-type, transgenic non-mutant or transgenic mutant untreated mice, while both phenomena were enhanced in di-siRNASOD1_123 exNA treated G93A mice. By contrast, in the lumbar spinal cord, untreated G93A mice exhibit both astrogliosis (Figure S3B,D) and microgliosis (Figure S4B,D) compared to wild-type or non-mutant transgenic mice that was unaffected by the di-siRNASOD1_123 exNA treatment. Taken together, these immunohistochemistry findings suggest that di-siRNASOD1_123 exNA treatment maintains synapse structure and protects against the synapse loss observed in untreated ALS mice.",2026-06-07T02:20:35+00:00
32019,toxicity_endpoint,1173,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38968577; 'LncRNA DANCR promotes macrophage lipid accumulation through modulation of membrane cholesterol?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significantly.,2026-06-07T02:20:35+00:00
32020,toxicity_endpoint,1174,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38910594; no source passage or abstract wording gives a dependable toxicity call for unspecified ASO.,2026-06-07T02:20:35+00:00
32021,toxicity_endpoint,1175,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38864216; Rejected: lincRNA-p21 ASO attenuates cardiac hypertrophy and adverse remodeling as a disease-efficacy endpoint; the passage does not measure ASO toxicity or tolerability.,2026-06-07T02:20:35+00:00
32022,toxicity_endpoint,1176,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38811958; Rejected: PXN-AS1/miR-635/GS signaling work concerns CML imatinib-resistance biology and knockdown efficacy, not a therapeutic oligo safety endpoint.",2026-06-07T02:20:35+00:00
32023,toxicity_endpoint,1177,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38807667; Rejected: PLK1 siRNA/inhibitor assays measure cholangiocarcinoma antiproliferative apoptosis and DNA damage efficacy, an excluded cancer-cell-killing endpoint.",2026-06-07T02:20:35+00:00
32024,toxicity_endpoint,1178,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38742209; lumasiran remains unsupported for renal/renal safety after abstract-level review of 'Lumasiran treatment in pediatric patients with PH1: real-world data within a compassionate use?'.,2026-06-07T02:20:35+00:00
32025,toxicity_endpoint,1179,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Meanwhile, body weight of the mice did not have significant changes, and no adverse effects were noticeably observed during and after the treatments (Fig.",2026-06-07T02:20:35+00:00
32026,toxicity_endpoint,1180,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for general safety/systemic safety/tolerability in nusinersen; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
32027,toxicity_endpoint,1181,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38706897; Rejected: PubMed abstract describes PSAT1/PI3K/AKT colorectal-cancer signaling with no therapeutic oligo product or toxicity measurement.,2026-06-07T02:20:35+00:00
32028,toxicity_endpoint,1182,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38622453; no source passage or abstract wording gives a dependable toxicity call for patisiran.,2026-06-07T02:20:35+00:00
32029,toxicity_endpoint,1183,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38473072; Rejected: ASO here denotes andiroba seed oil rather than an oligonucleotide; cell viability effects of the oil are outside oligo scope.,2026-06-07T02:20:35+00:00
32030,toxicity_endpoint,1184,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38464227; no source passage or abstract wording gives a dependable toxicity call for SIRT2.,2026-06-07T02:20:35+00:00
32031,toxicity_endpoint,1185,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38464017; available abstract is not enough to curate hepatic/hepatotoxicity for significantly as a verified toxicity record.,2026-06-07T02:20:35+00:00
32032,toxicity_endpoint,1186,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38429929; Rejected: anti-ATXN3 ASO rescues disease-associated oligodendrocyte signatures, but the loaded passage does not provide a safety/toxicity/tolerability endpoint.",2026-06-07T02:20:35+00:00
32033,toxicity_endpoint,1187,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38406263; 'SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diff?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA-mediated.,2026-06-07T02:20:35+00:00
32034,toxicity_endpoint,1188,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38390737 abstract/title reviewed; no clear in-scope general toxicity/toxicity endpoint is grounded for NPM1.,2026-06-07T02:20:35+00:00
32035,toxicity_endpoint,1189,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38384337; no source passage or abstract wording gives a dependable toxicity call for tofersen.,2026-06-07T02:20:35+00:00
32036,toxicity_endpoint,1190,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 38360682; Rejected: circPDHK1 experiments use siRNAs/plasmids/lentivirus to study renal-cancer tumorigenesis and metastasis, not oligo safety.",2026-06-07T02:20:35+00:00
32037,toxicity_endpoint,1191,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38331987; 'Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma.' does not provide a sufficiently specific administered-oligo toxicity endpoint for significant.,2026-06-07T02:20:35+00:00
32038,toxicity_endpoint,1192,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38287401; 'Correlations between genetically predicted lipid-lowering drug targets and inflammatory bowel?' does not provide a sufficiently specific administered-oligo toxicity endpoint for volanesorsen.,2026-06-07T02:20:35+00:00
32039,toxicity_endpoint,1193,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38183981; available abstract is not enough to curate hepatic/hepatotoxicity for silencing as a verified toxicity record.,2026-06-07T02:20:35+00:00
32040,toxicity_endpoint,1194,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38182646; 'QR-1011 restores defective ABCA4 splicing caused by multiple severe ABCA4 variants underlying?' does not provide a sufficiently specific administered-oligo toxicity endpoint for site.,2026-06-07T02:20:35+00:00
32041,toxicity_endpoint,1195,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39375761 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
32042,toxicity_endpoint,1196,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39684389; Rejected: dsRNA silencing in the invasive weed Mikania micrantha is agricultural/plant RNAi and explicitly outside the therapeutic oligo toxicity scope.,2026-06-07T02:20:35+00:00
32043,toxicity_endpoint,1197,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39258005; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'TME-Responsive Nanoplatform with Glutathione Depletion for Enhanced Tumor-Specific Mild Photot?'.,2026-06-07T02:20:35+00:00
32044,toxicity_endpoint,1198,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"To further evaluate the in vivo toxicity of siPDL1‐CaP@PD1‐NVs, the serum and major organs (heart, liver, spleen, lung, kidney) were collected from the mice in different groups. H&E staining of important organs showed no obvious tissue morphological changes and intact cell morphology with distinct nucleus and cytoplasm (Figure S20, Supporting Information). Additionally, the serum biochemical markers also showed no significant change in any groups (Figure S21, Supporting Information). The results indicated that siPDL1‐CaP@PD1‐NVs possessed excellent in vivo safety with negligible side effects.",2026-06-07T02:20:35+00:00
32045,toxicity_endpoint,1199,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38255113; available abstract is not enough to curate general safety/systemic safety/tolerability for and ASO as a verified toxicity record.,2026-06-07T02:20:35+00:00
32046,toxicity_endpoint,1200,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36454263 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for signals.,2026-06-07T02:20:35+00:00
32047,toxicity_endpoint,1201,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37824025; 'Plasma Pharmacokinetics of N-Acetylgalactosamine-Conjugated Small-Interfering Ribonucleic Acid?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNAs.,2026-06-07T02:20:35+00:00
32048,toxicity_endpoint,1202,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37036788; available abstract is not enough to curate general toxicity/toxicity for hDMDdel52 as a verified toxicity record.,2026-06-07T02:20:35+00:00
32049,toxicity_endpoint,1203,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Overall, interferon signaling appeared to be similarly induced by all ASOs, while interleukin signaling was more prominent for the repeat gapmer and control gapmer (Figure 3A).",2026-06-07T02:20:35+00:00
32050,toxicity_endpoint,1204,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36910710; no source passage or abstract wording gives a dependable toxicity call for ABCA4.,2026-06-07T02:20:35+00:00
32051,toxicity_endpoint,1205,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37788110 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for similarity.,2026-06-07T02:20:35+00:00
32052,toxicity_endpoint,1206,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36893269; the abstained record was checked at abstract level, but general toxicity/toxicity is still not directly recoverable for siRNAs.",2026-06-07T02:20:35+00:00
32053,toxicity_endpoint,1207,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36669889; no source passage or abstract wording gives a dependable toxicity call for nusinersen.,2026-06-07T02:20:35+00:00
32054,toxicity_endpoint,1208,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36576986; Reject: KCNH2 siRNA is explicitly used as a positive-control/tool siRNA for hERG assay development; the viability measurement is not a therapeutic oligo safety endpoint.,2026-06-07T02:20:35+00:00
32055,toxicity_endpoint,1209,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37893074; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for AD3-CL1.",2026-06-07T02:20:35+00:00
32056,toxicity_endpoint,1210,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37853497; available abstract is not enough to curate hepatic/hepatotoxicity for similarity as a verified toxicity record.,2026-06-07T02:20:35+00:00
32057,toxicity_endpoint,1211,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37460153; Reject: bepirovirsen is in scope, but the passage reports liver/kidney localization and tissue distribution, not hepatic toxicity or another safety endpoint.",2026-06-07T02:20:35+00:00
32058,toxicity_endpoint,1212,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37095250; no source passage or abstract wording gives a dependable toxicity call for similar.,2026-06-07T02:20:35+00:00
32059,toxicity_endpoint,1213,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37554515; Reject: RNAi/shRNA sequences are used for prostate cancer cell killing efficacy and screening; this is excluded cancer-cell-killing cytotoxicity efficacy, not oligo toxicity.",2026-06-07T02:20:35+00:00
32060,toxicity_endpoint,1214,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Blood chemistry and CBC profiles were similar between si3033 and PBS-injected mice except there was a transient decrease of platelet counts in the siRNA-treated mice (Fig. 3c).,2026-06-07T02:20:35+00:00
32061,toxicity_endpoint,1215,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38069409; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
32062,toxicity_endpoint,1216,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 38028198; significant remains unsupported for immunotoxicity/immune activation after abstract-level review of 'ASO-mediated knockdown or kinase inhibition of G2019S-Lrrk2 modulates lysosomal tubule-associa?'.,2026-06-07T02:20:35+00:00
32063,toxicity_endpoint,1217,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37965143; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for single.",2026-06-07T02:20:35+00:00
32064,toxicity_endpoint,1218,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37901602; Reject: RNAi is used as a Drosophila genetic screen to identify transcriptional regulators of photoreceptor survival; degeneration/cell death is target biology, not administered therapeutic oligo toxicity.",2026-06-07T02:20:35+00:00
32065,toxicity_endpoint,1219,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37803087 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for similar.,2026-06-07T02:20:35+00:00
32066,toxicity_endpoint,1220,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Adverse events by week 66 that led to study drug discontinuation occurred in 6 patients (4%) in the eplontersen group vs 2 (3%) in the placebo group.,2026-06-07T02:20:35+00:00
32067,toxicity_endpoint,1221,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37745122; available abstract is not enough to curate general toxicity/toxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
32068,toxicity_endpoint,1222,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37707791; available abstract is not enough to curate hepatic/hepatotoxicity for similar as a verified toxicity record.,2026-06-07T02:20:35+00:00
32069,toxicity_endpoint,1223,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37675986; the abstained record was checked at abstract level, but general toxicity/toxicity is still not directly recoverable for HEK293.",2026-06-07T02:20:35+00:00
32070,toxicity_endpoint,1224,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37523143; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for patisiran.",2026-06-07T02:20:35+00:00
32071,toxicity_endpoint,1225,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37507701; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
32072,toxicity_endpoint,1226,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37503274; available abstract is not enough to curate hepatic/hepatotoxicity for Both ASO as a verified toxicity record.,2026-06-07T02:20:35+00:00
32073,toxicity_endpoint,1227,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37435531; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for Simple.",2026-06-07T02:20:35+00:00
32074,toxicity_endpoint,1228,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37235843 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for signaling.,2026-06-07T02:20:35+00:00
32075,toxicity_endpoint,1229,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35965411; available abstract is not enough to curate hepatic/hepatotoxicity for silencing as a verified toxicity record.,2026-06-07T02:20:35+00:00
32076,toxicity_endpoint,1230,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37038354; Reject: the ERBB2 aptamer passage reports PET tissue pharmacokinetics, biodistribution, and excretion routes, not observed toxicity or tolerability.",2026-06-07T02:20:35+00:00
32077,toxicity_endpoint,1231,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 37847372; Reject: this is a roadmap/review discussion of C9ORF72 disease mechanisms and therapeutic strategies; RNA toxicity refers to endogenous disease biology, not primary administered oligo safety.",2026-06-07T02:20:35+00:00
32078,toxicity_endpoint,1232,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37660254; available abstract is not enough to curate hepatic/hepatotoxicity for significant as a verified toxicity record.,2026-06-07T02:20:35+00:00
32079,toxicity_endpoint,1233,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 37122688; siRNA-mediated remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Hepatocyte mARC1 promotes fatty liver disease.'.,2026-06-07T02:20:35+00:00
32080,toxicity_endpoint,1234,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36993169; 'Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo.' does not provide a sufficiently specific administered-oligo toxicity endpoint for single.,2026-06-07T02:20:35+00:00
32081,toxicity_endpoint,1235,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36788535; no source passage or abstract wording gives a dependable toxicity call for some ASO.,2026-06-07T02:20:35+00:00
32082,toxicity_endpoint,1236,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36692196; single-center remains unsupported for renal/renal safety after abstract-level review of 'Acute kidney injury after arterial switch operation: incidence, risk factors, clinical impact?'.",2026-06-07T02:20:35+00:00
32083,toxicity_endpoint,1237,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36583853 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
32084,toxicity_endpoint,1238,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35921401; Reject: the passage mainly reports siRNA chemistry, potency, off-target mitigation, and a biochemical mitochondrial polymerase substrate assay used to infer safety; no direct administered/measured toxicity endpoint is reported.",2026-06-07T02:20:35+00:00
32085,toxicity_endpoint,1239,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36195542; 'Volanesorsen, an antisense oligonucleotide to apolipoprotein C-III, increases lipoprotein lipa?' does not provide a sufficiently specific administered-oligo toxicity endpoint for volanesorsen.",2026-06-07T02:20:35+00:00
32086,toxicity_endpoint,1240,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In separate experiments, injection of two different doses of ANGPTL4 ASO over 20 weeks of high-fat feeding reduced hepatic and adipose ANGPTL4 levels but did not trigger mesenteric lymphadenopathy, an acute phase response, chylous ascites, or any other pathological phenotypes.",2026-06-07T02:20:35+00:00
32087,toxicity_endpoint,1241,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35208958; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
32088,toxicity_endpoint,1242,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36126230 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for simulations.,2026-06-07T02:20:35+00:00
32089,toxicity_endpoint,1243,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35671982; available abstract is not enough to curate hepatic/hepatotoxicity for significantly as a verified toxicity record.,2026-06-07T02:20:35+00:00
32090,toxicity_endpoint,1244,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Gapmer mixed-modified and DNA oligonucleotides on a phosphorothioate backbone can bind non-specifically to intracellular proteins to form a variety of toxic inclusions, driven by the phosphorothioate linkages, but also influenced by the oligonucleotide sequence.",2026-06-07T02:20:35+00:00
32091,toxicity_endpoint,1245,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35720575; Reject: Physaria fendleri SDP1 RNAi is an agricultural/plant oil-biosynthesis study, explicitly out of therapeutic oligo toxicity scope.",2026-06-07T02:20:35+00:00
32092,toxicity_endpoint,1246,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35109796; Reject: siRBM3 is an in vitro knockdown tool in bladder cancer chemosensitivity experiments; cytotoxicity refers to cisplatin/gemcitabine efficacy, not oligo safety.",2026-06-07T02:20:35+00:00
32093,toxicity_endpoint,1247,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The advanced siRNA did not stimulate IL-6 levels but caused a non-significant increase in IL-12 levels (IL-6: 0.8, IL-12: 1.7) (Figure 8B).",2026-06-07T02:20:35+00:00
32094,toxicity_endpoint,1248,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 35795486; Reject: PK-modifying anchor data concern siRNA clearance, biodistribution, tissue exposure, and silencing efficacy, not toxicity or tolerability endpoints.",2026-06-07T02:20:35+00:00
32095,toxicity_endpoint,1249,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35364120; available abstract is not enough to curate general safety/cell viability/cytotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
32096,toxicity_endpoint,1250,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35251767; Reject: guide-strand bulge experiments measure siRNA repression/activity in hepatocytes and mice; no immune activation or other toxicity endpoint is reported in the passage.,2026-06-07T02:20:35+00:00
32097,toxicity_endpoint,1251,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34893881; available abstract is not enough to curate hepatic/hepatotoxicity for significantly as a verified toxicity record.,2026-06-07T02:20:35+00:00
32098,toxicity_endpoint,1252,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 36575422; Reject: siRNA-CXCR1 is a validation/knockdown tool in an asthma-COVID cell model; reduced cell viability is target biology/model validation, not oligo product toxicity.",2026-06-07T02:20:35+00:00
32099,toxicity_endpoint,1253,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36333801; Reject: menin/DOT1L siRNA experiments are cancer-cell proliferation/viability efficacy assays and not therapeutic oligo safety or toxicity endpoints.,2026-06-07T02:20:35+00:00
32100,toxicity_endpoint,1254,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36257830; Reject: AKT-shRNA is delivered by AAV as a genetic manipulation tool in a ketamine/lithium behavior study; AAV/shRNA tools are excluded and body weight is not oligo toxicity here.,2026-06-07T02:20:35+00:00
32101,toxicity_endpoint,1255,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35393769; 'Cardio-respiratory and phenotypic rescue of dystrophin/utrophin-deficient mice by combination?' does not provide a sufficiently specific administered-oligo toxicity endpoint for unspecified PMO.,2026-06-07T02:20:35+00:00
32102,toxicity_endpoint,1256,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35369705; significant remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Effect of Vupanorsen on Non-High-Density Lipoprotein Cholesterol Levels in Statin-Treated Pati?'.,2026-06-07T02:20:35+00:00
32103,toxicity_endpoint,1257,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"A significant decrease in platelet count (p = 0.001, Friedman test) was observed from baseline to month 6 (M6), but no patient permanently discontinued the treatment because of this reason and no severe thrombocytopenia (<50.000 per cubic millimeter) occurred.",2026-06-07T02:20:35+00:00
32104,toxicity_endpoint,1258,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35207255; volanesorsen remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Volanesorsen: A New Era in the Treatment of Severe Hypertriglyceridemia.'.,2026-06-07T02:20:35+00:00
32105,toxicity_endpoint,1259,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35102341; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
32106,toxicity_endpoint,1260,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35025993 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for olezarsen.,2026-06-07T02:20:35+00:00
32107,toxicity_endpoint,1261,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 34853819; no source passage or abstract wording gives a dependable toxicity call for siPLK1.,2026-06-07T02:20:35+00:00
32108,toxicity_endpoint,1262,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 35423918; 'Evaluation of DNA segments in 2'-modified RNA sequences in designing efficient splice switchin?' does not provide a sufficiently specific administered-oligo toxicity endpoint for sites.,2026-06-07T02:20:35+00:00
32109,toxicity_endpoint,1263,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in Single-Stranded; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
32110,toxicity_endpoint,1264,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33850637; Reject: shRNAs/siRNAs are used to induce prostate cancer cell death and validate androgen-signaling survival networks; this is excluded cancer-cell-killing efficacy/tool RNAi, not oligo toxicity.",2026-06-07T02:20:35+00:00
32111,toxicity_endpoint,1265,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33577678 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for PS-cEt ASO.,2026-06-07T02:20:35+00:00
32112,toxicity_endpoint,1266,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 34918046; Reject: the self-assembled mHTT siRNA passage reports delivery and Huntington disease efficacy; toxicity language concerns disease aggregates or general risks, with no primary safety endpoint for the administered product.",2026-06-07T02:20:35+00:00
32113,toxicity_endpoint,1267,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33707773 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for pathology19.,2026-06-07T02:20:35+00:00
32114,toxicity_endpoint,1268,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33577685; Reject: 2-F-NMC siRNA work reports activity and mitochondrial polymerase substrate testing to predict metabolite safety, but no direct toxicity/tolerability endpoint for an administered oligo product.",2026-06-07T02:20:35+00:00
32115,toxicity_endpoint,1269,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32311310; Reject: full-phosphorothioate siRNA passage reports stability, biodistribution, and antitumor efficacy; toxicity statements are background/literature rather than primary safety endpoints.",2026-06-07T02:20:35+00:00
32116,toxicity_endpoint,1270,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,Grade adjusted B->A: PMID 34172725; full-text grounding and high confidence outweighed the conservative v2 grade for hepatic/hepatotoxicity.,2026-06-07T02:20:35+00:00
32117,toxicity_endpoint,1271,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33883545; Rejected: AAV2/9 shRNA gene-therapy product is explicitly out of scope under the toxicity v2 exclusions for AAV/shRNA, despite immune/off-target statements.",2026-06-07T02:20:35+00:00
32118,toxicity_endpoint,1272,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33651408; available abstract is not enough to curate hepatic/hepatotoxicity for situ as a verified toxicity record.,2026-06-07T02:20:35+00:00
32119,toxicity_endpoint,1273,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33164048; TCID50 remains unsupported for general safety/cell viability/cytotoxicity after abstract-level review of 'Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers.'.,2026-06-07T02:20:35+00:00
32120,toxicity_endpoint,1274,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32269522 abstract/title reviewed; no clear in-scope general toxicity/toxicity endpoint is grounded for antimiR132.,2026-06-07T02:20:35+00:00
32121,toxicity_endpoint,1275,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32146420; 'Dose-Finding Study and Pharmacokinetics Profile of the Novel 13-Mer Antisense miR-221 Inhibito?' does not provide a sufficiently specific administered-oligo toxicity endpoint for unspecified ASO.,2026-06-07T02:20:35+00:00
32122,toxicity_endpoint,1276,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 32670352; Rejected: passage concerns Artemisia essential oil toxicity and agricultural pest transcriptomics, not an administered therapeutic oligonucleotide safety endpoint.",2026-06-07T02:20:35+00:00
32123,toxicity_endpoint,1277,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32307524; Rejected: ALS/SCA2 transcriptomics passage does not provide an administered therapeutic oligonucleotide toxicity or tolerability endpoint.,2026-06-07T02:20:35+00:00
32124,toxicity_endpoint,1278,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32860031 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for site.,2026-06-07T02:20:35+00:00
32125,toxicity_endpoint,1279,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32529301; Simultaneous remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Simultaneous analysis of multiple oligonucleotides by temperature-responsive chromatography us?'.,2026-06-07T02:20:35+00:00
32126,toxicity_endpoint,1280,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 36968157; significantly remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Gene modification strategies using AO-mediated exon skipping and CRISPR/Cas9 as potential ther?'.,2026-06-07T02:20:35+00:00
32127,toxicity_endpoint,1281,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 33426226; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for CD8.",2026-06-07T02:20:35+00:00
32128,toxicity_endpoint,1282,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 33024974; no source passage or abstract wording gives a dependable toxicity call for unspecified PMO.,2026-06-07T02:20:35+00:00
32129,toxicity_endpoint,1283,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 32982982; 'Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Ent?' does not provide a sufficiently specific administered-oligo toxicity endpoint for Side.,2026-06-07T02:20:35+00:00
32130,toxicity_endpoint,1284,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31873216; no source passage or abstract wording gives a dependable toxicity call for components1.,2026-06-07T02:20:35+00:00
32131,toxicity_endpoint,1285,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31322739; available abstract is not enough to curate hepatic/hepatotoxicity for patisiran as a verified toxicity record.,2026-06-07T02:20:35+00:00
32132,toxicity_endpoint,1286,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 30570431; no source passage or abstract wording gives a dependable toxicity call for single.,2026-06-07T02:20:35+00:00
32133,toxicity_endpoint,1287,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31632266; no source passage or abstract wording gives a dependable toxicity call for of ASO.,2026-06-07T02:20:35+00:00
32134,toxicity_endpoint,1288,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30772256; Rejected: Pnpla3 ASO liver/ALT findings are NASH efficacy or disease-biomarker outcomes; the only clear safety-style sentence is for a scrambled control ASO, not the therapeutic Pnpla3 ASO endpoint.",2026-06-07T02:20:35+00:00
32135,toxicity_endpoint,1289,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Furthermore, mild histological changes observed in liver or kidney 2 weeks after Pip6a-PMO injections were mostly reversed 6 months later (Supplemental Table 5), supporting transient and reversible side effects of Pip6a-PMO treatment.",2026-06-07T02:20:35+00:00
32136,toxicity_endpoint,1290,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31097994 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for Simplifying.,2026-06-07T02:20:35+00:00
32137,toxicity_endpoint,1291,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 31070517; available abstract is not enough to curate hepatic/hepatotoxicity for single-dose as a verified toxicity record.,2026-06-07T02:20:35+00:00
32138,toxicity_endpoint,1292,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"The frozen RGD-PEG-ECO/siβ3 nanoparticle formulation exhibits excellent biocompatibility, with no adverse effects on hemocompatibility and minimal immunogenicity.",2026-06-07T02:20:35+00:00
32139,toxicity_endpoint,1293,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"We did not observe any variability in biomarkers of kidney toxicity, including blood urea nitrogen and creatinine levels (Supplementary Figure S5).",2026-06-07T02:20:35+00:00
32140,toxicity_endpoint,1294,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 30467420; 'TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to the potent inh?' does not provide a sufficiently specific administered-oligo toxicity endpoint for TLR9.",2026-06-07T02:20:35+00:00
32141,toxicity_endpoint,1295,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 30020852 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for significant.,2026-06-07T02:20:35+00:00
32142,toxicity_endpoint,1296,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29806836; available abstract is not enough to curate hepatic/hepatotoxicity for nusinersen as a verified toxicity record.,2026-06-07T02:20:35+00:00
32143,toxicity_endpoint,1297,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"In a single dose setting of 900 μg per eye, QR-110 was well tolerated for up to 28 days, and no adverse findings related to QR-110 were observed (Figure S4).",2026-06-07T02:20:35+00:00
32144,toxicity_endpoint,1298,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29972757; inotersen remains unsupported for hematological/thrombocytopenia after abstract-level review of 'Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis.'.,2026-06-07T02:20:35+00:00
32145,toxicity_endpoint,1299,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 29316633; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
32146,toxicity_endpoint,1300,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 29246294; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for sites.",2026-06-07T02:20:35+00:00
32147,toxicity_endpoint,1301,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 29246296; 'Antisense Oligonucleotides Targeting Y-Box Binding Protein-1 Inhibit Tumor Angiogenesis by Dow?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significant.,2026-06-07T02:20:35+00:00
32148,toxicity_endpoint,1302,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 27285612; no source passage or abstract wording gives a dependable toxicity call for significant.,2026-06-07T02:20:35+00:00
32149,toxicity_endpoint,1303,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 26573217; unspecified siRNA remains unsupported for general safety/systemic safety/tolerability after abstract-level review of 'Longitudinal effect of eteplirsen versus historical control on ambulation in Duchenne muscular?'.,2026-06-07T02:20:35+00:00
32150,toxicity_endpoint,1304,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 26623937; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significant.",2026-06-07T02:20:35+00:00
32151,toxicity_endpoint,1305,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 25915865; Rejected: toxicity testing is for an LNA/2OMe FISH diagnostic probe/tool oligonucleotide, not a therapeutic oligo product.",2026-06-07T02:20:35+00:00
32152,toxicity_endpoint,1306,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Importantly, histology suggested no toxicity caused by the treatments in any of the tissues evaluated; this corresponded to a stable body weight growth of the treated animals (Supplementary Figure S13).",2026-06-07T02:20:35+00:00
32153,toxicity_endpoint,1307,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 23344236; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for similar.",2026-06-07T02:20:35+00:00
32154,toxicity_endpoint,1308,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 22108858; no source passage or abstract wording gives a dependable toxicity call for PCSK9.,2026-06-07T02:20:35+00:00
32155,toxicity_endpoint,1309,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 23344237; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
32156,toxicity_endpoint,1310,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 20924365; no source passage or abstract wording gives a dependable toxicity call for signal.,2026-06-07T02:20:35+00:00
32157,toxicity_endpoint,1311,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42018666; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for single.",2026-06-07T02:20:35+00:00
32158,toxicity_endpoint,1312,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41663223 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for silica-based.,2026-06-07T02:20:35+00:00
32159,toxicity_endpoint,1313,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42173448; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Biomimetic lipid nanoparticles for macrophage reprogramming in cancer immunotherapy.'.,2026-06-07T02:20:35+00:00
32160,toxicity_endpoint,1314,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41949512; single remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Efficacy of Tonlamarsen in Patients With Uncontrolled Hypertension: The KARDINAL Phase 2 Rando?'.,2026-06-07T02:20:35+00:00
32161,toxicity_endpoint,1315,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41832731; Rejected: review abstract discusses siRNA design resources and future safety modeling needs, not a primary administered/measured toxicity endpoint.",2026-06-07T02:20:35+00:00
32162,toxicity_endpoint,1316,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41707138; available abstract is not enough to curate hepatic/hepatotoxicity for single as a verified toxicity record.,2026-06-07T02:20:35+00:00
32163,toxicity_endpoint,1317,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"After three rounds of screening-evaluating gene silencing efficiency (in vitro and in vivo), LNP physicochemical properties and biosafety─we identify a lead candidate formulation (Formulation 1) that achieves 85% MUC5AC silencing efficiency in vivo, outperforming the integrin αvβ6 ligand-modified siRNA (69%), and demonstrates notably improved biosafety when compared to SM102 LNPs and MC3 LNPs.",2026-06-07T02:20:35+00:00
32164,toxicity_endpoint,1318,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41528981; 'A Phase II Trial of an Extended-Release siRNA Implant Targeting KRASG12D/V in Locally Advanced?' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA.,2026-06-07T02:20:35+00:00
32165,toxicity_endpoint,1319,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41213485; available abstract is not enough to curate renal/renal safety for similar as a verified toxicity record.,2026-06-07T02:20:35+00:00
32166,toxicity_endpoint,1320,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41849580 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for sites.,2026-06-07T02:20:35+00:00
32167,toxicity_endpoint,1321,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41265187; siRNA-mediated remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Novel nanoparticle-combined therapy through EGFR and PD-L1 blockade: PFPR-siRNA-mediated suppr?'.,2026-06-07T02:20:35+00:00
32168,toxicity_endpoint,1322,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40999856; Rejected: agricultural/storage-pest RNAi mortality study is excluded and not a therapeutic oligonucleotide safety endpoint.,2026-06-07T02:20:35+00:00
32169,toxicity_endpoint,1323,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40769373 abstract/title reviewed; no clear in-scope general safety/systemic safety/tolerability endpoint is grounded for inclisiran.,2026-06-07T02:20:35+00:00
32170,toxicity_endpoint,1324,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42208637; available abstract is not enough to curate hepatic/hepatotoxicity for single as a verified toxicity record.,2026-06-07T02:20:35+00:00
32171,toxicity_endpoint,1325,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42206582; 'Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection.' does not provide a sufficiently specific administered-oligo toxicity endpoint for bepirovirsen.,2026-06-07T02:20:35+00:00
32172,toxicity_endpoint,1326,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42203013; significantly remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'R-loop-associated regulator VDAC1 drives malignant phenotypes in uveal melanoma.'.,2026-06-07T02:20:35+00:00
32173,toxicity_endpoint,1327,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42190775 abstract/title reviewed; no clear in-scope renal/renal safety endpoint is grounded for significant.,2026-06-07T02:20:35+00:00
32174,toxicity_endpoint,1328,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42185680; 'p97/VCP as a dual regulator of UPS and autophagy in ovarian cancer: a novel therapeutic target.' does not provide a sufficiently specific administered-oligo toxicity endpoint for siRNA-mediated.,2026-06-07T02:20:35+00:00
32175,toxicity_endpoint,1329,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in single; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
32176,toxicity_endpoint,1330,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42156718; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for signaling.",2026-06-07T02:20:35+00:00
32177,toxicity_endpoint,1331,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42155048; no source passage or abstract wording gives a dependable toxicity call for siRNA-based.,2026-06-07T02:20:35+00:00
32178,toxicity_endpoint,1332,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42154661; 'Myocardial YBX1 is dispensable for cardiac development and function.' does not provide a sufficiently specific administered-oligo toxicity endpoint for YBX1.,2026-06-07T02:20:35+00:00
32179,toxicity_endpoint,1333,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42144579; 'IL-21 rs2055979 and serum IL-21 levels are associated with both non-segmental and segmental vi?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significantly.,2026-06-07T02:20:35+00:00
32180,toxicity_endpoint,1334,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42138477; significantly remains unsupported for renal/renal safety after abstract-level review of 'The sodium-glucose cotransporter 2 inhibitor empagliflozin reverses hyperglycemia-triggered va?'.,2026-06-07T02:20:35+00:00
32181,toxicity_endpoint,1335,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42136331; silencing remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Pan-Cancer Landscape of Thymine DNA Glycosylase and Its Potential Role in Lung Adenocarcinoma.'.,2026-06-07T02:20:35+00:00
32182,toxicity_endpoint,1336,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42132192; the abstained record was checked at abstract level, but general safety/systemic safety/tolerability is still not directly recoverable for inclisiran.",2026-06-07T02:20:35+00:00
32183,toxicity_endpoint,1337,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42116759; Signaling remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Aspirin (Acetylsalicylic Acid) Exerts Antineoplastic Effects on Bile Duct Carcinoma Cells Thro?'.,2026-06-07T02:20:35+00:00
32184,toxicity_endpoint,1338,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42107693; 'CircClint1/miR-378b/NPDC1 axis: A novel therapeutic target and biomarker for myocardial infarc?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significantly.,2026-06-07T02:20:35+00:00
32185,toxicity_endpoint,1339,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42106016; available abstract is not enough to curate hepatic/hepatotoxicity for signaling as a verified toxicity record.,2026-06-07T02:20:35+00:00
32186,toxicity_endpoint,1340,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42092626; the abstained record was checked at abstract level, but genotoxicity/DNA damage response is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
32187,toxicity_endpoint,1341,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42092489; 'HIV-1 Tat-induced VAPB disruption initiates a cascade of organellar failures culminating in ne?' does not provide a sufficiently specific administered-oligo toxicity endpoint for silencing.,2026-06-07T02:20:35+00:00
32188,toxicity_endpoint,1342,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42068681; available abstract is not enough to curate hepatic/hepatotoxicity for silences as a verified toxicity record.,2026-06-07T02:20:35+00:00
32189,toxicity_endpoint,1343,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 42034417; 'Nano-bioprotectant dsRsGH1@ε-PL@CMCS enhances RNAi efficacy against Rhizoctonia solani via dua?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significantly.,2026-06-07T02:20:35+00:00
32190,toxicity_endpoint,1344,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 42030890; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for signaling.",2026-06-07T02:20:35+00:00
32191,toxicity_endpoint,1345,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41996006 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for simple.,2026-06-07T02:20:35+00:00
32192,toxicity_endpoint,1346,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41980472; the abstained record was checked at abstract level, but general safety/systemic safety/tolerability is still not directly recoverable for signaling.",2026-06-07T02:20:35+00:00
32193,toxicity_endpoint,1347,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41946917 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for ANGPTL3.,2026-06-07T02:20:35+00:00
32194,toxicity_endpoint,1348,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41946126; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'TFEB has a protective effect in cisplatin induced AKI through regulating exosome-MVBs pathway.'.,2026-06-07T02:20:35+00:00
32195,toxicity_endpoint,1349,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41935388; significant remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Emerging Pharmacological Therapies in the Management of Hyperlipidemia.'.,2026-06-07T02:20:35+00:00
32196,toxicity_endpoint,1350,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41919975; 'Treatment advances for Duchenne muscular dystrophy.' does not provide a sufficiently specific administered-oligo toxicity endpoint for since.,2026-06-07T02:20:35+00:00
32197,toxicity_endpoint,1351,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41876745; Rejected: apoptosis and DNA-damage effects are cancer chemosensitization efficacy readouts, not safety/toxicity of the siRNA/LNP product.",2026-06-07T02:20:35+00:00
32198,toxicity_endpoint,1352,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41854123; no source passage or abstract wording gives a dependable toxicity call for Signaling.,2026-06-07T02:20:35+00:00
32199,toxicity_endpoint,1353,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41830315; 'Switching Long-Term Prophylaxis to Donidalorsen for Hereditary Angioedema: 1-Year OASISplus Re?' does not provide a sufficiently specific administered-oligo toxicity endpoint for Sixty-five.,2026-06-07T02:20:35+00:00
32200,toxicity_endpoint,1354,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41818942; the abstained record was checked at abstract level, but general safety/cell viability/cytotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
32201,toxicity_endpoint,1355,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41802598 abstract/title reviewed; no clear in-scope general safety/systemic safety/tolerability endpoint is grounded for site.,2026-06-07T02:20:35+00:00
32202,toxicity_endpoint,1356,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41780062; single-ascending-dose remains unsupported for general safety/systemic safety/tolerability after abstract-level review of 'Zorevunersen in Children and Adolescents with Dravet Syndrome.'.,2026-06-07T02:20:35+00:00
32203,toxicity_endpoint,1357,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41763165; 'Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates diabetic nephropath?' does not provide a sufficiently specific administered-oligo toxicity endpoint for silenced.,2026-06-07T02:20:35+00:00
32204,toxicity_endpoint,1358,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41709848; Rejected: passage reports antitumor efficacy and immune modulation for PD-L1 siRNA/resveratrol nanoparticles; adverse-event language refers to checkpoint inhibitors generally, not product toxicity.",2026-06-07T02:20:35+00:00
32205,toxicity_endpoint,1359,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41655546; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
32206,toxicity_endpoint,1360,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41629025; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
32207,toxicity_endpoint,1361,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41617458; available abstract is not enough to curate general safety/cell viability/cytotoxicity for siRNA-mediated as a verified toxicity record.,2026-06-07T02:20:35+00:00
32208,toxicity_endpoint,1362,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41611156; available abstract is not enough to curate hepatic/hepatotoxicity for significantly as a verified toxicity record.,2026-06-07T02:20:35+00:00
32209,toxicity_endpoint,1363,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41587381; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
32210,toxicity_endpoint,1364,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41575474; size remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'BMP7 attenuates myocardial injury and preserves cardiac function after myocardial infarction b?'.,2026-06-07T02:20:35+00:00
32211,toxicity_endpoint,1365,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41570782; no source passage or abstract wording gives a dependable toxicity call for significant.,2026-06-07T02:20:35+00:00
32212,toxicity_endpoint,1366,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41549423; available abstract is not enough to curate hepatic/hepatotoxicity for Sirtuin as a verified toxicity record.,2026-06-07T02:20:35+00:00
32213,toxicity_endpoint,1367,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41533526; available abstract is not enough to curate hepatic/hepatotoxicity for significant as a verified toxicity record.,2026-06-07T02:20:35+00:00
32214,toxicity_endpoint,1368,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41518406; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
32215,toxicity_endpoint,1369,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41512600; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
32216,toxicity_endpoint,1370,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41503700 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for silencing.,2026-06-07T02:20:35+00:00
32217,toxicity_endpoint,1371,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41468644; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Leveraging genomic conservation in emerging SARS-CoV-2 variants for precision diagnostics, vac?'.",2026-06-07T02:20:35+00:00
32218,toxicity_endpoint,1372,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41456811; no source passage or abstract wording gives a dependable toxicity call for siRNA-mediated.,2026-06-07T02:20:35+00:00
32219,toxicity_endpoint,1373,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41456525; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for signaling.",2026-06-07T02:20:35+00:00
32220,toxicity_endpoint,1374,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41412541; the abstained record was checked at abstract level, but general safety/systemic safety/tolerability is still not directly recoverable for significantly.",2026-06-07T02:20:35+00:00
32221,toxicity_endpoint,1375,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41211943; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for elebsiran.",2026-06-07T02:20:35+00:00
32222,toxicity_endpoint,1376,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41199668; simulated remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Glutathione-Depletable Nanoinducer for Boosting Immunomodulatory Synergistic Therapy to Revers?'.,2026-06-07T02:20:35+00:00
32223,toxicity_endpoint,1377,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41120778; available abstract is not enough to curate hepatic/hepatotoxicity for significant as a verified toxicity record.,2026-06-07T02:20:35+00:00
32224,toxicity_endpoint,1378,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41043722; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for single-cell.",2026-06-07T02:20:35+00:00
32225,toxicity_endpoint,1379,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41028674; no source passage or abstract wording gives a dependable toxicity call for nusinersen.,2026-06-07T02:20:35+00:00
32226,toxicity_endpoint,1380,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41028673; 'DG9-Conjugated Morpholino-Based Exon 51-Skipping Therapy for Duchenne Muscular Dystrophy.' does not provide a sufficiently specific administered-oligo toxicity endpoint for DG9-Conjugated.,2026-06-07T02:20:35+00:00
32227,toxicity_endpoint,1381,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40982237 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for lumasiran.,2026-06-07T02:20:35+00:00
32228,toxicity_endpoint,1382,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40957780; 'Transcatheter closure of ostium secundum atrial septal defects in 2253 children and adults: Ea?' does not provide a sufficiently specific administered-oligo toxicity endpoint for since.,2026-06-07T02:20:35+00:00
32229,toxicity_endpoint,1383,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40840061 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for site-specific.,2026-06-07T02:20:35+00:00
32230,toxicity_endpoint,1384,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40816607; available abstract is not enough to curate hepatic/hepatotoxicity for single as a verified toxicity record.,2026-06-07T02:20:35+00:00
32231,toxicity_endpoint,1385,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39916530 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for Site.,2026-06-07T02:20:35+00:00
32232,toxicity_endpoint,1386,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41124364 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for silencing.,2026-06-07T02:20:35+00:00
32233,toxicity_endpoint,1387,human_recuration_v2,apply_recuration_verdicts.py,curator_verified,accept,ni_jie,"Accept B: PubMed abstract gives a direct abstract-level signal for hepatic/hepatotoxicity in siRNA; no full passage, so curator kept confidence limited.",2026-06-07T02:20:35+00:00
32234,toxicity_endpoint,1388,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40954399; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for since.",2026-06-07T02:20:35+00:00
32235,toxicity_endpoint,1389,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40772591; Rejected: ferroptosis/immunogenic cell death and antitumor efficacy in colon cancer are excluded cancer-cell-killing efficacy endpoints, not safety/toxicity.",2026-06-07T02:20:35+00:00
32236,toxicity_endpoint,1390,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 39919854 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for single-stranded.,2026-06-07T02:20:35+00:00
32237,toxicity_endpoint,1391,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40383157 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA.,2026-06-07T02:20:35+00:00
32238,toxicity_endpoint,1392,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40637307; significantly remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Targeting V-ATPase subunits via RNA interference disrupts ultrastructural and normal life acti?'.,2026-06-07T02:20:35+00:00
32239,toxicity_endpoint,1393,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40600720; no source passage or abstract wording gives a dependable toxicity call for siRNA.,2026-06-07T02:20:35+00:00
32240,toxicity_endpoint,1394,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40576350; available abstract is not enough to curate hepatic/hepatotoxicity for silences as a verified toxicity record.,2026-06-07T02:20:35+00:00
32241,toxicity_endpoint,1395,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40480693 abstract/title reviewed; no clear in-scope renal/renal safety endpoint is grounded for side.,2026-06-07T02:20:35+00:00
32242,toxicity_endpoint,1396,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40163299; available abstract is not enough to curate hepatic/hepatotoxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
32243,toxicity_endpoint,1397,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40103484; 'Peptide-Oligonucleotide Nanohybrids Designed for Precise Gene Therapy of Rheumatoid Arthritis.' does not provide a sufficiently specific administered-oligo toxicity endpoint for signaling.,2026-06-07T02:20:35+00:00
32244,toxicity_endpoint,1398,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40028836; the abstained record was checked at abstract level, but general safety/systemic safety/tolerability is still not directly recoverable for siRNA-Based.",2026-06-07T02:20:35+00:00
32245,toxicity_endpoint,1399,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41135269; significant remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'miR-31a-5p targeting Crebbp suppresses Wnt/β-catenin and TGF-β pathways to alleviate oil mist?'.,2026-06-07T02:20:35+00:00
32246,toxicity_endpoint,1400,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41115043; no source passage or abstract wording gives a dependable toxicity call for Signaling.,2026-06-07T02:20:35+00:00
32247,toxicity_endpoint,1401,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 41101071; the abstained record was checked at abstract level, but general toxicity/toxicity is still not directly recoverable for SIRT1-mediated.",2026-06-07T02:20:35+00:00
32248,toxicity_endpoint,1402,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41086680; available abstract is not enough to curate general toxicity/toxicity for siRNA as a verified toxicity record.,2026-06-07T02:20:35+00:00
32249,toxicity_endpoint,1403,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 41017094 abstract/title reviewed; no clear in-scope general toxicity/toxicity endpoint is grounded for siRNA-mediated.,2026-06-07T02:20:35+00:00
32250,toxicity_endpoint,1404,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40934697; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significance.",2026-06-07T02:20:35+00:00
32251,toxicity_endpoint,1405,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40925436; 'Single-cell and spatial transcriptomics identify dihydrolipoic acid succinyltransferase as a p?' does not provide a sufficiently specific administered-oligo toxicity endpoint for Single-cell.,2026-06-07T02:20:35+00:00
32252,toxicity_endpoint,1406,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40888739 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for olezarsen.,2026-06-07T02:20:35+00:00
32253,toxicity_endpoint,1407,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40884558; inclisiran remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Inclisiran-based treatment strategy in hypercholesterolaemia: the VICTORION-Difference trial.'.,2026-06-07T02:20:35+00:00
32254,toxicity_endpoint,1408,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40840404; available abstract is not enough to curate hepatic/hepatotoxicity for Single-cell as a verified toxicity record.,2026-06-07T02:20:35+00:00
32255,toxicity_endpoint,1409,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40839797; unspecified CpG oligodeoxynucleotide remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Needle-Free Transdermal Patch for Influenza Vaccination.'.,2026-06-07T02:20:35+00:00
32256,toxicity_endpoint,1410,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40839167; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for signaling.",2026-06-07T02:20:35+00:00
32257,toxicity_endpoint,1411,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40816424; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for siRNA.",2026-06-07T02:20:35+00:00
32258,toxicity_endpoint,1412,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40772726; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for silence.",2026-06-07T02:20:35+00:00
32259,toxicity_endpoint,1413,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40753527; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for simulate.",2026-06-07T02:20:35+00:00
32260,toxicity_endpoint,1414,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40752151; 'Mono(2-ethylhexyl) phthalate impairs synaptic structure via altering long non-coding RNA MALAT?' does not provide a sufficiently specific administered-oligo toxicity endpoint for significant.,2026-06-07T02:20:35+00:00
32261,toxicity_endpoint,1415,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40706921; Rejected: miR-130b endogenous ncRNA nanovesicle for obesity is excluded; reported weight/organ-weight changes are pharmacodynamic efficacy rather than oligo toxicity.,2026-06-07T02:20:35+00:00
32262,toxicity_endpoint,1416,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40679654 abstract/title reviewed; no clear in-scope renal/renal safety endpoint is grounded for situ.,2026-06-07T02:20:35+00:00
32263,toxicity_endpoint,1417,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40673861; 'Donidalorsen Treatment of Hereditary Angioedema in Patients Previously on Long-Term Prophylaxi?' does not provide a sufficiently specific administered-oligo toxicity endpoint for NCT05392114.,2026-06-07T02:20:35+00:00
32264,toxicity_endpoint,1418,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40670197; 'Insights from a real-world experience with inclisiran at a large United States lipid clinic.' does not provide a sufficiently specific administered-oligo toxicity endpoint for inclisiran.,2026-06-07T02:20:35+00:00
32265,toxicity_endpoint,1419,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40643013; available abstract is not enough to curate renal/renal safety for simplification as a verified toxicity record.,2026-06-07T02:20:35+00:00
32266,toxicity_endpoint,1420,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40637829 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for significant.,2026-06-07T02:20:35+00:00
32267,toxicity_endpoint,1421,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40632359; no source passage or abstract wording gives a dependable toxicity call for signaling.,2026-06-07T02:20:35+00:00
32268,toxicity_endpoint,1422,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40619262; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for significance.",2026-06-07T02:20:35+00:00
32269,toxicity_endpoint,1423,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40609497; 'Cadmium exposure triggers vimentin phosphorylation via SIRT6-regulated AKT/PI3K signaling path?' does not provide a sufficiently specific administered-oligo toxicity endpoint for SIRT6-regulated.,2026-06-07T02:20:35+00:00
32270,toxicity_endpoint,1424,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40550345 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for siRNA-mediated.,2026-06-07T02:20:35+00:00
32271,toxicity_endpoint,1425,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,"Reject: PMID 40501349; the abstained record was checked at abstract level, but hepatic/hepatotoxicity is still not directly recoverable for Signaling.",2026-06-07T02:20:35+00:00
32272,toxicity_endpoint,1426,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40470916; available abstract is not enough to curate hepatic/hepatotoxicity for significance as a verified toxicity record.,2026-06-07T02:20:35+00:00
32273,toxicity_endpoint,1427,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40456494; siHIF- remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'siHIF-1α-loaded micellar nanoparticles inhibit M1 macrophage activation to ameliorate chronic?'.,2026-06-07T02:20:35+00:00
32274,toxicity_endpoint,1428,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40424981; no source passage or abstract wording gives a dependable toxicity call for significantly.,2026-06-07T02:20:35+00:00
32275,toxicity_endpoint,1429,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40399040; no source passage or abstract wording gives a dependable toxicity call for simplification.,2026-06-07T02:20:35+00:00
32276,toxicity_endpoint,1430,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40368359 abstract/title reviewed; no clear in-scope general safety/systemic safety/tolerability endpoint is grounded for similar.,2026-06-07T02:20:35+00:00
32277,toxicity_endpoint,1431,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40350233 abstract/title reviewed; no clear in-scope general safety/systemic safety/tolerability endpoint is grounded for unspecified siRNA.,2026-06-07T02:20:35+00:00
32278,toxicity_endpoint,1432,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40311394 abstract/title reviewed; no clear in-scope general safety/systemic safety/tolerability endpoint is grounded for nusinersen.,2026-06-07T02:20:35+00:00
32279,toxicity_endpoint,1433,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40298147 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for signaling.,2026-06-07T02:20:35+00:00
32280,toxicity_endpoint,1434,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40274035; unspecified ASO remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Development and optimization of an antibody-free nucleic acid lateral flow assay (AF-NALFA) as?'.,2026-06-07T02:20:35+00:00
32281,toxicity_endpoint,1435,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40239402; siRNA remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Hybride nanoparticles composed of SN38-modified [12]aneN(3) and biotinylated lipids for target?'.,2026-06-07T02:20:35+00:00
32282,toxicity_endpoint,1436,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40187509; situ remains unsupported for hepatic/hepatotoxicity after abstract-level review of 'Transseptal puncture for catheter ablation of atrial fibrillation in patients with septal occl?'.,2026-06-07T02:20:35+00:00
32283,toxicity_endpoint,1437,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40162643 abstract/title reviewed; no clear in-scope hepatic/hepatotoxicity endpoint is grounded for site.,2026-06-07T02:20:35+00:00
32284,toxicity_endpoint,1438,human_recuration_v2,apply_recuration_verdicts.py,recurated_rejected,reject,ni_jie,Reject: PMID 40158211; no source passage or abstract wording gives a dependable toxicity call for single-ascending-dose.,2026-06-07T02:20:35+00:00
32285,curation_candidate,38323,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is background/tool introduction for SeedMatchR with no specific observed off-target measurement."", ""grounding_quote"": """", ""source_pmid"": ""38192001"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.348366+00:00
32286,offtarget_evidence,535,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""All gates pass: siRNA modification is tested and observed to suppress seed-region off-target activity."", ""grounding_quote"": ""the siRNAs with different sequences incorporating 2′-formamidonucleoside with four kinds of nucleobases into any position other than 2nd position in the seed region revealed a significant suppression of off-target activity while maintaining on-target RNAi activity"", ""source_pmid"": ""39231537"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.363916+00:00
32287,curation_candidate,38407,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports intended multigene ASO knockdown and efficacy, not an unintended off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41732207"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32288,offtarget_evidence,536,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""All gates pass: therapeutic CpG oligonucleotides show an observed unintended suppression of cGAS signaling."", ""grounding_quote"": ""Unexpectedly, we found that class A ODNs suppress the cGAS level and downstream signaling in human and murine FRC."", ""source_pmid"": ""40337520"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32289,curation_candidate,38413,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports DNAsome-siRNA delivery, target knockdown, and cytotoxicity/safety assays, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""39906612"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32290,curation_candidate,38414,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports STAT3 inhibition and mismatch-repair tumor context, not oligo hybridization off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""39886125"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32291,curation_candidate,38440,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports PK/tissue-distribution assay methodology, not an observed off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""29022758"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32292,curation_candidate,38476,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports safety and pharmacokinetics of SRN001, not an off-target result."", ""grounding_quote"": """", ""source_pmid"": ""42052104"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32293,curation_candidate,38482,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: spittlebug transcriptomics/agricultural biology passage has no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""41491413"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32294,curation_candidate,38489,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: agricultural insect RNAi pest-control study is excluded and does not report therapeutic oligo off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""42042481"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32295,curation_candidate,38494,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: ASO here is an author-reflection/title artifact; passage is colon-cancer transcriptomics with no therapeutic oligo agent."", ""grounding_quote"": """", ""source_pmid"": ""39645556"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32296,curation_candidate,38498,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage describes computational feature engineering for off-target prediction, not an observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""40725043"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32297,curation_candidate,38502,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports CNS delivery, gene silencing, and toxicity absence, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""41473322"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32298,curation_candidate,38508,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports allele-specific target knockdown and delivery-vector cytotoxicity, not unintended off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""39934917"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32299,curation_candidate,38510,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: plant RNAi transgenic wheat study is agricultural/research-tool biology, not a therapeutic oligo under study."", ""grounding_quote"": """", ""source_pmid"": ""41669362"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32300,curation_candidate,38512,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: shRNA-recombinant Chlorella mosquito-control agent is excluded and is not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""41088451"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32301,curation_candidate,38532,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports siRNA conjugate synthesis and delivery/endosomal escape, not an observed off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""39464033"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32302,curation_candidate,38535,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports GapmeR nanoparticle delivery, bone activity, and toxicity checks, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""39588258"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32303,curation_candidate,38538,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: oligo silencing is used as a research knockdown tool to model Parkinson disease, not as a therapeutic being characterized."", ""grounding_quote"": """", ""source_pmid"": ""37644186"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32304,curation_candidate,38543,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review/background passage discusses RNAi antiviral prospects and hurdles, with no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""39339965"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32305,curation_candidate,38557,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: vector-expressed shRNA/miRNA cell-engineering platform is excluded and not a therapeutic oligo safety/off-target study."", ""grounding_quote"": """", ""source_pmid"": ""37799328"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.364917+00:00
32306,offtarget_evidence,537,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""All gates pass: the passage reports seed-mediated siRNA suppression of unintended mRNAs."", ""grounding_quote"": ""siRNA also suppresses the expression of unintended mRNAs with partially complementary sequences mainly within the siRNA seed region"", ""source_pmid"": ""35205363"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32307,curation_candidate,38586,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: Oligo-FISH probe-design review concerns research probes, not therapeutic oligonucleotides."", ""grounding_quote"": """", ""source_pmid"": ""34281175"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32308,curation_candidate,38958,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports ASO chemistry effects on activity, immune stimulation, and cytotoxicity, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""34417625"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32309,curation_candidate,38970,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports ASO delivery and antitumor efficacy with nCVTs, not an unintended off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41399312"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32310,curation_candidate,38979,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports ASO neurotoxicity and chemical modification mitigation, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""41467114"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32311,curation_candidate,38981,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports renal efficacy, glucosuria, liver damage, and distribution, not an off-target result."", ""grounding_quote"": """", ""source_pmid"": ""39850319"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32312,curation_candidate,38999,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage summarizes ASO chemistry and delivery challenges without primary off-target measurements."", ""grounding_quote"": """", ""source_pmid"": ""39653607"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32313,curation_candidate,39004,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review/background passage on endocrine ASO/RNAi therapy has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""39944202"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32314,curation_candidate,39008,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports intended multitarget circASO silencing and stability, not unintended off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40747042"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32315,curation_candidate,39012,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports engineered on-target mRNA degradation via lysosomal trafficking, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""40547092"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32316,curation_candidate,39017,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review/background passage on alopecia ASO potential has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""40181256"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32317,curation_candidate,39027,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports molecular-dynamics/design simulations of ASO-RNA binding, not observed off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""39494149"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.366422+00:00
32318,curation_candidate,39031,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports anti-PCDHA11 ASO efficacy and pathway effects; off-target is only a screening criterion, not an observed result."", ""grounding_quote"": """", ""source_pmid"": ""39304746"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32319,curation_candidate,39050,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: consensus/review-style safety assessment discussion has no primary observed off-target result in this excerpt."", ""grounding_quote"": """", ""source_pmid"": ""36579950"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32320,curation_candidate,39072,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review/background passage describes ASO specificity in general, not a measured off-target observation."", ""grounding_quote"": """", ""source_pmid"": ""35056851"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32321,curation_candidate,39075,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports platelet activation and thrombocytopenia mechanisms, which are toxicity endpoints, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""33567808"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32322,curation_candidate,39081,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports chemistry-driven hepatotoxicity and potency changes, not an observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""34141070"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32323,curation_candidate,39083,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports tolerability/adverse-event outcomes for 2MOE ASOs, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""34242101"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32324,curation_candidate,39085,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports ASO effects on platelet activation/aggregation and thrombosis risk, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""33540294"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32325,curation_candidate,39093,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage asserts targeted specificity/therapeutic potency but does not report an unintended off-target measurement."", ""grounding_quote"": """", ""source_pmid"": ""33288723"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32326,curation_candidate,39096,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports ASO corneal delivery and MALAT1 knockdown, not an off-target result."", ""grounding_quote"": """", ""source_pmid"": ""32202944"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32327,curation_candidate,39106,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage summarizes receptor-mediated uptake of PS ASOs without primary off-target data."", ""grounding_quote"": """", ""source_pmid"": ""29425080"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32328,curation_candidate,39117,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports iontophoretic ASO delivery, bioavailability, and edema/safety, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""28375679"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32329,curation_candidate,39122,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports integrated safety endpoints including complement and platelets, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""27357629"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32330,curation_candidate,39154,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage discusses lessons from nusinersen off-target effects but gives no primary observed result in this excerpt."", ""grounding_quote"": """", ""source_pmid"": ""42149739"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32331,curation_candidate,39166,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage summarizes siRNA animal-model efficacy studies, not primary off-target measurements."", ""grounding_quote"": """", ""source_pmid"": ""41596367"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32332,curation_candidate,39170,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage on siRNA therapeutics in IBD has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41852626"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.367430+00:00
32333,curation_candidate,39195,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports designed ASO control of synthetic mRNA translation; off-target effects are only a motivation."", ""grounding_quote"": """", ""source_pmid"": ""41210590"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32334,curation_candidate,39200,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports ASO-Sort1 therapeutic efficacy and proteomics, not unintended off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""40501380"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32335,curation_candidate,39219,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage on cancer oligonucleotide applications mentions off-target challenges but no primary observed result."", ""grounding_quote"": """", ""source_pmid"": ""40045578"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32336,curation_candidate,39222,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports allele-specific cancer-cell killing and AAV vector toxicity, not oligo off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""40800004"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32337,curation_candidate,39223,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage on polymer-assisted ASO delivery has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""40166479"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32338,curation_candidate,39224,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports bioanalytical quantification of siRNA strands, not an off-target result."", ""grounding_quote"": """", ""source_pmid"": ""39886752"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32339,curation_candidate,39228,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage on aptamer strategies and clay delivery has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41053953"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32340,curation_candidate,39230,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports in-silico siRNA design and off-target filtration, not observed off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""40877400"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32341,curation_candidate,39233,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports ultrasound-responsive siRNA brain delivery, not an observed off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""40582054"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32342,curation_candidate,39234,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: CRISPR/Cas9 control by modified oligonucleotides is excluded from therapeutic oligo off-target curation."", ""grounding_quote"": """", ""source_pmid"": ""40363763"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32343,curation_candidate,39238,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: perspective/review passage on oligo stability and delivery has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""39772535"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32344,curation_candidate,39239,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports albumin/ultrasound ASO delivery and silencing assays, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""39967271"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32345,curation_candidate,39259,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: literature review/survey of first-in-human oligonucleotide studies, not a primary off-target result."", ""grounding_quote"": """", ""source_pmid"": ""39311689"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32346,curation_candidate,39273,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports intended splice-blocking efficacy and lack of toxicity, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""38276948"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32347,curation_candidate,39277,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports transfection-agent delivery and cytotoxicity, not an observed off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""38672408"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32348,curation_candidate,39291,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports siRNA chemistry effects on potency/safety, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""36725319"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32349,curation_candidate,39304,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage on liposomal ASO delivery has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""37242677"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32350,curation_candidate,39320,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review passage on TFO/PNA genome-targeting tools has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""37896275"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32351,curation_candidate,39340,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports an intrathecal administration method and CNS distribution/silencing, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""35213030"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32352,curation_candidate,39346,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review/background passage on ASO liver therapy has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""36569303"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.368431+00:00
32353,curation_candidate,39360,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports on-target TGF-beta-RII knockdown and neurogenic efficacy/tox program, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""33860461"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.369434+00:00
32354,curation_candidate,39372,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports 2-F-NMC siRNA chemistry and RNAi potency, not an observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""33577685"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.369434+00:00
32355,offtarget_evidence,538,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""All gates pass: antisense 2'-MOE gapmers were experimentally assessed and showed minimal off-target activity."", ""grounding_quote"": ""Using immortalized patient-derived muscle cells and local intramuscular injections in the FLExDUX4 FSHD mouse model, we showed that our designed 2′-MOE gapmers significantly reduced DUX4 transcript levels in vitro and in vivo, respectively. Furthermore, in vitro, we observed significantly reduced expression of DUX4-activated downstream targets, restoration of FSHD signature genes by RNA sequencing, significant improvements in myotube morphology, and minimal off-target activity."", ""source_pmid"": ""33068777"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32356,curation_candidate,39392,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports polymeric ASO delivery, exon-skipping, and cytotoxicity, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""32070342"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32357,curation_candidate,39393,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports synthesis and physicochemical properties of boron-cluster oligo conjugates, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""33375375"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32358,curation_candidate,39407,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports peptide-PMO delivery and therapeutic correction/specificity, not an unintended off-target result."", ""grounding_quote"": """", ""source_pmid"": ""31479430"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32359,curation_candidate,39408,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports nanoparticle formulation stability, functionality, and biocompatibility, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""31140918"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32360,curation_candidate,39421,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports renal safety outcomes for 2MOE ASOs, which are toxicity endpoints, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""29185862"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32361,curation_candidate,39434,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports PMO delivery/exon-skipping and toxicity checks, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""28633548"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32362,curation_candidate,39436,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports GalNAc-siRNA stability, PK/PD, liver exposure, and silencing, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""28981809"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32363,curation_candidate,39442,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: review/mechanism overview of RNA therapeutics has no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""27570789"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32364,curation_candidate,39483,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: morpholino oligos are used as zebrafish research knockdown tools for developmental toxicology, not as therapeutic oligonucleotides under off-target characterization."", ""grounding_quote"": """", ""source_pmid"": ""22669659"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32365,curation_candidate,39573,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: passage reports bottlebrush-polymer ASO delivery and target knockdown, not an observed unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""42182416"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32366,curation_candidate,39582,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: dsRNA/LNP work is agricultural insect RNAi for fall armyworm control, which is excluded from therapeutic oligonucleotide scope."", ""grounding_quote"": """", ""source_pmid"": ""41970227"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32367,curation_candidate,39584,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: narrative literature summary of siRNA chemotherapy co-delivery and efficacy, with no primary observed unintended off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41929569"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32368,curation_candidate,39587,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: narrative review mentions off-target effects only as a general delivery challenge, with no observed off-target measurement."", ""grounding_quote"": """", ""source_pmid"": ""41899235"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32369,curation_candidate,39591,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: passage is background/current-work framing about oligonucleotide design and possible protein/immune interactions, not a primary off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41614678"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.371957+00:00
32370,curation_candidate,39597,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of siRNA delivery architectures for osteoarthritis, with no primary observed off-target measurement."", ""grounding_quote"": """", ""source_pmid"": ""41993699"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32371,curation_candidate,39605,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: excerpt is breast-cancer treatment background and contains no therapeutic oligonucleotide primary off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41755009"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32372,curation_candidate,39619,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: passage contains only an authorship note and no in-scope oligonucleotide or primary off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""41923983"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32373,curation_candidate,39622,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: excerpt is extracellular-vesicle biology background and does not present a therapeutic oligonucleotide under study."", ""grounding_quote"": """", ""source_pmid"": ""41891990"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32374,curation_candidate,39630,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: excerpt is chronic lung inflammation background and contains no oligonucleotide agent or primary off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41754897"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32375,curation_candidate,39641,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: dendrimer-siRNA binding/affinity characterization concerns delivery complex formation, not an unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""41640357"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32376,curation_candidate,39661,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: passage reports nanozyme activity and siHmox1 therapeutic design for heart failure, not observed off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""41477663"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32377,curation_candidate,39662,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of oral siRNA nanodelivery platforms without a primary observed unintended off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41351306"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32378,curation_candidate,39672,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: dsRNA production is for agricultural RNAi-based biopesticide development in an insect pest, outside therapeutic oligonucleotide scope."", ""grounding_quote"": """", ""source_pmid"": ""42188119"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32379,curation_candidate,39679,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: passage concerns endogenous RNAi and heterochromatin biology in yeast, not a therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""41910327"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32380,curation_candidate,39695,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: siRNA/shRNA is used to induce UBE3A expression and assess target/neighbouring genes, but no observed unintended off-target effect is reported."", ""grounding_quote"": """", ""source_pmid"": ""41751540"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32381,curation_candidate,39700,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: CMV-loaded siTNF-alpha shows delivery, anti-inflammatory activity, and low cytotoxicity, not an off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""41633581"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32382,curation_candidate,39703,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: cholesterol effects on siRNA trafficking, endosomal escape, and gene silencing are delivery/efficacy findings, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""41564596"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32383,curation_candidate,39713,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: excerpt is a review of endogenous plant coding-transcript-derived siRNAs, not therapeutic oligonucleotide evidence."", ""grounding_quote"": """", ""source_pmid"": ""41751838"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32384,curation_candidate,39715,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: ASO passage reports pharmacokinetics, CNS penetration, safety, and efficacy rather than unintended off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40654713"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32385,curation_candidate,39716,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: GalNAc-RBC extracellular vesicles loaded with ASO/siRNA are evaluated for delivery and therapy, not off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""40692538"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32386,curation_candidate,39736,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: review mentions off-target binding and toxicity as general barriers, with no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""40981427"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32387,curation_candidate,39738,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: passage describes an LC-MS/MS quantification method for antibody-siRNA conjugates, not off-target biology."", ""grounding_quote"": """", ""source_pmid"": ""40888416"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32388,curation_candidate,39742,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: RNA cancer immunotherapy review discusses off-target minimization as a challenge, not an observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""40615758"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32389,curation_candidate,39746,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: multimeric GalNAc-siRNA scaffold work reports delivery and silencing activity, not unintended off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40443118"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32390,curation_candidate,39752,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: LNA gapmer ASO findings are target knockdown and antitumor efficacy, not an observed off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""39988873"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32391,curation_candidate,39756,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: AuNC-siRNA work reports delivery, cytotoxicity, oxidative stress, and cell-cycle assays, which are toxicity/delivery endpoints rather than off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""41439881"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32392,curation_candidate,39757,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: DsiRNA wound dressing passage reports efficacy and 28-day toxicity, not an unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""40911569"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32393,curation_candidate,39759,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: excerpt is author/conflict metadata plus STAT3 decoy background, with no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""40882634"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32394,curation_candidate,39764,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: aminoglycoside adjuvants enhance LNP-siRNA delivery and lysosomal escape and report hemolysis, not off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""41244463"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.372952+00:00
32395,curation_candidate,39773,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: LNP-siRNA/gentamicin passage reports endosomal escape and EGFR silencing, not an observed off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""40487122"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32396,curation_candidate,39782,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: AAV vector and siRNA are used as disease-mechanism manipulation tools in a myopia model, not therapeutic oligonucleotide off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""40862775"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32397,curation_candidate,39786,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: exosome siBTK/isoimperatorin passage reports targeted delivery, anti-lymphoma activity, and biosafety, not off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""41625362"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32398,curation_candidate,39789,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: excerpt is breast-cancer/photothermal-therapy background and contains no siRNA off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41599118"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32399,curation_candidate,39791,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: siRNA design review mentions preventing off-target RNAi but provides no observed unintended off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41476668"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32400,curation_candidate,39792,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: HCC/RNAi excerpt is background and therapeutic-efficacy framing, not primary off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""41471333"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32401,curation_candidate,39807,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: passage is only a retraction notice and contains no in-scope therapeutic oligonucleotide result."", ""grounding_quote"": """", ""source_pmid"": ""41287763"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32402,curation_candidate,39815,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: biomimetic liposome co-delivers siRNAs for tumor targeting and antitumor efficacy, not off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""41146666"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32403,curation_candidate,39823,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: helicene-squalene nanovectors deliver siRNA to mitochondria for target silencing, not off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""41055836"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32404,curation_candidate,39829,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: excerpt is Alzheimer disease and BBB background without a primary siRNA off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41007671"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32405,curation_candidate,39833,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: Dio/siICAM-1 nanoparticle work reports neutrophil targeting, delivery, and inflammatory cytokine effects, not off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40977834"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32406,curation_candidate,39835,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: NLE platform co-delivers MUC1 mRNA and CTLA-4 siRNA for immune efficacy, not unintended off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""40943370"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32407,curation_candidate,39840,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: alkenyl-alanine peptides improve siRNA encapsulation, uptake, gene silencing, and biodistribution, not off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""40915857"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32408,curation_candidate,39850,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: albumin-binding siRNAs show tumor delivery, IRS2 on-target silencing, and tumor-growth reduction, not unintended off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40766531"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32409,curation_candidate,39852,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: DNA Soccer Framework improves siRNA delivery and Bcl2L12 silencing/apoptosis, not off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40747059"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32410,curation_candidate,39860,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: HA-anchored Fe-MOF co-delivery reports macrophage targeting, inflammatory-factor reduction, ROS reduction, and M2 polarization, not off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""40688667"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32411,curation_candidate,39863,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: ocular nanovesicles deliver Caspase-2 siRNA for gene silencing and apoptosis reduction, not off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40681573"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32412,curation_candidate,39867,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: cetuximab-starch siRNA complexes show uptake, on-target knockdown, and tumor accumulation, not unintended off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""40666030"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32413,curation_candidate,39886,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: LNP composition and His10 incorporation improve siRNA silencing efficiency and stability, not off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40366254"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32414,curation_candidate,39889,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: engineered exosomes co-deliver BACE1 siRNA and berberine for Alzheimer therapy, not off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""40351705"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32415,curation_candidate,39900,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: engineered platelets deliver p53 siRNA for target suppression and AKI attenuation, not unintended off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40156015"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32416,curation_candidate,39907,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: GRP78-targeting peptides mediate siRNA delivery and GRP78 knockdown outcomes, not off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""39967318"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32417,curation_candidate,39916,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of nanocarrier siRNA delivery for TBI/AD without primary observed off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""39314170"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32418,curation_candidate,39917,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: DNA cube platform reports brain delivery and ASO target-gene downregulation, not unintended off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""39092676"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32419,curation_candidate,39929,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: review of RNAi nanocarriers and delivery/safety profiles, with no observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""41304838"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32420,curation_candidate,39940,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: endogenous RNAi-capable yeast lncRNA biology is outside therapeutic oligonucleotide scope."", ""grounding_quote"": """", ""source_pmid"": ""41027714"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32421,curation_candidate,39944,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: allele-specific siRNA deliberately silences mutant PACS1 while sparing wild-type mRNA; this is intended specificity, not an unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""40972577"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32422,curation_candidate,39951,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: recNANPs conditionally release RNAi in diseased cells and achieve gene silencing, not observed off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40852577"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32423,curation_candidate,39961,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: RNAi delivery is for biopesticide use in Spodoptera frugiperda, an excluded agricultural/insect RNAi setting."", ""grounding_quote"": """", ""source_pmid"": ""40640142"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32424,curation_candidate,39962,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: si-NLRP3/control siRNA is used as a mechanistic knockdown tool in a toxin-induced neurotoxicity model, not a therapeutic oligonucleotide under off-target characterization."", ""grounding_quote"": """", ""source_pmid"": ""40625690"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32425,curation_candidate,39966,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: protein nanocage review claims reduced off-target effects but gives no primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""40573984"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32426,curation_candidate,39974,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: AAV-expressed shRNA gene therapy is excluded from therapeutic oligonucleotide scope."", ""grounding_quote"": """", ""source_pmid"": ""40437755"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32427,curation_candidate,39980,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: LNA gapmer ASO passage reports receptor-targeted delivery and antitumor efficacy, not observed off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""40177867"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.373951+00:00
32428,curation_candidate,39982,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: WRAP nanoparticles are evaluated for pH-sensitive siRNA delivery and FADD knockdown, not off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""40084851"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32429,curation_candidate,39994,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: RNAi transgenic cotton environmental safety study is agricultural RNAi and excluded from therapeutic oligonucleotide scope."", ""grounding_quote"": """", ""source_pmid"": ""41007318"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32430,curation_candidate,40001,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/3 fail: human AGO-siRNA complex is a biochemical mechanism study, not a therapeutic oligonucleotide off-target result."", ""grounding_quote"": """", ""source_pmid"": ""40240484"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32431,curation_candidate,40005,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: zilebesiran review reports pharmacology and blood-pressure efficacy from trials, not an observed off-target effect in this passage."", ""grounding_quote"": """", ""source_pmid"": ""40110301"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32432,curation_candidate,40008,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: excerpt is Parkinson disease background and contains no therapeutic siRNA result or off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""40006609"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32433,curation_candidate,40020,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: CMOL delivers siRNAs to downregulate survivin and enhance radiotherapy, which is on-target efficacy rather than off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""39535730"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32434,curation_candidate,40023,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: shRNA-mediated PD-1 knockdown in CAR-T cells is an excluded vector/cell-therapy construct, not an oligonucleotide therapeutic row."", ""grounding_quote"": """", ""source_pmid"": ""41234867"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32435,curation_candidate,40043,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: nanoparticle siRNA delivery review mentions off-target effects as background challenges, not observed unintended effects."", ""grounding_quote"": """", ""source_pmid"": ""38204162"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32436,curation_candidate,40044,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO in this passage means arteriosclerosis obliterans, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""39495988"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32437,curation_candidate,40059,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO is a journal/article-series acronym in a sentinel lymph node surgery reflection, not antisense oligonucleotide evidence."", ""grounding_quote"": """", ""source_pmid"": ""39313728"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32438,curation_candidate,40076,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: lipopolymer siRNA nanoparticles inhibit STAT5A for leukemia efficacy, not unintended off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""39296267"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32439,curation_candidate,40080,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: UDCA-conjugated ASO/exosomes are evaluated for intestinal permeation and exon skipping, not off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""39204368"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32440,curation_candidate,40081,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: oleyl-WRH peptides are evaluated for siRNA uptake, stability, and STAT3 silencing, not off-target activity."", ""grounding_quote"": """", ""source_pmid"": ""39204188"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32441,curation_candidate,40084,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: mismatch conversion evaluates designed cross-species on-target siRNA potency/efficacy, not unintended off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""39189114"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32442,curation_candidate,40100,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports siRNA lung delivery and gene silencing, not an observed unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""38126895"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32443,curation_candidate,40125,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: agent is AAV9-delivered shRNA, which is excluded; no oligonucleotide off-target result."", ""grounding_quote"": """", ""source_pmid"": ""38509093"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32444,curation_candidate,40126,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: ASO treatment is evaluated for on-target disease/oligodendrocyte effects, not unintended off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""38429929"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32445,curation_candidate,40138,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports computational siRNA efficacy prediction and validation, not observed off-target biology."", ""grounding_quote"": """", ""source_pmid"": ""39503523"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32446,curation_candidate,40143,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports siRNA polyplex assembly/delivery structure, not an unintended off-target result."", ""grounding_quote"": """", ""source_pmid"": ""39592142"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32447,curation_candidate,40148,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports targeted siRNA delivery, antitumor effects, biodistribution, and side-effect reduction, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""39431993"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32448,curation_candidate,40149,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports nose-to-brain delivery and AD efficacy endpoints, not an observed unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""39408684"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32449,curation_candidate,40158,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports siRNA delivery, biodistribution, and therapeutic AAA effects, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""39118143"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32450,curation_candidate,40162,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a review-style delivery overview for siRNA therapeutics, not a primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""39062852"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32451,curation_candidate,40165,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports nanocarrier loading/release and delivery behavior, not observed off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""38962028"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32452,curation_candidate,40203,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports ASO antitumor efficacy and no side effects; the row is not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""37185731"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32453,curation_candidate,40205,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports pharmacokinetics and safety of HSP47 siRNA LNP, not observed off-target biology."", ""grounding_quote"": """", ""source_pmid"": ""37654022"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32454,curation_candidate,40219,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports peptide-mediated siRNA binding/delivery/knockdown, not an unintended off-target result."", ""grounding_quote"": """", ""source_pmid"": ""37963105"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32455,curation_candidate,40220,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: antisense RNA is plasmid/Salmonella-delivered rather than an oligonucleotide therapeutic; no off-target result is reported."", ""grounding_quote"": """", ""source_pmid"": ""37941832"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32456,curation_candidate,40236,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is review/in-silico COVID-19 siRNA design background, not a primary observed off-target measurement."", ""grounding_quote"": """", ""source_pmid"": ""36814718"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32457,curation_candidate,40258,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports AuNP siRNA delivery and target knockdown, not unintended off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""37110552"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32458,curation_candidate,40268,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: C. elegans environmental RNAi/transcriptome biology is not a therapeutic oligonucleotide under study."", ""grounding_quote"": """", ""source_pmid"": ""36993640"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32459,curation_candidate,40272,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a review of RNAi therapeutics and technologies, not a primary observed off-target result."", ""grounding_quote"": """", ""source_pmid"": ""35680378"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32460,curation_candidate,40301,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports LNP siRNA delivery, cytotoxicity, and tumor efficacy, not an unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""36191773"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32461,curation_candidate,40302,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports spray-dried LNP formulation and pulmonary delivery feasibility, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""36126785"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32462,curation_candidate,40306,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports siRNA nanovaccine construction, uptake, cytokines, and efficacy, not unintended off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""36117149"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32463,curation_candidate,40308,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a review of antitumoral oligonucleotide therapeutics, not primary off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""35701833"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32464,curation_candidate,40309,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage discusses LNP delivery to liver cell populations, not an unintended off-target result."", ""grounding_quote"": """", ""source_pmid"": ""35642083"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.374948+00:00
32465,offtarget_evidence,539,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Observed scramble-siRNA effect indicates an unintended siRNA off-target response; generic cell-line support so Grade C."", ""grounding_quote"": ""We found that double knockdown of p42-MAPK and Rheb increased DTX-toxicity in LNCaP but not in PC3 cells. However, we also observed the same effect when scramble siRNA was used, therefore pointing to an off-target effect."", ""source_pmid"": ""36365241"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.377467+00:00
32466,curation_candidate,40326,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports siRNA-SNA stability, cytotoxicity, and on-target knockdown, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""35143189"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.377467+00:00
32467,curation_candidate,40377,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports targeted siRNA delivery, tumor inhibition, and absence of toxicity, not an unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""34042551"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.377467+00:00
32468,curation_candidate,40379,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports LNP delivery and tolerability in neurons, not observed off-target biology."", ""grounding_quote"": """", ""source_pmid"": ""34873640"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.377467+00:00
32469,curation_candidate,40382,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a delivery review for oligonucleotide therapeutics, not primary off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""33821570"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.377467+00:00
32470,curation_candidate,40387,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a renal oligonucleotide therapy review and mentions off-targets only as development concerns."", ""grounding_quote"": """", ""source_pmid"": ""33809425"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.377467+00:00
32471,curation_candidate,40389,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a review of oligonucleotide delivery approaches, not primary off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""34505766"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.377467+00:00
32472,curation_candidate,40404,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports exosome siRNA delivery, gene knockdown, and tumor regression, not an unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""33999716"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.377467+00:00
32473,curation_candidate,40411,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: off-target is assessed only computationally by genome matching; no observed off-target result is reported."", ""grounding_quote"": """", ""source_pmid"": ""34089909"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.377467+00:00
32474,curation_candidate,40413,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports in-silico siRNA specificity prediction and docking, not observed off-target biology."", ""grounding_quote"": """", ""source_pmid"": ""33786418"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32475,curation_candidate,40462,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports G-quadruplex oligonucleotide chemistry/delivery, toxicity, and target inhibition, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""33374392"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32476,curation_candidate,40470,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: passage concerns endogenous pathological sense/antisense RNA repeats, not a therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""31991801"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32477,curation_candidate,40472,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports siRNA scaffold chemistry, tissue distribution, and efficacy, not unintended off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""32672813"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32478,curation_candidate,40480,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports MYC ASO on-target antitumor efficacy and tumor regression, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""32805488"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32479,curation_candidate,40590,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports cholesterol-siRNA chemistry for extracellular-vesicle loading and Huntingtin silencing, not off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""29937418"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32480,curation_candidate,40591,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports MIS416-siRNA delivery and Stat3 knockdown, not unintended off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""29893623"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32481,curation_candidate,40593,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a review of lipid-conjugated siRNA delivery, not primary off-target evidence."", ""grounding_quote"": """", ""source_pmid"": ""29746209"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32482,curation_candidate,40639,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports oligonucleotide thrombocytopenia/toxicity mechanisms, not off-target evidence for the offtarget domain."", ""grounding_quote"": """", ""source_pmid"": ""29107969"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32483,curation_candidate,40709,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports CpG-ODN adjuvant synthesis, stability, and immunogenic potency, not unintended off-target effects."", ""grounding_quote"": """", ""source_pmid"": ""27074387"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32484,curation_candidate,40987,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports antisense exon-skipping rationale, not an observed unintended off-target effect."", ""grounding_quote"": """", ""source_pmid"": ""22869723"", ""candidate_domain"": ""offtarget""}",2026-06-07T21:51:24.378300+00:00
32485,curation_candidate,10862,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports siRNA off-target mitigation, not a toxicity or safety endpoint."", ""grounding_quote"": """", ""source_pmid"": ""33928567"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.378300+00:00
32486,curation_candidate,11043,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports PMO-AON nanobubble delivery failure, not a measured toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""32679000"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.378300+00:00
32487,curation_candidate,11114,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: LUAD methylation/transcriptome prognostic model; no therapeutic oligonucleotide is the agent under study."", ""grounding_quote"": """", ""source_pmid"": ""39053673"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.378300+00:00
32488,curation_candidate,11120,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: colon-cancer transcriptome review/overview contains no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""37059270"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.378300+00:00
32489,curation_candidate,11122,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: paraquat-induced pulmonary fibrosis toxicology is about an external toxin, not oligonucleotide safety."", ""grounding_quote"": """", ""source_pmid"": ""35817254"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.378300+00:00
32490,toxicity_endpoint,1388,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Intravitreal TTR siRNA conjugate safety is directly evaluated with an observed IOP spike; abstract support so Grade B."", ""grounding_quote"": ""This study aims to evaluate the efficacy and safety of intravitreal TTR siRNA conjugate injection into rabbit eyes. Rabbit (r) TTR siRNA is a screened TTR siRNA conjugate from 53 candidates. The intraocular pressure (IOP) immediately after injection was high despite the 65.9 % decrease of aqueous humor TTR protein levels in the rTTR siRNA group compared with those in the Control siRNA group 2 weeks after the 50 μL siRNA injection."", ""source_pmid"": ""38157582"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.380303+00:00
32491,toxicity_endpoint,1389,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""GalNAc-siRNA chronic dosing reports no adverse effects in rodents; generic abstract support so Grade C."", ""grounding_quote"": ""This enabled the SC administration of siRNA-GalNAc conjugates at therapeutically relevant doses and, importantly, at dose volumes of ≤1 mL. Chronic weekly dosing resulted in sustained dose-dependent gene silencing for over 9 months with no adverse effects in rodents."", ""source_pmid"": ""25434769"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.380303+00:00
32492,curation_candidate,14254,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: DNA damage and cell death are cancer-radiotherapy efficacy readouts; biocompatibility is too nonspecific for toxicity acceptance."", ""grounding_quote"": """", ""source_pmid"": ""40025923"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.380303+00:00
32493,curation_candidate,14323,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: siRNA is used as a research knockdown tool to study atorvastatin pharmacokinetics, not as the therapeutic under study."", ""grounding_quote"": """", ""source_pmid"": ""39909477"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.380303+00:00
32494,curation_candidate,14370,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a review of ATTR-CM therapies and trial landscape, not a primary toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39775625"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.380303+00:00
32495,curation_candidate,14435,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: siRNA transfection is only a validation tool for gallbladder-cancer marker biology, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""38716548"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.380303+00:00
32496,curation_candidate,15067,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a review/search summary of PCSK9 and Lp(a) silencing therapies, not a primary toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""37524569"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.380303+00:00
32497,curation_candidate,15134,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: shRNA knockdown is used as a validation tool for ellagic-acid cancer biology, not an oligonucleotide therapeutic."", ""grounding_quote"": """", ""source_pmid"": ""33862123"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.380303+00:00
32498,curation_candidate,15135,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: siRNA knockdown is a functional assay for lncRNAs in DVT biology, not a therapeutic oligonucleotide safety result."", ""grounding_quote"": """", ""source_pmid"": ""33580494"", ""candidate_domain"": ""toxicity""}",2026-06-07T21:51:24.380303+00:00
32499,toxicity_endpoint,1390,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Chemical-modification-induced siRNA structural distortion is linked to reduced off-target effect; generic abstract support so Grade C."", ""grounding_quote"": ""Here, we introduce small interfering RNA root-mean-square deviation (siRMSD), a novel parameter that quantifies structural distortions induced by chemical modifications in siRNAs. We demonstrate a strong correlation between deviations from the canonical A-form RNA structure and the reduction in siRNA off-target effect."", ""source_pmid"": ""40877521"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.380303+00:00
32500,curation_candidate,24,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports hepatotoxicity and seed-based off-target biology, not a chemistry modification-vs-property measurement."", ""grounding_quote"": """", ""source_pmid"": ""40134378"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.380303+00:00
32501,toxicity_endpoint,1391,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""PANAC chemistry creates GalNAc-siRNA conjugates with superior gene-silencing effect; generic support so Grade C."", ""grounding_quote"": ""Leveraging the advantages of PANAC photoclick chemistry and modular conjugation linkers, our method enables the direct assembly of trivalent GalNAc (tGalNAc) with commercially available primary-amine-modified siRNAs. This approach demonstrates the efficient and rapid assembly of therapeutically relevant oligonucleotides with ligands of interest, offering operational simplicity and practicality; thus, it effectively overcomes the limitations of existing methods. More importantly, the developed siRNA–tGalNAc conjugates showed a robust gene silencing effect superior to the parent siRNA conjugate"", ""source_pmid"": ""40151235"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32502,curation_candidate,136,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: excerpt is background on siRNA limitations and chemical modifications; no primary chemistry-vs-effect result is shown."", ""grounding_quote"": """", ""source_pmid"": ""41012491"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32503,curation_candidate,185,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage describes PK-PD modeling of GalNAc-siRNA disposition/pharmacology, not an observed chemistry modification-vs-property comparison."", ""grounding_quote"": """", ""source_pmid"": ""37871778"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32504,toxicity_endpoint,1392,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Designed 2-prime ribose modifications change siRNA stability, silencing activity, and off-target effects; generic support so Grade C."", ""grounding_quote"": ""following the substitution of the conventional 2′-O-methyl or 2′-O-fluoro ribose modifications with our newly designed functional groups, although the thermal stability of the duplexes decreased, the in vitro silencing activity against proprotein convertase subtilisin/kexin type 9 (PCSK9) gene was significantly enhanced and the off-target effects of specific genes could be effectively mitigated"", ""source_pmid"": ""41646886"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32505,toxicity_endpoint,1393,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Seed-region chemical modifications are shown to alter AGO2-bound structure and off-target binding; generic support so Grade C."", ""grounding_quote"": ""Here, we show that structural distortions caused by chemical modifications determine off-target effects. Modifications, including 2′-O-methoxyethyl, 2′-O-methyl, and 2′-formamido, at positions 2–5 disrupted the A-form RNA duplex on argonaute 2, preventing stable binding to target mRNA."", ""source_pmid"": ""41467115"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32506,toxicity_endpoint,1394,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""PS/LNA oligonucleotide modification status is linked to measured antiviral IC50 changes; generic support so Grade C."", ""grounding_quote"": ""Variations in the 50% inhibitory viral reproductive dose (IC50) values among the oligonucleotides were observed, depending upon both the target and the incorporated LNA modification. Optimal IC50 values (90 ± 10 nM) were achieved using a PS oligonucleotide lacking LNA modifications, which targeted the HIV-1 integrase-encoding genomic region. Optimal HIV inhibitory action among LNA constructs was observed in an oligonucleotide with a 5’-end LNA modification targeting the HIV integrase region (IC50 = 1.12 ± 0.03 μM). The introduction of LNA modifications to PS oligonucleotides failed to enhance antiviral activity"", ""source_pmid"": ""41704705"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32507,curation_candidate,489,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports aptamer-liposome delivery of apigenin and antitumor DNA damage, not oligo chemistry-vs-property evidence."", ""grounding_quote"": """", ""source_pmid"": ""36694259"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32508,toxicity_endpoint,1395,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Cycloalkane-bridged BNA/LNA chemistry maintains ASO activity with reduced PS modification; generic support so Grade C."", ""grounding_quote"": ""Both scpBNA- and scpBNA2-modified ASOs exhibited antisense activity comparable to that of their 2′,4′-BNA/LNA-modified counterparts, maintaining activity even with reduced PS modifications in the scpBNA- or scpBNA2-modified regions"", ""source_pmid"": ""41169576"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32509,toxicity_endpoint,1396,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Nucleobase modifications in gapmer ASOs are experimentally linked to reduced hepatotoxicity; generic support so Grade C."", ""grounding_quote"": ""In this study, we introduced single or multiple combinations of 17 nucleobase derivatives, including four novel derivatives, into hepatotoxic locked nucleic acid gapmer ASOs and examined their effects on hepatotoxicity. The results demonstrated successful identification of chemical modifications that strongly reduced the hepatotoxicity of gapmer ASOs."", ""source_pmid"": ""35801870"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32510,curation_candidate,652,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports toxicity mechanisms of LNA-containing ASOs rather than a specific chemistry modification changing a measured property."", ""grounding_quote"": """", ""source_pmid"": ""34060347"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32511,curation_candidate,687,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: erratum fragment reports omitted urinary-glucose table data only; no chemistry-vs-effect oligo result is judgeable."", ""grounding_quote"": """", ""source_pmid"": ""40083647"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32512,toxicity_endpoint,1397,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""GalNAc3 conjugation is linked to improved ASO potency and lower exposure; ISIS 702843 abstract support so Grade B."", ""grounding_quote"": ""A significant advancement in improving uptake into cells has come through the conjugation of ASOs to triantenarry N-acetyl-galactosamine (GalNAc3), a ligand for the asialoglycoprotein receptor on hepatocytes. The impact for antisense oligonucleotides, which are already taken up into hepatocytes, is a 10-fold improvement in potency in mice and up to a 30-fold potency improvement in humans, resulting in overall lower effective dose and exposure levels."", ""source_pmid"": ""33431610"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32513,curation_candidate,756,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports pharmacology/safety of an LNA gapmer, not a chemistry modification-vs-property comparison."", ""grounding_quote"": """", ""source_pmid"": ""35057094"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32514,toxicity_endpoint,1398,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Single alkyl phosphonate seed-region modification improves specificity and reduces off-target effects; generic support so Grade C."", ""grounding_quote"": ""siRNAs modified with a single alkyl phosphonate linkage demonstrated enhanced specificity and therapeutic profile compared to the parent siRNA. We found that these modifications are most effective when positioned at the internucleotide linkages 6–7 from the 5′-end of the guide strand. Our findings reveal that siRNAs with this modification maintain robust on-target activity both in vitro and in vivo. Importantly, differential gene expression (DGE) analysis showed a significant reduction in off-target effects across in vitro and in vivo, leading to an improved therapeutic profile."", ""source_pmid"": ""40737088"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32515,curation_candidate,882,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a review summary of ASO and peptide-conjugated ASO adverse reactions, not primary chemistry evidence."", ""grounding_quote"": """", ""source_pmid"": ""38983605"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32516,curation_candidate,1169,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage describes an LC-MS/MS bioanalysis method for antibody-siRNA conjugates, not chemistry-vs-effect evidence."", ""grounding_quote"": """", ""source_pmid"": ""40888416"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32517,curation_candidate,1248,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is review-style discussion of LNP immune responses, not primary chemistry-vs-effect evidence."", ""grounding_quote"": """", ""source_pmid"": ""39771501"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32518,curation_candidate,1490,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: passage reports preclinical toxicity/toxicokinetics of a phosphorothioate oligo, not a modification-vs-property comparison."", ""grounding_quote"": """", ""source_pmid"": ""20886212"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32519,curation_candidate,1771,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: passage is a review/expert-opinion discussion of chemical modifications and ADME, not primary observed chemistry evidence."", ""grounding_quote"": """", ""source_pmid"": ""23451977"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.381331+00:00
32520,toxicity_endpoint,1399,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""GNA isonucleotide chemistry improves GalNAc-siRNA activity and off-target profile; generic support so Grade C."", ""grounding_quote"": ""Transposition of the hydrogen-bond donor/acceptor pairs using the novel (S)-GNA-isocytidine and -isoguanosine nucleotides could rescue productive base-pairing with the complementary G or C ribonucleotides, respectively. GalNAc-siRNAs containing these GNA isonucleotides showed an improved in vitro activity, a similar improvement in off-target profile"", ""source_pmid"": ""34648028"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.382335+00:00
32521,curation_candidate,2086,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: aptamer is used for food-safety sensing, not as a therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""41289776"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.382335+00:00
32522,curation_candidate,2477,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review/background on GalNAc and NAT delivery; no primary chemistry-to-effect measurement in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""35919168"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.382335+00:00
32523,toxicity_endpoint,1400,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""3' terminal 2'-O-methyl modification changed siRNA silencing activity; generic abstract evidence so Grade C."", ""grounding_quote"": ""Here, we systematically evaluated the impact of 3′ terminal modifications (2′-O-methyl versus 2′-fluoro) on guide strands of different length and showed that 3′ terminal 2′-O-methyl modification negatively impacts activity for >60% of siRNA sequences tested but only in the context of 20- and not 19- or 21-nt-long guide strands."", ""source_pmid"": ""32610253"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.382335+00:00
32524,curation_candidate,2764,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: passage studies mRNA vaccine constructs, which are excluded rather than therapeutic oligonucleotides."", ""grounding_quote"": """", ""source_pmid"": ""40612710"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.382335+00:00
32525,curation_candidate,3017,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: transcriptome study of adipocytes; no therapeutic oligonucleotide agent is under study."", ""grounding_quote"": """", ""source_pmid"": ""31963662"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.383334+00:00
32526,toxicity_endpoint,1401,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""VHP modification of siRNA-loaded exosomes improved endothelial targeting and delivery; abstract support so Grade B."", ""grounding_quote"": ""VHP modification facilitated the targeted delivery of siRNA@VG-Exos to damaged endothelium, promoting their accumulation and subsequent release at the IRI site."", ""source_pmid"": ""41491215"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.383334+00:00
32527,curation_candidate,3455,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: morpholinos are discussed as zebrafish research knockdown tools in a review, not therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""41107628"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.383334+00:00
32528,toxicity_endpoint,1402,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""PDA/CD11b-modified nanoparticle carrying siRNA showed stimulus-triggered release and uptake; abstract support so Grade B."", ""grounding_quote"": ""Nanomaterials were also equipped with polydopamine (PDA) and CD11b to respond to reactive oxygen species/pH in the lesion environment and target neutrophils, respectively. As expected, Dio/siICAM-1@MSN@PDA-CD11b was successfully constructed to realize the rapid release of Dio and siICAM-1 under condition of pH6.4+H2O2. It also exhibited enhanced targeting properties with more intracellular uptake by neutrophils."", ""source_pmid"": ""40977834"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.383334+00:00
32529,toxicity_endpoint,1403,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Fluorocarbon/aptamer comodified DNA framework improved siRNA internalization, release and silencing; abstract support so Grade B."", ""grounding_quote"": ""Systematic optimization revealed that a surface modification ratio of 3:1 (fluorocarbon to aptamer) among the 90 available sites yielded synergistic improvements in internalization and cytosolic release, significantly enhancing siRNA-mediated gene silencing."", ""source_pmid"": ""40747059"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.384332+00:00
32530,curation_candidate,4163,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: excerpt reports efficacy/safety of a TTR siRNA conjugate injection, not a chemistry modification-vs-property comparison."", ""grounding_quote"": """", ""source_pmid"": ""38157582"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.384332+00:00
32531,toxicity_endpoint,1404,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Cholesterol-siRNA conjugate showed delivery and anti-inflammatory activity; abstract support so Grade B."", ""grounding_quote"": ""In this study, we characterize a simple cholesterol-short-interfering RNA (siRNA) conjugate system targeting Tnf mRNA in liver macrophages for the treatment of NAFLD. First, we observed delivery and anti-inflammatory activity in an acute liver inflammation model."", ""source_pmid"": ""36318487"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.384332+00:00
32532,toxicity_endpoint,1405,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Chemically modified siRNAs achieved allele-specific mutant huntingtin lowering; abstract support so Grade B."", ""grounding_quote"": ""Chemically modified siRNAs distinguish between mutant and normal huntingtin based on a single nucleotide difference and lower mutant huntingtin specifically in patient derived cells"", ""source_pmid"": ""36192390"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.385331+00:00
32533,toxicity_endpoint,1406,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Specific siRNA chemical optimization improved placental accumulation, silencing and safety; abstract support so Grade B."", ""grounding_quote"": ""Here, we systematically evaluate these parameters and demonstrate that increasing 2′-O-methyl modifications and 5′ chemical stabilization and using sequence-specific duplex asymmetry and a phosphocholine-docosanoic acid conjugate enhance placental accumulation, silencing efficiency and safety of sFLT1-targeting siRNAs."", ""source_pmid"": ""35847173"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.385331+00:00
32534,curation_candidate,4372,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: excerpt describes a delivery formulation/photochemical internalization system, not a chemistry modification-vs-property result."", ""grounding_quote"": """", ""source_pmid"": ""34437914"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.385331+00:00
32535,toxicity_endpoint,1407,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Pip6a-PMO conjugation enhanced ASO muscle delivery versus unconjugated PMO; abstract support so Grade B."", ""grounding_quote"": ""Pip6a-conjugated morpholino phosphorodiamidate oligomer (PMO) dramatically enhanced ASO delivery into striated muscles of DM1 mice following systemic administration in comparison with unconjugated PMO and other ASO strategies."", ""source_pmid"": ""31479430"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32536,curation_candidate,4540,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: LNA probes are used for Helicobacter pylori detection/FISH, not as therapeutic oligonucleotides."", ""grounding_quote"": """", ""source_pmid"": ""24278398"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32537,curation_candidate,5056,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: RYK siRNA is used to modify BMSCs in a cell-biology study, not as the therapeutic oligo under characterization."", ""grounding_quote"": """", ""source_pmid"": ""41963704"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32538,curation_candidate,5142,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: AAV2-encoded shRNA viral vector is excluded from therapeutic oligonucleotide scope."", ""grounding_quote"": """", ""source_pmid"": ""41913229"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32539,curation_candidate,5415,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: aptamer is used in a fumonisin biosensor, not as a therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""41744751"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32540,curation_candidate,6095,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: study is modified cell-penetrating peptide/protein delivery; siRNA is only a receptor knockdown tool."", ""grounding_quote"": """", ""source_pmid"": ""41471374"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32541,curation_candidate,6306,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: pemafibrate/lifestyle intervention trial has no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""41237431"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32542,curation_candidate,7476,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: aptamer is used for ochratoxin biosensing, not as a therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""40198995"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32543,curation_candidate,7963,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of bioconjugate delivery strategies; no primary chemistry result is reported in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39477529"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32544,curation_candidate,8459,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: heparan sulfate proteoglycan biology study has no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""38328107"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.386838+00:00
32545,toxicity_endpoint,1408,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""sgc8-conjugated siBCL11B nanoparticle selectively targeted cells and inhibited viability; abstract support so Grade B."", ""grounding_quote"": ""We demonstrate that sgc8-conjugated siBCL11B nanoparticles selectively and efficiently target BCL11B-overexpressing T-ALL cells, significantly inhibiting cell viability and promoting apoptosis"", ""source_pmid"": ""39583320"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.394845+00:00
32546,toxicity_endpoint,1409,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Fully chemically modified siRNAs showed greater tissue retention and productive silencing; abstract support so Grade B."", ""grounding_quote"": ""We show that fully modified siRNAs are retained at 100x greater levels in various tissues, independently of the nature of the conjugate or siRNA sequence, and support productive mRNA silencing."", ""source_pmid"": ""29432571"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.403740+00:00
32547,toxicity_endpoint,1410,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""5'-vinylphosphonate modification improved conjugated siRNA tissue accumulation and silencing duration; abstract support so Grade B."", ""grounding_quote"": ""Specifically, 5΄-vinylphosphonate (i) increases siRNA accumulation in tissues, (ii) extends duration of silencing in multiple organs and (iii) protects siRNAs from 5΄-to-3΄ exonucleases."", ""source_pmid"": ""28591791"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.410255+00:00
32548,curation_candidate,9583,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review/background on oligonucleotide chemistry; no observed primary result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""28244990"", ""candidate_domain"": ""chemistry""}",2026-06-07T21:51:24.410255+00:00
32549,toxicity_endpoint,1411,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""TfR antibody-ASO conjugates show brain delivery via transcytosis; weak abstract support so Grade C."", ""grounding_quote"": ""transferrin receptor (TfR)-targeting antibody–ASO conjugates have shown promise for brain delivery of ASOs via transcytosis in preclinical studies."", ""source_pmid"": ""41166443"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.410255+00:00
32550,curation_candidate,137,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: background/PBPK setup on siRNA properties; no measured delivery result is reported in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""41012491"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32551,curation_candidate,190,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: methods/design passage for CA9-targeted LNPs; no observed delivery or efficacy result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""42205867"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32552,toxicity_endpoint,1412,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Dynamic ASO polyplex enriched ASO in sentinel lymph nodes and improved delivery; abstract support so Grade C."", ""grounding_quote"": ""Here, we demonstrated a molecular approach to engineering a dynamic polyplex, predominantly comprising two poly(ethylene glycol)-(glycine-lysine)10 [PEG-(GK)10] per antisense oligonucleotide (ASO) based on charge neutralization at a minimum molecular ratio, that can enhance SLN functional delivery of ASOs for replenishing immunity against breast cancer recurrence and metastasis. Using a murine breast cancer model, we successfully enriched the ASO distribution in the SLN while limiting off-target organ distribution by tuning the size of the PEG (3-80 kDa)."", ""source_pmid"": ""40540297"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32553,curation_candidate,569,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: agricultural/insect dsRNA RNAi is explicitly outside scope."", ""grounding_quote"": """", ""source_pmid"": ""41970227"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32554,curation_candidate,585,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: narrative review of TNBC nanocarriers; no primary delivery result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""41899235"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32555,curation_candidate,779,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: CRISPR-Cas9 mRNA/sgRNA delivery is excluded from oligonucleotide therapeutic scope."", ""grounding_quote"": """", ""source_pmid"": ""34880218"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32556,curation_candidate,1127,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review/overview of pulmonary route; no primary siRNA delivery result is reported."", ""grounding_quote"": """", ""source_pmid"": ""41658564"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32557,curation_candidate,1143,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: antibody-oligonucleotide conjugates are spatial-proteomics detection reagents, not therapeutic delivery products."", ""grounding_quote"": """", ""source_pmid"": ""41311216"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32558,curation_candidate,1170,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: bioanalytical quantification method for antibody-siRNA conjugates, not an observed delivery-to-effect result."", ""grounding_quote"": """", ""source_pmid"": ""40888416"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32559,toxicity_endpoint,1413,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""PNMVA lipid carrier preserved siRNA lipoplex uptake and endosomal escape; abstract support so Grade C."", ""grounding_quote"": ""This work highlights the great potential of amphiphilic poly(N-methyl-N-vinylacetamide) (PNMVA) derivatives as alternatives to lipid-PEG for siRNA delivery. PNMVA compounds with different degrees of polymerization and hydrophobic segments, are synthesized. Among them, DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine)-PNMVA efficiently integrates into lipoplexes and LNP membranes and prevents protein corona formation around these lipid carriers, exhibiting stealth properties comparable to DSPE-PEG. However, unlike DSPE-PEG, DSPE-PNMVA24 shows no adverse impact on lipoplexes cell uptake and endosomal escape."", ""source_pmid"": ""37994483"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32560,curation_candidate,1332,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: mRNA delivery system is excluded from therapeutic oligonucleotide scope."", ""grounding_quote"": """", ""source_pmid"": ""38079547"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32561,curation_candidate,1673,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: carrier evaluates mRNA/pDNA delivery, not an in-scope therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""38984864"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.411256+00:00
32562,toxicity_endpoint,1414,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Nucleic-acid aptamer conjugate improved tumor accumulation and targeted delivery; abstract support so Grade C."", ""grounding_quote"": ""Cisplatin-arabinogalactan-aptamer (Cis-AG-Ap) conjugate was synthesized based on Cis-dichlorodiammineplatinum, Siberian larch arabinogalactan, and aptamer AS-42 specific to heat-shock proteins (HSP) 71 kDa (Hspa8) and HSP 90-beta (Hsp90ab1). The antitumor effect was estimated using ascites and metastatic Ehrlich tumor models. Cis-AG-Ap toxicity was assessed by blood biochemistry on healthy mice. Here, we demonstrated enhanced anticancer activity of Cis-AG-Ap and its specific accumulation in tumor foci. It was shown that targeted delivery allowed a 15-fold reduction in the therapeutic dose of cisplatin and its toxicity."", ""source_pmid"": ""35921069"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.412255+00:00
32563,toxicity_endpoint,1415,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Hydrogel/PLGA platform delivered therapeutic FGFR2 siRNA with cytoplasmic delivery; abstract support so Grade C."", ""grounding_quote"": ""PLGA NPs demonstrated high siRNA encapsulation efficiency, efficient cytoplasmic delivery"", ""source_pmid"": ""41647289"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.413265+00:00
32564,curation_candidate,3234,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of CNS oligonucleotide bioconjugates; no primary delivery result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""41547494"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.413265+00:00
32565,toxicity_endpoint,1416,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""scFv-modified macrophage-membrane liposomes improved LPCAT1 siRNA uptake and silencing; abstract support so Grade C."", ""grounding_quote"": ""In vitro, scFv-MML@LPCAT1si exhibited superior cellular uptake and silencing of LPCAT1 expression in EGFR-positive PC9 cells"", ""source_pmid"": ""40898177"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.413265+00:00
32566,curation_candidate,4043,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review on LNP delivery beyond the liver; no observed delivery result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39139067"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.413265+00:00
32567,toxicity_endpoint,1417,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Hydrophobically modified peptide delivered siRNA to lung; abstract support so Grade C."", ""grounding_quote"": ""The leading candidate peptide selected from a library containing 12 amino acids showed strong lung‐targeted siRNA delivery capacity after hydrophobic modification."", ""source_pmid"": ""38311577"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.416260+00:00
32568,curation_candidate,4338,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: scaffold/tether design passage lacks a measured therapeutic oligo delivery effect."", ""grounding_quote"": """", ""source_pmid"": ""35049734"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.416260+00:00
32569,toxicity_endpoint,1418,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""PAMAM-morpholino nanoconjugates enhanced cellular oligonucleotide delivery; abstract support so Grade C."", ""grounding_quote"": ""Conjugation of neutral morpholino oligonucleotides (ONs) with PAMAM dendrimers resulted in neutral, uniform, and ultra-small (~10nm) nanoconjugates. The nanoconjugates dramatically enhanced cellular delivery of the ONs in cancer cells."", ""source_pmid"": ""26134311"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.419781+00:00
32570,curation_candidate,4655,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: NorCA is a bile-acid small molecule; no therapeutic oligonucleotide agent is present."", ""grounding_quote"": """", ""source_pmid"": ""42196402"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.419781+00:00
32571,curation_candidate,4785,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: kaempferol is a small molecule and siRNA knockdown is only a mechanistic tool."", ""grounding_quote"": """", ""source_pmid"": ""42123354"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.419781+00:00
32572,toxicity_endpoint,1419,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""PLA-RGD-KA26 siRNA nanocomplexes enhanced uptake and NSUN2 knockdown; abstract support so Grade C."", ""grounding_quote"": ""The resulting PLA-RGD-KA26-siRNA nanocomplexes (PRR) exhibited uniform nanoscale dimensions, a positive surface charge, and high colloidal stability in aqueous solution. In vitro studies demonstrated significantly enhanced cellular uptake and efficient NSUN2 knockdown across multiple CRC cell lines"", ""source_pmid"": ""42093739"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.422781+00:00
32573,curation_candidate,5495,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: excerpt supports RNA/mRNA vaccine delivery platform, not an in-scope therapeutic oligo result."", ""grounding_quote"": """", ""source_pmid"": ""41691403"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.422781+00:00
32574,toxicity_endpoint,1420,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""SANGs accumulated in tumors and delivered RNAi payloads suppressing oncogenes; abstract support so Grade C."", ""grounding_quote"": ""After intravenous injection, SANGs preferentially accumulate and are retained in primary and metastatic loci in four aggressive cancer models in rodents. SANGs deliver multiple RNAi payloads that significantly suppress oncogene expression and sensitize previously resistant tumors while being safe and well tolerated in simulated clinical applications across three species."", ""source_pmid"": ""41500988"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.426285+00:00
32575,curation_candidate,6246,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of chemical brain-delivery strategies; no primary result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""41291238"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.426285+00:00
32576,curation_candidate,6288,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: AG-PNA conjugates show antibacterial activity, but no delivery or uptake effect is reported."", ""grounding_quote"": """", ""source_pmid"": ""41259288"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.426285+00:00
32577,curation_candidate,6628,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: synthetic circRNA vaccine delivery is outside therapeutic oligonucleotide scope."", ""grounding_quote"": """", ""source_pmid"": ""40930161"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.426285+00:00
32578,curation_candidate,6630,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: salvianolic acid F/ultrasound study is small-molecule delivery with no therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""40928959"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.426285+00:00
32579,toxicity_endpoint,1421,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""recNANPs conditionally released RNAi inducers and prolonged gene silencing; abstract support so Grade C."", ""grounding_quote"": ""The reconfigurable nucleic acid nanoparticles, or recNANPs, recognize overexpressed cancer biomarkers and conditionally release RNAi inducers targeting apoptosis inhibitors in pancreatic cancer cells. RecNANPs are non-immunostimulatory, achieve prolonged gene silencing compared to conventional RNAi inducers"", ""source_pmid"": ""40852577"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.431291+00:00
32580,curation_candidate,6961,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: passage is formulation/method setup for LNP/siMETTL16 plus mRNA vaccine, with no observed delivery result."", ""grounding_quote"": """", ""source_pmid"": ""40665962"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.431291+00:00
32581,toxicity_endpoint,1422,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""DNA nanohydrogel released ASOs after cellular uptake and enhanced cancer-cell inhibition; abstract support so Grade C."", ""grounding_quote"": ""Upon cellular uptake by cancer cells, the nanocarrier disassembled in the acidic tumor microenvironment, releasing DOX for chemotherapy and ASOs via toehold-mediated strand displacement (TMSD) for targeted gene silencing. Cellular studies demonstrated significantly enhanced cancer cell inhibition compared to single-agent treatments, highlighting strong combined effects."", ""source_pmid"": ""40305283"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.435289+00:00
32582,toxicity_endpoint,1423,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""HA-conjugated nanocarrier delivered GLUT1 siRNA to tumor sites and improved uptake; abstract support so Grade C."", ""grounding_quote"": ""In this study, we developed a biocompatible co-delivery system that incorporates hydroxycamptothecin (HCPT) and glucose transporter 1 (GLUT1) small interfering RNA (siRNA). HCPT was loaded onto gold nanoparticles through crystallization, ensuring drug stability and safety. The branched configuration of self-branched chitosan contributed to improved gene delivery efficiency. The hyaluronic acid-conjugated nanocarrier specifically targeted CD44 receptors expressed on AML cells, while the pH-sensitive properties of self-branched chitosan promoted localized drug and gene release. This system effectively delivered the therapeutic agents to tumor sites, improving cellular uptake"", ""source_pmid"": ""40147647"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.438798+00:00
32583,curation_candidate,7538,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: APS/HCC case report has no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""40128996"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.438798+00:00
32584,toxicity_endpoint,1424,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""CManDA/DNCA/CLD lipid system delivered siG12S with tumor targeting and silencing; abstract support so Grade C."", ""grounding_quote"": ""Here, we designed and synthesized a Gemini-type mannosylated peptidyl lipid called CManDA(M), which, in combination with the cytidinyl lipid DNCA(D) and the peptidyl lipid CLD(C) (D/50C/50M), could transfect siRNA (siG12S) into A549 cells to target and silence the KRASG12S gene. The fluorescence intensity in the tumor area of the D/50C/50M/Cy5.5-siG12S group increased by approximately 2.5 times. Furthermore, full 2'-F/2'-OMe-modified siG12Ss could also be transfected by D/50C/50M into cells, resulting in target gene silencing. The tumor weight in the D/50C/50M/M3 group (1.5 mg/kg, i.v.) was reduced by 50 % after administration in a mouse axillary tumor (A549) model, whereas the tumor bioluminescence intensity was only approximately 30 % of that in the blank group in a mouse orthotopic lung cancer model and showed no significant toxicity."", ""source_pmid"": ""40073943"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.442306+00:00
32585,curation_candidate,7786,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: generic smart drug delivery/imaging overview has no therapeutic oligonucleotide primary result."", ""grounding_quote"": """", ""source_pmid"": ""39757607"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.442306+00:00
32586,curation_candidate,7895,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: editorial/review on mRNA therapeutics and gene delivery; no primary result."", ""grounding_quote"": """", ""source_pmid"": ""39771568"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.442306+00:00
32587,curation_candidate,8095,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: CRISPR/Cas9 plasmid delivery is excluded even though an aptamer is used for targeting."", ""grounding_quote"": """", ""source_pmid"": ""39127174"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.442306+00:00
32588,curation_candidate,8186,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: lornoxicam nanoparticle formulation is small-molecule delivery, not oligonucleotide delivery."", ""grounding_quote"": """", ""source_pmid"": ""38953843"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.442306+00:00
32589,curation_candidate,8357,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: AAV9 vector-delivered shRNA is excluded from therapeutic oligonucleotide scope."", ""grounding_quote"": """", ""source_pmid"": ""38509093"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.442306+00:00
32590,toxicity_endpoint,1425,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Lysine-modified chitosan bound siRNA and showed uptake/transfection efficiency; abstract support so Grade C."", ""grounding_quote"": ""The results showed that LGCS could effectively bind to siRNA and form a complex with a hydrated diameter of about 97.2 ± 1.3 nm. Furthermore, cytotoxicity assays conducted on RSC96 cells demonstrated that LGCS exhibited lower toxicity compared to linear polyethyleneimine (PEI) 25k. In vitro, cellular uptake assays also revealed that LGCS displayed excellent transfection efficiency."", ""source_pmid"": ""39348656"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.447501+00:00
32591,curation_candidate,9156,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: intro/background on dendrimer siRNA carriers; no observed delivery result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""41304812"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.448500+00:00
32592,curation_candidate,9349,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: background/methods for nanoparticle siRNA delivery; no observed result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39099788"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.448500+00:00
32593,toxicity_endpoint,1426,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""3D tissue-slice testing observed siRNA nanoparticle transfection efficacy differences; abstract support so Grade C."", ""grounding_quote"": ""When used for the analysis of nanoparticles based on chemically modified polyethylenimines (PEIs) to deliver siRNA or DNA, differences in transfection efficacy and cytotoxicity between nanoparticles were observed more clearly than in 2D cell culture."", ""source_pmid"": ""36541426"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.456502+00:00
32594,toxicity_endpoint,1427,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""ZNF416 siRNA liposomes passively targeted fibrotic lung after tail-vein delivery; abstract support so Grade C."", ""grounding_quote"": ""Besides, ZNF416 siRNA-loaded liposome delivery by tail-vein could passively target the fibrotic area in the lung"", ""source_pmid"": ""36371191"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.465490+00:00
32595,toxicity_endpoint,1428,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""pH-responsive polymer-prodrug NPs accumulated in tumors and released siRNA-prodrug complexes; abstract support so Grade C."", ""grounding_quote"": ""After intravenous administration, the long-circulating NPs accumulate in tumor tissues and then rapidly release the siRNA-prodrug complexes via TME pH-mediated NP disassociation for subsequent tissue penetration and cytosolic transport."", ""source_pmid"": ""31381852"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.470517+00:00
32596,curation_candidate,9516,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review/discussion article on RNAi cancer delivery; no primary delivery measurement."", ""grounding_quote"": """", ""source_pmid"": ""30562145"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.471521+00:00
32597,toxicity_endpoint,1429,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Cysteamine gold nanoparticles delivered siRNA with target silencing; abstract support so Grade C."", ""grounding_quote"": ""We also observed that about 70 % transient silencing of the target gene was achieved with only 25 nM siRNA delivered by our nano-vehicle."", ""source_pmid"": ""39521158"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.476520+00:00
32598,toxicity_endpoint,1430,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Magnetic hyperthermia enabled siRNA transfection with lower toxicity; abstract support so Grade C."", ""grounding_quote"": ""Finally, we demonstrate the utility of this approach for the transfection of cells with a small interference RNA (siRNA), revealing a similar efficacy to a standard transfection method based on the use of cationic lipid-based reagents (such as Lipofectamine), but with lower cell toxicity."", ""source_pmid"": ""39052238"", ""candidate_domain"": ""delivery""}",2026-06-07T21:51:24.482725+00:00
32599,curation_candidate,1812,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""28448194"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.224770+00:00
32600,curation_candidate,2628,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""20128628"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.228374+00:00
32601,curation_candidate,3039,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""20410931"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.228374+00:00
32602,curation_candidate,4518,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""26051465"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.228374+00:00
32603,toxicity_endpoint,1431,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""Unmodified siRNA induced hepatic innate immune cytokines, while chemically modified siRNA did not; abstract-only generic siRNAs so Grade C."", ""grounding_quote"": ""Unmodified GAL siRNA transiently induced the expression of TNF-α, IL-6, IL-10, IFN-β and IFN-sensitive gene 15 in vivo, whereas a formulation of 2'-O-methylated-LUC siRNA had no such effects."", ""source_pmid"": ""24065781"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32604,curation_candidate,4545,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""23770039"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32605,curation_candidate,4573,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39999249"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32606,curation_candidate,9505,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""31072142"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32607,curation_candidate,9513,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""30720262"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32608,curation_candidate,9515,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""30637934"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32609,curation_candidate,9533,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""30091604"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32610,curation_candidate,9551,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""29584585"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32611,curation_candidate,9559,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""29250901"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32612,curation_candidate,9574,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""28655658"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32613,curation_candidate,9576,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""28605133"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32614,curation_candidate,9580,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""28373101"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32615,curation_candidate,9598,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""27890901"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32616,curation_candidate,9600,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""27711272"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32617,curation_candidate,9603,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""27629437"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32618,curation_candidate,9607,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""27588674"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32619,curation_candidate,10308,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""37589246"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32620,curation_candidate,10310,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38334488"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32621,curation_candidate,10362,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""39168524"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32622,curation_candidate,10437,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""39589322"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32623,curation_candidate,10450,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""36195820"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32624,curation_candidate,10537,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""32741234"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32625,curation_candidate,10540,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""32246854"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32626,curation_candidate,10558,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39670497"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32627,curation_candidate,10572,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38369231"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32628,curation_candidate,10573,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""37429729"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32629,curation_candidate,10599,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""33542028"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32630,curation_candidate,10601,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""33026966"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.230374+00:00
32631,curation_candidate,10603,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""32865780"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32632,curation_candidate,10604,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""32731935"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32633,curation_candidate,10611,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""31738395"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32634,curation_candidate,10743,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""39516029"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32635,curation_candidate,10749,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39110607"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32636,curation_candidate,10751,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38957973"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32637,toxicity_endpoint,1432,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""Fc-siRNA LNP formulation reports an observed in vivo safety profile, but endpoint detail is generic so Grade C."", ""grounding_quote"": ""Moreover, Fc-siRNA@O-LNPs encapsulated with ferrocene (Fc) and SLC7A11/Nrf2-targeted siRNA is formulated. The outcomes demonstrate optimal safety profiles and a significant anti-tumor effect by inducing long-lasting and efficient ferroptosis through a synergistic action in vivo."", ""source_pmid"": ""38829038"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32638,curation_candidate,10759,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38692053"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32639,curation_candidate,10765,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""38466819"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32640,curation_candidate,10769,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38291016"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32641,curation_candidate,10771,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38282246"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32642,curation_candidate,10773,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""38218350"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32643,curation_candidate,10778,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""37919256"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32644,curation_candidate,10779,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""37897397"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32645,curation_candidate,10782,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""37566146"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32646,curation_candidate,10785,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""37208184"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32647,curation_candidate,10786,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""37201764"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32648,curation_candidate,10802,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""36002054"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32649,toxicity_endpoint,1433,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""Oligonucleotide nanocomposites were administered in mice and reported as nontoxic under the tested conditions; generic ODN/ODNm support so Grade C."", ""grounding_quote"": ""new delivery system consisting of biocompatible low-toxic titanium dioxide nanoparticles and immobilized polylysine-containing oligonucleotides with the native (ODN) and partially modified (ODNm) internucleotide bonds. Intraperitoneal injection of the TiO2•PL-ODN nanocomposite provided 65-70% survival of mice, while intraperitoneal or oral administration of TiO2•PL-ODNm was somewhat more efficient (~80% survival). The virus titer in the lung was reduced by two-three orders of magnitude. The nanocomposites are nontoxic to mice under the used conditions."", ""source_pmid"": ""33753212"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32650,toxicity_endpoint,1434,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""Systemically administered circular siRNA showed in vivo activity without adverse effects; generic platform support so Grade C."", ""grounding_quote"": ""after systemic administration to mice, circular siRNA showed prolonged circulation and improved knockdown activity in the liver, kidney, and muscle, without causing adverse effects."", ""source_pmid"": ""33016851"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32651,curation_candidate,10829,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""32659676"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32652,toxicity_endpoint,1435,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""Named LNA-siRNA-2 had an observed improved safety/reduced side-effect result in xenograft models; abstract-only support so Grade B."", ""grounding_quote"": ""a selective siRNA, siRNA-2, which targets Aurora-A mRNA exon 2, was designed to translationally inhibit the expression of Aurora-A in cancer cells but not normal cells; locked nucleic acid (LNA)-modified siRNA-2 showed improved efficacy in inhibiting Aurora-A mRNA translation and tumor growth. Xenograft animal models combined with noninvasion in vivo imaging system (IVIS) analysis further confirmed the anticancer effect of LNA-siRNA-2 with improved efficiency and safety and reduced side effects."", ""source_pmid"": ""31875524"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32653,curation_candidate,10864,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""31429628"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32654,curation_candidate,10882,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""31144994"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32655,curation_candidate,10884,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""27500733"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32656,curation_candidate,10908,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""31270142"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32657,curation_candidate,10929,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""22454061"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32658,curation_candidate,10981,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""39181215"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32659,curation_candidate,10982,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39083128"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32660,curation_candidate,10984,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39053830"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32661,curation_candidate,10986,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38987439"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32662,curation_candidate,10989,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38909634"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32663,curation_candidate,10996,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38492614"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32664,curation_candidate,11002,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38060340"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32665,curation_candidate,11005,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""37970635"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32666,toxicity_endpoint,1436,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""RNA-loaded LNP formulation retained activity and lacked cytotoxic effects in a safety-sense cell assay; generic delivery platform so Grade C."", ""grounding_quote"": ""Spray-dried LNPs maintained bioactivity resulting in > 95 % protein downregulation and confirming the lack of cytotoxic effects in a lung adenocarcinoma cell line. Furthermore, the spray-dried and subsequently dried LNPs stored for 3 months at 4 °C and 25 °C achieved up to 50 % gene silencing of the house-keeping gene GAPDH after deposition on the mucus layer of Calu-3 cells. This study confirms the stability of spray-dried and subsequently dried LNPs over at least 90 days at 4 °C and 25 °C emphasizing the potential of dry powder inhalation of RNA-loaded LNPs as a therapy option for pulmonary diseases."", ""source_pmid"": ""37956785"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.231373+00:00
32667,toxicity_endpoint,1437,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""Phase I TRK-250 study reports observed adverse-event findings after inhaled dosing; named clinical oligo and abstract-only support so Grade B."", ""grounding_quote"": ""Purpose: TRK-250 is a novel single-stranded oligonucleotide carrying a human Transforming growth factor-beta 1-targeting siRNA motif tethered by two proline linkers. Nonclinical studies have shown that TRK-250 may have potency to prevent the progression of pulmonary fibrosis. Herein, a phase I study was conducted to investigate the safety and pharmacokinetics (PKs) of TRK-250 in patients with idiopathic pulmonary fibrosis (IPF). Method: In the phase I study, 34 IPF patients were partially randomized to receive a placebo or TRK-250 in 4 single doses of 2, 10, 30, and 60 mg or multiple rising doses of 10, 30, and 60 mg once per week for 4 weeks by oral inhalation. For both the single- and multiple-dose studies, the primary endpoint was safety, and the secondary endpoint was PKs. Result: In all IPF patients who orally inhaled TRK-250, no significant drug-related adverse events (AEs) were observed. The AEs were mild or moderate, except for one severe case with acute exacerbation. One of the more common AEs was coughing. One patient discontinued treatment before the last dose because of coughing."", ""source_pmid"": ""37738329"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32668,curation_candidate,11013,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""37408387"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32669,curation_candidate,11019,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""36804094"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32670,curation_candidate,11020,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""36610224"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32671,curation_candidate,11022,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""36587552"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32672,toxicity_endpoint,1438,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""ISIS 353512 ASO caused IL-6 and CRP increases and PBMC immune activation linked to TLR signaling; abstract-only named ASO so Grade B."", ""grounding_quote"": ""A human peripheral blood mononuclear cell (PBMC)-based assay was developed to identify antisense oligonucleotide (ASO) with the potential to activate a cellular innate immune response outside of an acceptable level. The development of this assay was initiated when ISIS 353512 targeting the messenger ribonucleic acid for human C-reactive protein (CRP) was tested in a phase I clinical trial, in which healthy human volunteers unexpectedly experienced increases in interleukin-6 (IL-6) and CRP. This level of immune stimulation was not anticipated following rodent and nonhuman primate safety studies in which no evidence of exaggerated proinflammatory effects were observed. The IL-6 increase induced by ISIS 353512 was caused by activation of B cells. The IL-6 induction was inhibited by chloroquine pretreatment of PBMCs and the nature of ASOs suggested that the response is mediated by a Toll-like receptor (TLR), in all likelihood TLR9."", ""source_pmid"": ""35976085"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32673,curation_candidate,11051,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""31184975"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32674,toxicity_endpoint,1439,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""Clinical NS-065/NCNP-01 morpholino ASO dosing reports no severe adverse drug reactions or discontinuations; abstract-only support so Grade B."", ""grounding_quote"": ""We conducted a phase 1, open-label, dose-escalation clinical trial to determine the safety, pharmacokinetics, and activity of NS-065/NCNP-01, a morpholino ASO that enables skipping of exon 53. Ten patients with DMD (6 to 16 years old), carrying mutations in the dystrophin gene whose reading frame would be restored by exon 53 skipping, were administered NS-065/NCNP-01 at doses of 1.25, 5, or 20 mg/kg weekly for 12 weeks. The primary endpoint was safety; the secondary endpoints were pharmacokinetics and successful exon skipping. No severe adverse drug reactions were observed, and no treatment discontinuation occurred."", ""source_pmid"": ""29669851"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32675,curation_candidate,11062,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""28799578"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32676,toxicity_endpoint,1440,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""IONIS-TTRRx ASO was administered in healthy volunteers and reported well tolerated without remarkable safety issues; abstract-only support so Grade B."", ""grounding_quote"": ""IONIS-TTRRx (ISIS 420915) is a 2nd-Generation 2'-O-(2-methoxyethyl) modified \""2'-MOE\"" antisense oligonucleotide (ASO) that targets the TTR RNA transcript and reduces the levels of the TTR transcript through an RNaseH1 mechanism of action, leading to reductions in both mutant and wild-type TTR protein. The activity of IONIS-TTRRx to decrease TTR protein levels was studied in transgenic mice bearing the Ile84Ser human TTR mutant, in cynomolgus monkeys and in healthy human volunteers. Robust (>80%) reductions of plasma TTR protein were obtained in all three species treated with IONIS-TTRRx, which in mice and monkeys was associated with substantial reductions in hepatic TTR RNA levels. These effects were dose-dependent and lasted for weeks post-dosing. In a Phase 1 healthy volunteer study, treatment with IONIS-TTRRx for four weeks was well tolerated without any remarkable safety issues."", ""source_pmid"": ""27355239"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32677,toxicity_endpoint,1441,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""Chronic drisapersen AON administration produced renal tubular degeneration and glomerulopathy; abstract-only named AON so Grade B."", ""grounding_quote"": ""Chronic administration of drisapersen, a 2'-OMe phosphorothioate antisense oligonucleotide (AON) to mice and monkeys resulted in renal tubular accumulation, with secondary tubular degeneration. Glomerulopathy occurred in both species with species-specific characteristics."", ""source_pmid"": ""24292388"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.232879+00:00
32678,toxicity_endpoint,1442,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""A biologically active antisense molecule induced sequence-specific genomic mutation in cells; unnamed/generic ASO support so Grade C."", ""grounding_quote"": ""Treating human lymphoblastoid cells with a biologically active antisense molecule induced sequence-specific mutation within genomic DNA over fourfold"", ""source_pmid"": ""22872057"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.233886+00:00
32679,curation_candidate,11082,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""22605630"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.233886+00:00
32680,curation_candidate,11084,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""22155317"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.233886+00:00
32681,curation_candidate,11135,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""26393365"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.233886+00:00
32682,curation_candidate,11478,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39547406"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.233886+00:00
32683,curation_candidate,11479,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39494631"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.233886+00:00
32684,curation_candidate,11485,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39352667"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.233886+00:00
32685,toxicity_endpoint,1443,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""STP705 HKP-siRNA nanoparticle showed localized activity without adverse systemic effects in preclinical models; abstract-only support so Grade B."", ""grounding_quote"": ""RESULTS: STP705 effectively reduced the expression of TGF-β1 and COX-2, with a notable decrease in adipocyte volume and lipid content without adverse systemic effects. In DIO mice, the HKP-siRNA complex demonstrated precise localization to injected adipose tissue, maintaining significant gene silencing, and detectable levels of siRNA for up to 14 days post-administration."", ""source_pmid"": ""39166716"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32686,curation_candidate,11510,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""38973236"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32687,curation_candidate,11516,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38804517"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32688,toxicity_endpoint,1444,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""Aptamer-siRNA chimera nanoparticle therapy reports reduced adverse reactions in animal experiments, but support is generic and combo-product confounded so Grade C."", ""grounding_quote"": ""Here, we constructed an AS1411 aptamer-programmed cell death ligand-1 (PD-L1) siRNA chimera/polyethylenimine/glutamine/β-cyclodextrin/doxorubicin (Chimera/ PEI/Gln/β-CD/DOX) nanoparticle for the combination therapy (chemotherapy combined with immunotherapy). Scanning electron microscopy showed that PEI/Gln/β-CD/DOX nanoparticle was conical, with a diameter of about 250-500 nm. AS1411 aptamer-PD-L1 siRNA chimera can effectively bind NSCLC cells and inhibit PD-L1 expression, further activating T cells and CD8+T cells. Glutamine modification effectively promoted the doxorubicin uptake by cancer cells and induced their apoptosis. Animal experiments showed that our nanoparticles effectively treated the transplanted tumor, and the adverse reactions were reduced."", ""source_pmid"": ""38554525"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32689,curation_candidate,11535,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38522817"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32690,curation_candidate,11544,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38380639"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32691,curation_candidate,11567,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""37827056"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32692,curation_candidate,11569,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""37653229"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32693,toxicity_endpoint,1445,human_curator_expand,apply_script.py,curator_verified,accept,zy,"{""reason"": ""RNAi therapeutics VIR-2218 and ALN-HBV are directly compared for ALT elevations in mice and healthy volunteers; abstract-only named therapeutics so Grade B."", ""grounding_quote"": ""ALN-HBV and VIR-2218 are investigational RNA interference therapeutics that target all major HBV transcripts. METHODS: We report on: i) the safety of single doses of VIR-2218 (modified from ALN-HBV by enhanced stabilization chemistry plus technology to reduce off-target, seed-mediated binding while maintaining on-target antiviral activity) and ALN-HBV in humanized mice; ii) a cross-study comparison of the safety of single doses of VIR-2218 and ALN-HBV in healthy human volunteers (n = 24 and n = 49, respectively); and iii) the antiviral activity of two doses of 20, 50, 100, 200 mg of VIR-2218 (total n = 24) vs. placebo (n = 8), given 4 weeks apart, in participants with cHBV infection. RESULTS: In humanized mice, alanine aminotransferase (ALT) levels were markedly lower following administration of VIR-2218 compared with ALN-HBV. In healthy volunteers, post-treatment ALT elevations occurred in 28% of participants receiving ALN-HBV compared with none in those receiving VIR-2218."", ""source_pmid"": ""37290591"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32694,curation_candidate,11580,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""37221913"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32695,curation_candidate,11581,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 1 fail: passage does not study an in-scope therapeutic oligo/delivery product; excluded/non-therapeutic modality or tool use."", ""grounding_quote"": """", ""source_pmid"": ""37195783"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32696,curation_candidate,11582,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 3 fail: passage reports delivery, PK/PD, biodistribution, efficacy, analytics, or tool activity rather than an oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""37164838"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.235400+00:00
32697,curation_candidate,11584,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""37070852"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32698,curation_candidate,11592,human_curator_expand,apply_script.py,curator_rejected,reject,zy,"{""reason"": ""GATE 2 fail: passage is review/background/method/design text or lacks an observed primary toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""36721963"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32699,curation_candidate,11598,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: passage is a review of mRNA-LNP shelf-life/stability and safety concerns; no therapeutic oligo toxicity result is reported."", ""grounding_quote"": """", ""source_pmid"": ""36588456"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32700,curation_candidate,11599,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/3 fail: reported immune/retinal events are for AAV2-REP1 gene therapy, while ASOs are only designed/tested as alternate therapy with no toxicity endpoint in excerpt."", ""grounding_quote"": """", ""source_pmid"": ""36581191"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32701,curation_candidate,11604,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review article summarizing inclisiran pharmacology/safety; not a primary observed toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""35775133"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32702,curation_candidate,11613,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: meeting report/ADME workshop summary with no administered oligonucleotide toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""36093882"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32703,curation_candidate,11658,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: oligonucleotide is used as a formulation component for insulin nanoparticles, not a therapeutic oligo/delivery product carrying an oligo under safety study."", ""grounding_quote"": """", ""source_pmid"": ""33769519"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32704,curation_candidate,11705,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: adverse effects are background rationale for CpG ODN design; IL-6 induction is intended immunostimulatory activity, not a safety endpoint."", ""grounding_quote"": """", ""source_pmid"": ""30835633"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32705,toxicity_endpoint,1446,human_curator_expand,apply_script.py,curator_verified,accept,ql,"{""reason"": ""IONIS-GCGRRx is an antisense oligo administered in phase 2 studies and dose-dependent liver transaminase increases were observed."", ""grounding_quote"": ""Dose-dependent increases in transaminases were observed with IONIS-GCGRRx, which were attenuated at lower doses and remained mostly within the normal reference range at the 50-mg dose."", ""source_pmid"": ""30765435"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32706,curation_candidate,11713,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: excerpt reports metabolic efficacy biomarkers for IONIS-PTP-1BRx but no observed safety/toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""29439147"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32707,toxicity_endpoint,1447,human_curator_expand,apply_script.py,curator_verified,accept,ql,"{""reason"": ""Apatorsen-treated patients had infusion reactions reported as the most common adverse event."", ""grounding_quote"": ""Infusion reactions were the most commonly reported adverse event occurring in 77% of apatorsen-treated patients."", ""source_pmid"": ""29250742"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32708,curation_candidate,11715,human_curator_expand,apply_script.py,curator_abstained,abstain,ql,"{""reason"": ""bad passage: excerpt truncates the toxicity sentence at 'No adverse events were re', so a complete grounding quote cannot be provided."", ""grounding_quote"": """", ""source_pmid"": ""29207381"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32709,curation_candidate,11746,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: toxicity of unnatural RNA derivatives is only a concern/background; study reports stability and RNAi activity, not measured toxicity."", ""grounding_quote"": """", ""source_pmid"": ""23449417"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32710,curation_candidate,11764,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: in silico derisking/prediction of siRNA targets; no observed administered safety/toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""34978699"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32711,curation_candidate,14192,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/3 fail: siRNA is a BUB1B knockdown tool in an aflatoxin hepatocarcinogenesis study; toxicity belongs to AFB1/model, not therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""40147685"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32712,curation_candidate,14201,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of Lp(a) therapies and future safety concerns; no primary toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""40127045"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32713,curation_candidate,14203,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: siRNA nanoradiosensitizer readouts are tumor DNA damage/immunogenic cell death for efficacy, not safety toxicity."", ""grounding_quote"": """", ""source_pmid"": ""40125668"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32714,curation_candidate,14209,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review summarizing imetelstat efficacy and adverse effects; no primary source toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""40116730"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32715,curation_candidate,14228,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: excerpt discusses delivery/exposure advantages for apoC-III ASO/siRNA therapies but no toxicity or tolerability endpoint."", ""grounding_quote"": """", ""source_pmid"": ""40068508"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32716,curation_candidate,14241,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: KDM5B inhibition/shRNA are cancer biology tools; no therapeutic oligo safety endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""40054828"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32717,curation_candidate,14246,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: inclisiran is mentioned as LDL-C therapy, but no observed toxicity/safety endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""40043177"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32718,curation_candidate,14260,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: RNAi is used for insect stress biology/agricultural context, not a therapeutic oligo under study."", ""grounding_quote"": """", ""source_pmid"": ""40015891"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32719,curation_candidate,14264,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: RNAi is for soybean cyst nematode control/agriculture, not human/therapeutic oligo safety."", ""grounding_quote"": """", ""source_pmid"": ""40015834"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32720,curation_candidate,14269,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of miRNA/ASO promise and possible side effects; no primary toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""40010509"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32721,curation_candidate,14283,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2/3 fail: excerpt gives rationale/design for PNA pretargeting to reduce radiation exposure but no measured toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39986477"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32722,curation_candidate,14287,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: ASO data support antitumor efficacy; 'seemingly nontoxic' is a vague conclusion without a reported safety endpoint."", ""grounding_quote"": """", ""source_pmid"": ""39971224"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32723,curation_candidate,14293,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: workshop/gene-therapy/genomics discussion, not an oligo toxicity primary result."", ""grounding_quote"": """", ""source_pmid"": ""39969133"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32724,curation_candidate,14302,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: Pulsatilla saponin D is a small molecule/natural product and siRNA is only a mechanistic knockdown tool."", ""grounding_quote"": """", ""source_pmid"": ""39954838"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32725,curation_candidate,14311,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: morpholino conjugates regulate an AAV transgene switch, but the passage reports induction performance rather than toxicity."", ""grounding_quote"": """", ""source_pmid"": ""39939797"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32726,curation_candidate,14314,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: bibliometric review of RNAi pest control; agricultural RNAi is out of scope and no primary toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39933636"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32727,curation_candidate,14317,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: antisense morpholino is an in vitro splice-switch research tool for ECFC biology, not therapeutic oligo safety."", ""grounding_quote"": """", ""source_pmid"": ""39928918"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.236908+00:00
32728,curation_candidate,14318,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review/background on Lp(a) pharmacology; no primary oligonucleotide toxicity endpoint in excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39928714"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32729,curation_candidate,14319,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: toxicity is caused by herbicide 2,4-D; no therapeutic oligo is under study."", ""grounding_quote"": """", ""source_pmid"": ""39921193"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32730,curation_candidate,14329,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: AsO43- is arsenate chemistry notation/probe target, not antisense oligonucleotide therapy."", ""grounding_quote"": """", ""source_pmid"": ""39892359"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32731,curation_candidate,14332,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: herbal decoction/nephropathy study; no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""39889489"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32732,curation_candidate,14337,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO means arteriosclerosis obliterans/vascular disease context, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""39864510"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32733,curation_candidate,14344,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: shRNA-encoded nanoparticle is excluded shRNA/gene-silencing vector context; no in-scope therapeutic oligo toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""39842735"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32734,curation_candidate,14360,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: aptamer/SNA system is a diagnostic food-safety assay, not therapeutic oligo toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""39806115"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32735,curation_candidate,14363,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: FGF21 protein and beta-Klotho knockdown are not therapeutic oligonucleotide agents."", ""grounding_quote"": """", ""source_pmid"": ""39798471"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32736,curation_candidate,14366,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: knockdown/autophagy assays are disease-mechanism tools, not therapeutic oligo safety."", ""grounding_quote"": """", ""source_pmid"": ""39789715"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32737,curation_candidate,14379,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of nucleic acid SERS sensing applications; no primary therapeutic oligo toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39749546"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32738,curation_candidate,14380,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: siRNA screening is used to identify deubiquitination enzymes in arterial stiffness biology, not as a therapeutic under safety study."", ""grounding_quote"": """", ""source_pmid"": ""39742393"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32739,curation_candidate,14394,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: aptasensor is an analytical detection platform, not a therapeutic aptamer/oligo."", ""grounding_quote"": """", ""source_pmid"": ""39643297"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32740,curation_candidate,14396,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO refers to arterial switch operation, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""39617321"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32741,curation_candidate,14401,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: As(V) is arsenic chemistry, not an oligonucleotide therapeutic."", ""grounding_quote"": """", ""source_pmid"": ""39561542"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32742,curation_candidate,14402,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/3 fail: oligonucleotide is a DNA-binding reagent for FOXJ1 protein; toxicity concerns recombinant protein/E. coli burden, not oligo safety."", ""grounding_quote"": """", ""source_pmid"": ""39549898"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32743,curation_candidate,14406,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: cocaine aptamer is a diagnostic sensor component, not therapeutic oligo toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""39522276"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32744,curation_candidate,14414,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: siFA2H is a research knockdown reagent in breast cancer cell migration, not therapeutic under study."", ""grounding_quote"": """", ""source_pmid"": ""39468429"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32745,curation_candidate,14418,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: systematic review of RNAi hypertension therapies and safety profile; no primary toxicity result in excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39400663"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32746,curation_candidate,14422,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: oligonucleotide aptamers are detection reagents for mycotoxin assays, not therapeutics."", ""grounding_quote"": """", ""source_pmid"": ""39298849"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32747,curation_candidate,14424,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: QYYYG is an herbal granule and siRNAs are mechanistic Nrf2 knockdown tools."", ""grounding_quote"": """", ""source_pmid"": ""39278297"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32748,curation_candidate,14427,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO denotes arteriosclerosis obliterans patients, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""39231729"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.237916+00:00
32749,toxicity_endpoint,1448,human_curator_expand,apply_script.py,curator_verified,accept,ql,"{""reason"": ""Bepirovirsen sequential therapy reports comparable adverse-event proportions and is described as tolerable."", ""grounding_quote"": ""The proportions of participants with adverse events and treatment-related adverse events in both treatment windows were similar between treatment arms. CONCLUSIONS: Sequential therapy with bepirovirsen followed by Peg-IFN is tolerable"", ""source_pmid"": ""39214467"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.242096+00:00
32750,curation_candidate,14430,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: excerpt reports vutrisiran efficacy outcomes but no safety/toxicity endpoint within the provided passage."", ""grounding_quote"": """", ""source_pmid"": ""39213194"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.242096+00:00
32751,curation_candidate,14431,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of hereditary ataxia emerging therapies; safety is future/general, not a primary toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39153956"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.242096+00:00
32752,curation_candidate,14432,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO means arterial switch operation, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""39048636"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.242096+00:00
32753,curation_candidate,14433,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO means arterial switch operation; passage concerns coronary variants after surgery, not oligo therapy."", ""grounding_quote"": """", ""source_pmid"": ""39004268"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.242096+00:00
32754,curation_candidate,14434,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of Factor XI inhibitors; no primary oligo safety result is reported in this excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38804623"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.242096+00:00
32755,curation_candidate,14438,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: MK-0616 is an oral peptide PCSK9 inhibitor, not an oligonucleotide therapeutic under toxicity study."", ""grounding_quote"": """", ""source_pmid"": ""38285643"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.242096+00:00
32756,curation_candidate,14446,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: xalnesiran safety is mentioned as assessed, but the excerpt reports only efficacy endpoints and no observed safety result."", ""grounding_quote"": """", ""source_pmid"": ""39774313"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.242096+00:00
32757,toxicity_endpoint,1449,human_curator_expand,apply_script.py,curator_verified,accept,ql,"{""reason"": ""TPT-ASOVEGF@MM oligo-containing nanodrug showed antimetastatic activity in mice with minor toxic side effects; toxicity detail is generic so Grade C."", ""grounding_quote"": ""In MBC mouse models, the in vivo inhibition rate of TPT-ASOVEGF@MM NPs for lung metastasis was 89.5%, with minor toxic side effects and the least number of metastatic nodules in the lungs."", ""source_pmid"": ""39657238"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.245388+00:00
32758,curation_candidate,14485,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: alirocumab is a monoclonal antibody and the passage concerns Lp(a) risk/atherosclerosis, not oligo toxicity."", ""grounding_quote"": """", ""source_pmid"": ""39561225"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.245388+00:00
32759,curation_candidate,14490,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of ncRNAs as targets and possible adverse off-target sequelae; no administered primary safety result."", ""grounding_quote"": """", ""source_pmid"": ""39531874"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.245388+00:00
32760,curation_candidate,14492,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: review of CGG repeat disease mechanisms; no therapeutic oligo under observed toxicity study."", ""grounding_quote"": """", ""source_pmid"": ""39523485"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.245388+00:00
32761,curation_candidate,14493,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: siRNA knockdown is a cardiomyocyte mechanism experiment, not therapeutic oligo safety."", ""grounding_quote"": """", ""source_pmid"": ""39520298"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.245388+00:00
32762,toxicity_endpoint,1450,human_curator_expand,apply_script.py,curator_verified,accept,ql,"{""reason"": ""siRNA-loaded lipid-polymer nanoparticles for lung inflammation altered pulmonary surfactant function/structure in vitro, a safety-relevant endpoint."", ""grounding_quote"": ""Here, we investigated the effect of small interfering RNA (siRNA)-loaded lipid-polymer hybrid nanoparticles (LPNs), which are designed for treatment of lung inflammation, on the physiological function of PS. By using biophysical in vitro methods we show that siRNA-loaded LPNs affect the biophysical function and lateral structure of PS."", ""source_pmid"": ""39491068"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.248910+00:00
32763,curation_candidate,14499,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/3 fail: toxicity is from hexavalent chromium and siRNA silencing is mechanistic rescue, not therapeutic oligo safety."", ""grounding_quote"": """", ""source_pmid"": ""39486596"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.248910+00:00
32764,curation_candidate,14504,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: fusion dsRNAs are for arthropod pest control/agriculture, out of therapeutic oligo scope."", ""grounding_quote"": """", ""source_pmid"": ""39477575"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.248910+00:00
32765,curation_candidate,14508,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: trans-omics/sepsis gene validation has no therapeutic oligonucleotide agent under study."", ""grounding_quote"": """", ""source_pmid"": ""39471899"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.248910+00:00
32766,curation_candidate,14509,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: special report/review of plozasiran and zodasiran trials; no primary safety/toxicity endpoint in excerpt."", ""grounding_quote"": """", ""source_pmid"": ""39469883"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.248910+00:00
32767,toxicity_endpoint,1451,human_curator_expand,apply_script.py,curator_verified,accept,ql,"{""reason"": ""Dll4-targeting siRNA liposomal system was evaluated for safety with favorable outcomes and minimal off-target effects; toxicity support is generic so Grade C."", ""grounding_quote"": ""By employing liposomes for siRNA delivery, we observed enhanced stability and specificity of the siRNA. Alongside the therapeutic efficacy, our study also evaluated the safety profile and pharmacokinetics of the dual-targeted liposomal system, revealing favorable outcomes with minimal off-target effects and optimal biodistribution."", ""source_pmid"": ""39392531"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.253423+00:00
32768,curation_candidate,14529,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of RNA modulation in HPV cervical cancer; no primary toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""39357186"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.253423+00:00
32769,curation_candidate,14531,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: Goldspire/IMV-001 passage reports efficacy and immune activation, not a safety/toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39349152"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.253423+00:00
32770,curation_candidate,14540,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review/real-world summary of inclisiran safety and efficacy; not a primary toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39331729"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.253423+00:00
32771,toxicity_endpoint,1452,human_curator_expand,apply_script.py,curator_verified,accept,ql,"{""reason"": ""Imdusiran is an siRNA therapeutic and did not stimulate cytokine release in healthy donor whole blood."", ""grounding_quote"": ""Imdusiran did not intrinsically stimulate cytokine release in healthy donor human whole blood, supportive of its mechanism of action"", ""source_pmid"": ""39306863"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.257446+00:00
32772,curation_candidate,14552,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO is a Behcet biomarker/anti-streptolysin O context, not antisense oligonucleotide therapy."", ""grounding_quote"": """", ""source_pmid"": ""39290014"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.257446+00:00
32773,curation_candidate,14562,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO is amino-modified silicone oil in cosmetic pigment, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""39233175"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.257446+00:00
32774,curation_candidate,14564,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: siRNA is a host-factor validation tool in PEDV invasion biology, not therapeutic oligo safety."", ""grounding_quote"": """", ""source_pmid"": ""39233171"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.257446+00:00
32775,curation_candidate,14566,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: Huperzine A is a small molecule/natural product and siRNA-Apoe is a validation tool."", ""grounding_quote"": """", ""source_pmid"": ""39233057"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.257446+00:00
32776,curation_candidate,14583,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: olpasiran passage states safety objective but excerpted results stop at Lp(a) efficacy; no toxicity endpoint reported."", ""grounding_quote"": """", ""source_pmid"": ""39168564"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.257446+00:00
32777,curation_candidate,14603,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: adverse dyslipidemia is attributed to everolimus and the excerpt never reports inclisiran safety/toxicity."", ""grounding_quote"": """", ""source_pmid"": ""39102576"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.257446+00:00
32778,curation_candidate,14616,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: review of hearing-loss therapies/CRISPR; no therapeutic oligo toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39051644"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.258449+00:00
32779,curation_candidate,14617,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: RLIP antisense causes ovarian cancer cell killing and xenograft remission as efficacy, not safety toxicity."", ""grounding_quote"": """", ""source_pmid"": ""39051454"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.258449+00:00
32780,curation_candidate,14622,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of ANGPTL3 blockade and safety profiles; no primary observed toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39039670"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.258449+00:00
32781,curation_candidate,14623,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: ASO refers to arterial switch operation in valve replacement patients, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""39033329"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.258449+00:00
32782,curation_candidate,14624,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: Withaferin A is a small molecule and siRNA is mechanistic knockdown, not therapeutic oligo safety."", ""grounding_quote"": """", ""source_pmid"": ""39032282"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.258449+00:00
32783,curation_candidate,14637,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/3 fail: siRNA-mediated knockdown is a GBM functional validation tool and cell viability is cancer efficacy, not safety toxicity."", ""grounding_quote"": """", ""source_pmid"": ""38996666"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.258449+00:00
32784,curation_candidate,14646,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of cardiovascular nucleic-acid therapies; no primary safety endpoint in excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38970537"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.258449+00:00
32785,toxicity_endpoint,1453,human_curator_expand,apply_script.py,curator_verified,accept,ql,"{""reason"": ""HGF DNA aptamer is the therapeutic oligo under study and the abstract reports biosafety, but endpoint detail is generic so Grade C."", ""grounding_quote"": ""Due to its therapeutic benefits, excellent stability, biosafety, cost-effectiveness, and versatility, the HGF DNA aptamer demonstrates promise for preventing PPA in future clinical settings."", ""source_pmid"": ""38963794"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32786,curation_candidate,14650,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: heavy-metal remediation nanocomposite has no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""38943880"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32787,curation_candidate,14663,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: literature review of nonstatin cholesterol agents; no primary oligo toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38912991"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32788,curation_candidate,14665,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: passage recaps a recent fesomersen phase 2 safety profile rather than reporting a primary result from this article."", ""grounding_quote"": """", ""source_pmid"": ""38906653"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32789,curation_candidate,14670,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1/2 fail: chapter/review includes mRNA vaccines and RNA products; no primary therapeutic oligo toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""38888787"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32790,curation_candidate,14676,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of siRNA therapy challenges in ALL; safety statements are generic, not primary observed endpoints."", ""grounding_quote"": """", ""source_pmid"": ""38874790"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32791,curation_candidate,14688,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: scoping review extracting trial data/adverse events; not a primary toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""38830793"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32792,curation_candidate,14690,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 1 fail: methotrexate transport study uses siRNAs as transporter tools; MTX is the drug under study."", ""grounding_quote"": """", ""source_pmid"": ""38823222"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32793,curation_candidate,14695,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: siRNA treatment reports antinociceptive efficacy, while side effects belong to SNX-482/morphine rather than the oligo."", ""grounding_quote"": """", ""source_pmid"": ""38812100"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32794,curation_candidate,14700,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 3 fail: zodasiran trial methods mention safety evaluation, but provided passage reports no observed safety/toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""38809174"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32795,curation_candidate,14704,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review/expert perspective on inclisiran discovery with favorable safety profile; no primary toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""38804735"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32796,curation_candidate,14705,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: broad antihypertensive drug review with no primary oligo safety endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38798249"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32797,curation_candidate,14706,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of preclinical biotherapeutic assessment; no primary siRNA-antibody conjugate toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""38797272"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32798,curation_candidate,14713,human_curator_expand,apply_script.py,curator_rejected,reject,ql,"{""reason"": ""GATE 2 fail: review of CGG repeat therapies; no observed oligo toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38780719"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32799,curation_candidate,14721,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: review/future-facing HD passage mentions long-term safety assessments but reports no observed oligo toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""38764004"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32800,curation_candidate,14723,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: passage studies BPDE environmental toxicant; Nrf2 siRNA is a mechanistic tool, not the therapeutic under study."", ""grounding_quote"": """", ""source_pmid"": ""38759404"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32801,curation_candidate,14727,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: DLGAP1-AS2 siRNA is used for gastric cancer chemosensitization; cell viability/apoptosis are efficacy cancer readouts, not safety toxicity."", ""grounding_quote"": """", ""source_pmid"": ""38748228"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32802,curation_candidate,14733,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: review of RNA medicine platforms; safety profiles are discussed generally with no primary observed toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""38740953"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32803,curation_candidate,14735,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: wastewater antimony photocatalyst study with no therapeutic oligonucleotide under study."", ""grounding_quote"": """", ""source_pmid"": ""38734246"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32804,curation_candidate,14736,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: review of ncRNA therapeutic strategies in HCC; safety is a clinical-development concern, not an observed endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38728793"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.261447+00:00
32805,toxicity_endpoint,1454,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Therapeutic PS-ASO had low hemolysis and no toxic manifestations in normal rats; abstract-only generic ASO support so Grade C."", ""grounding_quote"": ""PS-ASO showed low in vitro hemolysis (<3 %), and had a sustained PS-ASO blood residence time in vivo compared to DTX, with a time-dependent hepatic uptake. It showed no toxic manifestations in normal rats."", ""source_pmid"": ""38697280"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.265474+00:00
32806,curation_candidate,14746,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: DNA walker platform reports delivery/gene silencing and vague biosafety, but no measured toxicity or tolerability endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38686696"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.265474+00:00
32807,curation_candidate,14755,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: patient-perspective clinical-study passage discusses adverse-event communication but no therapeutic oligonucleotide is under study."", ""grounding_quote"": """", ""source_pmid"": ""38670885"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.265474+00:00
32808,toxicity_endpoint,1455,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Named tofersen ASO was administered and side effects were reported as minimal; abstract-only named oligo support so Grade B."", ""grounding_quote"": ""the patient received monthly intrathecal treatment with tofersen, an antisense oligonucleotide compound that inhibits SOD1 protein expression and hence lowers the synthesis of toxic SOD1 protein species. Side effects have been minimal and mostly attributed to the spinal taps."", ""source_pmid"": ""38666665"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.269017+00:00
32809,curation_candidate,14759,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: ssDNA oligonucleotides are diagnostic biosensor probes, not therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""38660999"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.269017+00:00
32810,curation_candidate,14773,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: arsenic retention/co-gasification study has no therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""38598878"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.269626+00:00
32811,curation_candidate,14780,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: comprehensive review of RNA therapeutics for metabolic syndrome; no primary observed toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""38580818"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.269626+00:00
32812,curation_candidate,14790,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: inclisiran expert-opinion review discusses safety analyses but gives no observed safety outcome in this passage."", ""grounding_quote"": """", ""source_pmid"": ""38549399"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.269626+00:00
32813,toxicity_endpoint,1456,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Named patisiran RNAi therapeutic trial subanalysis reports acceptable safety; abstract-only named oligo support so Grade B."", ""grounding_quote"": ""BACKGROUND: To examine the efficacy and safety of patisiran, an RNA interference therapeutic, in patients from Taiwan with hereditary transthyretin-mediated (hATTR) amyloidosis with polyneuropathy. METHODS: The APOLLO phase 3 trial included patients from Taiwan who received patisiran 0.3 mg/kg intravenously or placebo once every 3 weeks (q3w) for 18 months (18 M), followed by patisiran 0.3 mg/kg q3w in an ongoing global open-label extension (OLE) study. The primary endpoint was change from baseline in modified Neuropathy Impairment Score +7 (mNIS+7) at 18 M. RESULTS: Eighteen Taiwanese patients were enrolled in APOLLO (patisiran, n = 8; placebo, n = 10; all A97S gene variant) and 14 continued in the global OLE. In this Taiwanese sub-population, beneficial treatment effects at 18 M were observed in mNIS+7 (least squares mean difference in change from baseline [patisiran-placebo], -26.5 points; 95% confidence interval: -45.5, -7.5). Patients who switched from placebo to patisiran demonstrated slowing of polyneuropathy progression at month 12 in the global OLE, while those who received patisiran in APOLLO maintained the beneficial treatment effects. Patisiran had an acceptable safety"", ""source_pmid"": ""38548524"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32814,curation_candidate,14796,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: chronic hepatitis B passage concerns nucleoside/nucleotide analogs and other therapies, not a therapeutic oligo toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""38547374"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32815,curation_candidate,14805,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: SpyCas9 aptamer is a CRISPR-control reagent and the passage reports inhibition, not oligo-linked toxicity."", ""grounding_quote"": """", ""source_pmid"": ""38479030"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32816,curation_candidate,14814,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: DPP7 siRNA knockdown is an experimental tool in CRC cells, not a therapeutic oligo under safety evaluation."", ""grounding_quote"": """", ""source_pmid"": ""38454764"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32817,curation_candidate,14823,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: DNA nanomachine excerpt reports cancer imaging/chemo-gene therapy design and efficacy, not a measured toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38441369"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32818,curation_candidate,14844,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: viltolarsen review summarizes trial findings; review/prior-work recap is not a primary result passage."", ""grounding_quote"": """", ""source_pmid"": ""38376743"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32819,curation_candidate,14846,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: review of ANGPTL3/ApoC-III inhibitors reports lipid efficacy, not primary oligo toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""38372218"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32820,curation_candidate,14847,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: review of kallikrein inhibitors; tolerability is not a primary ASO-linked toxicity result in this passage."", ""grounding_quote"": """", ""source_pmid"": ""38366937"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32821,curation_candidate,14853,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: review of RNA therapeutics for blood disorders; safe delivery/off-target effects are challenges, not observed toxicity endpoints."", ""grounding_quote"": """", ""source_pmid"": ""38360003"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32822,curation_candidate,14854,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: overview of RNA therapeutics for excretory disorders; no primary toxicity result is reported."", ""grounding_quote"": """", ""source_pmid"": ""38360001"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32823,curation_candidate,14855,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: metabolic-disorder RNA therapeutics review mentions clinical safety generally but no specific observed toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38359998"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.274686+00:00
32824,toxicity_endpoint,1457,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Anti-miR-33 DNA origami therapeutic reports a validated safety profile in an AS mouse model; toxicity detail is generic so Grade C."", ""grounding_quote"": ""The antiatherosclerotic efficacy and safety profile of cRGD/ASOtDON, as well as its mechanism of action, were validated in an AS mouse model."", ""source_pmid"": ""38321605"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.278208+00:00
32825,curation_candidate,14873,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: LDH-AMO passage lists biocompatibility assays but does not report an observed safety/toxicity result in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38311162"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32826,curation_candidate,14883,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: review of gene-based approaches for diabetic hepatic complications; safety challenges are discussed, not measured."", ""grounding_quote"": """", ""source_pmid"": ""38281457"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32827,curation_candidate,14885,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: vutrisiran drug-discovery review/case history summarizes HELIOS-A safety, not a primary result passage."", ""grounding_quote"": """", ""source_pmid"": ""38281068"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32828,curation_candidate,14886,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: xenotransplantation/PERV review mentions siRNA as a prevention strategy but no oligo-linked toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""38281060"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32829,curation_candidate,14888,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: SARS-CoV-2/phosphate disease-mechanism study with no therapeutic oligo under study."", ""grounding_quote"": """", ""source_pmid"": ""38275129"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32830,curation_candidate,14898,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: PCR primers/probes are diagnostic oligos, not therapeutic agents."", ""grounding_quote"": """", ""source_pmid"": ""38226743"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32831,curation_candidate,14913,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: RAD51 siRNA is a research knockdown tool and radiosensitization/cytocidal effects are cancer efficacy, not toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""38159995"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32832,curation_candidate,14917,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: ASO here is Annals of Surgical Oncology perspective, not antisense oligonucleotide; toxicity concerns T-DM1 chemotherapy."", ""grounding_quote"": """", ""source_pmid"": ""38127215"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32833,curation_candidate,14921,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: ncRNA/GBM chemoresistance review; no therapeutic oligo safety endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""38086292"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32834,curation_candidate,14924,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: TET3 siRNA is a photoaging-model knockdown tool, not a therapeutic oligo under study."", ""grounding_quote"": """", ""source_pmid"": ""38054565"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32835,curation_candidate,14929,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: Lp(a) review reports ASO lipid-lowering efficacy and risk background, not toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""37997792"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32836,curation_candidate,14939,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: glaucoma review summarizes prior gene/siRNA studies; few adverse effects are not a primary result passage here."", ""grounding_quote"": """", ""source_pmid"": ""37910173"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32837,curation_candidate,14953,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: editorial/commentary describes another ARO-APOC3 trial and gives no observed safety outcome in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""38320508"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32838,curation_candidate,14955,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: ASO means arteriosclerosis obliterans in this passage, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""38279498"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32839,curation_candidate,14961,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: endosomal-escape molecule passage gives design/background claims and no measured toxicity endpoint linked to an oligo product."", ""grounding_quote"": """", ""source_pmid"": ""38133698"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32840,curation_candidate,14963,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: review of severe hypertriglyceridemia inhibitors; no primary oligo toxicity result is reported."", ""grounding_quote"": """", ""source_pmid"": ""38095804"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32841,curation_candidate,14973,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: inclisiran trial excerpt reports LDL-C efficacy while safety is only assessed, with no toxicity outcome shown."", ""grounding_quote"": """", ""source_pmid"": ""38016401"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32842,curation_candidate,14980,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: Salmonella aptamer/CRISPR assay is diagnostic, not therapeutic."", ""grounding_quote"": """", ""source_pmid"": ""37996158"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32843,curation_candidate,14982,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: tricyclo-DNA ASO passage concerns renal clearance/PK and efficacy, not renal toxicity."", ""grounding_quote"": """", ""source_pmid"": ""37967388"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32844,curation_candidate,14991,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: ovarian-cancer RNA therapeutics review summarizes preclinical/clinical work and mRNA vaccines; no primary oligo toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""37916491"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.279208+00:00
32845,toxicity_endpoint,1458,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Self-assembled spherical nucleic acid gene-silencing therapeutics are reported as non-toxic; generic in vitro support so Grade C."", ""grounding_quote"": ""Disulfide-crosslinked SNAs combine these two properties and result in efficient and non-toxic unaided gene silencing therapeutics."", ""source_pmid"": ""37905978"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.281208+00:00
32846,curation_candidate,14995,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: cholesterol oligonucleotides and aptamers are viral-detection reagents, not therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""37901936"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.281208+00:00
32847,curation_candidate,15009,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: CD274 siRNA/lenti-sh are knockdown or vector tools in a cuproptosis strategy, not oligo therapeutics with safety evidence."", ""grounding_quote"": """", ""source_pmid"": ""37828105"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.281208+00:00
32848,curation_candidate,15018,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: inclisiran real-world registry excerpt reports LDL-C efficacy only; no safety/toxicity outcome is present."", ""grounding_quote"": """", ""source_pmid"": ""37775462"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.281208+00:00
32849,curation_candidate,15030,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: vutrisiran review summarizes tolerability/adverse events from a pivotal study, not a primary result passage."", ""grounding_quote"": """", ""source_pmid"": ""37728865"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.281208+00:00
32850,curation_candidate,15033,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: patulin aptasensor oligonucleotides are diagnostic/food-safety reagents, not therapeutic agents."", ""grounding_quote"": """", ""source_pmid"": ""37725068"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.281208+00:00
32851,curation_candidate,15038,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: hypertension RNA-therapeutics review reports efficacy concepts and no toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""37706295"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.281208+00:00
32852,curation_candidate,15054,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: siRNA and expression vectors are mechanistic tools in colorectal cancer radioresistance, not therapeutic oligos under safety study."", ""grounding_quote"": """", ""source_pmid"": ""37594135"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.282713+00:00
32853,curation_candidate,15059,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: dyslipidemia review discusses benefit-risk profiles generally and reports no observed oligo toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""37567512"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.282713+00:00
32854,curation_candidate,15110,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: ASO ADME review discusses factors affecting safety profiles, not a primary observed toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""37076460"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.282713+00:00
32855,curation_candidate,15158,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: protocol for prodrug-type oligonucleotide synthesis; adverse-effect reduction is design rationale, not measured toxicity."", ""grounding_quote"": """", ""source_pmid"": ""40192303"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.282713+00:00
32856,toxicity_endpoint,1459,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""PD-L1 siRNA nanoparticle treatment reported sparing adjacent T cells, a safety-sense cytotoxicity endpoint; boundary abstract support so Grade C."", ""grounding_quote"": ""Here it develops a 10B-containing polymer that self-assembled with PD-L1 siRNA to form 10B/siPD-L1 nanoparticles for combinational BNCT-immunotherapy. Unlike antibodies, PD-L1 siRNA can inhibit intracellular PD-L1 upregulated by BNCT, activating T-cell immunity while also suppressing DNA repair. This can enhance BNCT-induced DNA damage, promoting immunogenic cell death (ICD) and further amplifying the antitumor immune effect. The results demonstrated that BNCT using 10B/siPD-L1 nanoparticles precisely killed tumor cells while sparing adjacent T cells"", ""source_pmid"": ""39955653"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.284718+00:00
32857,toxicity_endpoint,1460,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""Named oligonucleotide PROTACs MP-16/MP-17 inhibited tumors and exhibited promising drug safety in mice; weak safety detail so Grade C."", ""grounding_quote"": ""Herein, by conjugating VH032 with an optimized DNA sequence that recognized c-Myc complex, we discovered oligonucleotide-based proteolysis targeting chimeras (PROTACs), termed as MP-16 and MP-17, which effectively induced degradation of c-Myc. Mechanically, MP-16 or MP-17 directly interacted with c-Myc complex to form VHL/PROTAC/c-Myc ternary complex, and triggered c-Myc degradation by recruiting ubiquitin-proteasome system, suppressing cell proliferation of HCC cells. In mice model, MP-16 or MP-17 significantly inhibited HCC tumor growth and exhibited promising drug safety."", ""source_pmid"": ""39447458"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32858,curation_candidate,15209,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: siPAI-1 nanoparticle passage reports delivery and ovarian efficacy; safe nanomaterials are background, not a toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39216744"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32859,curation_candidate,15217,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: ophthalmic LNP review discusses possible risks but gives no primary observed safety endpoint."", ""grounding_quote"": """", ""source_pmid"": ""39067162"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32860,curation_candidate,15226,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: antisense-technology de-risking is a platform statement, not a measured toxicity/tolerability result."", ""grounding_quote"": """", ""source_pmid"": ""37354903"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32861,curation_candidate,15245,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: RNAi nanotherapeutics review discusses delivery barriers and renal clearance, not toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""32902291"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32862,curation_candidate,15252,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: oligonucleotides are MS structural-analysis substrates; safety of therapeutics is background, not an endpoint."", ""grounding_quote"": """", ""source_pmid"": ""32346915"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32863,curation_candidate,15272,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: half-life/biophase modeling is PK/PD dose reasoning, not a toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""30328765"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32864,curation_candidate,15281,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: white paper on oligonucleotide impurities and safety thresholds; no observed toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""29125795"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32865,curation_candidate,15303,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: siRNA transfection is a glioblastoma research tool, not a therapeutic oligo under safety evaluation."", ""grounding_quote"": """", ""source_pmid"": ""31960992"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32866,curation_candidate,15404,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: siSLU7 aptamer/nanoparticle passage describes cancer-targeting strategy but no toxicity or tolerability endpoint in the excerpt."", ""grounding_quote"": """", ""source_pmid"": ""41337884"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32867,curation_candidate,15423,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: RSV/IL-33 barrier-mechanism study has no therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""40497542"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32868,curation_candidate,15424,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: GADD45B siRNA and AAV-shRNA are disease-model perturbation tools, not therapeutic oligos under safety study."", ""grounding_quote"": """", ""source_pmid"": ""40485526"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32869,curation_candidate,15425,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: postsurgical-pain mechanism passage has no therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""40482455"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32870,curation_candidate,15440,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: HDAC6 siRNA is a mechanistic knockdown tool and ACY1215 is a small-molecule inhibitor."", ""grounding_quote"": """", ""source_pmid"": ""40414514"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32871,curation_candidate,15441,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: siRNA-mediated primary-cilium modulation is a radiation-bystander research tool, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""40412783"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32872,curation_candidate,15446,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: DPO-PCR uses diagnostic oligonucleotides; adverse effects belong to antibiotic regimens, not oligo therapy."", ""grounding_quote"": """", ""source_pmid"": ""40400051"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32873,curation_candidate,15454,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: siRNA-mediated DDIT3 manipulation is an experimental tool in breast cancer cells."", ""grounding_quote"": """", ""source_pmid"": ""40359764"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.290293+00:00
32874,curation_candidate,15488,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: NAPSA siRNA transfection is an in vitro ccRCC tool, not a therapeutic oligo under safety evaluation."", ""grounding_quote"": """", ""source_pmid"": ""40194687"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32875,curation_candidate,15500,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: precision-nutrition review discusses siRNA potential and challenges, not primary toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""40158690"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32876,curation_candidate,15501,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: safety profile is for risdiplam, a small molecule; nusinersen is only mentioned as prior switched therapy."", ""grounding_quote"": """", ""source_pmid"": ""40153113"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32877,curation_candidate,15524,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: RNAi interference in fish immunity is a biological tool/agricultural-style model, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""40073091"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32878,curation_candidate,15536,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: shrimp RNAi knockdown in WSSV biology is not a therapeutic oligo under study."", ""grounding_quote"": """", ""source_pmid"": ""40020951"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32879,curation_candidate,15546,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: dsRNA/RNAi in cotton aphid coevolution is agricultural/insect RNAi, explicitly out of scope."", ""grounding_quote"": """", ""source_pmid"": ""39992628"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32880,curation_candidate,15588,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: ZNF703 knockdown/cisplatin sensitization is a cancer research manipulation, not therapeutic oligo safety evidence."", ""grounding_quote"": """", ""source_pmid"": ""39828065"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32881,curation_candidate,15602,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: TNIP2 siRNA is a mechanistic tool; toxicity result concerns small-molecule icariside II, not an oligo."", ""grounding_quote"": """", ""source_pmid"": ""39775470"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32882,curation_candidate,15604,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: DNA nanomaterials review discusses safety concerns and potential, not a primary observed endpoint."", ""grounding_quote"": """", ""source_pmid"": ""39745199"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32883,curation_candidate,15607,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: capsaicin aptamer lateral-flow assay is diagnostic/food-analysis use, not therapeutic."", ""grounding_quote"": """", ""source_pmid"": ""39731823"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32884,curation_candidate,15614,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: HMGB3 silencing is cancer-mechanism manipulation and no therapeutic oligo is under safety study."", ""grounding_quote"": """", ""source_pmid"": ""39660968"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32885,curation_candidate,15619,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: DNA aptamer quantum-dot lateral-flow assay detects toxins; it is not therapeutic."", ""grounding_quote"": """", ""source_pmid"": ""39578342"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32886,curation_candidate,15622,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: chloramphenicol aptasensor is an analytical assay, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""39522467"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32887,curation_candidate,15628,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: siRNA is used as a mechanistic tool for TFA small-molecule effects, not as the therapeutic under study."", ""grounding_quote"": """", ""source_pmid"": ""39289944"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32888,curation_candidate,15629,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: WEE1/SLC7A11 siRNAs are mechanistic inhibitors in lung cancer cells, not therapeutic oligo safety evidence."", ""grounding_quote"": """", ""source_pmid"": ""39245684"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32889,curation_candidate,15634,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: Drosophila RNAi and KU-60019 geroprotection are not therapeutic oligo toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""39970115"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32890,curation_candidate,15648,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: p53 siRNA is a mechanistic tool; toxicity mitigation is attributed to rutin, not an oligo."", ""grounding_quote"": """", ""source_pmid"": ""39642313"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32891,curation_candidate,15661,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: Foxo3 siRNAs are mechanistic tools and AKBA is the small-molecule treatment under biosafety discussion."", ""grounding_quote"": """", ""source_pmid"": ""39510032"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32892,curation_candidate,15667,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: hirsutine is a small molecule; no therapeutic oligonucleotide is under study."", ""grounding_quote"": """", ""source_pmid"": ""39437684"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32893,curation_candidate,15669,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 3 fail: aptamer-conjugated CPA-AG product is described, but the excerpt reports no observed toxicity endpoint linked to it."", ""grounding_quote"": """", ""source_pmid"": ""39414093"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32894,curation_candidate,15674,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: pSMP-EzH2 shRNA plasmid is vector-expressed shRNA, which is out of scope; no toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""39363829"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32895,curation_candidate,15682,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: GR siRNA is a mechanistic tool and rice bran/oryzanol is the intervention, not an oligo therapeutic."", ""grounding_quote"": """", ""source_pmid"": ""39310986"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.291294+00:00
32896,toxicity_endpoint,1461,human_curator_expand,apply_script.py,curator_verified,accept,sm,"{""reason"": ""siCD98-loaded nanoparticles had biocompatibility and biosafety evaluated with good in vitro and in vivo results; generic support so Grade C."", ""grounding_quote"": ""The nano-bomb nanoparticles were validated for their ability to load CD98 siRNA (siCD98) and Annexin A1-mimetic peptides (Ac2-26 peptides), as well as release CO2 upon lysosomal escape. Surface modification with hyaluronic acid (HA) was assessed for its capability to target inflammatory tissues and cells. Biocompatibility and biosafety were evaluated through in vitro and in vivo studies. The anti-inflammatory and pro-resolving effects of siCD98@NPs and Ac2-26@NPs, both individually and in combination, were evaluated by measuring ROS production, pro-inflammatory cytokine expression, CD98 gene expression, and macrophage polarization. Results: These nanoparticles could efficiently load siCD98 and Ac2-26 peptides and release CO2 under acidic pH in the endo/lysosome to deliver drugs to the cytoplasm. HA could effectively target the inflammatory tissue and cells, showing good biocompatibility and biosafety both in vitro and in vivo."", ""source_pmid"": ""39264298"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32897,curation_candidate,15702,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 1 fail: S. aureus aptamer/CRISPR assay is diagnostic and food-safety oriented, not therapeutic."", ""grounding_quote"": """", ""source_pmid"": ""39163781"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32898,curation_candidate,15704,human_curator_expand,apply_script.py,curator_rejected,reject,sm,"{""reason"": ""GATE 2 fail: dendrimer/gene-silencing RNA review discusses reduced side effects generally, not a primary observed toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""39161976"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32899,curation_candidate,15706,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: PNA/ssDNA components are used in a metal-ion sensor, not as a therapeutic oligonucleotide under study."", ""grounding_quote"": """", ""source_pmid"": ""39141323"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32900,curation_candidate,15710,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: RNAi-mediated silencing is used in tobacco metal-homeostasis biology, not as a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""39085042"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32901,curation_candidate,15711,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: passage is about antibody-drug conjugates and a special-issue preface, with no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""39073838"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32902,curation_candidate,15715,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: oligonucleotide is part of an aptasensor for biotoxin detection, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""38990678"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32903,curation_candidate,15722,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: Serenade ASO is a Bacillus control product acronym, not an antisense oligonucleotide therapy."", ""grounding_quote"": """", ""source_pmid"": ""38053437"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32904,curation_candidate,15726,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: ASO means arterial switch operation, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""37609811"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32905,curation_candidate,15727,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review/background summary of ANGPTL3 inhibitors; no primary oligo-linked toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""36746257"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32906,curation_candidate,15730,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: passage is a review summary of bepirovirsen phase I/II data, not a primary measured safety result."", ""grounding_quote"": """", ""source_pmid"": ""37902953"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32907,curation_candidate,15732,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: passage is background/proposal for TGF-beta blockade and does not report a primary toxicity result linked to an oligo."", ""grounding_quote"": """", ""source_pmid"": ""37855975"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32908,curation_candidate,15736,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: ASO means arterial switch operation, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""37768214"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32909,curation_candidate,15738,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: ASO is the journal/author-reflection label and the agent is HIFU, not a therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""37749406"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32910,curation_candidate,15742,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of genetic therapies in cystic fibrosis; no primary safety result for an oligo is reported."", ""grounding_quote"": """", ""source_pmid"": ""37700667"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32911,curation_candidate,15756,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: modified oligonucleotides are assay substrates for DNA-adduct mutagenicity, not therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""37486230"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.295812+00:00
32912,curation_candidate,15758,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: environmental remediation material for plastics/metals; no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""37437871"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32913,curation_candidate,15762,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: chitosan/iron oxide/plasma toxicant-removal study; no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""37422214"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32914,curation_candidate,15765,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: FNA/aptamer/siRNA nanosystem reports tumor killing/chemo-gene efficacy, not safety-sense toxicity."", ""grounding_quote"": """", ""source_pmid"": ""37421332"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32915,curation_candidate,15766,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: nucleic acid detection instrument for biomarkers, not a therapeutic oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""37418065"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32916,curation_candidate,15793,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: siRNA is a knockdown tool in fibrosis biology and the safety study concerns CM272, not an oligo therapy."", ""grounding_quote"": """", ""source_pmid"": ""37356504"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32917,curation_candidate,15805,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: WFS1-siRNA is a mechanistic knockdown tool in placental stress biology, not a therapeutic oligo under study."", ""grounding_quote"": """", ""source_pmid"": ""37269649"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32918,curation_candidate,15809,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: siRNA is used to construct knockdown cancer cell lines, not as a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""37244630"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32919,curation_candidate,15810,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: morpholino appears in the chemical name of a sulphide donor, not as a morpholino oligomer therapy."", ""grounding_quote"": """", ""source_pmid"": ""37244121"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32920,curation_candidate,15819,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: aptamer is used in an aquatic-toxin detection assay, not as a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""37207608"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32921,curation_candidate,15823,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: passage is a therapy overview and the adverse effects discussed are corticosteroid-related, not viltolarsen toxicity."", ""grounding_quote"": """", ""source_pmid"": ""37194523"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32922,curation_candidate,15834,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: RNAi is used for termite/pest biocontrol, an excluded agricultural application."", ""grounding_quote"": """", ""source_pmid"": ""37104842"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32923,curation_candidate,15836,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: adenine base editing for knockout pigs is gene editing, not therapeutic oligo safety evidence."", ""grounding_quote"": """", ""source_pmid"": ""37099179"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32924,curation_candidate,15857,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: oligonucleotide probe is used for FISH detection of archaea, not as a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""37000227"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32925,curation_candidate,15869,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review/background on FXI inhibitors; no primary toxicity endpoint for an oligo is reported."", ""grounding_quote"": """", ""source_pmid"": ""36913497"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32926,curation_candidate,15876,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: RNAi-mediated pest management is an excluded agricultural application, not therapeutic oligo evidence."", ""grounding_quote"": """", ""source_pmid"": ""36847083"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32927,curation_candidate,15882,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of FXIa inhibition; no primary oligo-linked toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""36807817"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32928,curation_candidate,15884,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: aptamer fluorescence assay detects pesticide residue, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""36801730"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32929,curation_candidate,15905,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of DMD exon therapy and planned trials; no primary measured safety result is reported."", ""grounding_quote"": """", ""source_pmid"": ""36655939"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32930,curation_candidate,15908,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: nucleic acid platform detects rice false smut, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""36647749"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32931,curation_candidate,15916,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: ASO means atherosclerotic obliterans, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""36584966"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32932,curation_candidate,15919,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: ASO means arterial switch operation, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""36528432"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.296316+00:00
32933,toxicity_endpoint,1462,human_curator_expand,apply_script.py,curator_verified,accept,gr,"{""reason"": ""Named ASO nusinersen treatment is linked to observed increased CSF leukocyte counts; abstract-only support so Grade B."", ""grounding_quote"": ""The most commonly used therapy for SMA, the antisense oligonucleotide nusinersen, is delivered by repeated intrathecal injections. The long-term safety effects of this procedure, however, have not yet been investigated in detail. We here present case reports of three children with SMA in which routine laboratory investigation revealed increased leukocyte counts in cerebrospinal fluid (CSF) collected during the course of nusinersen treatment."", ""source_pmid"": ""36525882"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.300319+00:00
32934,curation_candidate,15928,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: sequence-specific oligonucleotides are HLA typing reagents, not therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""36426572"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.300319+00:00
32935,curation_candidate,15934,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of CNS nucleic-acid delivery; no primary measured toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""36380168"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.300319+00:00
32936,curation_candidate,15937,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: host-cell DNA assay/manufacturing contaminant study; no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""36282232"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.300319+00:00
32937,curation_candidate,15938,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of factor XI inhibitors; no primary oligo-linked toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""36263776"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.300319+00:00
32938,curation_candidate,15940,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: introductory siRNA review; no primary safety or toxicity result is reported."", ""grounding_quote"": """", ""source_pmid"": ""36250252"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.300319+00:00
32939,curation_candidate,15944,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: oligonucleotides are immunoassay reagents for food allergen detection, not therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""35986996"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.300319+00:00
32940,curation_candidate,15957,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: photocatalytic Cr(VI) reduction study; no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""36511348"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.300319+00:00
32941,curation_candidate,15969,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of recent Lp(a) trials; no primary toxicity endpoint is reported in this passage."", ""grounding_quote"": """", ""source_pmid"": ""36345866"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.300319+00:00
32942,curation_candidate,15974,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: clinical nephropathy/HLA-lab study with ASO as a test term, not antisense oligonucleotide therapy."", ""grounding_quote"": """", ""source_pmid"": ""36308187"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32943,curation_candidate,15991,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: RNAi knockdown is used in crab copper-exposure biology, not as a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""36155024"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32944,curation_candidate,15993,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: engineered nanomaterial chemoresistance study; no therapeutic oligonucleotide agent."", ""grounding_quote"": """", ""source_pmid"": ""36106385"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32945,curation_candidate,15999,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: mRNA therapy is excluded and the passage is not primary oligo toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""36064267"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32946,curation_candidate,16001,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review/background on LNA antimiR therapy; no observed safety endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""36040593"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32947,curation_candidate,16004,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: overview of angiotensinogen-targeted ASO/siRNA therapeutics; no primary toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""35963818"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32948,curation_candidate,16012,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: morpholino appears in a buffer name for lead detection, not as a morpholino oligomer therapy."", ""grounding_quote"": """", ""source_pmid"": ""35796101"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32949,curation_candidate,16014,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: oligonucleotide primers are used for ADAMTS13 sequencing, not as therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""35762256"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32950,curation_candidate,16019,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: carnosol/rosemary is the therapeutic candidate and siRNAs are research knockdown tools."", ""grounding_quote"": """", ""source_pmid"": ""35708500"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32951,curation_candidate,16021,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: aptamer effects are platelet-aggregation/thrombus inhibition efficacy; bleeding events belong to the caplacizumab comparator."", ""grounding_quote"": """", ""source_pmid"": ""35662162"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32952,curation_candidate,16023,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: aptamer-Cas biosensor detects live S. aureus, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""35597144"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32953,curation_candidate,16026,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: siRNA micelle safety is only listed as studied; the passage reports no measured toxicity or tolerability result."", ""grounding_quote"": """", ""source_pmid"": ""35502921"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32954,curation_candidate,16032,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review/overview of hATTR gene therapy options; no primary safety endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""35419654"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32955,curation_candidate,16034,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of miRNA-derivative nucleotide drugs; no primary measured toxicity result is reported."", ""grounding_quote"": """", ""source_pmid"": ""35387533"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32956,curation_candidate,16053,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: miRNA extraction platform for diagnostics, not therapeutic oligo safety evidence."", ""grounding_quote"": """", ""source_pmid"": ""35048934"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32957,curation_candidate,16054,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: RNAi-loaded nanotherapeutic reports cancer chemo-immunotherapy efficacy; adverse effects refer to existing HO1 inhibitors."", ""grounding_quote"": """", ""source_pmid"": ""35044699"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32958,curation_candidate,16057,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: aptamer electrochemical sensor detects algal toxin, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""35012307"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32959,curation_candidate,16067,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: in planta RNAi pest resistance is an excluded agricultural application."", ""grounding_quote"": """", ""source_pmid"": ""34713547"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32960,curation_candidate,16070,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: morpholinos are zebrafish knockdown tools in pesticide toxicology, not therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""34525687"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32961,curation_candidate,16073,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: ASO means arterial switch operation, not antisense oligonucleotide."", ""grounding_quote"": """", ""source_pmid"": ""34350824"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32962,curation_candidate,16076,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review/evaluation of inclisiran literature; safety statements are not primary measured results."", ""grounding_quote"": """", ""source_pmid"": ""35025707"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32963,curation_candidate,16078,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review article summarizing casimersen data; no primary toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""34909800"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32964,curation_candidate,16081,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: morpholino appears in a chemical coupling reagent name, not as a morpholino oligomer therapy."", ""grounding_quote"": """", ""source_pmid"": ""34700182"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32965,curation_candidate,16087,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: descriptive theranostic aptamer passage with no primary toxicity endpoint linked to an oligo."", ""grounding_quote"": """", ""source_pmid"": ""34598060"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32966,curation_candidate,16091,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: siRNA is a mechanistic knockdown tool in medaka pollutant toxicology, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""34543669"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32967,curation_candidate,16095,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: article summarizes inclisiran/bempedoic acid efficacy and safety; no primary toxicity result is reported."", ""grounding_quote"": """", ""source_pmid"": ""34431634"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32968,curation_candidate,16103,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of volanesorsen; the passage does not provide a primary measured toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""34261380"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32969,curation_candidate,16108,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: oligonucleotide probe is used for CARD-FISH bacterial detection, not as a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""34237402"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32970,curation_candidate,16109,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: therapy-selection review/guidance for SMA medications; no primary safety endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""34231920"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32971,curation_candidate,16113,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of DMD gene editing/modulation therapies; no primary toxicity result is reported."", ""grounding_quote"": """", ""source_pmid"": ""34175043"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32972,curation_candidate,16118,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of RNA-targeted ASCVD therapeutics; tolerability statements are not primary safety results."", ""grounding_quote"": """", ""source_pmid"": ""34146170"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32973,curation_candidate,16120,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: antimiR-132 result is cardiac remodeling/function efficacy in a disease model, not toxicity."", ""grounding_quote"": """", ""source_pmid"": ""34112319"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32974,curation_candidate,16121,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of exon/gene therapies; safety-shortcoming statement is not a primary oligo toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""34097287"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32975,curation_candidate,16123,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: aptamer nanosensor detects food mycotoxins, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""34074391"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32976,curation_candidate,16129,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: summary of inclisiran LDL-C lowering with future safety data expected; no measured toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""34042340"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32977,curation_candidate,16143,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: RNAi crop biosensor/safety assessment is an agricultural diagnostic application, not therapeutic oligo evidence."", ""grounding_quote"": """", ""source_pmid"": ""33881427"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32978,curation_candidate,16146,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: oligonucleotide probes are used for E. coli detection, not as therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""33822415"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32979,curation_candidate,16149,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: HEPLISAV-B passage is a literature review/update and does not establish primary oligo toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""33783302"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32980,curation_candidate,16150,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: passage reports Lp(a)-lowering efficacy for pelacarsen and trial design, not a toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""33766265"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32981,curation_candidate,16162,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: DMD therapeutics review; no primary toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""33393390"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32982,curation_candidate,16170,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: protocol/method chapter; the adverse-effect statement is not presented as a primary measured toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""32789775"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32983,curation_candidate,16183,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: golodirsen review/summary; no primary measured safety endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""33025945"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32984,curation_candidate,16195,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: ELISA protocol quantifies LNA gapmers for future safety/PK assessment but reports no toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""32865795"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32985,curation_candidate,16196,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: inotersen overview says safety profile will be discussed but reports no primary safety result."", ""grounding_quote"": """", ""source_pmid"": ""32865784"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32986,curation_candidate,16215,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: primary trial excerpt reports Lp(a) reduction, not a safety or toxicity endpoint."", ""grounding_quote"": """", ""source_pmid"": ""31893580"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32987,curation_candidate,16229,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: viltolarsen review paper summarizes safety from trials but reports no primary safety result in this excerpt."", ""grounding_quote"": """", ""source_pmid"": ""31720560"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32988,curation_candidate,16251,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: LNA nanopore sensor is a diagnostic genotyping method, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""30441349"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32989,curation_candidate,16253,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: methods chapter for PMO exon inclusion; no measured toxicity endpoint is reported."", ""grounding_quote"": """", ""source_pmid"": ""30171560"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32990,curation_candidate,16255,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: zebrafish model/procedure for morpholino delivery and safety assessment, not an observed toxicity result."", ""grounding_quote"": """", ""source_pmid"": ""30171549"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32991,curation_candidate,16257,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of leukocyte-trafficking therapies; neurological-risk statements are not primary oligo toxicity evidence."", ""grounding_quote"": """", ""source_pmid"": ""30137311"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32992,curation_candidate,16266,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: review of DMD exon-skipping advances; no primary safety result is reported."", ""grounding_quote"": """", ""source_pmid"": ""29771317"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32993,curation_candidate,16267,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: overview of alicaforsen/SHP647; clear safety profile is non-specific review summary, not a primary endpoint."", ""grounding_quote"": """", ""source_pmid"": ""29757363"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32994,curation_candidate,16276,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: morpholine small-molecule mineralocorticoid antagonist, not a morpholino oligomer therapy."", ""grounding_quote"": """", ""source_pmid"": ""29300474"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32995,curation_candidate,16282,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 3 fail: LNA miR-31 inhibition result is anti-remodeling efficacy/target engagement, not toxicity."", ""grounding_quote"": """", ""source_pmid"": ""28865712"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32996,curation_candidate,16283,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 2 fail: alicaforsen review summarizes clinical/safety data; no primary toxicity result is reported."", ""grounding_quote"": """", ""source_pmid"": ""28670932"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32997,curation_candidate,16289,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: antisense against a bacterial gene is a research tool in a microbial survival assay, not a therapeutic oligo."", ""grounding_quote"": """", ""source_pmid"": ""28492351"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00
32998,curation_candidate,16304,human_curator_expand,apply_script.py,curator_rejected,reject,gr,"{""reason"": ""GATE 1 fail: morpholino-functionalized nanoparticles are HLA diagnostic probes, not therapeutic oligos."", ""grounding_quote"": """", ""source_pmid"": ""27720927"", ""candidate_domain"": ""toxicity""}",2026-06-07T23:20:28.301319+00:00